BLASTX 7.6.2
Query= UN24941 /QuerySize=1201
(1200 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54EH1|EPN_DICDI Epsin OS=Dictyostelium discoideum GN=epnA PE... 166 3e-040
sp|Q4V882|EPN3_RAT Epsin-3 OS=Rattus norvegicus GN=Epn3 PE=1 SV=1 161 2e-038
sp|O95208|EPN2_HUMAN Epsin-2 OS=Homo sapiens GN=EPN2 PE=1 SV=3 159 6e-038
sp|Q8CHU3|EPN2_MOUSE Epsin-2 OS=Mus musculus GN=Epn2 PE=1 SV=1 157 2e-037
sp|Q9Z1Z3|EPN2_RAT Epsin-2 OS=Rattus norvegicus GN=Epn2 PE=1 SV=1 157 2e-037
sp|Q9H201|EPN3_HUMAN Epsin-3 OS=Homo sapiens GN=EPN3 PE=1 SV=1 156 3e-037
sp|Q9Y6I3|EPN1_HUMAN Epsin-1 OS=Homo sapiens GN=EPN1 PE=1 SV=1 153 3e-036
sp|Q80VP1|EPN1_MOUSE Epsin-1 OS=Mus musculus GN=Epn1 PE=1 SV=3 153 3e-036
sp|O88339|EPN1_RAT Epsin-1 OS=Rattus norvegicus GN=Epn1 PE=1 SV=1 153 3e-036
sp|Q91W69|EPN3_MOUSE Epsin-3 OS=Mus musculus GN=Epn3 PE=2 SV=1 153 4e-036
sp|A7Z035|EPN4_BOVIN Clathrin interactor 1 OS=Bos taurus GN=CLIN... 144 1e-033
sp|Q14677|EPN4_HUMAN Clathrin interactor 1 OS=Homo sapiens GN=CL... 144 1e-033
sp|Q99KN9|EPN4_MOUSE Clathrin interactor 1 OS=Mus musculus GN=Cl... 141 2e-032
sp|P78813|YCTB_SCHPO ENTH domain-containing protein C794.11c OS=... 137 2e-031
sp|O74423|ENT1_SCHPO Epsin-1 OS=Schizosaccharomyces pombe GN=ent... 134 2e-030
sp|P47160|ENT3_YEAST Epsin-3 OS=Saccharomyces cerevisiae GN=ENT3... 131 1e-029
sp|Q8IYW4|ENTD1_HUMAN ENTH domain-containing protein 1 OS=Homo s... 131 1e-029
sp|Q05785|ENT2_YEAST Epsin-2 OS=Saccharomyces cerevisiae GN=ENT2... 105 1e-021
sp|Q12518|ENT1_YEAST Epsin-1 OS=Saccharomyces cerevisiae GN=ENT1... 94 2e-018
>sp|Q54EH1|EPN_DICDI Epsin OS=Dictyostelium discoideum GN=epnA PE=3 SV=1
Length = 686
Score = 166 bits (420), Expect = 3e-040
Identities = 93/249 (37%), Positives = 147/249 (59%), Gaps = 24/249 (9%)
Frame = +1
Query: 295 VLKVPGIEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIWKRLSDTGKNWRH 474
VL P IE+KV DATSN+ WGP G+ + ++++AS NY + +IMGVIWKR++D GK WRH
Sbjct: 16 VLNTPEIERKVRDATSNDKWGPSGTQMQEISRASYNYECFPIIMGVIWKRINDPGKFWRH 75
Query: 475 VYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGSNVRKKSQSLVAL 654
VYK+L +++Y+V +GS +VI + R +I TL +FQYI+ +D G +VR++++ ++ L
Sbjct: 76 VYKSLLLIDYLVRNGSPQVIRDCRHHTMEIKTLVEFQYIEE-EKDVGLSVRERAKQVIDL 134
Query: 655 VNDKERIAEVSEKAAANRDKY-------RSSAPGGMYKPSGGYGDRYDYGSRDDERSSYG 813
+ D +RI E +KA N++KY R GG GGY D YGS ++R SYG
Sbjct: 135 LQDDQRIKEERDKAKTNQNKYVGIGNDSRDFGYGGGSYGGGGY-DSDSYGS--NQRDSYG 191
Query: 814 REREYGYRDDDRNSRDGDRYSEDRYGRDGNREDDYRGRSKSVDNFPHSSRGRSSGRERTF 993
+ Y + R+S G++ R+ R D + GR + N ++ ++
Sbjct: 192 GNQRDSYGGNQRDSYGGNQ-------RETTRRDSFNGRDEGYGN------NNNNNNNNSY 238
Query: 994 EDDGHSSSR 1020
+ D +S++R
Sbjct: 239 DSDPYSNTR 247
>sp|Q4V882|EPN3_RAT Epsin-3 OS=Rattus norvegicus GN=Epn3 PE=1 SV=1
Length = 608
