BLASTX 7.6.2
Query= UN25970 /QuerySize=818
(817 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P49592|NC2B_ARATH Protein Dr1 homolog OS=Arabidopsis thaliana... 282 3e-075
sp|Q55DJ5|NC2B_DICDI Protein Dr1 homolog OS=Dictyostelium discoi... 140 2e-032
sp|Q5ZMV3|NC2B_CHICK Protein Dr1 OS=Gallus gallus GN=DR1 PE=2 SV=1 121 8e-027
sp|Q01658|NC2B_HUMAN Protein Dr1 OS=Homo sapiens GN=DR1 PE=1 SV=1 121 8e-027
sp|Q91WV0|NC2B_MOUSE Protein Dr1 OS=Mus musculus GN=Dr1 PE=2 SV=1 121 8e-027
sp|Q5XI68|NC2B_RAT Protein Dr1 OS=Rattus norvegicus GN=Dr1 PE=2 ... 121 8e-027
sp|O14348|NC2B_SCHPO Negative cofactor 2 complex subunit beta OS... 118 6e-026
sp|Q9VJQ5|NC2B_DROME Protein Dr1 OS=Drosophila melanogaster GN=N... 107 9e-023
sp|Q92317|NCB2_YEAST Negative cofactor 2 complex subunit beta OS... 89 3e-017
sp|Q642A5|DPOE3_RAT DNA polymerase epsilon subunit 3 OS=Rattus n... 55 4e-007
sp|Q9JKP7|DPOE3_MOUSE DNA polymerase epsilon subunit 3 OS=Mus mu... 54 1e-006
sp|Q3SZN5|DPOE3_BOVIN DNA polymerase epsilon subunit 3 OS=Bos ta... 54 1e-006
sp|Q9NRF9|DPOE3_HUMAN DNA polymerase epsilon subunit 3 OS=Homo s... 54 1e-006
sp|Q5R4W3|DPOE3_PONAB DNA polymerase epsilon subunit 3 OS=Pongo ... 54 1e-006
>sp|P49592|NC2B_ARATH Protein Dr1 homolog OS=Arabidopsis thaliana GN=DR1 PE=2
SV=1
Length = 159
Score = 282 bits (719), Expect = 3e-075
Identities = 139/151 (92%), Positives = 146/151 (96%)
Frame = +2
Query: 101 MDPMDIVGKSKEDASLPKATMTKIIKEMLPADVRVARDAQDLLIECCVEFINLISSESNE 280
MDPMDIVGKSKEDASLPKATMTKIIKEMLP DVRVARDAQDLLIECCVEFINL+SSESN+
Sbjct: 1 MDPMDIVGKSKEDASLPKATMTKIIKEMLPPDVRVARDAQDLLIECCVEFINLVSSESND 60
Query: 281 VCNKEDKRTIAPEHVLKALQVLGFGEYVEEVYAAYEQHKYETMQDSQRSVKMNSGAEMTE 460
VCNKEDKRTIAPEHVLKALQVLGFGEY+EEVYAAYEQHKYETMQD+QRSVK N GA+MTE
Sbjct: 61 VCNKEDKRTIAPEHVLKALQVLGFGEYIEEVYAAYEQHKYETMQDTQRSVKWNPGAQMTE 120
Query: 461 EEAAAEQQRMFAEARARMNGGVSVPQPDQEQ 553
EEAAAEQQRMFAEARARMNGGVSVPQP+ +
Sbjct: 121 EEAAAEQQRMFAEARARMNGGVSVPQPEHPE 151
>sp|Q55DJ5|NC2B_DICDI Protein Dr1 homolog OS=Dictyostelium discoideum GN=dr1
PE=3 SV=1
Length = 178
Score = 140 bits (351), Expect = 2e-032
Identities = 72/154 (46%), Positives = 103/154 (66%), Gaps = 2/154 (1%)
Frame = +2
Query: 131 KEDASLPKATMTKIIKEMLPADVRVARDAQDLLIECCVEFINLISSESNEVCNKEDKRTI 310
