BLASTX 7.6.2
Query= UN24998 /QuerySize=1384
(1383 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q54JH6|CMT1_DICDI DNA (cytosine-5)-methyltransferase OS=Dicty... 159 4e-038
sp|O14717|TRDMT_HUMAN tRNA (cytosine-5-)-methyltransferase OS=Ho... 150 2e-035
sp|Q7YS61|TRDMT_BOVIN tRNA (cytosine-5-)-methyltransferase OS=Bo... 148 2e-034
sp|Q4G073|TRDMT_RAT tRNA (cytosine-5-)-methyltransferase OS=Ratt... 147 2e-034
sp|O55055|TRDMT_MOUSE tRNA (cytosine-5-)-methyltransferase OS=Mu... 146 5e-034
sp|P40999|PMT1M_SCHPO DNA methyltransferase homolog pmt1 OS=Schi... 132 7e-030
sp|P19888|MTBA_BACAR Modification methylase BanI OS=Bacillus ane... 66 5e-010
sp|P25263|MTC1_HERAU Modification methylase HgiCI OS=Herpetosiph... 62 7e-009
sp|P34879|MTS2_SHISO Modification methylase SsoII OS=Shigella so... 60 4e-008
>sp|Q54JH6|CMT1_DICDI DNA (cytosine-5)-methyltransferase OS=Dictyostelium
discoideum GN=dnmA PE=1 SV=1
Length = 379
Score = 159 bits (402), Expect = 4e-038
Identities = 94/234 (40%), Positives = 135/234 (57%), Gaps = 19/234 (8%)
Frame = +3
Query: 54 RVLEFYSGIGGMRYSLMASGVVAEVVEAFEINDVANDVYQHNFGHRPHQGNIQSLTAAYL 233
RVLEFYSGIGGM Y L SGV +V+++F+IN AN Y++ F Q +I+S + L
Sbjct: 5 RVLEFYSGIGGMHYGLQESGVDFQVIQSFDINTNANLNYKYTFNEDSSQKSIESYSVEEL 64
Query: 234 DRYNADAWLLSLPCQPYTRQGLQKHSGDARASSFLKILELIPHTSTPPRMLFVENVVGFE 413
+ + A+AWL+S PCQP+TR GLQK D R +SF +L+++ PP + +ENV GF
Sbjct: 65 EGFKANAWLMSPPCQPFTRLGLQKDDQDNRTNSFFHLLDVLTKIKDPPTYILIENVFGFA 124
Query: 414 ---TSDTHMEMIDTLKKSDYVTQEFILSPLQFGVPYSRPRYFCLAKRK-PLSF---QSQH 572
+S+T ++DTL K +Y QEF LSP QFG+ R RYFC+AKR L+F Q +H
Sbjct: 125 KKGSSNTRDHLLDTLIKMNYSFQEFHLSPQQFGLANQRLRYFCIAKRNGKLNFKKEQDKH 184
Query: 573 N----NNKLLWSPGPLCGRDDQVEFDNCQ-----GEQGSENLLQSCEPVEKFLD 707
N NKL + ++Q ++DN + L+ C+ + + D
Sbjct: 185 NEKVDENKLNNNSN---NNNEQNKYDNLKILDHIPGYDFHTTLEECDEISNYFD 235
Score = 80 bits (197), Expect = 2e-014
Identities = 47/133 (35%), Positives = 75/133 (56%), Gaps = 13/133 (9%)
Frame = +1
Query: 787 DDTDSDSVHRYLVPLSLIERWGNAMDIVYPDSKRCCCFTKSYYRYVKGTGSLLA---TVQ 957
D TD + +Y VP +L+ G DI DSK C TKSY ++++GTGS++ +
Sbjct: 237 DLTDDELYEKYKVPHNLLLSKGMLFDIKQKDSKTSNCVTKSYGKFIEGTGSIIQMDNNFK 296
Query: 958 PKIKGKETCLKEQRLRYFTPREMVFGFYFD*VANFHSFPEDFEFPEQISLRQRYAMLGNS 1137
I ++ L +LRYF+P+E + H FPE+F+F +++ Q Y ++GNS
Sbjct: 297 ADINDNKS-LIPLKLRYFSPKE---------ITRLHGFPEEFKFSPKLTTIQCYRLIGNS 346
Query: 1138 LSVAVVAPLLRYL 1176
L+V +V+ LL+ L
Sbjct: 347 LNVKIVSELLKVL 359
