BLASTX 7.6.2
Query= UN25938 /QuerySize=943
(942 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q0WTY4|VPS2B_ARATH Vacuolar protein sorting-associated protei... 399 2e-110
sp|Q941D5|VPS2C_ARATH Vacuolar protein sorting-associated protei... 279 2e-074
sp|Q9SKI2|VPS2A_ARATH Vacuolar protein sorting-associated protei... 174 7e-043
sp|Q54DB1|CM2A2_DICDI Charged multivesicular body protein 2a hom... 152 5e-036
sp|Q6NXD2|CHM2B_DANRE Charged multivesicular body protein 2b OS=... 150 1e-035
sp|Q7ZW25|CHM2A_DANRE Charged multivesicular body protein 2a OS=... 146 3e-034
sp|Q66IV6|CH2BB_XENLA Charged multivesicular body protein 2b-B O... 145 5e-034
sp|O43633|CHM2A_HUMAN Charged multivesicular body protein 2a OS=... 145 5e-034
sp|Q9DB34|CHM2A_MOUSE Charged multivesicular body protein 2a OS=... 145 5e-034
sp|Q6DFS6|CHM2A_XENTR Charged multivesicular body protein 2a OS=... 145 6e-034
sp|Q5F3A2|CHM2B_CHICK Charged multivesicular body protein 2b OS=... 144 1e-033
sp|Q7SYR0|CH2BA_XENLA Charged multivesicular body protein 2b-A O... 144 1e-033
sp|Q6IP52|CHM2A_XENLA Charged multivesicular body protein 2a OS=... 143 2e-033
sp|Q6NVL7|CHM2B_XENTR Charged multivesicular body protein 2b OS=... 143 3e-033
sp|Q3SX42|CHM2B_BOVIN Charged multivesicular body protein 2b OS=... 141 9e-033
sp|Q9UQN3|CHM2B_HUMAN Charged multivesicular body protein 2b OS=... 141 9e-033
sp|Q5RAV2|CHM2B_PONAB Charged multivesicular body protein 2b OS=... 141 9e-033
sp|Q8BJF9|CHM2B_MOUSE Charged multivesicular body protein 2b OS=... 140 2e-032
sp|Q5ZHN1|CHM2A_CHICK Charged multivesicular body protein 2a OS=... 138 7e-032
sp|P36108|DID4_YEAST DOA4-independent degradation protein 4 OS=S... 134 1e-030
>sp|Q0WTY4|VPS2B_ARATH Vacuolar protein sorting-associated protein 2 homolog 2
OS=Arabidopsis thaliana GN=VPS2.2 PE=2 SV=2
Length = 222
Score = 399 bits (1024), Expect = 2e-110
Identities = 214/223 (95%), Positives = 220/223 (98%), Gaps = 1/223 (0%)
Frame = +3
Query: 132 MNIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKI 311
MNIF+KKTTPKDALRTSKREM+VATRGIEREI+SLQ+EEKRLVAEIKKTAKTGNEAATKI
Sbjct: 1 MNIFKKKTTPKDALRTSKREMAVATRGIEREITSLQLEEKRLVAEIKKTAKTGNEAATKI 60
Query: 312 LARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTK 491
LARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTK
Sbjct: 61 LARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTK 120
Query: 492 QAKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSS 671
QAKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSS
Sbjct: 121 QAKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSS 180
Query: 672 APKGRIATKTAAPPATTANSNSNSSESSEVDELEKRLASLRRI 800
APKGRIATKTAAPPA+TA +N N SESSEVDELEKRLASLRRI
Sbjct: 181 APKGRIATKTAAPPASTAATNKN-SESSEVDELEKRLASLRRI 222
>sp|Q941D5|VPS2C_ARATH Vacuolar protein sorting-associated protein 2 homolog 3
OS=Arabidopsis thaliana GN=VPS2.3 PE=2 SV=1
Length = 210
Score = 279 bits (713), Expect = 2e-074
Identities = 139/191 (72%), Positives = 167/191 (87%)
Frame = +3
Query: 132 MNIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKI 311
