BLASTX 7.6.2
Query= UN31357 /QuerySize=783
(782 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8N5S9|KKCC1_HUMAN Calcium/calmodulin-dependent protein kinas... 140 1e-032
sp|Q8VBY2|KKCC1_MOUSE Calcium/calmodulin-dependent protein kinas... 139 2e-032
sp|P97756|KKCC1_RAT Calcium/calmodulin-dependent protein kinase ... 136 2e-031
sp|Q96RR4|KKCC2_HUMAN Calcium/calmodulin-dependent protein kinas... 132 2e-030
sp|Q8C078|KKCC2_MOUSE Calcium/calmodulin-dependent protein kinas... 132 2e-030
sp|O88831|KKCC2_RAT Calcium/calmodulin-dependent protein kinase ... 132 2e-030
sp|B4KYX8|PLK4_DROMO Serine/threonine-protein kinase PLK4 OS=Dro... 124 1e-027
sp|B4LDJ6|PLK4_DROVI Serine/threonine-protein kinase PLK4 OS=Dro... 123 2e-027
sp|Q0GGW5|STK11_CHICK Serine/threonine-protein kinase 11 OS=Gall... 123 2e-027
sp|B4MXR8|PLK4_DROWI Serine/threonine-protein kinase PLK4 OS=Dro... 122 3e-027
sp|B4J3F1|PLK4_DROGR Serine/threonine-protein kinase PLK4 OS=Dro... 122 4e-027
sp|Q91604|STK11_XENLA Serine/threonine-protein kinase 11 OS=Xeno... 122 4e-027
sp|Q38997|KIN10_ARATH SNF1-related protein kinase catalytic subu... 121 9e-027
sp|Q9WTK7|STK11_MOUSE Serine/threonine-protein kinase 11 OS=Mus ... 119 2e-026
sp|Q76P07|Y7165_DICDI Probable serine/threonine-protein kinase D... 115 4e-025
sp|Q16W24|PLK4_AEDAE Serine/threonine-protein kinase PLK4 OS=Aed... 111 9e-024
sp|Q2TA06|STK6_BOVIN Serine/threonine-protein kinase 6 OS=Bos ta... 108 5e-023
sp|Q9QYZ3|SMK2B_MOUSE Sperm motility kinase 2B OS=Mus musculus G... 106 2e-022
sp|A5GFW1|STK6_PIG Serine/threonine-protein kinase 6 OS=Sus scro... 106 3e-022
sp|Q9QYZ5|SMK3_MOUSE Sperm motility kinase 3 OS=Mus musculus GN=... 105 4e-022
>sp|Q8N5S9|KKCC1_HUMAN Calcium/calmodulin-dependent protein kinase kinase 1
OS=Homo sapiens GN=CAMKK1 PE=1 SV=2
Length = 505
Score = 140 bits (352), Expect = 1e-032
Identities = 78/188 (41%), Positives = 109/188 (57%), Gaps = 9/188 (4%)
Frame = +3
Query: 3 DIVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFT 182
D++ GL YLH ++H DIKP NLL+ G VKI DF VS F+ +D QL + GTP F
Sbjct: 258 DVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFM 317
Query: 183 APECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPD--G 356
APE SG ++SG+A D WA GVTLY + G+ PF+ D + + KI N P+ P+
Sbjct: 318 APEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILALHRKIKNEPVVFPEEPE 377
Query: 357 LNPFLRDLIEGLLCKNPSERMTLKNVLEHPWVMEE-EGHVPEYICCCERRNSAVKIEQEE 533
++ L+DLI +L KNP R+ + ++ HPWV + E +P E + +V +E E
Sbjct: 378 ISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEPLPS-----EEEHCSV-VEVTE 431
Query: 534 EEANGDVR 557
EE VR
