BLASTX 7.6.2
Query= UN28003 /QuerySize=1868
(1867 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O65595|KPYC_ARATH Probable pyruvate kinase, cytosolic isozyme... 875 3e-253
sp|Q42954|KPYC_TOBAC Pyruvate kinase, cytosolic isozyme OS=Nicot... 851 6e-246
sp|Q42806|KPYC_SOYBN Pyruvate kinase, cytosolic isozyme OS=Glyci... 775 3e-223
sp|P22200|KPYC_SOLTU Pyruvate kinase, cytosolic isozyme OS=Solan... 753 2e-216
sp|O44006|KPYK_EIMTE Pyruvate kinase OS=Eimeria tenella GN=PYK P... 427 2e-118
sp|Q92122|KPYK_XENLA Pyruvate kinase muscle isozyme OS=Xenopus l... 405 8e-112
sp|Q12669|KPYK_ASPNG Pyruvate kinase OS=Aspergillus niger GN=pki... 394 1e-108
sp|P14618|KPYM_HUMAN Pyruvate kinase isozymes M1/M2 OS=Homo sapi... 394 1e-108
sp|P52480|KPYM_MOUSE Pyruvate kinase isozymes M1/M2 OS=Mus muscu... 394 2e-108
sp|Q5NVN0|KPYM_PONAB Pyruvate kinase isozyme M1 OS=Pongo abelii ... 393 4e-108
sp|P00548|KPYK_CHICK Pyruvate kinase muscle isozyme OS=Gallus ga... 392 7e-108
sp|P22360|KPYK_EMENI Pyruvate kinase OS=Emericella nidulans GN=p... 391 2e-107
sp|P11980|KPYM_RAT Pyruvate kinase isozymes M1/M2 OS=Rattus norv... 391 2e-107
sp|P11979|KPYM_FELCA Pyruvate kinase isozyme M1 OS=Felis catus G... 387 1e-106
sp|P11974|KPYM_RABIT Pyruvate kinase isozymes M1/M2 OS=Oryctolag... 383 3e-105
sp|P30615|KPYK1_TRYBB Pyruvate kinase 1 OS=Trypanosoma brucei br... 382 4e-105
sp|Q29536|KPYR_CANFA Pyruvate kinase isozyme R (Fragment) OS=Can... 382 7e-105
sp|P30616|KPYK2_TRYBB Pyruvate kinase 2 OS=Trypanosoma brucei br... 379 4e-104
sp|O94122|KPYK_AGABI Pyruvate kinase OS=Agaricus bisporus GN=pki... 377 1e-103
sp|Q7RVA8|KPYK_NEUCR Pyruvate kinase OS=Neurospora crassa GN=pyk... 372 4e-102
>sp|O65595|KPYC_ARATH Probable pyruvate kinase, cytosolic isozyme OS=Arabidopsis
thaliana GN=At4g26390 PE=2 SV=1
Length = 497
Score = 875 bits (2259), Expect = 3e-253
Identities = 437/495 (88%), Positives = 473/495 (95%)
Frame = +2
Query: 137 IEQKPKTKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMLNT 316
+EQ+PKTKIVCTLGPASRSV MVEKLL AGM+VARFNFSHGS+EYHQETLDNLRQAMLNT
Sbjct: 3 MEQRPKTKIVCTLGPASRSVPMVEKLLMAGMSVARFNFSHGSYEYHQETLDNLRQAMLNT 62
Query: 317 GILCAVMLDTKGPEIRTGFLKDGKPIQLTQGQEITVSTDYDLQGDEETICMSYKKLAEDV 496
G+LCAVMLDTKGPEIRTGFLKDGKPIQL QGQEIT+STDYDL+GDE+TICMSYKKLA+DV
Sbjct: 63 GMLCAVMLDTKGPEIRTGFLKDGKPIQLKQGQEITISTDYDLKGDEKTICMSYKKLAQDV 122
Query: 497 NPGMVILCADGTISLLVLSCDTENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDK 676
NPGMVILCADGTISL VLSCD E GTVRCRCEN++MLGERKNVNLPGVVVDLPTLTEKDK
Sbjct: 123 NPGMVILCADGTISLKVLSCDKEKGTVRCRCENTSMLGERKNVNLPGVVVDLPTLTEKDK 182
Query: 677 EDIMKWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVANFDDILV 856
+DI++WGVPNQIDMIALSFVRKGSDLVQVRKLLG HAK ILLMSKVENQEGVANFDDIL+
Sbjct: 183 QDILEWGVPNQIDMIALSFVRKGSDLVQVRKLLGKHAKTILLMSKVENQEGVANFDDILI 242
Query: 857 NSDAFMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEA 1036
NSDAFMIARGDLGMEIPIEKIFLAQKVMIYKCN GKPVVTATQMLESMIKSPRPTRAEA
Sbjct: 243 NSDAFMIARGDLGMEIPIEKIFLAQKVMIYKCNFMGKPVVTATQMLESMIKSPRPTRAEA 302
Query: 1037 TGVANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIMQYSPVP 1216
T VANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGD+FK IM ++ VP
Sbjct: 303 TDVANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDIFKRIMLHAAVP 362
Query: 1217 MSPLESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSVVVPEMKTDFFDW 1396
MSP+ESLASSAVRTA S+RATL+MVLTRGGSTARLVAKYRPG+PILSVVVPE+ +D FDW
Sbjct: 363 MSPMESLASSAVRTATSSRATLMMVLTRGGSTARLVAKYRPGIPILSVVVPEITSDSFDW 422
Query: 1397 SCSDESPARHSLIFRGLIPVLYAGSARASHDESTEEAIEFATQHGKEKRLCKTGDSVVAL 1576
+CS+E+PARHSLI+RGL+PVLYAGSARAS DESTEE +EFA+++GK+K+LCKTGDSVVAL
Sbjct: 423 ACSNEAPARHSLIYRGLVPVLYAGSARASIDESTEETLEFASEYGKKKQLCKTGDSVVAL 482
Query: 1577 LRVGNASLIKILTVK 1621
R GNA +IKILTVK
Sbjct: 483 FRTGNAIVIKILTVK 497
>sp|Q42954|KPYC_TOBAC Pyruvate kinase, cytosolic isozyme OS=Nicotiana tabacum
PE=2 SV=1
Length = 508
Score = 851 bits (2196), Expect = 6e-246
Identities = 423/493 (85%), Positives = 460/493 (93%)
Frame = +2
Query: 143 QKPKTKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMLNTGI 322
++PKTKIVCTLGPASRSV M+EKLLRAGMNVARFNFSHGSH+YHQET+DNLRQAM +TGI
Sbjct: 16 KRPKTKIVCTLGPASRSVPMIEKLLRAGMNVARFNFSHGSHDYHQETIDNLRQAMESTGI 75
Query: 323 LCAVMLDTKGPEIRTGFLKDGKPIQLTQGQEITVSTDYDLQGDEETICMSYKKLAEDVNP 502
LCAVMLDTKGPEIRTGFLKD KP+QL QGQEIT+STDY ++GDE ICMSYKKLAEDV P
Sbjct: 76 LCAVMLDTKGPEIRTGFLKDAKPVQLKQGQEITISTDYSIKGDESMICMSYKKLAEDVKP 135
Query: 503 GMVILCADGTISLLVLSCDTENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKED 682
VILCADG I+ VLSCD ENG RCRCEN+A+LGERKNVNLPGV+VDLPTLT+KDK+D
Sbjct: 136 QSVILCADGQITFTVLSCDKENGLDRCRCENTAVLGERKNVNLPGVIVDLPTLTDKDKDD 195
Query: 683 IMKWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVANFDDILVNS 862
I+ WGVPN IDMIALSFVRKGSDLV+VRKLLG+HAKNILLMSKVENQEGVANFDDIL+NS
Sbjct: 196 ILNWGVPNHIDMIALSFVRKGSDLVEVRKLLGEHAKNILLMSKVENQEGVANFDDILLNS 255
Query: 863 DAFMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEATG 1042