Score = 161 bits (405), Expect = 2e-038
Identities = 97/245 (39%), Positives = 142/245 (57%), Gaps = 5/245 (2%)
Frame = +1
Query: 259 TVRDLKREVNKKVLKVPGIEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIW 438
T L+R+V V E KV +ATSN+PWGP SL++++A + N + +MG++W
Sbjct: 2 TTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVW 61
Query: 439 KRLSDTGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGS 618
+RL+D+GKNWRHVYKALT+L+Y++ GSERV + RE Y I TL DFQYID G+DQG
Sbjct: 62 RRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGV 121
Query: 619 NVRKKSQSLVALVNDKERIAEVSEKAAANRDKYRSSAPGGMYKPSGGYG-DRYDYGSRDD 795
NVR+K + ++AL+ D+ER+ + E+ A + K R A GM SG G R GS
Sbjct: 122 NVREKVKQVMALLKDEERLRQ--ERTHALKTKER-MALEGMGIGSGQLGFSRRSRGSPSS 178
Query: 796 ERSSYGREREYGYRDDDRNSRDGDRYSEDRYGRDGNRED-DYRGRSKSVDNFPHSSRGRS 972
S+ R + R G+ + + +RE+ + GRS D+FP ++
Sbjct: 179 YTSASSSPRYASDLEQARPQTSGEEELQLQLALAMSREEAEKGGRSWKGDDFPVANGAEP 238
Query: 973 SGRER 987
+G+ R
Sbjct: 239 AGQRR 243
>sp|O95208|EPN2_HUMAN Epsin-2 OS=Homo sapiens GN=EPN2 PE=1 SV=3
Length = 641
Score = 159 bits (400), Expect = 6e-038
Identities = 82/191 (42%), Positives = 115/191 (60%), Gaps = 5/191 (2%)
Frame = +1
Query: 259 TVRDLKREVNKKVLKVPGIEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIW 438
T ++R++ V E KV +ATSN+PWGP SL+ ++A + N + IM ++W
Sbjct: 2 TTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVW 61
Query: 439 KRLSDTGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGS 618
KRL+D GKNWRHVYKALT+L+Y++ GSERV + RE + I TL DFQYID G+DQG
Sbjct: 62 KRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGI 121
Query: 619 NVRKKSQSLVALVNDKERIAEVSEKAAANRDKYRSSAPGGMYKPSGGYGDRYDYGSRDDE 798
NVR+KS+ LVAL+ D+ER+ +A +++ A G G + GS
Sbjct: 122 NVREKSKQLVALLKDEERLKAERAQALKTKERMAQVATG-----MGSNQITFGRGSSQPN 176
Query: 799 RSSYGREREYG 831
S+ E+EYG
Sbjct: 177 LSTSHSEQEYG 187
>sp|Q8CHU3|EPN2_MOUSE Epsin-2 OS=Mus musculus GN=Epn2 PE=1 SV=1
Length = 595
Score = 157 bits (396), Expect = 2e-037
Identities = 82/191 (42%), Positives = 115/191 (60%), Gaps = 5/191 (2%)
Frame = +1
Query: 259 TVRDLKREVNKKVLKVPGIEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIW 438
T ++R++ V E KV +ATSN+PWGP SL+ ++A + N + IM ++W
Sbjct: 2 TTSSIRRQMKNIVNNYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVAFSEIMSMVW 61
Query: 439 KRLSDTGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGS 618
KRL+D GKNWRHVYKALT+L+Y++ GSERV + RE + I TL DFQYID G+DQG
Sbjct: 62 KRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGI 121
Query: 619 NVRKKSQSLVALVNDKERIAEVSEKAAANRDKYRSSAPGGMYKPSGGYGDRYDYGSRDDE 798
NVR+KS+ LVAL+ D+ER+ +A +++ A G G + GS
Sbjct: 122 NVREKSKQLVALLKDEERLKVERVQALKTKERMAQVATG-----VGSNQITFGRGSSQPN 176
Query: 799 RSSYGREREYG 831
S+ E+EYG
Sbjct: 177 LSTSYSEQEYG 187
