BLASTX 7.6.2
Query= UN23065 /QuerySize=899
(898 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus ... 84 1e-015
sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus... 82 3e-015
sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo... 77 1e-013
sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos ... 77 2e-013
sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo... 76 3e-013
sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus ... 76 3e-013
sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Dani... 76 3e-013
sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabido... 75 4e-013
sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=R... 75 6e-013
sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN... 75 6e-013
sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN... 75 7e-013
sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropica... 71 1e-011
sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevi... 70 1e-011
sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevi... 70 1e-011
sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabido... 70 2e-011
sp|Q9C1X4|YKW3_SCHPO Uncharacterized RING finger protein P32A8.0... 68 9e-011
sp|Q06003|GOLI_DROME Protein goliath OS=Drosophila melanogaster ... 62 5e-009
sp|Q6AY01|RN133_RAT E3 ubiquitin-protein ligase RNF133 OS=Rattus... 62 6e-009
sp|Q14B02|RN133_MOUSE E3 ubiquitin-protein ligase RNF133 OS=Mus ... 61 8e-009
sp|Q6NRX0|RN149_XENLA E3 ubiquitin-protein ligase RNF149 OS=Xeno... 61 1e-008
>sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus musculus
GN=Rnf181 PE=2 SV=1
Length = 165
Score = 84 bits (206), Expect = 1e-015
Identities = 38/92 (41%), Positives = 54/92 (58%), Gaps = 2/92 (2%)
Frame = -3
Query: 557 GLFESREEGHPPASKASIDAMPNVDVVSCVGE--CVICLEEWKAEETVKEMPCKHKFHGG 384
GL + PPA+KA ++++P + S + C +CL E++AEETV EMPC H FH
Sbjct: 54 GLVDWEHHLPPPAAKAVVESLPRTVISSAKADLKCPVCLLEFEAEETVIEMPCHHLFHSN 113
Query: 383 CIEKWLGLHGSCPVCRYDMPVDGDEVGKKSND 288
CI WL SCP+CR+++P D D + D
Sbjct: 114 CILPWLSKTNSCPLCRHELPTDDDSYEEHKKD 145
>sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus norvegicus
GN=Rnf181 PE=1 SV=1
Length = 165
Score = 82 bits (202), Expect = 3e-015
Identities = 38/92 (41%), Positives = 53/92 (57%), Gaps = 2/92 (2%)
Frame = -3
Query: 557 GLFESREEGHPPASKASIDAMPNVDVVSCVGE--CVICLEEWKAEETVKEMPCKHKFHGG 384
GL + PPA+KA ++++P + S E C +CL E++ EETV EMPC H FH
Sbjct: 54 GLVDWEHHLPPPAAKAVVESLPRTVIRSSKAELKCPVCLLEFEEEETVIEMPCHHLFHSN 113
Query: 383 CIEKWLGLHGSCPVCRYDMPVDGDEVGKKSND 288
CI WL SCP+CR+++P D D + D
Sbjct: 114 CILPWLSKTNSCPLCRHELPTDDDSYEEHKKD 145
>sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo sapiens
GN=RNF181 PE=1 SV=1
Length = 153
Score = 77 bits (188), Expect = 1e-013
Identities = 34/82 (41%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Frame = -3
Query: 527 PPASKASIDAMPNVDVVSCVGE--CVICLEEWKAEETVKEMPCKHKFHGGCIEKWLGLHG 354
PPA+K ++ +P + E C +CL E++ EET EMPC H FH CI WL
Sbjct: 52 PPAAKTVVENLPRTVIRGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSSCILPWLSKTN 111
Query: 353 SCPVCRYDMPVDGDEVGKKSND 288