MNIF KK P++ LR SKREM+ ATRGIE+EI SLQ EEK+LV EIK+TAK+GNE ATKI
Sbjct: 1 MNIFTKKPNPREVLRESKREMTQATRGIEKEIGSLQSEEKKLVLEIKRTAKSGNEGATKI 60
Query: 312 LARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTK 491
LARQL+RLRQQI NLQGSRAQ+RG+ THTQA++A TS+++GM+GATKAM AM+K M P K
Sbjct: 61 LARQLIRLRQQIANLQGSRAQMRGIATHTQAMHAHTSVAAGMQGATKAMAAMSKNMDPAK 120
Query: 492 QAKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSS 671
QAKV+++FQKQSAQ+DMT EMMS++ID+ LD DEAE+ETEDLTNQVLDEIG+ +ASQLSS
Sbjct: 121 QAKVMREFQKQSAQMDMTTEMMSDSIDDALDNDEAEDETEDLTNQVLDEIGIDIASQLSS 180
Query: 672 APKGRIATKTA 704
APKG+I K A
Sbjct: 181 APKGKIGGKKA 191
>sp|Q9SKI2|VPS2A_ARATH Vacuolar protein sorting-associated protein 2 homolog 1
OS=Arabidopsis thaliana GN=VPS2.1 PE=2 SV=2
Length = 225
Score = 174 bits (441), Expect = 7e-043
Identities = 89/222 (40%), Positives = 138/222 (62%)
Frame = +3
Query: 135 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 314
+IF K+ TP + LR +KR + + R IERE LQ +EK+L+ EIKKTAK G A K++
Sbjct: 4 SIFGKRKTPAELLRENKRMLDKSIREIERERQGLQTQEKKLINEIKKTAKQGQMGAVKVM 63
Query: 315 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 494
A+ L+R R QI ++Q++GV+ Q L ++ ++ MKG TKAM MN+QM
Sbjct: 64 AKDLIRTRHQIEKFYKLKSQLQGVSLRIQTLKSTQAMGEAMKGVTKAMGQMNRQMNLPSL 123
Query: 495 AKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 674
K++++F++Q+ +++M E+M +AID+ L+ DE EEETEDL +QVLDEIG+ + +L +A
Sbjct: 124 QKIMQEFERQNEKMEMVSEVMGDAIDDALEGDEEEEETEDLVSQVLDEIGIDINQELVNA 183
Query: 675 PKGRIATKTAAPPATTANSNSNSSESSEVDELEKRLASLRRI 800
P G +A A A + +L+ RL +LR++
Sbjct: 184 PSGAVAVPAAKNKVVQAEATGAEDSGGIDSDLQARLDNLRKM 225
>sp|Q54DB1|CM2A2_DICDI Charged multivesicular body protein 2a homolog 2
OS=Dictyostelium discoideum GN=chmp2a2 PE=3 SV=1
Length = 198
Score = 152 bits (382), Expect = 5e-036
Identities = 73/182 (40%), Positives = 124/182 (68%)
Frame = +3
Query: 132 MNIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKI 311
M +F K+ TPK+ LR ++R ++ + R I+RE +LQ +EK+++ +IKK AK G + KI
Sbjct: 1 MFLFGKQKTPKEVLRENQRNLNKSMREIDRERVALQNQEKKIILDIKKMAKQGQMNSAKI 60
Query: 312 LARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTK 491
+A+ LVR R I + Q++ V+ Q L ++ +++ MKG TKAM+ MN+QM +
Sbjct: 61 MAKDLVRTRYHIQKFYEMKTQLQAVSLRIQTLQSTQAMAEAMKGVTKAMITMNRQMNLPQ 120
Query: 492 QAKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSS 671
K++ +F++QS ++DM EMM++ +D+ +++D EE+++++ NQVLDEIG+ +ASQL
Sbjct: 121 FTKIMMEFEQQSDKMDMKEEMMNDTMDQVMEQDGEEEQSQEILNQVLDEIGIDLASQLVD 180
Query: 672 AP 677
AP
Sbjct: 181 AP 182
>sp|Q6NXD2|CHM2B_DANRE Charged multivesicular body protein 2b OS=Danio rerio
GN=chmp2b PE=2 SV=1
Length = 214
Score = 150 bits (378), Expect = 1e-035
Identities = 80/208 (38%), Positives = 133/208 (63%), Gaps = 5/208 (2%)
Frame = +3
Query: 135 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 314
++F+KKT D ++ +E+ R I R+ ++L+ +EK+L EIKK AKTGN A K+L
Sbjct: 3 SLFKKKTV-DDVIKEQNKELRGTQRQIARDRTALEKQEKQLEMEIKKMAKTGNRDACKVL 61
Query: 315 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 494
A+QLV++R+Q T +++ ++T T+ + + ++ M TK M A+NK+M P K
