BLASTX 7.6.2
Query= UN23656 /QuerySize=818
(817 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O65404|ERG11_ARATH Squalene monooxygenase 1,1 OS=Arabidopsis ... 368 4e-101
sp|O65402|ERG12_ARATH Squalene monooxygenase 1,2 OS=Arabidopsis ... 358 3e-098
sp|O65726|ERG12_BRANA Squalene monooxygenase 1,2 OS=Brassica nap... 334 4e-091
sp|O65727|ERG11_BRANA Squalene monooxygenase 1,1 OS=Brassica nap... 330 1e-089
sp|O65403|ERG13_ARATH Squalene monooxygenase 2 OS=Arabidopsis th... 268 3e-071
sp|O48651|ERG1_PANGI Squalene monooxygenase OS=Panax ginseng PE=... 196 2e-049
sp|Q14534|ERG1_HUMAN Squalene monooxygenase OS=Homo sapiens GN=S... 97 2e-019
sp|Q9C1W3|ERG1_SCHPO Probable squalene monooxygenase OS=Schizosa... 96 3e-019
sp|P52019|ERG1_MOUSE Squalene monooxygenase OS=Mus musculus GN=S... 95 6e-019
sp|P52020|ERG1_RAT Squalene monooxygenase OS=Rattus norvegicus G... 95 6e-019
sp|Q92206|ERG1_CANAL Squalene monooxygenase OS=Candida albicans ... 84 1e-015
sp|P32476|ERG1_YEAST Squalene monooxygenase OS=Saccharomyces cer... 82 4e-015
sp|O13306|ERG1_CANGA Squalene monooxygenase OS=Candida glabrata ... 78 7e-014
sp|Q75F69|ERG1_ASHGO Squalene monooxygenase OS=Ashbya gossypii G... 73 2e-012
>sp|O65404|ERG11_ARATH Squalene monooxygenase 1,1 OS=Arabidopsis thaliana
GN=SQP1,1 PE=2 SV=2
Length = 516
Score = 368 bits (943), Expect = 4e-101
Identities = 185/210 (88%), Positives = 197/210 (93%)
Frame = -1
Query: 817 DEGAQIKTMPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLR 638
DEG IK MPTK+M ATLSEK+GVI+LGDAFNMRHPAIASGMMVLLSDILILRRLLQPL
Sbjct: 307 DEGEHIKAMPTKKMTATLSEKKGVILLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLS 366
Query: 637 NLGDANKISEVIKSFYIIRKPMSATVNTLGNAFSQVLVASTDEAKEAMQQGCFDYLSSGG 458
NLG+A KIS+VIKSFY IRKPMSATVNTLGNAFSQVLVASTDEAKEAM+QGC+DYLSSGG
Sbjct: 367 NLGNAQKISQVIKSFYDIRKPMSATVNTLGNAFSQVLVASTDEAKEAMRQGCYDYLSSGG 426
Query: 457 FRTSGMMALLGGMNPRPLSLIFHLCGITLSSIGQLLSPFPSPLRIWHSLRLFGLSMKMLI 278
FRTSGMMALLGGMNPRP+SLI+HLC ITLSSIG LLSPFPSPLRIWHSLRLFGL+MKML+
Sbjct: 427 FRTSGMMALLGGMNPRPISLIYHLCAITLSSIGHLLSPFPSPLRIWHSLRLFGLAMKMLV 486
Query: 277 PHLKAEGVSQMFYPAYAAAYRKSYMAATAL 188
PHLKAEGVSQM +P AAAY KSYMAATAL
Sbjct: 487 PHLKAEGVSQMLFPVNAAAYSKSYMAATAL 516
