BLASTX 7.6.2
Query= UN28904 /QuerySize=1405
(1404 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q5BIP7|LIAS_BOVIN Lipoyl synthase, mitochondrial OS=Bos tauru... 387 1e-106
sp|O43766|LIAS_HUMAN Lipoyl synthase, mitochondrial OS=Homo sapi... 387 2e-106
sp|Q5XIH4|LIAS_RAT Lipoyl synthase, mitochondrial OS=Rattus norv... 386 3e-106
sp|Q99M04|LIAS_MOUSE Lipoyl synthase, mitochondrial OS=Mus muscu... 382 5e-105
sp|O13642|LIPA_SCHPO Lipoyl synthase, mitochondrial OS=Schizosac... 360 2e-098
sp|P32875|LIP5_YEAST Lipoyl synthase, mitochondrial OS=Saccharom... 350 2e-095
sp|Q3IU11|LIPA_NATPD Probable lipoyl synthase OS=Natronomonas ph... 314 1e-084
sp|A1U380|LIPA_MARAV Lipoyl synthase OS=Marinobacter aquaeolei (... 311 1e-083
sp|Q72GV1|LIPA_THET2 Lipoyl synthase OS=Thermus thermophilus (st... 305 5e-082
sp|Q5SLQ4|LIPA_THET8 Lipoyl synthase OS=Thermus thermophilus (st... 305 5e-082
sp|Q9RWA4|LIPA_DEIRA Lipoyl synthase OS=Deinococcus radiodurans ... 292 7e-078
sp|A1WT98|LIPA_HALHL Lipoyl synthase OS=Halorhodospira halophila... 289 3e-077
sp|Q1IXJ7|LIPA_DEIGD Lipoyl synthase OS=Deinococcus geothermalis... 288 8e-077
sp|A7NBV0|LIPA_FRATF Lipoyl synthase OS=Francisella tularensis s... 287 2e-076
sp|Q2A3R2|LIPA_FRATH Lipoyl synthase OS=Francisella tularensis s... 287 2e-076
sp|Q0BM68|LIPA_FRATO Lipoyl synthase OS=Francisella tularensis s... 287 2e-076
sp|Q14IH3|LIPA_FRAT1 Lipoyl synthase OS=Francisella tularensis s... 285 7e-076
sp|A0Q6Q2|LIPA_FRATN Lipoyl synthase OS=Francisella tularensis s... 285 7e-076
sp|Q5NH21|LIPA_FRATT Lipoyl synthase OS=Francisella tularensis s... 285 7e-076
sp|A4IY90|LIPA_FRATW Lipoyl synthase OS=Francisella tularensis s... 285 7e-076
>sp|Q5BIP7|LIAS_BOVIN Lipoyl synthase, mitochondrial OS=Bos taurus GN=LIAS PE=2
SV=1
Length = 372
Score = 387 bits (993), Expect = 1e-106
Identities = 192/343 (55%), Positives = 247/343 (72%), Gaps = 2/343 (0%)
Frame = +3
Query: 114 SPITPVSSATTQSPRTLESLRARLADESPSLTDFIHGDTYSVEVGTKK-KPLPKPKWMKE 290
SP+ VS + L+S S +L D D Y + +K + L P W+K
Sbjct: 23 SPVREVSFLPDEKKEFLQSGPDLQEFISGNLADKSTWDEYKGNLKRQKGERLRLPPWLKT 82
Query: 291 SIPGGERYVQIIKKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILGDTCTRGCR 470
IP G+ Y ++ LR+LNLHTVCEEA+CPN+GECW GGE TATATIM++GDTCTRGCR
Sbjct: 83 EIPMGKNYNKLKNTLRNLNLHTVCEEARCPNIGECWGGGEYATATATIMLMGDTCTRGCR 142
Query: 471 FCNVKTSRTPPPPDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAQTVQRLKT 650
FC+VKT+R PPP D NEP N A+AIA WG+DYVV+TSVDRDD+PD G+ HFA+TV LK
Sbjct: 143 FCSVKTARNPPPLDANEPYNTAKAIAEWGLDYVVLTSVDRDDMPDGGAEHFAKTVSYLKE 202
Query: 651 LKPEMLIEALVPDFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRANFKQSMDVL 830
P++L+E L PDFRGD +EKVA SGLDV+AHN+ETV ELQ VRD RANF QS+ VL
Sbjct: 203 RNPKILVECLTPDFRGDLKAIEKVALSGLDVYAHNVETVPELQRKVRDPRANFDQSLRVL 262
Query: 831 RMAKQHAPAGTLTKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSKRHMPVAE 1010
+ AK+ P ++KTS+MLG GE +QV TM+ +R A VD +T GQYM+P+KRH+ V E
Sbjct: 263 KHAKEVRP-DVISKTSIMLGLGENDEQVYATMKALREADVDCLTLGQYMQPTKRHLKVEE 321
Query: 1011 YVTPEAFERYRLLGMEMGFRYVASGPMVRSSYKAGEYYIKSMI 1139
Y+TPE F+ + +G E+GF Y ASGP+VRSSYKAGE+++K+++
Sbjct: 322 YITPEKFKYWEKVGNELGFHYTASGPLVRSSYKAGEFFLKNLV 364
>sp|O43766|LIAS_HUMAN Lipoyl synthase, mitochondrial OS=Homo sapiens GN=LIAS
PE=2 SV=3
Length = 372
Score = 387 bits (992), Expect = 2e-106
Identities = 196/361 (54%), Positives = 256/361 (70%), Gaps = 7/361 (1%)
Frame = +3
Query: 66 ASRFLRPA--SRFFSTSSSPITPVSSATTQSPRTLESLRARLADESPSLTDFIHGDTYSV 239
A+R L P R+F SP+ P+SS + L++ S L D D Y
Sbjct: 8 AARTLGPRVFGRYF---CSPVRPLSSLPDKKKELLQNGPDLQDFVSGDLADRSTWDEYKG 64
Query: 240 EVGTKK-KPLPKPKWMKESIPGGERYVQIIKKLRDLNLHTVCEEAKCPNLGECWSGGETG 416
+ +K + L P W+K IP G+ Y ++ LR+LNLHTVCEEA+CPN+GECW GGE
Sbjct: 65 NLKRQKGERLRLPPWLKTEIPMGKNYNKLKNTLRNLNLHTVCEEARCPNIGECWGGGEYA 124
Query: 417 TATATIMILGDTCTRGCRFCNVKTSRTPPPPDPNEPNNVAEAIASWGVDYVVITSVDRDD 596
TATATIM++GDTCTRGCRFC+VKT+R PPP D +EP N A+AIA WG+DYVV+TSVDRDD