Sbjct: 62 AKQLVQVRKQKTRTYAVSSKVTSMSTQTKLMNSQMKMAGAMATTTKTMQAVNKKMDPKKT 121
Query: 495 AKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 674
+ +++FQK++A++DMT EMM++ +DE + EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 MQTLQNFQKETAKMDMTEEMMNDTLDEIFEDSGDEEESQDIVNQVLDEIGIEISGKMAHA 181
Query: 675 PKGRIATKTAAPPATTANSNSNSSESSE 758
P A KT P A TA ++ S E E
Sbjct: 182 PSA--ARKT--PSAATAKADGISDEDIE 205
>sp|Q7ZW25|CHM2A_DANRE Charged multivesicular body protein 2a OS=Danio rerio
GN=chmp2a PE=2 SV=1
Length = 220
Score = 146 bits (367), Expect = 3e-034
Identities = 76/210 (36%), Positives = 134/210 (63%), Gaps = 5/210 (2%)
Frame = +3
Query: 135 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 314
++F ++ TP++ LR ++R ++ A R ++RE L+ +EK+++A+IKK AK G A KI+
Sbjct: 3 SLFGRRKTPEEMLRQNQRALNRAMRDLDRERQRLEQQEKKIIADIKKMAKQGQMDAVKIM 62
Query: 315 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 494
A+ LVR R+ + RA I+ V+ Q L ++ S++ MKG TKAM MN+Q+ +
Sbjct: 63 AKDLVRTRRYVKKFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQI 122
Query: 495 AKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 674
K++ +F++QS +DM EMM++AID+ + ++ EEE++ + +QVLDE+G+ ++ +LS+
Sbjct: 123 QKIMMEFERQSEIMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLSDELSNL 182
Query: 675 PK-----GRIATKTAAPPATTANSNSNSSE 749
P A K A P T A+++++ E
Sbjct: 183 PATGGSLSVAAGKKAEPQPTLADADADLEE 212
>sp|Q66IV6|CH2BB_XENLA Charged multivesicular body protein 2b-B OS=Xenopus
laevis GN=chmp2b-b PE=2 SV=1
Length = 214
Score = 145 bits (365), Expect = 5e-034
Identities = 74/208 (35%), Positives = 129/208 (62%), Gaps = 5/208 (2%)
Frame = +3
Query: 135 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 314
++F+KKT D +R +E+ R I R+ ++L+ +EK+L EIKK AKTGN+ A ++L
Sbjct: 3 SLFKKKTV-DDIIREQNKELRGTQRAITRDRAALEKQEKQLEMEIKKMAKTGNKDACRVL 61
Query: 315 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 494
A+QLV+LR+Q T +++ ++T T+ + + ++ M K M A+NK+M P K
Sbjct: 62 AKQLVQLRKQKTRTYAVSSKVTSMSTQTKVMSSQMKMAGAMSTTAKTMQAVNKKMDPQKT 121
Query: 495 AKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 674
+ +++FQK++ +++MT EM+++ +D+ D E EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 LQTMQNFQKENMKMEMTDEMINDTLDDIFDASEDEEESQDIVNQVLDEIGIEISGKMAKA 181
Query: 675 PKGRIATKTAAPPATTANSNSNSSESSE 758
P + P + A S S E E
Sbjct: 182 P----SAAKGLPSTSAAKSKGISDEEIE 205
>sp|O43633|CHM2A_HUMAN Charged multivesicular body protein 2a OS=Homo sapiens
GN=CHMP2A PE=1 SV=1
Length = 222
Score = 145 bits (365), Expect = 5e-034
Identities = 78/221 (35%), Positives = 138/221 (62%), Gaps = 6/221 (2%)
Frame = +3
Query: 138 IFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKILA 317
+F ++ TP++ LR ++R ++ A R ++RE L+ +EK+++A+IKK AK G A +I+A
Sbjct: 4 LFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMA 63
Query: 318 RQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQA 497
+ LVR R+ + RA I+ V+ Q L ++ S++ MKG TKAM MN+Q+ +
Sbjct: 64 KDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQ 123
Query: 498 KVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSAP 677