>sp|O65402|ERG12_ARATH Squalene monooxygenase 1,2 OS=Arabidopsis thaliana
GN=SQP1,2 PE=2 SV=1
Length = 517
Score = 358 bits (918), Expect = 3e-098
Identities = 178/210 (84%), Positives = 194/210 (92%)
Frame = -1
Query: 817 DEGAQIKTMPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLR 638
DEGA IK +P KRM +TLS+K+GVIVLGDAFNMRHP +ASGMMVLLSDILILRRLLQPL
Sbjct: 308 DEGAHIKVVPAKRMTSTLSKKKGVIVLGDAFNMRHPVVASGMMVLLSDILILRRLLQPLS 367
Query: 637 NLGDANKISEVIKSFYIIRKPMSATVNTLGNAFSQVLVASTDEAKEAMQQGCFDYLSSGG 458
NLGDANK+SEVI SFY IRKPMSATVNTLGNAFSQVL+ STDEAKEAM+QG +DYL SGG
Sbjct: 368 NLGDANKVSEVINSFYDIRKPMSATVNTLGNAFSQVLIGSTDEAKEAMRQGVYDYLCSGG 427
Query: 457 FRTSGMMALLGGMNPRPLSLIFHLCGITLSSIGQLLSPFPSPLRIWHSLRLFGLSMKMLI 278
FRTSGMMALLGGMNPRPLSL++HLC ITLSSIGQLLSPFPSPLRIWHSL+LFGL+MKML+
Sbjct: 428 FRTSGMMALLGGMNPRPLSLVYHLCAITLSSIGQLLSPFPSPLRIWHSLKLFGLAMKMLV 487
Query: 277 PHLKAEGVSQMFYPAYAAAYRKSYMAATAL 188
P+LKAEGVSQM +PA AAAY KSYMAAT L
Sbjct: 488 PNLKAEGVSQMLFPANAAAYHKSYMAATTL 517
>sp|O65726|ERG12_BRANA Squalene monooxygenase 1,2 OS=Brassica napus GN=SQP1,2
PE=2 SV=1
Length = 518
Score = 334 bits (856), Expect = 4e-091
Identities = 166/210 (79%), Positives = 186/210 (88%)
Frame = -1
Query: 817 DEGAQIKTMPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLR 638
DEG+ IK KR+ ATLS K+GVIVLGDAFNMRHP IASGMMVLLSDILIL RLL+PL
Sbjct: 309 DEGSHIKITQAKRIPATLSRKKGVIVLGDAFNMRHPVIASGMMVLLSDILILSRLLKPLG 368
Query: 637 NLGDANKISEVIKSFYIIRKPMSATVNTLGNAFSQVLVASTDEAKEAMQQGCFDYLSSGG 458
NLGD NK+SEV+KSFY +RKPMSATVNTLGN+F QVL+ASTDEAKEAM+QGCFDYLSSGG
Sbjct: 369 NLGDENKVSEVMKSFYALRKPMSATVNTLGNSFWQVLIASTDEAKEAMRQGCFDYLSSGG 428
Query: 457 FRTSGMMALLGGMNPRPLSLIFHLCGITLSSIGQLLSPFPSPLRIWHSLRLFGLSMKMLI 278
FRTSG+MAL+GGMNPRPLSL +HL I+LSSIGQLLSPFP+PLR+WHSLRL LS+KML+
Sbjct: 429 FRTSGLMALIGGMNPRPLSLFYHLFVISLSSIGQLLSPFPTPLRVWHSLRLLDLSLKMLV 488
Query: 277 PHLKAEGVSQMFYPAYAAAYRKSYMAATAL 188
PHLKAEG+ QM P AAAYRKSYMAAT +
Sbjct: 489 PHLKAEGIGQMLSPTNAAAYRKSYMAATVV 518
>sp|O65727|ERG11_BRANA Squalene monooxygenase 1,1 OS=Brassica napus GN=SQP1,1
PE=2 SV=1
Length = 506
Score = 330 bits (844), Expect = 1e-089
Identities = 165/173 (95%), Positives = 170/173 (98%)
Frame = -1
