BLASTX 7.6.2
Query= UN23399 /QuerySize=1136
(1135 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9M8S8|VTC4_ARATH Inositol-phosphate phosphatase OS=Arabidops... 502 3e-141
sp|P54928|IMP3_SOLLC Inositol monophosphatase 3 OS=Solanum lycop... 424 7e-118
sp|P54926|IMP1_SOLLC Inositol monophosphatase 1 OS=Solanum lycop... 419 3e-116
sp|O49071|IMPP_MESCR Inositol monophosphatase OS=Mesembryanthemu... 411 5e-114
sp|P54927|IMP2_SOLLC Inositol monophosphatase 2 OS=Solanum lycop... 391 8e-108
sp|Q54U72|IMPA1_DICDI Inositol monophosphatase OS=Dictyostelium ... 221 9e-057
sp|Q8CIN7|IMPA2_RAT Inositol monophosphatase 2 OS=Rattus norvegi... 215 6e-055
sp|O14732|IMPA2_HUMAN Inositol monophosphatase 2 OS=Homo sapiens... 214 1e-054
sp|Q91UZ5|IMPA2_MOUSE Inositol monophosphatase 2 OS=Mus musculus... 212 5e-054
sp|P20456|IMPA1_BOVIN Inositol monophosphatase 1 OS=Bos taurus G... 207 2e-052
sp|O77591|IMPA1_PIG Inositol monophosphatase 1 OS=Sus scrofa GN=... 203 2e-051
sp|P97697|IMPA1_RAT Inositol monophosphatase 1 OS=Rattus norvegi... 200 2e-050
sp|P29219|IMPA1_XENLA Inositol monophosphatase 1 OS=Xenopus laev... 197 2e-049
sp|P29218|IMPA1_HUMAN Inositol monophosphatase 1 OS=Homo sapiens... 196 4e-049
sp|O55023|IMPA1_MOUSE Inositol monophosphatase 1 OS=Mus musculus... 196 4e-049
sp|Q5R4X0|IMPA1_PONAB Inositol monophosphatase 1 OS=Pongo abelii... 196 4e-049
sp|P74158|SUHB_SYNY3 Inositol-1-monophosphatase OS=Synechocystis... 182 4e-045
sp|Q19420|IMPA1_CAEEL Inositol monophosphatase ttx-7 OS=Caenorha... 179 5e-044
sp|Q9CNV8|SUHB_PASMU Inositol-1-monophosphatase OS=Pasteurella m... 163 4e-039
sp|Q05533|INM2_YEAST Inositol monophosphatase 2 OS=Saccharomyces... 161 1e-038
>sp|Q9M8S8|VTC4_ARATH Inositol-phosphate phosphatase OS=Arabidopsis thaliana
GN=VTC4 PE=1 SV=1
Length = 271
Score = 502 bits (1291), Expect = 3e-141
Identities = 248/269 (92%), Positives = 259/269 (96%)
Frame = +3
Query: 165 MAENGSLDQFLSAAVDAAQKAGQVIRKGFYETKHVEHKGQVDLVTETDKGCEELVFNHLK 344
MA+N SLDQFL+AA+DAA+KAGQ+IRKGFYETKHVEHKGQVDLVTETDKGCEELVFNHLK
Sbjct: 1 MADNDSLDQFLAAAIDAAKKAGQIIRKGFYETKHVEHKGQVDLVTETDKGCEELVFNHLK 60
Query: 345 HLFPNHKFIGEETTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVV 524
LFPNHKFIGEETTAA GVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVV
Sbjct: 61 QLFPNHKFIGEETTAAFGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVV 120
Query: 525 GVVYNPIMDELFTGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDDATNRI 704
GVVYNPIM+ELFTGVQGKGAFLNGK IKVS QSEL+TALL+ EAGTKRDKATLDD TNRI
Sbjct: 121 GVVYNPIMEELFTGVQGKGAFLNGKRIKVSAQSELLTALLVTEAGTKRDKATLDDTTNRI 180
Query: 705 NSLLTKVRSLRMGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPS 884
NSLLTKVRSLRM GSCALDLCGVACGR DIFYE+GFGGPWDIAAGIVIV+EAGGLIFDPS
Sbjct: 181 NSLLTKVRSLRMSGSCALDLCGVACGRVDIFYELGFGGPWDIAAGIVIVKEAGGLIFDPS 240
Query: 885 GKELDITSQRIAASNASLKELFVEALRLT 971
GK+LDITSQRIAASNASLKELF EALRLT
Sbjct: 241 GKDLDITSQRIAASNASLKELFAEALRLT 269
>sp|P54928|IMP3_SOLLC Inositol monophosphatase 3 OS=Solanum lycopersicum GN=IMP3
PE=2 SV=1
Length = 268
Score = 424 bits (1089), Expect = 7e-118
Identities = 202/266 (75%), Positives = 232/266 (87%)
Frame = +3
