BLASTX 7.6.2
Query= UN24978 /QuerySize=1227
(1226 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P44573|OPDA_HAEIN Oligopeptidase A OS=Haemophilus influenzae ... 244 1e-063
sp|P27298|OPDA_ECOLI Oligopeptidase A OS=Escherichia coli (strai... 242 4e-063
sp|P27237|OPDA_SALTY Oligopeptidase A OS=Salmonella typhimurium ... 240 2e-062
sp|P24171|DCP_ECOLI Peptidyl-dipeptidase dcp OS=Escherichia coli... 146 5e-034
sp|Q54DD2|THOPL_DICDI Thimet-like oligopeptidase OS=Dictyosteliu... 144 2e-033
sp|P42675|NEUL_RABIT Neurolysin, mitochondrial OS=Oryctolagus cu... 143 4e-033
sp|Q1JPJ8|THOP1_BOVIN Thimet oligopeptidase OS=Bos taurus GN=THO... 142 6e-033
sp|Q8C1A5|THOP1_MOUSE Thimet oligopeptidase OS=Mus musculus GN=T... 142 6e-033
sp|P47788|THOP1_PIG Thimet oligopeptidase OS=Sus scrofa GN=THOP1... 142 6e-033
sp|P27236|DCP_SALTY Peptidyl-dipeptidase dcp OS=Salmonella typhi... 142 7e-033
sp|P24155|THOP1_RAT Thimet oligopeptidase OS=Rattus norvegicus G... 141 1e-032
sp|P52888|THOP1_HUMAN Thimet oligopeptidase OS=Homo sapiens GN=T... 139 4e-032
sp|P25375|PRTD_YEAST Saccharolysin OS=Saccharomyces cerevisiae G... 138 1e-031
sp|Q6CHD6|PMIP_YARLI Mitochondrial intermediate peptidase OS=Yar... 103 4e-021
sp|Q6CVF7|PMIP_KLULA Mitochondrial intermediate peptidase OS=Klu... 97 2e-019
sp|Q753X4|PMIP_ASHGO Mitochondrial intermediate peptidase OS=Ash... 86 5e-016
sp|Q5RF14|MIPEP_PONAB Mitochondrial intermediate peptidase OS=Po... 86 6e-016
>sp|P44573|OPDA_HAEIN Oligopeptidase A OS=Haemophilus influenzae GN=prlC PE=3
SV=1
Length = 681
Score = 244 bits (621), Expect = 1e-063
Identities = 123/248 (49%), Positives = 158/248 (63%), Gaps = 4/248 (1%)
Frame = +1
Query: 349 SVRLPVAQMVCNQTPPVGDKPSLMTFREVETVFHEFGHALQHMLTKEDEGLVAGIRNIEW 528
S+ PVA + CN P+G+KP+L T EV T+FHEFGH + HMLT+ D VAGI + W
Sbjct: 437 SIETPVAYLTCNFNAPIGNKPALFTHNEVTTLFHEFGHGIHHMLTQIDVSDVAGINGVPW 496
Query: 529 DAVELPSQFMENWCYHRDTLMSIAKHYQTGESLPENVYKKLLAARTFRAGSLSLRQLKFA 708
DAVELPSQFMENWC+ + L I+ HY+TGE LP+ +LL A+ F+A LRQL+F
Sbjct: 497 DAVELPSQFMENWCWEEEALAFISGHYETGEPLPKEKLTQLLKAKNFQAAMFILRQLEFG 556
Query: 709 TVDLELHTKYVPGGTESIYDVDQRVSMKTQVIPPLPEDRFLCSFSHIFAGGYAAGYYSYK 888
D LH + T I D + V + VI + R SFSHIFAGGYAAGYYSY
Sbjct: 557 IFDFRLHHTFDAEKTNQILDTLKSVKSQVAVIKGVDWARAPHSFSHIFAGGYAAGYYSYL 616
Query: 889 WAEVLSADAFSAFEDAGLDDIKAVKETGQRFRNTILALGGGKAPLKVFVEFRGREPSPEP 1068
WAEVLSADA+S FE+ G+ + TG+ F + IL GG + P+++F FRGREP +
Sbjct: 617 WAEVLSADAYSRFEEEGIFN----PITGKSFLDEILTRGGSEEPMELFKRFRGREPQLDA 672
Query: 1069 LFRHNGLL 1092
L RH G++
Sbjct: 673 LLRHKGIM 680
Score = 91 bits (224), Expect = 2e-017