Query: 817 DEGAQIKTMPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLR 638
DEGAQIK MPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMV+LSDILILRRLLQPLR
Sbjct: 308 DEGAQIKAMPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMVVLSDILILRRLLQPLR 367
Query: 637 NLGDANKISEVIKSFYIIRKPMSATVNTLGNAFSQVLVASTDEAKEAMQQGCFDYLSSGG 458
NL DANK+SEVIKSFY+IRKPMSATVNTLGNAFSQVL+ASTDEAKEAM+QGCFDYLSSGG
Sbjct: 368 NLSDANKVSEVIKSFYVIRKPMSATVNTLGNAFSQVLIASTDEAKEAMRQGCFDYLSSGG 427
Query: 457 FRTSGMMALLGGMNPRPLSLIFHLCGITLSSIGQLLSPFPSPLRIWHSLRLFG 299
FRTSGMMALLGGMNPRPLSLIFHLCGITLSSIGQLLSPFPSPL IWHSLRLFG
Sbjct: 428 FRTSGMMALLGGMNPRPLSLIFHLCGITLSSIGQLLSPFPSPLGIWHSLRLFG 480
>sp|O65403|ERG13_ARATH Squalene monooxygenase 2 OS=Arabidopsis thaliana GN=SQP2
PE=2 SV=1
Length = 516
Score = 268 bits (685), Expect = 3e-071
Identities = 130/206 (63%), Positives = 163/206 (79%)
Frame = -1
Query: 805 QIKTMPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLRNLGD 626
+IK+ TK M + L +K+GVIVLGDAFNMRHP IASGMMV LSDI ILR LL+PL NL +
Sbjct: 311 EIKSTATKSMSSRLCDKRGVIVLGDAFNMRHPIIASGMMVALSDICILRNLLKPLPNLSN 370
Query: 625 ANKISEVIKSFYIIRKPMSATVNTLGNAFSQVLVASTDEAKEAMQQGCFDYLSSGGFRTS 446
K+S+++KSFYIIRKPMSATVNTL + FSQVLVA+TDEA+E M+QGCF+YL+ G F+T
Sbjct: 371 TKKVSDLVKSFYIIRKPMSATVNTLASIFSQVLVATTDEAREGMRQGCFNYLARGDFKTR 430
Query: 445 GMMALLGGMNPRPLSLIFHLCGITLSSIGQLLSPFPSPLRIWHSLRLFGLSMKMLIPHLK 266
G+M +LGGMNP PL+L+ HL ITL+S+G LLSPFPSP R WHSLR+ +++ML HL
Sbjct: 431 GLMTILGGMNPHPLTLVLHLVAITLTSMGHLLSPFPSPRRFWHSLRILAWALQMLGAHLV 490
Query: 265 AEGVSQMFYPAYAAAYRKSYMAATAL 188
EG +M P AAAYR++Y+A T +
Sbjct: 491 DEGFKEMLIPTNAAAYRRNYIATTTV 516
>sp|O48651|ERG1_PANGI Squalene monooxygenase OS=Panax ginseng PE=2 SV=1
Length = 539
Score = 196 bits (497), Expect = 2e-049
Identities = 94/203 (46%), Positives = 138/203 (67%), Gaps = 1/203 (0%)
Frame = -1
Query: 817 DEGAQIKTMPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLR 638
D+G I+TMP + M A G ++LGDAFNMRHP GM V LSDI+++R LL+PLR
Sbjct: 334 DKG-NIRTMPNRSMPADPHPTPGALLLGDAFNMRHPLTGGGMTVALSDIVLIRDLLRPLR 392
Query: 637 NLGDANKISEVIKSFYIIRKPMSATVNTLGNAFSQVLVASTDEAKEAMQQGCFDYLSSGG 458
+L D++ + + ++SFY +RKP+++T+NTL A +V AS D+A++ M+ CFDYLS GG
Sbjct: 393 DLHDSSTLCKYLESFYTLRKPVASTINTLAGALYKVFCASPDKARQEMRNACFDYLSLGG 452
