BLASTX 7.6.2
Query= UN24965 /QuerySize=1111
(1110 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|A5YKK6|CNOT1_HUMAN CCR4-NOT transcription complex subunit 1 O... 78 9e-014
sp|P87112|NOT1_SCHPO General negative regulator of transcription... 78 9e-014
sp|A0JP85|CNOT1_XENTR CCR4-NOT transcription complex subunit 1 O... 77 2e-013
sp|Q6ZQ08|CNOT1_MOUSE CCR4-NOT transcription complex subunit 1 O... 77 3e-013
sp|A1A5H6|CNOT1_DANRE CCR4-NOT transcription complex subunit 1 O... 72 5e-012
sp|P25655|NOT1_YEAST General negative regulator of transcription... 69 5e-011
>sp|A5YKK6|CNOT1_HUMAN CCR4-NOT transcription complex subunit 1 OS=Homo sapiens
GN=CNOT1 PE=1 SV=2
Length = 2376
Score = 78 bits (191), Expect = 9e-014
Identities = 46/140 (32%), Positives = 77/140 (55%), Gaps = 3/140 (2%)
Frame = +1
Query: 562 LKSLGAWLGKFIVTTKGSLSKFDIDLKSLVVEAYQLGL--LSKTLPFVLEFLEPCSKSPF 735
LK+LG WLG + + D+D+KSL++EAY G L +PFV + LE +S
Sbjct: 1192 LKNLGHWLGMITLAKNKPILHTDLDVKSLLLEAYVKGQQELLYVVPFVAKVLESSIRSVV 1251
Query: 736 YTHSNPWTMMILKLLYEIYIMSNMQDNLRLSIEGLLEKFGV-LEQLKPSSILQKKHRKRD 912
+ NPWTM I+ +L E++ +++ NL+ IE L + + + +LKP ++L+ K R ++
Sbjct: 1252 FRPPNPWTMAIMNVLAELHQEHDLKLNLKFEIEVLCKNLALDINELKPGNLLKDKDRLKN 1311
Query: 913 RSDVHIPMAKAIKNPLDSAP 972
+ K +K P + P
Sbjct: 1312 LDEQLSAPKKDVKQPEELPP 1331
>sp|P87112|NOT1_SCHPO General negative regulator of transcription subunit 1
OS=Schizosaccharomyces pombe GN=not1 PE=1 SV=1
Length = 2100
Score = 78 bits (191), Expect = 9e-014
Identities = 48/165 (29%), Positives = 83/165 (50%), Gaps = 5/165 (3%)
Frame = +1
Query: 562 LKSLGAWLGKFIVTTKGSLSKFDIDLKSLVVEAYQLGLLSKTLPFVLEFLEPCSKSPFYT 741
LK+LG+WLG + ++ + K L++E G + + LPFV + LE S S +
Sbjct: 964 LKNLGSWLGSITLLRNKPITTLQVSFKDLLLEGIDSGRIDRVLPFVCKVLEKASSSVIFK 1023
Query: 742 HSNPWTMMILKLLYEIYIMSNMQDNLRLSIEGLLEKFGV-LEQLKPSSILQKKHRKRDRS 918
NPW M ILKLL E+Y ++ + NL+ IE LL V ++ ++PS + ++ ++
Sbjct: 1024 PPNPWLMGILKLLVELYQFADFRLNLKFEIELLLNNLNVKMDNIEPSEMY--RNHLVQKA 1081
Query: 919 DVHIPMAKAIKNPLDSAPDRVDLLRYSRDKFSEEFLVTIKTSRSF 1053
D+ + + + N PD D++ S + VT ++ F
Sbjct: 1082 DLEKELPEDVLNA--EFPDGTDVITQYIVAASSQITVTDAVAQVF 1124
>sp|A0JP85|CNOT1_XENTR CCR4-NOT transcription complex subunit 1 OS=Xenopus
tropicalis GN=cnot1 PE=2 SV=1
Length = 2388
Score = 77 bits (188), Expect = 2e-013
Identities = 47/140 (33%), Positives = 75/140 (53%), Gaps = 3/140 (2%)
Frame = +1
Query: 562 LKSLGAWLGKFIVTTKGSLSKFDIDLKSLVVEAYQLGL--LSKTLPFVLEFLEPCSKSPF 735
LK+LG WLG + + D+DLKSL++EAY G L +PFV + LE +S
Sbjct: 1178 LKNLGHWLGMITLAKNKPILHTDLDLKSLLLEAYVKGQQELLYVVPFVAKVLESSVRSVV 1237
