BLASTX 7.6.2
Query= UN25425 /QuerySize=1316
(1315 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q94JW0|DOHH_ARATH Deoxyhypusine hydroxylase OS=Arabidopsis th... 531 5e-150
sp|Q2QXB3|DOHH1_ORYSJ Deoxyhypusine hydroxylase-A OS=Oryza sativ... 408 8e-113
sp|Q2QLW3|DOHH2_ORYSJ Deoxyhypusine hydroxylase-B OS=Oryza sativ... 406 3e-112
sp|Q5ZIP3|DOHH_CHICK Deoxyhypusine hydroxylase OS=Gallus gallus ... 257 1e-067
sp|Q5PPJ4|DOHH_RAT Deoxyhypusine hydroxylase OS=Rattus norvegicu... 257 2e-067
sp|Q7ZUX6|DOHH_DANRE Deoxyhypusine hydroxylase OS=Danio rerio GN... 254 1e-066
sp|Q99LN9|DOHH_MOUSE Deoxyhypusine hydroxylase OS=Mus musculus G... 254 1e-066
sp|Q9BU89|DOHH_HUMAN Deoxyhypusine hydroxylase OS=Homo sapiens G... 250 2e-065
sp|Q0VC53|DOHH_BOVIN Deoxyhypusine hydroxylase OS=Bos taurus GN=... 248 1e-064
sp|Q66KT3|DOHH_XENLA Deoxyhypusine hydroxylase OS=Xenopus laevis... 245 7e-064
sp|Q9V9U4|DOHH_DROME Deoxyhypusine hydroxylase OS=Drosophila mel... 228 7e-059
sp|Q297S2|DOHH_DROPS Deoxyhypusine hydroxylase OS=Drosophila pse... 226 3e-058
sp|Q9P6K9|DOHH_SCHPO Deoxyhypusine hydroxylase OS=Schizosaccharo... 214 1e-054
sp|Q59Z14|DOHH_CANAL Deoxyhypusine hydroxylase OS=Candida albica... 213 3e-054
sp|Q6CHJ7|DOHH_YARLI Deoxyhypusine hydroxylase OS=Yarrowia lipol... 210 2e-053
sp|Q6FUV3|DOHH_CANGA Deoxyhypusine hydroxylase OS=Candida glabra... 198 1e-049
sp|Q6CV81|DOHH_KLULA Deoxyhypusine hydroxylase OS=Kluyveromyces ... 198 1e-049
sp|P47120|DOHH_YEAST Deoxyhypusine hydroxylase OS=Saccharomyces ... 188 8e-047
sp|Q17949|DOHH_CAEEL Deoxyhypusine hydroxylase OS=Caenorhabditis... 115 8e-025
>sp|Q94JW0|DOHH_ARATH Deoxyhypusine hydroxylase OS=Arabidopsis thaliana
GN=At3g58180 PE=2 SV=1
Length = 314
Score = 531 bits (1367), Expect = 5e-150
Identities = 278/313 (88%), Positives = 295/313 (94%), Gaps = 5/313 (1%)
Frame = +3
Query: 117 NGGVS---KLEKFLCERLLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAH 287
NG VS LEKFLCERL+DQSQPISERFRALFSLRNLKGP PRNALILASRDSSNLLAH
Sbjct: 4 NGSVSSMVNLEKFLCERLVDQSQPISERFRALFSLRNLKGPGPRNALILASRDSSNLLAH 63
Query: 288 ESAFALGQMQDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPA 467
E+AFALGQMQDAEA+PALESVLNDMSLHPIVRHEAAEALGAIGLAGN ILKKSL DPA
Sbjct: 64 EAAFALGQMQDAEAIPALESVLNDMSLHPIVRHEAAEALGAIGLAGNVNILKKSLSSDPA 123
Query: 468 QEVRETCELALKRIEELSSVVDAEKNQSDTTERSPFMSVDPAAPAAAFSSVHQLREILMD 647
QEVRETCELALKRIE++S+ VDAE NQS TTE+SPFMSVDPA PAA+FSSVHQLR++L+D
Sbjct: 124 QEVRETCELALKRIEDMSN-VDAE-NQSSTTEKSPFMSVDPAGPAASFSSVHQLRQVLLD 181
Query: 648 ETKGMYERYAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALATPSK 827
ETKGMYERYAALFALRNHGGEEAVSAIVDSLSA SALLRHEVAYVLGQLQ+K ALAT SK
Sbjct: 182 ETKGMYERYAALFALRNHGGEEAVSAIVDSLSASSALLRHEVAYVLGQLQSKTALATLSK 241
Query: 828 ILRDLKEHPMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGK 1007
+LRD+ EHPMVRHEAAEALGSIADEQSIALL+EFS+DPEPIV+QSCEVALSMLEFENSGK
Sbjct: 242 VLRDVNEHPMVRHEAAEALGSIADEQSIALLEEFSKDPEPIVAQSCEVALSMLEFENSGK 301
Query: 1008 SFEFFFTQDPLVH 1046
SFEFFFTQDPLVH
Sbjct: 302 SFEFFFTQDPLVH 314
>sp|Q2QXB3|DOHH1_ORYSJ Deoxyhypusine hydroxylase-A OS=Oryza sativa subsp.