Query: 457 FRTSGMMALLGGMNPRPLSLIFHLCGITLSSIGQLLSPFPSPLRIWHSLRLFGLSMKMLI 278
+ G +ALL G+NPRP+SL H + + +G+LL PFPSP R+W RL + ++
Sbjct: 453 ICSQGPIALLSGLNPRPISLFLHFFAVAIYGVGRLLIPFPSPKRMWLGARLILGASGIIF 512
Query: 277 PHLKAEGVSQMFYPAYAAAYRKS 209
P +K+EG+ QMF+PA AY ++
Sbjct: 513 PIIKSEGLRQMFFPAIVPAYYRA 535
>sp|Q14534|ERG1_HUMAN Squalene monooxygenase OS=Homo sapiens GN=SQLE PE=2 SV=3
Length = 574
Score = 97 bits (239), Expect = 2e-019
Identities = 54/152 (35%), Positives = 87/152 (57%), Gaps = 2/152 (1%)
Frame = -1
Query: 814 EGAQIKTMPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLRN 635
+ + +++MP + + +K+GV++LGDA+NMRHP GM V DI + R+LL+ + +
Sbjct: 381 DNSHLRSMPASFLPPSSVKKRGVLLLGDAYNMRHPLTGGGMTVAFKDIKLWRKLLKGIPD 440
Query: 634 LGDANKISEVIKSFYIIRKPM-SATVNTLGNAFSQVLVASTDEAKEAMQQGCFDYLSSGG 458
L D I E KSFY RK S VN L A + L ++TD++ +++ CF Y GG
Sbjct: 441 LYDDAAIFEAKKSFYWARKTSHSFVVNILAQALYE-LFSATDDSLHQLRKACFLYFKLGG 499
Query: 457 FRTSGMMALLGGMNPRPLSLIFHLCGITLSSI 362
+G + LL ++P PL LI H + + ++
Sbjct: 500 ECVAGPVGLLSVLSPNPLVLIGHFFAVAIYAV 531
>sp|Q9C1W3|ERG1_SCHPO Probable squalene monooxygenase OS=Schizosaccharomyces
pombe GN=SPBC713.12 PE=2 SV=1
Length = 457
Score = 96 bits (236), Expect = 3e-019
Identities = 59/187 (31%), Positives = 99/187 (52%), Gaps = 6/187 (3%)
Frame = -1
Query: 805 QIKTMPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQP--LRNL 632
++++MP + + T++ +G+I++GD+ NMRHP GM V D +L R + P + +L
Sbjct: 269 RLRSMPNQFLPPTVNRTKGMILVGDSNNMRHPLTGGGMTVCFHDAYLLSRFISPSAVPDL 328
Query: 631 GDANKISEVIKSFYIIRKPMSATVNTLGNAFSQVLVASTDEAKEAMQQGCFDYLSSGGFR 452
D +I + F+ RK S +N L A + L + +A++ GC DY GG
Sbjct: 329 LDYERILNQMNKFHWKRKGYSFVINVLSIALYK-LFTPKNRYMKALESGCIDYFKRGGNC 387
Query: 451 TSGMMALLGGMNPRPLSLIFHLCGITLSSIGQLLSPFPS---PLRIWHSLRLFGLSMKML 281
G + LLGG++ P LI H + L I Q + P+ P+RI SL +F + ++
Sbjct: 388 VEGPIRLLGGLDHSPSHLIGHFYAVCLYGIYQYVLSGPALLMPVRIIESLLIFLQASLVI 447
Query: 280 IPHLKAE 260
IP++ +E
Sbjct: 448 IPYILSE 454
>sp|P52019|ERG1_MOUSE Squalene monooxygenase OS=Mus musculus GN=Sqle PE=2 SV=1
Length = 572
Score = 95 bits (234), Expect = 6e-019
Identities = 53/149 (35%), Positives = 85/149 (57%), Gaps = 2/149 (1%)
Frame = -1
