BLASTX 7.6.2
Query= UN24394 /QuerySize=1040
(1039 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q0WQ57|AUXI2_ARATH Auxilin-related protein 2 OS=Arabidopsis t... 442 3e-123
sp|Q9SU08|AUXI1_ARATH Auxilin-related protein 1 OS=Arabidopsis t... 434 8e-121
sp|O13773|UCP7_SCHPO UBA domain-containing protein 7 OS=Schizosa... 94 2e-018
sp|Q27974|AUXI_BOVIN Putative tyrosine-protein phosphatase auxil... 81 1e-014
sp|O75061|AUXI_HUMAN Putative tyrosine-protein phosphatase auxil... 81 1e-014
sp|Q99KY4|GAK_MOUSE Cyclin-G-associated kinase OS=Mus musculus G... 81 1e-014
sp|Q80TZ3|AUXI_MOUSE Putative tyrosine-protein phosphatase auxil... 80 2e-014
sp|P97874|GAK_RAT Cyclin-G-associated kinase OS=Rattus norvegicu... 80 2e-014
sp|O14976|GAK_HUMAN Cyclin-G-associated kinase OS=Homo sapiens G... 77 1e-013
sp|Q06677|SWA2_YEAST Auxilin-like clathrin uncoating factor SWA2... 67 2e-010
sp|O80608|FB96_ARATH Putative F-box protein At2g02890 OS=Arabido... 53 3e-006
>sp|Q0WQ57|AUXI2_ARATH Auxilin-related protein 2 OS=Arabidopsis thaliana
GN=At4g12770 PE=1 SV=1
Length = 891
Score = 442 bits (1135), Expect = 3e-123
Identities = 221/246 (89%), Positives = 233/246 (94%), Gaps = 2/246 (0%)
Frame = +2
Query: 5 RAAAQAKAKQQEDNNNDLDSFFNSVSRPSSAPRQRTNPPVDPFQDSWNRGGPYESNRASS 184
RAAAQAKAKQQ++NNNDLDSFFNSVSRPSS PRQRTNPP DPFQDSWN+GG +ES+R SS
Sbjct: 648 RAAAQAKAKQQQENNNDLDSFFNSVSRPSSVPRQRTNPP-DPFQDSWNKGGSFESSRPSS 706
Query: 185 RAPSGASENLRKTSSATNIVDDLSSIFGASAATQSGGFQDIEGETEERRRARLERHQRTQ 364
R PSG +ENLRK SSATNIVDDLSSIFGA A+QSGGFQD++GETEERRRARLERHQRTQ
Sbjct: 707 RVPSGPTENLRKASSATNIVDDLSSIFGA-PASQSGGFQDVDGETEERRRARLERHQRTQ 765
Query: 365 ERAAKALAEKNDRDLQVQREQAEKNRIGETLDVEIKRWGAGKEANLRALLSTLQYVLWPE 544
ERAAKALAEKN+RDLQVQREQAEK+RIG TLDVEI+RWGAGKE NLRALLSTLQYVLWPE
Sbjct: 766 ERAAKALAEKNERDLQVQREQAEKDRIGGTLDVEIRRWGAGKEGNLRALLSTLQYVLWPE 825
Query: 545 CGWQPVSLTDLITAASVKKFYRKATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKF 724
CGWQPVSLTDLIT ASVKK YRKATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKF
Sbjct: 826 CGWQPVSLTDLITGASVKKVYRKATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKF 885
Query: 725 NSEELF 742
NSEELF
Sbjct: 886 NSEELF 891
>sp|Q9SU08|AUXI1_ARATH Auxilin-related protein 1 OS=Arabidopsis thaliana
GN=At4g12780 PE=1 SV=2
Length = 904
Score = 434 bits (1114), Expect = 8e-121
Identities = 217/246 (88%), Positives = 231/246 (93%), Gaps = 2/246 (0%)
Frame = +2
Query: 5 RAAAQAKAKQQEDNNNDLDSFFNSVSRPSSAPRQRTNPPVDPFQDSWNRGGPYESNRASS 184
RAAAQAKAKQQ++N NDLDSFF+S+SRP+SAPRQRTN P+DPFQDSWN+GG +ES+R S
Sbjct: 661 RAAAQAKAKQQQENTNDLDSFFSSISRPNSAPRQRTN-PLDPFQDSWNKGGSFESSRESL 719
Query: 185 RAPSGASENLRKTSSATNIVDDLSSIFGASAATQSGGFQDIEGETEERRRARLERHQRTQ 364
R P G ENLRKTSS TNIVDDLSSIFGAS A+QSGGFQD++GETEERRRARLERHQRTQ
Sbjct: 720 RVPPGQPENLRKTSSVTNIVDDLSSIFGAS-ASQSGGFQDVDGETEERRRARLERHQRTQ 778
Query: 365 ERAAKALAEKNDRDLQVQREQAEKNRIGETLDVEIKRWGAGKEANLRALLSTLQYVLWPE 544
ERAAKALAEKN+RDLQVQREQ EK+RIG TLDVEIKRWGAGKE NLRALLSTLQYVLWPE
Sbjct: 779 ERAAKALAEKNERDLQVQREQVEKDRIGVTLDVEIKRWGAGKEGNLRALLSTLQYVLWPE 838
