BLASTX 7.6.2
Query= UN24223 /QuerySize=940
(939 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8GY23|UPL1_ARATH E3 ubiquitin-protein ligase UPL1 OS=Arabido... 448 4e-125
sp|Q8H0T4|UPL2_ARATH E3 ubiquitin-protein ligase UPL2 OS=Arabido... 446 1e-124
sp|Q9P4Z1|TOM1_NEUCR E3 ubiquitin-protein ligase TOM1-like OS=Ne... 310 8e-084
sp|O13834|PTR1_SCHPO E3 ubiquitin-protein ligase ptr1 OS=Schizos... 305 5e-082
sp|Q7Z6Z7|HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE1 OS=Homo ... 288 6e-077
sp|Q7TMY8|HUWE1_MOUSE E3 ubiquitin-protein ligase HUWE1 OS=Mus m... 288 6e-077
sp|P51593|HUWE1_RAT E3 ubiquitin-protein ligase HUWE1 (Fragment)... 288 6e-077
sp|Q756G2|TOM1_ASHGO Probable E3 ubiquitin-protein ligase TOM1 O... 282 4e-075
sp|Q03280|TOM1_YEAST E3 ubiquitin-protein ligase TOM1 OS=Sacchar... 273 1e-072
sp|O14326|PUB3_SCHPO E3 ubiquitin-protein ligase pub3 OS=Schizos... 265 5e-070
sp|Q92462|PUB1_SCHPO E3 ubiquitin-protein ligase pub1 OS=Schizos... 256 2e-067
sp|P39940|RSP5_YEAST E3 ubiquitin-protein ligase RSP5 OS=Sacchar... 238 4e-062
sp|Q5BDP1|RSP5_EMENI E3 ubiquitin-protein ligase RSP5 OS=Emerice... 237 9e-062
sp|A1D3C5|RSP5_NEOFI Probable E3 ubiquitin-protein ligase hulA O... 235 3e-061
sp|A2A5Z6|SMUF2_MOUSE E3 ubiquitin-protein ligase SMURF2 OS=Mus ... 235 3e-061
sp|B0XQ72|RSP5_ASPFC Probable E3 ubiquitin-protein ligase hulA O... 235 4e-061
sp|Q4WTF3|RSP5_ASPFU Probable E3 ubiquitin-protein ligase hulA O... 235 4e-061
sp|Q0CCL1|RSP5_ASPTN Probable E3 ubiquitin-protein ligase hulA O... 235 4e-061
sp|A2QQ28|RSP5_ASPNC Probable E3 ubiquitin-protein ligase hulA O... 234 1e-060
sp|Q9HAU4|SMUF2_HUMAN E3 ubiquitin-protein ligase SMURF2 OS=Homo... 233 1e-060
>sp|Q8GY23|UPL1_ARATH E3 ubiquitin-protein ligase UPL1 OS=Arabidopsis thaliana
GN=UPL1 PE=1 SV=3
Length = 3681
Score = 448 bits (1150), Expect = 4e-125
Identities = 216/261 (82%), Positives = 237/261 (90%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDAD 760
FDGQLLDV+FTRSFYKHILGVKVTYHDIEA+DPDYYK LKW+LEND+SD+LDLTFS+DAD
Sbjct: 3420 FDGQLLDVYFTRSFYKHILGVKVTYHDIEAVDPDYYKNLKWLLENDVSDILDLTFSMDAD 3479
Query: 759 EEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSE 580
EEK ILYEKTEVTD+EL PGGRNI+VTEE KHEYVDL+A H LT AIRPQINAFLEGF+E
Sbjct: 3480 EEKHILYEKTEVTDYELKPGGRNIRVTEETKHEYVDLVAGHILTNAIRPQINAFLEGFNE 3539
Query: 579 LILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKED 400
LI ++L+SIFNDKELELLISGLP+ID D+L+ANTEY+ Y+ GSPVI WFWEVV+ SKED
Sbjct: 3540 LIPRELVSIFNDKELELLISGLPEIDFDDLKANTEYTSYTAGSPVIHWFWEVVKAFSKED 3599
Query: 399 KARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPS 220
AR LQFVTGTSKVPLEGF ALQGISG Q+ QIHKAYG+ LPSAHTCFNQLDLPEY S
Sbjct: 3600 MARFLQFVTGTSKVPLEGFKALQGISGPQRLQIHKAYGAPERLPSAHTCFNQLDLPEYQS 3659
Query: 219 KEHLQERLLLAIHEASEGFGF 157
KE LQERLLLAIHEASEGFGF
Sbjct: 3660 KEQLQERLLLAIHEASEGFGF 3680
>sp|Q8H0T4|UPL2_ARATH E3 ubiquitin-protein ligase UPL2 OS=Arabidopsis thaliana
GN=UPL2 PE=1 SV=2
Length = 3658
Score = 446 bits (1146), Expect = 1e-124
Identities = 214/261 (81%), Positives = 239/261 (91%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDAD 760
FDGQLLDV+FTRSFYKHILGVKVTYHDIEA+DPDYYK LKW+LEND+SD+LDLTFS+DAD