+++ SLPKAT++K+IKEMLP DV+ + + +DL++ECCVEFI+LISSE+N++C +E KRTI
Sbjct: 8 EDNLSLPKATVSKLIKEMLPQDVKCSNETRDLILECCVEFIHLISSEANDICGREQKRTI 67
Query: 311 APEHVLKALQVLGFGEYVEEVYAAYEQHKYETMQDSQRSVKMNSGAEMTEEEAAAEQQRM 490
A EHV+KAL LGF +Y ++V Y++HK E S+ S K + + T E+ EQQ +
Sbjct: 68 AAEHVIKALTELGFSDYTQKVSDVYDKHKLEVSTKSKSSKKFENLGKPT-EQLIREQQLL 126
Query: 491 FAEARARMNGGVSVPQPDQEQQVDDNTQQSNLQS 592
FA+AR+ Q Q QQ QQ LQ+
Sbjct: 127 FAKARSAFQASPEAQQLQQLQQ-QQQQQQGGLQA 159
>sp|Q5ZMV3|NC2B_CHICK Protein Dr1 OS=Gallus gallus GN=DR1 PE=2 SV=1
Length = 176
Score = 121 bits (302), Expect = 8e-027
Identities = 58/124 (46%), Positives = 91/124 (73%), Gaps = 2/124 (1%)
Frame = +2
Query: 134 EDASLPKATMTKIIKEMLPADVRVARDAQDLLIECCVEFINLISSESNEVCNKEDKRTIA 313
+D ++P+A + K+IKE LP +VRVA DA++L++ CC EFI+LISSE+NE+CNK +K+TI+
Sbjct: 9 DDLTIPRAAINKMIKETLP-NVRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTIS 67
Query: 314 PEHVLKALQVLGFGEYVEEVYAAYEQHKYETMQDSQRSVKMNSGAEMTEEEAAAEQQRMF 493
PEHV++AL+ LGFG Y+ EV ++ K ++ + S ++ + + EEE +QQ +F
Sbjct: 68 PEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLEN-LGIPEEELLRQQQELF 126
Query: 494 AEAR 505
A+AR
Sbjct: 127 AKAR 130
>sp|Q01658|NC2B_HUMAN Protein Dr1 OS=Homo sapiens GN=DR1 PE=1 SV=1
Length = 176
Score = 121 bits (302), Expect = 8e-027
Identities = 58/124 (46%), Positives = 91/124 (73%), Gaps = 2/124 (1%)
Frame = +2
Query: 134 EDASLPKATMTKIIKEMLPADVRVARDAQDLLIECCVEFINLISSESNEVCNKEDKRTIA 313
+D ++P+A + K+IKE LP +VRVA DA++L++ CC EFI+LISSE+NE+CNK +K+TI+
Sbjct: 9 DDLTIPRAAINKMIKETLP-NVRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTIS 67
Query: 314 PEHVLKALQVLGFGEYVEEVYAAYEQHKYETMQDSQRSVKMNSGAEMTEEEAAAEQQRMF 493
PEHV++AL+ LGFG Y+ EV ++ K ++ + S ++ + + EEE +QQ +F
Sbjct: 68 PEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLEN-LGIPEEELLRQQQELF 126
Query: 494 AEAR 505
A+AR
Sbjct: 127 AKAR 130
>sp|Q91WV0|NC2B_MOUSE Protein Dr1 OS=Mus musculus GN=Dr1 PE=2 SV=1
Length = 176
Score = 121 bits (302), Expect = 8e-027
Identities = 58/124 (46%), Positives = 91/124 (73%), Gaps = 2/124 (1%)
Frame = +2
Query: 134 EDASLPKATMTKIIKEMLPADVRVARDAQDLLIECCVEFINLISSESNEVCNKEDKRTIA 313
+D ++P+A + K+IKE LP +VRVA DA++L++ CC EFI+LISSE+NE+CNK +K+TI+
Sbjct: 9 DDLTIPRAAINKMIKETLP-NVRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTIS 67
