BLASTX 7.6.2
Query= UN25982 /QuerySize=853
(852 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9BY50|SC11C_HUMAN Signal peptidase complex catalytic subunit... 206 2e-052
sp|Q5RC30|SC11C_PONAB Signal peptidase complex catalytic subunit... 206 2e-052
sp|Q9WTR7|SC11C_RAT Signal peptidase complex catalytic subunit S... 205 4e-052
sp|P13679|SC11C_CANFA Signal peptidase complex catalytic subunit... 205 6e-052
sp|Q9D8V7|SC11C_MOUSE Signal peptidase complex catalytic subunit... 205 6e-052
sp|P67810|SC11A_BOVIN Signal peptidase complex catalytic subunit... 203 2e-051
sp|P67811|SC11A_CANFA Signal peptidase complex catalytic subunit... 203 2e-051
sp|P67812|SC11A_HUMAN Signal peptidase complex catalytic subunit... 203 2e-051
sp|Q5R9C7|SC11A_PONAB Signal peptidase complex catalytic subunit... 203 2e-051
sp|Q9R0P6|SC11A_MOUSE Signal peptidase complex catalytic subunit... 202 3e-051
sp|P42667|SC11A_RAT Signal peptidase complex catalytic subunit S... 200 1e-050
sp|Q86JD4|SEC11_DICDI Signal peptidase complex catalytic subunit... 195 3e-049
sp|P0C7V7|SC11B_HUMAN Putative signal peptidase complex catalyti... 170 2e-041
sp|O74323|SEC11_SCHPO Signal peptidase complex catalytic subunit... 61 1e-008
>sp|Q9BY50|SC11C_HUMAN Signal peptidase complex catalytic subunit SEC11C OS=Homo
sapiens GN=SEC11C PE=1 SV=3
Length = 192
Score = 206 bits (522), Expect = 2e-052
Identities = 103/171 (60%), Positives = 128/171 (74%), Gaps = 2/171 (1%)
Frame = +3
Query: 138 IKSIKIRQLLTQAVTLGMIVTSALIIWKGLMCVTGTESPVVVVLSGSMEPGFQRGDILFL 317
+K + RQL Q + MIV+SAL+IWKGL+ +TG+ESP+VVVLSGSMEP F RGD+LFL
Sbjct: 22 LKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFL 81
Query: 318 TMTKE-PIRTGEIVVFKIDGRDIPIVHRAIEVHERKSTGAVDVLTKGDNNEVDDIGLYAD 494
T +E PIR GEIVVFK++GRDIPIVHR I+VHE K G + LTKGDNNEVDD GLY +
Sbjct: 82 TNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHE-KDNGDIKFLTKGDNNEVDDRGLYKE 140
Query: 495 GQMWLHRHHIMGRAVAFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 647
GQ WL + ++GRA FLPYVG VTIIM + P KY L+ +G V+ ++
Sbjct: 141 GQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRE 191
>sp|Q5RC30|SC11C_PONAB Signal peptidase complex catalytic subunit SEC11C
OS=Pongo abelii GN=SEC11C PE=2 SV=3
Length = 192
Score = 206 bits (522), Expect = 2e-052
Identities = 103/171 (60%), Positives = 128/171 (74%), Gaps = 2/171 (1%)
Frame = +3
Query: 138 IKSIKIRQLLTQAVTLGMIVTSALIIWKGLMCVTGTESPVVVVLSGSMEPGFQRGDILFL 317
+K + RQL Q + MIV+SAL+IWKGL+ +TG+ESP+VVVLSGSMEP F RGD+LFL
Sbjct: 22 LKKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFL 81
Query: 318 TMTKE-PIRTGEIVVFKIDGRDIPIVHRAIEVHERKSTGAVDVLTKGDNNEVDDIGLYAD 494
T +E PIR GEIVVFK++GRDIPIVHR I+VHE K G + LTKGDNNEVDD GLY +
