BLASTX 7.6.2
Query= UN27724 /QuerySize=1675
(1674 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P34756|FAB1_YEAST 1-phosphatidylinositol-3-phosphate 5-kinase... 272 9e-072
sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase... 265 7e-070
sp|Q9Z1T6|FYV1_MOUSE 1-phosphatidylinositol-3-phosphate 5-kinase... 263 3e-069
sp|O59722|FAB1_SCHPO 1-phosphatidylinositol-3-phosphate 5-kinase... 261 2e-068
sp|B0G126|FYV1_DICDI 1-phosphatidylinositol-3-phosphate 5-kinase... 254 2e-066
sp|O96838|FYV1_DROME Putative 1-phosphatidylinositol-3-phosphate... 216 6e-055
sp|Q5PQ01|PI42C_XENLA Phosphatidylinositol-5-phosphate 4-kinase ... 62 9e-009
sp|Q91XU3|PI42C_MOUSE Phosphatidylinositol-5-phosphate 4-kinase ... 62 1e-008
sp|O88370|PI42C_RAT Phosphatidylinositol-5-phosphate 4-kinase ty... 62 1e-008
sp|Q8TBX8|PI42C_HUMAN Phosphatidylinositol-5-phosphate 4-kinase ... 61 2e-008
sp|Q0P5F7|PI42C_BOVIN Phosphatidylinositol-5-phosphate 4-kinase ... 60 3e-008
sp|Q55GN6|Y7588_DICDI Probable phosphatidylinositol phosphate ki... 55 1e-006
sp|P78356|PI42B_HUMAN Phosphatidylinositol-5-phosphate 4-kinase ... 53 5e-006
sp|Q80XI4|PI42B_MOUSE Phosphatidylinositol-5-phosphate 4-kinase ... 53 5e-006
sp|O88377|PI42B_RAT Phosphatidylinositol-5-phosphate 4-kinase ty... 52 9e-006
>sp|P34756|FAB1_YEAST 1-phosphatidylinositol-3-phosphate 5-kinase FAB1
OS=Saccharomyces cerevisiae GN=FAB1 PE=1 SV=1
Length = 2278
Score = 272 bits (693), Expect = 9e-072
Identities = 134/276 (48%), Positives = 184/276 (66%), Gaps = 3/276 (1%)
Frame = +2
Query: 620 EGKVKFSVTSYFATQFDTLRKTCCPSEVDFVRSLSRCQRWSAQGGKSNVYFAKSLDERFI 799
EG S +F FD RK C E +F++SLSRC +W + GGKS F K+LD+RFI
Sbjct: 1999 EGLTVMSCKIFFTEHFDVFRKICDCQE-NFIQSLSRCVKWDSNGGKSGSGFLKTLDDRFI 2057
Query: 800 IKQVVKTELDSFEDFAPEYFKYMKESLSSGSPTCLAKILGIYQVSIKHS-KGGKETKMDL 976
IK++ EL++F FAP YF+YM +++ PT LAK+ G YQ+ +K S K KMD+
Sbjct: 2058 IKELSHAELEAFIKFAPSYFEYMAQAMFHDLPTTLAKVFGFYQIQVKSSISSSKSYKMDV 2117
Query: 977 MVMENLFYNRKIFRIYDLKGSARSRYNPNTSGKDKVLLDMNLLETLRTEPIFLGSKAKRS 1156
++MENLFY +K RI+DLKGS R+R+ T ++VLLD N++E + PI + K+
Sbjct: 2118 IIMENLFYEKKTTRIFDLKGSMRNRHVEQTGKANEVLLDENMVEYIYESPIHVREYDKKL 2177
Query: 1157 LERAIWNDTNFLASVDVMDYSLLVGFDEERKELVLGIIDFMRQYTWDKHLETWVKASGIL 1336
L ++WNDT FLA ++VMDYSL++G D E L +GIIDF+R +TWDK LE+WVK G++
Sbjct: 2178 LRASVWNDTLFLAKMNVMDYSLVIGIDNEGYTLTVGIIDFIRTFTWDKKLESWVKEKGLV 2237