>sp|Q9Z1Z3|EPN2_RAT Epsin-2 OS=Rattus norvegicus GN=Epn2 PE=1 SV=1
Length = 583
Score = 157 bits (395), Expect = 2e-037
Identities = 82/191 (42%), Positives = 114/191 (59%), Gaps = 5/191 (2%)
Frame = +1
Query: 259 TVRDLKREVNKKVLKVPGIEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIW 438
T ++R++ V E KV +ATSN+PWGP SL+ ++A + N + IM ++W
Sbjct: 2 TTSSIRRQMKNIVNSYSEAEIKVREATSNDPWGPSSSLMTEIADLTYNVVRFSEIMSMVW 61
Query: 439 KRLSDTGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGS 618
KRL+D GKNWRHVYKALT+L+Y++ GSERV + RE + I TL DFQYID G+DQG
Sbjct: 62 KRLNDHGKNWRHVYKALTLLDYLIKTGSERVAQQCRENIFAIQTLKDFQYIDRDGKDQGI 121
Query: 619 NVRKKSQSLVALVNDKERIAEVSEKAAANRDKYRSSAPGGMYKPSGGYGDRYDYGSRDDE 798
NVR+KS+ LVAL+ D+ER+ +A +++ A G G + GS
Sbjct: 122 NVREKSKQLVALLKDEERLKVERVQALKTKERMAQVATG-----VGSNQITFGRGSSQPN 176
Query: 799 RSSYGREREYG 831
S E+EYG
Sbjct: 177 LSISHSEQEYG 187
>sp|Q9H201|EPN3_HUMAN Epsin-3 OS=Homo sapiens GN=EPN3 PE=1 SV=1
Length = 632
Score = 156 bits (394), Expect = 3e-037
Identities = 84/187 (44%), Positives = 119/187 (63%), Gaps = 5/187 (2%)
Frame = +1
Query: 259 TVRDLKREVNKKVLKVPGIEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIW 438
T L+R+V V E KV +ATSN+PWGP SL++++A + N + +MG++W
Sbjct: 2 TTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGMLW 61
Query: 439 KRLSDTGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGS 618
+RL+D+GKNWRHVYKALT+L+Y++ GSERV + RE Y I TL DFQYID G+DQG
Sbjct: 62 RRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGV 121
Query: 619 NVRKKSQSLVALVNDKERIAEVSEKAAANRDKYRSSAPG-GMYKPSGGYGDRY--DYGSR 789
NVR+K + ++AL+ D+ER+ + E+ A + K R + G G+ G+ RY DY
Sbjct: 122 NVREKVKQVMALLKDEERLRQ--ERTHALKTKERMALEGIGIGSGQLGFSRRYGEDYSRS 179
Query: 790 DDERSSY 810
SSY
Sbjct: 180 RGSPSSY 186
>sp|Q9Y6I3|EPN1_HUMAN Epsin-1 OS=Homo sapiens GN=EPN1 PE=1 SV=1
Length = 551
Score = 153 bits (385), Expect = 3e-036
Identities = 71/153 (46%), Positives = 104/153 (67%)
Frame = +1
Query: 271 LKREVNKKVLKVPGIEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIWKRLS 450
L+R++ V E KV +ATSN+PWGP SL++++A + N + IM +IWKRL+
Sbjct: 6 LRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLN 65
Query: 451 DTGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGSNVRK 630
D GKNWRHVYKA+T++EY++ GSERV + +E Y + TL DFQY+D G+DQG NVR+
Sbjct: 66 DHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVRE 125
Query: 631 KSQSLVALVNDKERIAEVSEKAAANRDKYRSSA 729
K++ LVAL+ D++R+ E A ++K +A
Sbjct: 126 KAKQLVALLRDEDRLREERAHALKTKEKLAQTA 158
>sp|Q80VP1|EPN1_MOUSE Epsin-1 OS=Mus musculus GN=Epn1 PE=1 SV=3
Length = 575
Score = 153 bits (385), Expect = 3e-036
Identities = 71/153 (46%), Positives = 104/153 (67%)
Frame = +1
Query: 271 LKREVNKKVLKVPGIEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIWKRLS 450
