BLASTX 7.6.2
Query= UN30866 /QuerySize=1003
(1002 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN... 77 2e-013
sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevi... 75 5e-013
sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN... 75 6e-013
sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=R... 74 1e-012
sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevi... 74 1e-012
sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropica... 73 3e-012
sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabido... 71 1e-011
sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo... 70 2e-011
sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus ... 70 2e-011
sp|Q6GPV5|RN181_XENLA E3 ubiquitin-protein ligase RNF181 OS=Xeno... 70 3e-011
sp|Q5M974|RN181_XENTR E3 ubiquitin-protein ligase RNF181 OS=Xeno... 70 3e-011
sp|Q8NG27|PJA1_HUMAN E3 ubiquitin-protein ligase Praja-1 OS=Homo... 63 3e-009
sp|O55176|PJA1_MOUSE E3 ubiquitin-protein ligase Praja-1 OS=Mus ... 63 3e-009
sp|Q80U04|PJA2_MOUSE E3 ubiquitin-protein ligase Praja-2 OS=Mus ... 56 3e-007
sp|Q0IJ20|RN145_XENTR RING finger protein 145 OS=Xenopus tropica... 56 4e-007
sp|Q63364|PJA2_RAT E3 ubiquitin-protein ligase Praja-2 OS=Rattus... 55 9e-007
sp|O43164|PJA2_HUMAN E3 ubiquitin-protein ligase Praja-2 OS=Homo... 54 1e-006
sp|Q5R4R1|PJA2_PONAB E3 ubiquitin-protein ligase Praja-2 OS=Pong... 54 1e-006
>sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN=RNF126 PE=1
SV=1
Length = 326
Score = 77 bits (188), Expect = 2e-013
Identities = 40/105 (38%), Positives = 56/105 (53%), Gaps = 4/105 (3%)
Frame = +1
Query: 496 GTPPARRDAVEALADVII----LLPGMQCLVCLDDLEMGTVGKQMPCEHFFHSYCLLYWL 663
G PPA ++ ++AL V + + G++C VC DD +G +Q+PC H FH C++ WL
Sbjct: 201 GPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDYALGERVRQLPCNHLFHDGCIVPWL 260
Query: 664 QLHSSFPVCRCQLPTVEDETNGGGTDDGSSITSSSQGSENSDQEE 798
+ H S PVCR L TN G S +SSS S +S E
Sbjct: 261 EQHDSCPVCRKSLTGQNTATNPPGLTGVSFSSSSSSSSSSSPSNE 305
>sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevis GN=rnf126-b
PE=2 SV=1
Length = 312
Score = 75 bits (184), Expect = 5e-013
Identities = 40/106 (37%), Positives = 57/106 (53%), Gaps = 7/106 (6%)
Frame = +1
Query: 496 GTPPARRDAVEALADVIILLP----GMQCLVCLDDLEMGTVGKQMPCEHFFHSYCLLYWL 663
G PPA D ++AL + I G++C VC +D +G +Q+PC H FH+ C++ WL
