BLASTX 7.6.2
Query= UN23353 /QuerySize=1328
(1327 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8CGF5|TMM56_MOUSE Transmembrane protein 56 OS=Mus musculus G... 118 1e-025
sp|Q96MV1|TMM56_HUMAN Transmembrane protein 56 OS=Homo sapiens G... 111 1e-023
sp|Q6PGS5|TM56B_XENLA Transmembrane protein 56-B OS=Xenopus laev... 108 1e-022
sp|Q6GLX2|TM56A_XENLA Transmembrane protein 56-A OS=Xenopus laev... 101 1e-020
sp|Q6P4N1|TMM56_XENTR Transmembrane protein 56 OS=Xenopus tropic... 99 8e-020
sp|Q5XIY2|TM56B_DANRE Transmembrane protein 56-B OS=Danio rerio ... 96 4e-019
sp|P47153|YJ86_YEAST Uncharacterized TLC domain-containing prote... 64 2e-009
>sp|Q8CGF5|TMM56_MOUSE Transmembrane protein 56 OS=Mus musculus GN=Tmem56 PE=2
SV=1
Length = 276
Score = 118 bits (295), Expect = 1e-025
Identities = 72/245 (29%), Positives = 133/245 (54%), Gaps = 11/245 (4%)
Frame = -2
Query: 1065 LLASVCSGILMCKIVYDLTGF-ISPLLFSAYGKLDGKVRMEWNNRGFSTFHAVFVSVASI 889
++ +VCS ++ +I++ + S + S Y L ++EWN+R ST H++ V + +
Sbjct: 21 VICTVCSSFVVFQILFHFVSYWFSARVSSGYNSLSIDKKIEWNSRVVSTCHSLLVGIFGL 80
Query: 888 YLLVISDQFDESVHGDSVINSTTRLSESVMGISLGYFVADLMMIFWHFPTLGGVEYVFHH 709
YL FDE+ D + T ++ ++ S GY ++DL++I +++ +G ++ HH
Sbjct: 81 YLFF----FDEATITDPLWGDPTYVNINIATAS-GYLISDLLIILFNWKVIGDKFFIIHH 135
Query: 708 CLSMFSIILSVTSGQAQFYIFMVLLSEATTPFVNLRWYLDA-SGQKGSKAYTLNGIALFL 532
C + + +T+G + LL+E ++PFVN RW+ +A K SKA +NGI + +
Sbjct: 136 CAGLTAYYFVLTTGALAYIANFRLLAELSSPFVNQRWFFEALKYPKFSKANVINGILMTV 195
Query: 531 GWLVARILLF--IYFFVH-MYSHFHQVKQVFPLGFYSLIAVGPVLSAMNLLWFWKITKGL 361
+ + RI+ +YFF++ +Y ++ F + ++ +L MN++W KITKG
Sbjct: 196 VFFIVRIISIPPMYFFLYSVYGTEPYIRFGFVIQSVWIVTC-VILDVMNIMWMIKITKGC 254
Query: 360 IKTIS 346
IK IS
Sbjct: 255 IKVIS 259
>sp|Q96MV1|TMM56_HUMAN Transmembrane protein 56 OS=Homo sapiens GN=TMEM56 PE=1
SV=1
Length = 263
Score = 111 bits (277), Expect = 1e-023
Identities = 72/252 (28%), Positives = 131/252 (51%), Gaps = 11/252 (4%)
Frame = -2
Query: 1068 VLLASVCSGILMCKIV-YDLTGFISPLLFSAYGKLDGKVRMEWNNRGFSTFHAVFVSVAS 892
+L++ C +++ Y ++ + S + + L K ++EWN+R ST H++ V +
Sbjct: 7 LLISVTCISFFTFQLLFYFVSYWFSAKVSPGFNSLSFKKKIEWNSRVVSTCHSLVVGIFG 66
Query: 891 IYLLVISDQFDESVHGDSVINSTTRLSESVMGISLGYFVADLMMIFWHFPTLGGVEYVFH 712
+Y+ + FDE+ D + + L+ + I+ GY ++DL +I ++ +G ++ H
Sbjct: 67 LYIFL----FDEATKADPLWGGPS-LANVNIAIASGYLISDLSIIILYWKVIGDKFFIMH 121
Query: 711 HCLSMFSIILSVTSGQAQFYIFMVLLSEATTPFVNLRWYLDA-SGQKGSKAYTLNGIALF 535
HC S+++ L + +G + LL+E ++PFVN RW+ +A K SKA +NGI +
Sbjct: 122 HCASLYAYYLVLKNGVLAYIGNFRLLAELSSPFVNQRWFFEALKYPKFSKAIVINGILMT 181
Query: 534 LGWLVARILLFIYFFVHMYSHFHQVKQVFPLGF---YSLIAVGPVLSAMNLLWFWKITKG 364
+ + + RI + + MYS + + LG S + VL MN++W KI+KG
Sbjct: 182 VVFFIVRIASMLPHYGFMYS-VYGTEPYIRLGVLIQLSWVISCVVLDVMNVMWMIKISKG 240