Sbjct: 3397 FDGQLLDVYFTRSFYKHILGVKVTYHDIEAVDPDYYKNLKWLLENDVSDILDLTFSMDAD 3456
Query: 759 EEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSE 580
EEK ILYEKTEVTD+EL PGGRNI+VTEE KHEYVDL+A+H LT+AIRPQINAFLEG +E
Sbjct: 3457 EEKHILYEKTEVTDYELKPGGRNIRVTEETKHEYVDLVADHILTSAIRPQINAFLEGLNE 3516
Query: 579 LILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKED 400
LI ++L+SIFNDKELELLISGLP+ID D+L+ANTEY+ Y+ GSPVI+WFWEVV+ SKED
Sbjct: 3517 LIPRELVSIFNDKELELLISGLPEIDFDDLKANTEYTSYTVGSPVIRWFWEVVKAFSKED 3576
Query: 399 KARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPS 220
AR LQFVTGTSKVPLEGF ALQGISG Q+ QIHKAYGS LPSAHTCFNQLDLPEY S
Sbjct: 3577 MARFLQFVTGTSKVPLEGFKALQGISGPQRLQIHKAYGSPERLPSAHTCFNQLDLPEYQS 3636
Query: 219 KEHLQERLLLAIHEASEGFGF 157
KE +QERLLLAIHEA+EGFGF
Sbjct: 3637 KEQVQERLLLAIHEANEGFGF 3657
>sp|Q9P4Z1|TOM1_NEUCR E3 ubiquitin-protein ligase TOM1-like OS=Neurospora crassa
GN=B11B22.010 PE=3 SV=3
Length = 4026
Score = 310 bits (794), Expect = 8e-084
Identities = 151/261 (57%), Positives = 199/261 (76%), Gaps = 7/261 (2%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDAD 760
++G+LL+ +F+R+ YK ILG V+ D+E+ DPDYYK+L WMLENDI+D++ TFSV+ D
Sbjct: 3772 YEGRLLECYFSRAVYKRILGKPVSVKDMESFDPDYYKSLVWMLENDITDIITETFSVEDD 3831
Query: 759 EEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSE 580
++ + +V D LI GRNI VTEENKHEYV LI EH+L T+++ Q+ AFL GF E
Sbjct: 3832 -----VFGEVKVVD--LIENGRNIPVTEENKHEYVRLIVEHKLITSVKDQMKAFLTGFHE 3884
Query: 579 LILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKED 400
+I ++LI+IFN++ELELLISGLPDID+D+ +ANTEY YS G+P IQWFW V+ KE+
Sbjct: 3885 IIPEELIAIFNEQELELLISGLPDIDIDDWKANTEYHNYSAGAPQIQWFWRAVRSFDKEE 3944
Query: 399 KARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPS 220
A+LLQFVTGTSKVPL GF L+G++G +F IH+ YGS + LPS+HTCFNQLDLPEY +
Sbjct: 3945 LAKLLQFVTGTSKVPLNGFKELEGMNGVSRFNIHRDYGSKDRLPSSHTCFNQLDLPEYEN 4004
Query: 219 KEHLQERLLLAIHEASEGFGF 157
E L+ +LL AI S+ FGF
Sbjct: 4005 YETLRSQLLKAITAGSDYFGF 4025
>sp|O13834|PTR1_SCHPO E3 ubiquitin-protein ligase ptr1 OS=Schizosaccharomyces
pombe GN=ptr1 PE=1 SV=1
Length = 3227
Score = 305 bits (779), Expect = 5e-082
Identities = 145/261 (55%), Positives = 195/261 (74%), Gaps = 7/261 (2%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDAD 760
+DG+LLD HF+R+ YKH+L V+ DIE++DPDYYK+L WML NDI+D++ F+V+ D
Sbjct: 2973 YDGRLLDCHFSRAVYKHMLHRSVSVKDIESLDPDYYKSLVWMLNNDITDIITEEFAVEKD 3032
Query: 759 EEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSE 580
+ EKT V +LIP GRNI VTE NK YV+ + +++L +++ Q+ + L+GFS+
Sbjct: 3033 ----VFGEKTVV---DLIPNGRNIPVTELNKQNYVNRMVDYKLRESVKDQLKSLLDGFSD 3085
Query: 579 LILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKED 400
+I LI IFN++ELELLISGLP+ID+D+ + NTEY GY+ SP +QWFW V+ +E+
Sbjct: 3086 IIPSHLIQIFNEQELELLISGLPEIDIDDWKNNTEYHGYNVSSPQVQWFWRAVRSFDEEE 3145
Query: 399 KARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPS 220
+A+LLQF TGTSKVPL GF L+G+SG Q+F IHK+YGS N LP +HTCFNQLDLPEY +
Sbjct: 3146 RAKLLQFATGTSKVPLNGFKELEGMSGFQRFNIHKSYGSLNRLPQSHTCFNQLDLPEYDT 3205
Query: 219 KEHLQERLLLAIHEASEGFGF 157
E L+ LL AI+E SEGFGF
Sbjct: 3206 YEQLRSMLLTAINEGSEGFGF 3226