Sbjct: 200 GPPPADTDKIQALPTIQITEEHVGFGLECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWL 259
Query: 664 QLHSSFPVCRCQLPTVEDETNGGGTDD---GSSITSSSQGSENSDQ 792
+ H + PVCR L TN G D SS TSSS + +D+
Sbjct: 260 EQHDTCPVCRKSLSGQNTATNPPGLTDMTFSSSSTSSSSSTSPTDE 305
>sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN=Rnf126 PE=1
SV=1
Length = 313
Score = 75 bits (183), Expect = 6e-013
Identities = 40/105 (38%), Positives = 57/105 (54%), Gaps = 5/105 (4%)
Frame = +1
Query: 496 GTPPARRDAVEALADVII----LLPGMQCLVCLDDLEMGTVGKQMPCEHFFHSYCLLYWL 663
G PPA ++ ++AL V + + G++C VC +D +G +Q+PC H FH C++ WL
Sbjct: 203 GPPPADKEKIQALPTVPVTEEHVGSGLECPVCKEDYALGESVRQLPCNHLFHDSCIVPWL 262
Query: 664 QLHSSFPVCRCQLPTVEDETNGGG-TDDGSSITSSSQGSENSDQE 795
+ H S PVCR L TN G T G S +SSS S + E
Sbjct: 263 EQHDSCPVCRKSLTGQNTATNPPGLTGVGFSSSSSSSSSSSPSNE 307
>sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=RNF126 PE=2
SV=1
Length = 313
Score = 74 bits (181), Expect = 1e-012
Identities = 40/105 (38%), Positives = 57/105 (54%), Gaps = 9/105 (8%)
Frame = +1
Query: 496 GTPPARRDAVEALADVII----LLPGMQCLVCLDDLEMGTVGKQMPCEHFFHSYCLLYWL 663
G PPA ++ ++AL V + + G++C VC DD +G +Q+PC H FH C++ WL
Sbjct: 204 GPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDYGLGEHVRQLPCNHLFHDGCIVPWL 263
Query: 664 QLHSSFPVCRCQLPTVEDETN-----GGGTDDGSSITSSSQGSEN 783
+ H S PVCR L T+ G SS +SSS G+EN
Sbjct: 264 EQHDSCPVCRKSLTGQNTATDPPGLAGVSFSSSSSSSSSSPGNEN 308
>sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevis GN=rnf126-a
PE=2 SV=1
Length = 312
Score = 74 bits (180), Expect = 1e-012
Identities = 38/106 (35%), Positives = 58/106 (54%), Gaps = 7/106 (6%)
Frame = +1
Query: 496 GTPPARRDAVEALADVII----LLPGMQCLVCLDDLEMGTVGKQMPCEHFFHSYCLLYWL 663
G PPA + ++AL + I + G++C VC +D +G +Q+PC H FH+ C++ WL
Sbjct: 200 GPPPADNEKIQALPTIQITEEHVGSGLECPVCKEDYTVGECVRQLPCNHLFHNDCIIPWL 259
Query: 664 QLHSSFPVCRCQLPTVEDETNGGGTDD---GSSITSSSQGSENSDQ 792
+ H + PVCR L TN G + SS TSSS + +D+
Sbjct: 260 EQHDTCPVCRKSLSGQNTATNPPGLSEMTFSSSSTSSSSSTSPTDE 305
>sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropicalis GN=rnf126
PE=2 SV=1
Length = 311
Score = 73 bits (177), Expect = 3e-012
Identities = 38/106 (35%), Positives = 58/106 (54%), Gaps = 7/106 (6%)
Frame = +1
Query: 496 GTPPARRDAVEALADVII----LLPGMQCLVCLDDLEMGTVGKQMPCEHFFHSYCLLYWL 663
G PPA + ++AL + I + G++C VC +D +G +Q+PC H FH+ C++ WL
