BLASTX 7.6.2
Query= UN24156 /QuerySize=1524
(1523 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q39227|SMT2_ARATH 24-methylenesterol C-methyltransferase 2 OS... 690 1e-197
sp|Q94JS4|SMT3B_ARATH 24-methylenesterol C-methyltransferase 3 O... 631 5e-180
sp|O82427|SMT2_ORYSJ 24-methylenesterol C-methyltransferase 2 OS... 534 7e-151
sp|Q6ZIX2|SMT1_ORYSJ Cycloartenol-C-24-methyltransferase 1 OS=Or... 238 1e-061
sp|Q9LM02|SMT1_ARATH Cycloartenol-C-24-methyltransferase OS=Arab... 237 2e-061
sp|Q54I98|SMT1_DICDI Probable cycloartenol-C-24-methyltransferas... 223 3e-057
sp|Q6C2D9|ERG6_YARLI Sterol 24-C-methyltransferase OS=Yarrowia l... 220 3e-056
sp|Q6BRB7|ERG6_DEBHA Sterol 24-C-methyltransferase OS=Debaryomyc... 218 1e-055
sp|O74198|ERG6_CANAL Sterol 24-C-methyltransferase OS=Candida al... 213 3e-054
sp|Q6FRZ7|ERG6_CANGA Sterol 24-C-methyltransferase OS=Candida gl... 212 6e-054
sp|Q6CYB3|ERG6_KLULA Sterol 24-C-methyltransferase OS=Kluyveromy... 212 6e-054
sp|O14321|ERG6_SCHPO Sterol 24-C-methyltransferase OS=Schizosacc... 212 8e-054
sp|Q875K1|ERG6_CLAL4 Sterol 24-C-methyltransferase OS=Clavispora... 211 2e-053
sp|Q96WX4|ERG6_PNECA Sterol 24-C-methyltransferase OS=Pneumocyst... 210 4e-053
sp|P25087|ERG6_YEAST Sterol 24-C-methyltransferase OS=Saccharomy... 210 4e-053
sp|Q5EN22|ERG6_MAGGR Sterol 24-C-methyltransferase OS=Magnaporth... 208 1e-052
sp|Q9P3R1|ERG6_NEUCR Sterol 24-C-methyltransferase OS=Neurospora... 202 8e-051
sp|Q759S7|ERG6_ASHGO Sterol 24-C-methyltransferase OS=Ashbya gos... 197 2e-049
sp|Q9ZSK1|GTOMC_ARATH Tocopherol O-methyltransferase, chloroplas... 72 7e-012
sp|Q9C6B9|PEAM3_ARATH Putative phosphoethanolamine N-methyltrans... 72 1e-011
>sp|Q39227|SMT2_ARATH 24-methylenesterol C-methyltransferase 2 OS=Arabidopsis
thaliana GN=SMT2 PE=1 SV=2
Length = 361
Score = 690 bits (1779), Expect = 1e-197
Identities = 331/356 (92%), Positives = 346/356 (97%)
Frame = +3
Query: 48 MDSVALFFTGALVAGGIYWFLCVLGPAECKGKRALDLSGGSISAEKVEDNYKQYWSFFRR 227
MDS+ LFFTGALVA GIYWFLCVLGPAE KGKRA+DLSGGSISAEKV+DNYKQYWSFFRR
Sbjct: 1 MDSLTLFFTGALVAVGIYWFLCVLGPAERKGKRAVDLSGGSISAEKVQDNYKQYWSFFRR 60
Query: 228 PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQ 407
PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSI GKSH+DATRLHEEMAVDLIQ
Sbjct: 61 PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIPGKSHKDATRLHEEMAVDLIQ 120
Query: 408 VKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCG 587
VKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQV RAR HN+KAGLDALCEVVCG
Sbjct: 121 VKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVNRARLHNKKAGLDALCEVVCG 180
Query: 588 NFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENE 767
NFLQMPFDDN+FDGAYSIEATCHAPKLEEVYAEIYRVLKPGS+YVSYEWVTT+KF AE++
Sbjct: 181 NFLQMPFDDNSFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSMYVSYEWVTTEKFKAEDD 240
Query: 768 EHVEVIQGIERGDALPGLRAYSDIAETAKKVGFEVVKEKDLAAPPAEPWWTRLKMGRLAY 947
EHVEVIQGIERGDALPGLRAY DIAETAKKVGFE+VKEKDLA+PPAEPWWTRLKMGRLAY
Sbjct: 241 EHVEVIQGIERGDALPGLRAYVDIAETAKKVGFEIVKEKDLASPPAEPWWTRLKMGRLAY 300
