BLASTX 7.6.2
Query= UN25231 /QuerySize=917
(916 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q0WTY4|VPS2B_ARATH Vacuolar protein sorting-associated protei... 391 5e-108
sp|Q941D5|VPS2C_ARATH Vacuolar protein sorting-associated protei... 279 3e-074
sp|Q9SKI2|VPS2A_ARATH Vacuolar protein sorting-associated protei... 169 2e-041
sp|Q54DB1|CM2A2_DICDI Charged multivesicular body protein 2a hom... 151 6e-036
sp|Q9DB34|CHM2A_MOUSE Charged multivesicular body protein 2a OS=... 151 1e-035
sp|Q6DFS6|CHM2A_XENTR Charged multivesicular body protein 2a OS=... 149 2e-035
sp|Q7ZW25|CHM2A_DANRE Charged multivesicular body protein 2a OS=... 149 4e-035
sp|O43633|CHM2A_HUMAN Charged multivesicular body protein 2a OS=... 149 4e-035
sp|Q6IP52|CHM2A_XENLA Charged multivesicular body protein 2a OS=... 149 4e-035
sp|Q6NXD2|CHM2B_DANRE Charged multivesicular body protein 2b OS=... 147 1e-034
sp|Q5F3A2|CHM2B_CHICK Charged multivesicular body protein 2b OS=... 144 1e-033
sp|Q7SYR0|CH2BA_XENLA Charged multivesicular body protein 2b-A O... 143 2e-033
sp|Q66IV6|CH2BB_XENLA Charged multivesicular body protein 2b-B O... 143 2e-033
sp|Q5ZHN1|CHM2A_CHICK Charged multivesicular body protein 2a OS=... 143 3e-033
sp|Q3SX42|CHM2B_BOVIN Charged multivesicular body protein 2b OS=... 143 3e-033
sp|Q9UQN3|CHM2B_HUMAN Charged multivesicular body protein 2b OS=... 143 3e-033
sp|Q5RAV2|CHM2B_PONAB Charged multivesicular body protein 2b OS=... 143 3e-033
sp|Q8BJF9|CHM2B_MOUSE Charged multivesicular body protein 2b OS=... 141 6e-033
sp|Q6NVL7|CHM2B_XENTR Charged multivesicular body protein 2b OS=... 141 6e-033
sp|P36108|DID4_YEAST DOA4-independent degradation protein 4 OS=S... 131 7e-030
>sp|Q0WTY4|VPS2B_ARATH Vacuolar protein sorting-associated protein 2 homolog 2
OS=Arabidopsis thaliana GN=VPS2.2 PE=2 SV=2
Length = 222
Score = 391 bits (1003), Expect = 5e-108
Identities = 210/222 (94%), Positives = 217/222 (97%), Gaps = 2/222 (0%)
Frame = +3
Query: 114 MNIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKI 293
MNIF+KKTTPKDALRTSKREM+VATRGIEREI+SLQ+EEKRLVAEIKKTAKTGNEAATKI
Sbjct: 1 MNIFKKKTTPKDALRTSKREMAVATRGIEREITSLQLEEKRLVAEIKKTAKTGNEAATKI 60
Query: 294 LARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTK 473
LARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTK
Sbjct: 61 LARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTK 120
Query: 474 QAKVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSS 653
QAKVIKDFQKQSA LDMTIEMMSE+IDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSS
Sbjct: 121 QAKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSS 180
Query: 654 APKGRIATKTAAPPAST--TSNSSESSEVDGLEKRLASLRRI 773
APKGRIATKTAAPPAST T+ +SESSEVD LEKRLASLRRI
Sbjct: 181 APKGRIATKTAAPPASTAATNKNSESSEVDELEKRLASLRRI 222
>sp|Q941D5|VPS2C_ARATH Vacuolar protein sorting-associated protein 2 homolog 3
OS=Arabidopsis thaliana GN=VPS2.3 PE=2 SV=1
Length = 210
Score = 279 bits (712), Expect = 3e-074
Identities = 140/197 (71%), Positives = 168/197 (85%)
Frame = +3
Query: 114 MNIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKI 293