Sbjct: 82 TNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHE-KDNGDIKFLTKGDNNEVDDRGLYKE 140
Query: 495 GQMWLHRHHIMGRAVAFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 647
GQ WL + ++GRA FLPYVG VTIIM + P KY L+ +G V+ ++
Sbjct: 141 GQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRE 191
>sp|Q9WTR7|SC11C_RAT Signal peptidase complex catalytic subunit SEC11C OS=Rattus
norvegicus GN=Sec11c PE=2 SV=3
Length = 192
Score = 205 bits (520), Expect = 4e-052
Identities = 102/171 (59%), Positives = 128/171 (74%), Gaps = 2/171 (1%)
Frame = +3
Query: 138 IKSIKIRQLLTQAVTLGMIVTSALIIWKGLMCVTGTESPVVVVLSGSMEPGFQRGDILFL 317
++ + RQL Q + MIV+SAL+IWKGL+ +TG+ESP+VVVLSGSMEP F RGD+LFL
Sbjct: 22 LRKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFL 81
Query: 318 TMTKE-PIRTGEIVVFKIDGRDIPIVHRAIEVHERKSTGAVDVLTKGDNNEVDDIGLYAD 494
T +E PIR GEIVVFK++GRDIPIVHR I+VHE K G + LTKGDNNEVDD GLY +
Sbjct: 82 TNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHE-KDNGDIKFLTKGDNNEVDDRGLYKE 140
Query: 495 GQMWLHRHHIMGRAVAFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 647
GQ WL + ++GRA FLPYVG VTIIM + P KY L+ +G V+ ++
Sbjct: 141 GQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALVAVMGAYVLLKRE 191
>sp|P13679|SC11C_CANFA Signal peptidase complex catalytic subunit SEC11C
OS=Canis familiaris GN=SEC11C PE=1 SV=3
Length = 192
Score = 205 bits (519), Expect = 6e-052
Identities = 102/171 (59%), Positives = 128/171 (74%), Gaps = 2/171 (1%)
Frame = +3
Query: 138 IKSIKIRQLLTQAVTLGMIVTSALIIWKGLMCVTGTESPVVVVLSGSMEPGFQRGDILFL 317
++ + RQL Q + MIV+SAL+IWKGL+ +TG+ESP+VVVLSGSMEP F RGD+LFL
Sbjct: 22 LRKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFL 81
Query: 318 TMTKE-PIRTGEIVVFKIDGRDIPIVHRAIEVHERKSTGAVDVLTKGDNNEVDDIGLYAD 494
T +E PIR GEIVVFK++GRDIPIVHR I+VHE K G + LTKGDNNEVDD GLY +
Sbjct: 82 TNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHE-KDNGDIKFLTKGDNNEVDDRGLYKE 140
Query: 495 GQMWLHRHHIMGRAVAFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 647
GQ WL + ++GRA FLPYVG VTIIM + P KY L+ +G V+ ++
Sbjct: 141 GQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRE 191
>sp|Q9D8V7|SC11C_MOUSE Signal peptidase complex catalytic subunit SEC11C OS=Mus
musculus GN=Sec11c PE=2 SV=3
Length = 192
Score = 205 bits (519), Expect = 6e-052
Identities = 102/171 (59%), Positives = 128/171 (74%), Gaps = 2/171 (1%)
Frame = +3
Query: 138 IKSIKIRQLLTQAVTLGMIVTSALIIWKGLMCVTGTESPVVVVLSGSMEPGFQRGDILFL 317
++ + RQL Q + MIV+SAL+IWKGL+ +TG+ESP+VVVLSGSMEP F RGD+LFL
Sbjct: 22 LRKMNKRQLYYQVLNFAMIVSSALMIWKGLIVLTGSESPIVVVLSGSMEPAFHRGDLLFL 81
Query: 318 TMTKE-PIRTGEIVVFKIDGRDIPIVHRAIEVHERKSTGAVDVLTKGDNNEVDDIGLYAD 494
T +E PIR GEIVVFK++GRDIPIVHR I+VHE K G + LTKGDNNEVDD GLY +