Query: 948 WRNHIVVQVLSAVGVAPKGTVDVHEMLFKTADFLSRGGETEIFSPMHMILCRKPTS 1115
WRNHIVVQ+LSAVGVAPKGTVDVHEMLFKTAD+L+RGGET IFSPMHMILCRKP S
Sbjct: 301 WRNHIVVQILSAVGVAPKGTVDVHEMLFKTADYLTRGGETGIFSPMHMILCRKPES 356
>sp|Q94JS4|SMT3B_ARATH 24-methylenesterol C-methyltransferase 3 OS=Arabidopsis
thaliana GN=SMT3 PE=2 SV=1
Length = 359
Score = 631 bits (1626), Expect = 5e-180
Identities = 292/354 (82%), Positives = 331/354 (93%)
Frame = +3
Query: 48 MDSVALFFTGALVAGGIYWFLCVLGPAECKGKRALDLSGGSISAEKVEDNYKQYWSFFRR 227
MDSVAL+ T L+AG +YWF+CVLGPAE KGKRA DLSGGSISAEKV+DNY QYWSFFR+
Sbjct: 1 MDSVALYCTAGLIAGAVYWFICVLGPAERKGKRASDLSGGSISAEKVKDNYNQYWSFFRK 60
Query: 228 PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQ 407
PKEIE+AEKVPDFVDTFYNLVTDIYEWGWGQSFHFSP + GKS +DATR+HEEMAVDLI+
Sbjct: 61 PKEIESAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPHVPGKSDKDATRIHEEMAVDLIK 120
Query: 408 VKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCG 587
VKPGQKILD GCGVGGPMRAIA+HS+A V GITINEYQV+RA+ HN+KAGLD+LC VVCG
Sbjct: 121 VKPGQKILDAGCGVGGPMRAIAAHSKAQVTGITINEYQVQRAKLHNKKAGLDSLCNVVCG 180
Query: 588 NFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENE 767
NFL+MPFD+NTFDGAYSIEATCHAPKLEEVY+EI+RV+KPGSL+VSYEWVTT+K+ ++E
Sbjct: 181 NFLKMPFDENTFDGAYSIEATCHAPKLEEVYSEIFRVMKPGSLFVSYEWVTTEKYRDDDE 240
Query: 768 EHVEVIQGIERGDALPGLRAYSDIAETAKKVGFEVVKEKDLAAPPAEPWWTRLKMGRLAY 947
EH +VIQGIERGDALPGLR+Y+DIA TAKKVGFEVVKEKDLA PP++PWW RLKMGR+AY
Sbjct: 241 EHKDVIQGIERGDALPGLRSYADIAVTAKKVGFEVVKEKDLAKPPSKPWWNRLKMGRIAY 300
Query: 948 WRNHIVVQVLSAVGVAPKGTVDVHEMLFKTADFLSRGGETEIFSPMHMILCRKP 1109
WRNH+VV +LSA+GVAPKGTVDVH+MLFKTAD+L+RGGET IFSPMHMILCRKP
Sbjct: 301 WRNHVVVVILSAIGVAPKGTVDVHKMLFKTADYLTRGGETGIFSPMHMILCRKP 354
>sp|O82427|SMT2_ORYSJ 24-methylenesterol C-methyltransferase 2 OS=Oryza sativa
subsp. japonica GN=Smt2-1 PE=2 SV=2
Length = 363
Score = 534 bits (1375), Expect = 7e-151
Identities = 253/359 (70%), Positives = 297/359 (82%), Gaps = 5/359 (1%)
Frame = +3
Query: 48 MDSVALFFTGALVAGG-IYWFLCVLGPAECKGKRALDLSGGSISAEKVEDNYKQYWSFFR 224
M++ + +T A V +YWF+ V+G AE KGKRA+DL GSI+ +KV+D Y QYWSFFR
Sbjct: 1 MEAATMAWTAAGVGMALVYWFVWVMGAAEVKGKRAVDLKMGSITNDKVKDKYTQYWSFFR 60
Query: 225 RPKEIET----AEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMA 392
RPKE T AEKVP FVDTFYNLVTDIYEWGWGQSFHFSPS+ G+SHR+ATR+HEE
Sbjct: 61 RPKETATTEASAEKVPAFVDTFYNLVTDIYEWGWGQSFHFSPSLPGRSHREATRVHEERV 120
Query: 393 VDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALC 572
DL+Q KPG ++LDVGCGVGGPMRAIA+HS +NVVGITINEYQV RAR HNRKAGLD+ C
Sbjct: 121 ADLLQAKPGHRLLDVGCGVGGPMRAIAAHSGSNVVGITINEYQVNRARAHNRKAGLDSRC 180
Query: 573 EVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKF 752
EVVCGNFL MPF D +FDGAYSIEATCHAP+L++VY E++RVLKPG LYVSYEWVTT +
Sbjct: 181 EVVCGNFLSMPFSDASFDGAYSIEATCHAPRLQDVYGEVFRVLKPGGLYVSYEWVTTSLY 240
Query: 753 NAENEEHVEVIQGIERGDALPGLRAYSDIAETAKKVGFEVVKEKDLAAPPAEPWWTRLKM 932
A+N EHVE I GIERGDALPGLR +IA AK+VGFEV+KE DLA PPA PWWTRLKM
Sbjct: 241 RADNPEHVEAIHGIERGDALPGLRRQDEIASIAKEVGFEVLKELDLALPPALPWWTRLKM 300
Query: 933 GRLAYWRNHIVVQVLSAVGVAPKGTVDVHEMLFKTADFLSRGGETEIFSPMHMILCRKP 1109