Query: 314 PEHVLKALQVLGFGEYVEEVYAAYEQHKYETMQDSQRSVKMNSGAEMTEEEAAAEQQRMF 493
PEHV++AL+ LGFG Y+ EV ++ K ++ + S ++ + + EEE +QQ +F
Sbjct: 68 PEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLEN-LGIPEEELLRQQQELF 126
Query: 494 AEAR 505
A+AR
Sbjct: 127 AKAR 130
>sp|Q5XI68|NC2B_RAT Protein Dr1 OS=Rattus norvegicus GN=Dr1 PE=2 SV=1
Length = 176
Score = 121 bits (302), Expect = 8e-027
Identities = 58/124 (46%), Positives = 91/124 (73%), Gaps = 2/124 (1%)
Frame = +2
Query: 134 EDASLPKATMTKIIKEMLPADVRVARDAQDLLIECCVEFINLISSESNEVCNKEDKRTIA 313
+D ++P+A + K+IKE LP +VRVA DA++L++ CC EFI+LISSE+NE+CNK +K+TI+
Sbjct: 9 DDLTIPRAAINKMIKETLP-NVRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTIS 67
Query: 314 PEHVLKALQVLGFGEYVEEVYAAYEQHKYETMQDSQRSVKMNSGAEMTEEEAAAEQQRMF 493
PEHV++AL+ LGFG Y+ EV ++ K ++ + S ++ + + EEE +QQ +F
Sbjct: 68 PEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLEN-LGIPEEELLRQQQELF 126
Query: 494 AEAR 505
A+AR
Sbjct: 127 AKAR 130
>sp|O14348|NC2B_SCHPO Negative cofactor 2 complex subunit beta
OS=Schizosaccharomyces pombe GN=ncb2 PE=2 SV=1
Length = 161
Score = 118 bits (294), Expect = 6e-026
Identities = 55/130 (42%), Positives = 87/130 (66%), Gaps = 1/130 (0%)
Frame = +2
Query: 122 GKSKEDASLPKATMTKIIKEMLPADVRVARDAQDLLIECCVEFINLISSESNEVCNKEDK 301
G + ++ SLPKAT+ K++ ++LP D+ ++A+DLLIECCVEFI+L+SSE+NE+C KE K
Sbjct: 4 GFADDELSLPKATVQKMVSDILPVDLTFTKEARDLLIECCVEFIHLVSSEANEICEKEAK 63
Query: 302 RTIAPEHVLKALQVLGFGEYVEEVYAAYEQHKYETMQDSQRSVKMNSGAEMTEEEAAAEQ 481
+TIA EH++KAL+ L F EY+ E +HK + ++S K ++ +E +Q
Sbjct: 64 KTIAAEHIIKALENLEFKEYIAEALEVAAEHKEQQKNREKKSSKFEQSG-VSRDELLRQQ 122
Query: 482 QRMFAEARAR 511
+ + + AR R
Sbjct: 123 EELLSRARER 132
>sp|Q9VJQ5|NC2B_DROME Protein Dr1 OS=Drosophila melanogaster GN=NC2beta PE=1
SV=1
Length = 183
Score = 107 bits (267), Expect = 9e-023
Identities = 55/124 (44%), Positives = 87/124 (70%), Gaps = 2/124 (1%)
Frame = +2
Query: 134 EDASLPKATMTKIIKEMLPADVRVARDAQDLLIECCVEFINLISSESNEVCNKEDKRTIA 313
++ +LP+A++ KIIKE++P VRVA ++++L++ CC EFI+LISSE+NEVCN +K+TI
Sbjct: 16 DELTLPRASINKIIKELVPT-VRVANESRELILNCCSEFIHLISSEANEVCNMRNKKTIN 74
Query: 314 PEHVLKALQVLGFGEYVEEVYAAYEQHKYETMQDSQRSVKMNSGAEMTEEEAAAEQQRMF 493
EHVL+AL+ LGF +Y +E A K + ++S ++ + + EEE +QQ +F
