BLASTX 7.6.2
Query= UN23398 /QuerySize=2333
(2332 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P04844|RPN2_HUMAN Dolichyl-diphosphooligosaccharide--protein ... 137 4e-031
sp|Q9DBG6|RPN2_MOUSE Dolichyl-diphosphooligosaccharide--protein ... 134 5e-030
sp|Q5RBM1|RPN2_PONAB Dolichyl-diphosphooligosaccharide--protein ... 133 8e-030
sp|Q3SZI6|RPN2_BOVIN Dolichyl-diphosphooligosaccharide--protein ... 132 2e-029
sp|P25235|RPN2_RAT Dolichyl-diphosphooligosaccharide--protein gl... 132 2e-029
sp|Q9GL01|RPN2_PIG Dolichyl-diphosphooligosaccharide--protein gl... 121 4e-026
>sp|P04844|RPN2_HUMAN Dolichyl-diphosphooligosaccharide--protein
glycosyltransferase subunit 2 OS=Homo sapiens GN=RPN2 PE=1 SV=3
Length = 631
Score = 137 bits (344), Expect = 4e-031
Identities = 110/439 (25%), Positives = 193/439 (43%), Gaps = 22/439 (5%)
Frame = +1
Query: 811 EGPISTTASVIRGLTSLAASDSTGLNLPGDKIVGLAKFFLGVGIPGDAKDFFNQIDALAC 990
E + TTA + L T ++ D+++ L + F+ A A
Sbjct: 202 EEGLETTALFVAATYKLMDHVGTEPSIKEDQVIQLMNAIFSKKNFESLSEAFSVASAAAV 261
Query: 991 LEDNRFSVPLILSLPSTVISLTKKEPLKVKVGTVLGSKAPALSVKLVQALSSGSKGSSVI 1170
L NR+ VP+++ + ++ L+++V VL +VKL A S S+ + +
Sbjct: 262 LSHNRYHVPVVVVPEGSASDTHEQAILRLQVTNVLSQPLTQATVKLEHAKSVASRATVL- 320
Query: 1171 NNQELKFDAVSATYFLDSFPKNFDVGKYTFVFEILLDESANEKAYVTEAQTKVPVAATGA 1350
Q+ F V + L+ F G Y F+ E+ + Y+ ++ V +
Sbjct: 321 --QKTSFTPVGDVFELNFMNVKFSSGYYDFLVEV-----EGDNRYIANT-VELRVKISTE 372
Query: 1351 ITIEDAEIAVLDSDVGSVESQKKLDLTKDGAVSLSANHLQKLRLSLQLT-TPLGHVFKPH 1527
+ I + +++ +D D ++ + A+ Q L QL G PH
Sbjct: 373 VGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPH 432
Query: 1528 QAFLKLKHESQVEHIFLVKTSGKKSELVLDFLGLVEKLYY--LSGKYEIQLTIGDASMEN 1701
Q F++L ++ + + V K+ + K+ + SG Y + L IGDA+++N
Sbjct: 433 QTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKN 492
Query: 1702 SLLSNIGHIELDLPQRPEKAASPPLQPTDPYSRYGPKAEISHIFRVPEKLPAKQLSLIFL 1881
+L N+ + + P+ E+A S L + + PK EI H+FR PEK P +S F
Sbjct: 493 PILWNVADVVIKFPE--EEAPSTVLS----QNLFTPKQEIQHLFREPEKRPPTVVSNTFT 546
Query: 1882 GLIVLPFIGFLIGLTRLGVNIKSFPSSVGAATSALLFHGGIGAVLLLYVLFWVKLDLFTT 2061
LI+ P + R+G N+ +F A S ++FH G A+L L ++W +L++F T
Sbjct: 547 ALILSPLLLLFALWIRIGANVSNFT----FAPSTIIFHLGHAAMLGLMYVYWTQLNMFQT 602
Query: 2062 LKALSLLGVFLLFVGHRTL 2118