Identities = 47/99 (47%), Positives = 60/99 (60%), Gaps = 2/99 (2%)
Frame = +3
Query: 12 LTHWDITFWSERLRESKYDINDEELRPYFSLPKVMDGLFGLAKTLFGIDVAPADGVAPVW 191
L WDI F+SE+ ++ Y INDEELRPYF +V+ GLF L K +F I GV W
Sbjct: 330 LAPWDIGFYSEKQKQHLYAINDEELRPYFPENRVISGLFELIKRIFNIRAVERKGV-DTW 388
Query: 192 NSDVRFYCIKDSSGNPTAYFYFDPYSRPSEKRGGAWMDE 308
+ DVRF+ + D + FY D Y+R KRGGAWMD+
Sbjct: 389 HKDVRFFDLIDENDQLRGSFYLDLYAR-EHKRGGAWMDD 426
>sp|P27298|OPDA_ECOLI Oligopeptidase A OS=Escherichia coli (strain K12) GN=prlC
PE=3 SV=3
Length = 680
Score = 242 bits (617), Expect = 4e-063
Identities = 120/253 (47%), Positives = 161/253 (63%), Gaps = 4/253 (1%)
Frame = +1
Query: 331 MAQKGSSVRLPVAQMVCNQTPPVGDKPSLMTFREVETVFHEFGHALQHMLTKEDEGLVAG 510
M + S++ PVA + CN PV KP+L T EV T+FHEFGH L HMLT+ + V+G
Sbjct: 430 MRKADGSLQKPVAYLTCNFNRPVNGKPALFTHDEVITLFHEFGHGLHHMLTRIETAGVSG 489
Query: 511 IRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYQTGESLPENVYKKLLAARTFRAGSLSL 690
I + WDAVELPSQFMENWC+ + L I+ HY+TGE LP+ + K+LAA+ ++A L
Sbjct: 490 ISGVPWDAVELPSQFMENWCWEPEALAFISGHYETGEPLPKELLDKMLAAKNYQAALFIL 549
Query: 691 RQLKFATVDLELHTKYVPGGTESIYDVDQRVSMKTQVIPPLPEDRFLCSFSHIFAGGYAA 870
RQL+F D LH ++ P I + + V+P RF +FSHIFAGGYAA
Sbjct: 550 RQLEFGLFDFRLHAEFRPDQGAKILETLAEIKKLVAVVPSPSWGRFPHAFSHIFAGGYAA 609
Query: 871 GYYSYKWAEVLSADAFSAFEDAGLDDIKAVKETGQRFRNTILALGGGKAPLKVFVEFRGR 1050
GYYSY WA+VL+ADAFS FE+ G+ + +ETGQ F + IL+ GG + P+ +F FRGR
Sbjct: 610 GYYSYLWADVLAADAFSRFEEEGIFN----RETGQSFLDNILSRGGSEEPMDLFKRFRGR 665
Query: 1051 EPSPEPLFRHNGL 1089
EP + + H G+
Sbjct: 666 EPQLDAMLEHYGI 678
Score = 89 bits (220), Expect = 4e-017
Identities = 44/101 (43%), Positives = 62/101 (61%), Gaps = 2/101 (1%)
Frame = +3
Query: 6 DSLTHWDITFWSERLRESKYDINDEELRPYFSLPKVMDGLFGLAKTLFGIDVAPADGVAP 185
D L WDI ++SE+ ++ Y I+DE+LRPYF K ++GLF + K ++GI V
Sbjct: 327 DELQPWDIAYYSEKQKQHLYSISDEQLRPYFPENKAVNGLFEVVKRIYGITAKERKDV-D 385
Query: 186 VWNSDVRFYCIKDSSGNPTAYFYFDPYSRPSEKRGGAWMDE 308
VW+ DVRF+ + D + FY D Y+R KRGGAWMD+
Sbjct: 386 VWHPDVRFFELYDENNELRGSFYLDLYAR-ENKRGGAWMDD 425
>sp|P27237|OPDA_SALTY Oligopeptidase A OS=Salmonella typhimurium GN=prlC PE=1
SV=1
Length = 680
Score = 240 bits (612), Expect = 2e-062
Identities = 118/253 (46%), Positives = 162/253 (64%), Gaps = 4/253 (1%)
Frame = +1
Query: 331 MAQKGSSVRLPVAQMVCNQTPPVGDKPSLMTFREVETVFHEFGHALQHMLTKEDEGLVAG 510
M + +++ PVA + CN PV KP+L T EV T+FHEFGH L HMLT+ + V+G
Sbjct: 430 MRKADGTLQKPVAYLTCNFNRPVNGKPALFTHDEVITLFHEFGHGLHHMLTRIETAGVSG 489
Query: 511 IRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYQTGESLPENVYKKLLAARTFRAGSLSL 690