Sbjct: 432 EEVKNSVR 439
>sp|Q8VBY2|KKCC1_MOUSE Calcium/calmodulin-dependent protein kinase kinase 1
OS=Mus musculus GN=Camkk1 PE=1 SV=1
Length = 505
Score = 139 bits (349), Expect = 2e-032
Identities = 75/179 (41%), Positives = 105/179 (58%), Gaps = 5/179 (2%)
Frame = +3
Query: 3 DIVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFT 182
DI+ GL YLH ++H DIKP NLL+ G VKI DF VS F+ +D QL + GTP F
Sbjct: 258 DIILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFM 317
Query: 183 APECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPD--G 356
APE SG ++SG+A D WA GVTLY + G+ PF+ D + + KI N + P+
Sbjct: 318 APEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDYILTLHRKIKNEAVVFPEEPE 377
Query: 357 LNPFLRDLIEGLLCKNPSERMTLKNVLEHPWVMEEEGHVPEYICCCERRNSAVKIEQEE 533
++ L+DLI +L KNP R+ + ++ HPWV + H E + E S V++ +EE
Sbjct: 378 VSEDLKDLILRMLDKNPETRIGVSDIKLHPWVTK---HGEEPLPSEEEHCSVVEVTEEE 433
>sp|P97756|KKCC1_RAT Calcium/calmodulin-dependent protein kinase kinase 1
OS=Rattus norvegicus GN=Camkk1 PE=1 SV=1
Length = 505
Score = 136 bits (341), Expect = 2e-031
Identities = 73/179 (40%), Positives = 105/179 (58%), Gaps = 5/179 (2%)
Frame = +3
Query: 3 DIVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFT 182
DI+ GL YLH ++H DIKP NLL+ G VKI DF VS F+ +D QL + GTP F
Sbjct: 258 DIILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFM 317
Query: 183 APECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPD--G 356
APE +G ++SG+A D WA GVTLY + G+ PF+ + + + KI N + P+
Sbjct: 318 APEAISDTGQSFSGKALDVWATGVTLYCFVYGKCPFIDEYILALHRKIKNEAVVFPEEPE 377
Query: 357 LNPFLRDLIEGLLCKNPSERMTLKNVLEHPWVMEEEGHVPEYICCCERRNSAVKIEQEE 533
++ L+DLI +L KNP R+ + ++ HPWV + H E + E S V++ +EE
Sbjct: 378 VSEELKDLILKMLDKNPETRIGVSDIKLHPWVTK---HGEEPLPSEEEHCSVVEVTEEE 433
>sp|Q96RR4|KKCC2_HUMAN Calcium/calmodulin-dependent protein kinase kinase 2
OS=Homo sapiens GN=CAMKK2 PE=1 SV=1
Length = 588
Score = 132 bits (332), Expect = 2e-030
Identities = 72/181 (39%), Positives = 100/181 (55%), Gaps = 5/181 (2%)
Frame = +3
Query: 3 DIVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFT 182
D++ G+ YLH +IH DIKP NLLV G +KI DF VS FK D L + GTP F
Sbjct: 295 DLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFM 354
Query: 183 APECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPD--G 356
APE + +SG+A D WA+GVTLY + GQ PF+ + + + KI + L PD
Sbjct: 355 APESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPD 414
Query: 357 LNPFLRDLIEGLLCKNPSERMTLKNVLEHPWVMEEEGHVPEYICCCERRNSAVKIEQEEE 536
+ L+DLI +L KNP R+ + + HPWV H E + + + V++ +EE
Sbjct: 415 IAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTR---HGAEPLPSEDENCTLVEVTEEEV 471