DAFM+ARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEAT
Sbjct: 256 DAFMVARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEATD 315
Query: 1043 VANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIMQYSPVPMS 1222
VANAVLDGTDCVMLSGETAAGAYP+LAV TMAKIC+EAEST+DY DVFK IM +PVPMS
Sbjct: 316 VANAVLDGTDCVMLSGETAAGAYPDLAVGTMAKICIEAESTIDYPDVFKRIMSNAPVPMS 375
Query: 1223 PLESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSVVVPEMKTDFFDWSC 1402
PLESLASSAVRTANSA+A LI+VLTRGGSTA+LVAKYRPGMPILSVVVPE+KTD FDW+C
Sbjct: 376 PLESLASSAVRTANSAKAALILVLTRGGSTAKLVAKYRPGMPILSVVVPEIKTDSFDWTC 435
Query: 1403 SDESPARHSLIFRGLIPVLYAGSARASHDESTEEAIEFATQHGKEKRLCKTGDSVVALLR 1582
SDESPARHSLIFRGL+PVL+AGSARASH+ESTEEA++FA QH K K LCK GDSVVAL R
Sbjct: 436 SDESPARHSLIFRGLVPVLHAGSARASHEESTEEALDFALQHAKTKGLCKQGDSVVALHR 495
Query: 1583 VGNASLIKILTVK 1621
VG AS+IKI+TVK
Sbjct: 496 VGTASVIKIVTVK 508
>sp|Q42806|KPYC_SOYBN Pyruvate kinase, cytosolic isozyme OS=Glycine max PE=2
SV=1
Length = 511
Score = 775 bits (2000), Expect = 3e-223
Identities = 386/491 (78%), Positives = 438/491 (89%)
Frame = +2
Query: 149 PKTKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMLNTGILC 328
PKTKIVCTLGPASRSVEM EKLLRAGMNVARFNFSHG+H+YHQETL+NL+ AM NTGILC
Sbjct: 21 PKTKIVCTLGPASRSVEMTEKLLRAGMNVARFNFSHGTHDYHQETLNNLKTAMHNTGILC 80
Query: 329 AVMLDTKGPEIRTGFLKDGKPIQLTQGQEITVSTDYDLQGDEETICMSYKKLAEDVNPGM 508
AVMLDTKGPEIRTGFLKDGKPIQL +GQE+T++TDYD++GD E I MSYKKL + PG
Sbjct: 81 AVMLDTKGPEIRTGFLKDGKPIQLKEGQEVTITTDYDIKGDPEMISMSYKKLPVHLKPGN 140
Query: 509 VILCADGTISLLVLSCDTENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKEDIM 688
ILC+DGTI+L VLSCD + GTVRCRCEN+A LGERKNVNLPGVVVDLPTLTEKDKEDI+
Sbjct: 141 TILCSDGTITLTVLSCDPDAGTVRCRCENTATLGERKNVNLPGVVVDLPTLTEKDKEDIL 200
Query: 689 KWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVANFDDILVNSDA 868
WGVPN+IDMIALSFVRKGSDLV VRK+LG HAKNI LMSKVENQEGV NFD+IL +DA
Sbjct: 201 GWGVPNKIDMIALSFVRKGSDLVNVRKVLGPHAKNIQLMSKVENQEGVLNFDEILRETDA 260
Query: 869 FMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEATGVA 1048
FM+ARGDLGMEIP+EKIFLAQK+MIYKCN+ GKPVVTATQMLESMIKSPRPTRAEAT VA
Sbjct: 261 FMVARGDLGMEIPVEKIFLAQKMMIYKCNLVGKPVVTATQMLESMIKSPRPTRAEATDVA 320
Query: 1049 NAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIMQYSPVPMSPL 1228
NAVLDGTDCVMLSGE+AAGAYPELAV+ MA+IC+EAES+LDYG +FK +++ +P+PMSPL
Sbjct: 321 NAVLDGTDCVMLSGESAAGAYPELAVKIMARICIEAESSLDYGAIFKEMIRSTPLPMSPL 380
Query: 1229 ESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSVVVPEMKTDFFDWSCSD 1408
ESLASSAVRTAN A+A LI+VLTRGGSTA+LVAKYRP +PILSVVVP + TD FDW+CSD
Sbjct: 381 ESLASSAVRTANKAKAKLIVVLTRGGSTAKLVAKYRPAVPILSVVVPVLSTDSFDWTCSD 440
Query: 1409 ESPARHSLIFRGLIPVLYAGSARASHDESTEEAIEFATQHGKEKRLCKTGDSVVALLRVG 1588
E+PARHSLI+RGLIP+L GSA+A+ ESTE +E A + E+ LCK GD+VVAL R+G
Sbjct: 441 ETPARHSLIYRGLIPILGEGSAKATDAESTEVILEAALKSATERALCKPGDAVVALHRIG 500
Query: 1589 NASLIKILTVK 1621
AS+IKI VK
Sbjct: 501 AASVIKICIVK 511
>sp|P22200|KPYC_SOLTU Pyruvate kinase, cytosolic isozyme OS=Solanum tuberosum
PE=2 SV=1
Length = 510
Score = 753 bits (1942), Expect = 2e-216
Identities = 379/491 (77%), Positives = 431/491 (87%)
Frame = +2
Query: 149 PKTKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMLNTGILC 328
PKTKIVCTLGP+SR+V M+EKLLRAGMNVARFNFSHG+HEYHQETLDNL+ AM NT ILC
Sbjct: 20 PKTKIVCTLGPSSRTVPMLEKLLRAGMNVARFNFSHGTHEYHQETLDNLKIAMQNTQILC 79
Query: 329 AVMLDTKGPEIRTGFLKDGKPIQLTQGQEITVSTDYDLQGDEETICMSYKKLAEDVNPGM 508
AVMLDTKGPEIRTGFL DGKPIQL +GQEITVSTDY ++G+EE I MSYKKL D+ PG
Sbjct: 80 AVMLDTKGPEIRTGFLTDGKPIQLKEGQEITVSTDYTIKGNEEMISMSYKKLVMDLKPGN 139
Query: 509 VILCADGTISLLVLSCDTENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKEDIM 688
ILCADGTI+L VLSCD +GTVRCRCEN+A LGERKNVNLPGVVVDLPTLTEKDKEDI+
Sbjct: 140 TILCADGTITLTVLSCDPPSGTVRCRCENTATLGERKNVNLPGVVVDLPTLTEKDKEDIL 199
Query: 689 KWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVANFDDILVNSDA 868
+WGVPN IDMIALSFVRKGSDLV VRK+LG HAK I LMSKVENQEGV NFD+IL +D+
Sbjct: 200 EWGVPNNIDMIALSFVRKGSDLVNVRKVLGPHAKRIQLMSKVENQEGVINFDEILRETDS 259
Query: 869 FMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEATGVA 1048
FM+ARGDLGMEIP+EKIFLAQK+MIYKCN+ GK VVTATQMLESMIKSP PTRAEAT VA
Sbjct: 260 FMVARGDLGMEIPVEKIFLAQKMMIYKCNLAGKAVVTATQMLESMIKSPAPTRAEATDVA 319
Query: 1049 NAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIMQYSPVPMSPL 1228
NAVLDGTDCVMLSGE+AAGAYPELAV+ M++IC+EAES+LD +FK +++ +P+PMSPL
Sbjct: 320 NAVLDGTDCVMLSGESAAGAYPELAVKIMSRICIEAESSLDNEAIFKEMIRCTPLPMSPL 379
Query: 1229 ESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSVVVPEMKTDFFDWSCSD 1408
ESLASSAVRTAN ARA LI+VLTRGGSTA+LVAKYRP +PILSVVVP + TD FDWS SD
Sbjct: 380 ESLASSAVRTANKARAKLIVVLTRGGSTAKLVAKYRPAVPILSVVVPVLTTDSFDWSISD 439
Query: 1409 ESPARHSLIFRGLIPVLYAGSARASHDESTEEAIEFATQHGKEKRLCKTGDSVVALLRVG 1588
E+PARHSL++RGLIP+L GSA+A+ ESTE +E A + + LCK GD+VVAL R+G
Sbjct: 440 ETPARHSLVYRGLIPLLGEGSAKATDSESTEVILEAALKSAVTRGLCKPGDAVVALHRIG 499
Query: 1589 NASLIKILTVK 1621
+AS+IKI VK
Sbjct: 500 SASVIKICVVK 510