Query: 165 MAENGSLDQFLSAAVDAAQKAGQVIRKGFYETKHVEHKGQVDLVTETDKGCEELVFNHLK 344
MA+NGS++QFL AV+AA+KAG++IR+GFY+TKHVEHKG VDLVTETDK CE+ +FNHLK
Sbjct: 1 MAQNGSVEQFLDVAVEAAKKAGEIIREGFYKTKHVEHKGMVDLVTETDKACEDFIFNHLK 60
Query: 345 HLFPNHKFIGEETTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVV 524
FP+HKFIGEETTAA G ELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTI K P V
Sbjct: 61 QRFPSHKFIGEETTAACGNFELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIEKKPTV 120
Query: 525 GVVYNPIMDELFTGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDDATNRI 704
GVVYNPI+DELFTG+ GKGAFLNGKPIKVS+QSELV ALL EAGT RDK +D T RI
Sbjct: 121 GVVYNPIIDELFTGIDGKGAFLNGKPIKVSSQSELVKALLATEAGTNRDKLVVDATTGRI 180
Query: 705 NSLLTKVRSLRMGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPS 884
NSLL KVRSLRM GSCAL+LCGVACGR D+FYE+ FGGPWD+A G VIV+EAGG +FDPS
Sbjct: 181 NSLLFKVRSLRMCGSCALNLCGVACGRLDLFYELEFGGPWDVAGGAVIVKEAGGFVFDPS 240
Query: 885 GKELDITSQRIAASNASLKELFVEAL 962
G E D+T++R+AA+NA LK+ F++AL
Sbjct: 241 GSEFDLTARRVAATNAHLKDAFIKAL 266
>sp|P54926|IMP1_SOLLC Inositol monophosphatase 1 OS=Solanum lycopersicum GN=IMP1
PE=2 SV=1
Length = 273
Score = 419 bits (1075), Expect = 3e-116
Identities = 200/269 (74%), Positives = 234/269 (86%)
Frame = +3
Query: 165 MAENGSLDQFLSAAVDAAQKAGQVIRKGFYETKHVEHKGQVDLVTETDKGCEELVFNHLK 344
MA NGSL++FL AVDAA++AG++IRKGF+ETKHV HKGQVDLVTETDK CE+L+FNHLK
Sbjct: 1 MARNGSLEEFLGVAVDAAKRAGEIIRKGFHETKHVVHKGQVDLVTETDKACEDLIFNHLK 60
Query: 345 HLFPNHKFIGEETTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVV 524
FP+HKFIGEET+AA G +LTDEPTWIVDP+DGTTNFVHGFP VCVSIGLTIGK+P V
Sbjct: 61 QHFPSHKFIGEETSAATGDFDLTDEPTWIVDPVDGTTNFVHGFPSVCVSIGLTIGKIPTV 120
Query: 525 GVVYNPIMDELFTGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDDATNRI 704
GVVY+PI+DELFTG+ GKGA+LNGKPIKVS+QSELV +LL E GT RD T++ T RI
Sbjct: 121 GVVYDPIIDELFTGINGKGAYLNGKPIKVSSQSELVKSLLGTEVGTTRDNLTVETTTRRI 180
Query: 705 NSLLTKVRSLRMGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPS 884
N+LL KVRSLRM GSCALDLC VACGR ++FY IG+GGPWD+A G VIV+EAGG++FDPS
Sbjct: 181 NNLLFKVRSLRMCGSCALDLCWVACGRLELFYLIGYGGPWDVAGGAVIVKEAGGVLFDPS 240
Query: 885 GKELDITSQRIAASNASLKELFVEALRLT 971
G E DITSQR+AA+N LKE FVEAL+L+
Sbjct: 241 GSEFDITSQRVAATNPHLKEAFVEALQLS 269
>sp|O49071|IMPP_MESCR Inositol monophosphatase OS=Mesembryanthemum crystallinum
GN=IMP1 PE=2 SV=1
Length = 270
Score = 411 bits (1056), Expect = 5e-114
Identities = 199/267 (74%), Positives = 226/267 (84%)
Frame = +3
Query: 165 MAENGSLDQFLSAAVDAAQKAGQVIRKGFYETKHVEHKGQVDLVTETDKGCEELVFNHLK 344
MA N L FL+ AVDAA++AG+VIRKGFY K+VEHKGQVDLVTETDK CE+++FN LK
Sbjct: 1 MAANVPLSDFLATAVDAAKRAGEVIRKGFYVKKNVEHKGQVDLVTETDKSCEDIIFNCLK 60
Query: 345 HLFPNHKFIGEETTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVV 524
+PNHKFIGEETTAA G TELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVP V
Sbjct: 61 QQYPNHKFIGEETTAAYGATELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPTV 120
Query: 525 GVVYNPIMDELFTGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDDATNRI 704
GVVYNPIM+ELFTGV+ +GAFLNG PI VS++ ELV LL+ E GTKRDK+T+D TNRI
Sbjct: 121 GVVYNPIMNELFTGVRRQGAFLNGVPIHVSSKDELVNCLLVTEVGTKRDKSTVDATTNRI 180
Query: 705 NSLLTKVRSLRMGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPS 884