K++ +F++Q+ +DM EMM++AID+ + +E EEE++ + +QVLDE+G+ + +LS+ P
Sbjct: 124 KIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLP 183
Query: 678 K--GRIATKTAAPPATTANSNSNSSESSEVDELEKRLASLR 794
G ++ A A S +++ +LE+RL +LR
Sbjct: 184 STGGSLSVAAGGKKAEAAASALADADA----DLEERLKNLR 220
>sp|Q9DB34|CHM2A_MOUSE Charged multivesicular body protein 2a OS=Mus musculus
GN=Chmp2a PE=1 SV=1
Length = 222
Score = 145 bits (365), Expect = 5e-034
Identities = 78/219 (35%), Positives = 139/219 (63%), Gaps = 2/219 (0%)
Frame = +3
Query: 138 IFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKILA 317
+F ++ TP++ LR ++R ++ A R ++RE L+ +EK+++A+IKK AK G A +I+A
Sbjct: 4 LFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMA 63
Query: 318 RQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQA 497
+ LVR R+ + RA I+ V+ Q L ++ S++ MKG TKAM MN+Q+ +
Sbjct: 64 KDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQ 123
Query: 498 KVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSAP 677
K++ +F++Q+ +DM EMM++AID+ + +E EEE++ + +QVLDE+G+ + +LS+ P
Sbjct: 124 KIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLP 183
Query: 678 KGRIATKTAAPPATTANSNSNSSESSEVDELEKRLASLR 794
+ AA A + +++ ++ D LE+RL +LR
Sbjct: 184 STGGSLSVAA-GGKKAEATASALADADAD-LEERLKNLR 220
>sp|Q6DFS6|CHM2A_XENTR Charged multivesicular body protein 2a OS=Xenopus
tropicalis GN=chmp2a PE=2 SV=1
Length = 220
Score = 145 bits (364), Expect = 6e-034
Identities = 76/209 (36%), Positives = 133/209 (63%), Gaps = 5/209 (2%)
Frame = +3
Query: 138 IFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKILA 317
+F ++ TP++ LR ++R ++ A R ++RE L+ +EK+++A+IKK AK G A KI+A
Sbjct: 4 LFGRRKTPEEMLRQNQRALNKAMREMDRERQKLEQQEKKIIADIKKMAKQGQMDAVKIMA 63
Query: 318 RQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQA 497
+ LVR R+ + RA I+ V+ Q L ++ S++ MKG TKAM MN+Q+ +
Sbjct: 64 KDLVRTRRYVKKFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQIQ 123
Query: 498 KVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSAP 677
K++ +F+KQS +DM EMM++AID+ + ++ EEE++ + +QVLDE+G+ + +LS+ P
Sbjct: 124 KIMMEFEKQSEIMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLTDELSNLP 183
Query: 678 K--GRIA---TKTAAPPATTANSNSNSSE 749
G ++ K P A A+++++ E
Sbjct: 184 STGGSLSVAGAKKGEPSAALADADADLEE 212
>sp|Q5F3A2|CHM2B_CHICK Charged multivesicular body protein 2b OS=Gallus gallus
GN=CHMP2B PE=2 SV=1
Length = 214
Score = 144 bits (362), Expect = 1e-033
Identities = 72/208 (34%), Positives = 132/208 (63%), Gaps = 5/208 (2%)
Frame = +3
Query: 135 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 314
++F+KKT D ++ RE+ R I R+ ++L+ +E++L EIKK AKTGN+ A K+L
Sbjct: 3 SLFKKKTV-DDIIKEQNRELRGTQRTITRDRAALEKQERQLELEIKKMAKTGNKEACKVL 61
Query: 315 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 494
A+QLV+LR+Q +++ ++T T+ + + ++ M K M A+NK+M P K
Sbjct: 62 AKQLVQLRKQKNRTYAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKT 121
Query: 495 AKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 674
+ +++FQK++ +++MT EM+++ +D+ D + EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 LQTMQNFQKENMKMEMTEEMINDTLDDIFDASDEEEESQDIVNQVLDEIGIEISGKMAKA 181