>sp|Q7Z6Z7|HUWE1_HUMAN E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens
GN=HUWE1 PE=1 SV=3
Length = 4374
Score = 288 bits (735), Expect = 6e-077
Identities = 151/261 (57%), Positives = 189/261 (72%), Gaps = 8/261 (3%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDV-LDLTFSVDA 763
+D +LL+ +FTRSFYKHILG V Y D+E+ D +Y+ L ++LEND+S + DLTFS +
Sbjct: 4119 YDNRLLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEV 4178
Query: 762 DEEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFS 583
E + EV D L P G NI VTEENK EYV L+ + R+T AIR Q+ AFLEGF
Sbjct: 4179 QE-----FGVCEVRD--LKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFY 4231
Query: 582 ELILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKE 403
E+I K LISIF ++ELELLISGLP ID+D+L++NTEY Y S IQWFW ++ +
Sbjct: 4232 EIIPKRLISIFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQA 4291
Query: 402 DKARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYP 223
D+A+ LQFVTGTSKVPL+GF+AL+G++G QKFQIH+ S + LPSAHTCFNQLDLP Y
Sbjct: 4292 DRAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYE 4351
Query: 222 SKEHLQERLLLAIHEASEGFG 160
S E L+ LLLAI E SEGFG
Sbjct: 4352 SFEKLRHMLLLAIQECSEGFG 4372
>sp|Q7TMY8|HUWE1_MOUSE E3 ubiquitin-protein ligase HUWE1 OS=Mus musculus
GN=Huwe1 PE=1 SV=4
Length = 4377
Score = 288 bits (735), Expect = 6e-077
Identities = 151/261 (57%), Positives = 189/261 (72%), Gaps = 8/261 (3%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDV-LDLTFSVDA 763
+D +LL+ +FTRSFYKHILG V Y D+E+ D +Y+ L ++LEND+S + DLTFS +
Sbjct: 4122 YDNRLLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEV 4181
Query: 762 DEEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFS 583
E + EV D L P G NI VTEENK EYV L+ + R+T AIR Q+ AFLEGF
Sbjct: 4182 QE-----FGVCEVRD--LKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFY 4234
Query: 582 ELILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKE 403
E+I K LISIF ++ELELLISGLP ID+D+L++NTEY Y S IQWFW ++ +
Sbjct: 4235 EIIPKRLISIFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQA 4294
Query: 402 DKARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYP 223
D+A+ LQFVTGTSKVPL+GF+AL+G++G QKFQIH+ S + LPSAHTCFNQLDLP Y
Sbjct: 4295 DRAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYE 4354
Query: 222 SKEHLQERLLLAIHEASEGFG 160
S E L+ LLLAI E SEGFG
Sbjct: 4355 SFEKLRHMLLLAIQECSEGFG 4375
>sp|P51593|HUWE1_RAT E3 ubiquitin-protein ligase HUWE1 (Fragment) OS=Rattus
norvegicus GN=Huwe1 PE=1 SV=2
Length = 322
Score = 288 bits (735), Expect = 6e-077
Identities = 151/261 (57%), Positives = 189/261 (72%), Gaps = 8/261 (3%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDV-LDLTFSVDA 763
+D +LL+ +FTRSFYKHILG V Y D+E+ D +Y+ L ++LEND+S + DLTFS +
Sbjct: 67 YDNRLLECYFTRSFYKHILGKSVRYTDMESEDYHFYQGLVYLLENDVSTLGYDLTFSTEV 126
Query: 762 DEEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFS 583
E + EV D L P G NI VTEENK EYV L+ + R+T AIR Q+ AFLEGF
Sbjct: 127 QE-----FGVCEVRD--LKPNGANILVTEENKKEYVHLVCQMRMTGAIRKQLAAFLEGFY 179
Query: 582 ELILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKE 403
E+I K LISIF ++ELELLISGLP ID+D+L++NTEY Y S IQWFW ++ +