japonica GN=Os12g0163300 PE=2 SV=1
Length = 319
Score = 408 bits (1046), Expect = 8e-113
Identities = 217/317 (68%), Positives = 257/317 (81%), Gaps = 5/317 (1%)
Frame = +3
Query: 102 ASPTENGGVSKLEKFLCERLLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLL 281
A+ + G ++EKFLC+ LLD +QPI+ERFRALFSLRNL G PR AL+ A+RDSSNLL
Sbjct: 7 AASSTFGPTPEMEKFLCDLLLDTAQPIAERFRALFSLRNLHGDGPRCALLQAARDSSNLL 66
Query: 282 AHESAFALGQMQDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILD 461
AHE+AFALGQMQDAEA+PALE+VL D+SLHPIVRHEAAEALGAIGL + +L++SL D
Sbjct: 67 AHEAAFALGQMQDAEAIPALEAVLKDLSLHPIVRHEAAEALGAIGLEKSIPLLEESLAAD 126
Query: 462 PAQEVRETCELALKRIEELSSVVDAEKNQSDTTERSPFMSVDPAAPAAAFSSVHQLREIL 641
PA EV+ETCELAL+RIE+ + S++T SPF+SVDPA PA SVHQLREIL
Sbjct: 127 PAVEVQETCELALRRIEQQKNA-----GVSESTTISPFLSVDPALPAKQGLSVHQLREIL 181
Query: 642 MDETKGMYERYAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALATP 821
++E + MYERYAALFALRN + AVSAIV +L A SALL+HEVAYVLGQLQNKAA
Sbjct: 182 LNEQESMYERYAALFALRNDSRDAAVSAIVAALGAKSALLKHEVAYVLGQLQNKAASDAL 241
Query: 822 SKILRDLKEHPMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENS 1001
S +L+++ EHPMVRHEAAEALGSIAD++SIALL+EF++DPEPIVSQSCEVALSMLE+E S
Sbjct: 242 STVLKNVDEHPMVRHEAAEALGSIADQESIALLEEFAKDPEPIVSQSCEVALSMLEYERS 301
Query: 1002 GKSFEFFFTQDPLVH*E 1052
GKSFEF F Q P V E
Sbjct: 302 GKSFEFLFLQTPGVQQE 318
>sp|Q2QLW3|DOHH2_ORYSJ Deoxyhypusine hydroxylase-B OS=Oryza sativa subsp.
japonica GN=Os12g0626100 PE=2 SV=1
Length = 302
Score = 406 bits (1041), Expect = 3e-112
Identities = 214/308 (69%), Positives = 254/308 (82%), Gaps = 9/308 (2%)
Frame = +3
Query: 135 LEKFLCERLLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHESAFALGQM 314
+E FLC+RLLD +QPI+ERFRALFSLRNL+G APR AL+ A+RDSSNLLAHE+AFALGQM
Sbjct: 1 MEGFLCDRLLDAAQPIAERFRALFSLRNLRGDAPRRALLQAARDSSNLLAHEAAFALGQM 60
Query: 315 QDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCEL 494
QDAEA+PALE+VL D+SLHPIVRHEAAEALGAIGL + +L++SL +DPA EV+ETCEL
Sbjct: 61 QDAEAIPALEAVLKDLSLHPIVRHEAAEALGAIGLEKSISLLEESLAVDPAVEVQETCEL 120
Query: 495 ALKRIEELSSVVDAEKNQS--DTTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYE 668
A++RIEE +KN S ++ SPF+SVDPA PA V QLRE+L++E + MYE
Sbjct: 121 AIRRIEE-------QKNTSGVESATVSPFLSVDPALPAKQGLPVEQLRELLLNEQESMYE 173
Query: 669 RYAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALATPSKILRDLKE 848
RYAALFALRN G+ AVSAIV +L SALLRHEVAYVLGQLQNKAA S +L+++ E
Sbjct: 174 RYAALFALRNDSGDAAVSAIVAALGVKSALLRHEVAYVLGQLQNKAASDALSTVLKNVDE 233
Query: 849 HPMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGKSFEFFFT 1028
HPMVRHEAAEALGSIAD++SIALL+EF++DPEPIVSQSCEVALSMLE+E SGK+FEF F
Sbjct: 234 HPMVRHEAAEALGSIADQESIALLEEFAKDPEPIVSQSCEVALSMLEYERSGKAFEFLFP 293
Query: 1029 QDPLVH*E 1052
Q P V E
Sbjct: 294 QTPQVQQE 301
>sp|Q5ZIP3|DOHH_CHICK Deoxyhypusine hydroxylase OS=Gallus gallus GN=DOHH PE=2
SV=1
Length = 299
Score = 257 bits (656), Expect = 1e-067
Identities = 143/287 (49%), Positives = 190/287 (66%), Gaps = 10/287 (3%)
Frame = +3
Query: 159 LLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHESAFALGQMQDAEAVPA 338
LLD +QP+ RFRALF+LRNL GPA + ++ DSS LL HE AF LGQM+D A+PA
Sbjct: 14 LLDAAQPLPARFRALFTLRNLGGPAAIDCIVRGFADSSALLKHELAFCLGQMRDRAAIPA 73
Query: 339 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKRIEEL 518
L VL D P+VRHEA EALGAIG ++L++ DP EV ETC+LA++R+E L