Sbjct: 125 TATATIMLMGDTCTRGCRFCSVKTARNPPPLDASEPYNTAKAIAEWGLDYVVLTSVDRDD 184
Query: 597 LPDQGSGHFAQTVQRLKTLKPEMLIEALVPDFRGDGGCVEKVAKSGLDVFAHNIETVEEL 776
+PD G+ H A+TV LK P++L+E L PDFRGD +EKVA SGLDV+AHN+ETV EL
Sbjct: 185 MPDGGAEHIAKTVSYLKERNPKILVECLTPDFRGDLKAIEKVALSGLDVYAHNVETVPEL 244
Query: 777 QSFVRDHRANFKQSMDVLRMAKQHAPAGTLTKTSVMLGCGETPDQVVKTMEKVRAAGVDV 956
QS VRD RANF QS+ VL+ AK+ P ++KTS+MLG GE +QV TM+ +R A VD
Sbjct: 245 QSKVRDPRANFDQSLRVLKHAKKVQP-DVISKTSIMLGLGENDEQVYATMKALREADVDC 303
Query: 957 MTFGQYMRPSKRHMPVAEYVTPEAFERYRLLGMEMGFRYVASGPMVRSSYKAGEYYIKSM 1136
+T GQYM+P++RH+ V EY+TPE F+ + +G E+GF Y ASGP+VRSSYKAGE+++K++
Sbjct: 304 LTLGQYMQPTRRHLKVEEYITPEKFKYWEKVGNELGFHYTASGPLVRSSYKAGEFFLKNL 363
Query: 1137 I 1139
+
Sbjct: 364 V 364
>sp|Q5XIH4|LIAS_RAT Lipoyl synthase, mitochondrial OS=Rattus norvegicus GN=Lias
PE=2 SV=1
Length = 373
Score = 386 bits (990), Expect = 3e-106
Identities = 194/351 (55%), Positives = 250/351 (71%), Gaps = 2/351 (0%)
Frame = +3
Query: 90 SRFFSTSSSPITPVSSATTQSPRTLESLRARLADESPSLTDFIHGDTYSVEVGTKK-KPL 266
SR F + + +SS + + L + S L D D Y + +K + L
Sbjct: 14 SRIFGRYACSVRALSSLPDEKKKFLHNGPDLQDFVSGDLADKSTWDDYKGNLKRQKGERL 73
Query: 267 PKPKWMKESIPGGERYVQIIKKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILG 446
P W+K IP G+ Y ++ LR+LNLHTVCEEA+CPN+GECW GGE TATATIM++G
Sbjct: 74 RLPPWLKTKIPMGKNYNKLKNTLRNLNLHTVCEEARCPNIGECWGGGEYATATATIMLMG 133
Query: 447 DTCTRGCRFCNVKTSRTPPPPDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFA 626
DTCTRGCRFC+VKT+R PPP DP+EP+N A AIA WG+DYVV+TSVDRDD+ D G+ H A
Sbjct: 134 DTCTRGCRFCSVKTARNPPPLDPSEPDNTARAIAEWGLDYVVLTSVDRDDVVDGGAEHIA 193
Query: 627 QTVQRLKTLKPEMLIEALVPDFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRAN 806
+TV LK P++L+E L PDFRGD VEKVA SGLDV+AHN+ETV ELQ VRD RAN
Sbjct: 194 KTVSCLKERNPKILVECLTPDFRGDLRAVEKVALSGLDVYAHNVETVPELQRKVRDPRAN 253
Query: 807 FKQSMDVLRMAKQHAPAGTLTKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPS 986
F QS+ VL+ AK+ P ++KTS+MLG GET +QV TM+ +RAA VD +T GQYM+P+
Sbjct: 254 FDQSLRVLKHAKEVQP-DVVSKTSIMLGLGETDEQVYATMKALRAADVDCLTLGQYMQPT 312
Query: 987 KRHMPVAEYVTPEAFERYRLLGMEMGFRYVASGPMVRSSYKAGEYYIKSMI 1139
KRH+ V EYVTPE F+ + +G E+GF Y ASGP+VRSSYKAGE+++K+++
Sbjct: 313 KRHLKVEEYVTPEKFKYWEEVGNELGFHYTASGPLVRSSYKAGEFFLKNLV 363
>sp|Q99M04|LIAS_MOUSE Lipoyl synthase, mitochondrial OS=Mus musculus GN=Lias
PE=2 SV=1
Length = 373
Score = 382 bits (979), Expect = 5e-105
Identities = 193/351 (54%), Positives = 249/351 (70%), Gaps = 2/351 (0%)
Frame = +3
Query: 90 SRFFSTSSSPITPVSSATTQSPRTLESLRARLADESPSLTDFIHGDTYSVEVGTKK-KPL 266
SR F + + +SS + L + S L D D Y + +K + L
Sbjct: 14 SRIFGRYAFTVRALSSLPDKKKEFLHNGPDLQDFVSGDLADKSTWDEYKGNLKRQKGERL 73
Query: 267 PKPKWMKESIPGGERYVQIIKKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILG 446
P W+K IP G+ Y ++ LR+L+LHTVCEEA+CPN+GECW GGE TATATIM++G
Sbjct: 74 RLPPWLKTKIPMGKNYNKLKNTLRNLSLHTVCEEARCPNIGECWGGGEYATATATIMLMG 133
Query: 447 DTCTRGCRFCNVKTSRTPPPPDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFA 626
DTCTRGCRFC+VKT+R PPP D NEP+N A+AIA WG+DYVV+TSVDRDD+ D G+ H A
Sbjct: 134 DTCTRGCRFCSVKTARNPPPLDANEPDNTAKAIAEWGLDYVVLTSVDRDDVADGGAEHIA 193
Query: 627 QTVQRLKTLKPEMLIEALVPDFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRAN 806
+TV LK P++L+E L PDFRGD VEKVA SGLDV+AHN+ETV ELQ VRD RAN
Sbjct: 194 KTVSCLKERNPKILVECLTPDFRGDLRAVEKVALSGLDVYAHNVETVPELQRKVRDPRAN 253
Query: 807 FKQSMDVLRMAKQHAPAGTLTKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPS 986
F QS+ VLR AK+ P ++KTS+MLG GET +QV T++ +RAA VD +T GQYM+P+
Sbjct: 254 FDQSLRVLRHAKEVQP-DVVSKTSIMLGLGETDEQVYATLKALRAADVDCLTLGQYMQPT 312
Query: 987 KRHMPVAEYVTPEAFERYRLLGMEMGFRYVASGPMVRSSYKAGEYYIKSMI 1139
KRH+ V EYVTPE F+ + +G E+GF Y ASGP+VRSSYKAGE+++K+++
Sbjct: 313 KRHLKVEEYVTPEKFKYWEKVGNELGFLYTASGPLVRSSYKAGEFFLKNLV 363
>sp|O13642|LIPA_SCHPO Lipoyl synthase, mitochondrial OS=Schizosaccharomyces
pombe GN=SPBC8D2.15 PE=2 SV=2
Length = 370
Score = 360 bits (923), Expect = 2e-098
Identities = 172/299 (57%), Positives = 224/299 (74%), Gaps = 2/299 (0%)