GR+AYWRN +VV+VL+ + +APKG +VHEML++TA L+RGGET IF+PMHM+L RKP
Sbjct: 301 GRIAYWRNSLVVRVLTMLRIAPKGVCEVHEMLYETAQHLTRGGETGIFTPMHMVLLRKP 359
>sp|Q6ZIX2|SMT1_ORYSJ Cycloartenol-C-24-methyltransferase 1 OS=Oryza sativa
subsp. japonica GN=Smt1-1 PE=2 SV=1
Length = 344
Score = 238 bits (605), Expect = 1e-061
Identities = 118/272 (43%), Positives = 164/272 (60%), Gaps = 7/272 (2%)
Frame = +3
Query: 147 ALDLS---GGSISAEKVE---DNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEW 308
A+DL+ GG I+ ++V+ D Y++Y ++ KE D V+ +Y+L T YE+
Sbjct: 6 AMDLASGLGGKITKDEVKSAVDEYEKYHGYY-GGKEEARKSNYTDMVNKYYDLATSFYEY 64
Query: 309 GWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRA 488
GWG+SFHF+ G+S R++ + HE + VKPG K+LDVGCG+GGP+R IA S A
Sbjct: 65 GWGESFHFAHRWNGESLRESIKRHEHFLALQLGVKPGMKVLDVGCGIGGPLREIAKFSLA 124
Query: 489 NVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKL 668
+V G+ NEYQ+ R ++ NR AG+ C+ V +F++MPF DNTFD Y+IEATCHAP
Sbjct: 125 SVTGLNNNEYQITRGKELNRVAGVSGTCDFVKADFMKMPFSDNTFDAVYAIEATCHAPDP 184
Query: 669 EEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAET 848
Y EIYRVLKPG + YEW TD + N H + IE G+ LP +R+ +
Sbjct: 185 VGCYKEIYRVLKPGQCFAVYEWCITDHYEPNNATHKRIKDEIELGNGLPDIRSTQQCLQA 244
Query: 849 AKKVGFEVVKEKDLAAPPAEPWWTRLKMGRLA 944
AK GFEV+ +KDLA PW+ L R +
Sbjct: 245 AKDAGFEVIWDKDLAEDSPVPWYLPLDPSRFS 276
>sp|Q9LM02|SMT1_ARATH Cycloartenol-C-24-methyltransferase OS=Arabidopsis
thaliana GN=SMT1 PE=2 SV=1
Length = 336
Score = 237 bits (603), Expect = 2e-061
Identities = 116/258 (44%), Positives = 158/258 (61%), Gaps = 4/258 (1%)
Frame = +3
Query: 162 GGSISAEKV---EDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHF 332
GG I V + Y+QY F E E D V+ +Y+L T YE+GWG+SFHF
Sbjct: 8 GGKIDKSDVLTAVEKYEQY-HVFHGGNEEERKANYTDMVNKYYDLATSFYEYGWGESFHF 66
Query: 333 SPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVVGITIN 512
+ +G+S R++ + HE + ++PGQK+LDVGCG+GGP+R IA S + V G+ N
Sbjct: 67 AQRWKGESLRESIKRHEHFLALQLGIQPGQKVLDVGCGIGGPLREIARFSNSVVTGLNNN 126
Query: 513 EYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIY 692
EYQ+ R ++ NR AG+D C V +F++MPF +N+FD Y+IEATCHAP Y EIY
Sbjct: 127 EYQITRGKELNRLAGVDKTCNFVKADFMKMPFPENSFDAVYAIEATCHAPDAYGCYKEIY 186
Query: 693 RVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAETAKKVGFEV 872
RVLKPG + +YEW TD F+ +N EH ++ IE GD LP +R + E K+ GFEV
Sbjct: 187 RVLKPGQCFAAYEWCMTDAFDPDNAEHQKIKGEIEIGDGLPDIRLTTKCLEALKQAGFEV 246
Query: 873 VKEKDLAAPPAEPWWTRL 926
+ EKDLA PW+ L
Sbjct: 247 IWEKDLAKDSPVPWYLPL 264
>sp|Q54I98|SMT1_DICDI Probable cycloartenol-C-24-methyltransferase 1
OS=Dictyostelium discoideum GN=smt1 PE=1 SV=1
Length = 354
Score = 223 bits (568), Expect = 3e-057
Identities = 111/255 (43%), Positives = 155/255 (60%), Gaps = 3/255 (1%)
Frame = +3
Query: 180 EKVEDNYKQYWSFFR--RPKEIETAE-KVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRG 350
+KV+D Y F+ K I+ + V+TFY+L TD YE+GWGQSFHF+ +
Sbjct: 30 DKVDDTLNGYKELFKGNDDKAIQARKNNYTHMVNTFYDLATDFYEFGWGQSFHFATRHKY 89
Query: 351 KSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKR 530
+S + HE + + PG K++D+GCGVGGPMR IA S ANVVG+ NEYQ++R