I + WDAVELPSQFMENWC+ + L I+ HY+TGE LP+ + K+LAA+ ++A L
Sbjct: 490 ISGVPWDAVELPSQFMENWCWEPEALAFISGHYETGEPLPKELLDKMLAAKNYQAALFIL 549
Query: 691 RQLKFATVDLELHTKYVPGGTESIYDVDQRVSMKTQVIPPLPEDRFLCSFSHIFAGGYAA 870
RQL+F D LH ++ P I + + + V+P RF +FSHIFAGGYAA
Sbjct: 550 RQLEFGLFDFRLHAEFNPQQGAKILETLFEIKKQVAVVPSPTWGRFPHAFSHIFAGGYAA 609
Query: 871 GYYSYKWAEVLSADAFSAFEDAGLDDIKAVKETGQRFRNTILALGGGKAPLKVFVEFRGR 1050
GYYSY WA+VL+ADA+S FE+ G+ + +ETGQ F + IL GG + P+++F FRGR
Sbjct: 610 GYYSYLWADVLAADAYSRFEEEGIFN----RETGQSFLDNILTRGGSEEPMELFKRFRGR 665
Query: 1051 EPSPEPLFRHNGL 1089
EP + + H G+
Sbjct: 666 EPQLDAMLEHYGI 678
Score = 86 bits (212), Expect = 4e-016
Identities = 42/101 (41%), Positives = 62/101 (61%), Gaps = 2/101 (1%)
Frame = +3
Query: 6 DSLTHWDITFWSERLRESKYDINDEELRPYFSLPKVMDGLFGLAKTLFGIDVAPADGVAP 185
+ L WDI ++SE+ ++ Y I+DE+LRPYF K ++GLF + K ++GI V
Sbjct: 327 EELQPWDIAYYSEKQKQHLYSISDEQLRPYFPENKAVNGLFEVVKRIYGITAKERTDV-D 385
Query: 186 VWNSDVRFYCIKDSSGNPTAYFYFDPYSRPSEKRGGAWMDE 308
VW+ +VRF+ + D + FY D Y+R KRGGAWMD+
Sbjct: 386 VWHPEVRFFELYDENNELRGSFYLDLYAR-EHKRGGAWMDD 425
>sp|P24171|DCP_ECOLI Peptidyl-dipeptidase dcp OS=Escherichia coli (strain K12)
GN=dcp PE=1 SV=4
Length = 681
Score = 146 bits (366), Expect = 5e-034
Identities = 78/243 (32%), Positives = 125/243 (51%), Gaps = 6/243 (2%)
Frame = +1
Query: 361 PVAQMVCNQTPPVGDKPSLMTFREVETVFHEFGHALQHMLTKEDEGLVAGIRNIEWDAVE 540
PV VCN P +P+L+ + +V T+FHEFGH L + ++ ++G N D VE
Sbjct: 441 PVIYNVCNYQKPAAGEPALLLWDDVITLFHEFGHTLHGLFARQRYATLSG-TNTPRDFVE 499
Query: 541 LPSQFMENWCYHRDTLMSIAKHYQTGESLPENVYKKLLAARTFRAGSLSLRQLKFATVDL 720
PSQ E+W H A+HYQ+G ++P+ + +K+ A F G L A +D+
Sbjct: 500 FPSQINEHWATHPQVFARYARHYQSGAAMPDELQQKMRNASLFNKGYEMSELLSAALLDM 559
Query: 721 ELHTKYVPGGTESIYDVDQRVSMKTQV-IPPLPEDRFLCSFSHIFAGGYAAGYYSYKWAE 897
H + + D + R + + +P +P F+HIF GGYAAGYY+Y W +
Sbjct: 560 RWHCLEENEAMQDVDDFELRALVAENMDLPAIPPRYRSSYFAHIFGGGYAAGYYAYLWTQ 619
Query: 898 VLSADAFSAFEDAGLDDIKAVKETGQRFRNTILALGGGKAPLKVFVEFRGREPSPEPLFR 1077
+L+ D + F + G +E G RFR IL+ G + +++ ++RG+ P P+ +
Sbjct: 620 MLADDGYQWFVEQG----GLTRENGLRFREAILSRGNSEDLERLYRQWRGKAPKIMPMLQ 675
Query: 1078 HNG 1086
H G
Sbjct: 676 HRG 678
>sp|Q54DD2|THOPL_DICDI Thimet-like oligopeptidase OS=Dictyostelium discoideum
GN=DDB_G0292362 PE=3 SV=1
Length = 673
Score = 144 bits (361), Expect = 2e-033
Identities = 84/235 (35%), Positives = 129/235 (54%), Gaps = 9/235 (3%)
Frame = +1
Query: 361 PVAQMVCNQTPPVGDKPSLMTFREVETVFHEFGHALQHMLTKEDEGLVAGIRNIEWDAVE 540
PVA M+CN T P PSL+T EV T FHEFGH + +M TK + +G ++E D VE
Sbjct: 436 PVAAMLCNFTKPTPTTPSLLTHDEVVTFFHEFGHVMHNMSTKVHYSMFSG-TSVERDFVE 494