Frame = +3
Query: 273 PKWMKESIPGGERYVQIIKKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILGDT 452
P W+K +P G + +I LR +LHTVCEEAKCPN+GECW G + ATATIM++GDT
Sbjct: 71 PSWLKTKVPLGTNFNRIKHDLRGSHLHTVCEEAKCPNIGECWGGKDKSRATATIMLMGDT 130
Query: 453 CTRGCRFCNVKTSRTPPPPDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAQT 632
CTRGCRFC+VKTSR P P DPNEP N AEAI W + Y+V+TSVDRDDL D G+ H A+T
Sbjct: 131 CTRGCRFCSVKTSRRPGPLDPNEPENTAEAIKQWNLGYIVLTSVDRDDLTDLGANHIAKT 190
Query: 633 VQRLKTLKPEMLIEALVPDFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRANFK 812
+Q++K P +L+EAL PDF G VE VAKSGLDVFAHN+ETVEEL FVRD RA ++
Sbjct: 191 IQKIKEKAPHILVEALTPDFSGRMDLVEIVAKSGLDVFAHNVETVEELTPFVRDRRATYR 250
Query: 813 QSMDVLRMAKQHAPAGTLTKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSKR 992
QS+ VL+ K+ P +TKTS+MLG GET +++ T++ + VDV+TFGQYMRP+KR
Sbjct: 251 QSLSVLKHVKKTCP-HLITKTSIMLGLGETDAEILTTLKDLLEHNVDVVTFGQYMRPTKR 309
Query: 993 HMPVAEYVTPEAFERYRLLGMEMGFRYVASGPMVRSSYKAGEYYIKSMIEADRVSSPSS 1169
H+ V EYV P+ FE ++ + ++GF YVASGP+VRSSYKAGEY+++++I+ R +P+S
Sbjct: 310 HLKVQEYVHPKKFEYWKEVAEKLGFLYVASGPLVRSSYKAGEYFMENLIK-KRSGNPAS 367
>sp|P32875|LIP5_YEAST Lipoyl synthase, mitochondrial OS=Saccharomyces cerevisiae
GN=LIP5 PE=1 SV=1
Length = 414
Score = 350 bits (897), Expect = 2e-095
Identities = 170/322 (52%), Positives = 226/322 (70%), Gaps = 8/322 (2%)
Frame = +3
Query: 198 PSLTDFIHGDTYSVEVGTKKKPLPK-------PKWMKESIPGGERYVQIIKKLRDLNLHT 356
PS DF+ G + + +K P+W+K IP G Y ++ +++L L T
Sbjct: 89 PSFADFVSGKASKMILDPLEKARQNTEEAKKLPRWLKVPIPKGTNYHKLKGDVKELGLST 148
Query: 357 VCEEAKCPNLGECWSGGETGTATATIMILGDTCTRGCRFCNVKTSRTPPPPDPNEPNNVA 536
VCEEA+CPN+GECW G + ATATIM+LGDTCTRGCRFC+VKT+RTP PDP EP N A
Sbjct: 149 VCEEARCPNIGECWGGKDKSKATATIMLLGDTCTRGCRFCSVKTNRTPSKPDPMEPENTA 208
Query: 537 EAIASWGVDYVVITSVDRDDLPDQGSGHFAQTVQRLKTLKPEMLIEALVPDFRGDGGCVE 716
EAI WG+ YVV+T+VDRDDL D G+ H A+TV+++K P L+E L DFRGD V+
Sbjct: 209 EAIKRWGLGYVVLTTVDRDDLVDGGANHLAETVRKIKQKAPNTLVETLSGDFRGDLKMVD 268
Query: 717 KVAKSGLDVFAHNIETVEELQSFVRDHRANFKQSMDVLRMAKQHAPAGTLTKTSVMLGCG 896
+A+ GLDV+AHN+ETVE L VRD RA ++QS+ VL AK P+ +TKTS+MLG G
Sbjct: 269 IMAQCGLDVYAHNLETVESLTPHVRDRRATYRQSLSVLERAKATVPS-LITKTSIMLGLG 327
Query: 897 ETPDQVVKTMEKVRAAGVDVMTFGQYMRPSKRHMPVAEYVTPEAFERYRLLGMEMGFRYV 1076
ET +Q+ +T++ +R DV+TFGQYMRP+KRHM V EYV PE F+ ++ +EMGF Y
Sbjct: 328 ETDEQITQTLKDLRNIQCDVVTFGQYMRPTKRHMKVVEYVKPEKFDYWKERALEMGFLYC 387
Query: 1077 ASGPMVRSSYKAGEYYIKSMIE 1142
ASGP+VRSSYKAGE +I+++++
Sbjct: 388 ASGPLVRSSYKAGEAFIENVLK 409
>sp|Q3IU11|LIPA_NATPD Probable lipoyl synthase OS=Natronomonas pharaonis (strain
DSM 2160 / ATCC 35678) GN=lipA PE=3 SV=1
Length = 309
Score = 314 bits (804), Expect = 1e-084
Identities = 158/304 (51%), Positives = 215/304 (70%), Gaps = 11/304 (3%)
Frame = +3
Query: 270 KPKWMKESIPGGERYVQIIKKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILGD 449
KP+W++ P G R+ +I + LRD +L+TVCEEA CPNLG+CWSG + G TAT M+LGD
Sbjct: 7 KPEWLRTRPPSGRRFTEIKETLRDRDLNTVCEEANCPNLGDCWSGRD-GPGTATFMLLGD 65
Query: 450 TCTRGCRFCNVKTSRTPPPPDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAQ 629
C+RGC FC+V T P DP+EP NVAEA+A G+DYVV+TSVDRDDL D G+GHFA+
Sbjct: 66 RCSRGCNFCDVATGGM-DPLDPDEPANVAEAVAEIGLDYVVLTSVDRDDLDDGGAGHFAE 124
Query: 630 TVQRLKTLKPEMLIEALVPDFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRANF 809
T++ +K +L+EAL+PDF+GD V+++ + DV AHN+ETVE LQ VRD RA +
Sbjct: 125 TIREIKRRDTSVLVEALIPDFQGDTDAVDRIIDADPDVVAHNVETVERLQWPVRDRRAGY 184
Query: 810 KQSMDVLRMAKQHAPAGTLTKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSK 989
+QS+DVLR A G KTS+MLG GE +V +T+ + GVD++TFGQY++PS+
Sbjct: 185 EQSLDVLRQIA--AADGCYAKTSLMLGVGEYAHEVYRTLGDLSEVGVDIVTFGQYLQPSR 242
Query: 990 RHMPVAEYVTPEAFERY-RLLGMEMGFRYVASGPMVRSSYKAGEYYIKSM------IEAD 1148
H+ V EYVTP+ F+ + R+ E GF Y ASGPMVRSS+KAGE +++++ IEA
Sbjct: 243 SHLEVFEYVTPDTFDVWKRVAETEFGFLYCASGPMVRSSFKAGELFVEALERDGLDIEAA 302
Query: 1149 RVSS 1160
R ++
Sbjct: 303 RAAA 306
