BLASTX 7.6.2
Query= UN22994 /QuerySize=1038
(1037 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O60119|YH75_SCHPO Vesicle-associated membrane protein-associa... 80 3e-014
sp|Q9P0L0|VAPA_HUMAN Vesicle-associated membrane protein-associa... 79 5e-014
sp|Q5R601|VAPA_PONAB Vesicle-associated membrane protein-associa... 79 5e-014
sp|Q9Z270|VAPA_RAT Vesicle-associated membrane protein-associate... 77 1e-013
sp|Q9WV55|VAPA_MOUSE Vesicle-associated membrane protein-associa... 77 2e-013
sp|Q16943|VP33_APLCA Vesicle-associated membrane protein/synapto... 76 3e-013
sp|A2VDZ9|VAPB_BOVIN Vesicle-associated membrane protein-associa... 75 5e-013
sp|Q0VCY1|VAPA_BOVIN Vesicle-associated membrane protein-associa... 75 7e-013
sp|O95292|VAPB_HUMAN Vesicle-associated membrane protein-associa... 75 9e-013
sp|Q10484|YDFC_SCHPO Uncharacterized protein C17C9.12 OS=Schizos... 71 1e-011
sp|Q9Z269|VAPB_RAT Vesicle-associated membrane protein-associate... 69 5e-011
sp|Q9QY76|VAPB_MOUSE Vesicle-associated membrane protein-associa... 69 6e-011
sp|P40075|SCS2_YEAST Vesicle-associated membrane protein-associa... 67 2e-010
sp|A5GFS8|VAPB_PIG Vesicle-associated membrane protein-associate... 65 5e-010
>sp|O60119|YH75_SCHPO Vesicle-associated membrane protein-associated protein
C16G5.05c OS=Schizosaccharomyces pombe GN=SPBC16G5.05c PE=1 SV=1
Length = 383
Score = 80 bits (195), Expect = 3e-014
Identities = 48/128 (37%), Positives = 67/128 (52%), Gaps = 5/128 (3%)
Frame = +1
Query: 199 NKTDNHVAFKVKTTNPKKYCVRPNTGVVLPRSTCEVLVTMQAQKEAPS-DMQCKDKFLLQ 375
N V FKVKTT PK YCVRPN+G + P+ST V V +QA KE P+ D +C+DKFL+Q
Sbjct: 27 NPNPEPVIFKVKTTAPKHYCVRPNSGKIEPKSTVNVQVLLQAMKEEPAPDFKCRDKFLIQ 86
Query: 376 GVIASPGVTPKDVTPEMF---SKEAGHLVEETKLRVTYVAPPQPPSPVHEGSEEGSSPRA 546
+ T F ++ G + + K+R Y + QPP + E S+
Sbjct: 87 SMAIGDADTSNVENYHEFWTEMEKQGRSIFDRKIRCVY-STKQPPQSADKQVENTSTSNP 145
Query: 547 SVSDNGTQ 570
VS G++
Sbjct: 146 PVSVEGSE 153
>sp|Q9P0L0|VAPA_HUMAN Vesicle-associated membrane protein-associated protein A
OS=Homo sapiens GN=VAPA PE=1 SV=3
Length = 249
Score = 79 bits (193), Expect = 5e-014
Identities = 53/176 (30%), Positives = 89/176 (50%), Gaps = 17/176 (9%)
Frame = +1
Query: 103 AMSNSELLTV--EPLDLQFPFELRKQISCSLYLTNKTDNHVAFKVKTTNPKKYCVRPNTG 276
AM+ E + V P DL+F ++ +L L N +D V FKVKTT P++YCVRPN+G
Sbjct: 7 AMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSG 66
Query: 277 VVLPRSTCEVLVTMQAQKEAPSDMQCKDKFLLQGVIASPGVTPKDVTPEMFSKEAGHLVE 456
++ P ST V V +Q P++ + K KF++Q + A P + + ++ + +
Sbjct: 67 IIDPGSTVTVSVMLQPFDYDPNE-KSKHKFMVQTIFAPPNTSDMEA---VWKEAKPDELM 122