Query: 541 LPSQFMENWCYHRDTLMS-IAKHYQT-GESLPENVYKKLLAARTFRAGSLSLRQLKFATV 714
PSQ E WC+++D L++ ++ HY+ + LP ++ ++++AA+ LRQ++ A
Sbjct: 495 CPSQLFEFWCWNKDVLVNKLSGHYKDHSKKLPTDLVERMIAAKNLNVAIFYLRQIQLALF 554
Query: 715 DLELHTKYVPGGTESIYDVDQRVSMKTQVIPPLPEDRFLCSFSHIFAGGYAAGYYSYKWA 894
D +H+ P + D+ R++ + P CSF H+ GGY A YYSY ++
Sbjct: 555 DNAIHSGN-PANFTNTADLYHRIATDVALNPNQKGTNPGCSFGHLL-GGYDAQYYSYLYS 612
Query: 895 EVLSADAFSAFEDAGLDDIKAVKETGQRFRNTILALGGGKAPLKVFVEFRGREPS 1059
E SA F F+ G+ + KE G R RN +LA+GG + + F G +P+
Sbjct: 613 ECFSASIFEIFDKHGVMN----KELGARLRNQVLAVGGSQPSSETIENFLGSKPN 663
>sp|P42675|NEUL_RABIT Neurolysin, mitochondrial OS=Oryctolagus cuniculus GN=NLN
PE=1 SV=1
Length = 704
Score = 143 bits (358), Expect = 4e-033
Identities = 85/237 (35%), Positives = 126/237 (53%), Gaps = 15/237 (6%)
Frame = +1
Query: 358 LPVAQMVCNQTPPVGDKPSLMTFREVETVFHEFGHALQHMLTKEDEGLVAGIRNIEWDAV 537
L VA +V N + PV +PSL+ EV T FHEFGH + + + D +G N+E D V
Sbjct: 467 LSVAALVVNFSQPVAGRPSLLRHDEVRTYFHEFGHVMHQICAQTDFARFSG-TNVETDFV 525
Query: 538 ELPSQFMENWCYHRDTLMSIAKHYQTGESLPENVYKKLLAARTFRAGSLSLRQLKFATVD 717
E+PSQ +ENW + D+L ++KHY+ G + +++ +KL+A+R G L+LRQ+ + VD
Sbjct: 526 EVPSQMLENWVWDIDSLRRLSKHYKDGNPIADDLLEKLVASRLVNTGLLTLRQIVLSKVD 585
Query: 718 LELHTKYVPGGTESIYDVDQRVSMKTQV--IPPLPEDRFLCSFSHIFAGGYAAGYYSYKW 891
LHT S+ + T + + P +F H+ AGGY YY Y W
Sbjct: 586 QSLHT------NSSLDAASEYARYCTDILGVAATPGTNMPATFGHL-AGGYDGQYYGYLW 638
Query: 892 AEVLSADAF-SAFEDAGLDDIKAVKETGQRFRNTILALGGGKAPLKVFVEFRGREPS 1059
+EV S D F S F+ G+ + E G ++RN IL GG + + F REP+
Sbjct: 639 SEVFSMDMFYSCFKKEGIMN----PEVGMKYRNLILRPGGSLDGMDMLQNFLQREPN 691
>sp|Q1JPJ8|THOP1_BOVIN Thimet oligopeptidase OS=Bos taurus GN=THOP1 PE=2 SV=3
Length = 687
Score = 142 bits (357), Expect = 6e-033
Identities = 81/226 (35%), Positives = 121/226 (53%), Gaps = 7/226 (3%)
Frame = +1
Query: 268 LVLQKREAVLGWMKFFSRSRVMAQKGSSVRLPVAQMVCNQTPPVGDKPSLMTFREVETVF 447
L L RE G F +K S ++ +A MV N T P D PSL+ EVET F
Sbjct: 413 LDLYPREGKYGHAACFGLQPGCLRKDGSRQIAIAAMVANFTKPTPDAPSLLQHDEVETYF 472
Query: 448 HEFGHALQHMLTKEDEGLVAGIRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYQTGESL 627
HEFGH + + ++ + + +G ++E D VE PSQ +ENW + + L+ +++HY+TG S+
Sbjct: 473 HEFGHVMHQLCSQAEFAMFSG-THVERDFVEAPSQMLENWVWEAEPLLRMSQHYRTGSSI 531
Query: 628 PENVYKKLLAARTFRAGSLSLRQLKFATVDLELHTKYVPGGTESIYDVDQRVSMKTQVIP 807
P+ + KL+ +R G +LRQ+ A VD LHT+ + R+ + +P
Sbjct: 532 PQELLDKLIKSRQANTGLFNLRQIVLAKVDQALHTQTAADPAKEY----ARLCQEILGVP 587
Query: 808 PLPEDRFLCSFSHIFAGGYAAGYYSYKWAEVLSADAF-SAFEDAGL 942
P +F H+ AGGY A YY Y W+EV SAD F + F+ G+