>sp|A1U380|LIPA_MARAV Lipoyl synthase OS=Marinobacter aquaeolei (strain ATCC
700491 / DSM 11845 / VT8) GN=lipA PE=3 SV=1
Length = 348
Score = 311 bits (795), Expect = 1e-083
Identities = 149/288 (51%), Positives = 200/288 (69%), Gaps = 6/288 (2%)
Frame = +3
Query: 270 KPKWMKESIPGGERYVQIIKKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILGD 449
KPKW++ +PGGERY + + + + L TVC+E+ CPN+GECW+ G TATIM++G
Sbjct: 43 KPKWLRARMPGGERYDAVRRNVTEHRLSTVCQESHCPNIGECWTNG-----TATIMVMGS 97
Query: 450 TCTRGCRFCNVKTSRTPPPPDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAQ 629
CTR C+FC V T DP EP N A+++ G+ Y+V+TSVDRDDLPD G+ H+A
Sbjct: 98 VCTRACKFCAVDTGNPKGWLDPEEPENTAKSVELMGLRYIVLTSVDRDDLPDGGAAHYAA 157
Query: 630 TVQRLKTLKPEMLIEALVPDFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRANF 809
V +K PE+ +EAL PDF VEKV SGLDVFA N+ETV+ L S VRD RA +
Sbjct: 158 CVSAIKQRTPEVAVEALTPDFDAVMSDVEKVVDSGLDVFAQNVETVKRLTSRVRDPRAGY 217
Query: 810 KQSMDVLRMAKQHAPAGTLTKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSK 989
++++ VL AK+H P LTKTS+MLG GET +++++TM+ +RA GVD++T GQY+RP+
Sbjct: 218 EKTLSVLAHAKKHRP-DVLTKTSLMLGLGETEEEILETMDDLRAIGVDILTLGQYLRPTP 276
Query: 990 RHMPVAEYVTPEAFERYRLLGMEMGFRYVASGPMVRSSYKAGEYYIKS 1133
H+PV YVTPE F RYR +G+E GF V SGPMVRSSY+A + K+
Sbjct: 277 NHLPVERYVTPEEFNRYRDIGLEKGFMEVPSGPMVRSSYRADRVFDKN 324
>sp|Q72GV1|LIPA_THET2 Lipoyl synthase OS=Thermus thermophilus (strain HB27 /
ATCC BAA-163 / DSM 7039) GN=lipA PE=3 SV=1
Length = 323
Score = 305 bits (781), Expect = 5e-082
Identities = 150/288 (52%), Positives = 199/288 (69%), Gaps = 6/288 (2%)
Frame = +3
Query: 270 KPKWMKESIPGGERYVQIIKKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILGD 449
KP W+K +P G RY + +R+L LHTVC+EA CPN+GECW+ G T T+MILGD
Sbjct: 39 KPAWIKAPLPTGPRYQALKAMVRELRLHTVCQEALCPNIGECWTHG-----TLTVMILGD 93
Query: 450 TCTRGCRFCNVKTSRTPPPPDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAQ 629
CTR C+FC V T DP EP VAEAIA GV YVV+TSVDRDDLPD G+ HFA
Sbjct: 94 ICTRACKFCAVHTGNPKGLVDPEEPRRVAEAIARMGVRYVVLTSVDRDDLPDGGASHFAA 153
Query: 630 TVQRLKTLKPEMLIEALVPDFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRANF 809
T++ +K P +L+EAL PDF+GD VE V + +V+A N+ETV L VRD RA +
Sbjct: 154 TIRAIKERAPGVLVEALTPDFQGDLKAVETVLAANPEVYAQNLETVRRLTPKVRDPRAGY 213
Query: 810 KQSMDVLRMAKQHAPAGTLTKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSK 989
+Q++ VL AK+ P LTK+S+MLG GET +++++ M +RAAGVD++T GQY+RP+
Sbjct: 214 EQTLKVLAHAKKVRP-DILTKSSLMLGLGETEEEILEAMRDLRAAGVDILTLGQYLRPTP 272
Query: 990 RHMPVAEYVTPEAFERYRLLGMEMGFRYVASGPMVRSSYKAGEYYIKS 1133
H+PVA YV PE F+RY G E+GFR V +GP+VRSSY+A ++++
Sbjct: 273 AHLPVARYVPPEDFKRYEAWGYELGFREVFAGPLVRSSYRADRVFLEA 320
>sp|Q5SLQ4|LIPA_THET8 Lipoyl synthase OS=Thermus thermophilus (strain HB8 / ATCC
27634 / DSM 579) GN=lipA PE=3 SV=1
Length = 323
Score = 305 bits (781), Expect = 5e-082
Identities = 150/288 (52%), Positives = 199/288 (69%), Gaps = 6/288 (2%)
Frame = +3
Query: 270 KPKWMKESIPGGERYVQIIKKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILGD 449
KP W+K +P G RY + +R+L LHTVC+EA CPN+GECW+ G T T+MILGD
Sbjct: 39 KPAWIKAPLPTGPRYQALKAMVRELRLHTVCQEALCPNIGECWTHG-----TLTVMILGD 93
Query: 450 TCTRGCRFCNVKTSRTPPPPDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAQ 629
CTR C+FC V T DP EP VAEAIA GV YVV+TSVDRDDLPD G+ HFA
Sbjct: 94 ICTRACKFCAVHTGNPKGLVDPEEPRRVAEAIARMGVRYVVLTSVDRDDLPDGGASHFAA 153
Query: 630 TVQRLKTLKPEMLIEALVPDFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRANF 809
T++ +K P +L+EAL PDF+GD VE V + +V+A N+ETV L VRD RA +
Sbjct: 154 TIRAIKERAPGVLVEALTPDFQGDLKAVETVLAANPEVYAQNLETVRRLTPKVRDPRAGY 213
Query: 810 KQSMDVLRMAKQHAPAGTLTKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSK 989
+Q++ VL AK+ P LTK+S+MLG GET +++++ M +RAAGVD++T GQY+RP+
Sbjct: 214 EQTLKVLAHAKKVRP-DILTKSSLMLGLGETEEEILEAMRDLRAAGVDILTLGQYLRPTP 272
Query: 990 RHMPVAEYVTPEAFERYRLLGMEMGFRYVASGPMVRSSYKAGEYYIKS 1133
H+PVA YV PE F+RY G E+GFR V +GP+VRSSY+A ++++
Sbjct: 273 AHLPVARYVPPEDFKRYEAWGYELGFREVFAGPLVRSSYRADRVFLEA 320