MNIF KK P++ LR SKREM+ ATRGIE+EI SLQ EEK+LV EIK+TAK+GNE ATKI
Sbjct: 1 MNIFTKKPNPREVLRESKREMTQATRGIEKEIGSLQSEEKKLVLEIKRTAKSGNEGATKI 60
Query: 294 LARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTK 473
LARQL+RLRQQI NLQGSRAQ+RG+ THTQA++A TS+++GM+GATKAM AM+K M P K
Sbjct: 61 LARQLIRLRQQIANLQGSRAQMRGIATHTQAMHAHTSVAAGMQGATKAMAAMSKNMDPAK 120
Query: 474 QAKVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSS 653
QAKV+++FQKQSA +DMT EMMS+SID+ LD DEAE+ETEDLTNQVLDEIG+ +ASQLSS
Sbjct: 121 QAKVMREFQKQSAQMDMTTEMMSDSIDDALDNDEAEDETEDLTNQVLDEIGIDIASQLSS 180
Query: 654 APKGRIATKTAAPPAST 704
APKG+I K A S+
Sbjct: 181 APKGKIGGKKAEDVGSS 197
>sp|Q9SKI2|VPS2A_ARATH Vacuolar protein sorting-associated protein 2 homolog 1
OS=Arabidopsis thaliana GN=VPS2.1 PE=2 SV=2
Length = 225
Score = 169 bits (428), Expect = 2e-041
Identities = 89/222 (40%), Positives = 141/222 (63%), Gaps = 3/222 (1%)
Frame = +3
Query: 117 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 296
+IF K+ TP + LR +KR + + R IERE LQ +EK+L+ EIKKTAK G A K++
Sbjct: 4 SIFGKRKTPAELLRENKRMLDKSIREIERERQGLQTQEKKLINEIKKTAKQGQMGAVKVM 63
Query: 297 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 476
A+ L+R R QI ++Q++GV+ Q L ++ ++ MKG TKAM MN+QM
Sbjct: 64 AKDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLPSL 123
Query: 477 AKVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 656
K++++F++Q+ ++M E+M ++ID+ L+ DE EEETEDL +QVLDEIG+ + +L +A
Sbjct: 124 QKIMQEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELVNA 183
Query: 657 PKGRIATKTAAPPA--STTSNSSESSEVDG-LEKRLASLRRI 773
P G +A A + + + +S +D L+ RL +LR++
Sbjct: 184 PSGAVAVPAAKNKVVQAEATGAEDSGGIDSDLQARLDNLRKM 225
>sp|Q54DB1|CM2A2_DICDI Charged multivesicular body protein 2a homolog 2
OS=Dictyostelium discoideum GN=chmp2a2 PE=3 SV=1
Length = 198
Score = 151 bits (381), Expect = 6e-036
Identities = 73/182 (40%), Positives = 124/182 (68%)
Frame = +3
Query: 114 MNIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKI 293
M +F K+ TPK+ LR ++R ++ + R I+RE +LQ +EK+++ +IKK AK G + KI
Sbjct: 1 MFLFGKQKTPKEVLRENQRNLNKSMREIDRERVALQNQEKKIILDIKKMAKQGQMNSAKI 60
Query: 294 LARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTK 473
+A+ LVR R I + Q++ V+ Q L ++ +++ MKG TKAM+ MN+QM +
Sbjct: 61 MAKDLVRTRYHIQKFYEMKTQLQAVSLRIQTLQSTQAMAEAMKGVTKAMITMNRQMNLPQ 120
Query: 474 QAKVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSS 653
K++ +F++QS +DM EMM++++D+ +++D EE+++++ NQVLDEIG+ +ASQL
Sbjct: 121 FTKIMMEFEQQSDKMDMKEEMMNDTMDQVMEQDGEEEQSQEILNQVLDEIGIDLASQLVD 180
Query: 654 AP 659
AP
Sbjct: 181 AP 182
>sp|Q9DB34|CHM2A_MOUSE Charged multivesicular body protein 2a OS=Mus musculus
GN=Chmp2a PE=1 SV=1
Length = 222
Score = 151 bits (379), Expect = 1e-035
Identities = 78/219 (35%), Positives = 140/219 (63%), Gaps = 3/219 (1%)
Frame = +3
Query: 120 IFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKILA 299
+F ++ TP++ LR ++R ++ A R ++RE L+ +EK+++A+IKK AK G A +I+A
Sbjct: 4 LFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMA 63
Query: 300 RQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQA 479