Query: 537 E 539
E
Sbjct: 472 E 472
>sp|Q8C078|KKCC2_MOUSE Calcium/calmodulin-dependent protein kinase kinase 2
OS=Mus musculus GN=Camkk2 PE=1 SV=2
Length = 588
Score = 132 bits (332), Expect = 2e-030
Identities = 72/181 (39%), Positives = 100/181 (55%), Gaps = 5/181 (2%)
Frame = +3
Query: 3 DIVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFT 182
D++ G+ YLH +IH DIKP NLLV G +KI DF VS FK D L + GTP F
Sbjct: 295 DLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFM 354
Query: 183 APECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPD--G 356
APE + +SG+A D WA+GVTLY + GQ PF+ + + + KI + L PD
Sbjct: 355 APESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPD 414
Query: 357 LNPFLRDLIEGLLCKNPSERMTLKNVLEHPWVMEEEGHVPEYICCCERRNSAVKIEQEEE 536
+ L+DLI +L KNP R+ + + HPWV H E + + + V++ +EE
Sbjct: 415 IAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTR---HGAEPLPSEDENCTLVEVTEEEV 471
Query: 537 E 539
E
Sbjct: 472 E 472
>sp|O88831|KKCC2_RAT Calcium/calmodulin-dependent protein kinase kinase 2
OS=Rattus norvegicus GN=Camkk2 PE=1 SV=1
Length = 587
Score = 132 bits (332), Expect = 2e-030
Identities = 72/181 (39%), Positives = 100/181 (55%), Gaps = 5/181 (2%)
Frame = +3
Query: 3 DIVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFT 182
D++ G+ YLH +IH DIKP NLLV G +KI DF VS FK D L + GTP F
Sbjct: 294 DLIKGIEYLHYQKIIHRDIKPSNLLVGEDGHIKIADFGVSNEFKGSDALLSNTVGTPAFM 353
Query: 183 APECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPD--G 356
APE + +SG+A D WA+GVTLY + GQ PF+ + + + KI + L PD
Sbjct: 354 APESLSETRKIFSGKALDVWAMGVTLYCFVFGQCPFMDERIMCLHSKIKSQALEFPDQPD 413
Query: 357 LNPFLRDLIEGLLCKNPSERMTLKNVLEHPWVMEEEGHVPEYICCCERRNSAVKIEQEEE 536
+ L+DLI +L KNP R+ + + HPWV H E + + + V++ +EE
Sbjct: 414 IAEDLKDLITRMLDKNPESRIVVPEIKLHPWVTR---HGAEPLPSEDENCTLVEVTEEEV 470
Query: 537 E 539
E
Sbjct: 471 E 471
>sp|B4KYX8|PLK4_DROMO Serine/threonine-protein kinase PLK4 OS=Drosophila
mojavensis GN=SAK PE=3 SV=1
Length = 778
Score = 124 bits (309), Expect = 1e-027
Identities = 65/159 (40%), Positives = 102/159 (64%), Gaps = 3/159 (1%)
Frame = +3
Query: 6 IVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFTA 185
+V GL+YLH+HN++H DI NLL++ VKI DF ++ K D++ GTP + +
Sbjct: 123 VVDGLLYLHSHNIMHRDISLSNLLLSKDMHVKIADFGLATQLKRPDERHMTMCGTPNYIS 182
Query: 186 PECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPDGLNP 365
PE +VS +++ G AD W+VG LY +++G+ PF D +Q T +K+V++ T+P L+
Sbjct: 183 PE--VVSHMSH-GLPADLWSVGCMLYTLLVGRPPFDTDAVQSTLNKVVHSDYTMPSHLSY 239
Query: 366 FLRDLIEGLLCKNPSERMTLKNVLEHPWVMEEEGHVPEY 482
RDLI+ LL KNP ER++L+ VL HP++++ G Y