Query: 363 LIKTISKATGKK 328
IK IS +K
Sbjct: 241 CIKVISHIRQEK 252
>sp|Q6PGS5|TM56B_XENLA Transmembrane protein 56-B OS=Xenopus laevis GN=tmem56-b
PE=2 SV=1
Length = 262
Score = 108 bits (268), Expect = 1e-022
Identities = 67/250 (26%), Positives = 128/250 (51%), Gaps = 8/250 (3%)
Frame = -2
Query: 1071 LVLLASVCSGILMCKIVYDLTGFISPLLFSAYGKLDGKVRMEWNNRGFSTFHAVFVSVAS 892
L + SV S + + + + ++S L + KL + ++EWN+R S+FHA+ V
Sbjct: 7 LTVFISVTSLAVFQFLFHVGSSWLSTRLTGGFHKLSARQKIEWNSRTVSSFHALVVGCFC 66
Query: 891 IYLLVISDQFDESVHGDSVINSTTRLSESVMGISLGYFVADLMMIFWHFPTLGGVEYVFH 712
+Y+LV +D++V+ D V + +V ++ GY ++DL++I +++ +G +V H
Sbjct: 67 LYILV----YDDAVNADPVWGDPFMVKLNV-AVTSGYLISDLLLIIYYWKEIGDKYFVTH 121
Query: 711 HCLSMFSIILSVTSGQAQFYIFMVLLSEATTPFVNLRWYLDASG-QKGSKAYTLNGIALF 535
H ++++ + G ++ L++E +TPFVN RW+ + G K S +NG+ +
Sbjct: 122 HLAALYACYYVLGEGMLPYFGNFRLIAEFSTPFVNQRWFFEVLGYSKYSLPNMVNGVLMT 181
Query: 534 LGWLVARILLFIYFFVHMYSHF-HQVKQVFPLGFYSLIAVGPV-LSAMNLLWFWKITKGL 361
+ + + RI + ++ ++S F + LG + V L MN++W KI KG
Sbjct: 182 ISFFIVRIAVIPIYYGRVFSTFGTEAFHRLGLGAQCAWIISSVSLDIMNVMWMIKIAKGC 241
Query: 360 IKTISKATGK 331
K + GK
Sbjct: 242 YKVLYHRDGK 251
>sp|Q6GLX2|TM56A_XENLA Transmembrane protein 56-A OS=Xenopus laevis GN=tmem56-a
PE=2 SV=1
Length = 258
Score = 101 bits (251), Expect = 1e-020
Identities = 76/261 (29%), Positives = 124/261 (47%), Gaps = 33/261 (12%)
Frame = -2
Query: 1041 ILMCKIVYDLTGF------ISPLLF----SAYGKLDGKVRMEWNNRGFSTFHAVFVSVAS 892
I C + GF ISP LF S Y +L + EW++R ST HA+ V A
Sbjct: 6 ISYCVVTGSFLGFQLLFSAISPRLFTKYSSTYRQLSFGKQCEWDSRFVSTNHALIVGSAC 65
Query: 891 IYLLVISDQFDESVHGDSVINSTTRLSESVMGISLGYFVADLMMIFWHFPTLGGVEYVFH 712
+Y+L +D++V+ D + + +V I+ GY V DL+++ + + V H
Sbjct: 66 LYILA----YDDAVNADPIWGDPFWVKMNV-AITCGYLVQDLLLLARFWKVMRDPYMVCH 120
Query: 711 HCLSMFSIILSVTSGQAQFYIFMVLLSEATTPFVNLRWYLDASGQ-KGSKAYTLNGIALF 535
H +S + G ++ L+SE +TPFVN RW+ D G+ + S LNG+A+
Sbjct: 121 HLAVFYSYGYVLNRGVLPYFANFRLISELSTPFVNQRWFFDVIGKPRSSWPVLLNGLAMA 180
Query: 534 LGWLVARILLFIYFFVHMYSHFHQVKQVFPLGFYSLIAVGP---------VLSAMNLLWF 382
L + + RI + + S++ QV F Y + +GP VL +N+ W
Sbjct: 181 LVFFIVRIAV-------IPSYYSQVFATFGTEGYIRLGIGPQVAWIVSCVVLDILNVFWM 233
Query: 381 WKITKGLIKTI-SKATGKKKQ 322
+KI +G K + +K GK ++
Sbjct: 234 YKIARGFYKVVKAKPDGKPRR 254
>sp|Q6P4N1|TMM56_XENTR Transmembrane protein 56 OS=Xenopus tropicalis GN=tmem56
PE=2 SV=1
Length = 259
Score = 99 bits (244), Expect = 8e-020
Identities = 72/246 (29%), Positives = 118/246 (47%), Gaps = 27/246 (10%)
Frame = -2
Query: 1014 LTGFISPLLF----SAYGKLDGKVRMEWNNRGFSTFHAVFVSVASIYLLVISDQFDESVH 847
L ISP F S Y +L + EW++R ST HA+ V +Y+L +DE+V+
Sbjct: 22 LFSIISPRTFTKYSSTYRQLSFGKQCEWDSRCVSTTHALVVGSGCLYILA----YDEAVN 77