Sbjct: 90 ESFEASIARHEMYMAHQLGLFPGMKVIDIGCGVGGPMRTIARFSGANVVGLNNNEYQIQR 149
Query: 531 ARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPG 710
+ N AGL LC + +F+ +P +DNT+D AY IEATCHAP L +Y E++R++KPG
Sbjct: 150 GKRLNESAGLSHLCSFIKADFMHVPVEDNTYDCAYQIEATCHAPDLVGLYKEVFRIVKPG 209
Query: 711 SLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAETAKKVGFEVVKEKDL 890
L+ YEW+ T+KFN E+ V + + IE G+ LP L ++I AK GFEV+ D+
Sbjct: 210 GLFGGYEWIMTNKFNPEDPVEVNIKKQIELGNGLPDLVKPAEIINAAKAAGFEVITAFDV 269
Query: 891 AAPPAEPWWTRLKMG 935
A PW+ L G
Sbjct: 270 AETSELPWYLPLSSG 284
>sp|Q6C2D9|ERG6_YARLI Sterol 24-C-methyltransferase OS=Yarrowia lipolytica
GN=ERG6 PE=3 SV=1
Length = 381
Score = 220 bits (559), Expect = 3e-056
Identities = 104/215 (48%), Positives = 143/215 (66%), Gaps = 1/215 (0%)
Frame = +3
Query: 276 FYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGG 455
+YNLVTD YE+GWG SFHFS +G++ R AT HE + ++PG K+LDVGCGVGG
Sbjct: 82 YYNLVTDFYEYGWGSSFHFSRYYKGEAFRQATARHEHYLAYKMGIQPGMKVLDVGCGVGG 141
Query: 456 PMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAY 635
P R IA + AN+VG+ N+YQV+R ++ G V G+F+QM F DN+FD Y
Sbjct: 142 PAREIARFTGANIVGLNNNDYQVERGTHYSEVQGFGDQVTYVKGDFMQMDFPDNSFDAVY 201
Query: 636 SIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALP 815
+IEAT HAP LE VY+EI+RVLKPG ++ YEWV TD+++ N EH ++ GIE+GD +P
Sbjct: 202 AIEATVHAPVLEGVYSEIFRVLKPGGVFGVYEWVMTDEYDESNPEHRDICYGIEKGDGIP 261
Query: 816 GLRAYSDIAETAKKVGFEVVKEKDLAAPPAE-PWW 917
+ + + VGF++ ++DLAA AE PW+
Sbjct: 262 KMYKREVAVKALENVGFDIEYQEDLAADDAEVPWY 296
>sp|Q6BRB7|ERG6_DEBHA Sterol 24-C-methyltransferase OS=Debaryomyces hansenii
GN=ERG6 PE=3 SV=1
Length = 377
Score = 218 bits (553), Expect = 1e-055
Identities = 113/262 (43%), Positives = 156/262 (59%), Gaps = 3/262 (1%)
Frame = +3
Query: 138 GKRALDLSGGSISAEKVEDNYKQYW-SFFRRPKEIETAEKVPDFVDTFYNLVTDIYEWGW 314
G +AL +S ++E D Y ++W + E + + +YNLVTD YE+GW
Sbjct: 31 GLKAL-MSKARDASEVANDGYFKHWDGGVTKEDEDKRLSDYSNLTAHYYNLVTDFYEYGW 89
Query: 315 GQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANV 494
G SFHFS G++ R AT HE +Q+ K+LDVGCGVGGP R I + ++
Sbjct: 90 GSSFHFSRYYTGEAFRQATARHEHFLAHKMQINENMKVLDVGCGVGGPAREICRFTDCSI 149
Query: 495 VGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEE 674
VG+ N+YQ++RA + RK LD V G+F+QM F+ +FD Y+IEAT HAP LE
Sbjct: 150 VGLNNNDYQIERANHYARKYKLDDKLSFVKGDFMQMDFEAESFDAVYAIEATVHAPVLEG 209
Query: 675 VYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAETAK 854
VY+EIY+VLKPG ++ YEWV TDK++ ENEEH ++ GIE GD +P + + K
Sbjct: 210 VYSEIYKVLKPGGVFGVYEWVMTDKYDDENEEHRKIAYGIEVGDGIPKMYKREVAEKALK 269
Query: 855 KVGFEVVKEKDLAAPPAE-PWW 917
VGFE+ E DLA + PW+
Sbjct: 270 SVGFEIEYEADLADKEDDIPWY 291
>sp|O74198|ERG6_CANAL Sterol 24-C-methyltransferase OS=Candida albicans GN=ERG6
PE=3 SV=1
Length = 376
Score = 213 bits (541), Expect = 3e-054
Identities = 108/261 (41%), Positives = 150/261 (57%), Gaps = 1/261 (0%)
Frame = +3
Query: 138 GKRALDLSGGSISAEKVEDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEWGWG 317
G AL ++ E +K + + E + +YNLVTD YE+GWG
Sbjct: 30 GLSALIAKSKDAASVAAEGYFKHWDGGISKDDEEKRLNDYSQLTHHYYNLVTDFYEYGWG 89