Query: 1337 GGPK-NASPTIVSPKQYKKRFRKAMTTYFLTVPEQW 1441
GG PT+V+P+QYKKRFR+AM Y L VP+ W
Sbjct: 2238 GGASVIKQPTVVTPRQYKKRFREAMERYILMVPDPW 2273
>sp|Q9Y2I7|FYV1_HUMAN 1-phosphatidylinositol-3-phosphate 5-kinase OS=Homo
sapiens GN=PIKFYVE PE=1 SV=3
Length = 2098
Score = 265 bits (677), Expect = 7e-070
Identities = 139/297 (46%), Positives = 198/297 (66%), Gaps = 14/297 (4%)
Frame = +2
Query: 566 SPHLTISFSDRSSSSGATEGKVKFSVTSYFATQFDTLRKTCC-PSEVDFVRSLSRCQRWS 742
+PH+ + FSD ++ KF Y+A +F +R+ SE DF+RSLS W
Sbjct: 1806 NPHVELQFSDANA---------KFYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQ 1856
Query: 743 AQGGKSNVYFAKSLDERFIIKQVVKTELDSFEDFAPEYFKYMKESLSSGSPTCLAKILGI 922
A+GGKS F + D+RFI+KQ+ + E+ SF DFAP YF Y+ ++ PT LAKILG+
Sbjct: 1857 ARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGV 1916
Query: 923 YQVSIKHSKGGKETKMDLMVMENLFYNRKIFRIYDLKGSARSRYNPNTSGK---DKVLLD 1093
Y++ K+S+ E K+DL+VMENLFY RK+ +++DLKGS R+R +GK D VLLD
Sbjct: 1917 YRIGYKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLD 1976
Query: 1094 MNLLETLRTEPIFLGSKAKRSLERAIWNDTNFLASVDVMDYSLLVGFDEERKELVLGIID 1273
NLL+ +R P+++ S +K L +I +D++FL+S ++DYSLLVG D+ ELV+GIID
Sbjct: 1977 ENLLKMVRDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLLVGRDDTSNELVVGIID 2036
Query: 1274 FMRQYTWDKHLETWVKASGILGGPKNASPTIVSPKQYKKRFRKAMTTYFLTVPEQWT 1444
++R +TWDK LE VK++GILGG + PT+VSP+ Y+ RF +AM YFL VP+ WT
Sbjct: 2037 YIRTFTWDKKLEMVVKSTGILGG-QGKMPTVVSPELYRTRFCEAMDKYFLMVPDHWT 2092
>sp|Q9Z1T6|FYV1_MOUSE 1-phosphatidylinositol-3-phosphate 5-kinase OS=Mus
musculus GN=Pikfyve PE=1 SV=2
Length = 2097
Score = 263 bits (672), Expect = 3e-069
Identities = 138/297 (46%), Positives = 197/297 (66%), Gaps = 14/297 (4%)
Frame = +2
Query: 566 SPHLTISFSDRSSSSGATEGKVKFSVTSYFATQFDTLRKTCC-PSEVDFVRSLSRCQRWS 742
+PH+ + FSD ++ KF Y+A +F +R+ SE +F+RSLS W
Sbjct: 1805 NPHVELQFSDANA---------KFYCRLYYAGEFHKMREVILGSSEEEFIRSLSHSSPWQ 1855
Query: 743 AQGGKSNVYFAKSLDERFIIKQVVKTELDSFEDFAPEYFKYMKESLSSGSPTCLAKILGI 922
A+GGKS F + D+RFI+KQ+ + E+ SF DFAP YF Y+ ++ PT LAKILG+
Sbjct: 1856 ARGGKSGAAFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGV 1915
Query: 923 YQVSIKHSKGGKETKMDLMVMENLFYNRKIFRIYDLKGSARSRYNPNTSGK---DKVLLD 1093
Y++ K+S+ E K+DL+VMENLFY RK+ +++DLKGS R+R +GK D VLLD
Sbjct: 1916 YRIGYKNSQNNTEKKLDLLVMENLFYGRKMAQVFDLKGSLRNRNVKTDTGKESCDVVLLD 1975