N LL KVRS+RM GSCALDLCG+ACGR D+ YE G+GG WD+ AGIVIV EAGG+IFDPS
Sbjct: 181 NGLLFKVRSIRMAGSCALDLCGIACGRADLMYENGYGGAWDVTAGIVIVEEAGGVIFDPS 240
Query: 885 GKELDITSQRIAASNASLKELFVEALR 965
GK+ DIT RIAASN +K+ FVEA +
Sbjct: 241 GKDFDITVTRIAASNPLIKDSFVEAFK 267
>sp|P54927|IMP2_SOLLC Inositol monophosphatase 2 OS=Solanum lycopersicum GN=IMP2
PE=2 SV=1
Length = 265
Score = 391 bits (1002), Expect = 8e-108
Identities = 185/261 (70%), Positives = 223/261 (85%), Gaps = 1/261 (0%)
Frame = +3
Query: 183 LDQFLSAAVDAAQKAGQVIRKGFYETKHVEHKGQVDLVTETDKGCEELVFNHLKHLFPNH 362
+++F+ A++AA+KAG++IR GFY++KH+EHKG VDLVTETDK CE L+FNHLK FP+H
Sbjct: 1 MEEFVDVAIEAAKKAGEIIRHGFYKSKHIEHKGVVDLVTETDKACEVLIFNHLKQCFPSH 60
Query: 363 KFIGEETT-AANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVVGVVYN 539
KFIGEETT AA+G ELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTI K PVVGVVYN
Sbjct: 61 KFIGEETTAAASGNFELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIEKKPVVGVVYN 120
Query: 540 PIMDELFTGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDDATNRINSLLT 719
PI+DELFT + G+GAFLNGK I+VS++S+LV AL+ E GT RDKA +D T RIN ++
Sbjct: 121 PIIDELFTAIYGRGAFLNGKSIRVSSESQLVKALVATEVGTNRDKAIVDATTGRINRVIF 180
Query: 720 KVRSLRMGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPSGKELD 899
KVRSLRM GSCAL+LCGVACGR D+FYEI FGGPWD+AAG +IV EAGGL+ DPSG E D
Sbjct: 181 KVRSLRMSGSCALNLCGVACGRLDLFYEIEFGGPWDVAAGALIVIEAGGLVLDPSGSEFD 240
Query: 900 ITSQRIAASNASLKELFVEAL 962
+T++R+AA+NA LK+ F+ AL
Sbjct: 241 LTARRVAATNAHLKDAFINAL 261
>sp|Q54U72|IMPA1_DICDI Inositol monophosphatase OS=Dictyostelium discoideum
GN=impa1 PE=3 SV=1
Length = 272
Score = 221 bits (562), Expect = 9e-057
Identities = 115/258 (44%), Positives = 166/258 (64%), Gaps = 4/258 (1%)
Frame = +3
Query: 171 ENGSLDQFLSAAVDAAQKAGQVIRKGF-YETKHVEHKGQVDLVTETDKGCEELVFNHLKH 347
EN +LDQ+L +AVD ++ G +I K + +K +E+KG +DLVT+TDK EE + L
Sbjct: 2 ENITLDQYLQSAVDVVKEIGPMILKNYNSRSKQIEYKGAIDLVTDTDKAVEEHIIKTLTT 61
Query: 348 LFPNHKFIGEETTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVVG 527
+P+ K +GEE+T +G+ +EPTW++DP+DGTTNFVH FP CVSI L+I K VV
Sbjct: 62 KYPHTKILGEEST-KDGIYNWGNEPTWVIDPIDGTTNFVHRFPLFCVSIALSINKEIVVA 120
Query: 528 VVYNPIMDELFTGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKR-DKATLDDATNRI 704
+Y P++DELFT +G GAFLNG+ I VS+ L +++ G R DK TN
Sbjct: 121 CLYAPVLDELFTATKGGGAFLNGESISVSSVEHLSQSIISTNVGYDRSDKGIEFMLTNFK 180
Query: 705 NSLLTKVRSLRMGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPS 884
N L V++LR G+ A ++ V+CGR D FYE G PWDIAA +++ EAGG++ DPS
Sbjct: 181 NILKDNVQALRFSGTAAWEMASVSCGRVDSFYEWGI-HPWDIAAASLLITEAGGVVVDPS 239
Query: 885 GKELDITSQRIAASNASL 938
G + D+ S+++ N ++
Sbjct: 240 GGKCDMESRKVLCGNPNI 257
>sp|Q8CIN7|IMPA2_RAT Inositol monophosphatase 2 OS=Rattus norvegicus GN=Impa2
PE=2 SV=1
Length = 290
Score = 215 bits (546), Expect = 6e-055
Identities = 119/269 (44%), Positives = 163/269 (60%), Gaps = 4/269 (1%)
Frame = +3
Query: 177 GSLDQFLSAAVDAAQKAGQVIRKGFYETKHVEHK-GQVDLVTETDKGCEELVFNHLKHLF 353
G D+ AV A +AGQ+IRK E KHV K DLVTETD E+L+ + L+ F
Sbjct: 16 GPWDECFEVAVQLALRAGQIIRKALTEEKHVSTKTSAADLVTETDHRVEDLIVSELRKRF 75
Query: 354 PNHKFIGEETTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVVGVV 533