Query: 318 QSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVV 497
SFHFS +G++ R AT HE + + K+LDVGCGVGGP R I + +V
Sbjct: 90 SSFHFSRYYKGEAFRQATARHEHFLAHKMNLNENMKVLDVGCGVGGPGREITRFTDCEIV 149
Query: 498 GITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEV 677
G+ N+YQ++RA + +K LD V G+F+QM F+ +FD Y+IEAT HAP LE V
Sbjct: 150 GLNNNDYQIERANHYAKKYHLDHKLSYVKGDFMQMDFEPESFDAVYAIEATVHAPVLEGV 209
Query: 678 YAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAETAKK 857
Y+EIY+VLKPG ++ YEWV TDK++ NEEH ++ GIE GD +P + + + K
Sbjct: 210 YSEIYKVLKPGGIFGVYEWVMTDKYDETNEEHRKIAYGIEVGDGIPKMYSRKVAEQALKN 269
Query: 858 VGFEVVKEKDLAAPPAE-PWW 917
VGFE+ +KDLA E PW+
Sbjct: 270 VGFEIEYQKDLADVDDEIPWY 290
>sp|Q6FRZ7|ERG6_CANGA Sterol 24-C-methyltransferase OS=Candida glabrata GN=ERG6
PE=3 SV=1
Length = 372
Score = 212 bits (539), Expect = 6e-054
Identities = 107/257 (41%), Positives = 153/257 (59%), Gaps = 4/257 (1%)
Frame = +3
Query: 156 LSGGSISAEKVEDNYKQYWSFFRRPKEIE--TAEKVPDFVDTFYNLVTDIYEWGWGQSFH 329
LS + + Y ++W + KE E E + ++YN+VTD YE+GWG SFH
Sbjct: 32 LSKNRNAQREAVSKYLRHWD-GKTDKEAEDRRLEDYNEATHSYYNVVTDFYEYGWGSSFH 90
Query: 330 FSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVVGITI 509
FS +G++ + A HE+ + +K G +LDVGCGVGGP R IA + N++G+
Sbjct: 91 FSRFYKGENFQAAMARHEQYLAYMAGIKKGDLVLDVGCGVGGPARTIARFTGCNIIGLNN 150
Query: 510 NEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEI 689
N+YQ+++A+ + +K L + V G+F+ M F+ N+FD Y+IEATCHAPKLE VY EI
Sbjct: 151 NDYQIQKAKYYAKKYNLQDHMDFVKGDFMNMEFEPNSFDKVYAIEATCHAPKLEGVYGEI 210
Query: 690 YRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAETAKKVGFE 869
Y+VLKPG + YEWV T+ ++ NEEH ++ IE GD +P + + K VGFE
Sbjct: 211 YKVLKPGGTFAVYEWVMTENYDENNEEHRKIAYEIELGDGIPKMFTVDVAKQALKNVGFE 270
Query: 870 VVKEKDLAAPPAE-PWW 917
V KDLA E PW+
Sbjct: 271 VEVSKDLADEDDEIPWY 287
>sp|Q6CYB3|ERG6_KLULA Sterol 24-C-methyltransferase OS=Kluyveromyces lactis
GN=ERG6 PE=3 SV=1
Length = 371
Score = 212 bits (539), Expect = 6e-054
Identities = 108/264 (40%), Positives = 150/264 (56%), Gaps = 1/264 (0%)
Frame = +3
Query: 138 GKRALDLSGGSISAEKVEDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEWGWG 317
G AL S E V K + E E + ++YN+VTD YE+GWG
Sbjct: 27 GFSALVSKNKSAQTEAVAKYLKHWDGKTDADAERRRLEDYNESTHSYYNVVTDFYEYGWG 86
Query: 318 QSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVV 497
SFHFS +G+S + HE +K ILDVGCGVGGP R I+ + N++
Sbjct: 87 SSFHFSRFFKGESFSASVARHEHYLAYKAGIKENDLILDVGCGVGGPARTISRFTGCNII 146
Query: 498 GITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEV 677
G+ N+YQ+++A + ++ LD+ V G+F++M FD+NTFD Y+IEATCHAP E V
Sbjct: 147 GLNNNDYQIQKANYYAKRDHLDSKLSFVKGDFMKMEFDENTFDSVYAIEATCHAPTFEGV 206
Query: 678 YAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAETAKK 857
Y EIY+VLKPG + YEWV TDK++ N EH ++ IE GD +P + + + K
Sbjct: 207 YGEIYKVLKPGGTFAVYEWVMTDKYDETNPEHRKIAYEIELGDGIPKMYSVDAARDALSK 266
Query: 858 VGFEVVKEKDLAAPPAE-PWWTRL 926
VGFE+++E DLA E PW+ L
Sbjct: 267 VGFEILEENDLADNDDEIPWYAPL 290
>sp|O14321|ERG6_SCHPO Sterol 24-C-methyltransferase OS=Schizosaccharomyces pombe