L+R++ V E KV +ATSN+PWGP SL++++A + N + IM +IWKRL+
Sbjct: 6 LRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLN 65
Query: 451 DTGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGSNVRK 630
D GKNWRHVYKA+T++EY++ GSERV + +E Y + TL DFQY+D G+DQG NVR+
Sbjct: 66 DHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVRE 125
Query: 631 KSQSLVALVNDKERIAEVSEKAAANRDKYRSSA 729
K++ LVAL+ D++R+ E A ++K +A
Sbjct: 126 KAKQLVALLRDEDRLREERAHALKTKEKLAQTA 158
>sp|O88339|EPN1_RAT Epsin-1 OS=Rattus norvegicus GN=Epn1 PE=1 SV=1
Length = 575
Score = 153 bits (385), Expect = 3e-036
Identities = 71/153 (46%), Positives = 104/153 (67%)
Frame = +1
Query: 271 LKREVNKKVLKVPGIEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIWKRLS 450
L+R++ V E KV +ATSN+PWGP SL++++A + N + IM +IWKRL+
Sbjct: 6 LRRQMKNIVHNYSEAEIKVREATSNDPWGPSSSLMSEIADLTYNVVAFSEIMSMIWKRLN 65
Query: 451 DTGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGSNVRK 630
D GKNWRHVYKA+T++EY++ GSERV + +E Y + TL DFQY+D G+DQG NVR+
Sbjct: 66 DHGKNWRHVYKAMTLMEYLIKTGSERVSQQCKENMYAVQTLKDFQYVDRDGKDQGVNVRE 125
Query: 631 KSQSLVALVNDKERIAEVSEKAAANRDKYRSSA 729
K++ LVAL+ D++R+ E A ++K +A
Sbjct: 126 KAKQLVALLRDEDRLREERAHALKTKEKLAQTA 158
>sp|Q91W69|EPN3_MOUSE Epsin-3 OS=Mus musculus GN=Epn3 PE=2 SV=1
Length = 636
Score = 153 bits (384), Expect = 4e-036
Identities = 79/172 (45%), Positives = 113/172 (65%), Gaps = 3/172 (1%)
Frame = +1
Query: 259 TVRDLKREVNKKVLKVPGIEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIW 438
T L+R+V V E KV +ATSN+PWGP SL++++A + N + +MG++W
Sbjct: 2 TTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVW 61
Query: 439 KRLSDTGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGS 618
+RL+D+GKNWRHVYKALT+L+Y++ GSERV + RE Y I TL DFQYID G+DQG
Sbjct: 62 RRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGV 121
Query: 619 NVRKKSQSLVALVNDKERIAEVSEKAAANRDKYRSSAPG-GMYKPSGGYGDR 771
NVR+K + ++AL+ D+ER+ + E+ A + K R + G G+ GY R
Sbjct: 122 NVREKVKQVMALLKDEERLRQ--ERTHALKTKERMALEGMGIGSGQLGYSRR 171
>sp|A7Z035|EPN4_BOVIN Clathrin interactor 1 OS=Bos taurus GN=CLINT1 PE=2 SV=1
Length = 643
Score = 144 bits (363), Expect = 1e-033
Identities = 89/258 (34%), Positives = 138/258 (53%), Gaps = 22/258 (8%)
Frame = +1
Query: 262 VRDLKREVNKKVLKVPGIEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIWK 441
VR+L + V+ IE KV +AT+++PWGP G L+ ++A+A+ Y ++ +M ++W
Sbjct: 7 VRELVDKATNVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWS 66
Query: 442 R-LSDTGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGS 618
R L D KNWR VYK+L +L Y++ +GSERV+ RE Y + +L ++ ++D G+DQG
Sbjct: 67 RMLKDNKKNWRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGI 126
Query: 619 NVRKKSQSLVALVNDKERIAEVSEKAAANRDKY---RSSAPGGMYKPSGGYGDRYDYGSR 789
N+R+K + LV D +R+ E +KA N+DKY S + GG Y +RYD +