Sbjct: 199 GPPPADTEKIQALPTIQITEEHVGSGLECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWL 258
Query: 664 QLHSSFPVCRCQLPTVEDETNGGGTDD---GSSITSSSQGSENSDQ 792
+ H + PVCR L TN G + SS TSSS + +D+
Sbjct: 259 EQHDTCPVCRKSLSGQNTATNPPGLTEMTFSSSSTSSSSSTSPTDE 304
>sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabidopsis thaliana
GN=CIP8 PE=1 SV=1
Length = 334
Score = 71 bits (172), Expect = 1e-011
Identities = 38/103 (36%), Positives = 54/103 (52%), Gaps = 4/103 (3%)
Frame = +1
Query: 490 RYGTPPARRDAVEALADVIILLPG----MQCLVCLDDLEMGTVGKQMPCEHFFHSYCLLY 657
R G PPA + A+EAL + M C VC D + MG GK++PC H +H C++
Sbjct: 227 RRGAPPAAKSAIEALETFEVSSSEGEMVMVCAVCKDGMVMGETGKKLPCGHCYHGDCIVP 286
Query: 658 WLQLHSSFPVCRCQLPTVEDETNGGGTDDGSSITSSSQGSENS 786
WL +S PVCR QL T + E S+++ S+ S +S
Sbjct: 287 WLGTRNSCPVCRFQLETDDAEYEEERKKRTSTVSDSAAASSSS 329
>sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo sapiens
GN=RNF115 PE=1 SV=2
Length = 304
Score = 70 bits (171), Expect = 2e-011
Identities = 36/103 (34%), Positives = 56/103 (54%), Gaps = 5/103 (4%)
Frame = +1
Query: 496 GTPPARRDAVEALADVIILLP----GMQCLVCLDDLEMGTVGKQMPCEHFFHSYCLLYWL 663
G PPA ++ + +L V + G++C VC +D + +Q+PC HFFHS C++ WL
Sbjct: 200 GPPPADKEKITSLPTVTVTQEQVDMGLECPVCKEDYTVEEEVRQLPCNHFFHSSCIVPWL 259
Query: 664 QLHSSFPVCRCQLPTVEDETNGGGTDDGSSITSSSQGSENSDQ 792
+LH + PVCR L ED T + + S+ S S+ D+
Sbjct: 260 ELHDTCPVCRKSL-NGEDSTRQSQSTEASASNRFSNDSQLHDR 301
>sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus musculus
GN=Rnf115 PE=1 SV=1
Length = 305
Score = 70 bits (171), Expect = 2e-011
Identities = 36/103 (34%), Positives = 57/103 (55%), Gaps = 5/103 (4%)
Frame = +1
Query: 496 GTPPARRDAVEALADVII----LLPGMQCLVCLDDLEMGTVGKQMPCEHFFHSYCLLYWL 663
G PPA ++ + +L V + + G++C VC +D + +Q+PC HFFHS C++ WL
Sbjct: 201 GPPPADKEKITSLPTVTVTQEQVNTGLECPVCKEDYTVEEKVRQLPCNHFFHSSCIVPWL 260
Query: 664 QLHSSFPVCRCQLPTVEDETNGGGTDDGSSITSSSQGSENSDQ 792
+LH + PVCR L ED T + + S+ S S+ D+
Sbjct: 261 ELHDTCPVCRKSL-NGEDSTRQTQSSEASASNRFSNDSQLHDR 302
>sp|Q6GPV5|RN181_XENLA E3 ubiquitin-protein ligase RNF181 OS=Xenopus laevis
GN=rnf181 PE=2 SV=1
Length = 156
Score = 70 bits (169), Expect = 3e-011
Identities = 38/94 (40%), Positives = 52/94 (55%), Gaps = 6/94 (6%)
Frame = +1
Query: 439 GPEFEAMLEDLTETDPRRYGTPPARRDAVEALADVIILL----PGMQCLVCLDDLEMGTV 606
G + + D TE D R PPA + VE+L V + ++C VCL + E G
Sbjct: 34 GMDIDLGAVDFTEWDQRL--PPPASKKVVESLPKVTVTPEQADAALKCPVCLLEFEEGET 91