Query: 457 ETKLRVTYVAP----------PQPPSPVHEGSEEGSSPRA-SVSDNGTQASEFSSQ 591
++KLR + P P P++ ++G P+ SVS N T+ + +
Sbjct: 123 DSKLRCVFEMPNENDKLNDMEPSKAVPLNASKQDGPMPKPHSVSLNDTETRKLMEE 178
>sp|Q5R601|VAPA_PONAB Vesicle-associated membrane protein-associated protein A
OS=Pongo abelii GN=VAPA PE=2 SV=2
Length = 249
Score = 79 bits (193), Expect = 5e-014
Identities = 53/176 (30%), Positives = 89/176 (50%), Gaps = 17/176 (9%)
Frame = +1
Query: 103 AMSNSELLTV--EPLDLQFPFELRKQISCSLYLTNKTDNHVAFKVKTTNPKKYCVRPNTG 276
AM+ E + V P DL+F ++ +L L N +D V FKVKTT P++YCVRPN+G
Sbjct: 7 AMAKHEQILVLDPPTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSG 66
Query: 277 VVLPRSTCEVLVTMQAQKEAPSDMQCKDKFLLQGVIASPGVTPKDVTPEMFSKEAGHLVE 456
++ P ST V V +Q P++ + K KF++Q + A P + + ++ + +
Sbjct: 67 IIDPGSTVTVSVMLQPFDYDPNE-KSKHKFMVQTIFAPPNTSDMEA---VWKEAKPDELM 122
Query: 457 ETKLRVTYVAP----------PQPPSPVHEGSEEGSSPRA-SVSDNGTQASEFSSQ 591
++KLR + P P P++ ++G P+ SVS N T+ + +
Sbjct: 123 DSKLRCVFEMPNENDKLNDMEPSKAVPLNASKQDGPMPKPHSVSLNDTETRKLMEE 178
>sp|Q9Z270|VAPA_RAT Vesicle-associated membrane protein-associated protein A
OS=Rattus norvegicus GN=Vapa PE=1 SV=3
Length = 249
Score = 77 bits (189), Expect = 1e-013
Identities = 53/176 (30%), Positives = 89/176 (50%), Gaps = 17/176 (9%)
Frame = +1
Query: 103 AMSNSELLTV--EPLDLQFPFELRKQISCSLYLTNKTDNHVAFKVKTTNPKKYCVRPNTG 276
AM+ E + V P DL+F ++ +L L N +D V FKVKTT P++YCVRPN+G
Sbjct: 7 AMAKHEQILVLDPPSDLKFKGPFTDVVTTNLKLQNPSDRKVCFKVKTTAPRRYCVRPNSG 66
Query: 277 VVLPRSTCEVLVTMQAQKEAPSDMQCKDKFLLQGVIASPGVTPKDVTPEMFSKEAGHLVE 456
V+ P S V V +Q P++ + K KF++Q + A P ++ + ++ + +
Sbjct: 67 VIDPGSIVTVSVMLQPFDYDPNE-KSKHKFMVQTIFAPPNISDMEA---VWKEAKPDELM 122
Query: 457 ETKLRVTYVAP----------PQPPSPVHEGSEEGSSPRA-SVSDNGTQASEFSSQ 591
++KLR + P P P++ ++G P+ SVS N T+ + +
Sbjct: 123 DSKLRCVFEMPNENDKLNDMEPSKAVPLNASKQDGPLPKPHSVSLNDTETRKLMEE 178
>sp|Q9WV55|VAPA_MOUSE Vesicle-associated membrane protein-associated protein A
OS=Mus musculus GN=Vapa PE=1 SV=2
Length = 249
Score = 77 bits (188), Expect = 2e-013
Identities = 52/176 (29%), Positives = 89/176 (50%), Gaps = 17/176 (9%)
Frame = +1
Query: 103 AMSNSELLTV--EPLDLQFPFELRKQISCSLYLTNKTDNHVAFKVKTTNPKKYCVRPNTG 276
AM+ E + V P DL+F ++ +L L N +D V FKVKTT P++YCVRPN+G
Sbjct: 7 AMAKHEQILVLDPPSDLKFKGPFTDVVTTNLKLQNPSDRKVCFKVKTTAPRRYCVRPNSG 66
Query: 277 VVLPRSTCEVLVTMQAQKEAPSDMQCKDKFLLQGVIASPGVTPKDVTPEMFSKEAGHLVE 456
++ P S V V +Q P++ + K KF++Q + A P ++ + ++ + +
Sbjct: 67 IIDPGSIVTVSVMLQPFDYDPNE-KSKHKFMVQTIFAPPNISDMEA---VWKEAKPDELM 122
Query: 457 ETKLRVTYVAP----------PQPPSPVHEGSEEGSSPRA-SVSDNGTQASEFSSQ 591