Sbjct: 74 LLGVLQDSQQEPMVRHEAGEALGAIGDPEVLDVLRR-YSEDPVVEVAETCQLAVRRLEWL 132
Query: 519 SSVVDAEKNQSDTTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFALRN 698
+ + SP+ SVDPA PA + V LR +L+DE++ +++RY A+FALRN
Sbjct: 133 -------QEHGEEPGSSPYRSVDPAPPAEE-TDVATLRAVLLDESRPLFDRYRAMFALRN 184
Query: 699 HGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALATPSKILRDLKEHPMVRHEAAE 878
GG +AV A+ D L A SAL RHE+ YVLGQ+Q++A + + LR E+PMVRHE AE
Sbjct: 185 LGGRDAVLALADGLRAGSALFRHEIGYVLGQMQDEACVPQLTAALRSRAENPMVRHECAE 244
Query: 879 ALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGKSFEF 1019
ALGSIA + L+ F++D E +V +SCEVAL M E+EN G F++
Sbjct: 245 ALGSIARPSCLETLRAFAQDEERVVRESCEVALDMYEYEN-GPQFQY 290
>sp|Q5PPJ4|DOHH_RAT Deoxyhypusine hydroxylase OS=Rattus norvegicus GN=Dohh PE=2
SV=1
Length = 302
Score = 257 bits (655), Expect = 2e-067
Identities = 145/289 (50%), Positives = 192/289 (66%), Gaps = 13/289 (4%)
Frame = +3
Query: 159 LLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHESAFALGQMQDAEAVPA 338
L+D +QP+ RFRALF+LR L GP + + DSS LL HE A+ LGQM+D A+P
Sbjct: 14 LVDSTQPLQARFRALFTLRGLGGPDAISWISRGFEDSSALLKHELAYCLGQMRDPRAIPV 73
Query: 339 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEI--LKKSLILDPAQEVRETCELALKRIE 512
L SVL D + P+VRHEA EALGAI GN ++ L K DP EV ETC+LA++R+E
Sbjct: 74 LVSVLQDRNQEPMVRHEAGEALGAI---GNPKVLGLLKQYSTDPVVEVAETCQLAVRRLE 130
Query: 513 ELSSVVDAEKNQSDTTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFAL 692
L +++ + T P++SVDPA PAA V +LRE L+DE + ++ERY A+FAL
Sbjct: 131 WL------QQHPGEATCAGPYLSVDPAPPAAE-GDVGRLRETLLDEAQPLFERYRAMFAL 183
Query: 693 RNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALATPSKILRDLKEHPMVRHEA 872
RN GG+EA A+ + L SAL RHEV YVLGQLQ++AA++ + L E PMVRHE
Sbjct: 184 RNVGGKEAALALAEGLKCGSALFRHEVGYVLGQLQHEAAVSELAATLARTTESPMVRHEC 243
Query: 873 AEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGKSFEF 1019
AEALG+IA +A L+E+ DPE +V +SCEVAL M E+EN G+ F++
Sbjct: 244 AEALGAIARPACLAALREYITDPERVVRESCEVALDMYEYEN-GQDFQY 291
>sp|Q7ZUX6|DOHH_DANRE Deoxyhypusine hydroxylase OS=Danio rerio GN=dohh PE=2
SV=1
Length = 305
Score = 254 bits (647), Expect = 1e-066
Identities = 142/283 (50%), Positives = 187/283 (66%), Gaps = 5/283 (1%)
Frame = +3
Query: 159 LLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHESAFALGQMQDAEAVPA 338
L++ Q ++ RFRALF+LRNL G + A D S LL HE A+ LGQMQD A+P
Sbjct: 14 LVNTKQDLTTRFRALFTLRNLGGAEAVKWISEAFVDESALLKHELAYCLGQMQDESAIPT 73
Query: 339 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKRIEEL 518
LE+VL D + P+VRHEA EALGAIG E+LKK DP EV ETC+LA+KR+E L
Sbjct: 74 LEAVLKDTNQEPMVRHEAGEALGAIGNPKVLELLKK-YAEDPVIEVAETCQLAVKRLEWL 132
Query: 519 SSVVDAEKNQSDTTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFALRN 698
++ + D T+ +P+ SVDPA PA SV +LR L+DET +++RY A+FALRN
Sbjct: 133 ---MNGGEQTKDGTDENPYCSVDPAPPAQR-KSVPELRTQLLDETLPLFDRYRAMFALRN 188
Query: 699 HGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALATPSKILRDLKEHPMVRHEAAE 878
G EEAV A+ D L SAL RHE+ YVLGQ+Q++A++ L + E+ MVRHE AE
Sbjct: 189 LGTEEAVLALGDGLQCSSALFRHEIGYVLGQIQHEASIPQLQAALEKMDENAMVRHECAE 248
Query: 879 ALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGK 1007
ALGSI E + +L+ + +D E +V +SCEVAL MLE+ENS +
Sbjct: 249 ALGSIGKEPCVQILERYRKDQERVVKESCEVALDMLEYENSSQ 291
>sp|Q99LN9|DOHH_MOUSE Deoxyhypusine hydroxylase OS=Mus musculus GN=Dohh PE=2