Sbjct: 75 AEHVLEALERLGFHDYKQEAEAVLHDCKEVAAKRRRQSTRLEN-LGIPEEELLRQQQELF 133
Query: 494 AEAR 505
A+AR
Sbjct: 134 AKAR 137
>sp|Q92317|NCB2_YEAST Negative cofactor 2 complex subunit beta OS=Saccharomyces
cerevisiae GN=NCB2 PE=1 SV=1
Length = 146
Score = 89 bits (219), Expect = 3e-017
Identities = 49/143 (34%), Positives = 94/143 (65%), Gaps = 8/143 (5%)
Frame = +2
Query: 134 EDASLPKATMTKIIKEMLPADVRVARDAQDLLIECCVEFINLISSESNEVCNKEDKRTIA 313
++ SLPKAT+ K+I E+L D+ +DA++++I +EFI ++SS ++E+ + E K+TIA
Sbjct: 6 DNVSLPKATVQKMISEILDQDLMFTKDAREIIINSGIEFIMILSSMASEMADNEAKKTIA 65
Query: 314 PEHVLKALQVLGFGEYV---EEVYAAYEQHKYETMQDSQRSVKMNSGAEMTEEEAAAEQQ 484
PEHV+KAL+ L + E++ EE+ ++ + +++++ S SG ++EEE +Q+
Sbjct: 66 PEHVIKALEELEYNEFIPFLEEILLNFKGS--QKVKETRDSKFKKSG--LSEEELLRQQE 121
Query: 485 RMFAEARARM-NGGVSVPQPDQE 550
+F ++R+R+ + VS P ++
Sbjct: 122 ELFRQSRSRLHHNSVSDPVKSED 144
>sp|Q642A5|DPOE3_RAT DNA polymerase epsilon subunit 3 OS=Rattus norvegicus
GN=Pole3 PE=2 SV=1
Length = 145
Score = 55 bits (132), Expect = 4e-007
Identities = 31/120 (25%), Positives = 62/120 (51%), Gaps = 3/120 (2%)
Frame = +2
Query: 134 EDASLPKATMTKIIKEMLPADVRVARDAQDLLIECCVEFINLISSESNEVCNKEDKRTIA 313
ED +LP A +T+IIKE LP V ++++A+ + F+ +S +N K ++T+
Sbjct: 6 EDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLN 65
Query: 314 PEHVLKALQVLGFGEYV---EEVYAAYEQHKYETMQDSQRSVKMNSGAEMTEEEAAAEQQ 484
VL A++ + F +V +E AY + + + S++ K + E++ + E++
Sbjct: 66 ASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQKKKDKDKKDCEEQDKSREEE 125
>sp|Q9JKP7|DPOE3_MOUSE DNA polymerase epsilon subunit 3 OS=Mus musculus GN=Pole3
PE=2 SV=1
Length = 145
Score = 54 bits (128), Expect = 1e-006
Identities = 29/128 (22%), Positives = 62/128 (48%)
Frame = +2
Query: 134 EDASLPKATMTKIIKEMLPADVRVARDAQDLLIECCVEFINLISSESNEVCNKEDKRTIA 313
ED +LP A +T+IIKE LP V ++++A+ + F+ +S +N K ++T+
Sbjct: 6 EDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLN 65
Query: 314 PEHVLKALQVLGFGEYVEEVYAAYEQHKYETMQDSQRSVKMNSGAEMTEEEAAAEQQRMF 493
VL A++ + F ++ + A E ++ + + S + + + E + + +
Sbjct: 66 ASDVLSAMEEMEFQRFITPLKEALEAYRRDEKGKKEASEQKKKDKDKKDSEEQDKSREVE 125
Query: 494 AEARARMN 517
E R++
Sbjct: 126 EEDEERLD 133
>sp|Q3SZN5|DPOE3_BOVIN DNA polymerase epsilon subunit 3 OS=Bos taurus GN=POLE3
PE=2 SV=1
Length = 147