Sbjct: 82 TNFREDPIRAGEIVVFKVEGRDIPIVHRVIKVHE-KDNGDIKFLTKGDNNEVDDRGLYKE 140
Query: 495 GQMWLHRHHIMGRAVAFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 647
GQ WL + ++GRA FLPYVG VTIIM + P KY L+ +G V+ ++
Sbjct: 141 GQNWLEKKDVVGRARGFLPYVGMVTIIMNDYPKFKYALLAVMGAYVLLKRE 191
>sp|P67810|SC11A_BOVIN Signal peptidase complex catalytic subunit SEC11A OS=Bos
taurus GN=SEC11A PE=2 SV=1
Length = 179
Score = 203 bits (514), Expect = 2e-051
Identities = 98/174 (56%), Positives = 130/174 (74%), Gaps = 2/174 (1%)
Frame = +3
Query: 129 MDSIKSIKIRQLLTQAVTLGMIVTSALIIWKGLMCVTGTESPVVVVLSGSMEPGFQRGDI 308
+D ++ + RQL Q + GMIV+SAL+IWKGLM +TG+ESP+VVVLSGSMEP F RGD+
Sbjct: 7 LDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDL 66
Query: 309 LFLT-MTKEPIRTGEIVVFKIDGRDIPIVHRAIEVHERKSTGAVDVLTKGDNNEVDDIGL 485
LFLT ++PIR GEIVVF+I+GR+IPIVHR +++HE K G + LTKGDNN VDD GL
Sbjct: 67 LFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHE-KQNGHIKFLTKGDNNAVDDRGL 125
Query: 486 YADGQMWLHRHHIMGRAVAFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 647
Y GQ WL + ++GRA F+PY+G VTI+M + P KY ++ LGL V+ ++
Sbjct: 126 YKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE 179
>sp|P67811|SC11A_CANFA Signal peptidase complex catalytic subunit SEC11A
OS=Canis familiaris GN=SEC11A PE=1 SV=1
Length = 179
Score = 203 bits (514), Expect = 2e-051
Identities = 98/174 (56%), Positives = 130/174 (74%), Gaps = 2/174 (1%)
Frame = +3
Query: 129 MDSIKSIKIRQLLTQAVTLGMIVTSALIIWKGLMCVTGTESPVVVVLSGSMEPGFQRGDI 308
+D ++ + RQL Q + GMIV+SAL+IWKGLM +TG+ESP+VVVLSGSMEP F RGD+
Sbjct: 7 LDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDL 66
Query: 309 LFLT-MTKEPIRTGEIVVFKIDGRDIPIVHRAIEVHERKSTGAVDVLTKGDNNEVDDIGL 485
LFLT ++PIR GEIVVF+I+GR+IPIVHR +++HE K G + LTKGDNN VDD GL
Sbjct: 67 LFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHE-KQNGHIKFLTKGDNNAVDDRGL 125
Query: 486 YADGQMWLHRHHIMGRAVAFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 647
Y GQ WL + ++GRA F+PY+G VTI+M + P KY ++ LGL V+ ++
Sbjct: 126 YKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE 179
>sp|P67812|SC11A_HUMAN Signal peptidase complex catalytic subunit SEC11A OS=Homo
sapiens GN=SEC11A PE=1 SV=1
Length = 179
Score = 203 bits (514), Expect = 2e-051
Identities = 98/174 (56%), Positives = 130/174 (74%), Gaps = 2/174 (1%)
Frame = +3
Query: 129 MDSIKSIKIRQLLTQAVTLGMIVTSALIIWKGLMCVTGTESPVVVVLSGSMEPGFQRGDI 308
+D ++ + RQL Q + GMIV+SAL+IWKGLM +TG+ESP+VVVLSGSMEP F RGD+
Sbjct: 7 LDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDL 66
Query: 309 LFLT-MTKEPIRTGEIVVFKIDGRDIPIVHRAIEVHERKSTGAVDVLTKGDNNEVDDIGL 485
LFLT ++PIR GEIVVF+I+GR+IPIVHR +++HE K G + LTKGDNN VDD GL