Query: 1094 MNLLETLRTEPIFLGSKAKRSLERAIWNDTNFLASVDVMDYSLLVGFDEERKELVLGIID 1273
NLL+ +R P+++ S +K L +I +D +FL+S ++DYSLLVG D+ ELV+GIID
Sbjct: 1976 ENLLKMVRDNPLYIRSHSKSVLRTSIHSDAHFLSSHLIIDYSLLVGRDDTSNELVVGIID 2035
Query: 1274 FMRQYTWDKHLETWVKASGILGGPKNASPTIVSPKQYKKRFRKAMTTYFLTVPEQWT 1444
++R +TWDK LE VK++GILGG + PT+VSP+ Y+ RF +AM YFL VP+ WT
Sbjct: 2036 YIRTFTWDKKLEMVVKSTGILGG-QGKMPTVVSPELYRTRFCEAMDKYFLMVPDHWT 2091
>sp|O59722|FAB1_SCHPO 1-phosphatidylinositol-3-phosphate 5-kinase fab1
OS=Schizosaccharomyces pombe GN=fab1 PE=2 SV=2
Length = 1932
Score = 261 bits (665), Expect = 2e-068
Identities = 145/333 (43%), Positives = 196/333 (58%), Gaps = 16/333 (4%)
Frame = +2
Query: 458 RESEPSSTFSTWRSL-----------GSMDTDYIHHAVYGSSQDDKKSPHLTISFSDRSS 604
RE EPSS S S SMD + + GS+Q K +L + +
Sbjct: 1590 REDEPSSLISFTLSSPDYLSKMVEIEDSMDEALTNQGLQGSTQ--FKIENLMLKPTGTHL 1647
Query: 605 SSGATEGKVKFSVTSYFATQFDTLRKTCCPSEVDFVRSLSRCQRWSAQGGKSNVYFAKSL 784
EG + S +FA QF LR+ C E FV SL+RC W + GGKS F K+
Sbjct: 1648 KYQFEEGSARLSCKVFFAEQFSALRR-ACGCEETFVTSLARCSLWESSGGKSGSAFLKTF 1706
Query: 785 DERFIIKQVVKTELDSFEDFAPEYFKYMKESLSSGSPTCLAKILGIYQVSIKHSKGGKET 964
D+++I+K + + E DS +FAP YF Y+ + PT L KI G Y+V I++ G
Sbjct: 1707 DKKYILKVLSRLESDSLLNFAPAYFDYISKVFFHELPTALTKIFGFYRVDIRNPTTGTIC 1766
Query: 965 KMDLMVMENLFYNRKIFRIYDLKGSARSRYNPNTSGKDKVLLDMNLLETLRTEPIFLGSK 1144
K D+M+MEN+FY+ RI+DLKGS R+R+ +T D+VLLD NL+E + PIF+ +
Sbjct: 1767 KTDIMIMENVFYDECPSRIFDLKGSMRNRHVESTGKVDEVLLDENLVELIYESPIFVSEQ 1826
Query: 1145 AKRSLERAIWNDTNFLASVDVMDYSLLVGFDEERKELVLGIIDFMRQYTWDKHLETWVKA 1324
K L +WNDT FL+ +++MDYSL+VG D +KEL +GIIDF+R YTWDK LE+WVK
Sbjct: 1827 LKSLLHSCLWNDTLFLSKLNIMDYSLIVGIDYTKKELYVGIIDFIRTYTWDKKLESWVKE 1886
Query: 1325 SGILGGPKNASPTIVSPKQYKKRFRKAMTTYFL 1423
G++G + PTIV+PKQYK RFRKAM Y L
Sbjct: 1887 KGLVG--RGPEPTIVTPKQYKNRFRKAMDCYIL 1917
>sp|B0G126|FYV1_DICDI 1-phosphatidylinositol-3-phosphate 5-kinase
OS=Dictyostelium discoideum GN=pip5k3 PE=3 SV=1
Length = 2656
Score = 254 bits (648), Expect = 2e-066
Identities = 145/340 (42%), Positives = 210/340 (61%), Gaps = 15/340 (4%)
Frame = +2
Query: 452 SNRESEPSSTFSTWRSLGSMDTDYIHHAVYGSSQDDKKSPHLTISFSDRSSSSGATEGKV 631
+N + ++ + + + + DT+ ++ S+ + ++ +S S+ +
Sbjct: 2271 NNNNNNNNTNNNNEQQINNSDTEGDSDSIKSSNSNIYSEKNIKLSKLMVSTQRKEIRSRF 2330
Query: 632 KFS---------VTSYFATQFDTLRKTCCPSEVDFVRSLSRCQRWSAQGGKSNVYFAKSL 784