+ LVR R+ + RA I+ V+ Q L ++ S++ MKG TKAM MN+Q+ +
Sbjct: 64 KDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQ 123
Query: 480 KVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSAP 659
K++ +F++Q+ +DM EMM+++ID+ + +E EEE++ + +QVLDE+G+ + +LS+ P
Sbjct: 124 KIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLP 183
Query: 660 K--GRIATKTAAPPASTTSNSSESSEVDGLEKRLASLRR 770
G ++ A T+++ ++ D LE+RL +LRR
Sbjct: 184 STGGSLSVAAGGKKAEATASALADADAD-LEERLKNLRR 221
>sp|Q6DFS6|CHM2A_XENTR Charged multivesicular body protein 2a OS=Xenopus
tropicalis GN=chmp2a PE=2 SV=1
Length = 220
Score = 149 bits (376), Expect = 2e-035
Identities = 79/217 (36%), Positives = 136/217 (62%), Gaps = 1/217 (0%)
Frame = +3
Query: 120 IFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKILA 299
+F ++ TP++ LR ++R ++ A R ++RE L+ +EK+++A+IKK AK G A KI+A
Sbjct: 4 LFGRRKTPEEMLRQNQRALNKAMREMDRERQKLEQQEKKIIADIKKMAKQGQMDAVKIMA 63
Query: 300 RQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQA 479
+ LVR R+ + RA I+ V+ Q L ++ S++ MKG TKAM MN+Q+ +
Sbjct: 64 KDLVRTRRYVKKFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQIQ 123
Query: 480 KVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSAP 659
K++ +F+KQS +DM EMM+++ID+ + ++ EEE++ + +QVLDE+G+ + +LS+ P
Sbjct: 124 KIMMEFEKQSEIMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLTDELSNLP 183
Query: 660 KGRIATKTAAPPASTTSNSSESSEVDGLEKRLASLRR 770
+ A S + ++ D LE+RL +LRR
Sbjct: 184 STGGSLSVAGAKKGEPSAALADADAD-LEERLNNLRR 219
>sp|Q7ZW25|CHM2A_DANRE Charged multivesicular body protein 2a OS=Danio rerio
GN=chmp2a PE=2 SV=1
Length = 220
Score = 149 bits (374), Expect = 4e-035
Identities = 78/218 (35%), Positives = 139/218 (63%), Gaps = 1/218 (0%)
Frame = +3
Query: 117 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 296
++F ++ TP++ LR ++R ++ A R ++RE L+ +EK+++A+IKK AK G A KI+
Sbjct: 3 SLFGRRKTPEEMLRQNQRALNRAMRDLDRERQRLEQQEKKIIADIKKMAKQGQMDAVKIM 62
Query: 297 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 476
A+ LVR R+ + RA I+ V+ Q L ++ S++ MKG TKAM MN+Q+ +
Sbjct: 63 AKDLVRTRRYVKKFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQI 122
Query: 477 AKVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 656
K++ +F++QS +DM EMM+++ID+ + ++ EEE++ + +QVLDE+G+ ++ +LS+
Sbjct: 123 QKIMMEFERQSEIMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLSDELSNL 182
Query: 657 PKGRIATKTAAPPASTTSNSSESSEVDGLEKRLASLRR 770
P + AA + + ++ D LE+RL +LRR
Sbjct: 183 PATGGSLSVAAGKKAEPQPTLADADAD-LEERLNNLRR 219
>sp|O43633|CHM2A_HUMAN Charged multivesicular body protein 2a OS=Homo sapiens
GN=CHMP2A PE=1 SV=1
Length = 222
Score = 149 bits (374), Expect = 4e-035
Identities = 77/219 (35%), Positives = 139/219 (63%), Gaps = 3/219 (1%)
Frame = +3
Query: 120 IFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKILA 299
+F ++ TP++ LR ++R ++ A R ++RE L+ +EK+++A+IKK AK G A +I+A
Sbjct: 4 LFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMA 63
Query: 300 RQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQA 479
+ LVR R+ + RA I+ V+ Q L ++ S++ MKG TKAM MN+Q+ +
Sbjct: 64 KDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQ 123