>sp|O44006|KPYK_EIMTE Pyruvate kinase OS=Eimeria tenella GN=PYK PE=2 SV=1
Length = 531
Score = 427 bits (1097), Expect = 2e-118
Identities = 218/408 (53%), Positives = 285/408 (69%), Gaps = 3/408 (0%)
Frame = +2
Query: 152 KTKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAM-LNTGILC 328
+TKIVCT+GP+ V+ + +L+ AGMNV R NFSHG HE H + NL++A+ G
Sbjct: 57 RTKIVCTMGPSCWDVDKMVQLIDAGMNVCRLNFSHGDHEAHGRVVKNLQEALKQRPGKRV 116
Query: 329 AVMLDTKGPEIRTGFLKDGKPIQLTQGQEITVSTDYDLQGDEETICMSYKKLAEDVNPGM 508
A++LDTKGPEIRTG L+ KPI+L G + + TDY G++ I SY+KL V PG
Sbjct: 117 ALLLDTKGPEIRTGMLEGDKPIELHAGDMLKIVTDYSFVGNKSCIACSYEKLPSSVKPGN 176
Query: 509 VILCADGTISLLVLSCDTENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKEDIM 688
IL ADG++S+ V+ C + V R N A++G +KN+NLPGV VDLP + EKDK DI+
Sbjct: 177 TILIADGSLSVEVVECGKD--YVMTRVMNPAIIGNKKNMNLPGVKVDLPVIGEKDKNDIL 234
Query: 689 KWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVANFDDILVNSDA 868
+G+P + IA SFV+ D+ +R +LG +NI ++ K+EN EG+ NFD+IL +D
Sbjct: 235 NFGIPMGCNFIAASFVQSADDVRYIRSILGTKGRNIKIIPKIENVEGLLNFDEILQEADG 294
Query: 869 FMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEATGVA 1048
MIARGDLGMEIP EK+FLAQK+MI KCN+ GKPV+TATQMLESM K+PRPTRAEA VA
Sbjct: 295 IMIARGDLGMEIPPEKVFLAQKMMISKCNVAGKPVITATQMLESMTKNPRPTRAEAADVA 354
Query: 1049 NAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIMQYSPVPMSPL 1228
NAVLDGTDCVMLSGETA G++P AV M+++C EAE +DY VF+ Q + P+
Sbjct: 355 NAVLDGTDCVMLSGETANGSFPVQAVTVMSRVCFEAEGCIDYQQVFRATCQATMTPIDTQ 414
Query: 1229 ESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSVVVPE 1372
E++A +AV TA S A+LI+ LT G TARL+AKYRP PIL++ E
Sbjct: 415 EAVARAAVETAQSINASLILALTETGRTARLIAKYRPMQPILALSASE 462
>sp|Q92122|KPYK_XENLA Pyruvate kinase muscle isozyme OS=Xenopus laevis GN=pkm
PE=2 SV=1
Length = 527
Score = 405 bits (1039), Expect = 8e-112
Identities = 224/486 (46%), Positives = 307/486 (63%), Gaps = 30/486 (6%)
Frame = +2
Query: 155 TKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMLNTGI---- 322
T I+CT+GPASRSVEM+++++++GMN+AR NFSHG+HEYH T+ N+R+A +
Sbjct: 41 TGIICTIGPASRSVEMLKEMIKSGMNIARLNFSHGTHEYHAGTIKNVREATESLASNPIH 100
Query: 323 --LCAVMLDTKGPEIRTGFLKDG--KPIQLTQGQEITVSTDYDLQG--DEETICMSYKKL 484
AV LDTKGPEIRTG +K ++L +G + ++ D Q DE + + YK L
Sbjct: 101 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATMRITLDDAFQENCDENVLWVDYKNL 160
Query: 485 AEDVNPGMVILCADGTISLLVLSCDTENGTVRC--RCENSAMLGERKNVNLPGVVVDLPT 658
+ V PG I DG ISLLV E G C EN MLG +K VNLPG VDLP
Sbjct: 161 TKVVKPGSKIYVDDGLISLLV----KEIGPDFCVTEIENGGMLGSKKGVNLPGAAVDLPA 216
Query: 659 LTEKDKEDIMKWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVAN 838
++ KD +D +++GV +DM+ SF+RK +D+ +VR++LG+ KNI ++SK+EN EGV
Sbjct: 217 VSSKDIQD-LQFGVEQDVDMVFASFIRKAADVHEVREVLGEKGKNIKIISKIENHEGVRR 275
Query: 839 FDDILVNSDAFMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPR 1018
FD+IL SD M+ARGDLG+EIP EK+FLAQK+MI +CN GKPV+ ATQMLESMIK PR
Sbjct: 276 FDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPR 335
Query: 1019 PTRAEATGVANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIM 1198
PTRAE + VANAVLDG DC+MLSGETA G YP AVR I EAE+ + + +F+ +
Sbjct: 336 PTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIAREAEAAIFHRQLFEELR 395
Query: 1199 QYSPVPMSPLESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSVVVPEMK 1378
+ SP+ P E+ A AV + + I+VLT+ G +A L+++YRP PI+SV
Sbjct: 396 RVSPLTRDPTEATAVGAVEASFKCSSGAIIVLTKSGRSAHLLSRYRPRAPIISVT----- 450
Query: 1379 TDFFDWSCSDESPARHSLIFRGLIPVLYAGSARASHDESTEEAIEFATQHGKEKRLCKTG 1558
+ AR + ++RG+ PVLY + + E + + FA GK + K+G
Sbjct: 451 --------RNGQTARQAHLYRGIFPVLYREAVHEAWAEDVDSRVNFAMDIGKARGFFKSG 502
Query: 1559 DSVVAL 1576
D V+ L
Sbjct: 503 DVVIVL 508
>sp|Q12669|KPYK_ASPNG Pyruvate kinase OS=Aspergillus niger GN=pkiA PE=3 SV=1
Length = 526
Score = 394 bits (1011), Expect = 1e-108
Identities = 202/406 (49%), Positives = 278/406 (68%), Gaps = 5/406 (1%)
Frame = +2
Query: 152 KTKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQ-AMLNTGILC 328
+T I+ T+GP + SVE + L AG+NV R NFSHGS++YHQ +DN R+ A G
Sbjct: 34 RTSIIGTIGPKTNSVEKINSLRTAGLNVVRMNFSHGSYQYHQSVIDNAREAAKTQVGRPL 93
Query: 329 AVMLDTKGPEIRTGFLKDGKPIQLTQGQEITVSTD--YDLQGDEETICMSYKKLAEDVNP 502
A+ LDTKGPEIRTG D K I + QG E+ ++TD Y D++ + + YK + + ++P
Sbjct: 94 AIALDTKGPEIRTGNTPDDKDIPIKQGHELNITTDEQYATASDDKNMYLDYKNITKVISP 153
Query: 503 GMVILCADGTISLLVLSCDTENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKED 682
G +I DG +S VL ++ T+R RC N+ + RK VNLPG VDLP L+EKD D
Sbjct: 154 GKLIYVDDGILSFEVLEV-VDDKTIRVRCLNNGNISSRKGVNLPGTDVDLPALSEKDIAD 212
Query: 683 IMKWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVANFDDILVNS 862
+K+GV N++DM+ SF+R+GSD+ +R++LG+ K I +++K+ENQ+GV NFD+IL +
Sbjct: 213 -LKFGVRNKVDMVFASFIRRGSDIRHIREVLGEEGKEIQIIAKIENQQGVNNFDEILEET 271
Query: 863 DAFMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEATG 1042
D M+ARGDLG+EIP K+F+AQK+MI KCNI+GKPV+ ATQMLESM +PRPTRAE +
Sbjct: 272 DGVMVARGDLGIEIPAPKVFIAQKMMIAKCNIKGKPVICATQMLESMTYNPRPTRAEVSD 331
Query: 1043 VANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIMQYSPVPMS 1222