>sp|O14717|TRDMT_HUMAN tRNA (cytosine-5-)-methyltransferase OS=Homo sapiens
GN=TRDMT1 PE=1 SV=1
Length = 391
Score = 150 bits (378), Expect = 2e-035
Identities = 79/177 (44%), Positives = 112/177 (63%), Gaps = 3/177 (1%)
Frame = +3
Query: 45 KPWRVLEFYSGIGGMRYSLMASGVVAEVVEAFEINDVANDVYQHNFGHRPHQG-NIQSLT 221
+P RVLE YSG+GGM ++L S + A+VV A ++N VAN+VY++NF H I+ +T
Sbjct: 2 EPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVANEVYKYNFPHTQLLAKTIEGIT 61
Query: 222 AAYLDRYNADAWLLSLPCQPYTRQGLQKHSGDARASSFLKILELIPHTSTPPRMLFVENV 401
DR + D L+S PCQP+TR G Q D+R +SFL IL+++P P+ + +ENV
Sbjct: 62 LEEFDRLSFDMILMSPPCQPFTRIGRQGDMTDSRTNSFLHILDILPRLQKLPKYILLENV 121
Query: 402 VGFETSDTHMEMIDTLKKSDYVTQEFILSPLQFGVPYSRPRYFCLAK--RKPLSFQS 566
GFE S T +I T++ + QEF+LSP G+P SR RYF +AK +PL FQ+
Sbjct: 122 KGFEVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSRLRYFLIAKLQSEPLPFQA 178
Score = 90 bits (221), Expect = 4e-017
Identities = 53/136 (38%), Positives = 82/136 (60%), Gaps = 9/136 (6%)
Frame = +1
Query: 787 DDTDSDSVHRYLVPLSLIERWGNAMDIVYPDSKRCCCFTKSYYRYVKGTGSLLAT----- 951
DDTD V++YL+P + R+ +DIV P +R CFTK Y Y++GTGS+L T
Sbjct: 259 DDTD---VNQYLLPPKSLLRYALLLDIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQ 315
Query: 952 VQPKIKGKETCLKEQRLRYFTPREMVFGFYFD*VANFHSFPEDFEFPEQISLRQRYAMLG 1131
V+ K +E+++ ++ + F +AN FP +F FPE+I+++QRY +LG
Sbjct: 316 VENIYKSLTNLSQEEQITKLLILKLRY-FTPKEIANLLGFPPEFGFPEKITVKQRYRLLG 374
Query: 1132 NSLSVAVVAPLLRYLF 1179
NSL+V VVA L++ L+
Sbjct: 375 NSLNVHVVAKLIKILY 390
>sp|Q7YS61|TRDMT_BOVIN tRNA (cytosine-5-)-methyltransferase OS=Bos taurus
GN=TRDMT1 PE=2 SV=1
Length = 391
Score = 148 bits (371), Expect = 2e-034
Identities = 80/186 (43%), Positives = 111/186 (59%), Gaps = 1/186 (0%)
Frame = +3
Query: 45 KPWRVLEFYSGIGGMRYSLMASGVVAEVVEAFEINDVANDVYQHNFGHRPHQG-NIQSLT 221
+P R LE YSGIGGM +L S + A+VV A ++N VAN+VY++NF H I+ +T
Sbjct: 2 EPLRALELYSGIGGMHQALRESCIPAQVVAAVDVNTVANEVYKYNFPHTQLLAKTIEGIT 61
Query: 222 AAYLDRYNADAWLLSLPCQPYTRQGLQKHSGDARASSFLKILELIPHTSTPPRMLFVENV 401
DR + + L+S PCQP+TR GLQ D R +SFL IL+++P P+ + +ENV
Sbjct: 62 LEEFDRLSFNMILMSPPCQPFTRIGLQGDVTDPRTNSFLHILDILPRLQKLPKYILLENV 121
Query: 402 VGFETSDTHMEMIDTLKKSDYVTQEFILSPLQFGVPYSRPRYFCLAKRKPLSFQSQHNNN 581
GFE S T +I T++ + QEF+LSP G+P SR RYF +AK +P F Q
Sbjct: 122 KGFEMSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSRLRYFLIAKLQPEPFPFQAPGQ 181
Query: 582 KLLWSP 599
L+ P
Sbjct: 182 VLMEFP 187
Score = 88 bits (217), Expect = 1e-016
Identities = 51/135 (37%), Positives = 79/135 (58%), Gaps = 9/135 (6%)