Sbjct: 180 EIIPKRLISIFTEQELELLISGLPTIDIDDLKSNTEYHKYQSNSIQIQWFWRALRSFDQA 239
Query: 402 DKARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYP 223
D+A+ LQFVTGTSKVPL+GF+AL+G++G QKFQIH+ S + LPSAHTCFNQLDLP Y
Sbjct: 240 DRAKFLQFVTGTSKVPLQGFAALEGMNGIQKFQIHRDDRSTDRLPSAHTCFNQLDLPAYE 299
Query: 222 SKEHLQERLLLAIHEASEGFG 160
S E L+ LLLAI E SEGFG
Sbjct: 300 SFEKLRHMLLLAIQECSEGFG 320
>sp|Q756G2|TOM1_ASHGO Probable E3 ubiquitin-protein ligase TOM1 OS=Ashbya
gossypii GN=TOM1 PE=3 SV=1
Length = 3258
Score = 282 bits (719), Expect = 4e-075
Identities = 140/259 (54%), Positives = 187/259 (72%), Gaps = 7/259 (2%)
Frame = -1
Query: 936 DGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDADE 757
D LD HF+R YK+ILG V D+E++D DYYK+L W+LENDI+D+++ TFSV+ D+
Sbjct: 3005 DQCFLDCHFSREVYKNILGKPVALKDMESLDLDYYKSLIWILENDITDIIEETFSVETDD 3064
Query: 756 EKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSEL 577
Y + +V ELI G ++ VTE+NKH+YV I E++L T+++ Q+ FL+GF +
Sbjct: 3065 -----YGEHKVI--ELIENGAHVAVTEQNKHDYVKKIVEYKLQTSVKDQMENFLQGFYAI 3117
Query: 576 ILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKEDK 397
I KDLISIF+++ELELL+SGLPDID+D+ + NT Y Y+P I +FW V+ KE++
Sbjct: 3118 IPKDLISIFDEQELELLVSGLPDIDVDDWKNNTIYVNYTPTCKQINYFWRAVRSFDKEER 3177
Query: 396 ARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPSK 217
A+LLQFVTGTSKVPL GF L G++G KF IH+ YGS + LPS+HTCFNQLDLP Y S
Sbjct: 3178 AKLLQFVTGTSKVPLNGFKELSGVNGISKFSIHRDYGSIDRLPSSHTCFNQLDLPAYDSY 3237
Query: 216 EHLQERLLLAIHEASEGFG 160
E L+ LLLAI+E EGFG
Sbjct: 3238 ETLRGSLLLAINEGHEGFG 3256
>sp|Q03280|TOM1_YEAST E3 ubiquitin-protein ligase TOM1 OS=Saccharomyces
cerevisiae GN=TOM1 PE=1 SV=1
Length = 3268
Score = 273 bits (697), Expect = 1e-072
Identities = 136/259 (52%), Positives = 187/259 (72%), Gaps = 7/259 (2%)
Frame = -1
Query: 936 DGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDADE 757
D LD HF+R YK+ILG V+ D+E++DPDYYK+L W+LENDI+D+++ TFSV+ D+
Sbjct: 3015 DQCFLDCHFSREVYKNILGRPVSLKDMESLDPDYYKSLVWILENDITDIIEETFSVETDD 3074
Query: 756 EKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSEL 577
Y + +V + LI GG++I VTE NK +YV + E++L T+++ Q++ FL GF L
Sbjct: 3075 -----YGEHKVIN--LIEGGKDIIVTEANKQDYVKKVVEYKLQTSVKEQMDNFLVGFYAL 3127
Query: 576 ILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKEDK 397
I KDLI+IF+++ELELLISGLPDID+D+ + NT Y Y+ + +FW V+ E++
Sbjct: 3128 ISKDLITIFDEQELELLISGLPDIDVDDWKNNTTYVNYTATCKEVSYFWRAVRSFDAEER 3187
Query: 396 ARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPSK 217
A+LLQFVTGTSKVPL GF L G++G KF IH+ +GS+ LPS+HTCFNQL+LP Y S
Sbjct: 3188 AKLLQFVTGTSKVPLNGFKELSGVNGVCKFSIHRDFGSSERLPSSHTCFNQLNLPPYESY 3247
Query: 216 EHLQERLLLAIHEASEGFG 160
E L+ LLLAI+E EGFG
Sbjct: 3248 ETLRGSLLLAINEGHEGFG 3266
>sp|O14326|PUB3_SCHPO E3 ubiquitin-protein ligase pub3 OS=Schizosaccharomyces
pombe GN=pub3 PE=2 SV=1
Length = 786
Score = 265 bits (675), Expect = 5e-070
Identities = 131/260 (50%), Positives = 183/260 (70%), Gaps = 9/260 (3%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDAD 760
F + LD F S YK +L KV+ D+E+ID ++Y++LKW+LENDI+ +LDLTFSV+ D
Sbjct: 534 FHRRFLDAFFVVSLYKKLLRKKVSLADMESIDAEFYRSLKWVLENDITGILDLTFSVEED 593
Query: 759 EEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSE 580
