BLASTX 7.6.2
Query= UN32418 /QuerySize=1176
(1175 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9U2R0|BIN3D_CAEEL Probable methyltransferase Y17G7B.18 OS=Ca... 193 3e-048
sp|Q7L2J0|MEPCE_HUMAN 7SK snRNA methylphosphate capping enzyme O... 116 3e-025
sp|Q8K3A9|MEPCE_MOUSE 7SK snRNA methylphosphate capping enzyme O... 116 5e-025
sp|Q9Y7L2|BIN3D_SCHPO Probable methyltransferase C2A9.10 OS=Schi... 112 6e-024
sp|Q7K480|BN3D1_DROME Probable methyltransferase bin3 OS=Drosoph... 87 2e-016
sp|Q9VNH1|BN3D2_DROME Probable methyltransferase CG1239 OS=Droso... 86 4e-016
>sp|Q9U2R0|BIN3D_CAEEL Probable methyltransferase Y17G7B.18 OS=Caenorhabditis
elegans GN=Y17G7B.18 PE=2 SV=1
Length = 378
Score = 193 bits (488), Expect = 3e-048
Identities = 108/303 (35%), Positives = 169/303 (55%), Gaps = 9/303 (2%)
Frame = -1
Query: 1025 DTKTKTKRKRSKEKKSTEKAVTNEEHKQQQQQGNSSSNPSNKKKKKS--QESCPFGNYKN 852
D K++ + S KK+ + + + Q S N+K+K + +GN+
Sbjct: 65 DEKSEKPAENSPFKKNQYNSPRKDSRRPPQLSKEEKSAAENRKQKTEYFNKKYRYGNFDR 124
Query: 851 YYGYRISNDMDEDPRLKVLKKEWFRGKDCLDIGCNSGVMTIHIAKKFGCRSILGVDIDSS 672
YYG R+ N + D RL V +K+WF K LDIGCN+G +T+ IAK F R I+G+DID
Sbjct: 125 YYGIRL-NPGESDKRLSVFQKDWFEHKQALDIGCNAGFLTLSIAKDFSPRRIIGIDIDEH 183
Query: 671 LIEVARWRLRNFVRTQSQGEKKKTGADGSEEQSLSLSNGSSSAAETKELFQVVSFQKENF 492
LI VAR +R++ +++ K + G + ++S N + + TK + F+KEN+
Sbjct: 184 LIGVARKNIRHYCDHETEVSGKFPASFGVQFGTVSQRNEAPRSFSTK-FPDNIWFKKENY 242
Query: 491 V----HSRNLDENRYDTILCLSVTKWVHLNWGDDGLITLFSKIWRLLNPGGISVMEPQPW 324
V ++ + +D IL LS+TKW+HLNWGDDG+ F + + L+PGG ++EPQ +
Sbjct: 243 VLESDEMLDMIQPEFDVILALSITKWIHLNWGDDGMRRFFRRAYAQLHPGGRLIIEPQAF 302
Query: 323 KSYEKNRRVSETTAMNYRNIVLRPEHFQDILLDKIGFRTVEDLTSSLSGASKGFDRQVLA 144
SY+K ++SE NY I +PE F+ L++ +GF +VE L + SKGF+R +
Sbjct: 303 DSYKKRAKMSEELKANYSKIEFKPEDFEMWLIETVGFESVEKL-GVVGAKSKGFERPIDV 361
Query: 143 YQK 135
Y K
Sbjct: 362 YLK 364
>sp|Q7L2J0|MEPCE_HUMAN 7SK snRNA methylphosphate capping enzyme OS=Homo sapiens
GN=MEPCE PE=1 SV=1
Length = 689
Score = 116 bits (290), Expect = 3e-025
Identities = 63/141 (44%), Positives = 82/141 (58%), Gaps = 6/141 (4%)
Frame = -1
Query: 542 AETKELFQVVSFQKENFVHSRN----LDENRYDTILCLSVTKWVHLNWGDDGLITLFSKI 375
A+T V F N+V R+ YD +LCLS+TKWVHLNWGD+GL +F +I
Sbjct: 544 ADTSVFPNNVVFVTGNYVLDRDDLVEAQTPEYDVVLCLSLTKWVHLNWGDEGLKRMFRRI 603
Query: 374 WRLLNPGGISVMEPQPWKSYEKNRRVSETTAMNYRNIVLRPEHFQDILLD-KIGFRTVED 198
+R L PGGI V+EPQPW SY K + ++ET NY I L+PE F L +GF + E
Sbjct: 604 YRHLRPGGILVLEPQPWSSYGKRKTLTETIYKNYYRIQLKPEQFSSYLTSPDVGFSSYE- 662
