BLASTX 7.6.2
Query= UN23605 /QuerySize=1598
(1597 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O75494|SF13A_HUMAN Splicing factor, arginine/serine-rich 13A ... 87 2e-016
sp|Q9R0U0|SF13A_MOUSE Splicing factor, arginine/serine-rich 13A ... 87 2e-016
sp|Q8WXF0|SF13B_HUMAN Splicing factor, arginine/serine-rich 13B ... 75 1e-012
sp|Q9UQ35|SRRM2_HUMAN Serine/arginine repetitive matrix protein ... 61 2e-008
sp|Q18409|RSP6_CAEEL Probable splicing factor, arginine/serine-r... 56 6e-007
sp|Q06A98|SFRS2_PIG Splicing factor, arginine/serine-rich 2 OS=S... 56 6e-007
sp|P30352|SFRS2_CHICK Splicing factor, arginine/serine-rich 2 OS... 56 8e-007
sp|Q3MHR5|SFRS2_BOVIN Splicing factor, arginine/serine-rich 2 OS... 55 1e-006
sp|Q01130|SFRS2_HUMAN Splicing factor, arginine/serine-rich 2 OS... 55 1e-006
sp|Q62093|SFRS2_MOUSE Splicing factor, arginine/serine-rich 2 OS... 55 1e-006
sp|Q6PDU1|SFRS2_RAT Splicing factor, arginine/serine-rich 2 OS=R... 55 1e-006
sp|A7MD48|SRRM4_HUMAN Serine/arginine repetitive matrix protein ... 55 1e-006
sp|Q5R1W5|SFRS2_PANTR Splicing factor, arginine/serine-rich 2 OS... 55 1e-006
sp|A6QLS2|RSRC2_BOVIN Arginine/serine-rich coiled-coil protein 2... 54 3e-006
sp|Q7L4I2|RSRC2_HUMAN Arginine/serine-rich coiled-coil protein 2... 53 5e-006
sp|Q5R8J6|RSRC2_PONAB Arginine/serine-rich coiled-coil protein 2... 53 5e-006
sp|Q7RYH7|CWC21_NEUCR Pre-mRNA-splicing factor cwc-21 OS=Neurosp... 53 6e-006
sp|A2RTL5|RSRC2_MOUSE Arginine/serine-rich coiled-coil protein 2... 52 8e-006
sp|Q5PQR4|RSRC2_RAT Arginine/serine-rich coiled-coil protein 2 O... 52 8e-006
>sp|O75494|SF13A_HUMAN Splicing factor, arginine/serine-rich 13A OS=Homo sapiens
GN=SFRS13A PE=1 SV=1
Length = 262
Score = 87 bits (215), Expect = 2e-016
Identities = 58/140 (41%), Positives = 78/140 (55%), Gaps = 11/140 (7%)
Frame = -3
Query: 656 REPRGFGFVQYYDPDDAADAKYHLDGYVLLGREITVVFAEENRKKPSEMRER------SR 495
R PRGF +VQ+ D DA DA ++LD + GR+I + FA+ +RK P++M+ + S
Sbjct: 48 RRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSS 107
Query: 494 GRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYS---RSPYDGRHRSRSVSPGDRR 324
R Y SRS Y R + RS+ + YRRSYS P RSRS S DR
Sbjct: 108 SRYDDYDRYRRSRSRSYERRRSRSRSFDYN--YRRSYSPRNSRPTGRPRRSRSHSDNDRF 165
Query: 323 RSYSRSSSRSRYESRSRSQS 264
+ +RS SRS+ SRSRS+S
Sbjct: 166 KHRNRSFSRSKSNSRSRSKS 185
>sp|Q9R0U0|SF13A_MOUSE Splicing factor, arginine/serine-rich 13A OS=Mus musculus
GN=Sfrs13a PE=1 SV=2
Length = 262
Score = 87 bits (215), Expect = 2e-016
Identities = 58/140 (41%), Positives = 78/140 (55%), Gaps = 11/140 (7%)
Frame = -3
Query: 656 REPRGFGFVQYYDPDDAADAKYHLDGYVLLGREITVVFAEENRKKPSEMRER------SR 495
R PRGF +VQ+ D DA DA ++LD + GR+I + FA+ +RK P++M+ + S