EV ELI G NI+VTEENK +YVDL+ E R++ + Q NAF GF E
Sbjct: 594 -------HFGEVRTVELITNGENIEVTEENKKKYVDLVTEWRVSKRVEQQFNAFYSGFVE 646
Query: 579 LILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKED 400
L+ DL+++F+++ELELLI G+ D+D+++ +++TEY Y PVI+WFWE++ G ED
Sbjct: 647 LVSPDLVNVFDERELELLIGGISDVDVEDWKSHTEYRTYIATDPVIKWFWEIIAGWKNED 706
Query: 399 KARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPS 220
+++LLQF TGTS++P+ GF LQG G +KF I KA G+ + LP AHTCFN+LDLP+YPS
Sbjct: 707 RSKLLQFATGTSRIPVNGFRDLQGSDGPRKFTIEKA-GTPDQLPVAHTCFNRLDLPDYPS 765
Query: 219 KEHLQERLLLAIHEASEGFG 160
K+ L E+L LA+ E + GFG
Sbjct: 766 KDTLHEKLSLAV-ENTVGFG 784
>sp|Q92462|PUB1_SCHPO E3 ubiquitin-protein ligase pub1 OS=Schizosaccharomyces
pombe GN=pub1 PE=1 SV=2
Length = 767
Score = 256 bits (653), Expect = 2e-067
Identities = 133/260 (51%), Positives = 179/260 (68%), Gaps = 9/260 (3%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDAD 760
F + +D F SFYK IL KVT D+E++D +YY++L W+L+NDI+ VLDLTFSV
Sbjct: 515 FHRRFVDAFFVVSFYKMILQKKVTLQDMESMDAEYYRSLVWILDNDITGVLDLTFSV--- 571
Query: 759 EEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSE 580
E+ EV +L P GRNI+VTEENK EYVDL+ R+ I Q NAF EGFSE
Sbjct: 572 EDNCF----GEVVTIDLKPNGRNIEVTEENKREYVDLVTVWRIQKRIEEQFNAFHEGFSE 627
Query: 579 LILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKED 400
LI ++LI++F+++ELELLI G+ +ID+++ + +T+Y YS +I+WFWE++ S E
Sbjct: 628 LIPQELINVFDERELELLIGGISEIDMEDWKKHTDYRSYSENDQIIKWFWELMDEWSNEK 687
Query: 399 KARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPS 220
K+RLLQF TGTS++P+ GF LQG G +KF I KA G N LP AHTCFN+LDLP Y S
Sbjct: 688 KSRLLQFTTGTSRIPVNGFKDLQGSDGPRKFTIEKA-GEPNKLPKAHTCFNRLDLPPYTS 746
Query: 219 KEHLQERLLLAIHEASEGFG 160
K+ L +L +A+ E + GFG
Sbjct: 747 KKDLDHKLSIAVEE-TIGFG 765
>sp|P39940|RSP5_YEAST E3 ubiquitin-protein ligase RSP5 OS=Saccharomyces
cerevisiae GN=RSP5 PE=1 SV=1
Length = 809
Score = 238 bits (607), Expect = 4e-062
Identities = 119/260 (45%), Positives = 172/260 (66%), Gaps = 9/260 (3%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDAD 760
F + LD F + YK +L KV D+E +D + Y +L WMLEN I VLDLTFS AD
Sbjct: 557 FHRRFLDAFFVGALYKMMLRKKVVLQDMEGVDAEVYNSLNWMLENSIDGVLDLTFS--AD 614
Query: 759 EEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSE 580
+E+ EV +L P GRNI+VT+ NK EYV+L + R+ ++ Q AF++GF+E
Sbjct: 615 DERF-----GEVVTVDLKPDGRNIEVTDGNKKEYVELYTQWRIVDRVQEQFKAFMDGFNE 669
Query: 579 LILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKED 400
LI +DL+++F+++ELELLI G+ +ID+++ + +T+Y GY VIQWFW+ V E
Sbjct: 670 LIPEDLVTVFDERELELLIGGIAEIDIEDWKKHTDYRGYQESDEVIQWFWKCVSEWDNEQ 729
Query: 399 KARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPS 220
+ARLLQF TGTS++P+ GF LQG G ++F I KA G LP +HTCFN++DLP+Y
Sbjct: 730 RARLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKA-GEVQQLPKSHTCFNRVDLPQYVD 788
Query: 219 KEHLQERLLLAIHEASEGFG 160
+ ++++L LA+ E + GFG
Sbjct: 789 YDSMKQKLTLAVEE-TIGFG 807
>sp|Q5BDP1|RSP5_EMENI E3 ubiquitin-protein ligase RSP5 OS=Emericella nidulans
GN=hulA PE=1 SV=1
Length = 821
Score = 237 bits (604), Expect = 9e-062
Identities = 123/260 (47%), Positives = 172/260 (66%), Gaps = 9/260 (3%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDAD 760