GN=SPBC16E9.05 PE=2 SV=1
Length = 378
Score = 212 bits (538), Expect = 8e-054
Identities = 112/273 (41%), Positives = 159/273 (58%), Gaps = 13/273 (4%)
Frame = +3
Query: 138 GKRALDLSGGSISAEKVED----NYKQYWSFFRRPKEIETAEK-------VPDFVDTFYN 284
GK A +G + A K D ++Y+ F+ R E E+ E V+++Y+
Sbjct: 21 GKAAEKKTGLAAIASKDVDEQSRKLQEYFEFWDRNHENESEEDRARRIDGYKSVVNSYYD 80
Query: 285 LVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMR 464
L TD+YE+GW QSFHFS +G++ + HE + +KPG ++LDVGCGVGGP R
Sbjct: 81 LATDLYEYGWSQSFHFSRFYKGEAFAQSIARHEHYLAYRMGIKPGSRVLDVGCGVGGPAR 140
Query: 465 AIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIE 644
I + N+VG+ N+YQ+ R ++ K LD V G+F+ MPF+DNTFD Y+IE
Sbjct: 141 EITEFTGCNLVGLNNNDYQISRCNNYAVKRNLDKKQVFVKGDFMHMPFEDNTFDYVYAIE 200
Query: 645 ATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLR 824
AT HAP LE VY EI+RVLKPG ++ YEWV +D +++ +H E+ IE GD +P +
Sbjct: 201 ATVHAPSLEGVYGEIFRVLKPGGVFGVYEWVMSDDYDSSIPKHREIAYNIEVGDGIPQMV 260
Query: 825 AYSDIAETAKKVGFEVVKEKDLA--APPAEPWW 917
D E KKVGF +++E DL P PW+
Sbjct: 261 RKCDAVEAIKKVGFNLLEEDDLTDHDNPDLPWY 293
>sp|Q875K1|ERG6_CLAL4 Sterol 24-C-methyltransferase OS=Clavispora lusitaniae
(strain ATCC 42720) GN=ERG6 PE=3 SV=1
Length = 375
Score = 211 bits (535), Expect = 2e-053
Identities = 102/215 (47%), Positives = 138/215 (64%), Gaps = 1/215 (0%)
Frame = +3
Query: 276 FYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGG 455
+YNLVTD YE+GWG SFHFS +G++ R AT HE + + ++LDVGCGVGG
Sbjct: 76 YYNLVTDFYEYGWGSSFHFSRYYKGEAFRQATARHEHFLAHKMNINENMRVLDVGCGVGG 135
Query: 456 PMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAY 635
P R I + +VG+ N+YQV+RA+ + +K LD V G+F+QM F+ +FD Y
Sbjct: 136 PGREICRFTDCTIVGLNNNDYQVERAQYYAKKYKLDDKLSYVKGDFMQMDFEPESFDAVY 195
Query: 636 SIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALP 815
+IEAT HAP LE VY+EIY+VLKPG ++ YEWV TDK++ NEEH ++ GIE GD +P
Sbjct: 196 AIEATVHAPVLEGVYSEIYKVLKPGGVFGVYEWVMTDKYDENNEEHRKIAYGIEVGDGIP 255
Query: 816 GLRAYSDIAETAKKVGFEVVKEKDLAAPPAE-PWW 917
+ + K VGF++ EKDLA E PW+
Sbjct: 256 KMYKREVAEQALKNVGFDIEYEKDLADVNDEIPWY 290
>sp|Q96WX4|ERG6_PNECA Sterol 24-C-methyltransferase OS=Pneumocystis carinii
GN=erg6 PE=2 SV=1
Length = 377
Score = 210 bits (532), Expect = 4e-053
Identities = 101/241 (41%), Positives = 153/241 (63%), Gaps = 3/241 (1%)
Frame = +3
Query: 276 FYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGG 455
+YNLVTD YE+GW SFHF + +S A HE ++ G+ +LDVGCGVGG
Sbjct: 80 YYNLVTDFYEYGWSTSFHFCRFAKDESFSQAIARHEHYIALHAGIREGETVLDVGCGVGG 139
Query: 456 PMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAY 635
P I+ + AN+VG+ N+YQ++RA+ ++ K GL + + G+F+QMPF +N+FD Y
Sbjct: 140 PACQISVFTGANIVGLNNNDYQIQRAKYYSEKKGLSDKLKFIKGDFMQMPFPENSFDKIY 199
Query: 636 SIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALP 815
SIEAT HAP LE VY+EIYRVLKPG LY SYEWV +K++ + EH +++ GIE GD++P
Sbjct: 200 SIEATIHAPSLEGVYSEIYRVLKPGGLYASYEWVMLNKYDENDPEHQQIVYGIEIGDSIP 259
Query: 816 GLRAYSDIAETAKKVGFEVVKEKDLAAPPAE-PWWTRL--KMGRLAYWRNHIVVQVLSAV 986
+ + KVGFE++ ++L+ + PW+ L + ++ +R+ I + ++ +
Sbjct: 260 KISKIGEAEAALIKVGFEIIHSEELSTKNSPLPWYYYLDGDLRKVRSFRDFISIARMTTI 319