SV=2
Length = 302
Score = 254 bits (647), Expect = 1e-066
Identities = 145/283 (51%), Positives = 184/283 (65%), Gaps = 12/283 (4%)
Frame = +3
Query: 159 LLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHESAFALGQMQDAEAVPA 338
L+D QP+ RFRALF+LR L GP + + DSS LL HE A+ LGQM+DA A+P
Sbjct: 14 LVDPKQPLQARFRALFTLRGLGGPDAISWISRGFEDSSALLKHELAYCLGQMRDARAIPV 73
Query: 339 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEI--LKKSLILDPAQEVRETCELALKRIE 512
L VL D S P+VRHEA EALGAI GN E+ L K DP EV ETC+LA+ R+E
Sbjct: 74 LADVLQDTSQEPMVRHEAGEALGAI---GNPEVLGLLKQYSTDPVVEVAETCQLAVGRLE 130
Query: 513 ELSSVVDAEKNQSDTTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFAL 692
L +++ + T P++SVDPA PAA V +LRE L+DE + ++ERY A+FAL
Sbjct: 131 WL------QQHPGEATCAGPYLSVDPAPPAAE-QDVGRLREALLDEARPLFERYRAMFAL 183
Query: 693 RNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALATPSKILRDLKEHPMVRHEA 872
RN GG+EA A+ + L SAL RHEV YVLGQLQ++AA+ + L E PMVRHE
Sbjct: 184 RNVGGKEAALALAEGLQCGSALFRHEVGYVLGQLQHEAAVPGLAATLARTTESPMVRHEC 243
Query: 873 AEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENS 1001
AEALG+IA +A L+E DPE +V +SCEVAL M E+E+S
Sbjct: 244 AEALGAIARPACLAALREHIEDPEQVVRESCEVALDMYEYESS 286
>sp|Q9BU89|DOHH_HUMAN Deoxyhypusine hydroxylase OS=Homo sapiens GN=DOHH PE=1
SV=1
Length = 302
Score = 250 bits (637), Expect = 2e-065
Identities = 145/289 (50%), Positives = 185/289 (64%), Gaps = 10/289 (3%)
Frame = +3
Query: 153 ERLLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHESAFALGQMQDAEAV 332
+ L+D QP+ RFRALF+LR L GP + A D S LL HE A+ LGQMQDA A+
Sbjct: 12 QTLVDPKQPLQARFRALFTLRGLGGPGAIAWISQAFDDDSALLKHELAYCLGQMQDARAI 71
Query: 333 PALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKRIE 512
P L VL D P+VRHEA EALGAIG EILK+ DP EV ETC+LA++R+E
Sbjct: 72 PMLVDVLQDTRQEPMVRHEAGEALGAIGDPEVLEILKQ-YSSDPVIEVAETCQLAVRRLE 130
Query: 513 ELSSVVDAEKNQSDTTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFAL 692
L + P++SVDPA PA V +LRE L+DE++ ++ERY A+FAL
Sbjct: 131 WL-------QQHGGEPAAGPYLSVDPAPPAEE-RDVGRLREALLDESRPLFERYRAMFAL 182
Query: 693 RNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALATPSKILRDLKEHPMVRHEA 872
RN GGEEA A+ + L SAL RHEV YVLGQLQ++AA+ + L E+PMVRHE
Sbjct: 183 RNAGGEEAALALAEGLHCGSALFRHEVGYVLGQLQHEAAVPQLAAALARCTENPMVRHEC 242
Query: 873 AEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGKSFEF 1019
AEALG+IA +A LQ + DPE +V +SCEVAL M E E +G++F++
Sbjct: 243 AEALGAIARPACLAALQAHADDPERVVRESCEVALDMYEHE-TGRAFQY 290
>sp|Q0VC53|DOHH_BOVIN Deoxyhypusine hydroxylase OS=Bos taurus GN=DOHH PE=1 SV=1
Length = 303
Score = 248 bits (631), Expect = 1e-064
Identities = 139/289 (48%), Positives = 188/289 (65%), Gaps = 9/289 (3%)
Frame = +3
Query: 153 ERLLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHESAFALGQMQDAEAV 332
+ L+D QP+ RFRALF+LR L GP + + A D S LL HE A+ LGQMQD A+
Sbjct: 12 QTLVDPGQPLQARFRALFTLRGLGGPVAISWISRAFDDDSALLKHELAYCLGQMQDRRAI 71
Query: 333 PALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKRIE 512
P L VL D P+VRHEA EALGAIG EILK+ DP EV ETC+LA++R+E
Sbjct: 72 PVLLDVLRDTRQEPMVRHEAGEALGAIGDPEVLEILKQ-YSTDPVVEVAETCQLAVRRLE 130
Query: 513 ELSSVVDAEKNQSDTTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFAL 692
L +++ ++ R P++SVDPA PA + QLRE L+DE + +++RY A+FAL
Sbjct: 131 WL------QQHGGESAVRGPYLSVDPAPPAEE-RDLGQLREALLDEARPLFDRYRAMFAL 183