Frame = +1
Query: 787 DDTDSDSVHRYLVPLSLIERWGNAMDIVYPDSKRCCCFTKSYYRYVKGTGSLLAT----- 951
DD D H + +P + R+ +DIV P S+R CFTK Y RY++GTGS+L T
Sbjct: 259 DDIDK---HSFFLPPKSLLRYALLLDIVKPTSRRSMCFTKGYGRYIEGTGSVLQTTEDVQ 315
Query: 952 VQPKIKGKETCLKEQRLRYFTPREMVFGFYFD*VANFHSFPEDFEFPEQISLRQRYAMLG 1131
++ K + +E+++ + ++ F F +AN FP +F FPE +++QRY +LG
Sbjct: 316 IENIYKSLTSLSQEEKIMRLSMLQLRF-FTPKEIANLLGFPPEFGFPEMTTVKQRYRLLG 374
Query: 1132 NSLSVAVVAPLLRYL 1176
NSL+V VVA L++ L
Sbjct: 375 NSLNVHVVAKLIKIL 389
>sp|Q4G073|TRDMT_RAT tRNA (cytosine-5-)-methyltransferase OS=Rattus norvegicus
GN=Trdmt1 PE=2 SV=1
Length = 391
Score = 147 bits (370), Expect = 2e-034
Identities = 79/177 (44%), Positives = 111/177 (62%), Gaps = 3/177 (1%)
Frame = +3
Query: 45 KPWRVLEFYSGIGGMRYSLMASGVVAEVVEAFEINDVANDVYQHNFGHRPHQG-NIQSLT 221
+P RVLE YSGIGGM ++L S V A VV A +++ VAN+VY+HNF H I+ ++
Sbjct: 2 EPLRVLELYSGIGGMHHALRESRVPAHVVAAIDVSTVANEVYKHNFPHTHLLAKTIEGIS 61
Query: 222 AAYLDRYNADAWLLSLPCQPYTRQGLQKHSGDARASSFLKILELIPHTSTPPRMLFVENV 401
D+ + + L+S PCQP+TR GLQ D R +SFL IL+++P P+ + +ENV
Sbjct: 62 LEEFDKLSFNMILMSPPCQPFTRIGLQGDMSDRRTNSFLYILDILPRLQKLPKYILLENV 121
Query: 402 VGFETSDTHMEMIDTLKKSDYVTQEFILSPLQFGVPYSRPRYFCLAK--RKPLSFQS 566
GFE S T +I T++ + QEF+LSP G+P SR RYF +AK +PL FQ+
Sbjct: 122 KGFEVSSTRGLLIQTMEACGFQYQEFLLSPSSLGIPNSRLRYFLIAKLQSEPLCFQA 178
Score = 82 bits (201), Expect = 8e-015
Identities = 49/132 (37%), Positives = 77/132 (58%), Gaps = 7/132 (5%)
Frame = +1
Query: 796 DSDSVHRYLVPLSLIERWGNAMDIVYPDSKRCCCFTKSYYRYVKGTGSLLAT-----VQP 960
D D+ +YL+P + R+ +DIV P S+R CFTK Y Y++GTGS+L T ++
Sbjct: 260 DGDTA-QYLLPAKSLLRYALLLDIVKPTSRRSMCFTKGYGSYIEGTGSVLQTAEDVQIEN 318
Query: 961 KIKGKETCLKEQRLRYFTPREMVFGFYFD*VANFHSFPEDFEFPEQISLRQRYAMLGNSL 1140
K E+++ + ++ + F +AN FP +F FPE+ +++QRY +LGNSL
Sbjct: 319 IYKSLPDLPPEEKIAKLSMLKLRY-FTPKEIANLLGFPPEFGFPEKTTVKQRYRLLGNSL 377
Query: 1141 SVAVVAPLLRYL 1176
+V VV+ LL L
Sbjct: 378 NVHVVSKLLTVL 389
>sp|O55055|TRDMT_MOUSE tRNA (cytosine-5-)-methyltransferase OS=Mus musculus
GN=Trdmt1 PE=2 SV=2
Length = 415
Score = 146 bits (367), Expect = 5e-034
Identities = 78/177 (44%), Positives = 110/177 (62%), Gaps = 3/177 (1%)
Frame = +3
Query: 45 KPWRVLEFYSGIGGMRYSLMASGVVAEVVEAFEINDVANDVYQHNFGH-RPHQGNIQSLT 221
+P RVLE YSGIGGM ++L S + A VV A ++N VAN+VY+HNF H I+ ++
Sbjct: 2 EPLRVLELYSGIGGMHHALRESHIPAHVVAAIDVNTVANEVYKHNFPHTHLLSKTIEGIS 61
Query: 222 AAYLDRYNADAWLLSLPCQPYTRQGLQKHSGDARASSFLKILELIPHTSTPPRMLFVENV 401