++KLR + P P P++ ++G P+ SVS N T+ + +
Sbjct: 123 DSKLRCVFEMPNENDKLNDMEPSKAVPLNASKQDGPLPKPHSVSLNDTETRKLMEE 178
>sp|Q16943|VP33_APLCA Vesicle-associated membrane protein/synaptobrevin-binding
protein OS=Aplysia californica PE=2 SV=1
Length = 260
Score = 76 bits (186), Expect = 3e-013
Identities = 52/162 (32%), Positives = 85/162 (52%), Gaps = 10/162 (6%)
Frame = +1
Query: 109 SNSELLTVEPL-DLQFPFELRKQISCSLYLTNKTDNHVAFKVKTTNPKKYCVRPNTGVVL 285
S+ + L +EP +L+F ++ L L+N TD + FKVKTT PK+YCVRPN+G++
Sbjct: 3 SHEQALILEPAGELRFKGPFTDVVTADLKLSNPTDRRICFKVKTTAPKRYCVRPNSGILE 62
Query: 286 PRSTCEVLVTMQAQKEAPSDMQCKDKFLLQGVIASPGVTPKDVTPEMFSKEA-GHLVEET 462
P+++ V V +Q P++ K KF++Q + A V + E+ K+A + +T
Sbjct: 63 PKTSIAVAVMLQPFNYDPNEKN-KHKFMVQSMYAPDHVVE---SQELLWKDAPPESLMDT 118
Query: 463 KLRVTYVAP----PQPPSPVHEGSEEGSSPRASVSDNGTQAS 576
KLR + P P S ++ G+ S ++ T AS
Sbjct: 119 KLRCVFEMPDGSHQAPASDASRATDAGAHFSESALEDPTVAS 160
>sp|A2VDZ9|VAPB_BOVIN Vesicle-associated membrane protein-associated protein B
OS=Bos taurus GN=VAPB PE=2 SV=1
Length = 243
Score = 75 bits (184), Expect = 5e-013
Identities = 65/242 (26%), Positives = 116/242 (47%), Gaps = 17/242 (7%)
Frame = +1
Query: 118 ELLTVEPL-DLQFPFELRKQISCSLYLTNKTDNHVAFKVKTTNPKKYCVRPNTGVVLPRS 294
++L++EP +L+F ++ +L L N TD +V FKVKTT P++YCVRPN+G++ +
Sbjct: 6 QVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGA 65
Query: 295 TCEVLVTMQAQKEAPSDMQCKDKFLLQGVIASPGVTPKDVTP-EMFSKEA-GHLVEETKL 468
+ V V +Q P++ + K KF++Q + A P D + E KEA + ++KL
Sbjct: 66 SINVSVMLQPFDYDPNE-KSKHKFMVQSMFA-----PTDTSDMEAVWKEAKPEDLMDSKL 119
Query: 469 RVTYVAPPQPPSPVHEGSEEGSSPRASVSDNGTQASEFSSQRHIADKVEPQENTSEARAL 648
R + P + P + AS ++ T + SS + + E ++
Sbjct: 120 RCVFELPAENDKPHDVEINKIIPTTASKTETPTVSKALSSSLDDTEVKKVMEECKRLQSE 179
Query: 649 ITKLTEEKQSALQLNNKLQRELDQLRRDS--------KRGQSGMPLMYVLLVGLIGLILG 804
+ +L EE + + + R+ Q + + G S L V+L ++G+I+G
Sbjct: 180 VQRLREENKQFKEEDGLRMRKTAQSNSPAPASAMAGKEEGLSTRLLALVVLFFIVGVIIG 239
Query: 805 YI 810
I
Sbjct: 240 KI 241
>sp|Q0VCY1|VAPA_BOVIN Vesicle-associated membrane protein-associated protein A
OS=Bos taurus GN=VAPA PE=2 SV=1
Length = 249
Score = 75 bits (183), Expect = 7e-013
Identities = 47/158 (29%), Positives = 81/158 (51%), Gaps = 17/158 (10%)
Frame = +1
Query: 136 PLDLQFPFELRKQISCSLYLTNKTDNHVAFKVKTTNPKKYCVRPNTGVVLPRSTCEVLVT 315
P DL+F ++ +L L N +D V FKVKTT P++YCVRPN+G++ P T V V
Sbjct: 20 PTDLKFKGPFTDVVTTNLKLRNPSDRKVCFKVKTTAPRRYCVRPNSGIIDPGLTVTVSVM 79
Query: 316 MQAQKEAPSDMQCKDKFLLQGVIASPGVTPKDVTPEMFSKEAGHLVEETKLRVTYVAP-- 489
+Q P++ + K KF++Q + A P ++ + ++ + + ++KLR + P