Query: 675 PKGRIATKTAAPPATTANSNSNSSESSE 758
P + P A+T+ +++ S E E
Sbjct: 182 P----SAARGLPSASTSKASTISDEEIE 205
>sp|Q7SYR0|CH2BA_XENLA Charged multivesicular body protein 2b-A OS=Xenopus
laevis GN=chmp2b-a PE=2 SV=1
Length = 214
Score = 144 bits (361), Expect = 1e-033
Identities = 73/208 (35%), Positives = 129/208 (62%), Gaps = 5/208 (2%)
Frame = +3
Query: 135 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 314
++F+KKT D ++ +E+ R I R+ ++L+ +EK+L EIKK AK GN+ A K+L
Sbjct: 3 SLFKKKTV-DDIIKDQNKELKGQQRAITRDRTALEKQEKQLEMEIKKMAKAGNKDACKVL 61
Query: 315 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 494
A+QLV+LR+Q T +++ ++T T+ + + ++ M K M A+NK+M P K
Sbjct: 62 AKQLVQLRKQKTRTYAVSSKVTSMSTQTKVMSSQMKMAGAMSTTAKTMQAVNKKMDPQKT 121
Query: 495 AKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 674
+ +++FQK++ +++MT EM+++ +D+ D E EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 LQTMQNFQKENMKMEMTEEMINDTLDDIFDASEDEEESQDIVNQVLDEIGIEISGKMAKA 181
Query: 675 PKGRIATKTAAPPATTANSNSNSSESSE 758
P + P A+ + S S E E
Sbjct: 182 P----SAAKGLPSASASKSTGISDEEIE 205
>sp|Q6IP52|CHM2A_XENLA Charged multivesicular body protein 2a OS=Xenopus laevis
GN=chmp2a PE=2 SV=1
Length = 220
Score = 143 bits (360), Expect = 2e-033
Identities = 76/215 (35%), Positives = 134/215 (62%), Gaps = 4/215 (1%)
Frame = +3
Query: 138 IFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKILA 317
+F ++ TP++ LR ++R ++ A R ++RE L+ +EK+++A+IKK AK G A KI+A
Sbjct: 4 LFGRRKTPEELLRQNQRALNRAMRELDRERQKLEQQEKKIIADIKKMAKQGQMDAVKIMA 63
Query: 318 RQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQA 497
+ LVR R+ + RA I+ V+ Q L ++ S++ MKG TKAM MN+Q+ +
Sbjct: 64 KDLVRTRRYVKKFIMMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMATMNRQLKLPQIQ 123
Query: 498 KVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSAP 677
K++ +F+KQS +DM EMM++AID+ + ++ EEE++ + +QVLDE+G+ + +LS+ P
Sbjct: 124 KIMMEFEKQSEIMDMKEEMMNDAIDDAMGDEDDEEESDAVVSQVLDELGLTLTDELSNLP 183
Query: 678 KGRIATKTAAPPATTANSNSNSSESSEVDELEKRL 782
+T + A + ++ + +LE+RL
Sbjct: 184 ----STGGSLSVAGAKKGEATAALADADADLEERL 214
>sp|Q6NVL7|CHM2B_XENTR Charged multivesicular body protein 2b OS=Xenopus
tropicalis GN=chmp2b PE=2 SV=1
Length = 214
Score = 143 bits (358), Expect = 3e-033
Identities = 71/205 (34%), Positives = 131/205 (63%), Gaps = 6/205 (2%)
Frame = +3
Query: 135 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 314
++F+KKT D +R +E+ R I R+ ++L+ +EK+L EIKK AK GN+ A ++L
Sbjct: 3 SLFKKKTV-DDIIREQNKELRGTQRAITRDRAALEKQEKQLEMEIKKMAKAGNKDACRVL 61
Query: 315 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 494
A+QLV+LR+Q T +++ ++T T+ + + ++ M K M A+NK+M P K
Sbjct: 62 AKQLVQLRKQKTRTYAVSSKVTSMSTQTKVMSSQMKMAGAMSTTAKTMQAVNKKMDPQKT 121
Query: 495 AKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 674
+ +++FQK++ +++MT EM+++ +D+ D + EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 LQTMQNFQKENMKMEMTEEMINDTLDDIFDASDDEEESQDIVNQVLDEIGIEISGKMAKA 181
Query: 675 PKGRIATKTAAPPATTANSNSNSSE 749
P + P+T+A+ +S S+