Query: 693 RNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALATPSKILRDLKEHPMVRHEA 872
R+ GG+EA A+ + L SAL RHE+ YVLGQ+Q++AA+ + L E+PMVRHE
Sbjct: 184 RDAGGKEAALALAEGLRCGSALFRHEIGYVLGQMQHEAAVPQLAAALAQPTENPMVRHEC 243
Query: 873 AEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGKSFEF 1019
AEALG+IA +A L+ DPE +V +SCEVAL M E+E +G +F++
Sbjct: 244 AEALGAIARPACLAALRAHVADPERVVRESCEVALDMYEYE-TGSTFQY 291
>sp|Q66KT3|DOHH_XENLA Deoxyhypusine hydroxylase OS=Xenopus laevis GN=dohh PE=2
SV=1
Length = 303
Score = 245 bits (624), Expect = 7e-064
Identities = 142/286 (49%), Positives = 184/286 (64%), Gaps = 9/286 (3%)
Frame = +3
Query: 147 LCERLLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHESAFALGQMQDAE 326
L + L+D +P+ RFRALF+LRNL G + + +D S LL HE A+ LGQM+D
Sbjct: 12 LGQLLIDPGKPLPLRFRALFTLRNLGGAEAIDCIGRGFQDESALLKHELAYCLGQMKDRR 71
Query: 327 AVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKR 506
A+P L+ VL D P+VRHEA EALGAIG E+L++ DP EV ETC+LA+ R
Sbjct: 72 ALPVLKQVLQDRQQEPMVRHEAGEALGAIGDPEVLELLRE-YAQDPVIEVAETCQLAVSR 130
Query: 507 IEELSSVVDAEKNQSDTTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALF 686
IE L +KN D+ + +P++SVDPA PA V LR L+DET ++ RY A+F
Sbjct: 131 IEWL------QKN-PDSPDTNPYLSVDPAPPAEE-KDVPTLRATLLDETCPLFHRYRAMF 182
Query: 687 ALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALATPSKILRDLKEHPMVRH 866
ALRN GGEEAV A+ D L +L RHE+ YVLGQ+Q+KAA+ S L +E+PMVRH
Sbjct: 183 ALRNIGGEEAVLALADGLQIGGSLFRHEIGYVLGQMQHKAAVPGLSAALERFEENPMVRH 242
Query: 867 EAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSG 1004
E AEALGSIA E + L+ D E +V +SCEVAL M ++ENSG
Sbjct: 243 ECAEALGSIAHEDCLKALRAHVGDGERVVRESCEVALDMHDYENSG 288
Score = 119 bits (296), Expect = 7e-026
Identities = 58/131 (44%), Positives = 92/131 (70%)
Frame = +3
Query: 600 AAAFSSVHQLREILMDETKGMYERYAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAY 779
A+ S VH L ++L+D K + R+ ALF LRN GG EA+ I +SALL+HE+AY
Sbjct: 3 ASLSSEVHSLGQLLIDPGKPLPLRFRALFTLRNLGGAEAIDCIGRGFQDESALLKHELAY 62
Query: 780 VLGQLQNKAALATPSKILRDLKEHPMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQ 959
LGQ++++ AL ++L+D ++ PMVRHEA EALG+I D + + LL+E+++DP V++
Sbjct: 63 CLGQMKDRRALPVLKQVLQDRQQEPMVRHEAGEALGAIGDPEVLELLREYAQDPVIEVAE 122
Query: 960 SCEVALSMLEF 992
+C++A+S +E+
Sbjct: 123 TCQLAVSRIEW 133
>sp|Q9V9U4|DOHH_DROME Deoxyhypusine hydroxylase OS=Drosophila melanogaster
GN=nero PE=2 SV=1
Length = 302
Score = 228 bits (581), Expect = 7e-059
Identities = 129/281 (45%), Positives = 176/281 (62%), Gaps = 8/281 (2%)
Frame = +3
Query: 159 LLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHESAFALGQMQDAEAVPA 338
L ++ +P+ ERFRALF+L+N+ G A A+ A D S LL HE A+ LGQMQDA+A+
Sbjct: 14 LNNKERPLKERFRALFTLKNIGGGAAIEAISKAFDDDSALLKHELAYCLGQMQDAQALDI 73
Query: 339 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKRIEEL 518
L VL D + P+VRHEAAEA+GAIG IL++ DP EV ETC +AL R+ L
Sbjct: 74 LTKVLKDTTQEPMVRHEAAEAMGAIGHPDVLPILEE-YKQDPVVEVAETCAIALDRVRWL 132
Query: 519 SSVVDAEKNQSDTTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFALRN 698
S + +P+ SVDP+ P A SV +L+ I +D + +++RY A+F+LRN
Sbjct: 133 QS-------GQKVDDSNPYASVDPSPPTAGDKSVTELKAIYLDAQQSLFDRYRAMFSLRN 185
Query: 699 HGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALATPSKILRDLKEHPMVRHEAAE 878
EE+V AI + L SAL RHEVA+VLGQLQ ++ + L D E+ MVRHE AE