Sbjct: 48 RRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSS 107
Query: 494 GRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYS---RSPYDGRHRSRSVSPGDRR 324
R Y SRS Y R + RS+ + YRRSYS P RSRS S DR
Sbjct: 108 SRYDDYDRYRRSRSRSYERRRSRSRSFDYN--YRRSYSPRNSRPTGRPRRSRSHSDNDRF 165
Query: 323 RSYSRSSSRSRYESRSRSQS 264
+ +RS SRS+ SRSRS+S
Sbjct: 166 KHRNRSFSRSKSNSRSRSKS 185
>sp|Q8WXF0|SF13B_HUMAN Splicing factor, arginine/serine-rich 13B OS=Homo sapiens
GN=SFRS13B PE=1 SV=1
Length = 261
Score = 75 bits (183), Expect = 1e-012
Identities = 56/142 (39%), Positives = 78/142 (54%), Gaps = 18/142 (12%)
Frame = -3
Query: 656 REPRGFGFVQYYDPDDAADAKYHLDGYVLLGREITVVFAEENRKKPSEMRERSRGRTSTR 477
R PRGF +VQ+ D DA DA Y+L+ + GR+I + FA+ +RK P +M+ + R
Sbjct: 48 RRPRGFAYVQFEDVRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKER---HPC 104
Query: 476 SPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYSRSP--YDGRHR------SRSVSPGDRRR 321
SP + R SRSP+ RR+ SRS + R+ RS + RHR S+S S RR
Sbjct: 105 SPSDHRR----SRSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRR 160
Query: 320 SYSRSSSRS---RYESRSRSQS 264
S S SR+ + SR RS+S
Sbjct: 161 STSARQSRTPRRNFGSRGRSRS 182
>sp|Q9UQ35|SRRM2_HUMAN Serine/arginine repetitive matrix protein 2 OS=Homo
sapiens GN=SRRM2 PE=1 SV=2
Length = 2752
Score = 61 bits (147), Expect = 2e-008
Identities = 44/102 (43%), Positives = 54/102 (52%), Gaps = 9/102 (8%)
Frame = -3
Query: 566 GREITVVFAEENRKKPSEMRERSRGRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRS 387
GR + A + + R RSR RT R R SR+P RRS +RSPV RRS
Sbjct: 582 GRSRSRTPARRRSRSRTPTRRRSRSRTPAR------RGRSRSRTPARRRSRTRSPVRRRS 635
Query: 386 YSRSPYDGRHRSRSVSPGDRRRSYSRSSSRSRYESRSRSQSP 261
SRSP RSRS +P R RS SR+ +R RSRS++P
Sbjct: 636 RSRSPARRSGRSRSRTPARRGRSRSRTPAR---RGRSRSRTP 674
>sp|Q18409|RSP6_CAEEL Probable splicing factor, arginine/serine-rich 6
OS=Caenorhabditis elegans GN=rsp-6 PE=1 SV=1
Length = 179
Score = 56 bits (134), Expect = 6e-007
Identities = 39/79 (49%), Positives = 45/79 (56%), Gaps = 5/79 (6%)
Frame = -3
Query: 497 RGRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYSRSPYDGRHRSRSVSPGDRRRS 318
RGR+ +R SR G RS + R SR RS RS R RSRS SP +R RS
Sbjct: 105 RGRSRSR-----SRDRGRDRSRDRSRDRSRDRSRDRSRERSRERERTRSRSRSPQERDRS 159
Query: 317 YSRSSSRSRYESRSRSQSP 261
+S+S SRSR SRSRS SP
Sbjct: 160 HSKSRSRSRSRSRSRSASP 178
>sp|Q06A98|SFRS2_PIG Splicing factor, arginine/serine-rich 2 OS=Sus scrofa
GN=SFRS2 PE=2 SV=1
Length = 221
Score = 56 bits (134), Expect = 6e-007
Identities = 43/93 (46%), Positives = 55/93 (59%), Gaps = 10/93 (10%)
Frame = -3
Query: 530 RKKPSEMRERSRGRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYSRSPYDGRHRS 351
R++ S R RSR R+ +RS YSRS SR+ + RS S+S RRS S+S R RS