Sbjct: 127 NIRQKVKELVEFAQDDDRLREERKKAKKNKDKYVGVSSDSVGGF-----RYSERYDPEPK 181
Query: 790 -------DDERSSYGREREYGYRDDDRNSRDGDRYSEDRYGRDGNREDDYRGRSKSVDNF 948
D +S++ + G D S D S+ R +RED R D
Sbjct: 182 SKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISK---FRRKDREDSPE-RCSDSDEE 237
Query: 949 PHSSRGRSSGRERTFEDD 1002
+ RGRS E F+D+
Sbjct: 238 KKARRGRSPKGE--FKDE 253
>sp|Q14677|EPN4_HUMAN Clathrin interactor 1 OS=Homo sapiens GN=CLINT1 PE=1 SV=1
Length = 625
Score = 144 bits (363), Expect = 1e-033
Identities = 89/258 (34%), Positives = 138/258 (53%), Gaps = 22/258 (8%)
Frame = +1
Query: 262 VRDLKREVNKKVLKVPGIEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIWK 441
VR+L + V+ IE KV +AT+++PWGP G L+ ++A+A+ Y ++ +M ++W
Sbjct: 7 VRELVDKATNVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWS 66
Query: 442 R-LSDTGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGS 618
R L D KNWR VYK+L +L Y++ +GSERV+ RE Y + +L ++ ++D G+DQG
Sbjct: 67 RMLKDNKKNWRRVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGI 126
Query: 619 NVRKKSQSLVALVNDKERIAEVSEKAAANRDKY---RSSAPGGMYKPSGGYGDRYDYGSR 789
N+R+K + LV D +R+ E +KA N+DKY S + GG Y +RYD +
Sbjct: 127 NIRQKVKELVEFAQDDDRLREERKKAKKNKDKYVGVSSDSVGGF-----RYSERYDPEPK 181
Query: 790 -------DDERSSYGREREYGYRDDDRNSRDGDRYSEDRYGRDGNREDDYRGRSKSVDNF 948
D +S++ + G D S D S+ R +RED R D
Sbjct: 182 SKWDEEWDKNKSAFPFSDKLGELSDKIGSTIDDTISK---FRRKDREDSPE-RCSDSDEE 237
Query: 949 PHSSRGRSSGRERTFEDD 1002
+ RGRS E F+D+
Sbjct: 238 KKARRGRSPKGE--FKDE 253
>sp|Q99KN9|EPN4_MOUSE Clathrin interactor 1 OS=Mus musculus GN=Clint1 PE=1 SV=2
Length = 631
Score = 141 bits (353), Expect = 2e-032
Identities = 86/247 (34%), Positives = 133/247 (53%), Gaps = 22/247 (8%)
Frame = +1
Query: 295 VLKVPGIEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIWKR-LSDTGKNWR 471
V+ IE KV +AT+++PWGP G L+ ++A+A+ Y ++ +M ++W R L D KNWR
Sbjct: 26 VMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKNWR 85
Query: 472 HVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGSNVRKKSQSLVA 651
VYK+L +L Y++ +GSERV+ RE Y + +L ++ ++D G+DQG N+R+K + LV
Sbjct: 86 RVYKSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKELVE 145
Query: 652 LVNDKERIAEVSEKAAANRDKY---RSSAPGGMYKPSGGYGDRYDYGSR-------DDER 801
D +R+ E +KA N+DKY S + GG Y +RYD + D +
Sbjct: 146 FAQDDDRLREERKKAKKNKDKYVGVSSDSVGGF-----RYNERYDPEPKSKWDEEWDKNK 200
Query: 802 SSYGREREYGYRDDDRNSRDGDRYSEDRYGRDGNREDDYRGRSKSVDNFPHSSRGRSSGR 981
S++ + G D S D S+ R +RED R D + RGRS
Sbjct: 201 SAFPFSDKLGELSDKIGSTIDDTISK---FRRKDREDSPE-RCSDSDEEKKARRGRSPKG 256
Query: 982 ERTFEDD 1002
E F+D+
Sbjct: 257 E--FKDE 261
>sp|P78813|YCTB_SCHPO ENTH domain-containing protein C794.11c
OS=Schizosaccharomyces pombe GN=SPCC794.11c PE=1 SV=2
Length = 476