Query: 736 YTHSNPWTMMILKLLYEIYIMSNMQDNLRLSIEGLLEKFGV-LEQLKPSSILQKKHRKRD 912
+ NPWTM I+ +L E++ +++ NL+ IE L + + + LKP ++L+ K R +
Sbjct: 1238 FRPPNPWTMAIMNVLAELHQEHDLKLNLKFEIEVLCKNLVLDINDLKPGTLLKDKDRLKS 1297
Query: 913 RSDVHIPMAKAIKNPLDSAP 972
+ K +K P + P
Sbjct: 1298 LDEQLSAPKKDVKQPEELPP 1317
>sp|Q6ZQ08|CNOT1_MOUSE CCR4-NOT transcription complex subunit 1 OS=Mus musculus
GN=Cnot1 PE=1 SV=2
Length = 2375
Score = 77 bits (187), Expect = 3e-013
Identities = 45/135 (33%), Positives = 75/135 (55%), Gaps = 3/135 (2%)
Frame = +1
Query: 562 LKSLGAWLGKFIVTTKGSLSKFDIDLKSLVVEAYQLGL--LSKTLPFVLEFLEPCSKSPF 735
LK+LG WLG + + D+D+KSL++EAY G L +PFV + LE +S
Sbjct: 1191 LKNLGHWLGMITLAKNKPILHTDLDVKSLLLEAYVKGQQELLYVVPFVAKVLESSIRSLV 1250
Query: 736 YTHSNPWTMMILKLLYEIYIMSNMQDNLRLSIEGLLEKFGV-LEQLKPSSILQKKHRKRD 912
+ NPWTM I+ +L E++ +++ NL+ IE L + + + +LKP ++L+ K R ++
Sbjct: 1251 FRPPNPWTMAIMNVLAELHQEHDLKLNLKFEIEVLCKNLALDINELKPGNLLKDKDRLKN 1310
Query: 913 RSDVHIPMAKAIKNP 957
+ K +K P
Sbjct: 1311 LDEQLSAPKKDVKQP 1325
>sp|A1A5H6|CNOT1_DANRE CCR4-NOT transcription complex subunit 1 OS=Danio rerio
GN=cnot1 PE=2 SV=1
Length = 2374
Score = 72 bits (176), Expect = 5e-012
Identities = 45/140 (32%), Positives = 74/140 (52%), Gaps = 3/140 (2%)
Frame = +1
Query: 562 LKSLGAWLGKFIVTTKGSLSKFDIDLKSLVVEAYQLGL--LSKTLPFVLEFLEPCSKSPF 735
LK+LG WLG + + D++LKSL++EAY G L +PFV + LE +S
Sbjct: 1184 LKNLGHWLGMITLAKNKPILYTDLELKSLLLEAYVKGQQELLYVVPFVAKVLESSLRSVI 1243
Query: 736 YTHSNPWTMMILKLLYEIYIMSNMQDNLRLSIEGLLEKFGV-LEQLKPSSILQKKHRKRD 912
+ NPWTM I+ +L E++ +++ NL+ IE L + + + LKP ++L+ K + +
Sbjct: 1244 FRPQNPWTMGIMNVLAELHQEHDLKLNLKFEIEVLCKNLSMDITDLKPGNLLRDKDKLKT 1303
Query: 913 RSDVHIPMAKAIKNPLDSAP 972
+ K K P + P
Sbjct: 1304 LEEQLSAPKKETKPPEELLP 1323
>sp|P25655|NOT1_YEAST General negative regulator of transcription subunit 1
OS=Saccharomyces cerevisiae GN=NOT1 PE=1 SV=2
Length = 2108
Score = 69 bits (167), Expect = 5e-011
Identities = 37/110 (33%), Positives = 63/110 (57%), Gaps = 1/110 (0%)
Frame = +1
Query: 562 LKSLGAWLGKFIVTTKGSLSKFDIDLKSLVVEAYQLGLLSKTLPFVLEFLEPCSKSPFYT 741
LK+L +WLG + + +I + +++EAY+ L +PFV + L+ S+S +
Sbjct: 880 LKNLASWLGCITLALNKPIKHKNIAFREMLIEAYKENRLEIVVPFVTKILQRASESKIFK 939
Query: 742 HSNPWTMMILKLLYEIYIMSNMQDNLRLSIEGLLEKFGV-LEQLKPSSIL 888
NPWT+ ILKLL E+ +N + +L +E LL+ F + + LKPS+ +
Sbjct: 940 PPNPWTVGILKLLIELNEKANWKLSLTFEVEVLLKSFNLTTKSLKPSNFI 989
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,745,191,639
Number of Sequences: 518415
Number of Extensions: 102745191639
Number of Successful Extensions: 656160410
Number of sequences better than 0.0: 0
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