Query: 197 LTSSLSGASKGFDRQVLAYQK 135
L ++ SKGF R V + K
Sbjct: 663 LVATPHNTSKGFQRPVYLFHK 683
Score = 96 bits (237), Expect = 4e-019
Identities = 52/108 (48%), Positives = 68/108 (62%), Gaps = 6/108 (5%)
Frame = -1
Query: 893 KKSQESCPFGNYKNYYGYRISNDMDEDPRLKVLKKEWFRGKDCLDIGCNSGVMTIHIAKK 714
KK Q +GNY YYGYR N ED RL+VLK EWFRG+D LD+GCN G +T+ IA K
Sbjct: 407 KKQQRKFQYGNYCKYYGYR--NPSCEDGRLRVLKPEWFRGRDVLDLGCNVGHLTLSIACK 464
Query: 713 FGCRSILGVDIDSSLIEVARWRLRNF----VRTQSQGEKKKTGADGSE 582
+G ++G+DIDS LI AR +R++ +R Q + GA+G E
Sbjct: 465 WGPSRMVGLDIDSRLIHSARQNIRHYLSEELRLPPQTLEGDPGAEGEE 512
>sp|Q8K3A9|MEPCE_MOUSE 7SK snRNA methylphosphate capping enzyme OS=Mus musculus
GN=Mepce PE=1 SV=2
Length = 666
Score = 116 bits (288), Expect = 5e-025
Identities = 63/141 (44%), Positives = 86/141 (60%), Gaps = 6/141 (4%)
Frame = -1
Query: 542 AETKELFQVVSFQKENFVHSRN--LDENR--YDTILCLSVTKWVHLNWGDDGLITLFSKI 375
A+T V F N+V R+ +D R YD +LC S+TKWVHLNWGD+GL +F +I
Sbjct: 521 ADTSVFPNNVVFVTGNYVLDRDELVDAQRPEYDVVLCFSLTKWVHLNWGDEGLKRMFRRI 580
Query: 374 WRLLNPGGISVMEPQPWKSYEKNRRVSETTAMNYRNIVLRPEHFQDILLD-KIGFRTVED 198
+R L PGGI V+EPQPW SY K + ++ET NY I L+PE F L ++GF + E
Sbjct: 581 YRHLRPGGILVLEPQPWSSYCKRKSLTETIYKNYFRIQLKPEQFSSYLTSPEVGFSSYE- 639
Query: 197 LTSSLSGASKGFDRQVLAYQK 135
L ++ + S+GF R V + K
Sbjct: 640 LVATPNNTSRGFQRPVYLFHK 660
>sp|Q9Y7L2|BIN3D_SCHPO Probable methyltransferase C2A9.10 OS=Schizosaccharomyces
pombe GN=SPBC2A9.10 PE=2 SV=1
Length = 268
Score = 112 bits (279), Expect = 6e-024
Identities = 74/221 (33%), Positives = 110/221 (49%), Gaps = 13/221 (5%)
Frame = -1
Query: 866 GNYKNYYGYRISNDMDEDPRLKVLKKEWFRGKDCLDIGCNSGVMTIHIAKKFGCRSILGV 687
GNY +YY R + DPRLK L F LDIGCN+G ++ IA FG +LG+
Sbjct: 7 GNYHSYYSMRGGTSI-IDPRLKCLPDSLFYEASVLDIGCNNGTVSAQIASIFGASFVLGL 65
Query: 686 DIDSSLIEVARWRLRNFVRTQSQGEKKKTGADGSEEQSLSLSNGSSSAAETKELFQVVSF 507
DID LI+ AR L FV ++ G + G+ ++ + + + Q
Sbjct: 66 DIDHVLIQKARKHL-EFVSSRI-GPVRNPGSIVEDQFNYYPISSIKKFSRIPVQLQ-PPL 122
Query: 506 QKENFVHSRNLD---------ENRYDTILCLSVTKWVHLNWGDDGLITLFSKIWRLLNPG 354
K+NF H+ + + ++ IL LSV+KWVHLN D+G+I F KI LL
Sbjct: 123 NKQNFPHNIEFETADFLRWESKRKFKIILALSVSKWVHLNNHDEGIIKFFGKISSLLETN 182
Query: 353 GISVMEPQPWKSYEKNRRVSETTAMNYRNIVLRPEHFQDIL 231
G+ ++EPQ W SY K + N+ ++P+ F+ +L
Sbjct: 183 GVLILEPQGWDSYLKAAKKISVFNQTPENLKIQPDAFEHLL 223
>sp|Q7K480|BN3D1_DROME Probable methyltransferase bin3 OS=Drosophila
melanogaster GN=bin3 PE=1 SV=1
Length = 1367
Score = 87 bits (214), Expect = 2e-016
