BLASTX 7.6.2
Query= UN23123 /QuerySize=939
(938 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9LTI3|MPU1_ARATH Mannose-P-dolichol utilization defect 1 pro... 360 9e-099
sp|Q9VMW8|MPU1_DROME Mannose-P-dolichol utilization defect 1 pro... 122 5e-027
sp|O75352|MPU1_HUMAN Mannose-P-dolichol utilization defect 1 pro... 120 2e-026
sp|Q9R0Q9|MPU1_MOUSE Mannose-P-dolichol utilization defect 1 pro... 119 3e-026
sp|Q60441|MPU1_CRIGR Mannose-P-dolichol utilization defect 1 pro... 117 1e-025
sp|Q20157|MPU1_CAEEL Mannose-P-dolichol utilization defect 1 pro... 114 1e-024
sp|Q8N755|PQLC3_HUMAN PQ-loop repeat-containing protein 3 OS=Hom... 68 9e-011
sp|Q8C6U2|PQLC3_MOUSE PQ-loop repeat-containing protein 3 OS=Mus... 59 4e-008
>sp|Q9LTI3|MPU1_ARATH Mannose-P-dolichol utilization defect 1 protein homolog
OS=Arabidopsis thaliana GN=At5g59470 PE=2 SV=1
Length = 239
Score = 360 bits (923), Expect = 9e-099
Identities = 176/223 (78%), Positives = 203/223 (91%)
Frame = +1
Query: 55 MEYLGIDLSCAMGSLRNGEFPEKDCLLPLISKLLGYILVAASITVKLPQIMKIVHHKSVR 234
M+YLGIDLSCA+GSLRNGEFP KDCLLPLISKLLGY LVAAS+TVKLPQIMKIV +KSV+
Sbjct: 1 MDYLGIDLSCAIGSLRNGEFPAKDCLLPLISKLLGYFLVAASMTVKLPQIMKIVDNKSVK 60
Query: 235 GLSVVAFELEVVGYTISLAYCLHKGLPFSAFGEMAFLLIQALILVACIYYYSQPVPMTTW 414
GLSVVAFELEV+GYTISLAYCL+K LPFSAFGE+AFLLIQALILVACIYY+SQP+ +TTW
Sbjct: 61 GLSVVAFELEVIGYTISLAYCLNKDLPFSAFGELAFLLIQALILVACIYYFSQPLSVTTW 120
Query: 415 VRALLYCAVAPTVLAGQINPTLFDALYASQHAIFLFARLPQIWKNFKNKSTGELSFLTFF 594
V+A+LY A+APTV AG+I+P LF+ALYAS+H IFL AR+PQIWKNF+NKSTG+LSFLT
Sbjct: 121 VKAILYFAIAPTVFAGKIDPFLFEALYASKHLIFLSARIPQIWKNFRNKSTGQLSFLTCL 180
Query: 595 MNFAGSIVRVFTSIQENAPVSILTGFALGVFTNGTILSQILLY 723
MNF G++ RVFTSIQE AP+S+L G L +FTNG I+SQILLY
Sbjct: 181 MNFGGALARVFTSIQEKAPLSMLLGIVLSIFTNGIIMSQILLY 223
>sp|Q9VMW8|MPU1_DROME Mannose-P-dolichol utilization defect 1 protein homolog
OS=Drosophila melanogaster GN=CG3792 PE=1 SV=2
Length = 252
Score = 122 bits (304), Expect = 5e-027
Identities = 74/228 (32%), Positives = 121/228 (53%), Gaps = 4/228 (1%)
Frame = +1
Query: 112 FPEKDCLLPLISKLLGYILVAASITVKLPQIMKIVHHKSVRGLSVVAFELEVVGYTISLA 291
F + C L+SK LG ++A S+ VK+PQ++KI++ KS G+++V L+++ + L+