>sp|Q9RWA4|LIPA_DEIRA Lipoyl synthase OS=Deinococcus radiodurans GN=lipA PE=3
SV=1
Length = 331
Score = 292 bits (745), Expect = 7e-078
Identities = 142/281 (50%), Positives = 195/281 (69%), Gaps = 6/281 (2%)
Frame = +3
Query: 270 KPKWMKESIPGGERYVQIIKKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILGD 449
KP+W+K +IP G+ + ++ K +++ LHTVCEEA CPN+GECWS G TAT M++G
Sbjct: 30 KPEWLKVTIPTGQVFTEVRKIVKEHRLHTVCEEAMCPNIGECWSRG-----TATFMLMGH 84
Query: 450 TCTRGCRFCNVKTSRTPPPPDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAQ 629
CTR CRFC V T D +EP +VA+++ + YVV+TSVDRDDLPD G+ HFA+
Sbjct: 85 ICTRACRFCAVDTGNPMGKLDLDEPRSVADSVRLMDLKYVVLTSVDRDDLPDGGAYHFAK 144
Query: 630 TVQRLKTLKPEMLIEALVPDFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRANF 809
TV+ +K + P+ +EAL PDF G+ CV+ V SG+D +A N+ETV L VRD RA++
Sbjct: 145 TVKAIKEVNPQTRVEALTPDFGGNTACVDLVLDSGVDTYAQNLETVRRLTHPVRDIRASY 204
Query: 810 KQSMDVLRMAKQHAPAGTLTKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSK 989
+++ VL AKQ P +TKTS+MLG GET +++ + M RAAGVDV+TFGQY+RP+
Sbjct: 205 DRTLSVLAHAKQARP-DVITKTSLMLGLGETREEIREAMADCRAAGVDVLTFGQYLRPTM 263
Query: 990 RHMPVAEYVTPEAFERYRLLGMEMGFRYVASGPMVRSSYKA 1112
H+PV Y++P F+ R GM++GF V SGP+VRSSYKA
Sbjct: 264 HHLPVERYISPAEFDEIREEGMQLGFLEVVSGPLVRSSYKA 304
>sp|A1WT98|LIPA_HALHL Lipoyl synthase OS=Halorhodospira halophila (strain DSM
244 / SL1) GN=lipA PE=3 SV=1
Length = 334
Score = 289 bits (739), Expect = 3e-077
Identities = 145/299 (48%), Positives = 197/299 (65%), Gaps = 11/299 (3%)
Frame = +3
Query: 270 KPKWMKESIPGGERYVQIIKKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILGD 449
KP+W+K PGGE Y + + D +L TVCEE+ CPNLGECWS G TAT M+LG
Sbjct: 41 KPQWLKARAPGGEGYRSVRGIVHDHHLSTVCEESHCPNLGECWSHG-----TATFMVLGS 95
Query: 450 TCTRGCRFCNVKTSRTPPPPDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAQ 629
CTR CRFC+V T DP EP + AE++ G+ YVV+TSVDRDDLPD G+ H+AQ
Sbjct: 96 VCTRTCRFCSVDTGNPKGRLDPQEPEHCAESVRLMGLRYVVLTSVDRDDLPDGGAEHYAQ 155
Query: 630 TVQRLKTLKPEMLIEALVPDFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRANF 809
V+ +K P+ +EAL PDFRGD V V SGL+VFAHN+E V L VRD RA +
Sbjct: 156 CVRAIKADNPDTAVEALTPDFRGDEEAVRTVVDSGLEVFAHNVEVVRRLSPQVRDPRAGY 215
Query: 810 KQSMDVLRMAKQHAPAGTLTKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSK 989
+QS+ VL++AK+ P G LTK+S+M+G GET ++ + + + A VD++T GQY++P++
Sbjct: 216 EQSLAVLQVAKRLRP-GVLTKSSLMVGLGETDAEIDEAFDDLLRAEVDIVTLGQYLQPTR 274
Query: 990 RHMPVAEYVTPEAFERYRLLGMEMGFRYVASGPMVRSSYKAGEYYIKSMIEADRVSSPS 1166
H+PV +V+P+ FE R G+ GFR V +GP+VRSSY+A ++E + V PS
Sbjct: 275 NHLPVERFVSPDEFEALRQEGLRRGFREVVAGPLVRSSYRADR-----VLEGNNVGLPS 328
>sp|Q1IXJ7|LIPA_DEIGD Lipoyl synthase OS=Deinococcus geothermalis (strain DSM
11300) GN=lipA PE=3 SV=1
Length = 328
Score = 288 bits (736), Expect = 8e-077
Identities = 144/281 (51%), Positives = 194/281 (69%), Gaps = 6/281 (2%)
Frame = +3
Query: 270 KPKWMKESIPGGERYVQIIKKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILGD 449
KP+W+K +IP G+ Y ++ K +++ LHTVCEEA CPN+GECWS G TAT M++G
Sbjct: 27 KPEWLKVTIPTGQVYGEVRKIVKEHRLHTVCEEAMCPNIGECWSRG-----TATFMLMGH 81
Query: 450 TCTRGCRFCNVKTSRTPPPPDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAQ 629
CTR CRFC V T D EP +VAE++ G+ YVV+TSVDRDDLPD G+ HFA+
Sbjct: 82 ICTRACRFCAVDTGNPMGKLDLEEPAHVAESVRLMGLKYVVLTSVDRDDLPDGGAYHFAK 141
Query: 630 TVQRLKTLKPEMLIEALVPDFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRANF 809
TV +K P +EAL PDF G+ CV+ V +SG+DV+A N+ETV L VRD RA++
Sbjct: 142 TVTAIKRENPGTRVEALTPDFGGNPHCVDLVLESGVDVYAQNLETVRRLTHPVRDIRASY 201
Query: 810 KQSMDVLRMAKQHAPAGTLTKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSK 989
++++ VL+ AKQ P +TKTS+MLG GET +++ + M RA GVDV+TFGQY+RP+
Sbjct: 202 ERTLGVLKHAKQSRP-DVITKTSIMLGLGETREELREAMLDCRAHGVDVITFGQYLRPTM 260
Query: 990 RHMPVAEYVTPEAFERYRLLGMEMGFRYVASGPMVRSSYKA 1112
H+PV YV+P F+ R G+ +GF V +GP+VRSSYKA
Sbjct: 261 HHLPVERYVSPAEFDEIREEGLSLGFLEVVAGPLVRSSYKA 301
>sp|A7NBV0|LIPA_FRATF Lipoyl synthase OS=Francisella tularensis subsp.