Sbjct: 588 ATPGTNMPATFGHL-AGGYDAQYYGYLWSEVYSADMFHTRFKQEGV 632
>sp|Q8C1A5|THOP1_MOUSE Thimet oligopeptidase OS=Mus musculus GN=Thop1 PE=1 SV=1
Length = 687
Score = 142 bits (357), Expect = 6e-033
Identities = 83/226 (36%), Positives = 122/226 (53%), Gaps = 7/226 (3%)
Frame = +1
Query: 268 LVLQKREAVLGWMKFFSRSRVMAQKGSSVRLPVAQMVCNQTPPVGDKPSLMTFREVETVF 447
L L RE G F ++ S +L VA MV N T P D PSL+ EVET F
Sbjct: 413 LDLYPREGKYGHAACFGLQPGCLRQDGSRQLAVAAMVANFTKPTPDAPSLLQHDEVETYF 472
Query: 448 HEFGHALQHMLTKEDEGLVAGIRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYQTGESL 627
HEFGH + + ++ + + +G ++E D VE PSQ +ENW + ++ LM +++HY+TG
Sbjct: 473 HEFGHVMHQLCSQAEFAMFSG-THVERDFVEAPSQMLENWVWEKEPLMRMSQHYRTGSEA 531
Query: 628 PENVYKKLLAARTFRAGSLSLRQLKFATVDLELHTKYVPGGTESIYDVDQRVSMKTQVIP 807
P+++ +KL+ +R AG +LRQ+ A VD LHT+ E R+ + +P
Sbjct: 532 PQDLLEKLIKSRQANAGLFNLRQIVLAKVDQVLHTQTDADPAEEY----ARLCQEILGVP 587
Query: 808 PLPEDRFLCSFSHIFAGGYAAGYYSYKWAEVLSADAF-SAFEDAGL 942
P +F H+ AGGY A YY Y W+EV S D F + F+ G+
Sbjct: 588 ATPGTNMPATFGHL-AGGYDAQYYGYLWSEVYSMDMFHTRFKQEGV 632
>sp|P47788|THOP1_PIG Thimet oligopeptidase OS=Sus scrofa GN=THOP1 PE=2 SV=2
Length = 687
Score = 142 bits (357), Expect = 6e-033
Identities = 80/226 (35%), Positives = 122/226 (53%), Gaps = 7/226 (3%)
Frame = +1
Query: 268 LVLQKREAVLGWMKFFSRSRVMAQKGSSVRLPVAQMVCNQTPPVGDKPSLMTFREVETVF 447
L L RE G F ++ S ++ +A MV N T P D PSL+ EVET F
Sbjct: 413 LDLYPREGKYGHAACFGLQPGCLRQDGSRQIAIAAMVANFTKPTPDAPSLLQHDEVETYF 472
Query: 448 HEFGHALQHMLTKEDEGLVAGIRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYQTGESL 627
HEFGH + + ++ + + +G ++E D VE PSQ +ENW + + L+ +++HY+TG ++
Sbjct: 473 HEFGHVMHQLCSQAEFAMFSG-THVERDFVEAPSQMLENWVWEAEPLLRMSQHYRTGSAI 531
Query: 628 PENVYKKLLAARTFRAGSLSLRQLKFATVDLELHTKYVPGGTESIYDVDQRVSMKTQVIP 807
P+ + +KL+ +R G +LRQ+ A VD LHT+ E R+ + +P
Sbjct: 532 PQELLEKLIKSRQANTGLFNLRQIVLAKVDQALHTQTAADPAEEY----ARLCQEILGVP 587
Query: 808 PLPEDRFLCSFSHIFAGGYAAGYYSYKWAEVLSADAF-SAFEDAGL 942
P +F H+ AGGY A YY Y W+EV SAD F + F+ G+
Sbjct: 588 ATPGTNMPATFGHL-AGGYDAQYYGYLWSEVYSADMFHTRFKQEGI 632
>sp|P27236|DCP_SALTY Peptidyl-dipeptidase dcp OS=Salmonella typhimurium GN=dcp
PE=1 SV=1
Length = 680
Score = 142 bits (356), Expect = 7e-033
Identities = 80/243 (32%), Positives = 124/243 (51%), Gaps = 6/243 (2%)
Frame = +1
Query: 361 PVAQMVCNQTPPVGDKPSLMTFREVETVFHEFGHALQHMLTKEDEGLVAGIRNIEWDAVE 540
PV VCN PV +P+L+ + +V T+FHEFGH L + + ++G N D VE
Sbjct: 440 PVIYNVCNYQKPVDGQPALLLWDDVITLFHEFGHTLHGLFAVQRYATLSG-TNTPRDFVE 498
Query: 541 LPSQFMENWCYHRDTLMSIAKHYQTGESLPENVYKKLLAARTFRAGSLSLRQLKFATVDL 720