Query: 545 CGWQPVSLTDLITAASVKKFYRKATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKF 724
CGWQPVSLTDLITAASVKK YRKATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKF
Sbjct: 839 CGWQPVSLTDLITAASVKKVYRKATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKF 898
Query: 725 NSEELF 742
NSEELF
Sbjct: 899 NSEELF 904
>sp|O13773|UCP7_SCHPO UBA domain-containing protein 7 OS=Schizosaccharomyces
pombe GN=ucp7 PE=2 SV=1
Length = 697
Score = 94 bits (231), Expect = 2e-018
Identities = 43/101 (42%), Positives = 65/101 (64%), Gaps = 1/101 (0%)
Frame = +2
Query: 431 EKNRIGETLDVEIKRWGAGKEANLRALLSTLQYVLWPECGWQPVSLTDLITAASVKKFYR 610
E++R+ E + + +W GKE+NLRALL++L +LWPEC WQ VSL++L+ VK Y
Sbjct: 595 ERSRLREPVQQIVNKWKEGKESNLRALLASLDTILWPECRWQKVSLSELVLPKKVKIAYM 654
Query: 611 KATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKFNSE 733
KA +HPDK+ Q+ +++ + IAE F +L AW F +
Sbjct: 655 KAVSRVHPDKLPQQ-TSVEHQLIAESAFSILNHAWELFKQQ 694
>sp|Q27974|AUXI_BOVIN Putative tyrosine-protein phosphatase auxilin OS=Bos
taurus GN=DNAJC6 PE=1 SV=1
Length = 910
Score = 81 bits (199), Expect = 1e-014
Identities = 46/109 (42%), Positives = 66/109 (60%), Gaps = 7/109 (6%)
Frame = +2
Query: 410 QVQREQAEKNRIGETLDVEIKRWGAGKEANLRALLSTLQYVLWP-ECGWQPVSLTDLITA 586
++++E+ K E L +I W GKE N+RALLST+ VLW E W+PV + DL+T
Sbjct: 802 EMRKEEMAKEMDPEKL--KILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTP 859
Query: 587 ASVKKFYRKATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKFNSE 733
VKK YRKA L +HPDK G +Q A+ +F L +AW++F ++
Sbjct: 860 EQVKKVYRKAVLVVHPDKA--TGQPYEQ--YAKMIFMELNDAWSEFENQ 904
>sp|O75061|AUXI_HUMAN Putative tyrosine-protein phosphatase auxilin OS=Homo
sapiens GN=DNAJC6 PE=1 SV=3
Length = 913
Score = 81 bits (199), Expect = 1e-014
Identities = 46/109 (42%), Positives = 66/109 (60%), Gaps = 7/109 (6%)
Frame = +2
Query: 410 QVQREQAEKNRIGETLDVEIKRWGAGKEANLRALLSTLQYVLWP-ECGWQPVSLTDLITA 586
++++E+ K E L +I W GKE N+RALLST+ VLW E W+PV + DL+T
Sbjct: 805 EMRKEEMAKEMDPEKL--KILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTP 862
Query: 587 ASVKKFYRKATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKFNSE 733
VKK YRKA L +HPDK G +Q A+ +F L +AW++F ++
Sbjct: 863 EQVKKVYRKAVLVVHPDKA--TGQPYEQ--YAKMIFMELNDAWSEFENQ 907
>sp|Q99KY4|GAK_MOUSE Cyclin-G-associated kinase OS=Mus musculus GN=Gak PE=1
SV=2
Length = 1305
Score = 81 bits (199), Expect = 1e-014
Identities = 46/117 (39%), Positives = 67/117 (57%), Gaps = 5/117 (4%)
Frame = +2
Query: 386 AEKNDRDLQVQREQAEKNRIGETLDVEIKRWGAGKEANLRALLSTLQYVLWP-ECGWQPV 562
++K + + E R + L +++ W GKE N+RALLSTL VLW E W PV
Sbjct: 1187 SDKKGPKTMAEMRKQELARDTDPLKLKLLDWIEGKERNIRALLSTLHTVLWDGESRWTPV 1246
Query: 563 SLTDLITAASVKKFYRKATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKFNSE 733
S+ DL+T VKK YR+A L +HPDK G +Q A+ +F L +AW++F ++
Sbjct: 1247 SMADLVTPEQVKKQYRRAVLVVHPDKA--TGQPYEQ--YAKMIFMELNDAWSEFENQ 1299
>sp|Q80TZ3|AUXI_MOUSE Putative tyrosine-protein phosphatase auxilin OS=Mus
musculus GN=Dnajc6 PE=2 SV=2
Length = 938