Sbjct: 80 LQPFDYDPNE-KSKHKFMVQTIFAPPNISDMEA---VWKEAKPDELMDSKLRCVFEMPNE 135
Query: 490 --------PQPPSPVHEGSEEGSSPR---ASVSDNGTQ 570
P P++ ++G P+ S+SD T+
Sbjct: 136 NDKLNDMEPSKAVPLNAAKQDGPVPKPHSVSLSDTETR 173
>sp|O95292|VAPB_HUMAN Vesicle-associated membrane protein-associated protein B/C
OS=Homo sapiens GN=VAPB PE=1 SV=3
Length = 243
Score = 75 bits (182), Expect = 9e-013
Identities = 67/242 (27%), Positives = 117/242 (48%), Gaps = 17/242 (7%)
Frame = +1
Query: 118 ELLTVEPL-DLQFPFELRKQISCSLYLTNKTDNHVAFKVKTTNPKKYCVRPNTGVVLPRS 294
++L++EP +L+F ++ +L L N TD +V FKVKTT P++YCVRPN+G++ +
Sbjct: 6 QVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGA 65
Query: 295 TCEVLVTMQAQKEAPSDMQCKDKFLLQGVIASPGVTPKDVTP-EMFSKEA-GHLVEETKL 468
+ V V +Q P++ + K KF++Q + A P D + E KEA + ++KL
Sbjct: 66 SINVSVMLQPFDYDPNE-KSKHKFMVQSMFA-----PTDTSDMEAVWKEAKPEDLMDSKL 119
Query: 469 RVTYVAPPQPPSPVHEGSEEGSSPRASVSDNGTQASEFSSQRHIADKVEPQENTSEARAL 648
R + P + P + S AS ++ + SS + + E +
Sbjct: 120 RCVFELPAENDKPHDVEINKIISTTASKTETPIVSKSLSSSLDDTEVKKVMEECKRLQGE 179
Query: 649 ITKLTEE-----KQSALQLNNKLQRE--LDQLRRDSK-RGQSGMPLMYVLLVGLIGLILG 804
+ +L EE ++ L++ +Q + L K G S L V+L ++G+I+G
Sbjct: 180 VQRLREENKQFKEEDGLRMRKTVQSNSPISALAPTGKEEGLSTRLLALVVLFFIVGVIIG 239
Query: 805 YI 810
I
Sbjct: 240 KI 241
>sp|Q10484|YDFC_SCHPO Uncharacterized protein C17C9.12 OS=Schizosaccharomyces
pombe GN=SPAC17C9.12 PE=1 SV=2
Length = 319
Score = 71 bits (173), Expect = 1e-011
Identities = 40/115 (34%), Positives = 60/115 (52%), Gaps = 2/115 (1%)
Frame = +1
Query: 151 FPFELRKQISCSLYLTNKTDNHVAFKVKTTNPKKYCVRPNTGVVLPRSTCEVLVTMQAQK 330
FP L + + C L L N + FKVKTT PK+YCVRPN G + S V V +Q
Sbjct: 11 FPRPLTRLVKCDLELRNTAPYPIGFKVKTTAPKQYCVRPNGGRIEANSAVSVEVILQPLD 70
Query: 331 EAPS-DMQCKDKFLLQGVIASPGVTPKDVTPEMFSKEAGHLVEETKLRVTYVAPP 492
P+ +C+DKFL+Q P + D+ +++++ + + E K+R Y P
Sbjct: 71 HEPAPGTKCRDKFLVQSTELKPELQGMDIA-DIWTQVSKANISERKIRCVYSEGP 124
>sp|Q9Z269|VAPB_RAT Vesicle-associated membrane protein-associated protein B
OS=Rattus norvegicus GN=Vapb PE=1 SV=3
Length = 243
Score = 69 bits (167), Expect = 5e-011
Identities = 41/131 (31%), Positives = 74/131 (56%), Gaps = 5/131 (3%)
Frame = +1
Query: 118 ELLTVEPL-DLQFPFELRKQISCSLYLTNKTDNHVAFKVKTTNPKKYCVRPNTGVVLPRS 294
++L++EP +L+F ++ +L L N TD +V FKVKTT P++YCVRPN+GV+ +
Sbjct: 6 QVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGVIDAGA 65
Query: 295 TCEVLVTMQAQKEAPSDMQCKDKFLLQGVIASPGVTPKDVTPEMFSKEAGHLVEETKLRV 474
+ V V +Q P++ + K KF++Q + A P + + ++ + + ++KLR
Sbjct: 66 SLNVSVMLQPFDYDPNE-KSKHKFMVQSMFAPPDTSDMEA---VWKEAKPEDLMDSKLRC 121