LK L++LG G+R L
Sbjct: 603 LKYLAILGSVTFLAGNRML 621
>sp|Q9DBG6|RPN2_MOUSE Dolichyl-diphosphooligosaccharide--protein
glycosyltransferase subunit 2 OS=Mus musculus GN=Rpn2 PE=2 SV=1
Length = 631
Score = 134 bits (335), Expect = 5e-030
Identities = 108/439 (24%), Positives = 194/439 (44%), Gaps = 22/439 (5%)
Frame = +1
Query: 811 EGPISTTASVIRGLTSLAASDSTGLNLPGDKIVGLAKFFLGVGIPGDAKDFFNQIDALAC 990
E + TA + L T ++ D+++ L + F+ A A
Sbjct: 202 EEGLELTALFVAATYKLMDHVGTEPSMKEDQVIQLMNTIFSKKNFESLSEAFSVASAAAA 261
Query: 991 LEDNRFSVPLILSLPSTVISLTKKEPLKVKVGTVLGSKAPALSVKLVQALSSGSKGSSVI 1170
L NR+ VP+++ + ++ L+++V VL +VKL A S+ ++ + +
Sbjct: 262 LSQNRYHVPVVVVPEGSTSDTQEQAILRLQVSNVLSQPLAQAAVKLEHAKSAATRATVL- 320
Query: 1171 NNQELKFDAVSATYFLDSFPKNFDVGKYTFVFEILLDESANEKAYVTEAQTKVPVAATGA 1350
Q+ F V + L+ KN + + F + ++ + A E + K+ +
Sbjct: 321 --QKTPFSLVGNVFELNF--KNVKLSSGYYDFSVRVEGDSRYIANTVELRVKI----STE 372
Query: 1351 ITIEDAEIAVLDSDVGSVESQKKLDLTKDGAVSLSANHLQKLRLSLQLT-TPLGHVFKPH 1527
+ I + +++ +D D ++ + A+ Q L QL G PH
Sbjct: 373 VGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPH 432
Query: 1528 QAFLKLKHESQVEHIFLVKTSGKKSELVLDFLGLVEKLYY--LSGKYEIQLTIGDASMEN 1701
Q F++L ++ + + V K+ + K+ + SG Y + L IGDA+++N
Sbjct: 433 QTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKN 492
Query: 1702 SLLSNIGHIELDLPQRPEKAASPPLQPTDPYSRYGPKAEISHIFRVPEKLPAKQLSLIFL 1881
+L N+ + + P+ E+A S L S + PK EI H+FR PEK P +S F
Sbjct: 493 PILWNVADVVIKFPE--EEAPSTVLS----QSLFTPKQEIQHLFREPEKRPPTVVSNTFT 546
Query: 1882 GLIVLPFIGFLIGLTRLGVNIKSFPSSVGAATSALLFHGGIGAVLLLYVLFWVKLDLFTT 2061
LI+ P + R+G N+ +F A S ++FH G A+L L ++W +L++F T
Sbjct: 547 ALILSPLLLLFALWIRIGANVSNFT----FAPSTVIFHLGHAAMLGLMYIYWTQLNMFQT 602
Query: 2062 LKALSLLGVFLLFVGHRTL 2118
LK L++LG G+R L
Sbjct: 603 LKYLAVLGTVTFLAGNRML 621
>sp|Q5RBM1|RPN2_PONAB Dolichyl-diphosphooligosaccharide--protein
glycosyltransferase subunit 2 OS=Pongo abelii GN=RPN2 PE=2 SV=1
Length = 631
Score = 133 bits (333), Expect = 8e-030
Identities = 107/439 (24%), Positives = 192/439 (43%), Gaps = 22/439 (5%)
Frame = +1
Query: 811 EGPISTTASVIRGLTSLAASDSTGLNLPGDKIVGLAKFFLGVGIPGDAKDFFNQIDALAC 990
E + TTA + L T ++ D+++ L + F+ A
Sbjct: 202 EEGLETTALFVAATYKLMDHVGTEPSIKEDQVIQLMNAIFSKKNFESLSEAFSVASVAAV 261