Query: 814 EGAQIKTMPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLRN 635
+ +++TMP + + K+GV++LGDA+N+RHP GM V L DI + R+LL+ + +
Sbjct: 379 QNGRLRTMPASFLPPSSVNKRGVLILGDAYNLRHPLTGGGMTVALKDIKLWRQLLKDIPD 438
Query: 634 LGDANKISEVIKSFYIIRK-PMSATVNTLGNAFSQVLVASTDEAKEAMQQGCFDYLSSGG 458
L D I + KSF+ RK S VN L A + L ++TD++ +++ CF Y GG
Sbjct: 439 LYDDAAIFQAKKSFFWSRKRTHSFVVNVLAQALYE-LFSATDDSLHQLRKACFLYFKLGG 497
Query: 457 FRTSGMMALLGGMNPRPLSLIFHLCGITL 371
+G + LL ++P PL LI H + +
Sbjct: 498 ECVTGPVGLLSILSPHPLVLIRHFFSVAI 526
>sp|P52020|ERG1_RAT Squalene monooxygenase OS=Rattus norvegicus GN=Sqle PE=2
SV=1
Length = 573
Score = 95 bits (234), Expect = 6e-019
Identities = 55/149 (36%), Positives = 86/149 (57%), Gaps = 2/149 (1%)
Frame = -1
Query: 814 EGAQIKTMPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLRN 635
+ A+++TMP + + K+GV++LGDA+N+RHP GM V L DI I R+LL+ + +
Sbjct: 380 QNARLRTMPASFLPPSSVNKRGVLLLGDAYNLRHPLTGGGMTVALKDIKIWRQLLKDIPD 439
Query: 634 LGDANKISEVIKSFYIIRK-PMSATVNTLGNAFSQVLVASTDEAKEAMQQGCFDYLSSGG 458
L D I + KSF+ RK S VN L A + L ++TD++ +++ CF Y GG
Sbjct: 440 LYDDAAIFQAKKSFFWSRKRSHSFVVNVLAQALYE-LFSATDDSLRQLRKACFLYFKLGG 498
Query: 457 FRTSGMMALLGGMNPRPLSLIFHLCGITL 371
+G + LL ++P PL LI H + +
Sbjct: 499 ECLTGPVGLLSILSPDPLLLIRHFFSVAV 527
>sp|Q92206|ERG1_CANAL Squalene monooxygenase OS=Candida albicans GN=ERG1 PE=3
SV=1
Length = 496
Score = 84 bits (205), Expect = 1e-015
Identities = 50/153 (32%), Positives = 80/153 (52%), Gaps = 6/153 (3%)
Frame = -1
Query: 805 QIKTMPTKRMEAT---LSEKQGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQP--L 641
+ + MP + + A +G I+LGD+ NMRHP GM V L+D ++L +LL P +
Sbjct: 305 KFRIMPNQYLSAMKQGSENHKGFILLGDSLNMRHPLTGGGMTVGLNDSVLLAKLLHPKFV 364
Query: 640 RNLGDANKISEVIKSFYIIRKPMSATVNTLGNAFSQVLVASTDEAKEAMQQGCFDYLSSG 461
+ D I++ +K+F+ RK + A +NTL + L A+ + ++ GCF Y G
Sbjct: 365 EDFDDHQLIAKRLKTFHRKRKNLDAVINTLSISLYS-LFAADKKPLRILRNGCFKYFQRG 423
Query: 460 GFRTSGMMALLGGMNPRPLSLIFHLCGITLSSI 362
G +G + LL GM P P+ L H + S+
Sbjct: 424 GECVNGPIGLLSGMLPFPMLLFNHFFSVAFYSV 456
>sp|P32476|ERG1_YEAST Squalene monooxygenase OS=Saccharomyces cerevisiae GN=ERG1
PE=1 SV=2
Length = 496
Score = 82 bits (201), Expect = 4e-015
Identities = 44/136 (32%), Positives = 72/136 (52%), Gaps = 2/136 (1%)