Query: 987 G 989
G
Sbjct: 320 G 320
>sp|P25087|ERG6_YEAST Sterol 24-C-methyltransferase OS=Saccharomyces cerevisiae
GN=ERG6 PE=1 SV=4
Length = 383
Score = 210 bits (532), Expect = 4e-053
Identities = 114/275 (41%), Positives = 160/275 (58%), Gaps = 4/275 (1%)
Frame = +3
Query: 138 GKRALDLSGGSISAEKVEDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEWGWG 317
G AL S E V+ + + + E E + ++YN+VTD YE+GWG
Sbjct: 27 GLSALMSKNNSAQKEAVQKYLRNWDGRTDKDAEERRLEDYNEATHSYYNVVTDFYEYGWG 86
Query: 318 QSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVV 497
SFHFS +G+S + HE ++ G +LDVGCGVGGP R IA + NV+
Sbjct: 87 SSFHFSRFYKGESFAASIARHEHYLAYKAGIQRGDLVLDVGCGVGGPAREIARFTGCNVI 146
Query: 498 GITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEV 677
G+ N+YQ+ +A+ + +K L + V G+F++M F++NTFD Y+IEATCHAPKLE V
Sbjct: 147 GLNNNDYQIAKAKYYAKKYNLSDQMDFVKGDFMKMDFEENTFDKVYAIEATCHAPKLEGV 206
Query: 678 YAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAETA-K 854
Y+EIY+VLKPG + YEWV TDK++ N EH ++ IE GD +P + + D+A A K
Sbjct: 207 YSEIYKVLKPGGTFAVYEWVMTDKYDENNPEHRKIAYEIELGDGIPKM-FHVDVARKALK 265
Query: 855 KVGFEVVKEKDLAAPPAE-PWWTRLKMGRLAYWRN 956
GFEV+ +DLA E PW+ L G Y +N
Sbjct: 266 NCGFEVLVSEDLADNDDEIPWYYPL-TGEWKYVQN 299
>sp|Q5EN22|ERG6_MAGGR Sterol 24-C-methyltransferase OS=Magnaporthe grisea
GN=ERG6 PE=2 SV=2
Length = 390
Score = 208 bits (528), Expect = 1e-052
Identities = 117/289 (40%), Positives = 160/289 (55%), Gaps = 14/289 (4%)
Frame = +3
Query: 192 DNYKQYWSFFRRPKEIETA----EKVPDFVD---TFYNLVTDIYEWGWGQSFHFSPSIRG 350
D Y ++W + + ET E+ D+ +YNLVTD YE+GWGQSFHF G
Sbjct: 55 DQYFRHWD--GKTAKTETTKVREERKADYATLTRQYYNLVTDFYEYGWGQSFHFCTFAPG 112
Query: 351 KSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKR 530
++ A +E I +K G K+LD+GCGVGGP R IA + AN+ GITINEYQV+R
Sbjct: 113 ETFASAITRYEHTLAHRIGIKKGMKVLDIGCGVGGPARQIAKFTGANITGITINEYQVER 172
Query: 531 ARDHNRKAGLDA--LCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLK 704
AR + G A + V G+F+ +PF+ TFD YSIEAT HAPKLE+VY +I+ VLK
Sbjct: 173 ARRYAEMEGYGAGEQLKFVQGDFMALPFEKETFDAVYSIEATVHAPKLEDVYKQIFNVLK 232
Query: 705 PGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALPGLRAYSDIAETAKKVGFEVVKEK 884
PG ++ YEWV TD ++ + H E+ GIE G + L+ K GFE+++ +
Sbjct: 233 PGGIFGLYEWVMTDAYDENDPHHKEIRFGIEHGGGIANLQTAQTAIAAIKAAGFELLESE 292
Query: 885 DLA-APPAEPWWTRLKMGRLAYWRNHIVVQVLSAVGVAPKGTVDVHEML 1028
DLA PW+ L G A+ +LS + P G H +L
Sbjct: 293 DLADNSDRAPWYWPL--GGNAWQYASTFGDILSTFTMTPAGRAIAHTVL 339
>sp|Q9P3R1|ERG6_NEUCR Sterol 24-C-methyltransferase OS=Neurospora crassa
GN=B24P7.240 PE=3 SV=1
Length = 379
Score = 202 bits (512), Expect = 8e-051
Identities = 103/230 (44%), Positives = 140/230 (60%), Gaps = 2/230 (0%)
Frame = +3
Query: 276 FYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVGG 455
+YNL TDIYE+GWGQ FHF G+S A HE I +K K+LDVGCGVGG
Sbjct: 82 YYNLATDIYEYGWGQCFHFCRYSPGESFYQAIARHEHYLAAQIGIKKDMKVLDVGCGVGG 141
Query: 456 PMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAY 635
P R IA + A++ G+ N+YQ+ RA + + GL + V G+F+QM F DN+FD Y