P+H+FI EE TA+ LT PTWI+DP+DGT NFVH FP V VSIG + + GV+
Sbjct: 76 PSHRFIAEEATASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVI 135
Query: 534 YNPIMDELFTGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDDATNRINSL 713
++ + L+TG +G+GAF NG+ ++VS +++L AL+L E G KRD TL + + L
Sbjct: 136 HHCTEERLYTGRRGQGAFCNGQRLQVSRETDLAKALVLTEIGPKRDPDTLKVFLSNMERL 195
Query: 714 L-TKVRSLRMGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPSGK 890
L K +R+ GS L LC +A G D +Y+ G WD+AA VI+REAGG++ D SG
Sbjct: 196 LHAKAHGVRVIGSSTLALCYLASGAADAYYQFGL-HCWDLAAATVIIREAGGIVIDTSGG 254
Query: 891 ELDITSQR-IAASNASLKELFVEALRLTN 974
LD+ S R +AA + L +AL+ N
Sbjct: 255 PLDLMSCRVVAAGTREMAVLIAQALQTIN 283
>sp|O14732|IMPA2_HUMAN Inositol monophosphatase 2 OS=Homo sapiens GN=IMPA2 PE=1
SV=1
Length = 288
Score = 214 bits (544), Expect = 1e-054
Identities = 119/269 (44%), Positives = 164/269 (60%), Gaps = 4/269 (1%)
Frame = +3
Query: 177 GSLDQFLSAAVDAAQKAGQVIRKGFYETKHVEHK-GQVDLVTETDKGCEELVFNHLKHLF 353
G ++ AAV A +AGQ+IRK E K V K DLVTETD E+L+ + L+ F
Sbjct: 14 GPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRERF 73
Query: 354 PNHKFIGEETTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVVGVV 533
P+H+FI EE A+ LT PTWI+DP+DGT NFVH FP V VSIG + + GV+
Sbjct: 74 PSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGVI 133
Query: 534 YNPIMDELFTGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDDATNRINSL 713
Y+ + L+TG +G+GAF NG+ ++VS +++L AL+L E G KRD ATL + + L
Sbjct: 134 YHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMERL 193
Query: 714 L-TKVRSLRMGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPSGK 890
L K +R+ GS L LC +A G D +Y+ G WD+AA VI+REAGG++ D SG
Sbjct: 194 LHAKAHGVRVIGSSTLALCHLASGAADAYYQFGL-HCWDLAAATVIIREAGGIVIDTSGG 252
Query: 891 ELDITSQR-IAASNASLKELFVEALRLTN 974
LD+ + R +AAS + L +AL+ N
Sbjct: 253 PLDLMACRVVAASTREMAMLIAQALQTIN 281
>sp|Q91UZ5|IMPA2_MOUSE Inositol monophosphatase 2 OS=Mus musculus GN=Impa2 PE=1
SV=1
Length = 290
Score = 212 bits (538), Expect = 5e-054
Identities = 118/269 (43%), Positives = 162/269 (60%), Gaps = 4/269 (1%)
Frame = +3
Query: 177 GSLDQFLSAAVDAAQKAGQVIRKGFYETKHVEHK-GQVDLVTETDKGCEELVFNHLKHLF 353
G D+ AV A +AGQ+IRK E K V K DLVTETD E+L+ + L+ F
Sbjct: 16 GPWDECFEVAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHRVEDLIVSELRKRF 75
Query: 354 PNHKFIGEETTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVVGVV 533
P+H+FI EE TA+ LT PTWI+DP+DGT NFVH FP V VSIG + + GV+
Sbjct: 76 PSHRFIAEEATASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVHQELEFGVI 135
Query: 534 YNPIMDELFTGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDDATNRINSL 713
++ + L+TG +G+GAF NG+ ++VS +++L AL+L E G KRD TL + + L
Sbjct: 136 HHCTEERLYTGRRGQGAFCNGQRLQVSRETDLAKALVLTEIGPKRDPDTLKVFLSNMERL 195
Query: 714 L-TKVRSLRMGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPSGK 890
L K +R+ GS L LC +A G D +Y+ G WD+AA VI+REAGG++ D SG
Sbjct: 196 LHAKAHGVRVIGSSTLALCYLASGAADAYYQFGL-HCWDLAAATVIIREAGGIVIDTSGG 254
Query: 891 ELDITSQR-IAASNASLKELFVEALRLTN 974
LD+ S R +AA + L +AL+ N
Sbjct: 255 PLDLMSCRVVAAGTREMAVLIAQALQTIN 283
>sp|P20456|IMPA1_BOVIN Inositol monophosphatase 1 OS=Bos taurus GN=IMPA1 PE=1
SV=1