Sbjct: 186 LRTEESVLAIAEGLKDSSALFRHEVAFVLGQLQEPCSIPFLQENLEDRLENEMVRHECAE 245
Query: 879 ALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENS 1001
ALG+IA E I +L ++ D + +V +SC +AL M E+ENS
Sbjct: 246 ALGAIATEDCIQILNRYAEDDKRVVKESCVIALDMCEYENS 286
>sp|Q297S2|DOHH_DROPS Deoxyhypusine hydroxylase OS=Drosophila pseudoobscura
pseudoobscura GN=nero PE=3 SV=1
Length = 302
Score = 226 bits (576), Expect = 3e-058
Identities = 128/281 (45%), Positives = 176/281 (62%), Gaps = 8/281 (2%)
Frame = +3
Query: 159 LLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHESAFALGQMQDAEAVPA 338
L ++ +P+ ERFRALF+L+N+ G +A+ A D S LL HE A+ LGQMQD A+
Sbjct: 14 LNNKDRPLKERFRALFTLKNIGGKTAIDAISKAFDDDSALLKHELAYCLGQMQDPTALEI 73
Query: 339 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKRIEEL 518
L VL D + P+VRHEAAEA+GAIG A IL++ DP EV ETC +AL R+ L
Sbjct: 74 LTKVLKDTTQEPMVRHEAAEAMGAIGHADVLAILEE-YKKDPVVEVAETCAIALDRVRWL 132
Query: 519 SSVVDAEKNQSDTTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFALRN 698
S + +P+ SVDP+ P A SV +L+ I +D + +++RY A+F+LRN
Sbjct: 133 QS-------GQQVADNNPYASVDPSPPTAGDKSVAELKAIYLDAKQTLFDRYRAMFSLRN 185
Query: 699 HGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALATPSKILRDLKEHPMVRHEAAE 878
EE+V AI + L SAL RHEVA+VLGQLQ ++ + L D KE+ MVRHE AE
Sbjct: 186 LCTEESVLAIAEGLKDSSALFRHEVAFVLGQLQEPCSIPYLQENLEDHKENEMVRHECAE 245
Query: 879 ALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENS 1001
ALG+IA + I +L ++ D + +V +SC +AL M E+ENS
Sbjct: 246 ALGAIATDDCIQILTRYADDEKRVVKESCVIALDMCEYENS 286
>sp|Q9P6K9|DOHH_SCHPO Deoxyhypusine hydroxylase OS=Schizosaccharomyces pombe
GN=lia1 PE=2 SV=1
Length = 318
Score = 214 bits (544), Expect = 1e-054
Identities = 127/310 (40%), Positives = 183/310 (59%), Gaps = 13/310 (4%)
Frame = +3
Query: 99 SASPTENGGVSKLEKFLCERLLDQSQPISERFRALFSLRNLKGPAPR---NALILASRDS 269
S+ P + +LE+ L LD+S P+S R+RALFSL L + +A+ A D
Sbjct: 2 SSEPVPQAVIDELERVLVN--LDKSNPLSFRYRALFSLNALAKKGDKRAVDAIYKAFIDD 59
Query: 270 SNLLAHESAFALGQMQDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKS 449
S LL HE A+ +GQ AV L +++ND+ +VRHEAAEALGA+G + +L+K
Sbjct: 60 SELLKHEMAYVMGQSGQQYAVQPLINIVNDLDQQVMVRHEAAEALGALGFTESLPVLEKY 119
Query: 450 LILDPAQEVRETCELALKRIEELSSVVDAEKNQSDTTERSPFMSVDPAAPAA-----AFS 614
DP +RETCELA+ RI+ + + +KN T VDPA P S
Sbjct: 120 YKEDPLAPIRETCELAIARIQWKNGL---DKNNEKITPSMYDSVVDPAPPMPDHEQDVKS 176
Query: 615 SVHQLREILMDETKGMYERYAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQL 794
V +LR ++D+ ++ RY +F LRN G EEAV A+ D S L RHE+A+V GQ+
Sbjct: 177 EVAKLRSEIVDQNLPLFYRYRVMFRLRNIGNEEAVLALTDGFKDPSPLFRHEIAFVFGQM 236
Query: 795 QNKAALATPSKILRDLKEHPMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVA 974
A++ K+L + +E PMVRHEAAEALG IA+++ + +L++FS+D +V++SC VA
Sbjct: 237 IAPASVPALIKVLENTEEVPMVRHEAAEALGGIANDECLPVLKKFSKDDVRVVAESCIVA 296
Query: 975 LSMLEFENSG 1004
L M+E+E SG
Sbjct: 297 LDMIEYEKSG 306
>sp|Q59Z14|DOHH_CANAL Deoxyhypusine hydroxylase OS=Candida albicans GN=LIA1 PE=3
SV=1
Length = 318
Score = 213 bits (541), Expect = 3e-054
Identities = 126/287 (43%), Positives = 178/287 (62%), Gaps = 15/287 (5%)
Frame = +3
Query: 180 ISERFRALFSLRNL------KGPAPRNALILAS--RDSSNLLAHESAFALGQMQDAEAVP 335
++ RFRALF+L+++ K A + +A D S LL HE A+ LGQ +D A P
Sbjct: 29 LANRFRALFNLKSVGSEDSDKERAHKAIKYIAECFNDDSELLKHEVAYVLGQTKDLYAAP 88
Query: 336 ALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKRIEE 515