Score = 137 bits (343), Expect = 2e-031
Identities = 86/275 (31%), Positives = 138/275 (50%), Gaps = 13/275 (4%)
Frame = +1
Query: 238 MKKVFGQTVRDLKREVNKKVLKVPGIEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQ 417
MK + ++ R+ V+ +E +V +AT+NEPWG SL+ ++AQ + NY +
Sbjct: 8 MKNINLYDIKAAVRKAQNVVMNYTSMEARVREATNNEPWGASTSLMMEIAQGTHNYSQLN 67
Query: 418 LIMGVIWKRLSD-TGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYID 594
I+ +I++R ++ T + WR +YKAL +LE++V +GSERV+D+ R I L +F YID
Sbjct: 68 EILPMIYRRFTEKTAEEWRQIYKALQLLEFLVKNGSERVVDDARAHQATIKMLRNFHYID 127
Query: 595 SGGRDQGSNVRKKSQSLVALVNDKERIAEVSEKAAANRDKYRSSAPGGMYKPSGGYGDRY 774
+DQG NVR +++ LV L+ND ERI + ++A NR K+ G + S R+
Sbjct: 128 HRQKDQGLNVRTRAKELVELLNDSERIRKERKRARQNRGKFIGVGSDGDSRISTSSKSRF 187
Query: 775 -DYGSRDDERSSY--------GREREYGYRDDDRNSRDGDRYSEDRYGRDGNREDDYRGR 927
+GS R SY G +YG D +S R + D + N + D
Sbjct: 188 PSFGS---SRGSYRTRVYGDGGGFTDYGNGYHDSSSMSDSRDASDNDVEEYNEDGDGGSS 244
Query: 928 SKSVDNFPHSSRGRSSGRERTFEDDGHSSSRYVDL 1032
+ N SR ++ + + S +DL
Sbjct: 245 DAATANSTRGSRRTTTKQSDKAPEQPKQESAMIDL 279
>sp|O74423|ENT1_SCHPO Epsin-1 OS=Schizosaccharomyces pombe GN=ent1 PE=1 SV=1
Length = 706
Score = 134 bits (336), Expect = 2e-030
Identities = 80/234 (34%), Positives = 127/234 (54%), Gaps = 17/234 (7%)
Frame = +1
Query: 322 KVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIWKRLSDTGKNWRHVYKALTVLE 501
KV +AT+N+ WGP G+ +A++A+ + + +E +M +I +RL+D GKNWRHV+K+L++LE
Sbjct: 25 KVRNATTNDSWGPSGTAMAEIAELTYDQNEMLEVMDIIDRRLNDKGKNWRHVFKSLSLLE 84
Query: 502 YMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGSNVRKKSQSLVALVNDKERIAE 681
Y + +GSE V+ ++ Y I+TL +F Y+D G DQG NVR K++ + +L+ D+ + E
Sbjct: 85 YCLHNGSENVVRWAKDNIYIITTLREFVYVDDNGHDQGQNVRTKAKEITSLLEDEHALKE 144
Query: 682 V---SEKAAANRDKYRSSAPGGMYKPSGGYGDRYDYGSRDDERSSYGREREYGYRDDDRN 852
S + +RD+ RSS + DR Y ++ R S R Y DDDR+
Sbjct: 145 ARGDSRERDRDRDRTRSS------RFDDDDDDRAPY---EESRLSRAPSRASRYDDDDRD 195
Query: 853 SRDGDRYSEDRYGRDGNREDDYR-----GRSKSVDNFPHSSRGRSSGRERTFED 999
R R R GR +R R + + +N P R + + ED
Sbjct: 196 HRSRRRSRSRRPGRSRSRRRSRRPSPSAEHNSAEENDPELQRVIEESKRQAEED 249
>sp|P47160|ENT3_YEAST Epsin-3 OS=Saccharomyces cerevisiae GN=ENT3 PE=1 SV=1
Length = 408
Score = 131 bits (329), Expect = 1e-029
Identities = 81/248 (32%), Positives = 128/248 (51%), Gaps = 14/248 (5%)
Frame = +1
Query: 277 REVNKKVLKVPGIEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIWKRLSD- 453
R+ V +E KV +AT+NEPWG +L+ ++Q + N+ E + I+ +I++R ++
Sbjct: 20 RKAQNVVFNYTEMEGKVREATNNEPWGASSTLMDQISQGTYNFREREEILSMIFRRFTEK 79
Query: 454 TGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGSNVRKK 633
G WR +YKAL +L+Y++ HGSER ID+ R I L F YIDS GRDQG NVR +
Sbjct: 80 AGSEWRQIYKALQLLDYLIKHGSERFIDDTRNSINLIRILETFHYIDSQGRDQGINVRTR 139