F + LD F +FYK +L KV+ D+E +D D ++ L W LENDI ++DLTF+V D
Sbjct: 569 FHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLTWTLENDIEGIIDLTFTV--D 626
Query: 759 EEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSE 580
+EK E EL PGG +I VT ENKHEYV+L+ E ++ + Q NAF+ GF+E
Sbjct: 627 DEKF-----GERRTIELKPGGEDIPVTNENKHEYVELVTEWKIVKRVEEQFNAFMSGFNE 681
Query: 579 LILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKED 400
LI DL+++F+++ELELLI G+ DID+D+ + +T+Y GY VIQ FW++V+ E
Sbjct: 682 LIPADLVNVFDERELELLIGGIADIDVDDWKKHTDYRGYQEQDEVIQNFWKIVRTWDAEQ 741
Query: 399 KARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPS 220
K+RLLQF TGTS++P+ GF LQG G ++F I K+ G LP +HTCFN+LDLP Y S
Sbjct: 742 KSRLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKS-GDPIALPKSHTCFNRLDLPPYKS 800
Query: 219 KEHLQERLLLAIHEASEGFG 160
E L+ +L +A+ E + GFG
Sbjct: 801 HEVLEHKLSIAVEE-TLGFG 819
>sp|A1D3C5|RSP5_NEOFI Probable E3 ubiquitin-protein ligase hulA OS=Neosartorya
fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181) GN=hulA
PE=3 SV=1
Length = 816
Score = 235 bits (599), Expect = 3e-061
Identities = 123/260 (47%), Positives = 172/260 (66%), Gaps = 9/260 (3%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDAD 760
F + LD F +FYK +L KV+ D+E +D D ++ L W L+NDI VL+LTFSV D
Sbjct: 564 FHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLTWTLDNDIEGVLELTFSV--D 621
Query: 759 EEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSE 580
+EK E +L PGGR+I VT ENK EYV+L+ E ++ + Q NAF+ GF+E
Sbjct: 622 DEKF-----GERRTIDLKPGGRDIPVTNENKAEYVELVTEWKIVKRVEEQFNAFMSGFNE 676
Query: 579 LILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKED 400
LI DL+++F+++ELELLI G+ DID+D+ + +T+Y GY VIQ FW+VV+ E
Sbjct: 677 LIPADLVNVFDERELELLIGGIADIDVDDWKKHTDYRGYQESDEVIQNFWKVVRSWDAEQ 736
Query: 399 KARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPS 220
K+RLLQF TGTS++P+ GF LQG G ++F I K+ G LP +HTCFN+LDLP Y S
Sbjct: 737 KSRLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKS-GDPAALPKSHTCFNRLDLPPYKS 795
Query: 219 KEHLQERLLLAIHEASEGFG 160
E L+ ++ +A+ E + GFG
Sbjct: 796 YETLEHKMSIAVEE-TLGFG 814
>sp|A2A5Z6|SMUF2_MOUSE E3 ubiquitin-protein ligase SMURF2 OS=Mus musculus
GN=Smurf2 PE=2 SV=1
Length = 748
Score = 235 bits (599), Expect = 3e-061
Identities = 120/254 (47%), Positives = 163/254 (64%), Gaps = 7/254 (2%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDAD 760
F G +D FT FYK +LG +T D+E +DPD + +L W+LENDI+ VLD TF V+ +
Sbjct: 495 FHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILENDITGVLDHTFCVEHN 554
Query: 759 EEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSE 580
E+ HEL P G++I VTEENK EYV L R I Q A +GF+E
Sbjct: 555 -------AYGEIIQHELKPNGKSIPVTEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNE 607
Query: 579 LILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKED 400
+I + L+ F++KELEL+I GL ID+ + + NT +P S V++WFW+ V+ +E
Sbjct: 608 VIPQHLLKTFDEKELELIICGLGKIDVSDWKVNTRLKHCTPDSNVVKWFWKAVEFFDEER 667
Query: 399 KARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPS 220
+ARLLQFVTG+S+VPL+GF ALQG +G + F IH+ N+LP AHTCFN++D+P Y S