Frame = -1
Query: 805 QIKTMPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLRNLGD 626
+ + MP + A ++ G+ V+GDA NMRHP GM V L D+++L + + L + D
Sbjct: 311 KFRAMPNSYLPARQNDVTGMCVIGDALNMRHPLTGGGMTVGLHDVVLLIKKIGDL-DFSD 369
Query: 625 ANKISEVIKSFYIIRKPMSATVNTLGNAFSQVLVASTDEAKEAMQQGCFDYLSSGGFRTS 446
K+ + + ++ RK + +N L A + A +D K A+Q+GCF Y GG +
Sbjct: 370 REKVLDELLDYHFERKSYDSVINVLSVALYSLFAADSDNLK-ALQKGCFKYFQRGGDCVN 428
Query: 445 GMMALLGGMNPRPLSL 398
+ L G+ P+PL L
Sbjct: 429 KPVEFLSGVLPKPLQL 444
>sp|O13306|ERG1_CANGA Squalene monooxygenase OS=Candida glabrata GN=ERG1 PE=3
SV=2
Length = 489
Score = 78 bits (190), Expect = 7e-014
Identities = 45/136 (33%), Positives = 72/136 (52%), Gaps = 2/136 (1%)
Frame = -1
Query: 805 QIKTMPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLRNLGD 626
+ K M + A ++ G+ V+GDA NMRHP GM V L+D+++L + + L + D
Sbjct: 304 KFKPMANSWLPARQNDVTGLCVIGDALNMRHPLTGGGMTVGLNDVVLLIKKIGDL-DFSD 362
Query: 625 ANKISEVIKSFYIIRKPMSATVNTLGNAFSQVLVASTDEAKEAMQQGCFDYLSSGGFRTS 446
K+ + + ++ RK A VN L + + A + K A+Q+GCF Y GG +
Sbjct: 363 REKVLDELLDYHFERKNYDAVVNVLSISLYSLFAADSKNLK-ALQKGCFKYFQRGGDCVN 421
Query: 445 GMMALLGGMNPRPLSL 398
+A L G+ P+PL L
Sbjct: 422 LPVAFLAGVLPKPLLL 437
>sp|Q75F69|ERG1_ASHGO Squalene monooxygenase OS=Ashbya gossypii GN=ERG1 PE=3
SV=1
Length = 497
Score = 73 bits (178), Expect = 2e-012
Identities = 45/151 (29%), Positives = 74/151 (49%), Gaps = 2/151 (1%)
Frame = -1
Query: 814 EGAQIKTMPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMVLLSDILILRRLLQPLRN 635
E K MP + A+ + G+ V+GDA NMRHP GM V L D+++L + + + +
Sbjct: 309 ESKSYKCMPNSWLPASQNNVTGLCVVGDALNMRHPLTGGGMAVGLMDVVLLVKTIGDM-D 367
Query: 634 LGDANKISEVIKSFYIIRKPMSATVNTLGNAFSQVLVASTDEAKEAMQQGCFDYLSSGGF 455
D ++ + F+ RK + +NTL A + A + K+ +Q+GCF+YL G
Sbjct: 368 FSDREEVLNELLGFHYERKAHACVINTLSIALYSLFAADSYYLKK-LQKGCFEYLGRGED 426
Query: 454 RTSGMMALLGGMNPRPLSLIFHLCGITLSSI 362
++ L G+ P P L + L S+
Sbjct: 427 WVRQPISFLSGVLPSPYLLTKVFFTVALYSV 457
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98,767,994,010
Number of Sequences: 518415
Number of Extensions: 98767994010
Number of Successful Extensions: 632508636
Number of sequences better than 0.0: 0
|