Sbjct: 27 FLDVPCFKALLSKGLGLAIIAGSVLVKVPQVLKILNSKSGEGINIVGVVLDLLAISFHLS 86
Query: 292 YCLHKGLPFSAFGEMAFLLIQALILVACIYYYSQPVPMTTWVRALLYCAVAPTVLAGQIN 471
Y G PFSA+G+ FL IQ + + + +++ + L+ V VL +
Sbjct: 87 YNFMHGYPFSAWGDSTFLAIQTVTIAVLVLFFNGRKAQSGLF--LVGYVVLMYVLNSGLT 144
Query: 472 P-TLFDALYASQHAIFLFARLPQIWKNFKNKSTGELSFLTFFMNFAGSIVRVFTSIQENA 648
P ++ + + I L +L Q + N++ STG+LS T M FAGS+ R+FTSIQE
Sbjct: 145 PMSVLFTIQSCNIPILLVGKLSQAYTNYQAGSTGQLSAATVIMMFAGSVARIFTSIQETG 204
Query: 649 PVSILTGFALGVFTNGTILSQILLY-HKAAAAKEKKTN*KLERYPKSN 789
I+ F F N IL Q++ Y +K A K K + K + K +
Sbjct: 205 DFMIILTFIASTFANSVILGQLIYYWNKPAGVKVKDSKAKKPKTKKDD 252
>sp|O75352|MPU1_HUMAN Mannose-P-dolichol utilization defect 1 protein OS=Homo
sapiens GN=MPDU1 PE=1 SV=2
Length = 247
Score = 120 bits (299), Expect = 2e-026
Identities = 75/213 (35%), Positives = 113/213 (53%), Gaps = 9/213 (4%)
Frame = +1
Query: 127 CLLPLISKLLGYILVAASITVKLPQIMKIVHHKSVRGLSVVAFELEVVGYTISLAYCLHK 306
CL L+SK LG +VA S+ VKLPQ+ KI+ KS GLS+ + LE+V T ++ Y +
Sbjct: 37 CLKILLSKGLGLGIVAGSLLVKLPQVFKILGAKSAEGLSLQSVMLELVALTGTMVYSITN 96
Query: 307 GLPFSAFGEMAFLLIQALILVACIYYYSQPVPMTTWVRALLYCAVAPTVLAGQINP---- 474
PFS++GE FL++Q + + + +Y V+ + + A VL ++P
Sbjct: 97 NFPFSSWGEALFLMLQTITICFLVMHYRGQT-----VKGVAFLACYGLVLLVLLSPLTPL 151
Query: 475 TLFDALYASQHAIFLFARLPQIWKNFKNKSTGELSFLTFFMNFAGSIVRVFTSIQENAPV 654
T+ L AS + RL Q N+ N TG+LS +T F+ F GS+ R+FTSIQE
Sbjct: 152 TVVTLLQASNVPAVVVGRLLQAATNYHNGHTGQLSAITVFLLFGGSLARIFTSIQETGDP 211
Query: 655 SILTGFALGVFTNGTILSQILLYHKAAAAKEKK 753
+ F + NG I +Q+L Y A ++K
Sbjct: 212 LMAGTFVVSSLCNGLIAAQLLFYWNAKPPHKQK 244
>sp|Q9R0Q9|MPU1_MOUSE Mannose-P-dolichol utilization defect 1 protein OS=Mus
musculus GN=Mpdu1 PE=2 SV=1
Length = 247
Score = 119 bits (298), Expect = 3e-026
Identities = 73/213 (34%), Positives = 113/213 (53%), Gaps = 9/213 (4%)
Frame = +1
Query: 127 CLLPLISKLLGYILVAASITVKLPQIMKIVHHKSVRGLSVVAFELEVVGYTISLAYCLHK 306
CL L+SK LG +VA S+ VKLPQ+ K++ KS GLS+ + LE+V T ++ Y +
Sbjct: 37 CLKILLSKGLGLGIVAGSLLVKLPQVFKLLGAKSAEGLSLQSVMLELVALTGTVVYSITN 96
Query: 307 GLPFSAFGEMAFLLIQALILVACIYYYSQPVPMTTWVRALLYCAVAPTVLAGQINP---- 474
PFS++GE FL +Q + + + +Y V+ + + A VL ++P
Sbjct: 97 NFPFSSWGEALFLTLQTVAICFLVMHYRGET-----VKGVAFLACYAMVLLALLSPLTPL 151