SCP+CRY++P D D + D
Sbjct: 112 SCPLCRYELPTDDDTYEEHRRD 133
>sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos taurus
GN=RNF181 PE=2 SV=1
Length = 153
Score = 77 bits (187), Expect = 2e-013
Identities = 33/82 (40%), Positives = 47/82 (57%), Gaps = 2/82 (2%)
Frame = -3
Query: 527 PPASKASIDAMPNVDVVSCVGE--CVICLEEWKAEETVKEMPCKHKFHGGCIEKWLGLHG 354
PPA+K +++ +P + E C +CL E++ EET EMPC H FH CI WL
Sbjct: 52 PPAAKTAVENLPRTVIRGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSNCILPWLSKTN 111
Query: 353 SCPVCRYDMPVDGDEVGKKSND 288
SCP+CR+++P D D + D
Sbjct: 112 SCPLCRHELPTDDDTYEEHKRD 133
>sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo sapiens
GN=RNF115 PE=1 SV=2
Length = 304
Score = 76 bits (185), Expect = 3e-013
Identities = 39/101 (38%), Positives = 58/101 (57%), Gaps = 7/101 (6%)
Frame = -3
Query: 581 SGLNPLLRGLFESREE-GHPPASKASIDAMPNVDV----VSCVGECVICLEEWKAEETVK 417
+GL+ ++ L E G PPA K I ++P V V V EC +C E++ EE V+
Sbjct: 183 TGLDAIVTQLLGQLENTGPPPADKEKITSLPTVTVTQEQVDMGLECPVCKEDYTVEEEVR 242
Query: 416 EMPCKHKFHGGCIEKWLGLHGSCPVCRYDMPVDGDEVGKKS 294
++PC H FH CI WL LH +CPVCR + +G++ ++S
Sbjct: 243 QLPCNHFFHSSCIVPWLELHDTCPVCRKSL--NGEDSTRQS 281
>sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus musculus
GN=Rnf115 PE=1 SV=1
Length = 305
Score = 76 bits (185), Expect = 3e-013
Identities = 37/87 (42%), Positives = 51/87 (58%), Gaps = 5/87 (5%)
Frame = -3
Query: 581 SGLNPLLRGLFESREE-GHPPASKASIDAMPNVDV----VSCVGECVICLEEWKAEETVK 417
+GL+ ++ L E G PPA K I ++P V V V+ EC +C E++ EE V+
Sbjct: 184 TGLDAIVTQLLGQLENTGPPPADKEKITSLPTVTVTQEQVNTGLECPVCKEDYTVEEKVR 243
Query: 416 EMPCKHKFHGGCIEKWLGLHGSCPVCR 336
++PC H FH CI WL LH +CPVCR
Sbjct: 244 QLPCNHFFHSSCIVPWLELHDTCPVCR 270
>sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Danio rerio
GN=rnf181 PE=2 SV=2
Length = 156
Score = 76 bits (185), Expect = 3e-013
Identities = 34/84 (40%), Positives = 51/84 (60%), Gaps = 4/84 (4%)
Frame = -3
Query: 527 PPASKASIDAMPNVDVVSCVGE----CVICLEEWKAEETVKEMPCKHKFHGGCIEKWLGL 360
PPA+KA + ++P V + + C +CL E++ +E+V+EMPCKH FH GCI WL
Sbjct: 53 PPAAKAVVQSLPVVIISPEQADKGVKCPVCLLEFEEQESVREMPCKHLFHTGCILPWLNK 112
Query: 359 HGSCPVCRYDMPVDGDEVGKKSND 288
SCP+CR ++P D + + D
Sbjct: 113 TNSCPLCRLELPTDNADYEEFKKD 136
>sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabidopsis thaliana
GN=CIP8 PE=1 SV=1
Length = 334
Score = 75 bits (184), Expect = 4e-013
Identities = 34/79 (43%), Positives = 47/79 (59%), Gaps = 4/79 (5%)
Frame = -3
Query: 533 GHPPASKASIDAMPNVDVVSCVGE----CVICLEEWKAEETVKEMPCKHKFHGGCIEKWL 366
G PPA+K++I+A+ +V S GE C +C + ET K++PC H +HG CI WL
Sbjct: 229 GAPPAAKSAIEALETFEVSSSEGEMVMVCAVCKDGMVMGETGKKLPCGHCYHGDCIVPWL 288
Query: 365 GLHGSCPVCRYDMPVDGDE 309
G SCPVCR+ + D E
Sbjct: 289 GTRNSCPVCRFQLETDDAE 307
>sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=RNF126 PE=2
SV=1
Length = 313
Score = 75 bits (183), Expect = 6e-013
Identities = 44/129 (34%), Positives = 63/129 (48%), Gaps = 11/129 (8%)
Frame = -3
Query: 584 SSGLNPLLRGLFESREE-GHPPASKASIDAMPNVDV----VSCVGECVICLEEWKAEETV 420
++GL+ ++ L E G PPA K I A+P V V V EC +C +++ E V