Sbjct: 124 RRRRSRSRSRSRSRSRSRS--RYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRS 181
Query: 350 RSVSPGDRRRSYSRS---SSRSRYESRSRSQSP 261
RS R RS SRS +S+ +SRSRS+SP
Sbjct: 182 RS-----RSRSRSRSPPPASKRESKSRSRSKSP 209
>sp|P30352|SFRS2_CHICK Splicing factor, arginine/serine-rich 2 OS=Gallus gallus
GN=SFRS2 PE=2 SV=1
Length = 221
Score = 56 bits (133), Expect = 8e-007
Identities = 43/93 (46%), Positives = 54/93 (58%), Gaps = 10/93 (10%)
Frame = -3
Query: 530 RKKPSEMRERSRGRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYSRSPYDGRHRS 351
R++ S R RSR R+ +RS YSRS SR+ + RS S+S RRS S+S R RS
Sbjct: 124 RRRRSRSRSRSRSRSRSRS--RYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRS 181
Query: 350 RSVSPGDRRRSYSRS---SSRSRYESRSRSQSP 261
RS R RS SRS +S+ SRSRS+SP
Sbjct: 182 RS-----RSRSRSRSPPPTSKRESNSRSRSKSP 209
>sp|Q3MHR5|SFRS2_BOVIN Splicing factor, arginine/serine-rich 2 OS=Bos taurus
GN=SFRS2 PE=2 SV=3
Length = 221
Score = 55 bits (132), Expect = 1e-006
Identities = 43/93 (46%), Positives = 54/93 (58%), Gaps = 10/93 (10%)
Frame = -3
Query: 530 RKKPSEMRERSRGRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYSRSPYDGRHRS 351
R++ S R RSR R+ +RS YSRS SR+ + RS S+S RRS S+S R RS
Sbjct: 124 RRRRSRSRSRSRSRSRSRS--RYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRS 181
Query: 350 RSVSPGDRRRSYSRSS---SRSRYESRSRSQSP 261
RS R RS SRS S+ +SRSRS+SP
Sbjct: 182 RS-----RSRSRSRSPPPVSKRESKSRSRSKSP 209
>sp|Q01130|SFRS2_HUMAN Splicing factor, arginine/serine-rich 2 OS=Homo sapiens
GN=SFRS2 PE=1 SV=4
Length = 221
Score = 55 bits (132), Expect = 1e-006
Identities = 43/93 (46%), Positives = 54/93 (58%), Gaps = 10/93 (10%)
Frame = -3
Query: 530 RKKPSEMRERSRGRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYSRSPYDGRHRS 351
R++ S R RSR R+ +RS YSRS SR+ + RS S+S RRS S+S R RS
Sbjct: 124 RRRRSRSRSRSRSRSRSRS--RYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRS 181
Query: 350 RSVSPGDRRRSYSRSS---SRSRYESRSRSQSP 261
RS R RS SRS S+ +SRSRS+SP
Sbjct: 182 RS-----RSRSRSRSPPPVSKRESKSRSRSKSP 209
>sp|Q62093|SFRS2_MOUSE Splicing factor, arginine/serine-rich 2 OS=Mus musculus
GN=Sfrs2 PE=1 SV=4
Length = 221
Score = 55 bits (132), Expect = 1e-006
Identities = 43/93 (46%), Positives = 54/93 (58%), Gaps = 10/93 (10%)
Frame = -3
Query: 530 RKKPSEMRERSRGRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYSRSPYDGRHRS 351
R++ S R RSR R+ +RS YSRS SR+ + RS S+S RRS S+S R RS
Sbjct: 124 RRRRSRSRSRSRSRSRSRS--RYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRS 181
Query: 350 RSVSPGDRRRSYSRSS---SRSRYESRSRSQSP 261
RS R RS SRS S+ +SRSRS+SP
Sbjct: 182 RS-----RSRSRSRSPPPVSKRESKSRSRSKSP 209
>sp|Q6PDU1|SFRS2_RAT Splicing factor, arginine/serine-rich 2 OS=Rattus
norvegicus GN=Sfrs2 PE=1 SV=3
Length = 221