Length = 277
Score = 207 bits (525), Expect = 2e-052
Identities = 109/258 (42%), Positives = 164/258 (63%), Gaps = 4/258 (1%)
Frame = +3
Query: 204 AVDAAQKAGQVIRKGFYETKHVEHKGQ-VDLVTETDKGCEELVFNHLKHLFPNHKFIGEE 380
AV A +AG+V+R+ ++ K DLVT TD+ E+++ +K +P+H FIGEE
Sbjct: 12 AVTLAGQAGEVVREALKNEMNIMVKSSPADLVTATDQKVEKMLITSIKEKYPSHSFIGEE 71
Query: 381 TTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVVGVVYNPIMDELF 560
+ AA + LTD PTWI+DP+DGTTNFVHGFPFV VSIG + K G+VY+ + D+++
Sbjct: 72 SVAAGEKSILTDNPTWIIDPIDGTTNFVHGFPFVAVSIGFVVNKKMEFGIVYSCLEDKMY 131
Query: 561 TGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDDATNRINSLL-TKVRSLR 737
TG +GKGAF NG+ ++VS Q ++ +LL+ E G+ R T+ + I LL + +R
Sbjct: 132 TGRKGKGAFCNGQKLQVSHQEDITKSLLVTELGSSRTPETVRIILSNIERLLCLPIHGIR 191
Query: 738 MGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPSGKELDITSQR- 914
G+ AL++C VA G D +YE+G WD+A +IV EAGG++ D +G D+ S+R
Sbjct: 192 GVGTAALNMCLVAAGAADAYYEMGI-HCWDVAGAGIIVTEAGGVLLDVTGGPFDLMSRRV 250
Query: 915 IAASNASLKELFVEALRL 968
IA+SN +L E + +++
Sbjct: 251 IASSNKTLAERIAKEIQI 268
>sp|O77591|IMPA1_PIG Inositol monophosphatase 1 OS=Sus scrofa GN=IMPA1 PE=2
SV=1
Length = 277
Score = 203 bits (516), Expect = 2e-051
Identities = 107/258 (41%), Positives = 166/258 (64%), Gaps = 4/258 (1%)
Frame = +3
Query: 204 AVDAAQKAGQVIRKGFYETKHVEHKGQ-VDLVTETDKGCEELVFNHLKHLFPNHKFIGEE 380
AV A++AG+++R+ ++ K DLVT TD+ E+++ + +K +P+H FIGEE
Sbjct: 12 AVTLARQAGEIVREALKNEMNIMIKSSPADLVTATDEKVEKMLISSIKEKYPSHSFIGEE 71
Query: 381 TTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVVGVVYNPIMDELF 560
+ AA + LTD PTWI+DP+DGTTNFVHGFPFV VSIG + K GVVY+ + D+++
Sbjct: 72 SVAAGEKSVLTDNPTWIIDPIDGTTNFVHGFPFVAVSIGFVVNKGMEFGVVYSCMEDKMY 131
Query: 561 TGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDDATNRINSLL-TKVRSLR 737
TG +G+GAF +G+ ++VS Q ++ +LL+ E G+ R T+ + + LL + +R
Sbjct: 132 TGRKGRGAFCDGQKLQVSPQKDVTNSLLVTELGSSRTPETVRIILSNMERLLCIPIHGIR 191
Query: 738 MGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPSGKELDITSQR- 914
G+ AL++C VA G D FYE+G WD+A +IV EAGG++ D +G D+ S+R
Sbjct: 192 GVGTAALNMCFVAAGVADAFYEMGI-HCWDMAGAGIIVTEAGGVLMDITGGPFDLMSRRV 250
Query: 915 IAASNASLKELFVEALRL 968
IA+SN +L E + +++
Sbjct: 251 IASSNKALGERIAKEIQI 268
>sp|P97697|IMPA1_RAT Inositol monophosphatase 1 OS=Rattus norvegicus GN=Impa1
PE=1 SV=2
Length = 277
Score = 200 bits (507), Expect = 2e-050
Identities = 108/258 (41%), Positives = 162/258 (62%), Gaps = 4/258 (1%)
Frame = +3
Query: 204 AVDAAQKAGQVIRKGFYETKHVEHKGQ-VDLVTETDKGCEELVFNHLKHLFPNHKFIGEE 380
AV A++AG++IR+ V K DLVT TD+ E+++ + +K +P H FIGEE
Sbjct: 12 AVILARQAGEMIREALKNKMDVMIKSSPADLVTVTDQKVEKMLMSSIKEKYPYHSFIGEE 71
Query: 381 TTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVVGVVYNPIMDELF 560
+ A+ T T++PTWI+DP+DGTTNFVH FPFV VSIG + K GVVY+ + D+++
Sbjct: 72 SVASGEKTVFTEQPTWIIDPIDGTTNFVHRFPFVAVSIGFVVNKEMEFGVVYSCVEDKMY 131
Query: 561 TGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDDATNRINSLLT-KVRSLR 737
TG +GKGAF NG+ ++VS Q ++ +LL+ E G+ R TL + + L + + +R
Sbjct: 132 TGRKGKGAFCNGQKLRVSQQEDITKSLLVTELGSSRKPETLRIVLSNMERLCSIPIHGIR 191
Query: 738 MGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPSGKELDITSQR- 914