VANAVLDG DCVMLSGETA G YP AV+ M++ C+ AE + + +VF + +P P
Sbjct: 332 VANAVLDGADCVMLSGETAKGNYPNEAVKMMSETCLLAEVAIPHFNVFDELRNLAPRPTD 391
Query: 1223 PLESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSV 1360
+ES+A +AV + A I+VLT G TAR ++KYRP PI+ V
Sbjct: 392 TVESIAMAAVSASLELNAGAIVVLTTSGKTARYLSKYRPVCPIVMV 437
>sp|P14618|KPYM_HUMAN Pyruvate kinase isozymes M1/M2 OS=Homo sapiens GN=PKM2
PE=1 SV=4
Length = 531
Score = 394 bits (1011), Expect = 1e-108
Identities = 222/484 (45%), Positives = 304/484 (62%), Gaps = 26/484 (5%)
Frame = +2
Query: 155 TKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLR---QAMLNTGIL 325
T I+CT+GPASRSVE +++++++GMNVAR NFSHG+HEYH ET+ N+R ++ + IL
Sbjct: 45 TGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPIL 104
Query: 326 ---CAVMLDTKGPEIRTGFLKDG--KPIQLTQGQ--EITVSTDYDLQGDEETICMSYKKL 484
AV LDTKGPEIRTG +K ++L +G +IT+ Y + DE + + YK +
Sbjct: 105 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNI 164
Query: 485 AEDVNPGMVILCADGTISLLVLSCDTENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLT 664
+ V G I DG ISL V + + EN LG +K VNLPG VDLP ++
Sbjct: 165 CKVVEVGSKIYVDDGLISLQVKQKGAD--FLVTEVENGGSLGSKKGVNLPGAAVDLPAVS 222
Query: 665 EKDKEDIMKWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVANFD 844
EKD +D +K+GV +DM+ SF+RK SD+ +VRK+LG+ KNI ++SK+EN EGV FD
Sbjct: 223 EKDIQD-LKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFD 281
Query: 845 DILVNSDAFMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPT 1024
+IL SD M+ARGDLG+EIP EK+FLAQK+MI +CN GKPV+ ATQMLESMIK PRPT
Sbjct: 282 EILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPT 341
Query: 1025 RAEATGVANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIMQY 1204
RAE + VANAVLDG DC+MLSGETA G YP AVR I EAE+ + + +F+ + +
Sbjct: 342 RAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRL 401
Query: 1205 SPVPMSPLESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSVVVPEMKTD 1384
+P+ P E+ A AV + + I+VLT+ G +A VA+YRP PI++V
Sbjct: 402 APITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVT------- 454
Query: 1385 FFDWSCSDESPARHSLIFRGLIPVLYAGSARASHDESTEEAIEFATQHGKEKRLCKTGDS 1564
+ AR + ++RG+ PVL + + E + + FA GK + K GD
Sbjct: 455 ------RNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDV 508
Query: 1565 VVAL 1576
V+ L
Sbjct: 509 VIVL 512
>sp|P52480|KPYM_MOUSE Pyruvate kinase isozymes M1/M2 OS=Mus musculus GN=Pkm2
PE=1 SV=4
Length = 531
Score = 394 bits (1010), Expect = 2e-108
Identities = 224/486 (46%), Positives = 305/486 (62%), Gaps = 30/486 (6%)
Frame = +2
Query: 155 TKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQA---MLNTGIL 325
T I+CT+GPASRSVEM+++++++GMNVAR NFSHG+HEYH ET+ N+R+A + IL
Sbjct: 45 TGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVREATESFASDPIL 104
Query: 326 ---CAVMLDTKGPEIRTGFLKDG--KPIQLTQGQ--EITVSTDYDLQGDEETICMSYKKL 484
AV LDTKGPEIRTG +K ++L +G +IT+ Y + DE + + YK +
Sbjct: 105 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNI 164
Query: 485 AEDVNPGMVILCADGTISLLVLSCDTENGT--VRCRCENSAMLGERKNVNLPGVVVDLPT 658
+ V G I DG ISL V E G + EN LG +K VNLPG VDLP
Sbjct: 165 CKVVEVGSKIYVDDGLISLQV----KEKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPA 220
Query: 659 LTEKDKEDIMKWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVAN 838
++EKD +D +K+GV +DM+ SF+RK +D+ +VRK+LG+ KNI ++SK+EN EGV
Sbjct: 221 VSEKDIQD-LKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRR 279
Query: 839 FDDILVNSDAFMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPR 1018
FD+IL SD M+ARGDLG+EIP EK+FLAQK+MI +CN GKPV+ ATQMLESMIK PR
Sbjct: 280 FDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPR 339
Query: 1019 PTRAEATGVANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIM 1198
PTRAE + VANAVLDG DC+MLSGETA G YP AVR I EAE+ + + +F+ +
Sbjct: 340 PTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELR 399
Query: 1199 QYSPVPMSPLESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSVVVPEMK 1378
+ +P+ P E+ A AV + + I+VLT+ G +A VA+YRP PI++V
Sbjct: 400 RLAPITSDPTEAAAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVT----- 454
Query: 1379 TDFFDWSCSDESPARHSLIFRGLIPVLYAGSARASHDESTEEAIEFATQHGKEKRLCKTG 1558
+ AR + ++RG+ PVL + + E + + A GK + K G
Sbjct: 455 --------RNPQTARQAHLYRGIFPVLCKDAVLNAWAEDVDLRVNLAMDVGKARGFFKKG 506
Query: 1559 DSVVAL 1576
D V+ L
Sbjct: 507 DVVIVL 512
>sp|Q5NVN0|KPYM_PONAB Pyruvate kinase isozyme M1 OS=Pongo abelii GN=PKM2 PE=2
SV=3
Length = 531
Score = 393 bits (1007), Expect = 4e-108
Identities = 221/484 (45%), Positives = 304/484 (62%), Gaps = 26/484 (5%)
Frame = +2
Query: 155 TKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLR---QAMLNTGIL 325
T I+CT+GPASRSVE +++++++GMNVAR NFSHG+HEYH ET+ N+R ++ + IL
Sbjct: 45 TGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPIL 104
Query: 326 ---CAVMLDTKGPEIRTGFLKDG--KPIQLTQGQ--EITVSTDYDLQGDEETICMSYKKL 484
AV LDTKGPEIRTG +K ++L +G +IT+ Y + DE + + YK +
Sbjct: 105 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNI 164