holarctica (strain FTNF002-00 / FTA) GN=lipA PE=3 SV=1
Length = 327
Score = 287 bits (733), Expect = 2e-076
Identities = 146/332 (43%), Positives = 212/332 (63%), Gaps = 14/332 (4%)
Frame = +3
Query: 162 LESLRARLADESPSLTDFIHGDTYSVEVGTKKKP-----LPKPKWMKESIPGGERYVQII 326
+ ++ ++ S TD HG Y+V+ G + K + KP W+K + Y+++
Sbjct: 4 ISGIKVKVESGSKYTTD--HG-FYAVKDGIRNKKENAVHVRKPDWLKVQKQDSKEYLKVK 60
Query: 327 KKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILGDTCTRGCRFCNVKTSRTPPP 506
+ L TVCEEA+CPN+ ECWS G TATIM++G CTR C+FC+V T
Sbjct: 61 SITKKHKLSTVCEEARCPNINECWSHG-----TATIMLMGSVCTRACKFCSVDTGNPKGW 115
Query: 507 PDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAQTVQRLKTLKPEMLIEALVP 686
D +EP N AE++ G++YVV+TSVDRDDL D G+GH+A T+ +K L + +EAL P
Sbjct: 116 LDKDEPMNAAESVKLMGLEYVVLTSVDRDDLEDGGAGHYAATITAIKNLDENIKVEALTP 175
Query: 687 DFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRANFKQSMDVLRMAKQHAPAGTL 866
DF G ++K+ + +DV A NIETVE L VRD RA + Q+++ L+ KQ +P L
Sbjct: 176 DFAGINENIDKIINTKVDVIAQNIETVERLTHPVRDPRAGYWQTLNFLKYVKQKSP-NVL 234
Query: 867 TKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSKRHMPVAEYVTPEAFERYRL 1046
TKTS+M+G GET +++ KTM+ R+ GVD++T GQYM+P+K H+ V +VTP+ FE YR
Sbjct: 235 TKTSIMVGLGETDEEIYKTMDDARSVGVDIITLGQYMQPTKHHLSVERFVTPQQFEEYRK 294
Query: 1047 LGMEMGFRYVASGPMVRSSYKAGEYYIKSMIE 1142
+G+E GF VASGPMVRSSY+A + ++ ++
Sbjct: 295 VGLEKGFLEVASGPMVRSSYRADRVFKRNNLD 326
>sp|Q2A3R2|LIPA_FRATH Lipoyl synthase OS=Francisella tularensis subsp.
holarctica (strain LVS) GN=lipA PE=3 SV=1
Length = 327
Score = 287 bits (733), Expect = 2e-076
Identities = 146/332 (43%), Positives = 212/332 (63%), Gaps = 14/332 (4%)
Frame = +3
Query: 162 LESLRARLADESPSLTDFIHGDTYSVEVGTKKKP-----LPKPKWMKESIPGGERYVQII 326
+ ++ ++ S TD HG Y+V+ G + K + KP W+K + Y+++
Sbjct: 4 ISGIKVKVESGSKYTTD--HG-FYAVKDGIRNKKENAVHVRKPDWLKVQKQDSKEYLKVK 60
Query: 327 KKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILGDTCTRGCRFCNVKTSRTPPP 506
+ L TVCEEA+CPN+ ECWS G TATIM++G CTR C+FC+V T
Sbjct: 61 SITKKHKLSTVCEEARCPNINECWSHG-----TATIMLMGSVCTRACKFCSVDTGNPKGW 115
Query: 507 PDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAQTVQRLKTLKPEMLIEALVP 686
D +EP N AE++ G++YVV+TSVDRDDL D G+GH+A T+ +K L + +EAL P
Sbjct: 116 LDKDEPMNAAESVKLMGLEYVVLTSVDRDDLEDGGAGHYAATITAIKNLDENIKVEALTP 175
Query: 687 DFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRANFKQSMDVLRMAKQHAPAGTL 866
DF G ++K+ + +DV A NIETVE L VRD RA + Q+++ L+ KQ +P L
Sbjct: 176 DFAGINENIDKIINTKVDVIAQNIETVERLTHPVRDPRAGYWQTLNFLKYVKQKSP-NVL 234
Query: 867 TKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSKRHMPVAEYVTPEAFERYRL 1046
TKTS+M+G GET +++ KTM+ R+ GVD++T GQYM+P+K H+ V +VTP+ FE YR
Sbjct: 235 TKTSIMVGLGETDEEIYKTMDDARSVGVDIITLGQYMQPTKHHLSVERFVTPQQFEEYRK 294
Query: 1047 LGMEMGFRYVASGPMVRSSYKAGEYYIKSMIE 1142
+G+E GF VASGPMVRSSY+A + ++ ++
Sbjct: 295 VGLEKGFLEVASGPMVRSSYRADRVFKRNNLD 326
>sp|Q0BM68|LIPA_FRATO Lipoyl synthase OS=Francisella tularensis subsp.