Score = 80 bits (196), Expect = 2e-014
Identities = 45/109 (41%), Positives = 66/109 (60%), Gaps = 7/109 (6%)
Frame = +2
Query: 410 QVQREQAEKNRIGETLDVEIKRWGAGKEANLRALLSTLQYVLWP-ECGWQPVSLTDLITA 586
++++E+ K E L +I W GKE N+RALLST+ VLW E W+PV + DL+T
Sbjct: 830 EMRKEEMAKEMDPEKL--KILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTP 887
Query: 587 ASVKKFYRKATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKFNSE 733
VKK YR+A L +HPDK G +Q A+ +F L +AW++F ++
Sbjct: 888 EQVKKVYRRAVLVVHPDKA--TGQPYEQ--YAKMIFMELNDAWSEFENQ 932
>sp|P97874|GAK_RAT Cyclin-G-associated kinase OS=Rattus norvegicus GN=Gak PE=2
SV=1
Length = 1305
Score = 80 bits (196), Expect = 2e-014
Identities = 45/117 (38%), Positives = 66/117 (56%), Gaps = 5/117 (4%)
Frame = +2
Query: 386 AEKNDRDLQVQREQAEKNRIGETLDVEIKRWGAGKEANLRALLSTLQYVLWP-ECGWQPV 562
++K + + E R + +++ W GKE N+RALLSTL VLW E W PV
Sbjct: 1187 SDKKGPKTMAEMRKQELARDTDPFKLKLLDWIEGKERNIRALLSTLHTVLWDGESRWTPV 1246
Query: 563 SLTDLITAASVKKFYRKATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKFNSE 733
S+ DL+T VKK YR+A L +HPDK G +Q A+ +F L +AW++F ++
Sbjct: 1247 SMADLVTPEQVKKQYRRAVLVVHPDKA--TGQPYEQS--AKMIFMELNDAWSEFENQ 1299
>sp|O14976|GAK_HUMAN Cyclin-G-associated kinase OS=Homo sapiens GN=GAK PE=1
SV=2
Length = 1311
Score = 77 bits (189), Expect = 1e-013
Identities = 40/96 (41%), Positives = 57/96 (59%), Gaps = 5/96 (5%)
Frame = +2
Query: 449 ETLDVEIKRWGAGKEANLRALLSTLQYVLWP-ECGWQPVSLTDLITAASVKKFYRKATLC 625
+ L +++ W GKE N+RALLSTL VLW E W PV + DL+ VKK YR+A L
Sbjct: 1214 DPLKLKLLDWIEGKERNIRALLSTLHTVLWDGESRWTPVGMADLVAPEQVKKHYRRAVLA 1273
Query: 626 IHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKFNSE 733
+HPD K A + A+ +F L +AW++F ++
Sbjct: 1274 VHPD----KAAGQPYEQHAKMIFMELNDAWSEFENQ 1305
>sp|Q06677|SWA2_YEAST Auxilin-like clathrin uncoating factor SWA2
OS=Saccharomyces cerevisiae GN=SWA2 PE=1 SV=1
Length = 668
Score = 67 bits (161), Expect = 2e-010
Identities = 38/112 (33%), Positives = 62/112 (55%), Gaps = 6/112 (5%)
Frame = +2
Query: 398 DRDLQVQREQAEKNRIG--ETLDVEIKRWGAGKEANLRALLSTLQYVL-WPECGWQPVSL 568
D ++++ + E ++ + + +I W GK+ ++R LL+ L +L W C W+ VS+
Sbjct: 553 DSTSEIKKRELENAKLALYDKVFEKISSWKDGKDDDIRHLLANLSSLLTW--CNWKDVSM 610
Query: 569 TDLITAASVKKFYRKATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKF 724
DL+ VK Y KA HPDK+ + +L+ K IAE +F L AW+KF
Sbjct: 611 QDLVMPKRVKITYMKAVAKTHPDKIPE-SLSLENKMIAENIFSTLSIAWDKF 661
>sp|O80608|FB96_ARATH Putative F-box protein At2g02890 OS=Arabidopsis thaliana
GN=At2g02890 PE=4 SV=1
Length = 531
Score = 53 bits (126), Expect = 3e-006
Identities = 27/33 (81%), Positives = 28/33 (84%)
Frame = -2
Query: 102 RGALLGLETELKKESRSLLLSSCCLALACAAAL 4
R LLGLETELKK+SRSLL S CCLALA AAAL
Sbjct: 27 RSTLLGLETELKKDSRSLLFSCCCLALAWAAAL 59
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,745,191,639
Number of Sequences: 518415
Number of Extensions: 102745191639
Number of Successful Extensions: 656160410
Number of sequences better than 0.0: 0
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