Query: 485 AEDVNPGMVILCADGTISLLVLSCDTENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLT 664
+ V G I DG ISL V + + EN LG +K VNLPG VDLP ++
Sbjct: 165 CKVVEVGSKIYVDDGLISLQVKQKGAD--FLLTEVENGGSLGSKKGVNLPGAAVDLPAVS 222
Query: 665 EKDKEDIMKWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVANFD 844
EKD +D +K+GV +DM+ SF+RK SD+ +VRK+LG+ KNI ++SK+EN EGV FD
Sbjct: 223 EKDIQD-LKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFD 281
Query: 845 DILVNSDAFMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPT 1024
+IL SD M+ARGDLG+EIP EK+FLAQK+MI +CN GKPV+ ATQMLESMIK PRPT
Sbjct: 282 EILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPT 341
Query: 1025 RAEATGVANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIMQY 1204
RAE +GVANAVLDG DC+MLSGETA G YP AVR I EAE+ + + +F+ +++
Sbjct: 342 RAEGSGVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELVRA 401
Query: 1205 SPVPMSPLESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSVVVPEMKTD 1384
S +E++A +V + A ++VLT G +A VA+YRP PI++V
Sbjct: 402 SSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVT------- 454
Query: 1385 FFDWSCSDESPARHSLIFRGLIPVLYAGSARASHDESTEEAIEFATQHGKEKRLCKTGDS 1564
+ AR + ++RG+ PVL + + E + + FA GK + K GD
Sbjct: 455 ------RNPQTARQAHLYRGIFPVLCKDPVQEAWAEDVDLRVNFAMNVGKARGFFKKGDV 508
Query: 1565 VVAL 1576
V+ L
Sbjct: 509 VIVL 512
>sp|P00548|KPYK_CHICK Pyruvate kinase muscle isozyme OS=Gallus gallus GN=PKM2
PE=2 SV=2
Length = 530
Score = 392 bits (1005), Expect = 7e-108
Identities = 216/484 (44%), Positives = 305/484 (63%), Gaps = 26/484 (5%)
Frame = +2
Query: 155 TKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMLN------T 316
T I+CT+GPASRSV+ +++++++GMNVAR NFSHG+HEYH+ T+ N+R+A + T
Sbjct: 44 TGIICTIGPASRSVDKLKEMIKSGMNVARLNFSHGTHEYHEGTIKNVREATESFASDPIT 103
Query: 317 GILCAVMLDTKGPEIRTGFLKDG--KPIQLTQGQEITVSTD--YDLQGDEETICMSYKKL 484
A+ LDTKGPEIRTG +K ++L +G + V+ D + DE + + YK L
Sbjct: 104 YRPVAIALDTKGPEIRTGLIKGSGTAEVELKKGAALKVTLDNAFMENCDENVLWVDYKNL 163
Query: 485 AEDVNPGMVILCADGTISLLVLSCDTENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLT 664
+ ++ G I DG ISLLV + V EN MLG +K VNLPG VDLP ++
Sbjct: 164 IKVIDVGSKIYVDDGLISLLVK--EKGKDFVMTEVENGGMLGSKKGVNLPGAAVDLPAVS 221
Query: 665 EKDKEDIMKWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVANFD 844
EKD +D +K+GV +DM+ SF+RK +D+ VRK+LG+ K+I ++SK+EN EGV FD
Sbjct: 222 EKDIQD-LKFGVEQNVDMVFASFIRKAADVHAVRKVLGEKGKHIKIISKIENHEGVRRFD 280
Query: 845 DILVNSDAFMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPT 1024
+I+ SD M+ARGDLG+EIP EK+FLAQK+MI +CN GKP++ ATQMLESMIK PRPT
Sbjct: 281 EIMEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPIICATQMLESMIKKPRPT 340
Query: 1025 RAEATGVANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIMQY 1204
RAE + VANAVLDG DC+MLSGETA G YP AVR I EAE+ + + F+ I+++
Sbjct: 341 RAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHAIAREAEAAMFHRQQFEEILRH 400
Query: 1205 SPVPMSPLESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSVVVPEMKTD 1384
S P +++A+ AV + A ++V+T G +A LV++YRP PI++V
Sbjct: 401 SVHHREPADAMAAGAVEASFKCLAAALIVMTESGRSAHLVSRYRPRAPIIAVT------- 453
Query: 1385 FFDWSCSDESPARHSLIFRGLIPVLYAGSARASHDESTEEAIEFATQHGKEKRLCKTGDS 1564
++ AR + ++RG+ PVL A + E + + GK + KTGD
Sbjct: 454 ------RNDQTARQAHLYRGVFPVLCKQPAHDAWAEDVDLRVNLGMNVGKARGFFKTGDL 507
Query: 1565 VVAL 1576
V+ L
Sbjct: 508 VIVL 511
>sp|P22360|KPYK_EMENI Pyruvate kinase OS=Emericella nidulans GN=pkiA PE=3 SV=2
Length = 526
Score = 391 bits (1002), Expect = 2e-107
Identities = 201/406 (49%), Positives = 278/406 (68%), Gaps = 5/406 (1%)
Frame = +2
Query: 152 KTKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQA-MLNTGILC 328
+T I+CT+GP + SVE + L RAG+NV R NFSHGS+EYHQ +D+ R+A G
Sbjct: 34 RTSIICTIGPKTNSVEKINALRRAGLNVVRMNFSHGSYEYHQSVIDHAREAEKQQAGRPV 93
Query: 329 AVMLDTKGPEIRTGFLKDGKPIQLTQGQEITVSTD--YDLQGDEETICMSYKKLAEDVNP 502
A+ LDTKGPEIRTG K I + G E+ +STD Y D++ + + YK + + ++
Sbjct: 94 AIALDTKGPEIRTGNTVGDKDIPIKAGHEMNISTDEQYATASDDQNMYVDYKNITKVISA 153
Query: 503 GMVILCADGTISLLVLSCDTENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKED 682
G +I DG +S VL ++ T+R RC N+ + RK VNLPG VDLP L+EKD D
Sbjct: 154 GKLIYVDDGILSFEVLEV-VDDKTLRVRCLNNGNISSRKGVNLPGTDVDLPALSEKDISD 212
Query: 683 IMKWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVANFDDILVNS 862
+K+GV N++DM+ SF+R+GSD+ +R++LG+ + I +++K+ENQ+GV NFD+IL +
Sbjct: 213 -LKFGVKNKVDMVFASFIRRGSDIRHIREVLGEEGREIQIIAKIENQQGVNNFDEILEET 271
Query: 863 DAFMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEATG 1042
D M+ARGDLG+EIP K+F+AQK+MI KCNI+GKPV+ ATQMLESM +PRPTRAE +
Sbjct: 272 DGVMVARGDLGIEIPAPKVFIAQKMMIAKCNIKGKPVICATQMLESMTYNPRPTRAEVSD 331
Query: 1043 VANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIMQYSPVPMS 1222
VANAVLDG DCVMLSGETA G YP AV M++ C+ AE + + +VF + +P P
Sbjct: 332 VANAVLDGADCVMLSGETAKGNYPCEAVTMMSETCLLAEVAIPHFNVFDELRNLAPRPTD 391
Query: 1223 PLESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSV 1360
+ES+A +AV + A I+VLT G+TAR+++KYRP PI+ V
Sbjct: 392 TVESIAMAAVSASLELNAGAIVVLTTSGNTARMISKYRPVCPIIMV 437