Sbjct: 240 EARDLIDKLLRKNPHERISLEQVLRHPFMLKVGGSTISY 278
>sp|B4LDJ6|PLK4_DROVI Serine/threonine-protein kinase PLK4 OS=Drosophila virilis
GN=SAK PE=3 SV=1
Length = 781
Score = 123 bits (307), Expect = 2e-027
Identities = 66/159 (41%), Positives = 100/159 (62%), Gaps = 3/159 (1%)
Frame = +3
Query: 6 IVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFTA 185
+V GL+YLH+HN++H DI NLL++ VKI DF ++ K D++ GTP + +
Sbjct: 123 VVDGLLYLHSHNIMHRDISMSNLLLSKDMHVKIADFGLATQLKRPDERHMTMCGTPNYIS 182
Query: 186 PECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPDGLNP 365
PE +VS ++ G AD W+VG LY +++G+ PF D +Q T +K+V + TIP L+
Sbjct: 183 PE--VVSHQSH-GLPADLWSVGCMLYTLLVGRPPFDTDAVQSTLNKVVQSDYTIPGHLSY 239
Query: 366 FLRDLIEGLLCKNPSERMTLKNVLEHPWVMEEEGHVPEY 482
RDLI+ LL KNP ER++L+ VL HP++++ G Y
Sbjct: 240 EARDLIDKLLRKNPHERISLEQVLRHPFMVKAGGSTISY 278
>sp|Q0GGW5|STK11_CHICK Serine/threonine-protein kinase 11 OS=Gallus gallus
GN=STK11 PE=2 SV=1
Length = 440
Score = 123 bits (307), Expect = 2e-027
Identities = 59/151 (39%), Positives = 93/151 (61%), Gaps = 5/151 (3%)
Frame = +3
Query: 6 IVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKD--DDDQLRRSPGTPVF 179
++ GL YLH+ ++H DIKP NLL+T++GT+KI D V++ +DD R S G+P F
Sbjct: 160 LIDGLEYLHSQGIVHKDIKPGNLLLTTNGTLKISDLGVAEALHPFAEDDTCRTSQGSPAF 219
Query: 180 TAPECCLVSGI-TYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPDG 356
PE + +G+ T+SG D W+ GVTLY++ G YPF D + ++ I TIP+
Sbjct: 220 QPPE--IANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGDFTIPED 277
Query: 357 LNPFLRDLIEGLLCKNPSERMTLKNVLEHPW 449
P L DL+ G+L +P++R +++ + +H W
Sbjct: 278 CGPPLSDLLRGMLEYDPAKRFSIQQIRQHNW 308
>sp|B4MXR8|PLK4_DROWI Serine/threonine-protein kinase PLK4 OS=Drosophila
willistoni GN=SAK PE=3 SV=1
Length = 787
Score = 122 bits (305), Expect = 3e-027
Identities = 66/158 (41%), Positives = 99/158 (62%), Gaps = 3/158 (1%)
Frame = +3
Query: 6 IVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFTA 185
+VAGL+YLH+HN++H DI NLL++ VKI DF ++ K D++ GTP F +
Sbjct: 123 VVAGLLYLHSHNIMHRDISLSNLLLSKDMHVKIADFGLATQLKRPDEKHMTMCGTPNFIS 182
Query: 186 PECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPDGLNP 365
PE +VS +++ G AAD W+VG LY +++G+ PF D +Q T +K+V + +P L+
Sbjct: 183 PE--VVSRLSH-GLAADVWSVGCLLYTLVVGRPPFDTDAVQSTLNKVVMSEFIMPTHLSF 239
Query: 366 FLRDLIEGLLCKNPSERMTLKNVLEHPWVMEEEGHVPE 479
DLIE LL KNP ER++L+ VL HP++ + E
Sbjct: 240 EACDLIEKLLKKNPHERISLEQVLRHPFMSKRSAGAEE 277
>sp|B4J3F1|PLK4_DROGR Serine/threonine-protein kinase PLK4 OS=Drosophila
grimshawi GN=SAK PE=3 SV=1
Length = 762
Score = 122 bits (304), Expect = 4e-027
Identities = 65/154 (42%), Positives = 100/154 (64%), Gaps = 3/154 (1%)