Query: 846 GDSVINSTTRLSESVMGISLGYFVADLMMIFWHFPTLGGVEYVFHHCLSMFSIILSVTSG 667
D + + +V I+ GY V DL+++ + + V HH +S + G
Sbjct: 78 ADPIWGDPFWVKMNV-AITCGYLVHDLLLLARFWKVMRDPYMVCHHLAVFYSYGYVLNRG 136
Query: 666 QAQFYIFMVLLSEATTPFVNLRWYLDASGQ-KGSKAYTLNGIALFLGWLVARILLFIYFF 490
++ L+SE +TPFVN RW+ D G+ + S LNG+A+ L + + RI +
Sbjct: 137 VLPYFANFRLISELSTPFVNQRWFFDVIGKPRSSWPVLLNGLAMALVFFIVRIAV----- 191
Query: 489 VHMYSHFHQVKQVFPLGFYSLIAVGP---------VLSAMNLLWFWKITKGLIKTI-SKA 340
+ S++ QV F Y + +GP VL +N+ W +KI +G K + +K
Sbjct: 192 --IPSYYSQVFATFGTEGYIRLGIGPQVAWIVSCVVLDILNVFWMYKIARGFYKVVKAKP 249
Query: 339 TGKKKQ 322
GK ++
Sbjct: 250 DGKPRR 255
>sp|Q5XIY2|TM56B_DANRE Transmembrane protein 56-B OS=Danio rerio GN=tmem56b PE=2
SV=1
Length = 264
Score = 96 bits (238), Expect = 4e-019
Identities = 67/233 (28%), Positives = 120/233 (51%), Gaps = 15/233 (6%)
Frame = -2
Query: 1002 ISPLLFS----AYGKLDGKVRMEWNNRGFSTFHAVFVSVASIYLLVISDQFDESVHGDSV 835
+SP+L S YGKL +WN+R ST HA+ V + +Y+L +D++V+ D V
Sbjct: 23 VSPVLSSNFTQGYGKLPPNKLNDWNSRLVSTVHALIVGLFCLYIL----WYDDAVNEDPV 78
Query: 834 INSTTRLSESVMGISLGYFVADLMMIFWHFPTLGGVEYVFHHCLSMFSIILSVTSGQAQF 655
+ +V I+ GY DL+++ ++ T+G V +V HH ++++ +T G +
Sbjct: 79 WGDPNLVKLNV-AITCGYLFYDLLLLACNWSTMGDVFFVCHHLAALYAYGYVLTRGVLPY 137
Query: 654 YIFMVLLSEATTPFVNLRWYLDA-SGQKGSKAYTLNGIALFLGWLVARILLFIYFFVHMY 478
+ L+SE +TPFVN RW+ +A + + + NGIA+ + + + RI + ++ ++
Sbjct: 138 FANFRLISELSTPFVNQRWFFEALAYPRTHQLVVANGIAMAVVFFLVRIAVMPPYWAKVF 197
Query: 477 SHFHQ-VKQVFPLGFYSLIAVGPV-LSAMNLLWFWKITKGLIKTISKATGKKK 325
+ + L + V L +N++W +KI +G K I TGK K
Sbjct: 198 GIIYSPTFEKLGLAIQVAWIISCVCLDILNIIWMYKIARGCYKVI---TGKLK 247
>sp|P47153|YJ86_YEAST Uncharacterized TLC domain-containing protein YJR116W
OS=Saccharomyces cerevisiae GN=YJR116W PE=1 SV=1
Length = 279
Score = 64 bits (155), Expect = 2e-009
Identities = 48/178 (26%), Positives = 87/178 (48%), Gaps = 9/178 (5%)
Frame = -2
Query: 840 SVINSTTRLSESVMGISLGYFVADLMMIFWHFPTLGGVEYVFHHCLSMFSIILSVTSGQA 661
+V+ T S V +S GYF+ DL M +F L G+E+ H S++ ++LS+
Sbjct: 103 NVVTYTDSYSSMVSSLSAGYFIWDLTMCVRYF-KLYGLEFTGHAIGSVYVMLLSLRP-FC 160
Query: 660 QFYIFMVLLSEATTPFVNLRWYLDASGQKGSKAYTL-----NGIALFLGWLVARILLFIY 496
Q +I L+ EA+TPFVN+ W++ K + L NG+ L + V RI
Sbjct: 161 QPWIGRFLIYEASTPFVNINWFIMQCNAKSKNSIPLWFNVVNGLLLMTVFFVVRICWGSI 220
Query: 495 FFVHMYSHFHQVKQVFP-LGFYSLIAVGPVLSAMNLLWFWKITKGLIKTISKATGKKK 325
++ +V+ P +++++ ++ +N+LWF K+ + + K ++K K
Sbjct: 221 ASALLFRQMWKVRDELPKFSAVTMMSLNIFMNLLNVLWFKKMIR-IAKKLAKPAPTSK 277
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,767,994,010
Number of Sequences: 518415
Number of Extensions: 98767994010
Number of Successful Extensions: 632508636
Number of sequences better than 0.0: 0
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