Score = 55 bits (132), Expect = 1e-006
Identities = 43/93 (46%), Positives = 54/93 (58%), Gaps = 10/93 (10%)
Frame = -3
Query: 530 RKKPSEMRERSRGRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYSRSPYDGRHRS 351
R++ S R RSR R+ +RS YSRS SR+ + RS S+S RRS S+S R RS
Sbjct: 124 RRRRSRSRSRSRSRSRSRS--RYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRS 181
Query: 350 RSVSPGDRRRSYSRSS---SRSRYESRSRSQSP 261
RS R RS SRS S+ +SRSRS+SP
Sbjct: 182 RS-----RSRSRSRSPPPVSKRESKSRSRSKSP 209
>sp|A7MD48|SRRM4_HUMAN Serine/arginine repetitive matrix protein 4 OS=Homo
sapiens GN=SRRM4 PE=1 SV=2
Length = 611
Score = 55 bits (132), Expect = 1e-006
Identities = 40/79 (50%), Positives = 46/79 (58%), Gaps = 3/79 (3%)
Frame = -3
Query: 500 SRGRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYSRSPYDGRHRSRSVSPGDRRR 321
S G S+ S + YS S S S +Y RS SRS RRS +R+ SRS SPG R R
Sbjct: 526 SSGSLSSTSSW-YSSSSSRSASRSYSRSRSRSRSRRRSRTRT--SSSSSSRSPSPGSRSR 582
Query: 320 SYSRSSSRSRYESRSRSQS 264
S SRS SRSR S+SRS S
Sbjct: 583 SRSRSRSRSRSRSQSRSYS 601
>sp|Q5R1W5|SFRS2_PANTR Splicing factor, arginine/serine-rich 2 OS=Pan
troglodytes GN=SFRS2 PE=2 SV=3
Length = 221
Score = 55 bits (131), Expect = 1e-006
Identities = 43/93 (46%), Positives = 54/93 (58%), Gaps = 10/93 (10%)
Frame = -3
Query: 530 RKKPSEMRERSRGRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYSRSPYDGRHRS 351
R++ S R RSR R+ +RS YSRS SR+ + RS S+S RRS S+S R RS
Sbjct: 124 RRRRSRSRSRSRSRSRSRS--RYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRS 181
Query: 350 RSVSPGDRRRSYSRSS---SRSRYESRSRSQSP 261
RS R RS SRS S+ +SRSRS+SP
Sbjct: 182 RS-----RSRSRSRSPPPVSKREPKSRSRSKSP 209
>sp|A6QLS2|RSRC2_BOVIN Arginine/serine-rich coiled-coil protein 2 OS=Bos taurus
GN=RSRC2 PE=2 SV=2
Length = 435
Score = 54 bits (128), Expect = 3e-006
Identities = 43/96 (44%), Positives = 55/96 (57%), Gaps = 3/96 (3%)
Frame = -3
Query: 536 ENRKKPSEMRERSRGRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYSRSPYDGRH 357
E+R K E R+ SRGR+ +RS R SRS ++S SRS ++S SRS +
Sbjct: 109 EDRHKRKE-RKSSRGRSHSRSRSRERRH--RSRSRERKKSRSRSRDRKKSRSRSRERKKS 165
Query: 356 RSRSVSPGDRRRSYSRSSSRSRYESRSRSQSPGYSR 249
RSRS R RS SRS SR R+ SRSRS++ SR
Sbjct: 166 RSRSRERKRRIRSRSRSRSRHRHRSRSRSRTRSRSR 201
>sp|Q7L4I2|RSRC2_HUMAN Arginine/serine-rich coiled-coil protein 2 OS=Homo
sapiens GN=RSRC2 PE=1 SV=1
Length = 434
Score = 53 bits (126), Expect = 5e-006
Identities = 42/96 (43%), Positives = 55/96 (57%), Gaps = 3/96 (3%)
Frame = -3
Query: 536 ENRKKPSEMRERSRGRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYSRSPYDGRH 357
E+R K E R+ SRGR+ +RS R SRS ++S SRS ++S SRS +
Sbjct: 109 EDRHKRKE-RKSSRGRSHSRSRSRERRH--RSRSRERKKSRSRSRERKKSRSRSRERKKS 165
Query: 356 RSRSVSPGDRRRSYSRSSSRSRYESRSRSQSPGYSR 249