>sp|P11980|KPYM_RAT Pyruvate kinase isozymes M1/M2 OS=Rattus norvegicus GN=Pkm2
PE=1 SV=3
Length = 531
Score = 391 bits (1002), Expect = 2e-107
Identities = 223/486 (45%), Positives = 304/486 (62%), Gaps = 30/486 (6%)
Frame = +2
Query: 155 TKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLR---QAMLNTGIL 325
T I+CT+GPASRSVEM+++++++GMNVAR NFSHG+HEYH ET+ N+R ++ + IL
Sbjct: 45 TGIICTIGPASRSVEMLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPIL 104
Query: 326 ---CAVMLDTKGPEIRTGFLKDG--KPIQLTQGQ--EITVSTDYDLQGDEETICMSYKKL 484
AV LDTKGPEIRTG +K ++L +G +IT+ Y + DE + + YK +
Sbjct: 105 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNI 164
Query: 485 AEDVNPGMVILCADGTISLLVLSCDTENGT--VRCRCENSAMLGERKNVNLPGVVVDLPT 658
+ V G I DG ISL V E G + EN LG +K VNLPG VDLP
Sbjct: 165 CKVVEVGSKIYVDDGLISLQV----KEKGADYLVTEVENGGSLGSKKGVNLPGAAVDLPA 220
Query: 659 LTEKDKEDIMKWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVAN 838
++EKD +D +K+GV +DM+ SF+RK +D+ +VRK+LG+ KNI ++SK+EN EGV
Sbjct: 221 VSEKDIQD-LKFGVEQDVDMVFASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRR 279
Query: 839 FDDILVNSDAFMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPR 1018
FD+IL SD M+ARGDLG+EIP EK+FLAQK+MI +CN GKPV+ ATQMLESMIK PR
Sbjct: 280 FDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPR 339
Query: 1019 PTRAEATGVANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIM 1198
PTRAE + VANAVLDG DC+MLSGETA G YP AVR I EAE+ + + +F+ +
Sbjct: 340 PTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAVFHRLLFEELA 399
Query: 1199 QYSPVPMSPLESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSVVVPEMK 1378
+ S PLE++A +V + A ++VLT G +A VA+YRP PI++V
Sbjct: 400 RASSQSTDPLEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVT----- 454
Query: 1379 TDFFDWSCSDESPARHSLIFRGLIPVLYAGSARASHDESTEEAIEFATQHGKEKRLCKTG 1558
+ AR + ++RG+ PVL + + E + + A GK + K G
Sbjct: 455 --------RNPQTARQAHLYRGIFPVLCKDAVLDAWAEDVDLRVNLAMNVGKARGFFKKG 506
Query: 1559 DSVVAL 1576
D V+ L
Sbjct: 507 DVVIVL 512
>sp|P11979|KPYM_FELCA Pyruvate kinase isozyme M1 OS=Felis catus GN=PKM2 PE=1
SV=2
Length = 531
Score = 387 bits (994), Expect = 1e-106
Identities = 219/486 (45%), Positives = 302/486 (62%), Gaps = 30/486 (6%)
Frame = +2
Query: 155 TKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMLNTGI---- 322
T I+CT+GPASRSVE++++++++GMNVAR NFSHG+HEYH ET+ N+R A +
Sbjct: 45 TGIICTIGPASRSVEILKEMIKSGMNVARLNFSHGTHEYHAETIKNVRAATESFASDPIR 104
Query: 323 --LCAVMLDTKGPEIRTGFLKDG--KPIQLTQGQ--EITVSTDYDLQGDEETICMSYKKL 484
AV LDTKGPEIRTG +K ++L +G +IT+ Y + DE + + YK +
Sbjct: 105 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENVLWLDYKNI 164
Query: 485 AEDVNPGMVILCADGTISLLVLSCDTENGT--VRCRCENSAMLGERKNVNLPGVVVDLPT 658
+ V G + DG ISLLV E G + EN LG +K VNLPG VDLP
Sbjct: 165 CKVVEVGSKVYVDDGLISLLV----KEKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPA 220
Query: 659 LTEKDKEDIMKWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVAN 838
++EKD +D +K+GV +DM+ SF+RK SD+ +VRK+LG+ KNI ++SK+EN EGV
Sbjct: 221 VSEKDIQD-LKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKGKNIKIISKIENHEGVRR 279
Query: 839 FDDILVNSDAFMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPR 1018
FD+IL SD M+ARGDLG+EIP EK+FLAQK+MI +CN GKPV+ ATQMLESMIK PR
Sbjct: 280 FDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPR 339
Query: 1019 PTRAEATGVANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIM 1198
PTRAE + VANAVLDG DC+MLSGETA G YP AVR I EAE+ + + +F+ ++
Sbjct: 340 PTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELV 399
Query: 1199 QYSPVPMSPLESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSVVVPEMK 1378
+ S +E++A +V + A ++VLT G +A VA+YRP PI++V
Sbjct: 400 RGSSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVT----- 454
Query: 1379 TDFFDWSCSDESPARHSLIFRGLIPVLYAGSARASHDESTEEAIEFATQHGKEKRLCKTG 1558
+ AR + ++RG+ PV+ + + E + + A GK + K G
Sbjct: 455 --------RNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKHG 506
Query: 1559 DSVVAL 1576
D V+ L
Sbjct: 507 DVVIVL 512
>sp|P11974|KPYM_RABIT Pyruvate kinase isozymes M1/M2 OS=Oryctolagus cuniculus
GN=PKM2 PE=1 SV=4
Length = 531
Score = 383 bits (983), Expect = 3e-105
Identities = 215/484 (44%), Positives = 302/484 (62%), Gaps = 26/484 (5%)
Frame = +2
Query: 155 TKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLR---QAMLNTGIL 325
T I+CT+GPASRSVE +++++++GMNVAR NFSHG+HEYH ET+ N+R ++ + IL
Sbjct: 45 TGIICTIGPASRSVETLKEMIKSGMNVARMNFSHGTHEYHAETIKNVRTATESFASDPIL 104
Query: 326 ---CAVMLDTKGPEIRTGFLKDG--KPIQLTQGQ--EITVSTDYDLQGDEETICMSYKKL 484
AV LDTKGPEIRTG +K ++L +G +IT+ Y + DE + + YK +
Sbjct: 105 YRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNI 164
Query: 485 AEDVNPGMVILCADGTISLLVLSCDTENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLT 664
+ V+ G + DG ISL V + + EN LG +K VNLPG VDLP ++
Sbjct: 165 CKVVDVGSKVYVDDGLISLQVKQKGPD--FLVTEVENGGFLGSKKGVNLPGAAVDLPAVS 222
Query: 665 EKDKEDIMKWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVANFD 844