holarctica (strain OSU18) GN=lipA PE=3 SV=1
Length = 327
Score = 287 bits (733), Expect = 2e-076
Identities = 146/332 (43%), Positives = 212/332 (63%), Gaps = 14/332 (4%)
Frame = +3
Query: 162 LESLRARLADESPSLTDFIHGDTYSVEVGTKKKP-----LPKPKWMKESIPGGERYVQII 326
+ ++ ++ S TD HG Y+V+ G + K + KP W+K + Y+++
Sbjct: 4 ISGIKVKVESGSKYTTD--HG-FYAVKDGIRNKKENAVHVRKPDWLKVQKQDSKEYLKVK 60
Query: 327 KKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILGDTCTRGCRFCNVKTSRTPPP 506
+ L TVCEEA+CPN+ ECWS G TATIM++G CTR C+FC+V T
Sbjct: 61 SITKKHKLSTVCEEARCPNINECWSHG-----TATIMLMGSVCTRACKFCSVDTGNPKGW 115
Query: 507 PDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAQTVQRLKTLKPEMLIEALVP 686
D +EP N AE++ G++YVV+TSVDRDDL D G+GH+A T+ +K L + +EAL P
Sbjct: 116 LDKDEPMNAAESVKLMGLEYVVLTSVDRDDLEDGGAGHYAATITAIKNLDENIKVEALTP 175
Query: 687 DFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRANFKQSMDVLRMAKQHAPAGTL 866
DF G ++K+ + +DV A NIETVE L VRD RA + Q+++ L+ KQ +P L
Sbjct: 176 DFAGINENIDKIINTKVDVIAQNIETVERLTHPVRDPRAGYWQTLNFLKYVKQKSP-NVL 234
Query: 867 TKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSKRHMPVAEYVTPEAFERYRL 1046
TKTS+M+G GET +++ KTM+ R+ GVD++T GQYM+P+K H+ V +VTP+ FE YR
Sbjct: 235 TKTSIMVGLGETDEEIYKTMDDARSVGVDIITLGQYMQPTKHHLSVERFVTPQQFEEYRK 294
Query: 1047 LGMEMGFRYVASGPMVRSSYKAGEYYIKSMIE 1142
+G+E GF VASGPMVRSSY+A + ++ ++
Sbjct: 295 VGLEKGFLEVASGPMVRSSYRADRVFKRNNLD 326
>sp|Q14IH3|LIPA_FRAT1 Lipoyl synthase OS=Francisella tularensis subsp.
tularensis (strain FSC 198) GN=lipA PE=3 SV=1
Length = 327
Score = 285 bits (728), Expect = 7e-076
Identities = 145/332 (43%), Positives = 212/332 (63%), Gaps = 14/332 (4%)
Frame = +3
Query: 162 LESLRARLADESPSLTDFIHGDTYSVEVGTKKKP-----LPKPKWMKESIPGGERYVQII 326
+ ++ ++ S TD HG ++V+ G + K + KP W+K + Y+++
Sbjct: 4 ISGIKVKVESGSKYTTD--HG-FHAVKDGIRNKKENAVHVRKPDWLKVQKQDSKEYLKVK 60
Query: 327 KKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILGDTCTRGCRFCNVKTSRTPPP 506
+ L TVCEEA+CPN+ ECWS G TATIM++G CTR C+FC+V T
Sbjct: 61 SITKKHKLSTVCEEARCPNINECWSHG-----TATIMLMGSVCTRACKFCSVDTGNPKGW 115
Query: 507 PDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAQTVQRLKTLKPEMLIEALVP 686
D +EP N AE++ G++YVV+TSVDRDDL D G+GH+A T+ +K L + +EAL P
Sbjct: 116 LDKDEPMNAAESVKLMGLEYVVLTSVDRDDLEDGGAGHYAATITAIKNLDENIKVEALTP 175
Query: 687 DFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRANFKQSMDVLRMAKQHAPAGTL 866
DF G ++K+ + +DV A NIETVE L VRD RA + Q+++ L+ KQ +P L
Sbjct: 176 DFAGINENIDKIINTKVDVIAQNIETVERLTHPVRDPRAGYWQTLNFLKYVKQKSP-NVL 234
Query: 867 TKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSKRHMPVAEYVTPEAFERYRL 1046
TKTS+M+G GET +++ KTM+ R+ GVD++T GQYM+P+K H+ V +VTP+ FE YR
Sbjct: 235 TKTSIMVGLGETDEEIYKTMDDARSVGVDIITLGQYMQPTKHHLSVERFVTPQQFEEYRK 294
Query: 1047 LGMEMGFRYVASGPMVRSSYKAGEYYIKSMIE 1142
+G+E GF VASGPMVRSSY+A + ++ ++
Sbjct: 295 VGLEKGFLEVASGPMVRSSYRADRVFKRNNLD 326
>sp|A0Q6Q2|LIPA_FRATN Lipoyl synthase OS=Francisella tularensis subsp. novicida
(strain U112) GN=lipA PE=3 SV=1
Length = 327
Score = 285 bits (728), Expect = 7e-076
Identities = 145/332 (43%), Positives = 212/332 (63%), Gaps = 14/332 (4%)
Frame = +3
Query: 162 LESLRARLADESPSLTDFIHGDTYSVEVGTKKKP-----LPKPKWMKESIPGGERYVQII 326
+ ++ ++ S TD HG ++V+ G + K + KP W+K + Y+++
Sbjct: 4 ISGIKVKVESGSKYTTD--HG-FHAVKDGIRNKKENAVHVRKPDWLKVQKQDSKEYLKVK 60
Query: 327 KKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILGDTCTRGCRFCNVKTSRTPPP 506
+ L TVCEEA+CPN+ ECWS G TATIM++G CTR C+FC+V T
Sbjct: 61 SITKKHKLSTVCEEARCPNINECWSHG-----TATIMLMGSVCTRACKFCSVDTGNPKGW 115
Query: 507 PDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAQTVQRLKTLKPEMLIEALVP 686
D +EP N AE++ G++YVV+TSVDRDDL D G+GH+A T+ +K L + +EAL P
Sbjct: 116 LDKDEPMNAAESVKLMGLEYVVLTSVDRDDLEDGGAGHYAATITAIKNLDENIKVEALTP 175
Query: 687 DFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRANFKQSMDVLRMAKQHAPAGTL 866
DF G ++K+ + +DV A NIETVE L VRD RA + Q+++ L+ KQ +P L
Sbjct: 176 DFAGINENIDKIINTKVDVIAQNIETVERLTHPVRDPRAGYWQTLNFLKYVKQKSP-NVL 234
Query: 867 TKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSKRHMPVAEYVTPEAFERYRL 1046
TKTS+M+G GET +++ KTM+ R+ GVD++T GQYM+P+K H+ V +VTP+ FE YR
Sbjct: 235 TKTSIMVGLGETDEEIYKTMDDARSVGVDIITLGQYMQPTKHHLSVERFVTPQQFEEYRK 294
Query: 1047 LGMEMGFRYVASGPMVRSSYKAGEYYIKSMIE 1142
+G+E GF VASGPMVRSSY+A + ++ ++
Sbjct: 295 VGLEKGFLEVASGPMVRSSYRADRVFKRNNLD 326
>sp|Q5NH21|LIPA_FRATT Lipoyl synthase OS=Francisella tularensis subsp.