Query: 607 GKQMPCEHFFHSYCLLYWLQLHSSFPVCRCQLPT 708
+Q+PCEH FHS C+L WL +S P+CR +LPT
Sbjct: 92 VRQLPCEHLFHSACILPWLGKTNSCPLCRHELPT 125
>sp|Q5M974|RN181_XENTR E3 ubiquitin-protein ligase RNF181 OS=Xenopus tropicalis
GN=rnf181 PE=2 SV=1
Length = 156
Score = 70 bits (169), Expect = 3e-011
Identities = 38/89 (42%), Positives = 50/89 (56%), Gaps = 6/89 (6%)
Frame = +1
Query: 466 DLTETDPRRYGTPPARRDAVEALADVIILL----PGMQCLVCLDDLEMGTVGKQMPCEHF 633
D TE D R PPA + VE+L V + ++C VCL + E G +Q+PCEH
Sbjct: 43 DFTEWDQRL--PPPAAKKVVESLPKVTVTPEQADAALKCPVCLLEFEEGETVRQLPCEHL 100
Query: 634 FHSYCLLYWLQLHSSFPVCRCQLPTVEDE 720
FHS C+L WL +S P+CR +LPT E
Sbjct: 101 FHSSCILPWLGKTNSCPLCRHELPTDSPE 129
>sp|Q8NG27|PJA1_HUMAN E3 ubiquitin-protein ligase Praja-1 OS=Homo sapiens
GN=PJA1 PE=1 SV=2
Length = 643
Score = 63 bits (152), Expect = 3e-009
Identities = 25/74 (33%), Positives = 42/74 (56%), Gaps = 6/74 (8%)
Frame = +1
Query: 502 PPARRDAVEALADVII------LLPGMQCLVCLDDLEMGTVGKQMPCEHFFHSYCLLYWL 663
PPA +++++AL ++++ + M C +C + G V ++PC H+FH C+ WL
Sbjct: 567 PPASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYFHKPCVSIWL 626
Query: 664 QLHSSFPVCRCQLP 705
Q + PVCRC P
Sbjct: 627 QKSGTCPVCRCMFP 640
>sp|O55176|PJA1_MOUSE E3 ubiquitin-protein ligase Praja-1 OS=Mus musculus
GN=Pja1 PE=1 SV=3
Length = 578
Score = 63 bits (152), Expect = 3e-009
Identities = 25/74 (33%), Positives = 42/74 (56%), Gaps = 6/74 (8%)
Frame = +1
Query: 502 PPARRDAVEALADVII------LLPGMQCLVCLDDLEMGTVGKQMPCEHFFHSYCLLYWL 663
PPA +++++AL ++++ + M C +C + G V ++PC H+FH C+ WL
Sbjct: 502 PPASKESIDALPEILVTEDHGAVGQEMCCPICCSEYVKGEVATELPCHHYFHKPCVSIWL 561
Query: 664 QLHSSFPVCRCQLP 705
Q + PVCRC P
Sbjct: 562 QKSGTCPVCRCMFP 575
>sp|Q80U04|PJA2_MOUSE E3 ubiquitin-protein ligase Praja-2 OS=Mus musculus
GN=Pja2 PE=1 SV=2
Length = 707
Score = 56 bits (134), Expect = 3e-007
Identities = 26/103 (25%), Positives = 51/103 (49%), Gaps = 8/103 (7%)
Frame = +1
Query: 502 PPARRDAVEALADVIIL----LPGMQ--CLVCLDDLEMGTVGKQMPCEHFFHSYCLLYWL 663
PPA +++++ L + ++L G + C +C + + ++PC HFFH C+ WL
Sbjct: 605 PPASKESIDGLPETLVLEDHTAIGQEQCCPICCSEYIKDDIATELPCHHFFHKPCVSIWL 664
Query: 664 QLHSSFPVCRCQLPTVEDETNGGGTDDGSSITSSSQGSENSDQ 792
Q + PVCR P + + + D +S ++N+++
Sbjct: 665 QKSGTCPVCRRHFPPAVIDASAAASSDPD--PDASPANDNAEE 705
>sp|Q0IJ20|RN145_XENTR RING finger protein 145 OS=Xenopus tropicalis GN=rnf145
PE=2 SV=1
Length = 695