EKD +D +K+GV +DM+ SF+RK +D+ +VRK+LG+ KNI ++SK+EN EGV FD
Sbjct: 223 EKDIQD-LKFGVEQDVDMVFASFIRKAADVHEVRKILGEKGKNIKIISKIENHEGVRRFD 281
Query: 845 DILVNSDAFMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPT 1024
+IL SD M+ARGDLG+EIP EK+FLAQK++I +CN GKPV+ ATQMLESMIK PRPT
Sbjct: 282 EILEASDGIMVARGDLGIEIPAEKVFLAQKMIIGRCNRAGKPVICATQMLESMIKKPRPT 341
Query: 1025 RAEATGVANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIMQY 1204
RAE + VANAVLDG DC+MLSGETA G YP AVR I EAE+ + + +F+ + +
Sbjct: 342 RAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAMFHRKLFEELARS 401
Query: 1205 SPVPMSPLESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSVVVPEMKTD 1384
S +E++A +V + A ++VLT G +A VA+YRP PI++V
Sbjct: 402 SSHSTDLMEAMAMGSVEASYKCLAAALIVLTESGRSAHQVARYRPRAPIIAVT------- 454
Query: 1385 FFDWSCSDESPARHSLIFRGLIPVLYAGSARASHDESTEEAIEFATQHGKEKRLCKTGDS 1564
+ AR + ++RG+ PV+ + + E + + A GK + K GD
Sbjct: 455 ------RNHQTARQAHLYRGIFPVVCKDPVQEAWAEDVDLRVNLAMNVGKARGFFKKGDV 508
Query: 1565 VVAL 1576
V+ L
Sbjct: 509 VIVL 512
>sp|P30615|KPYK1_TRYBB Pyruvate kinase 1 OS=Trypanosoma brucei brucei GN=PYK1
PE=3 SV=1
Length = 499
Score = 382 bits (981), Expect = 4e-105
Identities = 196/403 (48%), Positives = 276/403 (68%), Gaps = 5/403 (1%)
Frame = +2
Query: 158 KIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMLNTGILCAVM 337
+IVCT+GP+++SVE ++ L+++GM+VAR NFSHGSHEYHQ T++N+R A G+ +
Sbjct: 23 RIVCTIGPSTQSVEALKNLMKSGMSVARMNFSHGSHEYHQTTINNVRAAAAELGLHIGIA 82
Query: 338 LDTKGPEIRTGFLKDGKPIQLTQGQEITVSTD--YDLQGDEETICMSYKKLAEDVNPGMV 511
LDTKGPEIRTG KDG+ + G + V+TD Y+ G +E + Y +L V PG
Sbjct: 83 LDTKGPEIRTGLFKDGE-VSFAPGDIVCVTTDPAYEKVGTKEKFYIDYPQLTNAVRPGGS 141
Query: 512 ILCADGTISLLVLSCDTENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKEDIMK 691
I DG ++L V+S + ++ T++C N L +R+ +NLPG VDLP ++EKD++D ++
Sbjct: 142 IYVDDGVMTLRVVSKE-DDRTLKCHVNNHHRLTDRRGINLPGCEVDLPAVSEKDRKD-LE 199
Query: 692 WGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVANFDDILVNSDAF 871
+GV +DMI SF+R + +VR LG+ K+IL++SK+EN +GV N D I+ S+
Sbjct: 200 FGVAQGVDMIFASFIRTAEQVREVRAALGEKGKDILIISKIENHQGVQNIDSIIEASNGI 259
Query: 872 MIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEATGVAN 1051
M+ARGDLG+EIP EK+ +AQ +I KCN+ GKPV+ ATQMLESM +PRPTRAE + VAN
Sbjct: 260 MVARGDLGVEIPAEKVCVAQMCIISKCNVVGKPVICATQMLESMTSNPRPTRAEVSDVAN 319
Query: 1052 AVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIMQYSPVPMSPLE 1231
AVL+G DCVMLSGETA G YP V+ MA+ICVEA+S +F I +PM P E
Sbjct: 320 AVLNGADCVMLSGETAKGKYPNEVVQYMARICVEAQSATHDTVMFNSIKNLQKIPMCPEE 379
Query: 1232 SLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSV 1360
++ SSAV +A +A ++VL+ G +ARL++KYRP PI+ V
Sbjct: 380 AVCSSAVASAFEVQAKAMLVLSNTGRSARLISKYRPNCPIICV 422
>sp|Q29536|KPYR_CANFA Pyruvate kinase isozyme R (Fragment) OS=Canis familiaris
GN=PKLR PE=2 SV=1
Length = 519
Score = 382 bits (979), Expect = 7e-105
Identities = 208/484 (42%), Positives = 301/484 (62%), Gaps = 26/484 (5%)
Frame = +2
Query: 155 TKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMLNTGIL--- 325
T I+ T+GPAS SVE ++++++AGMN+AR NFSHGSHEYH +++ N+R+A+ +
Sbjct: 33 TSIIATIGPASHSVERLKEMIKAGMNIARLNFSHGSHEYHAQSIANIREAVESFATSPLG 92
Query: 326 ---CAVMLDTKGPEIRTGFLKDG--KPIQLTQGQEITVSTD--YDLQGDEETICMSYKKL 484
A+ LDTKGPEIRTG LK G ++L +G + V+ D + GD T+ + Y +
Sbjct: 93 YRPVAIALDTKGPEIRTGVLKGGPETEVELVKGSWVLVTVDPAFRTLGDAHTVWVDYPNI 152
Query: 485 AEDVNPGMVILCADGTISLLVLSCDTENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLT 664
+ V G I DG ISL V D + + + EN +LG RK VNLPG VDLP L+
Sbjct: 153 VKVVPVGGRIFIDDGLISLQVKKIDRKG--LETQVENGGLLGSRKGVNLPGAEVDLPGLS 210
Query: 665 EKDKEDIMKWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVANFD 844
E+D +D +++GV + +D++ SFVRK SD+ +R LG + I ++SK+EN EGV FD
Sbjct: 211 EQDAQD-LRFGVEHNVDIVFASFVRKASDVAAIRAALGPEGRTIKIISKIENHEGVKKFD 269
Query: 845 DILVNSDAFMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPT 1024
+IL SD M+ARGDLG+EIP EK+FLAQK+MI +CN+ GKPVV ATQMLESMI PRPT
Sbjct: 270 EILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPT 329
Query: 1025 RAEATGVANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIMQY 1204
RAE + VANAVLDG DC+MLSGETA G +P AV+ +I EAE+ + + +F+ + +
Sbjct: 330 RAETSDVANAVLDGADCIMLSGETAKGKFPVEAVKMQHRIAREAEAAVYHRQLFEELRRA 389
Query: 1205 SPVPMSPLESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSVVVPEMKTD 1384
+P+ P E A + V A A I+VLT+ G +A+L+++YRP +++V
Sbjct: 390 APLSRDPTEVTAIATVEAAFKCCAAAIIVLTKTGRSAQLLSRYRPRAAVIAVT------- 442
Query: 1385 FFDWSCSDESPARHSLIFRGLIPVLYAGSARASHDESTEEAIEFATQHGKEKRLCKTGDS 1564
AR + + RG+ P+LY+ A + + ++F + GK + + GD
Sbjct: 443 ------RSAQAARQAHLCRGVFPLLYSEPPEAIWADDVDRRVQFGIESGKLRGFLRVGDL 496
Query: 1565 VVAL 1576
V+ +
Sbjct: 497 VIVV 500
>sp|P30616|KPYK2_TRYBB Pyruvate kinase 2 OS=Trypanosoma brucei brucei GN=PYK2
PE=3 SV=1
Length = 499
Score = 379 bits (973), Expect = 4e-104
Identities = 196/403 (48%), Positives = 276/403 (68%), Gaps = 5/403 (1%)
Frame = +2
Query: 158 KIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMLNTGILCAVM 337