KF +SY+ QF LR+ C + +F++SL+R + W+A+GGKS + K+L
Sbjct: 2331 KFEKNGYELNIFCSSYYPVQFHALREYMC-GDQEFIQSLTRSKIWNAKGGKSGSSWNKTL 2389
Query: 785 DERFIIKQVVKTELDSFEDFAPEYFKYMKESLSSGSPTCLAKILGIYQVSIKHSKGGKET 964
D+RFI+KQV + EL+SF DFAP YF+Y+ +S + PT L KILG++ V K S GK
Sbjct: 2390 DDRFILKQVSRIELESFLDFAPLYFEYICKSFLNQIPTALCKILGVFTVRWKDS-NGKAL 2448
Query: 965 KMDLMVMENLFYNRKIFRIYDLKGSARSRYNPNTSGKDKVLLDMNLLETLRTEPIFLGSK 1144
K DL+VMENLF+++ I + YDLKGS R R N S +VLLD NLL+ PI LG
Sbjct: 2449 KKDLIVMENLFHSKCISKTYDLKGSLRGRLVKNES---EVLLDENLLQASFASPICLGEY 2505
Query: 1145 AKRSLERAIWNDTNFLASVDVMDYSLLVGFDEERKELVLGIIDFMRQYTWDKHLETWVKA 1324
K + A+WNDT FL+S++VMDYSLL G D + +LV+GIID+MR++TWDK LE VK
Sbjct: 2506 DKTRVALAVWNDTAFLSSLNVMDYSLLSGIDNQSNQLVVGIIDYMRKFTWDKALEMKVKQ 2565
Query: 1325 SGILGGPKNASPTIVSPKQYKKRFRKAMTTYFLTVPEQWT 1444
SGI+GG PT++SPKQYK RFR AM YF P+++T
Sbjct: 2566 SGIMGGGGKV-PTVISPKQYKLRFRDAMWLYFTLSPDKFT 2604
>sp|O96838|FYV1_DROME Putative 1-phosphatidylinositol-3-phosphate 5-kinase
OS=Drosophila melanogaster GN=fab1 PE=1 SV=2
Length = 1809
Score = 216 bits (548), Expect = 6e-055
Identities = 116/256 (45%), Positives = 168/256 (65%), Gaps = 4/256 (1%)
Frame = +2
Query: 695 SEVDFVRSLSRCQRWSAQGGKSNVYFAKSLDERFIIKQVVKTELDSFEDFAPEYFKYMKE 874
+ + RSL + +W A+GGKS F K+LD+RF++K++ ++ FE FAP+YF+Y+
Sbjct: 1557 ARIALARSLCKSVQWEARGGKSGSRFCKTLDDRFVLKEMNSRDMTIFEPFAPKYFEYIDR 1616
Query: 875 SLSSGSPTCLAKILGIYQVSIKHSKGGKETKMDLMVMENLFYNRKIFRIYDLKGSARSR- 1051
PT LAKI G+++VS+K K + +MVMENLFY I +DLKGS R+R
Sbjct: 1617 CQQQQQPTLLAKIFGVFRVSVK--KKDSFVERSVMVMENLFYGCNIENKFDLKGSERNRL 1674
Query: 1052 YNPNTSGKDKVLLDMNLLETLRTEPIFLGSKAKRSLERAIWNDTNFLASVDVMDYSLLVG 1231
+P+ + VLLD NL++ ++P+++ S +K L AI D++FL VMDYSLLVG
Sbjct: 1675 VDPSNQQGEIVLLDENLVQMSWSKPLYVLSHSKTVLRDAIQRDSSFLEKNLVMDYSLLVG 1734
Query: 1232 FDEERKELVLGIIDFMRQYTWDKHLETWVKASGILGGPKNASPTIVSPKQYKKRFRKAMT 1411
D++ LVLGIID++R +T DK +E+ +K SGILGG K PT+V+P++YK+RF AM
Sbjct: 1735 LDKKNGVLVLGIIDYIRTFTLDKRVESIIKGSGILGG-KGKDPTVVNPERYKQRFIDAMD 1793
Query: 1412 TYFLTVPEQWTS*IKV 1459
YFLTVP++W KV
Sbjct: 1794 RYFLTVPDRWEGLSKV 1809
>sp|Q5PQ01|PI42C_XENLA Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma
OS=Xenopus laevis GN=pip4k2c PE=2 SV=1
Length = 419
Score = 62 bits (150), Expect = 9e-009
Identities = 52/164 (31%), Positives = 85/164 (51%), Gaps = 24/164 (14%)