G+ A+++C VA G D +YE+G WD+A +IV EAGG++ D +G D+ S+R
Sbjct: 192 SVGTAAVNMCLVATGGADAYYEMGI-HCWDMAGAGIIVIEAGGVLLDVTGGPFDLMSRRI 250
Query: 915 IAASNASLKELFVEALRL 968
IAASN +L E + L +
Sbjct: 251 IAASNIALAERIAKELEI 268
>sp|P29219|IMPA1_XENLA Inositol monophosphatase 1 OS=Xenopus laevis GN=impa1
PE=2 SV=1
Length = 285
Score = 197 bits (499), Expect = 2e-049
Identities = 107/261 (40%), Positives = 159/261 (60%), Gaps = 7/261 (2%)
Frame = +3
Query: 204 AVDAAQKAGQVIRKGFYETKHVEHK---GQVDLVTETDKGCEELVFNHLKHLFPNHKFIG 374
AV A+KAG V+ E + K DLVT TD+ EE++ + +K +P+H FIG
Sbjct: 13 AVSIARKAGSVVCAALKEDVSIMVKTSLAPADLVTATDQKVEEMIISSIKEKYPSHSFIG 72
Query: 375 EETTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVVGVVYNPIMDE 554
EE+ AA + LTD PTWI+DP+DGTTNFVH FPFV VSIG + K GVVY+ + D+
Sbjct: 73 EESVAAGAGSTLTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVHKQVEFGVVYSCVEDK 132
Query: 555 LFTGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLD--DATNRINSLLTKVR 728
++TG +GKG+F NG+ ++VS Q ++ ++++ E G+ R+ + +N L +
Sbjct: 133 MYTGRKGKGSFCNGQKLQVSGQKDITKSMIITELGSNRNPEFIKTVSLSNMERLLCIPIH 192
Query: 729 SLRMGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPSGKELDITS 908
+R G+ A+++C VA G D +YE+G WD+AA VIV EAGG I D +G D+ S
Sbjct: 193 GIRAVGTAAVNMCLVATGGADAYYEMGL-HCWDMAAASVIVTEAGGTILDATGGLFDLMS 251
Query: 909 QR-IAASNASLKELFVEALRL 968
R I+AS+ + E + L++
Sbjct: 252 CRIISASSREIAERIAKELQI 272
>sp|P29218|IMPA1_HUMAN Inositol monophosphatase 1 OS=Homo sapiens GN=IMPA1 PE=1
SV=1
Length = 277
Score = 196 bits (496), Expect = 4e-049
Identities = 106/258 (41%), Positives = 161/258 (62%), Gaps = 4/258 (1%)
Frame = +3
Query: 204 AVDAAQKAGQVIRKGFYETKHVEHKGQ-VDLVTETDKGCEELVFNHLKHLFPNHKFIGEE 380
AV A++AG+V+ + +V K VDLVT TD+ E+++ + +K +P+H FIGEE
Sbjct: 12 AVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEE 71
Query: 381 TTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVVGVVYNPIMDELF 560
+ AA + LTD PTWI+DP+DGTTNFVH FPFV VSIG + K GVVY+ + +++
Sbjct: 72 SVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMY 131
Query: 561 TGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDDATNRINSLL-TKVRSLR 737
T +GKGAF NG+ ++VS Q ++ +LL+ E G+ R T+ + + L V +R
Sbjct: 132 TARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIR 191
Query: 738 MGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPSGKELDITSQR- 914
G+ A+++C VA G D +YE+G WD+A +IV EAGG++ D +G D+ S+R
Sbjct: 192 SVGTAAVNMCLVATGGADAYYEMGI-HCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRV 250
Query: 915 IAASNASLKELFVEALRL 968
IAA+N L E + +++
Sbjct: 251 IAANNRILAERIAKEIQV 268
>sp|O55023|IMPA1_MOUSE Inositol monophosphatase 1 OS=Mus musculus GN=Impa1 PE=1
SV=1
Length = 277
Score = 196 bits (496), Expect = 4e-049
Identities = 102/245 (41%), Positives = 154/245 (62%), Gaps = 3/245 (1%)
Frame = +3
Query: 204 AVDAAQKAGQVIRKGFYETKHVEHKGQ-VDLVTETDKGCEELVFNHLKHLFPNHKFIGEE 380
AV A++AG++IR+ V K DLVT TD+ E+++ + +K +P H FIGEE
Sbjct: 12 AVILARQAGEMIREALKNEMDVMIKSSPADLVTVTDQKVEKMLMSSIKEKYPCHSFIGEE 71
Query: 381 TTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVVGVVYNPIMDELF 560
+ AA T T+ PTW +DP+DGTTNFVH FPFV VSIG + K G+VY+ + D+++
Sbjct: 72 SVAAGEKTVFTESPTWFIDPIDGTTNFVHRFPFVAVSIGFLVNKEMEFGIVYSCVEDKMY 131