Query: 634 SQSLVALVNDKERIAEVSEKAAANRDKYRSSAPGGMYKPSGGYGDRYDYGSRDDERSSYG 813
++L+ L++D +I +KA KY+ A GG G + + S +G
Sbjct: 140 VKALIELLSDDNKIRAERKKARETAKKYKGVA-GGSASADGSLNSKAGFTS----TKVHG 194
Query: 814 REREYGYRDDDRNSRDGDRYSEDRYGRDGNREDDYRGRSKS-----VDNFPHSSRGRSSG 978
+ D+ ++ DG +S++ Y + +R G+ K VD F SS
Sbjct: 195 ISVSADFDSDNEDNEDGS-FSQNGYNDNASRATSTPGQGKQEPEDFVDFF--SSESSKPS 251
Query: 979 RERTFEDD 1002
+E ED+
Sbjct: 252 KELIQEDE 259
>sp|Q8IYW4|ENTD1_HUMAN ENTH domain-containing protein 1 OS=Homo sapiens
GN=ENTHD1 PE=2 SV=1
Length = 607
Score = 131 bits (329), Expect = 1e-029
Identities = 61/147 (41%), Positives = 94/147 (63%)
Frame = +1
Query: 274 KREVNKKVLKVPGIEQKVLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIWKRLSD 453
+R+V V E KV +ATSN+PWGP SL+ D++ + N IM ++W RL+D
Sbjct: 4 RRQVKNFVKNYSDAEIKVREATSNDPWGPSSSLMLDISDLTFNTISLSEIMNMLWHRLND 63
Query: 454 TGKNWRHVYKALTVLEYMVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGSNVRKK 633
GKNWRHVYK+LT+++Y++ +GS++VI RE + TL DFQ+ID G+DQG +R+K
Sbjct: 64 HGKNWRHVYKSLTLMDYLIKNGSKKVIQHCREGFCNLQTLKDFQHIDEAGKDQGYYIREK 123
Query: 634 SQSLVALVNDKERIAEVSEKAAANRDK 714
S+ ++ L+ D+ + + E A R +
Sbjct: 124 SKQVITLLMDEPLLCKEREVACRTRQR 150
>sp|Q05785|ENT2_YEAST Epsin-2 OS=Saccharomyces cerevisiae GN=ENT2 PE=1 SV=1
Length = 613
Score = 105 bits (260), Expect = 1e-021
Identities = 58/136 (42%), Positives = 84/136 (61%)
Frame = +1
Query: 325 VLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIWKRLSDTGKNWRHVYKALTVLEY 504
V DAT+N+ P L DLAQ S + ++ IM ++ KRL+D GK WRHV K+LTVL+Y
Sbjct: 23 VRDATANDSRTPSIDTLDDLAQRSYDSVDFFEIMDMLDKRLNDKGKYWRHVAKSLTVLDY 82
Query: 505 MVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGSNVRKKSQSLVALVNDKERIAEV 684
+V GSE + RE Y I TL +F++ + G D+G +R K++ LV+L+ND+ER+ E
Sbjct: 83 LVRFGSENCVLWCRENFYVIKTLREFRHENESGFDEGQIIRVKAKELVSLLNDEERLREE 142
Query: 685 SEKAAANRDKYRSSAP 732
NR R++ P
Sbjct: 143 RSMNTRNRRANRAARP 158
>sp|Q12518|ENT1_YEAST Epsin-1 OS=Saccharomyces cerevisiae GN=ENT1 PE=1 SV=1
Length = 454
Score = 94 bits (231), Expect = 2e-018
Identities = 51/119 (42%), Positives = 75/119 (63%)
Frame = +1
Query: 325 VLDATSNEPWGPHGSLLADLAQASRNYHEYQLIMGVIWKRLSDTGKNWRHVYKALTVLEY 504
V +ATSN+ L +LA+ S + ++ IM ++ KRL+D GK WRH+ KALTV++Y
Sbjct: 23 VRNATSNDNHQVSKDSLIELAEKSYDSADFFEIMDMLDKRLNDKGKYWRHIAKALTVIDY 82
Query: 505 MVGHGSERVIDEIRERAYQISTLSDFQYIDSGGRDQGSNVRKKSQSLVALVNDKERIAE 681
++ GSE + RE Y I TL +F++ D G DQG VR K++ L AL++D ER+ E
Sbjct: 83 LIRFGSENCVLWCRENLYIIKTLKEFRHEDDEGIDQGQIVRVKAKELTALLSDDERLNE 141
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,745,191,639
Number of Sequences: 518415
Number of Extensions: 102745191639
Number of Successful Extensions: 656160410
Number of sequences better than 0.0: 0
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