Frame = +2
Query: 785 DERFII---KQVVKTELDSFEDFAPEYF---KYMKESLSSGSPTCLAKILGIYQVSIKHS 946
D RF++ K +V E+ S ED A + Y + + T L + LG+Y++S+ +
Sbjct: 142 DGRFLLSYDKTLVIKEISS-EDVADMHIILSHYHQHIVKCHESTLLPQFLGMYRLSVDNE 200
Query: 947 KGGKETKMDLMVMENLFYNR-KIFRIYDLKGSARSRYNPNTSGKDKV-----LLDMNLLE 1108
++VM N+F +R + R YDLKGS SR S K+KV L DM+ L
Sbjct: 201 DS------YIIVMRNMFSHRLTVHRKYDLKGSLVSR---EASDKEKVKELPTLKDMDFLN 251
Query: 1109 TLRTEPIFLGSKAKRSLERAIWNDTNFLASVDVMDYSLLVGFDE 1240
+++ +++ + KR+ + D +FL + +MDYSLL+G E
Sbjct: 252 --KSQKVYVDEEQKRNFMEKLKRDVDFLVQLKLMDYSLLLGIHE 293
>sp|Q91XU3|PI42C_MOUSE Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma
OS=Mus musculus GN=Pip4k2c PE=2 SV=1
Length = 421
Score = 62 bits (149), Expect = 1e-008
Identities = 47/163 (28%), Positives = 78/163 (47%), Gaps = 22/163 (13%)
Frame = +2
Query: 785 DERFIIKQ-----VVKTELDSFEDFAPEYFKYMKESLSSGSPTCLAKILGIYQVSIKHSK 949
D RF+I + + + D Y + + T L + LG+Y+VS+++
Sbjct: 138 DGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVENED 197
Query: 950 GGKETKMDLMVMENLFYNR-KIFRIYDLKGSARSRYNPNTSGKDKV-----LLDMNLLET 1111
++VM N+F +R + R YDLKGS SR S K+KV L DM+ L
Sbjct: 198 S------YMLVMRNMFSHRLPVHRKYDLKGSLVSR---EASDKEKVKELPTLKDMDFLN- 247
Query: 1112 LRTEPIFLGSKAKRSLERAIWNDTNFLASVDVMDYSLLVGFDE 1240
+ + +++G + K+ + D FL + +MDYSLL+G +
Sbjct: 248 -KNQKVYIGEEEKKVFLEKLKRDVEFLVQLKIMDYSLLLGIHD 289
>sp|O88370|PI42C_RAT Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma
OS=Rattus norvegicus GN=Pip4k2c PE=1 SV=1
Length = 420
Score = 62 bits (149), Expect = 1e-008
Identities = 47/163 (28%), Positives = 78/163 (47%), Gaps = 22/163 (13%)
Frame = +2
Query: 785 DERFIIKQ-----VVKTELDSFEDFAPEYFKYMKESLSSGSPTCLAKILGIYQVSIKHSK 949
D RF+I + + + D Y + + T L + LG+Y+VS+++
Sbjct: 138 DGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVENED 197
Query: 950 GGKETKMDLMVMENLFYNR-KIFRIYDLKGSARSRYNPNTSGKDKV-----LLDMNLLET 1111
++VM N+F +R + R YDLKGS SR S K+KV L DM+ L
Sbjct: 198 S------YMLVMRNMFSHRLPVHRKYDLKGSLVSR---EASDKEKVKELPTLKDMDFLN- 247
Query: 1112 LRTEPIFLGSKAKRSLERAIWNDTNFLASVDVMDYSLLVGFDE 1240
+ + +++G + K+ + D FL + +MDYSLL+G +
Sbjct: 248 -KNQKVYIGEEEKKVFLEKLKRDVEFLVQLKIMDYSLLLGIHD 289
>sp|Q8TBX8|PI42C_HUMAN Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma
OS=Homo sapiens GN=PIP4K2C PE=1 SV=2
Length = 421
Score = 61 bits (147), Expect = 2e-008