PSQ E+W H A+H +GE +P ++ +++ A F G L A +D+
Sbjct: 499 FPSQINEHWASHPRVFERYARHVDSGEKMPADLQERMRKASLFNKGYDMTELLGAALLDM 558
Query: 721 ELHTKYVPGGTESIYDVDQRVSMKTQVIPPLPEDRFLCS-FSHIFAGGYAAGYYSYKWAE 897
H +S+ + +Q+ + P R+ S F+HIF GGYAAGYY+Y W +
Sbjct: 559 RWHMLEESVAEQSVAEFEQQALAAEHLDLPAVPPRYRSSYFAHIFGGGYAAGYYAYLWTQ 618
Query: 898 VLSADAFSAFEDAGLDDIKAVKETGQRFRNTILALGGGKAPLKVFVEFRGREPSPEPLFR 1077
+L+ D + F + G +E GQRFR+ ILA G ++ +RG EP +P+ +
Sbjct: 619 MLADDGYQWFVEQG----GLTRENGQRFRDAILARGNSTDLETLYSAWRGHEPHIDPMLQ 674
Query: 1078 HNG 1086
+ G
Sbjct: 675 YRG 677
>sp|P24155|THOP1_RAT Thimet oligopeptidase OS=Rattus norvegicus GN=Thop1 PE=1
SV=4
Length = 687
Score = 141 bits (355), Expect = 1e-032
Identities = 83/226 (36%), Positives = 122/226 (53%), Gaps = 7/226 (3%)
Frame = +1
Query: 268 LVLQKREAVLGWMKFFSRSRVMAQKGSSVRLPVAQMVCNQTPPVGDKPSLMTFREVETVF 447
L L RE G F ++ S +L +A MV N T P D PSL+ EVET F
Sbjct: 413 LDLYPREGKYGHAACFGLQPGCLRQDGSRQLAIAAMVANFTKPTPDVPSLLQHDEVETYF 472
Query: 448 HEFGHALQHMLTKEDEGLVAGIRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYQTGESL 627
HEFGH + + ++ + + +G ++E D VE PSQ +ENW + ++ LM +++HY+TG
Sbjct: 473 HEFGHVMHQLCSQAEFAMFSG-THVERDFVEAPSQMLENWVWEKEPLMRMSQHYRTGGEA 531
Query: 628 PENVYKKLLAARTFRAGSLSLRQLKFATVDLELHTKYVPGGTESIYDVDQRVSMKTQVIP 807
PE++ +KL+ +R AG +LRQ+ A VD LHT+ E R+ + +P
Sbjct: 532 PEDLLEKLIKSRQANAGLFNLRQIVLAKVDQVLHTQTDVDPAEEY----ARLCQEILGVP 587
Query: 808 PLPEDRFLCSFSHIFAGGYAAGYYSYKWAEVLSADAF-SAFEDAGL 942
P +F H+ AGGY A YY Y W+EV S D F + F+ G+
Sbjct: 588 ATPGTNMPATFGHL-AGGYDAQYYGYLWSEVYSMDMFHTRFKQEGV 632
>sp|P52888|THOP1_HUMAN Thimet oligopeptidase OS=Homo sapiens GN=THOP1 PE=1 SV=2
Length = 689
Score = 139 bits (350), Expect = 4e-032
Identities = 79/226 (34%), Positives = 121/226 (53%), Gaps = 7/226 (3%)
Frame = +1
Query: 268 LVLQKREAVLGWMKFFSRSRVMAQKGSSVRLPVAQMVCNQTPPVGDKPSLMTFREVETVF 447
L L RE G F ++ S ++ +A MV N T P D PSL+ EVET F
Sbjct: 413 LDLYPREGKYGHAACFGLQPGCLRQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYF 472
Query: 448 HEFGHALQHMLTKEDEGLVAGIRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYQTGESL 627
HEFGH + + ++ + + +G ++E D VE PSQ +ENW + ++ L+ +++HY+TG ++
Sbjct: 473 HEFGHVMHQLCSQAEFAMFSG-THVERDFVEAPSQMLENWVWEQEPLLRMSRHYRTGSAV 531
Query: 628 PENVYKKLLAARTFRAGSLSLRQLKFATVDLELHTKYVPGGTESIYDVDQRVSMKTQVIP 807
P + +KL+ +R G +LRQ+ A VD LHT+ E R+ + +P
Sbjct: 532 PRELLEKLIESRQANTGLFNLRQIVLAKVDQALHTQTDADPAEEY----ARLCQEILGVP 587
Query: 808 PLPEDRFLCSFSHIFAGGYAAGYYSYKWAEVLSADAF-SAFEDAGL 942
P +F H+ AGGY A YY Y W+EV S D F + F+ G+
Sbjct: 588 ATPGTNMPATFGHL-AGGYDAQYYGYLWSEVYSMDMFHTRFKQEGV 632