L VL + + +VRHEAAEALGA+G + +L+K DP E+R+TCELA++RI
Sbjct: 89 YLREVLENDNQQCMVRHEAAEALGALGDKESLPLLEKYFKEDPLLEIRQTCELAIERIHW 148
Query: 516 LSSVVDAEKNQSDTTERSPFMSVDPAAPAA---AFSSVHQLREILMDETKGMYERYAALF 686
+S EK +++ E+S + S+DPA P A + S V +L+EIL D+ K ++ERY A+F
Sbjct: 149 ENS----EKAKNEVLEKSLYTSIDPAPPLATNDSTSKVEKLKEILNDQDKPLFERYRAMF 204
Query: 687 ALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALATPSKILRDLKEHPMVRH 866
LR+ G +EA A+ SAL +HE+AYV GQ+ N + + K+L+D E MVRH
Sbjct: 205 RLRDIGTDEACLALASGFDDPSALFKHEIAYVFGQMCNPVTVPSLIKVLKDESEAGMVRH 264
Query: 867 EAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGK 1007
EAAEALGSIA ++ + +LQ F D EP+V S VAL M E+ENS +
Sbjct: 265 EAAEALGSIATDECLPVLQSFLNDSEPVVRDSAIVALDMYEYENSNE 311
>sp|Q6CHJ7|DOHH_YARLI Deoxyhypusine hydroxylase OS=Yarrowia lipolytica GN=LIA1
PE=3 SV=1
Length = 308
Score = 210 bits (534), Expect = 2e-053
Identities = 119/291 (40%), Positives = 184/291 (63%), Gaps = 14/291 (4%)
Frame = +3
Query: 165 DQSQPISERFRALFSLRNLKGPAPRNALILAS---RDSSNLLAHESAFALGQMQDAEAVP 335
D ++ RFRALFSL+++ A+ + + +D S LL HE A+ LGQ ++ AV
Sbjct: 17 DGQTALALRFRALFSLKDMGEKGDNGAIDVIAEGFKDDSELLKHELAYVLGQTKNFHAVK 76
Query: 336 ALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKRIEE 515
L+ VL D + +VRHEAAEALGA+G G+ +L++ DP + +RETCELAL+RI+
Sbjct: 77 PLQGVLADTNQQAMVRHEAAEALGALGDKGSVAMLQEYFENDPLEVIRETCELALERIKW 136
Query: 516 LSSVVDAEKNQSDTTERSPFMSVDPAAP-------AAAFSSVHQLREILMDETKGMYERY 674
+S E +++T ++S + S+DPA P + ++V +L++ LMD+++ ++ RY
Sbjct: 137 ENS----EAAKTETLQKSAYTSIDPAPPLPTDQAEGSDKATVEKLQKTLMDKSQSLFHRY 192
Query: 675 AALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALATPSKILRDLKEHP 854
A+F LR+ G E+AV A+ SAL RHE+AYV GQ+ + A++ K+L +E
Sbjct: 193 RAMFRLRDIGTEDAVLALATGFDDSSALFRHEIAYVFGQMSDPASVPALIKVLGKTEEEG 252
Query: 855 MVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGK 1007
MVRHEAAEALGSIA + + +L++F+ D + +V +S VAL M E+ENS +
Sbjct: 253 MVRHEAAEALGSIATDDVLPILKKFAEDKDQVVRESAIVALDMYEYENSNE 303
>sp|Q6FUV3|DOHH_CANGA Deoxyhypusine hydroxylase OS=Candida glabrata GN=LIA1 PE=3
SV=1
Length = 322
Score = 198 bits (502), Expect = 1e-049
Identities = 118/287 (41%), Positives = 174/287 (60%), Gaps = 15/287 (5%)
Frame = +3
Query: 180 ISERFRALFSLRNLKGPAPRNALILASR---------DSSNLLAHESAFALGQMQDAEAV 332
++ RFRALF+L+ N D+S LL HE A+ LGQ ++ +A
Sbjct: 34 LANRFRALFNLKTAASEFEANPSDAEKAVQYMGETFGDNSELLKHEVAYVLGQTKNLKAA 93
Query: 333 PALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKRIE 512
P L + D++ P+VRHEAAEALGA+G + E L+K L DP VRETCELA+ RI
Sbjct: 94 PLLRKTMLDLAQQPMVRHEAAEALGALGDKDSLEDLEKCLKNDPHVAVRETCELAIARIN 153
Query: 513 ELSSVVDAEKNQSDTTERSPFMSVDPAAPAAAFS--SVHQLREILMDETKGMYERYAALF 686
S DA +S ++S + S+DPA P A + +L+++L D+ K ++ RY A+F
Sbjct: 154 WQHS--DAPTKES--LQQSLYSSIDPAPPLALEKEYDLEELKKLLNDQEKPLFLRYRAMF 209
Query: 687 ALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALATPSKILRDLKEHPMVRH 866
LR+ G +EAV A+ + SAL +HE+AYV GQ+ + AA+ + +++L +E PMVRH
Sbjct: 210 RLRDIGTDEAVLALASGFNDPSALFKHEIAYVFGQMGSTAAVPSLTEVLGRKEEAPMVRH 269
Query: 867 EAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGK 1007
EAAEALG+IA E ++ +L+++ D +V +S VAL M E+ENS +
Sbjct: 270 EAAEALGAIASEDALPILKQYLNDEVDVVRESAIVALDMWEYENSNE 316
>sp|Q6CV81|DOHH_KLULA Deoxyhypusine hydroxylase OS=Kluyveromyces lactis GN=LIA1
PE=3 SV=1