Query: 480 KVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSAP 659
K++ +F++Q+ +DM EMM+++ID+ + +E EEE++ + +QVLDE+G+ + +LS+ P
Sbjct: 124 KIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLP 183
Query: 660 K--GRIATKTAAPPASTTSNSSESSEVDGLEKRLASLRR 770
G ++ A +++ ++ D LE+RL +LRR
Sbjct: 184 STGGSLSVAAGGKKAEAAASALADADAD-LEERLKNLRR 221
>sp|Q6IP52|CHM2A_XENLA Charged multivesicular body protein 2a OS=Xenopus laevis
GN=chmp2a PE=2 SV=1
Length = 220
Score = 149 bits (374), Expect = 4e-035
Identities = 78/217 (35%), Positives = 136/217 (62%), Gaps = 1/217 (0%)
Frame = +3
Query: 120 IFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKILA 299
+F ++ TP++ LR ++R ++ A R ++RE L+ +EK+++A+IKK AK G A KI+A
Sbjct: 4 LFGRRKTPEELLRQNQRALNRAMRELDRERQKLEQQEKKIIADIKKMAKQGQMDAVKIMA 63
Query: 300 RQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQA 479
+ LVR R+ + RA I+ V+ Q L ++ S++ MKG TKAM MN+Q+ +
Sbjct: 64 KDLVRTRRYVKKFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQIQ 123
Query: 480 KVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSAP 659
K++ +F+KQS +DM EMM+++ID+ + ++ EEE++ + +QVLDE+G+ + +LS+ P
Sbjct: 124 KIMMEFEKQSEIMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLTDELSNLP 183
Query: 660 KGRIATKTAAPPASTTSNSSESSEVDGLEKRLASLRR 770
+ A + + ++ D LE+RL +LRR
Sbjct: 184 STGGSLSVAGAKKGEATAALADADAD-LEERLNNLRR 219
>sp|Q6NXD2|CHM2B_DANRE Charged multivesicular body protein 2b OS=Danio rerio
GN=chmp2b PE=2 SV=1
Length = 214
Score = 147 bits (370), Expect = 1e-034
Identities = 79/213 (37%), Positives = 138/213 (64%), Gaps = 7/213 (3%)
Frame = +3
Query: 117 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 296
++F+KKT D ++ +E+ R I R+ ++L+ +EK+L EIKK AKTGN A K+L
Sbjct: 3 SLFKKKTV-DDVIKEQNKELRGTQRQIARDRTALEKQEKQLEMEIKKMAKTGNRDACKVL 61
Query: 297 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 476
A+QLV++R+Q T +++ ++T T+ + + ++ M TK M A+NK+M P K
Sbjct: 62 AKQLVQVRKQKTRTYAVSSKVTSMSTQTKLMNSQMKMAGAMATTTKTMQAVNKKMDPKKT 121
Query: 477 AKVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 656
+ +++FQK++A +DMT EMM++++DE + EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 MQTLQNFQKETAKMDMTEEMMNDTLDEIFEDSGDEEESQDIVNQVLDEIGIEISGKMAHA 181
Query: 657 PKGRIATKTAAPPASTTSNSSESSEVDGLEKRL 755
P A KT P++ T+ + S+ D +E++L
Sbjct: 182 PSA--ARKT---PSAATAKADGISDED-IERQL 208
>sp|Q5F3A2|CHM2B_CHICK Charged multivesicular body protein 2b OS=Gallus gallus
GN=CHMP2B PE=2 SV=1
Length = 214
Score = 144 bits (361), Expect = 1e-033
Identities = 73/205 (35%), Positives = 130/205 (63%), Gaps = 5/205 (2%)
Frame = +3
Query: 117 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 296
++F+KKT D ++ RE+ R I R+ ++L+ +E++L EIKK AKTGN+ A K+L
Sbjct: 3 SLFKKKTV-DDIIKEQNRELRGTQRTITRDRAALEKQERQLELEIKKMAKTGNKEACKVL 61
Query: 297 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 476
A+QLV+LR+Q +++ ++T T+ + + ++ M K M A+NK+M P K
Sbjct: 62 AKQLVQLRKQKNRTYAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKT 121
Query: 477 AKVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 656