Score = 56 bits (133), Expect = 4e-007
Identities = 35/119 (29%), Positives = 52/119 (43%), Gaps = 19/119 (15%)
Frame = +1
Query: 511 RRDAVEALADVIILLPGMQ------CLVCLDDLEMGTVGKQMPCEHFFHSYCLLYWLQLH 672
RRDAV + + + C +C D+ + PC HFFH CL WL +
Sbjct: 512 RRDAVNKIKSLPVATKEQLEQHNDICSICYQDMNSAVI---TPCSHFFHPGCLKKWLYVQ 568
Query: 673 SSFPVCRCQLPTVEDETNGGGTDDGSSITSSSQGSEN-------SDQEEEEDPMAA*PS 828
+ P+C CQL ++ + G + GSS S+ S S E +P+AA P+
Sbjct: 569 ETCPLCHCQLKSLSQQATG---ESGSSTNPVSEQSATNPPLGPVSRAEVTTEPLAAVPT 624
>sp|Q63364|PJA2_RAT E3 ubiquitin-protein ligase Praja-2 OS=Rattus norvegicus
GN=Pja2 PE=2 SV=1
Length = 707
Score = 55 bits (130), Expect = 9e-007
Identities = 25/103 (24%), Positives = 51/103 (49%), Gaps = 8/103 (7%)
Frame = +1
Query: 502 PPARRDAVEALADVIIL----LPGMQ--CLVCLDDLEMGTVGKQMPCEHFFHSYCLLYWL 663
PPA +++++ L + ++L G + C +C + + ++PC HFFH C+ WL
Sbjct: 605 PPASKESIDGLPETLVLEDHTAIGQEQCCPICCSEYIKDDIATELPCHHFFHKPCVSIWL 664
Query: 664 QLHSSFPVCRCQLPTVEDETNGGGTDDGSSITSSSQGSENSDQ 792
Q + PVCR P + + + + +S ++N+++
Sbjct: 665 QKSGTCPVCRRHFPPAVIDASAAASSEPD--LDASPANDNAEE 705
>sp|O43164|PJA2_HUMAN E3 ubiquitin-protein ligase Praja-2 OS=Homo sapiens
GN=PJA2 PE=1 SV=4
Length = 708
Score = 54 bits (129), Expect = 1e-006
Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 6/87 (6%)
Frame = +1
Query: 502 PPARRDAVEALADVIIL----LPGMQ--CLVCLDDLEMGTVGKQMPCEHFFHSYCLLYWL 663
PPA +++++ L + ++L G + C +C + + ++PC HFFH C+ WL
Sbjct: 606 PPASKESIDGLPETLVLEDHTAIGQEQCCPICCSEYIKDDIATELPCHHFFHKPCVSIWL 665
Query: 664 QLHSSFPVCRCQLPTVEDETNGGGTDD 744
Q + PVCR P E + + +
Sbjct: 666 QKSGTCPVCRRHFPPAVIEASAAPSSE 692
>sp|Q5R4R1|PJA2_PONAB E3 ubiquitin-protein ligase Praja-2 OS=Pongo abelii
GN=PJA2 PE=2 SV=1
Length = 708
Score = 54 bits (129), Expect = 1e-006
Identities = 24/87 (27%), Positives = 43/87 (49%), Gaps = 6/87 (6%)
Frame = +1
Query: 502 PPARRDAVEALADVIIL----LPGMQ--CLVCLDDLEMGTVGKQMPCEHFFHSYCLLYWL 663
PPA +++++ L + ++L G + C +C + + ++PC HFFH C+ WL
Sbjct: 606 PPASKESIDGLPETLVLEDHTAIGQEQCCPICCSEYIKDDIATELPCHHFFHKPCVSIWL 665
Query: 664 QLHSSFPVCRCQLPTVEDETNGGGTDD 744
Q + PVCR P E + + +
Sbjct: 666 QKSGTCPVCRRHFPPAVIEASAAPSSE 692
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 126,067,222,631
Number of Sequences: 518415
Number of Extensions: 126067222631
Number of Successful Extensions: 789442336
Number of sequences better than 0.0: 0
|