Query: 561 TGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDDATNRINSLLT-KVRSLR 737
TG +GKGAF NG+ ++VS Q ++ +LL+ E G+ R TL + + L + + +R
Sbjct: 132 TGRKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRKPETLRIVLSNMEKLCSIPIHGIR 191
Query: 738 MGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPSGKELDITSQRI 917
G+ A+++C VA G D +YE+G WD+A +IV EAGG++ D +G D+ S+RI
Sbjct: 192 SVGTAAVNMCLVATGGADAYYEMGI-HCWDMAGAGIIVTEAGGVLMDVTGGPFDLMSRRI 250
Query: 918 AASNA 932
A+N+
Sbjct: 251 IAANS 255
>sp|Q5R4X0|IMPA1_PONAB Inositol monophosphatase 1 OS=Pongo abelii GN=IMPA1 PE=2
SV=1
Length = 277
Score = 196 bits (496), Expect = 4e-049
Identities = 106/258 (41%), Positives = 161/258 (62%), Gaps = 4/258 (1%)
Frame = +3
Query: 204 AVDAAQKAGQVIRKGFYETKHVEHKGQ-VDLVTETDKGCEELVFNHLKHLFPNHKFIGEE 380
AV A++AG+V+ + +V K VDLVT TD+ E+++ + +K +P+H FIGEE
Sbjct: 12 AVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEE 71
Query: 381 TTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVVGVVYNPIMDELF 560
+ AA + LTD PTWI+DP+DGTTNFVH FPFV VSIG + K GVVY+ + +++
Sbjct: 72 SVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMY 131
Query: 561 TGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDDATNRINSLL-TKVRSLR 737
T +GKGAF NG+ ++VS Q ++ +LL+ E G+ R T+ + + L V +R
Sbjct: 132 TARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRIVLSNMEKLFCIPVHGIR 191
Query: 738 MGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPSGKELDITSQR- 914
G+ A+++C VA G D +YE+G WD+A +IV EAGG++ D +G D+ S+R
Sbjct: 192 SVGTAAVNMCLVATGGADAYYEMGI-HCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRV 250
Query: 915 IAASNASLKELFVEALRL 968
IAA+N L E + +++
Sbjct: 251 IAANNRILAERIAKEIQV 268
>sp|P74158|SUHB_SYNY3 Inositol-1-monophosphatase OS=Synechocystis sp. (strain
PCC 6803) GN=suhB PE=3 SV=1
Length = 287
Score = 182 bits (461), Expect = 4e-045
Identities = 110/265 (41%), Positives = 149/265 (56%), Gaps = 8/265 (3%)
Frame = +3
Query: 183 LDQFLSAAVDAAQKAGQVIRKGFYETKHVEHKGQV-DLVTETDKGCEELVFNHLKHLFPN 359
L +L A +A AG I + + + ++ KG+ DLVTE D+ E ++ +K P+
Sbjct: 14 LQTWLEIATEAVLAAGAEIFSLWGKVQQIQEKGRAGDLVTEADRQAEAIILEIIKRRCPD 73
Query: 360 HKFIGEETTAANGVTELTDEP-TWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVVGVVY 536
H + EE +G D P W +DPLDGTTNF H +P CVSIGL I +P VGVVY
Sbjct: 74 HAILAEE----SGQLGQVDNPFCWAIDPLDGTTNFAHSYPVSCVSIGLLIQDIPTVGVVY 129
Query: 537 NPIMDELFTGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDDATNRINSLL 716
NP ELF GA LN +PI+VST + L +LL+ R K TLD+ L
Sbjct: 130 NPFRQELFRAATSLGATLNRRPIQVSTTASLDKSLLVTGFAYDRVK-TLDNNYPEFCYLT 188
Query: 717 TKVRSLRMGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPSGKEL 896
+ +R GS A+DL VACGR D ++E G PWD+AAGIVIVREAGG++ L
Sbjct: 189 HLTQGVRRSGSAAIDLIDVACGRLDGYWERGI-NPWDMAAGIVIVREAGGIVSAYDCSPL 247
Query: 897 DITSQRIAASNASLKELFVEALRLT 971
D+++ RI A+N + + +AL T
Sbjct: 248 DLSTGRILATNGKIHQELSQALAAT 272
>sp|Q19420|IMPA1_CAEEL Inositol monophosphatase ttx-7 OS=Caenorhabditis elegans
GN=ttx-7 PE=1 SV=2
Length = 285
Score = 179 bits (452), Expect = 5e-044
Identities = 99/256 (38%), Positives = 148/256 (57%), Gaps = 10/256 (3%)
Frame = +3
Query: 192 FLSAAVDAAQKAGQVIRKGF--YETKHVEHKGQVDLVTETDKGCEELVFNHLKHLFPNHK 365