Score = 54 bits (127), Expect = 1e-006
Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 2/142 (1%)
Frame = +2
Query: 134 EDASLPKATMTKIIKEMLPADVRVARDAQDLLIECCVEFINLISSESNEVCNKEDKRTIA 313
ED +LP A +T+IIKE LP V ++++A+ + F+ +S +N K ++T+
Sbjct: 6 EDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLN 65
Query: 314 PEHVLKALQVLGFGEYVEEVYAAYEQHKYETMQDSQRSVKMNSGAEMTEEEAAAEQQRMF 493
VL A++ + F +V + A E ++ E Q ++ + ++ + EQ +
Sbjct: 66 ASDVLSAMEEMEFQRFVTPLKEALEAYRRE--QKGKKEASEQKKKDKDKKTDSEEQDKSR 123
Query: 494 AEARARMNGGVSVPQPDQEQQV 559
E + + ++E++V
Sbjct: 124 DEDNDEDEERLEEEEQNEEEEV 145
>sp|Q9NRF9|DPOE3_HUMAN DNA polymerase epsilon subunit 3 OS=Homo sapiens GN=POLE3
PE=1 SV=1
Length = 147
Score = 54 bits (127), Expect = 1e-006
Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 2/142 (1%)
Frame = +2
Query: 134 EDASLPKATMTKIIKEMLPADVRVARDAQDLLIECCVEFINLISSESNEVCNKEDKRTIA 313
ED +LP A +T+IIKE LP V ++++A+ + F+ +S +N K ++T+
Sbjct: 6 EDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLN 65
Query: 314 PEHVLKALQVLGFGEYVEEVYAAYEQHKYETMQDSQRSVKMNSGAEMTEEEAAAEQQRMF 493
VL A++ + F +V + A E ++ E Q ++ + ++ + EQ +
Sbjct: 66 ASDVLSAMEEMEFQRFVTPLKEALEAYRRE--QKGKKEASEQKKKDKDKKTDSEEQDKSR 123
Query: 494 AEARARMNGGVSVPQPDQEQQV 559
E + + ++E++V
Sbjct: 124 DEDNDEDEERLEEEEQNEEEEV 145
>sp|Q5R4W3|DPOE3_PONAB DNA polymerase epsilon subunit 3 OS=Pongo abelii GN=POLE3
PE=2 SV=1
Length = 147
Score = 54 bits (127), Expect = 1e-006
Identities = 33/142 (23%), Positives = 68/142 (47%), Gaps = 2/142 (1%)
Frame = +2
Query: 134 EDASLPKATMTKIIKEMLPADVRVARDAQDLLIECCVEFINLISSESNEVCNKEDKRTIA 313
ED +LP A +T+IIKE LP V ++++A+ + F+ +S +N K ++T+
Sbjct: 6 EDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLN 65
Query: 314 PEHVLKALQVLGFGEYVEEVYAAYEQHKYETMQDSQRSVKMNSGAEMTEEEAAAEQQRMF 493
VL A++ + F +V + A E ++ E Q ++ + ++ + EQ +
Sbjct: 66 ASDVLSAMEEMEFQRFVTPLKEALEAYRRE--QKGKKEASEQKKKDKDKKTDSEEQDKSR 123
Query: 494 AEARARMNGGVSVPQPDQEQQV 559
E + + ++E++V
Sbjct: 124 DEDNDEDEERLEEEEQNEEEEV 145
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106,807,929,624
Number of Sequences: 518415
Number of Extensions: 106807929624
Number of Successful Extensions: 680323231
Number of sequences better than 0.0: 0
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