Sbjct: 182 P-----SAAKGLPSTSASKSSGISD 201
>sp|Q3SX42|CHM2B_BOVIN Charged multivesicular body protein 2b OS=Bos taurus
GN=CHMP2B PE=2 SV=1
Length = 213
Score = 141 bits (354), Expect = 9e-033
Identities = 71/205 (34%), Positives = 129/205 (62%), Gaps = 5/205 (2%)
Frame = +3
Query: 135 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 314
++F+KKT D ++ RE+ R I R+ ++L+ +EK+L EIKK AK GN+ A ++L
Sbjct: 3 SLFKKKTV-DDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACRVL 61
Query: 315 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 494
A+QLV LR+Q T +++ ++T T+ + + ++ M K M A+NK+M P K
Sbjct: 62 AKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKT 121
Query: 495 AKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 674
+ +++FQK++ +++MT EM+++ +D+ D + EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 LQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKA 181
Query: 675 PKGRIATKTAAPPATTANSNSNSSE 749
P + + P A+T+ S + E
Sbjct: 182 P----SAARSLPSASTSKSTISDEE 202
>sp|Q9UQN3|CHM2B_HUMAN Charged multivesicular body protein 2b OS=Homo sapiens
GN=CHMP2B PE=1 SV=1
Length = 213
Score = 141 bits (354), Expect = 9e-033
Identities = 71/205 (34%), Positives = 129/205 (62%), Gaps = 5/205 (2%)
Frame = +3
Query: 135 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 314
++F+KKT D ++ RE+ R I R+ ++L+ +EK+L EIKK AK GN+ A K+L
Sbjct: 3 SLFKKKTV-DDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVL 61
Query: 315 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 494
A+QLV LR+Q T +++ ++T T+ + + ++ M K M A+NK+M P K
Sbjct: 62 AKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKT 121
Query: 495 AKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 674
+ +++FQK++ +++MT EM+++ +D+ D + EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 LQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKA 181
Query: 675 PKGRIATKTAAPPATTANSNSNSSE 749
P + + P A+T+ + + E
Sbjct: 182 P----SAARSLPSASTSKATISDEE 202
>sp|Q5RAV2|CHM2B_PONAB Charged multivesicular body protein 2b OS=Pongo abelii
GN=CHMP2B PE=2 SV=1
Length = 213
Score = 141 bits (354), Expect = 9e-033
Identities = 71/205 (34%), Positives = 129/205 (62%), Gaps = 5/205 (2%)
Frame = +3
Query: 135 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 314
++F+KKT D ++ RE+ R I R+ ++L+ +EK+L EIKK AK GN+ A K+L
Sbjct: 3 SLFKKKTV-DDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACKVL 61
Query: 315 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 494
A+QLV LR+Q T +++ ++T T+ + + ++ M K M A+NK+M P K
Sbjct: 62 AKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKT 121
Query: 495 AKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 674
+ +++FQK++ +++MT EM+++ +D+ D + EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 LQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKA 181
Query: 675 PKGRIATKTAAPPATTANSNSNSSE 749
P + + P A+T+ + + E
Sbjct: 182 P----SAARSLPSASTSKATISDEE 202
>sp|Q8BJF9|CHM2B_MOUSE Charged multivesicular body protein 2b OS=Mus musculus
GN=Chmp2b PE=2 SV=1
Length = 213
Score = 140 bits (351), Expect = 2e-032