Query: 475 TLFDALYASQHAIFLFARLPQIWKNFKNKSTGELSFLTFFMNFAGSIVRVFTSIQENAPV 654
+ L AS + +L Q N++N TG+LS +T FM F GS+ R+FTS+QE
Sbjct: 152 AVVTLLQASNVPAVVVGKLLQAATNYRNGHTGQLSAITVFMLFGGSLARIFTSVQETGDP 211
Query: 655 SILTGFALGVFTNGTILSQILLYHKAAAAKEKK 753
+ F + NG I +Q+L Y A A ++K
Sbjct: 212 LMAGVFVVSSLCNGLIAAQVLFYWNAKAPHKQK 244
>sp|Q60441|MPU1_CRIGR Mannose-P-dolichol utilization defect 1 protein
OS=Cricetulus griseus GN=MPDU1 PE=2 SV=2
Length = 247
Score = 117 bits (293), Expect = 1e-025
Identities = 75/219 (34%), Positives = 112/219 (51%), Gaps = 9/219 (4%)
Frame = +1
Query: 109 EFPEKDCLLPLISKLLGYILVAASITVKLPQIMKIVHHKSVRGLSVVAFELEVVGYTISL 288
+F CL L+SK LG +VA S+ VKLPQI KI+ KS GLS+ + LE+V T ++
Sbjct: 31 DFLHVPCLKILLSKGLGLGIVAGSLLVKLPQIFKILGAKSAEGLSLQSVMLELVALTGTV 90
Query: 289 AYCLHKGLPFSAFGEMAFLLIQALILVACIYYYSQPVPMTTWVRALLYCAVAPTVLAGQI 468
Y + PFS++GE FL +Q + + + +Y V+ + A T+L +
Sbjct: 91 IYSITNNFPFSSWGEALFLTLQTITICLLVLHYRGDT-----VKGVALLACYATLLLALL 145
Query: 469 NP----TLFDALYASQHAIFLFARLPQIWKNFKNKSTGELSFLTFFMNFAGSIVRVFTSI 636
+P + L AS + +L Q N+ N TG+LS +T FM F GS+ R+FTS+
Sbjct: 146 SPLTPLAVVTMLQASNVPAVVVGKLLQAATNYHNGHTGQLSAITVFMLFGGSLARIFTSV 205
Query: 637 QENAPVSILTGFALGVFTNGTILSQILLYHKAAAAKEKK 753
QE + F + NG I +Q+L Y A + K
Sbjct: 206 QETGDPLMAGVFVVSSLCNGLIAAQVLFYWNAKPPHKHK 244
>sp|Q20157|MPU1_CAEEL Mannose-P-dolichol utilization defect 1 protein homolog
OS=Caenorhabditis elegans GN=F38E1.9 PE=2 SV=1
Length = 238
Score = 114 bits (284), Expect = 1e-024
Identities = 67/227 (29%), Positives = 125/227 (55%), Gaps = 3/227 (1%)
Frame = +1
Query: 79 SCAMGSLRNGEFPEKDCLLPLISKLLGYILVAASITVKLPQIMKIVHHKSVRGLSVVAFE 258
+C L N F C ++S+ LG+ + SI + +PQI+KI +S +G+S +
Sbjct: 12 NCFEELLINFNFFHPTCPKAVLSRGLGFAITLGSILLFVPQILKIQAARSAQGISAASQL 71
Query: 259 LEVVGYTISLAYCLHKGLPFSAFGEMAFLLIQALILVACIYYYSQPVPMTTWVRALLYCA 438
L +VG + +Y G FS +G+ F+ +Q +I++ I+ +S ++ ++ A
Sbjct: 72 LALVGAIGTASYSYRSGFVFSGWGDSFFVAVQLVIIILQIFLFSGQTMLSVGFLGIV-SA 130
Query: 439 VAPTVLAGQINPTLFDALYASQHAIFLFARLPQIWKNFKNKSTGELSFLTFFMNFAGSIV 618
VA V++ I A+ + I + ++L QI +N++ +STG+LS ++ F+ FAG++
Sbjct: 131 VAYGVVSKSIPMQTLTAVQTAGIPIVVVSKLLQISQNYRAQSTGQLSLISVFLQFAGTLA 190