Identities = 47/163 (28%), Positives = 77/163 (47%), Gaps = 22/163 (13%)
Frame = +2
Query: 785 DERFIIKQ-----VVKTELDSFEDFAPEYFKYMKESLSSGSPTCLAKILGIYQVSIKHSK 949
D RF+I + + + D Y + + T L + LG+Y+VS+ +
Sbjct: 138 DGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNED 197
Query: 950 GGKETKMDLMVMENLFYNR-KIFRIYDLKGSARSRYNPNTSGKDKV-----LLDMNLLET 1111
++VM N+F +R + R YDLKGS SR S K+KV L DM+ L
Sbjct: 198 S------YMLVMRNMFSHRLPVHRKYDLKGSLVSR---EASDKEKVKELPTLKDMDFLN- 247
Query: 1112 LRTEPIFLGSKAKRSLERAIWNDTNFLASVDVMDYSLLVGFDE 1240
+ + +++G + K+ + D FL + +MDYSLL+G +
Sbjct: 248 -KNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHD 289
>sp|Q0P5F7|PI42C_BOVIN Phosphatidylinositol-5-phosphate 4-kinase type-2 gamma
OS=Bos taurus GN=PIP4K2C PE=2 SV=1
Length = 421
Score = 60 bits (145), Expect = 3e-008
Identities = 47/163 (28%), Positives = 76/163 (46%), Gaps = 22/163 (13%)
Frame = +2
Query: 785 DERFIIKQ-----VVKTELDSFEDFAPEYFKYMKESLSSGSPTCLAKILGIYQVSIKHSK 949
D RF+I + + + D Y + + T L + LG+Y+VS+
Sbjct: 138 DGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDSED 197
Query: 950 GGKETKMDLMVMENLFYNR-KIFRIYDLKGSARSRYNPNTSGKDKV-----LLDMNLLET 1111
++VM N+F +R + R YDLKGS SR S K+KV L DM+ L
Sbjct: 198 S------YMLVMRNMFSHRLPVHRKYDLKGSLVSR---EASDKEKVKELPTLKDMDFLN- 247
Query: 1112 LRTEPIFLGSKAKRSLERAIWNDTNFLASVDVMDYSLLVGFDE 1240
+ + +++G + K+ + D FL + +MDYSLL+G +
Sbjct: 248 -KNQKVYIGEEEKKVFLEKLKRDVEFLVQLKIMDYSLLLGIHD 289
>sp|Q55GN6|Y7588_DICDI Probable phosphatidylinositol phosphate kinase
DDB_G0267588 OS=Dictyostelium discoideum GN=DDB_G0267588 PE=1 SV=1
Length = 719
Score = 55 bits (131), Expect = 1e-006
Identities = 42/128 (32%), Positives = 63/128 (49%), Gaps = 6/128 (4%)
Frame = +2
Query: 872 ESLSSGSPTCLAKILGIYQVSIKHSKGGKETKMDLMVMENLF-YNRKIFRIYDLKGSARS 1048
E + S + L + G+Y+V HS G++ + ++M NLF +KI YDLKGS
Sbjct: 458 EHIQSNPNSLLPRFFGLYRVK-PHS--GRQVR--FVIMGNLFPTKKKIHERYDLKGSVVG 512
Query: 1049 RYNPNTSGKDKVLLDMNLLETLRTEPIFLGSKAKRSLERAIWNDTNFLASVDVMDYSLLV 1228
R K + ++ R + IFLG K+S I D L S+++MDYSLL+
Sbjct: 513 REASVDEKKSDSVTFKDIDFRNRKQKIFLGPGKKQSFIDQIKRDCKLLQSLNIMDYSLLI 572
Query: 1229 GFDEERKE 1252
G +E
Sbjct: 573 GIHYPHRE 580
>sp|P78356|PI42B_HUMAN Phosphatidylinositol-5-phosphate 4-kinase type-2 beta
OS=Homo sapiens GN=PIP4K2B PE=1 SV=1
Length = 416
Score = 53 bits (126), Expect = 5e-006