Query: 475 TYVAPPQPPSP 507
+ P + P
Sbjct: 122 VFELPAENAKP 132
>sp|Q9QY76|VAPB_MOUSE Vesicle-associated membrane protein-associated protein B
OS=Mus musculus GN=Vapb PE=2 SV=3
Length = 243
Score = 69 bits (166), Expect = 6e-011
Identities = 41/131 (31%), Positives = 74/131 (56%), Gaps = 5/131 (3%)
Frame = +1
Query: 118 ELLTVEPL-DLQFPFELRKQISCSLYLTNKTDNHVAFKVKTTNPKKYCVRPNTGVVLPRS 294
++L++EP +L+F ++ +L L N TD +V FKVKTT P++YCVRPN+GV+ +
Sbjct: 6 QVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTVPRRYCVRPNSGVIDAGA 65
Query: 295 TCEVLVTMQAQKEAPSDMQCKDKFLLQGVIASPGVTPKDVTPEMFSKEAGHLVEETKLRV 474
+ V V +Q P++ + K KF++Q + A P + + ++ + + ++KLR
Sbjct: 66 SLNVSVMLQPFDYDPNE-KSKHKFMVQSMFAPPDTSDMEA---VWKEAKPEDLMDSKLRC 121
Query: 475 TYVAPPQPPSP 507
+ P + P
Sbjct: 122 VFELPAENAKP 132
>sp|P40075|SCS2_YEAST Vesicle-associated membrane protein-associated protein
SCS2 OS=Saccharomyces cerevisiae GN=SCS2 PE=1 SV=3
Length = 244
Score = 67 bits (161), Expect = 2e-010
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 11/155 (7%)
Frame = +1
Query: 130 VEPLDLQFPFELRKQISCSLYLTNKTDNHVAFKVKTTNPKKYCVRPNTGVVLPRSTCEVL 309
+ P L + L +Q + ++N +D +AFKVKTT PK YCVRPN VV P T +V
Sbjct: 6 ISPDVLVYKSPLTEQSTEYASISNNSDQTIAFKVKTTAPKFYCVRPNAAVVAPGETIQVQ 65
Query: 310 VTMQAQKEAP-SDMQCKDKFLLQGVIASP----GVTPKDVTPEMFSKEAGHLVEETKLRV 474
V E P +D +C+DKFL+ + SP G DV ++ ++ + + K++V
Sbjct: 66 VIFLGLTEEPAADFKCRDKFLVI-TLPSPYDLNGKAVADVWSDLEAEFKQQAISK-KIKV 123
Query: 475 TYVAPPQPPSPVHEGSEEGSSPRASVSDNGTQASE 579
Y+ P VH + + Q SE
Sbjct: 124 KYLISPD----VHPAQNQNIQENKETVEPVVQDSE 154
>sp|A5GFS8|VAPB_PIG Vesicle-associated membrane protein-associated protein B
OS=Sus scrofa GN=VAPB PE=3 SV=1
Length = 243
Score = 65 bits (158), Expect = 5e-010
Identities = 45/133 (33%), Positives = 75/133 (56%), Gaps = 9/133 (6%)
Frame = +1
Query: 118 ELLTVEPL-DLQFPFELRKQISCSLYLTNKTDNHVAFKVKTTNPKKYCVRPNTGVVLPRS 294
++L++EP +L+F ++ +L L N TD +V FKVKTT P++YCVRPN+G++ +
Sbjct: 6 QVLSLEPQHELKFRGPFTDVVTTNLKLGNPTDRNVCFKVKTTAPRRYCVRPNSGIIDAGA 65
Query: 295 TCEVLVTMQAQKEAPSDMQCKDKFLLQGVIASPGVTPKDVTP-EMFSKEA-GHLVEETKL 468
+ V V +Q P++ + K KF++Q + A P D + E KEA + ++KL
Sbjct: 66 SINVSVMLQPFDYDPNE-KSKHKFMVQSMFA-----PADTSDMEAAWKEAKPEDLMDSKL 119
Query: 469 RVTYVAPPQPPSP 507
R + P + P
Sbjct: 120 RCVFELPAENDKP 132
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,819,846,109
Number of Sequences: 518415
Number of Extensions: 95819846109
Number of Successful Extensions: 619733697
Number of sequences better than 0.0: 0
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