Query: 619 RVFTSIQENAPVSILTGFALGVFTNGTILSQILLY--HKAAAAKEKK 753
RVFTS+Q+ + ++ ++ NG I +Q +Y H +AAK+K+
Sbjct: 191 RVFTSVQDTGDMLLIVSYSTAAVLNGLIFAQFFMYWSHSESAAKKKR 237
>sp|Q8N755|PQLC3_HUMAN PQ-loop repeat-containing protein 3 OS=Homo sapiens
GN=PQLC3 PE=2 SV=1
Length = 202
Score = 68 bits (164), Expect = 9e-011
Identities = 52/195 (26%), Positives = 91/195 (46%), Gaps = 4/195 (2%)
Frame = +1
Query: 151 LLGYILVAASITVKLPQIMKIVHHKSVRGLSVVAFELEVVGYTISLAYCLHKGLPFSAFG 330
L + + +KLPQI ++ +S RGLS+ + LE+ G+ + L Y + G P +
Sbjct: 8 LCNWSTLGVCAALKLPQISAVLAARSARGLSLPSLLLELAGFLVFLRYQCYYGYPPLTYL 67
Query: 331 EMAFLLIQALILVACIYYYSQPVPMTTWVRALLYCAVAPTVLAGQINPTLFDALYASQHA 510
E L+ Q +IL+ CI++++ V T A+L + L I + L A
Sbjct: 68 EYPILIAQDVILLLCIFHFNGNVKQATPYIAVLVSSWFILALQKWIIDLAMN-LCTFISA 126
Query: 511 IFLFARLPQIWKNFKNKSTGELSFLTFFMNFAGSIVRVFTSIQENAPVSILTGFALGVFT 690
FA+L +W K + +G +S LT+ ++ R+ T++ +IL F + +
Sbjct: 127 ASKFAQLQCLW---KTRDSGTVSALTWSLSSYTCATRIITTLMTTNDFTILLRFVIMLAL 183
Query: 691 NGTILSQILLYHKAA 735
N + +L Y K A
Sbjct: 184 NIWVTVTVLRYRKTA 198
>sp|Q8C6U2|PQLC3_MOUSE PQ-loop repeat-containing protein 3 OS=Mus musculus
GN=Pqlc3 PE=2 SV=1
Length = 202
Score = 59 bits (141), Expect = 4e-008
Identities = 46/188 (24%), Positives = 93/188 (49%), Gaps = 14/188 (7%)
Frame = +1
Query: 187 VKLPQIMKIVHHKSVRGLSVVAFELEVVGYTISLAYCLHKGLPFSAFGEMAFLLIQALIL 366
+KLPQI + +S RG+S+ + LE+ G+ + L Y + G P + E L+ Q ++L
Sbjct: 20 LKLPQIYAQLAARSARGISLPSLLLELAGFLVFLRYQHYYGNPLLTYLEYPILIAQDIVL 79
Query: 367 VACIYYYS----QPVP-MTTWVRALLYCAVAPTVLAGQINPTLFDALYASQHAIFLFARL 531
+ +++++ Q +P M +V + ++ ++ +N L A FA+L
Sbjct: 80 LLFVFHFNGNVKQALPYMAVFVSSWFILSLQKWIIDLAMN------LCTVISAASKFAQL 133
Query: 532 PQIWKNFKNKSTGELSFLTFFMNFAGSIVRVFTSIQENAPVSILTGFALGVFTNGTILSQ 711
+W K + +G +S LT+ ++ R+ T++ ++IL F + + N + +
Sbjct: 134 QYLW---KVQDSGAVSALTWGLSAYTCATRIITTLMTTNDLTILIRFVIMLALNIWVTAT 190
Query: 712 ILLYHKAA 735
+L Y K+A
Sbjct: 191 VLHYRKSA 198
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,819,846,109
Number of Sequences: 518415
Number of Extensions: 95819846109
Number of Successful Extensions: 619733697
Number of sequences better than 0.0: 0
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