Sbjct: 67 LFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHE-KQNGHIKFLTKGDNNAVDDRGL 125
Query: 486 YADGQMWLHRHHIMGRAVAFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 647
Y GQ WL + ++GRA F+PY+G VTI+M + P KY ++ LGL V+ ++
Sbjct: 126 YKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE 179
>sp|Q5R9C7|SC11A_PONAB Signal peptidase complex catalytic subunit SEC11A
OS=Pongo abelii GN=SEC11A PE=2 SV=1
Length = 179
Score = 203 bits (514), Expect = 2e-051
Identities = 98/174 (56%), Positives = 130/174 (74%), Gaps = 2/174 (1%)
Frame = +3
Query: 129 MDSIKSIKIRQLLTQAVTLGMIVTSALIIWKGLMCVTGTESPVVVVLSGSMEPGFQRGDI 308
+D ++ + RQL Q + GMIV+SAL+IWKGLM +TG+ESP+VVVLSGSMEP F RGD+
Sbjct: 7 LDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDL 66
Query: 309 LFLT-MTKEPIRTGEIVVFKIDGRDIPIVHRAIEVHERKSTGAVDVLTKGDNNEVDDIGL 485
LFLT ++PIR GEIVVF+I+GR+IPIVHR +++HE K G + LTKGDNN VDD GL
Sbjct: 67 LFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHE-KQNGHIKFLTKGDNNAVDDRGL 125
Query: 486 YADGQMWLHRHHIMGRAVAFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 647
Y GQ WL + ++GRA F+PY+G VTI+M + P KY ++ LGL V+ ++
Sbjct: 126 YKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE 179
>sp|Q9R0P6|SC11A_MOUSE Signal peptidase complex catalytic subunit SEC11A OS=Mus
musculus GN=Sec11a PE=2 SV=1
Length = 179
Score = 202 bits (513), Expect = 3e-051
Identities = 98/174 (56%), Positives = 130/174 (74%), Gaps = 2/174 (1%)
Frame = +3
Query: 129 MDSIKSIKIRQLLTQAVTLGMIVTSALIIWKGLMCVTGTESPVVVVLSGSMEPGFQRGDI 308
+D ++ + RQL Q + GMIV+SAL+IWKGLM +TG+ESP+VVVLSGSMEP F RGD+
Sbjct: 7 LDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMVITGSESPIVVVLSGSMEPAFHRGDL 66
Query: 309 LFLT-MTKEPIRTGEIVVFKIDGRDIPIVHRAIEVHERKSTGAVDVLTKGDNNEVDDIGL 485
LFLT ++PIR GEIVVF+I+GR+IPIVHR +++HE K G + LTKGDNN VDD GL
Sbjct: 67 LFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHE-KQDGHIKFLTKGDNNAVDDRGL 125
Query: 486 YADGQMWLHRHHIMGRAVAFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 647
Y GQ WL + ++GRA F+PY+G VTI+M + P KY ++ LGL V+ ++
Sbjct: 126 YKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFKYAVLFLLGLFVLVHRE 179
>sp|P42667|SC11A_RAT Signal peptidase complex catalytic subunit SEC11A OS=Rattus
norvegicus GN=Sec11a PE=2 SV=1
Length = 179
Score = 200 bits (508), Expect = 1e-050
Identities = 97/174 (55%), Positives = 129/174 (74%), Gaps = 2/174 (1%)
Frame = +3
Query: 129 MDSIKSIKIRQLLTQAVTLGMIVTSALIIWKGLMCVTGTESPVVVVLSGSMEPGFQRGDI 308
+D ++ + RQL Q + GMIV+SAL+IWKGLM +TG+ESP+VVVLSGSMEP F RGD+
Sbjct: 7 LDDVRRMNKRQLYYQVLNFGMIVSSALMIWKGLMLITGSESPIVVVLSGSMEPAFHRGDL 66
Query: 309 LFLT-MTKEPIRTGEIVVFKIDGRDIPIVHRAIEVHERKSTGAVDVLTKGDNNEVDDIGL 485
LFLT ++PIR GEIVVF+I+GR+IPIVHR +++HE K G + LTKGDNN VDD GL