Sbjct: 142 PAREIAKFTDAHITGLNNNDYQIDRATHYAVRDGLSGQLKFVKGDFMQMSFPDNSFDAVY 201
Query: 636 SIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDALP 815
+IEAT HAPKLE VY EIYRVLKPG + YEW+ TD ++ +N EH ++ IE G+ +
Sbjct: 202 AIEATVHAPKLEGVYGEIYRVLKPGGTFGVYEWLMTDNYDNDNVEHRDIRLAIEVGNGIS 261
Query: 816 GLRAYSDIAETAKKVGFEVVKEKDLA-APPAEPWWTRLKMGRLAYWRNHI 962
+ S+ K VGFE+V +DLA PW+ + G L Y ++++
Sbjct: 262 NMVTISEGLAAMKNVGFELVHHEDLADRNDPMPWYWPI-AGELRYMQSYL 310
>sp|Q759S7|ERG6_ASHGO Sterol 24-C-methyltransferase OS=Ashbya gossypii GN=ERG6
PE=3 SV=1
Length = 373
Score = 197 bits (500), Expect = 2e-049
Identities = 99/226 (43%), Positives = 133/226 (58%), Gaps = 2/226 (0%)
Frame = +3
Query: 273 TFYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKPGQKILDVGCGVG 452
++YN+VTD YE+GWG SFHFS G+S + HE + G +LDVGCGVG
Sbjct: 73 SYYNVVTDFYEYGWGASFHFSRFYTGESFAMSMARHEHYLAHRAGITSGDLVLDVGCGVG 132
Query: 453 GPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGA 632
GP R IA + VVG+ N+YQ+ + + ++RK GL V G+F+ M F D TFD
Sbjct: 133 GPAREIARFTGCRVVGLNNNDYQIMKGKHYSRKLGLGDQVSYVKGDFMNMDFPDATFDKV 192
Query: 633 YSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFNAENEEHVEVIQGIERGDAL 812
Y+IEATCHAP E VY EIYRVLKPG ++ YEWV T+ ++ N EH + IE GD +
Sbjct: 193 YAIEATCHAPSFEGVYGEIYRVLKPGGVFAVYEWVMTENYDETNPEHRRIAYDIELGDGI 252
Query: 813 PGLRAYSDIAETAKKVGFEVVKEKDLA-APPAEPWWTRLKMGRLAY 947
P + + + KVGFE++ ++D A PW+ L G AY
Sbjct: 253 PKMYSVKVARDALAKVGFEILVDEDRADNDDPVPWYYPL-TGEWAY 297
>sp|Q9ZSK1|GTOMC_ARATH Tocopherol O-methyltransferase, chloroplastic
OS=Arabidopsis thaliana GN=G-TMT PE=2 SV=2
Length = 348
Score = 72 bits (176), Expect = 7e-012
Identities = 45/140 (32%), Positives = 66/140 (47%), Gaps = 6/140 (4%)
Frame = +3
Query: 333 SPSIRGKSHRDA-TRLHEEM-----AVDLIQVKPGQKILDVGCGVGGPMRAIASHSRANV 494
S + H++A R+ EE D + K +K++DVGCG+GG R +AS A
Sbjct: 93 SVQLSDSGHKEAQIRMIEESLRFAGVTDEEEEKKIKKVVDVGCGIGGSSRYLASKFGAEC 152
Query: 495 VGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEE 674
+GIT++ Q KRA D L + L PF+D FD +S+E+ H P +
Sbjct: 153 IGITLSPVQAKRANDLAAAQSLAHKASFQVADALDQPFEDGKFDLVWSMESGEHMPDKAK 212
Query: 675 VYAEIYRVLKPGSLYVSYEW 734
E+ RV PG + W
Sbjct: 213 FVKELVRVAAPGGRIIIVTW 232
>sp|Q9C6B9|PEAM3_ARATH Putative phosphoethanolamine N-methyltransferase 3
OS=Arabidopsis thaliana GN=NMT3 PE=2 SV=2
Length = 490
Score = 72 bits (174), Expect = 1e-011
Identities = 39/119 (32%), Positives = 62/119 (52%), Gaps = 2/119 (1%)
Frame = +3
Query: 393 VDLIQVKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALC 572
VD++ +KPGQK+LDVGCG+GG +A + +VVGI ++ + A +H GL
Sbjct: 274 VDMLDLKPGQKVLDVGCGIGGGDFYMAENFDVDVVGIDLSVNMISFALEH--AIGLKCSV 331
Query: 573 EVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDK 749
E + + + DNTFD YS + H ++ Y+ LKPG + ++ + K
Sbjct: 332 EFEVADCTKKEYPDNTFDVIYSRDTILHIQDKPALFRRFYKWLKPGGKVLITDYCRSPK 390
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 99,823,088,839
Number of Sequences: 518415
Number of Extensions: 99823088839
Number of Successful Extensions: 648260893
Number of sequences better than 0.0: 0
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