Sbjct: 668 RARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRIDIPPYES 727
Query: 219 KEHLQERLLLAIHE 178
E L E+LL AI E
Sbjct: 728 YEKLYEKLLTAIEE 741
>sp|B0XQ72|RSP5_ASPFC Probable E3 ubiquitin-protein ligase hulA OS=Aspergillus
fumigatus (strain CEA10 / CBS 144.89 / FGSC A1163) GN=hulA PE=3 SV=2
Length = 813
Score = 235 bits (598), Expect = 4e-061
Identities = 122/260 (46%), Positives = 172/260 (66%), Gaps = 9/260 (3%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDAD 760
F + LD F +FYK +L KV+ D+E +D D ++ L W L+NDI VL+LTFSV D
Sbjct: 561 FHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLTWTLDNDIEGVLELTFSV--D 618
Query: 759 EEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSE 580
+EK E +L PGGR+I VT ENK EYV+L+ E ++ + Q NAF+ GF+E
Sbjct: 619 DEKF-----GERRTIDLKPGGRDIPVTNENKAEYVELVTEWKIVKRVEEQFNAFMSGFNE 673
Query: 579 LILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKED 400
LI DL+++F+++ELELLI G+ DID+D+ + +T+Y GY VIQ FW++V+ E
Sbjct: 674 LIPADLVNVFDERELELLIGGIADIDVDDWKKHTDYRGYQESDEVIQNFWKIVRSWDAEQ 733
Query: 399 KARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPS 220
K+RLLQF TGTS++P+ GF LQG G ++F I K+ G LP +HTCFN+LDLP Y S
Sbjct: 734 KSRLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKS-GDPAALPKSHTCFNRLDLPPYKS 792
Query: 219 KEHLQERLLLAIHEASEGFG 160
E L+ ++ +A+ E + GFG
Sbjct: 793 YETLEHKMSIAVEE-TLGFG 811
>sp|Q4WTF3|RSP5_ASPFU Probable E3 ubiquitin-protein ligase hulA OS=Aspergillus
fumigatus GN=hulA PE=3 SV=2
Length = 813
Score = 235 bits (598), Expect = 4e-061
Identities = 122/260 (46%), Positives = 172/260 (66%), Gaps = 9/260 (3%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDAD 760
F + LD F +FYK +L KV+ D+E +D D ++ L W L+NDI VL+LTFSV D
Sbjct: 561 FHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLTWTLDNDIEGVLELTFSV--D 618
Query: 759 EEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSE 580
+EK E +L PGGR+I VT ENK EYV+L+ E ++ + Q NAF+ GF+E
Sbjct: 619 DEKF-----GERRTIDLKPGGRDIPVTNENKAEYVELVTEWKIVKRVEEQFNAFMSGFNE 673
Query: 579 LILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKED 400
LI DL+++F+++ELELLI G+ DID+D+ + +T+Y GY VIQ FW++V+ E
Sbjct: 674 LIPADLVNVFDERELELLIGGIADIDVDDWKKHTDYRGYQESDEVIQNFWKIVRSWDAEQ 733
Query: 399 KARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPS 220
K+RLLQF TGTS++P+ GF LQG G ++F I K+ G LP +HTCFN+LDLP Y S
Sbjct: 734 KSRLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKS-GDPAALPKSHTCFNRLDLPPYKS 792
Query: 219 KEHLQERLLLAIHEASEGFG 160
E L+ ++ +A+ E + GFG
Sbjct: 793 YETLEHKMSIAVEE-TLGFG 811
>sp|Q0CCL1|RSP5_ASPTN Probable E3 ubiquitin-protein ligase hulA OS=Aspergillus
terreus (strain NIH 2624 / FGSC A1156) GN=hulA PE=3 SV=1
Length = 808
Score = 235 bits (598), Expect = 4e-061
Identities = 120/260 (46%), Positives = 173/260 (66%), Gaps = 9/260 (3%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDAD 760
F + LD F +FYK +L KV+ D+E +D D ++ L W L+NDI +++LTF+V D
Sbjct: 556 FHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLTWTLDNDIEGIIELTFAV--D 613
Query: 759 EEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSE 580
+EK E +L PGGR+I VT ENKHEYV+L+ E ++ + Q NAF+ GF+E