>sp|P25375|PRTD_YEAST Saccharolysin OS=Saccharomyces cerevisiae GN=PRD1 PE=1
SV=1
Length = 712
Score = 138 bits (345), Expect = 1e-031
Identities = 84/269 (31%), Positives = 132/269 (49%), Gaps = 6/269 (2%)
Frame = +1
Query: 274 LQKREAVLGWMKFFSRSRVMAQKGSSVRLPVAQMVCNQTPPVGDKPSLMTFREVETVFHE 453
L R+ G F S ++ PV +VCN + DKPSL+ E+ T FHE
Sbjct: 443 LHPRDGKYGHAANFGLSSSFMIDDTTRSYPVTALVCNFSKSTKDKPSLLKHNEIVTFFHE 502
Query: 454 FGHALQHMLTKEDEGLVAGIRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYQTGESLPE 633
GH + ++ + E G ++ WD VE PSQ +E W ++++ L++++ HY+TGE +PE
Sbjct: 503 LGHGIHDLVGQNKESRFNGPGSVPWDFVEAPSQMLEFWTWNKNELINLSSHYKTGEKIPE 562
Query: 634 NVYKKLLAARTFRAGSLSLRQLKFATVDLELHTKYVPGGTESIYDVDQRVSMKTQVIPPL 813
++ L+ + +LRQL F D+++HT SI D ++ +I
Sbjct: 563 SLINSLIKTKHVNGALFTLRQLHFGLFDMKVHT-CKDLQNLSICDTWNQLRQDISLISNG 621
Query: 814 PE-DRFLCSFSHIFAGGYAAGYYSYKWAEVLSADAFSAFEDAGLDDIKAVKETGQRFRNT 990
+ SF HI + Y+AGYY Y WAEV + D + D + A + G ++R+
Sbjct: 622 GTLSKGYDSFGHIMSDSYSAGYYGYLWAEVFATDMYHT--KFAKDPLNA--KNGIQYRDI 677
Query: 991 ILALGGGKAPLKVFVEFRGREPSPEPLFR 1077
+LA GG EF GREPS + +
Sbjct: 678 VLARGGLYDINDNLKEFLGREPSKDAFLK 706
>sp|Q6CHD6|PMIP_YARLI Mitochondrial intermediate peptidase OS=Yarrowia
lipolytica GN=OCT1 PE=3 SV=1
Length = 776
Score = 103 bits (255), Expect = 4e-021
Identities = 71/233 (30%), Positives = 112/233 (48%), Gaps = 19/233 (8%)
Frame = +1
Query: 343 GSSVRLPVAQMVCNQTPPVGDKPSLMTFREVETVFHEFGHALQHMLTKEDEGLVAGIRNI 522
G ++P ++C+ T P PSL++++EVET+FHE GHA+ ML + V G R
Sbjct: 526 GKVFQIPTIALICDFTTPHDLYPSLLSYQEVETLFHEMGHAIHSMLGRTSLHNVCGTR-C 584
Query: 523 EWDAVELPSQFMENWCYHRDTLMSIAKHYQTGESLPENVYKKLLAARTFRAGSLSLRQLK 702
D VELPS FMEN+ + ++L A+HY + LP ++ L +++ Q+K
Sbjct: 585 ATDFVELPSVFMENFASNPESLALFARHYSSDSPLPYQQLERHLNEQSYFKDVEQYTQIK 644
Query: 703 FATVDLELH---TKYVPGGTESIYDVDQRVSMKTQVIPPLPEDRFLCSFSHIFAGGYAAG 873
A +D LH K + G + + + + PP P + SF H+F GY A
Sbjct: 645 MAMLDQVLHGNILKSITNGHFNSQKLYDNLEKDRPLFPPSPSS-WHGSFGHLF--GYGAS 701
Query: 874 YYSY----KWAEVLSADAFSAFEDAGLDDIKAVKETGQRFRNTILALGGGKAP 1020
YY Y + A+++ FS ++ G R +N +L GG + P
Sbjct: 702 YYCYLLDRQMADIVWKKLFS--------KNPLSRDAGSRMKNEVLQWGGSRDP 746
>sp|Q6CVF7|PMIP_KLULA Mitochondrial intermediate peptidase OS=Kluyveromyces
lactis GN=OCT1 PE=3 SV=1
Length = 779
Score = 97 bits (241), Expect = 2e-019
Identities = 70/235 (29%), Positives = 109/235 (46%), Gaps = 18/235 (7%)
Frame = +1
Query: 343 GSSVRLPVAQMVC-------NQTPPVGDKPSLMTFREVETVFHEFGHALQHMLTKEDEGL 501
G +LPV +VC N + L+ E+ET+FHE GHA+ ML +
Sbjct: 523 GQKFQLPVISLVCDFRWVEVNMGDGKHQQMCLLQLNEIETLFHEMGHAMHSMLGRTQLQN 582