Identities = 45/138 (32%), Positives = 71/138 (51%), Gaps = 18/138 (13%)
Frame = +2
Query: 860 KYMKESLSSGSPTCLAKILGIYQVSIKHSKGGKETKMDLMVMENLFYNR-KIFRIYDLKG 1036
KY + + T L + LG+Y++++ G ET M +V N+F +R + R YDLKG
Sbjct: 166 KYHQFIVECHGNTLLPQFLGMYRLTV----DGVETYM--VVTRNVFSHRLTVHRKYDLKG 219
Query: 1037 SARSRYNPNTSGKDK-----VLLDMNLLETLRTEPIFLGSKAKRSLERAIWNDTNFLASV 1201
S +R S K+K D + L + + +G ++K++ + D FLA +
Sbjct: 220 STVAR---EASDKEKAKDLPTFKDNDFLN--EGQKLHVGEESKKNFLEKLKRDVEFLAQL 274
Query: 1202 DVMDYSLLVGF-DEERKE 1252
+MDYSLLVG D +R E
Sbjct: 275 KIMDYSLLVGIHDVDRAE 292
>sp|Q80XI4|PI42B_MOUSE Phosphatidylinositol-5-phosphate 4-kinase type-2 beta
OS=Mus musculus GN=Pip4k2b PE=1 SV=1
Length = 416
Score = 53 bits (126), Expect = 5e-006
Identities = 45/138 (32%), Positives = 71/138 (51%), Gaps = 18/138 (13%)
Frame = +2
Query: 860 KYMKESLSSGSPTCLAKILGIYQVSIKHSKGGKETKMDLMVMENLFYNR-KIFRIYDLKG 1036
KY + + T L + LG+Y++++ G ET M +V N+F +R + R YDLKG
Sbjct: 166 KYHQFIVECHGNTLLPQFLGMYRLTV----DGVETYM--VVTRNVFSHRLTVHRKYDLKG 219
Query: 1037 SARSRYNPNTSGKDK-----VLLDMNLLETLRTEPIFLGSKAKRSLERAIWNDTNFLASV 1201
S +R S K+K D + L + + +G ++K++ + D FLA +
Sbjct: 220 STVAR---EASDKEKAKDLPTFKDNDFLN--EGQKLHVGEESKKNFLEKLKRDVEFLAQL 274
Query: 1202 DVMDYSLLVGF-DEERKE 1252
+MDYSLLVG D +R E
Sbjct: 275 KIMDYSLLVGIHDVDRAE 292
>sp|O88377|PI42B_RAT Phosphatidylinositol-5-phosphate 4-kinase type-2 beta
OS=Rattus norvegicus GN=Pip4k2b PE=1 SV=1
Length = 416
Score = 52 bits (124), Expect = 9e-006
Identities = 45/138 (32%), Positives = 71/138 (51%), Gaps = 18/138 (13%)
Frame = +2
Query: 860 KYMKESLSSGSPTCLAKILGIYQVSIKHSKGGKETKMDLMVMENLFYNR-KIFRIYDLKG 1036
KY + + T L + LG+Y++++ G ET M +V N+F +R + R YDLKG
Sbjct: 166 KYHQFIVECHGNTLLPQFLGMYRLTV----DGVETYM--VVTRNVFSHRLTVHRKYDLKG 219
Query: 1037 SARSRYNPNTSGKDK-----VLLDMNLLETLRTEPIFLGSKAKRSLERAIWNDTNFLASV 1201
S +R S K+K D + L + + +G ++K++ + D FLA +
Sbjct: 220 STVAR---EASDKEKAKDLPTFKDNDFLN--EGQKLRVGEESKKNFLEKLKRDVEFLAQL 274
Query: 1202 DVMDYSLLVGF-DEERKE 1252
+MDYSLLVG D +R E
Sbjct: 275 KIMDYSLLVGIHDVDRAE 292
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 116,323,427,680
Number of Sequences: 518415
Number of Extensions: 116323427680
Number of Successful Extensions: 743337835
Number of sequences better than 0.0: 0
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