Query: 991 LEDNRFSVPLILSLPSTVISLTKKEPLKVKVGTVLGSKAPALSVKLVQALSSGSKGSSVI 1170
L NR+ VP+++ + ++ L+++V VL +VKL A S S+ + +
Sbjct: 262 LSHNRYHVPVVVVPEGSASDTHEQAILRLQVTNVLSQPLTQATVKLEHAKSVASRATVL- 320
Query: 1171 NNQELKFDAVSATYFLDSFPKNFDVGKYTFVFEILLDESANEKAYVTEAQTKVPVAATGA 1350
Q+ F V + L+ F G Y F+ ++ + Y+ ++ V +
Sbjct: 321 --QKTSFTPVGDVFELNFMNVKFSSGYYDFLVKV-----EGDNRYIANT-VELRVKISTE 372
Query: 1351 ITIEDAEIAVLDSDVGSVESQKKLDLTKDGAVSLSANHLQKLRLSLQLT-TPLGHVFKPH 1527
+ I + +++ +D D ++ + A+ Q L QL G PH
Sbjct: 373 VGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPH 432
Query: 1528 QAFLKLKHESQVEHIFLVKTSGKKSELVLDFLGLVEKLYY--LSGKYEIQLTIGDASMEN 1701
Q F++L ++ + + V K+ + K+ + SG Y + L IGDA+++N
Sbjct: 433 QTFVRLHNQKTGQEVVFVAEPDSKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKN 492
Query: 1702 SLLSNIGHIELDLPQRPEKAASPPLQPTDPYSRYGPKAEISHIFRVPEKLPAKQLSLIFL 1881
+L N+ + + P+ E+A S L + + PK EI H+FR PEK P +S F
Sbjct: 493 PILWNVADVVIKFPE--EEAPSTVLS----QNLFTPKQEIQHLFREPEKRPPTVVSNTFT 546
Query: 1882 GLIVLPFIGFLIGLTRLGVNIKSFPSSVGAATSALLFHGGIGAVLLLYVLFWVKLDLFTT 2061
LI+ P + R+G N+ +F + S ++FH G A+L L ++W +L++F T
Sbjct: 547 ALILSPLLLLFALWIRIGANVSNFTFT----PSTIIFHLGHAAMLGLMYVYWTQLNMFQT 602
Query: 2062 LKALSLLGVFLLFVGHRTL 2118
LK L++LG G+R L
Sbjct: 603 LKYLAILGSVTFLAGNRML 621
>sp|Q3SZI6|RPN2_BOVIN Dolichyl-diphosphooligosaccharide--protein
glycosyltransferase subunit 2 OS=Bos taurus GN=RPN2 PE=2 SV=1
Length = 631
Score = 132 bits (330), Expect = 2e-029
Identities = 110/440 (25%), Positives = 195/440 (44%), Gaps = 24/440 (5%)
Frame = +1
Query: 811 EGPISTTASVIRGLTSLAASDSTGLNLPGDKIVGLAKFFLGVGIPGDAKDFFNQIDALAC 990
E + TTA + L T ++ D+++ L + F+ A A
Sbjct: 202 EEGLETTALFVAATYKLMDHVGTEPSIKEDQVIQLMNAIFSKKNFESLSEAFSVASAAAA 261
Query: 991 LEDNRFSVPLILSLPSTVISLTKKEP-LKVKVGTVLGSKAPALSVKLVQALSSGSKGSSV 1167
L +NR+ VP+++ +P S T+++ L+++V VL +VKL A S S+ + +
Sbjct: 262 LSENRYHVPVVV-VPEGSPSYTQEQAILRLQVTNVLSQPLTQATVKLEHAKSVASRATVL 320
Query: 1168 INNQELKFDAVSATYFLDSFPKNFDVGKYTFVFEILLDESANEKAYVTEAQTKVPVAATG 1347
Q+ F + + L+ F G Y F ++ + Y+ ++ V +
Sbjct: 321 ---QKTSFTLIGDVFELNFMNVKFSSGYYDFSVKV-----EGDNRYIANT-VELRVKIST 371
Query: 1348 AITIEDAEIAVLDSDVGSVESQKKLDLTKDGAVSLSANHLQKLRLSLQLT-TPLGHVFKP 1524
+ I + +++ +D D ++ + A+ Q L QL G P