+ +++FQK++ ++MT EM+++++D+ D + EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 LQTMQNFQKENMKMEMTEEMINDTLDDIFDASDEEEESQDIVNQVLDEIGIEISGKMAKA 181
Query: 657 PKGRIATKTAAPPASTTSNSSESSE 731
P + P AST+ S+ S E
Sbjct: 182 P----SAARGLPSASTSKASTISDE 202
>sp|Q7SYR0|CH2BA_XENLA Charged multivesicular body protein 2b-A OS=Xenopus
laevis GN=chmp2b-a PE=2 SV=1
Length = 214
Score = 143 bits (360), Expect = 2e-033
Identities = 71/202 (35%), Positives = 127/202 (62%), Gaps = 1/202 (0%)
Frame = +3
Query: 117 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 296
++F+KKT D ++ +E+ R I R+ ++L+ +EK+L EIKK AK GN+ A K+L
Sbjct: 3 SLFKKKTV-DDIIKDQNKELKGQQRAITRDRTALEKQEKQLEMEIKKMAKAGNKDACKVL 61
Query: 297 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 476
A+QLV+LR+Q T +++ ++T T+ + + ++ M K M A+NK+M P K
Sbjct: 62 AKQLVQLRKQKTRTYAVSSKVTSMSTQTKVMSSQMKMAGAMSTTAKTMQAVNKKMDPQKT 121
Query: 477 AKVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 656
+ +++FQK++ ++MT EM+++++D+ D E EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 LQTMQNFQKENMKMEMTEEMINDTLDDIFDASEDEEESQDIVNQVLDEIGIEISGKMAKA 181
Query: 657 PKGRIATKTAAPPASTTSNSSE 722
P +A+ ST + E
Sbjct: 182 PSAAKGLPSASASKSTGISDEE 203
>sp|Q66IV6|CH2BB_XENLA Charged multivesicular body protein 2b-B OS=Xenopus
laevis GN=chmp2b-b PE=2 SV=1
Length = 214
Score = 143 bits (360), Expect = 2e-033
Identities = 74/213 (34%), Positives = 134/213 (62%), Gaps = 7/213 (3%)
Frame = +3
Query: 117 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 296
++F+KKT D +R +E+ R I R+ ++L+ +EK+L EIKK AKTGN+ A ++L
Sbjct: 3 SLFKKKTV-DDIIREQNKELRGTQRAITRDRAALEKQEKQLEMEIKKMAKTGNKDACRVL 61
Query: 297 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 476
A+QLV+LR+Q T +++ ++T T+ + + ++ M K M A+NK+M P K
Sbjct: 62 AKQLVQLRKQKTRTYAVSSKVTSMSTQTKVMSSQMKMAGAMSTTAKTMQAVNKKMDPQKT 121
Query: 477 AKVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 656
+ +++FQK++ ++MT EM+++++D+ D E EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 LQTMQNFQKENMKMEMTDEMINDTLDDIFDASEDEEESQDIVNQVLDEIGIEISGKMAKA 181
Query: 657 PKGRIATKTAAPPASTTSNSSESSEVDGLEKRL 755
P A ST++ S+ + +E++L
Sbjct: 182 P------SAAKGLPSTSAAKSKGISDEEIERQL 208
>sp|Q5ZHN1|CHM2A_CHICK Charged multivesicular body protein 2a OS=Gallus gallus
GN=CHMP2A PE=2 SV=1
Length = 220
Score = 143 bits (358), Expect = 3e-033
Identities = 73/217 (33%), Positives = 136/217 (62%), Gaps = 1/217 (0%)
Frame = +3
Query: 120 IFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKILA 299
+F ++ TP++ LR ++R ++ A R ++RE L+ +EK+++ +IKK AK G A KI+A
Sbjct: 4 LFGRRKTPEELLRQNQRALTRAMRELDRERQKLEAQEKKIIIDIKKMAKQGQMDAVKIMA 63
Query: 300 RQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQA 479
+ LVR R+ + RA ++ V+ Q L ++ S++ MKG TKAM MN+Q+ +
Sbjct: 64 KDLVRTRRYVKKFITMRANVQAVSLKIQTLKSNNSMALAMKGVTKAMATMNRQLKLPQIQ 123
Query: 480 KVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSAP 659
K++ +F+KQ+ +DM E+M+++ID+ + ++ EEE++ + +QVLDE+G+ + +L++ P
Sbjct: 124 KIMMEFEKQAGIMDMKEELMNDAIDDAMGDEDDEEESDAVVSQVLDELGLNLTDELATLP 183
Query: 660 KGRIATKTAAPPASTTSNSSESSEVDGLEKRLASLRR 770
+ A+ + + ++ D LE+RL +LRR