D+ + + L+S PCQP+TR GLQ D R +SFL IL+++P P+ + +ENV
Sbjct: 62 LEDFDKLSFNMILMSPPCQPFTRIGLQGDMTDPRTTSFLYILDILPRLQKLPKYILLENV 121
Query: 402 VGFETSDTHMEMIDTLKKSDYVTQEFILSPLQFGVPYSRPRYFCLAK--RKPLSFQS 566
GFE S T +I T++ + QEF+LSP G+P SR RYF +AK +P FQ+
Sbjct: 122 KGFEVSSTRGLLIQTIEACGFQYQEFLLSPSSLGIPNSRLRYFLIAKLQSEPFPFQA 178
Score = 87 bits (213), Expect = 3e-016
Identities = 52/135 (38%), Positives = 79/135 (58%), Gaps = 9/135 (6%)
Frame = +1
Query: 787 DDTDSDSVHRYLVPLSLIERWGNAMDIVYPDSKRCCCFTKSYYRYVKGTGSLL-----AT 951
+D D+D YL+P L+ R+ +DIV P S+R CFTK Y Y++GTGS+L A
Sbjct: 259 EDGDTD---EYLLPPKLLLRYALLLDIVKPTSRRSMCFTKGYGSYIEGTGSVLQAAEDAQ 315
Query: 952 VQPKIKGKETCLKEQRLRYFTPREMVFGFYFD*VANFHSFPEDFEFPEQISLRQRYAMLG 1131
++ K E+++ + ++ + F +AN FP +F FPE+ +++QRY +LG
Sbjct: 316 IENIYKSLPDLPPEEKIAKLSMLKLRY-FTPKEIANLQGFPPEFGFPEKTTVKQRYRLLG 374
Query: 1132 NSLSVAVVAPLLRYL 1176
NSL+V VVA LL L
Sbjct: 375 NSLNVHVVAKLLTVL 389
>sp|P40999|PMT1M_SCHPO DNA methyltransferase homolog pmt1 OS=Schizosaccharomyces
pombe GN=pmt1 PE=1 SV=1
Length = 330
Score = 132 bits (331), Expect = 7e-030
Identities = 70/169 (41%), Positives = 98/169 (57%)
Frame = +3
Query: 36 IEEKPWRVLEFYSGIGGMRYSLMASGVVAEVVEAFEINDVANDVYQHNFGHRPHQGNIQS 215
+ K RVLE YSGIGGM Y+L + + A++V A +IN AN++Y N G +I +
Sbjct: 2 LSTKRLRVLELYSGIGGMHYALNLANIPADIVCAIDINPQANEIYNLNHGKLAKHMDIST 61
Query: 216 LTAAYLDRYNADAWLLSLPCQPYTRQGLQKHSGDARASSFLKILELIPHTSTPPRMLFVE 395
LTA D ++ W +S CQP+TR G +K D R+ +FL IL ++PH + P + +E
Sbjct: 62 LTAKDFDAFDCKLWTMSPSCQPFTRIGNRKDILDPRSQAFLNILNVLPHVNNLPEYILIE 121
Query: 396 NVVGFETSDTHMEMIDTLKKSDYVTQEFILSPLQFGVPYSRPRYFCLAK 542
NV GFE S E L+ Y E ILSP QF +P SR R++ LA+
Sbjct: 122 NVQGFEESKAAEECRKVLRNCGYNLIEGILSPNQFNIPNSRSRWYGLAR 170
Score = 76 bits (186), Expect = 5e-013
Identities = 46/123 (37%), Positives = 67/123 (54%), Gaps = 12/123 (9%)
Frame = +1
Query: 817 YLVPLSLIERWGNAMDIVYPDSKRCCCFTKSYYRYVKGTGSLLATVQPKIKGK--ETCLK 990
Y+V S++ +WG+ DIV PDS CCCFT+ Y V+G GS+L + + E
Sbjct: 211 YMVLESVLNKWGHQFDIVKPDSSSCCCFTRGYTHLVQGAGSILQMSDHENTHEQFERNRM 270
Query: 991 EQRLRYFTPREMVFGFYFD*VANFHSFPEDFEFPE-QISLRQRYAMLGNSLSVAVVAPLL 1167
+LRYFT RE VA FPE E+ + ++ + Y +LGNS++V VV+ L+
Sbjct: 271 ALQLRYFTARE---------VARLMGFPESLEWSKSNVTEKCMYRLLGNSINVKVVSYLI 321
Query: 1168 RYL 1176
L
Sbjct: 322 SLL 324
>sp|P19888|MTBA_BACAR Modification methylase BanI OS=Bacillus aneurinolyticus
GN=banIM PE=1 SV=1
Length = 428
Score = 66 bits (160), Expect = 5e-010
Identities = 49/168 (29%), Positives = 80/168 (47%), Gaps = 14/168 (8%)