Sbjct: 372 EVGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTP 431
Query: 1525 HQAFLKLKHESQVEHIFLVKTSGKKSELVLDFLGLVEKLYY--LSGKYEIQLTIGDASME 1698
HQ F++L ++ + + V K+ + KL + SG Y + L IGDA+++
Sbjct: 432 HQTFVRLHNQKTGQEVVFVAEPDSKNVYKFELDTSERKLEFDSASGTYTLYLIIGDATLK 491
Query: 1699 NSLLSNIGHIELDLPQRPEKAASPPLQPTDPYSRYGPKAEISHIFRVPEKLPAKQLSLIF 1878
N +L N+ + + P+ + S L + + PK EI H+FR PEK P +S F
Sbjct: 492 NPILWNVADVVIRFPE--DDVPSTVLSK----NIFTPKQEIQHLFREPEKRPPTVVSNTF 545
Query: 1879 LGLIVLPFIGFLIGLTRLGVNIKSFPSSVGAATSALLFHGGIGAVLLLYVLFWVKLDLFT 2058
LI+ P + R+G N+ +F A S ++FH G A+L L ++W +L++F
Sbjct: 546 TALILSPLLLLFALWIRIGANVSNFT----FAPSTIVFHLGHAAMLGLMYVYWTQLNMFQ 601
Query: 2059 TLKALSLLGVFLLFVGHRTL 2118
TLK L++LG G+R L
Sbjct: 602 TLKYLAILGSVTFLAGNRML 621
>sp|P25235|RPN2_RAT Dolichyl-diphosphooligosaccharide--protein
glycosyltransferase subunit 2 OS=Rattus norvegicus GN=Rpn2 PE=2 SV=2
Length = 631
Score = 132 bits (330), Expect = 2e-029
Identities = 108/439 (24%), Positives = 194/439 (44%), Gaps = 22/439 (5%)
Frame = +1
Query: 811 EGPISTTASVIRGLTSLAASDSTGLNLPGDKIVGLAKFFLGVGIPGDAKDFFNQIDALAC 990
E + TA + L T ++ D+++ L + F+ A A
Sbjct: 202 EEGLELTALFVAATYKLMDHVGTEPSIKEDQVIQLMNTIFSKKNFESLSEAFSVASAAAA 261
Query: 991 LEDNRFSVPLILSLPSTVISLTKKEPLKVKVGTVLGSKAPALSVKLVQALSSGSKGSSVI 1170
L NR+ VP+++ + ++ L+++V +VL +VKL A S S+ + +
Sbjct: 262 LSQNRYHVPVVVVPEGSASDTQEQAILRLQVSSVLSQPLAQAAVKLEHAKSVASRATVL- 320
Query: 1171 NNQELKFDAVSATYFLDSFPKNFDVGKYTFVFEILLDESANEKAYVTEAQTKVPVAATGA 1350
Q++ F V + L+ KN + + F + ++ A E + K+ +
Sbjct: 321 --QKMPFSLVGDVFELNF--KNVKLPSGYYDFSVRVEGDNRYIANTVELRVKI----STE 372
Query: 1351 ITIEDAEIAVLDSDVGSVESQKKLDLTKDGAVSLSANHLQKLRLSLQLT-TPLGHVFKPH 1527
+ I + +++ +D D ++ + A+ Q L QL G PH
Sbjct: 373 VGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGTFIADSHQNFALFFQLVDVNTGAELTPH 432
Query: 1528 QAFLKLKHESQVEHIFLVKTSGKKSELVLDFLGLVEKLYY--LSGKYEIQLTIGDASMEN 1701
Q F++L ++ + + V K+ + K+ + SG Y + L IGDA+++N
Sbjct: 433 QTFVRLHNQKTGQEVVFVAEPDNKNVYKFELDTSERKIEFDSASGTYTLYLIIGDATLKN 492
Query: 1702 SLLSNIGHIELDLPQRPEKAASPPLQPTDPYSRYGPKAEISHIFRVPEKLPAKQLSLIFL 1881
+L N+ + + P+ E+A S L + + PK EI H+FR PEK P +S F
Sbjct: 493 PILWNVADVVIKFPE--EEAPSTVLS----QNLFTPKQEIQHLFREPEKRPPTVVSNTFT 546