+IVCT+GP+++SVE ++ L+++GM+VAR NFSHGSHEYHQ T++N+R A G+ +
Sbjct: 23 RIVCTIGPSTQSVEALKNLMKSGMSVARMNFSHGSHEYHQTTINNVRAAAAELGLHIGIA 82
Query: 338 LDTKGPEIRTGFLKDGKPIQLTQGQEITVSTD--YDLQGDEETICMSYKKLAEDVNPGMV 511
LDTKGPEIRTG KDG+ + G + V+TD Y+ G +E + Y +L + V G
Sbjct: 83 LDTKGPEIRTGLFKDGE-VTFAPGDIVCVTTDPAYEKVGTKEKFYIDYPQLTKAVPVGGS 141
Query: 512 ILCADGTISLLVLSCDTENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKEDIMK 691
I DG ++L VLS + ++ T++C N L +R+ +NLPG VDLP ++EKD++D ++
Sbjct: 142 IYVDDGVMTLRVLSKE-DDRTLKCHVNNHHRLTDRRGINLPGCEVDLPAVSEKDRKD-LE 199
Query: 692 WGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVANFDDILVNSDAF 871
+GV +DMI SF+R + +VR LG+ K+IL++SK+EN +GV N D I+ S+
Sbjct: 200 FGVAQGVDMIFASFIRTAEQVREVRAALGEKGKDILIISKIENHQGVQNIDSIIEASNGI 259
Query: 872 MIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEATGVAN 1051
M+ARGDLG+EIP EK+ +AQ +I KCN+ GKPV+ ATQMLESM +PRPTRAE + VAN
Sbjct: 260 MVARGDLGVEIPAEKVCVAQMCIISKCNVVGKPVICATQMLESMTSNPRPTRAEVSDVAN 319
Query: 1052 AVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIMQYSPVPMSPLE 1231
AVL+G DCVMLSGETA G YP V+ MA+ICVEA+S +F I +PM P E
Sbjct: 320 AVLNGADCVMLSGETAKGKYPNEVVQYMARICVEAQSATHDTVMFNSIKNLQKIPMCPEE 379
Query: 1232 SLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSV 1360
++ SSAV +A +A ++VL+ G +ARL++KYRP PI+ V
Sbjct: 380 AVCSSAVASAFEVQAKAMLVLSNTGRSARLISKYRPNCPIICV 422
>sp|O94122|KPYK_AGABI Pyruvate kinase OS=Agaricus bisporus GN=pkiA PE=2 SV=1
Length = 532
Score = 377 bits (968), Expect = 1e-103
Identities = 201/407 (49%), Positives = 271/407 (66%), Gaps = 7/407 (1%)
Frame = +2
Query: 152 KTKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQAMLNT--GIL 325
KT I+ T+GP +VE + + AG+N+ R NFSHG+HEYHQ +DN RQ + N G
Sbjct: 34 KTAIIATIGPKINTVEKLTDVRLAGVNIVRMNFSHGTHEYHQSVIDNTRQMIKNDPHGRP 93
Query: 326 CAVMLDTKGPEIRTGFLKDGKPIQLTQGQEITVSTD--YDLQGDEETICMSYKKLAEDVN 499
A+ LDTKGPEIRTG +DG + G E V+TD Y D + + + Y LA
Sbjct: 94 VAIALDTKGPEIRTGQTRDGNDYPIKAGDEFIVTTDPKYSDICDNKVLFVDYANLASVTA 153
Query: 500 PGMVILCADGTISLLVLSCDTENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKE 679
PG +I DG ISLL+LS D N + R N+ L RK VNLP VDLP L+EKDK+
Sbjct: 154 PGKLIYIDDGIISLLILSIDGMN--LHVRALNNGTLSSRKGVNLPKTDVDLPPLSEKDKD 211
Query: 680 DIMKWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVANFDDILVN 859
D +++G+ N +DMI SF+R+G D+ Q+R++LG +I ++ K+EN++GVANFD+IL
Sbjct: 212 D-LRFGIRNGVDMIFASFIRRGEDVRQIREVLGPDGASIKIIVKIENEQGVANFDEILKE 270
Query: 860 SDAFMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEAT 1039
+D M+ARGDLG+EIP ++FLAQK+MI KCNI GKPV+ ATQMLESM +PRPTRAE +
Sbjct: 271 ADGVMVARGDLGIEIPASQVFLAQKMMIAKCNIVGKPVIVATQMLESMTYNPRPTRAEVS 330
Query: 1040 GVANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIMQYSPVPM 1219
VANAVLDG+DCVMLSGETA G+YP +V MA+ C+ AE+ + Y ++ + P
Sbjct: 331 DVANAVLDGSDCVMLSGETAKGSYPVQSVLMMAETCLLAETAICYPPLYDDLRAVQARPT 390
Query: 1220 SPLESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSV 1360
E++A +AV A A ++VL+ G TARLV+KYRP +PI++V
Sbjct: 391 ETAETVAIAAVAAAAEQDAKALLVLSTSGETARLVSKYRPKIPIITV 437
>sp|Q7RVA8|KPYK_NEUCR Pyruvate kinase OS=Neurospora crassa GN=pyk-1 PE=3 SV=1
Length = 527
Score = 372 bits (955), Expect = 4e-102
Identities = 190/406 (46%), Positives = 276/406 (67%), Gaps = 5/406 (1%)
Frame = +2
Query: 152 KTKIVCTLGPASRSVEMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLRQA-MLNTGILC 328
+T I+CT+GP + SVE + KL AG+NV R NFSHGS+EYHQ +DN RQA ++ G
Sbjct: 33 RTSIICTIGPKTNSVEAINKLRDAGLNVVRMNFSHGSYEYHQSVIDNARQAEKVHPGRPI 92
Query: 329 AVMLDTKGPEIRTGFLKDGKPIQLTQGQEITVSTD--YDLQGDEETICMSYKKLAEDVNP 502
A+ LDTKGPEIRTG K+ + I ++ G + ++TD Y + E + + Y + + + P
Sbjct: 93 AIALDTKGPEIRTGNTKNDEDIPISAGTILNITTDEKYKDECTIEHMYVDYVNITKVIAP 152
Query: 503 GMVILCADGTISLLVLSCDTENGTVRCRCENSAMLGERKNVNLPGVVVDLPTLTEKDKED 682
G +I DG ++ VL ++ T++ + N+ + RK VNLP VDLP L+EKDK D
Sbjct: 153 GRIIYVDDGVLAFEVLEI-VDDKTIKVKARNNGYISSRKGVNLPNTDVDLPALSEKDKAD 211
Query: 683 IMKWGVPNQIDMIALSFVRKGSDLVQVRKLLGDHAKNILLMSKVENQEGVANFDDILVNS 862
+++GV N++DM+ SF+R+G D+ +R++LG+ K I +++K+EN++G+ NF +IL +
Sbjct: 212 -LRFGVKNKVDMVFASFIRRGQDIKDIREVLGEDGKQIQIIAKIENRQGLNNFAEILAET 270
Query: 863 DAFMIARGDLGMEIPIEKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEATG 1042
D M+ARGDLG+EIP ++F AQK +I CNI GKPV+ ATQMLESMIK+PRPTRAE +
Sbjct: 271 DGVMVARGDLGIEIPAAEVFAAQKKIIAMCNIAGKPVICATQMLESMIKNPRPTRAEISD 330
Query: 1043 VANAVLDGTDCVMLSGETAAGAYPELAVRTMAKICVEAESTLDYGDVFKGIMQYSPVPMS 1222
V NAV DG DCVMLSGETA GAYP AVR M++ ++AE+T+ Y F+ + + P+S
Sbjct: 331 VGNAVTDGADCVMLSGETAKGAYPTEAVREMSEAVLKAENTIPYVSHFEELCSLAKRPVS 390
Query: 1223 PLESLASSAVRTANSARATLIMVLTRGGSTARLVAKYRPGMPILSV 1360
+ES A ++VR + A I+VL+ G +ARL++KYRP PI+ +
Sbjct: 391 IVESCAMASVRASLDLNAAAILVLSTSGESARLISKYRPVCPIIMI 436
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 116,323,427,680
Number of Sequences: 518415
Number of Extensions: 116323427680
Number of Successful Extensions: 743337835
Number of sequences better than 0.0: 0
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