Sbjct: 184 PPGGSLAAGEGRAAEAAAALADADAD-LEERLKNLRR 219
>sp|Q3SX42|CHM2B_BOVIN Charged multivesicular body protein 2b OS=Bos taurus
GN=CHMP2B PE=2 SV=1
Length = 213
Score = 143 bits (358), Expect = 3e-033
Identities = 71/207 (34%), Positives = 131/207 (63%), Gaps = 5/207 (2%)
Frame = +3
Query: 117 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 296
++F+KKT D ++ RE+ R I R+ ++L+ +EK+L EIKK AK GN+ A ++L
Sbjct: 3 SLFKKKTV-DDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACRVL 61
Query: 297 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 476
A+QLV LR+Q T +++ ++T T+ + + ++ M K M A+NK+M P K
Sbjct: 62 AKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKT 121
Query: 477 AKVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 656
+ +++FQK++ ++MT EM+++++D+ D + EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 LQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKA 181
Query: 657 PKGRIATKTAAPPASTTSNSSESSEVD 737
P + + P AST+ ++ E++
Sbjct: 182 P----SAARSLPSASTSKSTISDEEIE 204
>sp|Q9UQN3|CHM2B_HUMAN Charged multivesicular body protein 2b OS=Homo sapiens
GN=CHMP2B PE=1 SV=1
Length = 213
Score = 143 bits (358), Expect = 3e-033
Identities = 72/207 (34%), Positives = 130/207 (62%), Gaps = 5/207 (2%)
Frame = +3
Query: 117 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 296
++F+KKT D ++ RE+ R I R+ ++L+ +EK+L EIKK AK GN+ A K+L
Sbjct: 3 SLFKKKTV-DDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVL 61
Query: 297 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 476
A+QLV LR+Q T +++ ++T T+ + + ++ M K M A+NK+M P K
Sbjct: 62 AKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKT 121
Query: 477 AKVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 656
+ +++FQK++ ++MT EM+++++D+ D + EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 LQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKA 181
Query: 657 PKGRIATKTAAPPASTTSNSSESSEVD 737
P + + P AST+ + E++
Sbjct: 182 P----SAARSLPSASTSKATISDEEIE 204
>sp|Q5RAV2|CHM2B_PONAB Charged multivesicular body protein 2b OS=Pongo abelii
GN=CHMP2B PE=2 SV=1
Length = 213
Score = 143 bits (358), Expect = 3e-033
Identities = 72/207 (34%), Positives = 130/207 (62%), Gaps = 5/207 (2%)
Frame = +3
Query: 117 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 296
++F+KKT D ++ RE+ R I R+ ++L+ +EK+L EIKK AK GN+ A K+L
Sbjct: 3 SLFKKKTV-DDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVL 61
Query: 297 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 476
A+QLV LR+Q T +++ ++T T+ + + ++ M K M A+NK+M P K
Sbjct: 62 AKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKT 121
Query: 477 AKVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 656
+ +++FQK++ ++MT EM+++++D+ D + EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 LQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKA 181
Query: 657 PKGRIATKTAAPPASTTSNSSESSEVD 737
P + + P AST+ + E++
Sbjct: 182 P----SAARSLPSASTSKATISDEEIE 204
>sp|Q8BJF9|CHM2B_MOUSE Charged multivesicular body protein 2b OS=Mus musculus
GN=Chmp2b PE=2 SV=1
Length = 213
Score = 141 bits (355), Expect = 6e-033