Sbjct: 67 LFLTNRVEDPIRVGEIVVFRIEGREIPIVHRVLKIHE-KQDGHIKFLTKGDNNAVDDRGL 125
Query: 486 YADGQMWLHRHHIMGRAVAFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 647
Y GQ WL + ++GRA F+PY+G VTI+M + P Y ++ LGL V+ ++
Sbjct: 126 YKQGQHWLEKKDVVGRARGFVPYIGIVTILMNDYPKFSYAVLFLLGLFVLVHRE 179
>sp|Q86JD4|SEC11_DICDI Signal peptidase complex catalytic subunit sec11
OS=Dictyostelium discoideum GN=sec11 PE=3 SV=1
Length = 179
Score = 195 bits (495), Expect = 3e-049
Identities = 94/173 (54%), Positives = 126/173 (72%), Gaps = 1/173 (0%)
Frame = +3
Query: 129 MDSIKSIKIRQLLTQAVTLGMIVTSALIIWKGLMCVTGTESPVVVVLSGSMEPGFQRGDI 308
++ SI Q+ Q V G+IV +AL+IWKGLM +G+ESP+VVVLSGSM P F RGD+
Sbjct: 8 INPFSSIPKHQIAQQIVNFGLIVATALMIWKGLMIFSGSESPIVVVLSGSMIPAFFRGDL 67
Query: 309 LFLTMTKEPIRTGEIVVFKIDGRDIPIVHRAIEVHERKSTGAVDVLTKGDNNEVDDIGLY 488
L+L M P R GEIVVFKI+G++IPIVHR +++HE K G D+ TKGDNN VDD+GLY
Sbjct: 68 LYLNMEDGPFRVGEIVVFKIEGKEIPIVHRILQIHE-KEDGLYDIRTKGDNNNVDDVGLY 126
Query: 489 ADGQMWLHRHHIMGRAVAFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 647
+ GQ WL R HI+GRA FLP VG VTI+M + P +K+ L+ L + V+++++
Sbjct: 127 SPGQRWLSRDHIIGRAKGFLPSVGMVTIVMHDYPQLKFFLVFVLAVFVLSTRE 179
>sp|P0C7V7|SC11B_HUMAN Putative signal peptidase complex catalytic subunit
SEC11B OS=Homo sapiens GN=SEC11B PE=5 SV=1
Length = 166
Score = 170 bits (429), Expect = 2e-041
Identities = 87/164 (53%), Positives = 116/164 (70%), Gaps = 3/164 (1%)
Frame = +3
Query: 159 QLLTQAVTLGMIVTSALIIWKGLMCVTGTESPVVVVLSGSMEPGFQRGDILFLT-MTKEP 335
+L Q + GMIV+SAL+IWKGLM +TG+ESP +V+LSGSMEP F RG +LFLT ++P
Sbjct: 5 RLYYQVLNFGMIVSSALMIWKGLMVITGSESP-IVLLSGSMEPAFHRGYLLFLTNRVEDP 63
Query: 336 IRTGEIVVFKIDGRDIPIVHRAIEVHERKSTGAVDVLTKGDNNEVDDIGLYADGQMWLHR 515
IR GEI V +I+GR IPIVHR +++HE K G + LTKGDNN VDD GLY Q WL +
Sbjct: 64 IRVGEIAVLRIEGRKIPIVHRVLKIHE-KQNGHIKFLTKGDNNAVDDRGLYKQDQHWLEK 122
Query: 516 HHIMGRAVAFLPYVGWVTIIMTEKPIIKYILIGALGLLVITSKD 647
++GRA F+PY+G T +M + P KY ++ LGL V+ ++
Sbjct: 123 KDVVGRARGFVPYIGIGTSLMNDYPKHKYEVLFLLGLFVLVHRE 166
>sp|O74323|SEC11_SCHPO Signal peptidase complex catalytic subunit sec11
OS=Schizosaccharomyces pombe GN=sec11 PE=2 SV=1
Length = 189
Score = 61 bits (146), Expect = 1e-008
Identities = 32/60 (53%), Positives = 43/60 (71%)
Frame = +3
Query: 138 IKSIKIRQLLTQAVTLGMIVTSALIIWKGLMCVTGTESPVVVVLSGSMEPGFQRGDILFL 317
++ + RQ L Q + L ++++SA + +K L VT ESPVVVVLS SMEP FQRGD+LFL
Sbjct: 1 MQKLSFRQGLAQILNLLLVLSSAYMGYKTLSFVTDCESPVVVVLSESMEPSFQRGDLLFL 60
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106,807,929,624
Number of Sequences: 518415
Number of Extensions: 106807929624
Number of Successful Extensions: 680323231
Number of sequences better than 0.0: 0
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