Length = 322
Score = 198 bits (501), Expect = 1e-049
Identities = 120/289 (41%), Positives = 171/289 (59%), Gaps = 21/289 (7%)
Frame = +3
Query: 177 PISERFRALFSLRNLKGPA------PRNA------LILASRDSSNLLAHESAFALGQMQD 320
P++ RFRALF NLKG A P +A L A D S LL HE A+ LGQ ++
Sbjct: 33 PLANRFRALF---NLKGHAEEFASKPEDALKATQYLAEAFGDESELLKHEVAYVLGQTKN 89
Query: 321 AEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELAL 500
P L VL D +VRHEAAEALGA+ + +IL+K DP E+R+TCELA+
Sbjct: 90 MAGAPLLRDVLADDKQQCMVRHEAAEALGALNDVDSLDILEKYFKEDPLLEIRQTCELAI 149
Query: 501 KRIEELSSVVDAEKNQSDTTERSPFMSVDPAAPAAAFS--SVHQLREILMDETKGMYERY 674
RI+ +S E+ + + + S + S+DPA P + + +L++IL D+ + ++ERY
Sbjct: 150 DRIKWETS----EEGRREALQESLYSSIDPAPPFSLEKDYKIQELKDILNDQNRPLFERY 205
Query: 675 AALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALATPSKILRDLKEHP 854
A+F LR+ G +EA A+ SAL +HE+AYV GQ+ N + ++L +E P
Sbjct: 206 RAMFRLRDIGNDEACLALASGFDDPSALFKHEIAYVFGQICNPVVVPHLKEVLARPEEAP 265
Query: 855 MVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENS 1001
MVRHEAAEALGSIA + + +L+E +D + +V +S VAL M E+ENS
Sbjct: 266 MVRHEAAEALGSIATDDVLPVLKEHLKDSDSVVRESAIVALDMYEYENS 314
>sp|P47120|DOHH_YEAST Deoxyhypusine hydroxylase OS=Saccharomyces cerevisiae
GN=LIA1 PE=1 SV=1
Length = 325
Score = 188 bits (477), Expect = 8e-047
Identities = 103/250 (41%), Positives = 158/250 (63%), Gaps = 6/250 (2%)
Frame = +3
Query: 264 DSSNLLAHESAFALGQMQDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILK 443
D S LL HE A+ LGQ ++ +A P L V+ D + P+VRHEAAEALGA+G + + L
Sbjct: 72 DKSELLKHEVAYVLGQTKNLDAAPTLRHVMLDQNQEPMVRHEAAEALGALGDKDSLDDLN 131
Query: 444 KSLILDPAQEVRETCELALKRIEELSSVVDAEKNQSDTTERSPFMSVDPA--APAAAFSS 617
K+ DP VRETCELA+ RI ++N ++S + S+DPA P ++
Sbjct: 132 KAAKEDPHVAVRETCELAINRINWTHGGAKDKEN----LQQSLYSSIDPAPPLPLEKDAT 187
Query: 618 VHQLREILMDETKGMYERYAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQ 797
+ +L+ +L D + +++RY A+F LR+ G +EA+ A+ SA+S+L +HE+AYV GQ+
Sbjct: 188 IPELQALLNDPKQPLFQRYRAMFRLRDIGTDEAILALATGFSAESSLFKHEIAYVFGQIG 247
Query: 798 NKAALATPSKILRDLKEHPMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVAL 977
+ AA+ + ++L +E PMVRHEAAEALG+IA + + +L+ + D +V +SC VAL
Sbjct: 248 SPAAVPSLIEVLGRKEEAPMVRHEAAEALGAIASPEVVDVLKSYLNDEVDVVRESCIVAL 307
Query: 978 SMLEFENSGK 1007
M ++ENS +
Sbjct: 308 DMYDYENSNE 317
>sp|Q17949|DOHH_CAEEL Deoxyhypusine hydroxylase OS=Caenorhabditis elegans
GN=tag-242 PE=3 SV=1
Length = 298
Score = 115 bits (287), Expect = 8e-025
Identities = 62/133 (46%), Positives = 89/133 (66%), Gaps = 1/133 (0%)
Frame = +3
Query: 612 SSVHQLREILMDETKGMYERYAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQ 791
+ + E L D K + R+ ALF LRN G + +V I L+ +SALL+HE+AY LGQ
Sbjct: 10 AEIDSFGEALNDTKKPLKARFRALFILRNIGCDRSVDWIGKCLNDESALLKHELAYCLGQ 69
Query: 792 LQNKAALATPSKILRDLKEHPMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEV 971
+QNK A+ T +L D K+ PMVRHEA EALG+IAD +L+++++DP P VS++C++
Sbjct: 70 MQNKHAIPTLVSVLEDEKQEPMVRHEAGEALGAIADPSVKDVLRKYAQDPCPEVSETCQI 129
Query: 972 ALSMLEF-ENSGK 1007
AL +E+ E SGK
Sbjct: 130 ALGRVEWVEKSGK 142
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106,282,147,502
Number of Sequences: 518415
Number of Extensions: 106282147502
Number of Successful Extensions: 672117376
Number of sequences better than 0.0: 0
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