Sbjct: 186 ANGLDAIITQLLNQFENTGPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDYGLGEHV 245
Query: 419 KEMPCKHKFHGGCIEKWLGLHGSCPVCRYDMPVDGDEVGKKSNDGREIWVRFSFNGGGRS 240
+++PC H FH GCI WL H SCPVCR + G+ + SF+ S
Sbjct: 246 RQLPCNHLFHDGCIVPWLEQHDSCPVCRKSL------TGQNTATDPPGLAGVSFSSSSSS 299
Query: 239 VRDSSGHED 213
S G+E+
Sbjct: 300 SSSSPGNEN 308
>sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN=RNF126 PE=1
SV=1
Length = 326
Score = 75 bits (183), Expect = 6e-013
Identities = 37/88 (42%), Positives = 50/88 (56%), Gaps = 5/88 (5%)
Frame = -3
Query: 584 SSGLNPLLRGLFESREE-GHPPASKASIDAMPNVDV----VSCVGECVICLEEWKAEETV 420
++GL+ ++ L E G PPA K I A+P V V V EC +C +++ E V
Sbjct: 183 ANGLDAIITQLLNQFENTGPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDYALGERV 242
Query: 419 KEMPCKHKFHGGCIEKWLGLHGSCPVCR 336
+++PC H FH GCI WL H SCPVCR
Sbjct: 243 RQLPCNHLFHDGCIVPWLEQHDSCPVCR 270
>sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN=Rnf126 PE=1
SV=1
Length = 313
Score = 75 bits (182), Expect = 7e-013
Identities = 37/88 (42%), Positives = 50/88 (56%), Gaps = 5/88 (5%)
Frame = -3
Query: 584 SSGLNPLLRGLFESREE-GHPPASKASIDAMPNVDV----VSCVGECVICLEEWKAEETV 420
++GL+ ++ L E G PPA K I A+P V V V EC +C E++ E+V
Sbjct: 185 ANGLDTIITQLLNQFENTGPPPADKEKIQALPTVPVTEEHVGSGLECPVCKEDYALGESV 244
Query: 419 KEMPCKHKFHGGCIEKWLGLHGSCPVCR 336
+++PC H FH CI WL H SCPVCR
Sbjct: 245 RQLPCNHLFHDSCIVPWLEQHDSCPVCR 272
>sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropicalis GN=rnf126
PE=2 SV=1
Length = 311
Score = 71 bits (172), Expect = 1e-011
Identities = 33/88 (37%), Positives = 49/88 (55%), Gaps = 5/88 (5%)
Frame = -3
Query: 584 SSGLNPLLRGLFESREE-GHPPASKASIDAMPNVDV----VSCVGECVICLEEWKAEETV 420
++GL+ ++ L E G PPA I A+P + + V EC +C E++ E+V
Sbjct: 181 ANGLDTIITQLLNQFENTGPPPADTEKIQALPTIQITEEHVGSGLECPVCKEDYTVGESV 240
Query: 419 KEMPCKHKFHGGCIEKWLGLHGSCPVCR 336
+++PC H FH CI WL H +CPVCR
Sbjct: 241 RQLPCNHLFHNDCIIPWLEQHDTCPVCR 268
>sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevis GN=rnf126-a
PE=2 SV=1
Length = 312
Score = 70 bits (171), Expect = 1e-011
Identities = 33/88 (37%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Frame = -3
Query: 584 SSGLNPLLRGLFESREE-GHPPASKASIDAMPNVDV----VSCVGECVICLEEWKAEETV 420
++GL+ ++ L E G PPA I A+P + + V EC +C E++ E V
Sbjct: 182 ANGLDTIITQLLNQFENTGPPPADNEKIQALPTIQITEEHVGSGLECPVCKEDYTVGECV 241
Query: 419 KEMPCKHKFHGGCIEKWLGLHGSCPVCR 336
+++PC H FH CI WL H +CPVCR
Sbjct: 242 RQLPCNHLFHNDCIIPWLEQHDTCPVCR 269
>sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevis GN=rnf126-b
PE=2 SV=1
Length = 312
Score = 70 bits (171), Expect = 1e-011
Identities = 34/88 (38%), Positives = 50/88 (56%), Gaps = 5/88 (5%)
Frame = -3
Query: 584 SSGLNPLLRGLFESREE-GHPPASKASIDAMPNVDVV-SCVG---ECVICLEEWKAEETV 420
++GL+ ++ L E G PPA I A+P + + VG EC +C E++ E+V
Sbjct: 182 ANGLDTIITQLLNQFENTGPPPADTDKIQALPTIQITEEHVGFGLECPVCKEDYTVGESV 241
Query: 419 KEMPCKHKFHGGCIEKWLGLHGSCPVCR 336
+++PC H FH CI WL H +CPVCR
Sbjct: 242 RQLPCNHLFHNDCIIPWLEQHDTCPVCR 269
>sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabidopsis thaliana
GN=AIP2 PE=1 SV=1
Length = 310