Identities = 70/205 (34%), Positives = 129/205 (62%), Gaps = 5/205 (2%)
Frame = +3
Query: 135 NIFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKIL 314
++F+KKT D ++ RE+ R I R+ ++L+ +EK+L EIKK AK GN+ A ++L
Sbjct: 3 SLFKKKTV-DDVIKEQNRELRGTQRAIIRDRAALEKQEKQLELEIKKMAKIGNKEACRVL 61
Query: 315 ARQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQ 494
A+QLV LR+Q T +++ ++T T+ + + ++ M K M A+NK+M P K
Sbjct: 62 AKQLVHLRKQKTRTFAVSSKVTSMSTQTKVMNSQMKMAGAMSTTAKTMQAVNKKMDPQKT 121
Query: 495 AKVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSA 674
+ +++FQK++ +++MT EM+++ +D+ D + EEE++D+ NQVLDEIG+ ++ +++ A
Sbjct: 122 LQTMQNFQKENMKMEMTEEMINDTLDDIFDGSDDEEESQDIVNQVLDEIGIEISGKMAKA 181
Query: 675 PKGRIATKTAAPPATTANSNSNSSE 749
P + + P A+T+ + + E
Sbjct: 182 P----SAARSLPSASTSKATISDEE 202
>sp|Q5ZHN1|CHM2A_CHICK Charged multivesicular body protein 2a OS=Gallus gallus
GN=CHMP2A PE=2 SV=1
Length = 220
Score = 138 bits (346), Expect = 7e-032
Identities = 71/209 (33%), Positives = 132/209 (63%), Gaps = 5/209 (2%)
Frame = +3
Query: 138 IFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKILA 317
+F ++ TP++ LR ++R ++ A R ++RE L+ +EK+++ +IKK AK G A KI+A
Sbjct: 4 LFGRRKTPEELLRQNQRALTRAMRELDRERQKLEAQEKKIIIDIKKMAKQGQMDAVKIMA 63
Query: 318 RQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQA 497
+ LVR R+ + RA ++ V+ Q L ++ S++ MKG TKAM MN+Q+ +
Sbjct: 64 KDLVRTRRYVKKFITMRANVQAVSLKIQTLKSNNSMALAMKGVTKAMATMNRQLKLPQIQ 123
Query: 498 KVIKDFQKQSAQLDMTIEMMSEAIDETLDKDEAEEETEDLTNQVLDEIGVGVASQLSSAP 677
K++ +F+KQ+ +DM E+M++AID+ + ++ EEE++ + +QVLDE+G+ + +L++ P
Sbjct: 124 KIMMEFEKQAGIMDMKEELMNDAIDDAMGDEDDEEESDAVVSQVLDELGLNLTDELATLP 183
Query: 678 K--GRIAT---KTAAPPATTANSNSNSSE 749
G +A + A A A+++++ E
Sbjct: 184 PPGGSLAAGEGRAAEAAAALADADADLEE 212
>sp|P36108|DID4_YEAST DOA4-independent degradation protein 4 OS=Saccharomyces
cerevisiae GN=DID4 PE=1 SV=2
Length = 232
Score = 134 bits (335), Expect = 1e-030
Identities = 77/227 (33%), Positives = 130/227 (57%), Gaps = 10/227 (4%)
Frame = +3
Query: 138 IFRKKTTPKDALRTSKREMSVATRGIEREISSLQMEEKRLVAEIKKTAKTGNEAATKILA 317
+F K TP++ L+ ++R + R +ERE L++++K+LV+EIKK+AK G AA K+ A
Sbjct: 7 VFGKNVTPQERLKKNQRALERTQRELEREKRKLELQDKKLVSEIKKSAKNGQVAAAKVQA 66
Query: 318 RQLVRLRQQITNLQGSRAQIRGVTTHTQALYASTSISSGMKGATKAMVAMNKQMAPTKQA 497
+ LVR R I +AQ++ ++ QA+ +S ++ M AT + MN+ M +
Sbjct: 67 KDLVRTRNYIQKFDNMKAQLQAISLRIQAVRSSDQMTRSMSEATGLLAGMNRTMNLPQLQ 126
Query: 498 KVIKDFQKQSAQLDMTIEMMSEAIDETL-DKDEAEEETEDLTNQVLDEIGVGVASQLSSA 674
++ +F+KQS + E M EAID + D+ + +EE +++ N+VLDEIGV + SQL S
Sbjct: 127 RISMEFEKQSDLMGQRQEFMDEAIDNVMGDEVDEDEEADEIVNKVLDEIGVDLNSQLQST 186
Query: 675 PKGRIATKTAAPPATTAN------SNSNSSESSEVDELEKRLASLRR 797
P+ ++ AP A TA + + D+L+ RL +L++
Sbjct: 187 PQNLVSN---APIAETAMGIPEPIGAGSEFHGNPDDDLQARLNTLKK 230
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106,807,929,624
Number of Sequences: 518415
Number of Extensions: 106807929624
Number of Successful Extensions: 680323231
Number of sequences better than 0.0: 0
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