Frame = +3
Query: 6 IVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFTA 185
+V GL+YLH+HN++H DI NLL++ VKI DF ++ K D++ GTP + +
Sbjct: 123 VVDGLLYLHSHNIMHRDISLSNLLLSRDMHVKIADFGLATQLKRPDERHMTMCGTPNYIS 182
Query: 186 PECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPDGLNP 365
PE +VS +++ G AD W+VG LY +++G+ PF D +Q T +K+V + T+P L+
Sbjct: 183 PE--VVSHMSH-GLPADLWSVGCMLYTLLVGRPPFDTDAVQSTLNKVVLSDYTMPSHLSY 239
Query: 366 FLRDLIEGLLCKNPSERMTLKNVLEHPWVMEEEG 467
RDLIE LL KNP ER++L+ VL HP++++ G
Sbjct: 240 EARDLIEKLLRKNPHERISLEQVLRHPFMVKAGG 273
>sp|Q91604|STK11_XENLA Serine/threonine-protein kinase 11 OS=Xenopus laevis
GN=stk11 PE=1 SV=1
Length = 432
Score = 122 bits (304), Expect = 4e-027
Identities = 58/159 (36%), Positives = 95/159 (59%), Gaps = 5/159 (3%)
Frame = +3
Query: 6 IVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKD--DDDQLRRSPGTPVF 179
++ GL YLH+ ++H DIKP NLL+T+ GT+KI D V++ + D R S G+P F
Sbjct: 163 LIDGLEYLHSQGIVHKDIKPGNLLLTTDGTLKISDLGVAEALHPFAEGDTCRTSQGSPAF 222
Query: 180 TAPECCLVSGI-TYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPDG 356
PE + +G+ T+SG D W+ GVTLY++ G YPF D + ++ I +IP+
Sbjct: 223 QPPE--IANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGKGDYSIPEE 280
Query: 357 LNPFLRDLIEGLLCKNPSERMTLKNVLEHPWVMEEEGHV 473
P L DL+ G+L +P++R +++ + +H W ++ H+
Sbjct: 281 CGPLLSDLLRGMLEYDPAKRFSIQQIRQHNWFRKKHPHM 319
>sp|Q38997|KIN10_ARATH SNF1-related protein kinase catalytic subunit alpha KIN10
OS=Arabidopsis thaliana GN=KIN10 PE=1 SV=2
Length = 535
Score = 121 bits (301), Expect = 9e-027
Identities = 64/177 (36%), Positives = 103/177 (58%), Gaps = 8/177 (4%)
Frame = +3
Query: 6 IVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFTA 185
I++G+ Y H + V+H D+KP+NLL+ S VKI DF +S + + D L+ S G+P + A
Sbjct: 149 IISGVEYCHRNMVVHRDLKPENLLLDSKCNVKIADFGLSNIMR-DGHFLKTSCGSPNYAA 207
Query: 186 PECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPDGLNP 365
PE ++SG Y+G D W+ GV LY ++ G PF + + + + KI T+P L+P
Sbjct: 208 PE--VISGKLYAGPEVDVWSCGVILYALLCGTLPFDDENIPNLFKKIKGGIYTLPSHLSP 265
Query: 366 FLRDLIEGLLCKNPSERMTLKNVLEHPWVMEEEGHVPEYICC--CERRNSAVKIEQE 530
RDLI +L +P +R+T+ + +HPW + H+P Y+ + A KI++E
Sbjct: 266 GARDLIPRMLVVDPMKRVTIPEIRQHPWF---QAHLPRYLAVPPPDTVQQAKKIDEE 319
>sp|Q9WTK7|STK11_MOUSE Serine/threonine-protein kinase 11 OS=Mus musculus
GN=Stk11 PE=1 SV=1
Length = 436
Score = 119 bits (298), Expect = 2e-026
Identities = 59/151 (39%), Positives = 90/151 (59%), Gaps = 5/151 (3%)
Frame = +3
Query: 6 IVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKD--DDDQLRRSPGTPVF 179
++ GL YLH+ ++H DIKP NLL+T++GT+KI D V++ DD R S G+P F