F+ A++ +KAG ++R F E+K DLVTETD+ E+L+ L F H+
Sbjct: 13 FVDYAIELVKKAGTLVRTAFDSPESKVDTKSSNTDLVTETDQAVEKLLIEGLSERFKGHR 72
Query: 366 FIGEETTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVVGVVYNPI 545
FIGEE+ A E TD PTWI+DP+DGTTNFVH P + + +GL I K G+VYNPI
Sbjct: 73 FIGEESVAGGAKIEWTDAPTWIIDPIDGTTNFVHRIPMIAICVGLAIKKQIRAGIVYNPI 132
Query: 546 MDELFTGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDD------ATNRIN 707
+EL+ GKGAF NG PI+ S +++L++ +L ++ ++ D +N N
Sbjct: 133 TNELYLAQLGKGAFKNGFPIRAS-KNQLLSKGVLCQSLGLHNRVQFGDRWLDIAQSNMRN 191
Query: 708 SLLTKVRSLRMGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPSG 887
++ VR R GS A+++ VA G D + E G WD+AA +IV EAGG++ DP+G
Sbjct: 192 QVMAGVRGHRSFGSGAINMVMVAQGSCDGYVEYGIHA-WDVAAPSIIVTEAGGVVTDPTG 250
Query: 888 KELDITSQRIAASNAS 935
D+ S+++ + +
Sbjct: 251 SPFDVMSRKVLCAGTA 266
>sp|Q9CNV8|SUHB_PASMU Inositol-1-monophosphatase OS=Pasteurella multocida
GN=suhB PE=3 SV=1
Length = 267
Score = 163 bits (410), Expect = 4e-039
Identities = 101/254 (39%), Positives = 145/254 (57%), Gaps = 8/254 (3%)
Frame = +3
Query: 195 LSAAVDAAQKAGQVIRKGFYETKHVEH--KGQVDLVTETDKGCEELVFNHLKHLFPNHKF 368
L+ A+ AA+KAG VI KG+ ++ K D VT DK EE + ++ +P+H
Sbjct: 5 LNIAIRAARKAGNVIAKGYERRDDLQTTLKSTNDYVTNIDKASEEAIIEVIRKSYPDHTI 64
Query: 369 IGEETTAANGVTELTDEPTWIVDPLDGTTNFVHGFPFVCVSIGLTIGKVPVVGVVYNPIM 548
I EE+ A G + W++DPLDGTTNFV G P VSI + + VGVVY+PI
Sbjct: 65 ITEESGALEG---KDSDIQWVIDPLDGTTNFVKGLPHFSVSIAIRVKGRTEVGVVYDPIR 121
Query: 549 DELFTGVQGKGAFLNGKPIKVSTQSELVTALLLAEAGTKRDKATLDDATNRINSLLTKVR 728
+ELFT V+G+GA +N ++V + +L +L K+ + + +N+L+
Sbjct: 122 NELFTAVRGEGAKINDMRLRVENKRDLAGTVLTTGFPFKQTR-LMPMQFAMMNNLIQDCA 180
Query: 729 SLRMGGSCALDLCGVACGRGDIFYEIGFGGPWDIAAGIVIVREAGGLIFDPSGKELDITS 908
R GS ALDLC VA GR D ++E+G WDIAAG +IVREAGGL+ D +G +TS
Sbjct: 181 DFRRMGSAALDLCYVAAGRVDGYFEVGVKA-WDIAAGDLIVREAGGLVCDFNGGHSYLTS 239
Query: 909 -QRIAASNASLKEL 947
+AA+ +KE+
Sbjct: 240 GHLVAAAPRIVKEI 253
>sp|Q05533|INM2_YEAST Inositol monophosphatase 2 OS=Saccharomyces cerevisiae
GN=INM2 PE=1 SV=1
Length = 292
Score = 161 bits (405), Expect = 1e-038
Identities = 93/218 (42%), Positives = 134/218 (61%), Gaps = 10/218 (4%)
Frame = +3
Query: 285 VDLVTETDKGCEELVFNHLKHLFPNHKFIGEETTAANGVTELTDEPTWIVDPLDGTTNFV 464
VDLVT DK E ++ +L +P+ KFIGEE T GVT++T+ PT+IVDP+DGTTNF+
Sbjct: 45 VDLVTALDKQIESIIKENLTAKYPSFKFIGEE-TYVKGVTKITNGPTFIVDPIDGTTNFI 103
Query: 465 HGFPFVCVSIGLTIGKVPVVGVVYNPIMDELFTGVQGKGAFLNGKPIKVSTQSELVTALL 644
HG+P+ C S+GL PVVGVV+NP +++LF +G GAFLN + IKVS + ++ L
Sbjct: 104 HGYPYSCTSLGLAEMGKPVVGVVFNPHLNQLFHASKGNGAFLNDQEIKVSKRPLILQKSL 163
Query: 645 LA-EAGTKR---DKATLDDATNRINSLLTK----VRSLRMGGSCALDLCGVACGRGDIFY 800
+A E G++R + D N +LL++ V R GS A+++C VA G D ++
Sbjct: 164 IALEGGSERTEGSQGNFDKKMNTYKNLLSESGAFVHGFRSAGSAAMNICYVASGMLDAYW 223
Query: 801 EIGFGGPWDIAAGIVIVREAGGLIFDPSGKELDITSQR 914
E G WD+ AG I+ EAGG++ + E +I R
Sbjct: 224 EGGCWA-WDVCAGWCILEEAGGIMVGGNCGEWNIPLDR 260
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,767,994,010
Number of Sequences: 518415
Number of Extensions: 98767994010
Number of Successful Extensions: 632508636
Number of sequences better than 0.0: 0
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