tularensis GN=lipA PE=3 SV=1
Length = 327
Score = 285 bits (728), Expect = 7e-076
Identities = 145/332 (43%), Positives = 212/332 (63%), Gaps = 14/332 (4%)
Frame = +3
Query: 162 LESLRARLADESPSLTDFIHGDTYSVEVGTKKKP-----LPKPKWMKESIPGGERYVQII 326
+ ++ ++ S TD HG ++V+ G + K + KP W+K + Y+++
Sbjct: 4 ISGIKVKVESGSKYTTD--HG-FHAVKDGIRNKKENAVHVRKPDWLKVQKQDSKEYLKVK 60
Query: 327 KKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILGDTCTRGCRFCNVKTSRTPPP 506
+ L TVCEEA+CPN+ ECWS G TATIM++G CTR C+FC+V T
Sbjct: 61 SITKKHKLSTVCEEARCPNINECWSHG-----TATIMLMGSVCTRACKFCSVDTGNPKGW 115
Query: 507 PDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAQTVQRLKTLKPEMLIEALVP 686
D +EP N AE++ G++YVV+TSVDRDDL D G+GH+A T+ +K L + +EAL P
Sbjct: 116 LDKDEPMNAAESVKLMGLEYVVLTSVDRDDLEDGGAGHYAATITAIKNLDENIKVEALTP 175
Query: 687 DFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRANFKQSMDVLRMAKQHAPAGTL 866
DF G ++K+ + +DV A NIETVE L VRD RA + Q+++ L+ KQ +P L
Sbjct: 176 DFAGINENIDKIINTKVDVIAQNIETVERLTHPVRDPRAGYWQTLNFLKYVKQKSP-NVL 234
Query: 867 TKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSKRHMPVAEYVTPEAFERYRL 1046
TKTS+M+G GET +++ KTM+ R+ GVD++T GQYM+P+K H+ V +VTP+ FE YR
Sbjct: 235 TKTSIMVGLGETDEEIYKTMDDARSVGVDIITLGQYMQPTKHHLSVERFVTPQQFEEYRK 294
Query: 1047 LGMEMGFRYVASGPMVRSSYKAGEYYIKSMIE 1142
+G+E GF VASGPMVRSSY+A + ++ ++
Sbjct: 295 VGLEKGFLEVASGPMVRSSYRADRVFKRNNLD 326
>sp|A4IY90|LIPA_FRATW Lipoyl synthase OS=Francisella tularensis subsp.
tularensis (strain WY96-3418) GN=lipA PE=3 SV=1
Length = 327
Score = 285 bits (728), Expect = 7e-076
Identities = 145/332 (43%), Positives = 212/332 (63%), Gaps = 14/332 (4%)
Frame = +3
Query: 162 LESLRARLADESPSLTDFIHGDTYSVEVGTKKKP-----LPKPKWMKESIPGGERYVQII 326
+ ++ ++ S TD HG ++V+ G + K + KP W+K + Y+++
Sbjct: 4 ISGIKVKVESGSKYTTD--HG-FHAVKDGIRNKKENAVHVRKPDWLKVQKQDSKEYLKVK 60
Query: 327 KKLRDLNLHTVCEEAKCPNLGECWSGGETGTATATIMILGDTCTRGCRFCNVKTSRTPPP 506
+ L TVCEEA+CPN+ ECWS G TATIM++G CTR C+FC+V T
Sbjct: 61 SITKKHKLSTVCEEARCPNINECWSHG-----TATIMLMGSVCTRACKFCSVDTGNPKGW 115
Query: 507 PDPNEPNNVAEAIASWGVDYVVITSVDRDDLPDQGSGHFAQTVQRLKTLKPEMLIEALVP 686
D +EP N AE++ G++YVV+TSVDRDDL D G+GH+A T+ +K L + +EAL P
Sbjct: 116 LDKDEPMNAAESVKLMGLEYVVLTSVDRDDLEDGGAGHYAATITAIKNLDENIKVEALTP 175
Query: 687 DFRGDGGCVEKVAKSGLDVFAHNIETVEELQSFVRDHRANFKQSMDVLRMAKQHAPAGTL 866
DF G ++K+ + +DV A NIETVE L VRD RA + Q+++ L+ KQ +P L
Sbjct: 176 DFAGINENIDKIINTKVDVIAQNIETVERLTHPVRDPRAGYWQTLNFLKYVKQKSP-NVL 234
Query: 867 TKTSVMLGCGETPDQVVKTMEKVRAAGVDVMTFGQYMRPSKRHMPVAEYVTPEAFERYRL 1046
TKTS+M+G GET +++ KTM+ R+ GVD++T GQYM+P+K H+ V +VTP+ FE YR
Sbjct: 235 TKTSIMVGLGETDEEIYKTMDDARSVGVDIITLGQYMQPTKHHLSVERFVTPQQFEEYRK 294
Query: 1047 LGMEMGFRYVASGPMVRSSYKAGEYYIKSMIE 1142
+G+E GF VASGPMVRSSY+A + ++ ++
Sbjct: 295 VGLEKGFLEVASGPMVRSSYRADRVFKRNNLD 326
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 119,210,902,748
Number of Sequences: 518415
Number of Extensions: 119210902748
Number of Successful Extensions: 754584153
Number of sequences better than 0.0: 0
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