Sbjct: 160 LIDGLEYLHSQGIVHKDIKPGNLLLTTNGTLKISDLGVAEALHPFAVDDTCRTSQGSPAF 219
Query: 180 TAPECCLVSGI-TYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPDG 356
PE + +G+ T+SG D W+ GVTLY++ G YPF D + ++ I TIP
Sbjct: 220 QPPE--IANGLDTFSGFKVDIWSAGVTLYNITTGLYPFEGDNIYKLFENIGRGDFTIPCD 277
Query: 357 LNPFLRDLIEGLLCKNPSERMTLKNVLEHPW 449
P L DL+ G+L P++R +++ + +H W
Sbjct: 278 CGPPLSDLLRGMLEYEPAKRFSIRQIRQHSW 308
>sp|Q76P07|Y7165_DICDI Probable serine/threonine-protein kinase DDB_G0277165
OS=Dictyostelium discoideum GN=DDB_G0277165 PE=3 SV=1
Length = 833
Score = 115 bits (287), Expect = 4e-025
Identities = 54/148 (36%), Positives = 92/148 (62%), Gaps = 3/148 (2%)
Frame = +3
Query: 6 IVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFTA 185
I+ GL Y H+ N+ H D+KP+NLL++ +KI DF + + + D L S G+P + +
Sbjct: 117 IIIGLEYCHSRNICHRDLKPENLLLSGDKRIKIADFGMGSIVR-KDMLLHTSCGSPHYAS 175
Query: 186 PECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPDGLNP 365
PE +VSGI Y G+ AD W+ GV LY ++ G+ PF + ++ +K+ N ++P ++
Sbjct: 176 PE--VVSGIDYDGQKADVWSCGVILYALLTGKLPFDDENIRRLLNKVKNGAFSMPPYIHK 233
Query: 366 FLRDLIEGLLCKNPSERMTLKNVLEHPW 449
+DL+ +L +PS+R+++K + EHPW
Sbjct: 234 DAQDLLTKMLTVDPSKRISIKEIKEHPW 261
>sp|Q16W24|PLK4_AEDAE Serine/threonine-protein kinase PLK4 OS=Aedes aegypti
GN=SAK PE=3 SV=1
Length = 769
Score = 111 bits (275), Expect = 9e-024
Identities = 58/149 (38%), Positives = 90/149 (60%), Gaps = 3/149 (2%)
Frame = +3
Query: 6 IVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFTA 185
+V GL+YLH+H+++H D+ NLL+T TVKI DF ++ D++ GTP + +
Sbjct: 118 VVDGLLYLHSHHILHRDMSLANLLLTKQMTVKISDFGLATQLTRPDEKHMTLCGTPNYIS 177
Query: 186 PECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPDGLNP 365
PE V+ G AD W +G LY ++G+ PF + ++ T K+V + TIP ++
Sbjct: 178 PE---VASRASHGLPADVWGLGCMLYTFLVGKPPFDTEGVKSTLTKVVMSNYTIPPYISS 234
Query: 366 FLRDLIEGLLCKNPSERMTLKNVLEHPWV 452
RDLI+ LL KNP+ER+ L VL+HP++
Sbjct: 235 EARDLIDQLLKKNPAERIKLDQVLQHPFM 263
>sp|Q2TA06|STK6_BOVIN Serine/threonine-protein kinase 6 OS=Bos taurus GN=AURKA
PE=2 SV=1
Length = 402
Score = 108 bits (269), Expect = 5e-023
Identities = 62/151 (41%), Positives = 86/151 (56%), Gaps = 5/151 (3%)
Frame = +3
Query: 3 DIVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFT 182
++ L Y H+ VIH DIKP+NLL+ S+G +KI DF S + GT +
Sbjct: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYL 296
Query: 183 APECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPDGLN 362
PE ++ G + + D W++GV Y ++G+ PF ADT Q+TY +I T PD +
Sbjct: 297 PPE--MIEGRMHDEK-VDLWSLGVLCYEFLVGKPPFEADTYQETYRRISRVEFTFPDCVP 353
Query: 363 PFLRDLIEGLLCKNPSERMTLKNVLEHPWVM 455