Identities = 71/207 (34%), Positives = 130/207 (62%), Gaps = 5/207 (2%)
Frame = +3
Query: 117 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 296
++F+KKT D ++ RE+ R I R+ ++L+ +EK+L EIKK AK GN+ A ++L
Sbjct: 3 SLFKKKTV-DDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACRVL 61
Query: 297 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 476
A+QLV LR+Q T +++ ++T T+ + + ++ M K M A+NK+M P K
Sbjct: 62 AKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKT 121
Query: 477 AKVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 656
+ +++FQK++ ++MT EM+++++D+ D + EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 LQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKA 181
Query: 657 PKGRIATKTAAPPASTTSNSSESSEVD 737
P + + P AST+ + E++
Sbjct: 182 P----SAARSLPSASTSKATISDEEIE 204
>sp|Q6NVL7|CHM2B_XENTR Charged multivesicular body protein 2b OS=Xenopus
tropicalis GN=chmp2b PE=2 SV=1
Length = 214
Score = 141 bits (355), Expect = 6e-033
Identities = 73/213 (34%), Positives = 136/213 (63%), Gaps = 7/213 (3%)
Frame = +3
Query: 117 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 296
++F+KKT D +R +E+ R I R+ ++L+ +EK+L EIKK AK GN+ A ++L
Sbjct: 3 SLFKKKTV-DDIIREQNKELRGTQRAITRDRAALEKQEKQLEMEIKKMAKAGNKDACRVL 61
Query: 297 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 476
A+QLV+LR+Q T +++ ++T T+ + + ++ M K M A+NK+M P K
Sbjct: 62 AKQLVQLRKQKTRTYAVSSKVTSMSTQTKVMSSQMKMAGAMSTTAKTMQAVNKKMDPQKT 121
Query: 477 AKVIKDFQKQSAHLDMTIEMMSESIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 656
+ +++FQK++ ++MT EM+++++D+ D + EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 LQTMQNFQKENMKMEMTEEMINDTLDDIFDASDDEEESQDIVNQVLDEIGIEISGKMAKA 181
Query: 657 PKGRIATKTAAPPASTTSNSSESSEVDGLEKRL 755
P + P+++ S SS S+ + +E++L
Sbjct: 182 P-----SAAKGLPSTSASKSSGISD-EEIERQL 208
>sp|P36108|DID4_YEAST DOA4-independent degradation protein 4 OS=Saccharomyces
cerevisiae GN=DID4 PE=1 SV=2
Length = 232
Score = 131 bits (329), Expect = 7e-030
Identities = 73/224 (32%), Positives = 126/224 (56%), Gaps = 7/224 (3%)
Frame = +3
Query: 120 IFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKILA 299
+F K TP++ L+ ++R + R +ERE L++++K+LV+EIKK+AK G AA K+ A
Sbjct: 7 VFGKNVTPQERLKKNQRALERTQRELEREKRKLELQDKKLVSEIKKSAKNGQVAAAKVQA 66
Query: 300 RQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQA 479
+ LVR R I +AQ++ ++ QA+ +S ++ M AT + MN+ M +
Sbjct: 67 KDLVRTRNYIQKFDNMKAQLQAISLRIQAVRSSDQMTRSMSEATGLLAGMNRTMNLPQLQ 126
Query: 480 KVIKDFQKQSAHLDMTIEMMSESIDETL-DKDEAEEETEDLTNQVLDEIGVGVASQLSSA 656
++ +F+KQS + E M E+ID + D+ + +EE +++ N+VLDEIGV + SQL S
Sbjct: 127 RISMEFEKQSDLMGQRQEFMDEAIDNVMGDEVDEDEEADEIVNKVLDEIGVDLNSQLQST 186
Query: 657 PKGRIA------TKTAAPPASTTSNSSESSEVDGLEKRLASLRR 770
P+ ++ T P + + D L+ RL +L++
Sbjct: 187 PQNLVSNAPIAETAMGIPEPIGAGSEFHGNPDDDLQARLNTLKK 230
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106,282,147,502
Number of Sequences: 518415
Number of Extensions: 106282147502
Number of Successful Extensions: 672117376
Number of sequences better than 0.0: 0
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