Identities = 46/114 (40%), Positives = 65/114 (57%), Gaps = 2/114 (1%)
Frame = -1
Query: 473 DENRYDTILCLSVTKWVHLNWGDDGLITLFSKIWRLLNPGGISVMEPQPWKSYEKNRRVS 294
D +YD ILCLSVTKW+HLN+GD+GL F +++ L PGG ++E Q W SY+K + ++
Sbjct: 1000 DTQQYDLILCLSVTKWIHLNFGDNGLKMAFKRMFNQLRPGGKLILEAQNWASYKKKKNLT 1059
Query: 293 ETTAMNYRNIVLRPEHFQDILL-DKIGFRTVEDLTSSLSGASKGFDRQVLAYQK 135
NY+ I P F + LL ++GF L +KGF R + Y K
Sbjct: 1060 PEIYNNYKQIEFFPNKFHEYLLSSEVGFSHSYTL-GVPRHMNKGFCRPIQLYAK 1112
Score = 68 bits (164), Expect = 1e-010
Identities = 41/117 (35%), Positives = 67/117 (57%), Gaps = 5/117 (4%)
Frame = -1
Query: 869 FGNYKNYYGYRISNDMDEDPRLKVLKK--EWFRGKDCLDIGCNSGVMTIHIAKKFGCRSI 696
+GN+ Y +R N+ D RL+V ++ E F KD LDIGCN G MTI +A+ ++I
Sbjct: 789 YGNFDRYVDFRQMNEF-RDVRLQVFQRHVELFENKDILDIGCNVGHMTITVARHLAPKTI 847
Query: 695 LGVDIDSSLIEVARWRLRNFVRTQSQGEKKKTGADGS--EEQSLSLSNGSSSAAETK 531
+G+DID L+ AR L FVR + + + A+ + + ++++ + +S AA K
Sbjct: 848 VGIDIDRELVARARRNLSIFVRIPKEEKLLEVKAEPTVDAKANIAVKDETSGAAHKK 904
>sp|Q9VNH1|BN3D2_DROME Probable methyltransferase CG1239 OS=Drosophila
melanogaster GN=CG1239 PE=2 SV=2
Length = 300
Score = 86 bits (212), Expect = 4e-016
Identities = 43/115 (37%), Positives = 68/115 (59%), Gaps = 2/115 (1%)
Frame = -1
Query: 476 LDENRYDTILCLSVTKWVHLNWGDDGLITLFSKIWRLLNPGGISVMEPQPWKSYEKNRRV 297
++ ++D ILCLSVTKW+HLN+ D GL F +++ L PGG ++EPQ + Y++ +++
Sbjct: 186 IERPQFDVILCLSVTKWIHLNFCDSGLKQAFRRMYLQLRPGGKLILEPQSFDGYKRRKKL 245
Query: 296 SETTAMNYRNIVLRPEHFQDILLD-KIGFRTVEDLTSSLSGASKGFDRQVLAYQK 135
SE NY I RP+HF + LL ++GF ++ L GF R + + K
Sbjct: 246 SEQIRDNYNAIKFRPDHFTEYLLSPEVGFAEMK-LMGIPEHCKVGFKRPIQIFTK 299
Score = 81 bits (198), Expect = 1e-014
Identities = 48/136 (35%), Positives = 78/136 (57%), Gaps = 6/136 (4%)
Frame = -1
Query: 1013 KTKRKRSKEKKSTEKAVTNEEHKQQQQQGNSSSNPSNKKKKKSQESCPFGNYKNYYGYRI 834
+ + KR K+++S +A + + +++ + + P K + +GNYK+YYG RI
Sbjct: 33 QVESKRLKKEESNVEATSRPPAQSPKKRLHLNGKPMQNKDLNFK----YGNYKHYYGKRI 88
Query: 833 SNDMDEDPRLKVL--KKEWFRGKDCLDIGCNSGVMTIHIAKKFGCRSILGVDIDSSLIEV 660
N D RL VL + + FR K LDIGCNSG ++I IA+KF +S++G+DID LI
Sbjct: 89 LNKDFHDIRLDVLGTQPDLFRNKQLLDIGCNSGHLSIQIARKFEVKSLVGLDIDRGLIND 148
Query: 659 ARWRLRNFVRTQSQGE 612
A+ + + R + G+
Sbjct: 149 AQKTVSHLKRHATPGQ 164
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 129,408,327,353
Number of Sequences: 518415
Number of Extensions: 129408327353
Number of Successful Extensions: 804511681
Number of sequences better than 0.0: 0
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