RDLI LL NPS+R TLK VLEHPW++
Sbjct: 354 EGARDLISRLLKHNPSQRPTLKEVLEHPWII 384
>sp|Q9QYZ3|SMK2B_MOUSE Sperm motility kinase 2B OS=Mus musculus GN=Smok2b PE=2
SV=1
Length = 484
Score = 106 bits (263), Expect = 2e-022
Identities = 59/158 (37%), Positives = 84/158 (53%), Gaps = 3/158 (1%)
Frame = +3
Query: 6 IVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFTA 185
+++ + Y H ++H D+KPDN++V G VKI DF + K +L GT F+A
Sbjct: 111 LLSAMNYCHNQGIVHRDLKPDNIMVEKDGKVKIIDFGLGTQVK-PGQKLNLFCGTYPFSA 169
Query: 186 PECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPDGLNP 365
PE L Y G D W +GV LY M+ G+ PF A ++Q +I+ +P L+
Sbjct: 170 PEVLL--SRPYDGPKIDVWTLGVVLYFMVTGKVPFDAASIQKLVRQILAGKYFVPSRLSV 227
Query: 366 FLRDLIEGLLCKNPSERMTLKNVLEHPWVMEEEGHVPE 479
LRDLI L+ NP R T+ V+ HPWV E G P+
Sbjct: 228 ELRDLISLLMTANPKLRPTVAEVMVHPWVTEGSGVFPD 265
>sp|A5GFW1|STK6_PIG Serine/threonine-protein kinase 6 OS=Sus scrofa GN=AURKA
PE=3 SV=1
Length = 402
Score = 106 bits (262), Expect = 3e-022
Identities = 61/150 (40%), Positives = 84/150 (56%), Gaps = 5/150 (3%)
Frame = +3
Query: 3 DIVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFT 182
++ L Y H+ VIH DIKP+NLL+ S+G +KI DF S + GT +
Sbjct: 239 ELANALSYCHSKRVIHRDIKPENLLLGSAGELKIADFGWS--VHAPSSRRTTLCGTLDYL 296
Query: 183 APECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPDGLN 362
PE ++ G + + D W++GV Y ++G+ PF A+T Q+TY +I T PD +
Sbjct: 297 PPE--MIEGRMHDEK-VDLWSLGVLCYEFLVGKPPFEANTYQETYKRISRVEFTFPDFVP 353
Query: 363 PFLRDLIEGLLCKNPSERMTLKNVLEHPWV 452
RDLI LL NPS R TLK VLEHPW+
Sbjct: 354 EGARDLISRLLKHNPSHRPTLKEVLEHPWI 383
>sp|Q9QYZ5|SMK3_MOUSE Sperm motility kinase 3 OS=Mus musculus GN=Smok3a PE=2
SV=1
Length = 504
Score = 105 bits (261), Expect = 4e-022
Identities = 57/158 (36%), Positives = 85/158 (53%), Gaps = 3/158 (1%)
Frame = +3
Query: 6 IVAGLMYLHAHNVIHGDIKPDNLLVTSSGTVKIGDFSVSQVFKDDDDQLRRSPGTPVFTA 185
+++ + Y H ++H D+KPDN++V G VKI DF + K +L GT F+A
Sbjct: 131 LLSAMNYCHNQGIVHRDLKPDNIMVEKDGKVKIIDFGLGTKVK-PGQKLNLFCGTYPFSA 189
Query: 186 PECCLVSGITYSGRAADTWAVGVTLYHMILGQYPFLADTLQDTYDKIVNNPLTIPDGLNP 365
PE L Y G D W +GV LY M+ G+ PF A +++ +I+ +IP L+
Sbjct: 190 PEVLL--STPYDGPKIDVWTLGVVLYFMVTGKIPFDACSIKKLVKRILAGKYSIPSRLSA 247
Query: 366 FLRDLIEGLLCKNPSERMTLKNVLEHPWVMEEEGHVPE 479
L+DL+ L+ NP R T+ V+ HPWV E G P+
Sbjct: 248 ELQDLLSLLMTANPKLRPTVAEVMVHPWVTEGSGVFPD 285
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 126,067,222,631
Number of Sequences: 518415
Number of Extensions: 126067222631
Number of Successful Extensions: 789442336
Number of sequences better than 0.0: 0
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