Query: 502 VAGIRNIEWDAVELPSQFMENWCYHRDTLMSIAKHYQTGESLPENVYKKLLAARTFRAGS 681
V+G R D VELPS ME++ L SI+ HY+TG+SL V K F
Sbjct: 583 VSGTR-CATDFVELPSILMEHFARDTRVLSSISSHYKTGKSLDVEVLKNHQLENQFLQNC 641
Query: 682 LSLRQLKFATVDLELHT-KYVPGGTESIYDVDQRVSMKTQVIPPLPEDRFLCSFSHIFAG 858
+ Q+K + +D ELH + G+ + + R+ + V+P + + F H+F
Sbjct: 642 ETFSQIKMSFLDQELHNLDHTTDGSIDVIAIYHRLERRLAVLPD-DQSNWCGKFGHLF-- 698
Query: 859 GYAAGYYSYKWAEVLSADAFS-AFEDAGLDDIKAVKETGQRFRNTILALGGGKAP 1020
GY A YYSY + +++ + FE + + G +F+ +L GG + P
Sbjct: 699 GYGASYYSYLFDRAIASKIWDHLFEQDPFN-----RTNGTKFKEGLLQWGGSRDP 748
>sp|Q753X4|PMIP_ASHGO Mitochondrial intermediate peptidase OS=Ashbya gossypii
GN=OCT1 PE=3 SV=1
Length = 776
Score = 86 bits (211), Expect = 5e-016
Identities = 61/192 (31%), Positives = 95/192 (49%), Gaps = 10/192 (5%)
Frame = +1
Query: 343 GSSVRLPVAQMVCN-QTPPVGDKPS--LMTFREVETVFHEFGHALQHMLTKEDEGLVAGI 513
GS ++PV ++CN + G S L+ +VET+FHE GHAL ML + ++G
Sbjct: 529 GSRFQMPVISLICNFRATRHGKNKSLCLLELSDVETLFHEMGHALHSMLGRTQLQNLSGT 588
Query: 514 RNIEWDAVELPSQFMENWCYHRDTLMSIAKHYQTGESLPENVYKKLLAARTFRAGSLSLR 693
R + D VELPS ME++ R L+ I+ +Y TGE +PE + F + +
Sbjct: 589 RCVT-DFVELPSILMEHFAKDRRVLLRISSNYATGEPIPEELLSAFQEQNNFLKNTETFS 647
Query: 694 QLKFATVDLELHTKYVPGGTESIYDVDQRVSMKTQVIPPLPEDRFLCSFSHIFAGGYAAG 873
Q+K + +D LH+ ++Y +R M+ V + + F H+F GY A
Sbjct: 648 QIKMSMLDQRLHSITDQDDIIAVYHGLER-EMEVLVD---DQTNWCGRFGHLF--GYGAS 701
Query: 874 YYSYKWAEVLSA 909
YYSY ++A
Sbjct: 702 YYSYLMDRAIAA 713
>sp|Q5RF14|MIPEP_PONAB Mitochondrial intermediate peptidase OS=Pongo abelii
GN=MIPEP PE=2 SV=1
Length = 713
Score = 86 bits (210), Expect = 6e-016
Identities = 57/185 (30%), Positives = 92/185 (49%), Gaps = 5/185 (2%)
Frame = +1
Query: 355 RLPVAQMVCNQTPPVGDKPSLMTFREVETVFHEFGHALQHMLTKEDEGLVAGIRNIEWDA 534
+LPV ++ N P+L+T +E +FHE GHA+ ML + V G R D
Sbjct: 464 QLPVVVLMLNLPRSSRSSPTLLTPGMMENLFHEMGHAMHSMLGRTRYQHVTGTR-CPTDF 522
Query: 535 VELPSQFMENWCYHRDTLMSIAKHYQTGESLPENVYKKLLAARTFRAGSLSLRQLKFATV 714
E+PS ME + + A+HYQTG+ LP+N+ +L ++ A + Q+ +AT+
Sbjct: 523 AEVPSILMEYFANDYRVVNQFARHYQTGQPLPKNMVSRLCESKKVCAAADMQLQVFYATL 582
Query: 715 DLELHTKYVPGGTESIYDVDQRVSMKTQVIPPLPEDRFLCSFSHIFAGGYAAGYYSYKWA 894
D H K+ S D+ + K +P +P+ + FSH+ GY A YYSY +
Sbjct: 583 DQIYHGKHPL--RNSTTDILKETQEKFYGLPYVPDTAWQLRFSHLV--GYGAKYYSYLMS 638
Query: 895 EVLSA 909
+++
Sbjct: 639 RAVAS 643
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,745,191,639
Number of Sequences: 518415
Number of Extensions: 102745191639
Number of Successful Extensions: 656160410
Number of sequences better than 0.0: 0
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