RSRS R RS SRS SR R+ +RSRS++ SR
Sbjct: 166 RSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSR 201
>sp|Q5R8J6|RSRC2_PONAB Arginine/serine-rich coiled-coil protein 2 OS=Pongo
abelii GN=RSRC2 PE=2 SV=1
Length = 435
Score = 53 bits (126), Expect = 5e-006
Identities = 42/96 (43%), Positives = 55/96 (57%), Gaps = 3/96 (3%)
Frame = -3
Query: 536 ENRKKPSEMRERSRGRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYSRSPYDGRH 357
E+R K E R+ SRGR+ +RS R SRS ++S SRS ++S SRS +
Sbjct: 109 EDRHKRKE-RKSSRGRSHSRSRSRERRH--RSRSRERKKSRSRSRERKKSRSRSRERKKS 165
Query: 356 RSRSVSPGDRRRSYSRSSSRSRYESRSRSQSPGYSR 249
RSRS R RS SRS SR R+ +RSRS++ SR
Sbjct: 166 RSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSR 201
>sp|Q7RYH7|CWC21_NEUCR Pre-mRNA-splicing factor cwc-21 OS=Neurospora crassa
GN=cwc-21 PE=3 SV=1
Length = 344
Score = 53 bits (125), Expect = 6e-006
Identities = 40/95 (42%), Positives = 48/95 (50%), Gaps = 3/95 (3%)
Frame = -3
Query: 533 NRKKPSEMRERSRGRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYSRSPYDGRHR 354
+R+ S R R+ +RSP R +RSP SRSPV RS SRS R
Sbjct: 241 DREVDSYRGAAGRDRSRSRSPI---RERSRTRSPVRDTGRSRSPVSERSLSRSRSRSRSY 297
Query: 353 SRSVSPGDRRRSYSRSSSRSRYESRSRSQSPGYSR 249
SRS SP RR + S+ S SR SRS S+SP R
Sbjct: 298 SRSRSPPRRRAADSQDRSLSRSRSRSYSRSPDRDR 332
>sp|A2RTL5|RSRC2_MOUSE Arginine/serine-rich coiled-coil protein 2 OS=Mus
musculus GN=Rsrc2 PE=2 SV=1
Length = 376
Score = 52 bits (124), Expect = 8e-006
Identities = 42/96 (43%), Positives = 55/96 (57%), Gaps = 3/96 (3%)
Frame = -3
Query: 536 ENRKKPSEMRERSRGRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYSRSPYDGRH 357
E+R K E R+ SRGR+ +RS R SRS ++S SRS ++S SRS +
Sbjct: 50 EDRHKRKE-RKSSRGRSHSRSRSRERRH--RSRSRERKKSRSRSRDRKKSRSRSRDRKKS 106
Query: 356 RSRSVSPGDRRRSYSRSSSRSRYESRSRSQSPGYSR 249
RSRS R R+ SRS SR R+ +RSRS+S SR
Sbjct: 107 RSRSRDRKRRIRTRSRSRSRHRHRTRSRSRSRSRSR 142
>sp|Q5PQR4|RSRC2_RAT Arginine/serine-rich coiled-coil protein 2 OS=Rattus
norvegicus GN=Rsrc2 PE=2 SV=1
Length = 376
Score = 52 bits (124), Expect = 8e-006
Identities = 42/96 (43%), Positives = 55/96 (57%), Gaps = 3/96 (3%)
Frame = -3
Query: 536 ENRKKPSEMRERSRGRTSTRSPYGYSRSPGYSRSPNYRRSYSRSPVYRRSYSRSPYDGRH 357
E+R K E R+ SRGR+ +RS R SRS ++S SRS ++S SRS +
Sbjct: 50 EDRHKRKE-RKSSRGRSHSRSRSRERRH--RSRSRERKKSRSRSRDRKKSRSRSRDRKKS 106
Query: 356 RSRSVSPGDRRRSYSRSSSRSRYESRSRSQSPGYSR 249
RSRS R R+ SRS SR R+ +RSRS+S SR
Sbjct: 107 RSRSRDRKRRIRTRSRSRSRHRHRTRSRSRSRSRSR 142
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,767,994,010
Number of Sequences: 518415
Number of Extensions: 98767994010
Number of Successful Extensions: 632508636
Number of sequences better than 0.0: 0
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