Frame = +3
Query: 54 RVLEFYSGIGGMRYSLMASG----VVAEVVEAFEINDVANDVYQHNFGHRPHQGNIQSLT 221
+ ++ ++GIGG+R + + E V + EI+ A + Y NF P QG+I +T
Sbjct: 4 KFVDLFAGIGGIRIGFERAAKRFELETECVLSSEIDKKACETYALNFKEEP-QGDIHEIT 62
Query: 222 AAYLDRYNADAWLLSLPCQPYTRQGLQKHSGDARASSFLKILELIPHTSTPPRMLFVENV 401
+ D L PCQP++ G Q+ GD R + F ++ ++ P+ +ENV
Sbjct: 63 SF----PEFDFLLAGFPCQPFSYAGKQQGFGDTRGTLFFEVERVL--RDNRPKAFLLENV 116
Query: 402 VGFETSD---THMEMIDTLKKSDYVTQEFILSPLQFGVPYSRPRYFCL 536
G T D T +I L++ Y +L+ FGVP +R R + L
Sbjct: 117 RGLVTHDKGRTLKTIISKLEELGYGVSYLLLNSSTFGVPQNRVRIYIL 164
>sp|P25263|MTC1_HERAU Modification methylase HgiCI OS=Herpetosiphon aurantiacus
GN=hgiCIM PE=3 SV=2
Length = 420
Score = 62 bits (150), Expect = 7e-009
Identities = 50/166 (30%), Positives = 79/166 (47%), Gaps = 15/166 (9%)
Frame = +3
Query: 54 RVLEFYSGIGGMR----YSLMASGVVAEVVEAFEINDVANDVYQHNFGHRPHQGNIQSLT 221
+ ++ ++GIGGMR ++ G+ V + EI+ A Y NF H QG+I +
Sbjct: 3 KFIDLFAGIGGMRLGFEQAMHELGIETACVLSSEIDKHAQTTYAMNF-HEQSQGDITQIQ 61
Query: 222 AAYLDRYNADAWLLSLPCQPYTRQGLQKHSGDARASSFLKILELIPHTSTPPRMLFVENV 401
D + D L PCQP++ G QK GD R + F +I ++ + P+ +ENV
Sbjct: 62 ----DFPSFDFLLAGFPCQPFSYAGKQKGFGDTRGTLFFEIERIL--KAYRPKGFLLENV 115
Query: 402 VGFETSD---THMEMIDTLKKSDYVTQEFILSPLQFGVPYSRPRYF 530
G T D T ++ L + +Y IL+ F VP +R R +
Sbjct: 116 RGLTTHDKGRTFKTILQKLHELNYGVY-LILNSSNFQVPQNRLRVY 160
>sp|P34879|MTS2_SHISO Modification methylase SsoII OS=Shigella sonnei GN=ssoIIM
PE=3 SV=1
Length = 379
Score = 60 bits (143), Expect = 4e-008
Identities = 46/179 (25%), Positives = 82/179 (45%), Gaps = 5/179 (2%)
Frame = +3
Query: 39 EEKPWRVLEFYSGIGGMRYSLMASGVVAEVVEAFEINDVANDVYQHNFGHRPHQGNIQSL 218
E +R+++ ++GIGG R + V VV + E + A Y N+G P G+I +
Sbjct: 68 ENGRYRMIDLFAGIGGTRLGFHQTNAV-NVVFSSEWDKFAQKTYHANYGDFP-DGDITKI 125
Query: 219 TAAYLDRYNADAWLLSLPCQPYTRQGLQKHSGDARASSFLKILELIPHTSTPPRML-FVE 395
D + + + PC +++ GL+K D R + F I +I +L V+
Sbjct: 126 DEK--DIPDHEILVGGFPCVAFSQAGLKKGFNDTRGTLFFDIARIIKEKKPHAFLLENVK 183
Query: 396 NVVGFETSDTHMEMIDTLKKSDYVTQEFILSPLQFGVPYSRPRYFCLAKRKPLSFQSQH 572
N++G + T + +TL++ +Y I + FGVP +R R + + K +H
Sbjct: 184 NLLGHDKGRTFSIIKNTLEELNYTVYYNIFAAKDFGVPQNRERIYIVGFNKEKVRNHEH 242
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 103,271,942,972
Number of Sequences: 518415
Number of Extensions: 103271942972
Number of Successful Extensions: 661759033
Number of sequences better than 0.0: 0
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