Query: 1882 GLIVLPFIGFLIGLTRLGVNIKSFPSSVGAATSALLFHGGIGAVLLLYVLFWVKLDLFTT 2061
LI+ P + R+G N+ +F A S ++FH G A+L L ++W +L++F T
Sbjct: 547 ALILSPLLLLFALWIRIGANVSNFT----FAPSTVIFHLGHAAMLGLMYVYWTQLNMFQT 602
Query: 2062 LKALSLLGVFLLFVGHRTL 2118
LK L++LG G+R L
Sbjct: 603 LKYLAVLGTVTFLAGNRML 621
>sp|Q9GL01|RPN2_PIG Dolichyl-diphosphooligosaccharide--protein
glycosyltransferase subunit 2 OS=Sus scrofa GN=RPN2 PE=2 SV=1
Length = 629
Score = 121 bits (301), Expect = 4e-026
Identities = 103/436 (23%), Positives = 186/436 (42%), Gaps = 25/436 (5%)
Frame = +1
Query: 811 EGPISTTASVIRGLTSLAASDSTGLNLPGDKIVGLAKFFLGVGIPGDAKDFFNQIDALAC 990
EG + TTA + L + T ++ D+++ L + F+ A A
Sbjct: 203 EGLLETTALFVAATYKLMDHEGTEPSIKEDQVIQLMNTIFSKKNFESLPEAFSVASAAAA 262
Query: 991 LEDNRFSVPLILSLPSTVISLTKKEPLKVKVGTVLGSKAPALSVKLVQALSSGSKGSSVI 1170
L NR+ VP+++ + ++ L+++V VL +VKL A S S+ + +
Sbjct: 263 LSQNRYHVPVVVVPEGSPSDTQEQAFLRLQVTNVLSQPLTQATVKLEHAKSVASRATVL- 321
Query: 1171 NNQELKFDAVSATYFLDSFPKNFDVGKYTFVFEILLDESANEKAYVTEAQTKVPVAATGA 1350
Q+ F V + L+ F G Y F ++ + Y+ ++ V +
Sbjct: 322 --QKTSFTPVGDVFELNFVNVKFSSGYYDFSVKV-----EGDNRYIANT-VELRVKISTE 373
Query: 1351 ITIEDAEIAVLDSDVGSVESQKKLDLTKDGAVSLSANHLQKLRLSLQLT-TPLGHVFKPH 1527
+ I + +++ +D D ++ A+ Q L QL G PH
Sbjct: 374 VGITNVDLSTVDKDQSIAPKTTRVTYPAKAKGPFIADSPQNFALFFQLVDVNTGAELTPH 433
Query: 1528 QAFLKLKHESQVEHIFLVKTSGKKSELVLDFLGLVEKLYY--LSGKYEIQLTIGDASMEN 1701
Q F++L ++ + + V K+ + K+ + SG Y + L IGDA+++N
Sbjct: 434 QTFVRLHNQKTGQEVVFVAEPDSKNVYRFELDTSERKIEFDSASGTYTLYLIIGDATLKN 493
Query: 1702 SLLSNIGHIELDLPQRPEKAASPPLQPTDPYSRYGPKAEISHIFRVPEKLPAKQLSLIFL 1881
+ N+ + + P+ E A S L + + K EI H+FR PEK P +S F
Sbjct: 494 PIHWNVADVVIRFPE--EDAPSTVLSK----NLFTAKQEIQHLFRDPEKRPPTVVSNTFT 547
Query: 1882 GLIVLPFIGFLIGLTRLGVNIKSFPSSVGAATSALLFHGGIGAVLLLYVLFWVKLDLFTT 2061
GLI+ P + R+G I +F + ++FH +G +L ++W +L++F T
Sbjct: 548 GLILSPLLLLFALWIRIGAKISNFTFGL-----TIIFH--LGHAMLAMYVYWTQLNMFQT 600
Query: 2062 LKALSLLGVFLLFVGH 2109
LK L++LG G+
Sbjct: 601 LKYLAILGSVTFLAGN 616
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,767,994,010
Number of Sequences: 518415
Number of Extensions: 98767994010
Number of Successful Extensions: 632508636
Number of sequences better than 0.0: 0
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