Sbjct: 614 DEKF-----GERRTIDLKPGGRDIPVTNENKHEYVELVTEWKIVKRVEEQFNAFMSGFNE 668
Query: 579 LILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKED 400
LI DL+++F+++ELELLI G+ DID+D+ + +T+Y GY VIQ FW++V+ E
Sbjct: 669 LIPADLVNVFDERELELLIGGIADIDVDDWKKHTDYRGYQEQDEVIQNFWKIVRTWDAEQ 728
Query: 399 KARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPS 220
K+RLLQF TGTS++P+ GF LQG G ++F I K+ G LP +HTCFN+LDLP Y +
Sbjct: 729 KSRLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKS-GDPAALPKSHTCFNRLDLPPYKT 787
Query: 219 KEHLQERLLLAIHEASEGFG 160
E L+ +L +A+ E + GFG
Sbjct: 788 HETLEHKLSIAVEE-TLGFG 806
>sp|A2QQ28|RSP5_ASPNC Probable E3 ubiquitin-protein ligase hulA OS=Aspergillus
niger (strain CBS 513.88 / FGSC A1513) GN=hulA PE=3 SV=1
Length = 821
Score = 234 bits (595), Expect = 1e-060
Identities = 121/260 (46%), Positives = 173/260 (66%), Gaps = 9/260 (3%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDAD 760
F + LD F +FYK +L KV+ D+E +D D ++ L W LENDI +++LTFSV D
Sbjct: 569 FHRRFLDSFFIGAFYKMMLRKKVSLQDMEGVDEDLHRNLAWTLENDIEGIIELTFSV--D 626
Query: 759 EEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSE 580
+EK E T +L PGGR+I VT ENK EYV+L+ E ++ + Q NAF+ GF+E
Sbjct: 627 DEKF-----GERTTIDLKPGGRDIPVTNENKGEYVELVTEWKIVKRVEEQFNAFMSGFNE 681
Query: 579 LILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKED 400
LI DL+++F+++ELELLI G+ DID+D+ + +T+Y GY VIQ FW++V+ E
Sbjct: 682 LIPADLVNVFDERELELLIGGIADIDVDDWKKHTDYRGYQEQDEVIQNFWKIVRTWDAEQ 741
Query: 399 KARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPS 220
K+RLLQF TGTS++P+ GF LQG G ++F I K+ G LP +HTCFN+LDLP Y +
Sbjct: 742 KSRLLQFTTGTSRIPVNGFKDLQGSDGPRRFTIEKS-GDPIALPKSHTCFNRLDLPPYKT 800
Query: 219 KEHLQERLLLAIHEASEGFG 160
+ L+ +L +A+ E + GFG
Sbjct: 801 HDVLEHKLSIAVEE-TLGFG 819
>sp|Q9HAU4|SMUF2_HUMAN E3 ubiquitin-protein ligase SMURF2 OS=Homo sapiens
GN=SMURF2 PE=1 SV=1
Length = 748
Score = 233 bits (594), Expect = 1e-060
Identities = 118/254 (46%), Positives = 163/254 (64%), Gaps = 7/254 (2%)
Frame = -1
Query: 939 FDGQLLDVHFTRSFYKHILGVKVTYHDIEAIDPDYYKALKWMLENDISDVLDLTFSVDAD 760
F G +D FT FYK +LG +T D+E +DPD + +L W+LENDI+ VLD TF V+ +
Sbjct: 495 FHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILENDITGVLDHTFCVEHN 554
Query: 759 EEKLILYEKTEVTDHELIPGGRNIKVTEENKHEYVDLIAEHRLTTAIRPQINAFLEGFSE 580
E+ HEL P G++I V EENK EYV L R I Q A +GF+E
Sbjct: 555 -------AYGEIIQHELKPNGKSIPVNEENKKEYVRLYVNWRFLRGIEAQFLALQKGFNE 607
Query: 579 LILKDLISIFNDKELELLISGLPDIDLDNLRANTEYSGYSPGSPVIQWFWEVVQGLSKED 400
+I + L+ F++KELEL+I GL ID+++ + NT +P S +++WFW+ V+ +E
Sbjct: 608 VIPQHLLKTFDEKELELIICGLGKIDVNDWKVNTRLKHCTPDSNIVKWFWKAVEFFDEER 667
Query: 399 KARLLQFVTGTSKVPLEGFSALQGISGAQKFQIHKAYGSANHLPSAHTCFNQLDLPEYPS 220
+ARLLQFVTG+S+VPL+GF ALQG +G + F IH+ N+LP AHTCFN++D+P Y S
Sbjct: 668 RARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRIDIPPYES 727
Query: 219 KEHLQERLLLAIHE 178
E L E+LL AI E
Sbjct: 728 YEKLYEKLLTAIEE 741
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 99,823,088,839
Number of Sequences: 518415
Number of Extensions: 99823088839
Number of Successful Extensions: 648260893
Number of sequences better than 0.0: 0
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