Score = 70 bits (170), Expect = 2e-011
Identities = 30/77 (38%), Positives = 47/77 (61%), Gaps = 7/77 (9%)
Frame = -3
Query: 527 PPASKASIDAMPNV----DVVSCVG---ECVICLEEWKAEETVKEMPCKHKFHGGCIEKW 369
PPASK ++ +P + +++ G EC IC E + ++E+PCKH FH C++ W
Sbjct: 201 PPASKEVVEKLPVIIFTEELLKKFGAEAECCICKENLVIGDKMQELPCKHTFHPPCLKPW 260
Query: 368 LGLHGSCPVCRYDMPVD 318
L H SCP+CR+++P D
Sbjct: 261 LDEHNSCPICRHELPTD 277
>sp|Q9C1X4|YKW3_SCHPO Uncharacterized RING finger protein P32A8.03c
OS=Schizosaccharomyces pombe GN=SPAP32A8.03c PE=2 SV=1
Length = 513
Score = 68 bits (164), Expect = 9e-011
Identities = 33/104 (31%), Positives = 56/104 (53%), Gaps = 8/104 (7%)
Frame = -3
Query: 578 GLNPLLRGLFESREEGHPPASKASIDAM-------PNVDVVSCVGECVICLEEWKAEETV 420
GL+ ++ L E + +GH + A D + P +++ GEC IC+E +K + V
Sbjct: 351 GLDDIISQLME-QAQGHNAPAPAPEDVIAKMKVQKPPKELIDEEGECTICMEMFKINDDV 409
Query: 419 KEMPCKHKFHGGCIEKWLGLHGSCPVCRYDMPVDGDEVGKKSND 288
++PCKH FH CI+ WL ++G+C +CR + + + S D
Sbjct: 410 IQLPCKHYFHENCIKPWLRVNGTCAICRAPVDPNSQQRNNTSTD 453
>sp|Q06003|GOLI_DROME Protein goliath OS=Drosophila melanogaster GN=gol PE=2
SV=3
Length = 461
Score = 62 bits (149), Expect = 5e-009
Identities = 21/45 (46%), Positives = 33/45 (73%)
Frame = -3
Query: 461 CVICLEEWKAEETVKEMPCKHKFHGGCIEKWLGLHGSCPVCRYDM 327
C IC+E +K +T++ +PCKH+FH CI+ WL H +CP+C+ D+
Sbjct: 303 CAICIEAYKPTDTIRILPCKHEFHKNCIDPWLIEHRTCPMCKLDV 347
>sp|Q6AY01|RN133_RAT E3 ubiquitin-protein ligase RNF133 OS=Rattus norvegicus
GN=Rnf133 PE=2 SV=1
Length = 381
Score = 62 bits (148), Expect = 6e-009
Identities = 25/59 (42%), Positives = 35/59 (59%), Gaps = 6/59 (10%)
Frame = -3
Query: 503 DAMPNVDVVSCVGECVICLEEWKAEETVKEMPCKHKFHGGCIEKWLGLHGSCPVCRYDM 327
+ PN D CVIC E +K E V+ + CKH FH CI+ W+ HG+CP+C+ D+
Sbjct: 248 EVSPNAD------SCVICFEAYKPNEIVRILTCKHFFHKNCIDPWILAHGTCPMCKCDI 300
>sp|Q14B02|RN133_MOUSE E3 ubiquitin-protein ligase RNF133 OS=Mus musculus
GN=Rnf133 PE=1 SV=1
Length = 382
Score = 61 bits (147), Expect = 8e-009
Identities = 25/56 (44%), Positives = 34/56 (60%), Gaps = 6/56 (10%)
Frame = -3
Query: 494 PNVDVVSCVGECVICLEEWKAEETVKEMPCKHKFHGGCIEKWLGLHGSCPVCRYDM 327
PN D CVIC E +K E V+ + CKH FH CI+ W+ HG+CP+C+ D+
Sbjct: 251 PNAD------SCVICFEAYKPNEIVRILTCKHFFHKNCIDPWILAHGTCPMCKCDI 300
>sp|Q6NRX0|RN149_XENLA E3 ubiquitin-protein ligase RNF149 OS=Xenopus laevis
GN=rnf149 PE=2 SV=1
Length = 397
Score = 61 bits (146), Expect = 1e-008
Identities = 33/106 (31%), Positives = 55/106 (51%), Gaps = 2/106 (1%)
Frame = -3
Query: 461 CVICLEEWKAEETVKEMPCKHKFHGGCIEKWLGLHGSCPVCRYDMPVDGDEVGKKSNDGR 282
C +C+E +K ++ V+ +PCKH FH CI+ WL H +CP+C+ D+ + + +
Sbjct: 264 CAVCIENYKTKDLVRILPCKHIFHRLCIDPWLIEHRTCPMCKLDV-IKALGFWVEPEETL 322
Query: 281 EIWVRFSFNGGGRSVRDSSGHEDGNSDGDGNIVTSGGTRPVLESEN 144
+I V S G S+ S ++ S +GN + S T L+ N
Sbjct: 323 DIHVPDSIAGSSLSIGTVSITQE-ESRSEGNNLPSSSTGSSLQQSN 367
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,819,846,109
Number of Sequences: 518415
Number of Extensions: 95819846109
Number of Successful Extensions: 619733697
Number of sequences better than 0.0: 0
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