BLASTX 7.6.2
Query= UN33187 /QuerySize=1130
(1129 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O16102|CHD3_DROME Chromodomain-helicase-DNA-binding protein 3... 86 6e-016
sp|O97159|CHDM_DROME Chromodomain-helicase-DNA-binding protein M... 78 1e-013
sp|Q14839|CHD4_HUMAN Chromodomain-helicase-DNA-binding protein 4... 75 6e-013
sp|Q6PDQ2|CHD4_MOUSE Chromodomain-helicase-DNA-binding protein 4... 75 6e-013
sp|Q8TDI0|CHD5_HUMAN Chromodomain-helicase-DNA-binding protein 5... 75 6e-013
sp|Q12873|CHD3_HUMAN Chromodomain-helicase-DNA-binding protein 3... 72 5e-012
sp|Q56R14|TRI33_XENLA E3 ubiquitin-protein ligase TRIM33 OS=Xeno... 69 4e-011
sp|Q64127|TIF1A_MOUSE Transcription intermediary factor 1-alpha ... 69 5e-011
sp|O15164|TIF1A_HUMAN Transcription intermediary factor 1-alpha ... 69 7e-011
sp|Q96BD5|PF21A_HUMAN PHD finger protein 21A OS=Homo sapiens GN=... 68 9e-011
sp|Q6ZPK0|PF21A_MOUSE PHD finger protein 21A OS=Mus musculus GN=... 68 9e-011
sp|Q9UPN9|TRI33_HUMAN E3 ubiquitin-protein ligase TRIM33 OS=Homo... 68 1e-010
sp|Q99PP7|TRI33_MOUSE E3 ubiquitin-protein ligase TRIM33 OS=Mus ... 68 1e-010
sp|Q924W6|TRI66_MOUSE Tripartite motif-containing protein 66 OS=... 64 1e-009
sp|Q96EK2|PF21B_HUMAN PHD finger protein 21B OS=Homo sapiens GN=... 64 2e-009
sp|Q6E2N3|TRI33_DANRE E3 ubiquitin-protein ligase TRIM33 OS=Dani... 64 2e-009
sp|O15016|TRI66_HUMAN Tripartite motif-containing protein 66 OS=... 62 9e-009
sp|Q80Y84|KDM5B_MOUSE Lysine-specific demethylase 5B OS=Mus musc... 60 2e-008
sp|Q8C966|PF21B_MOUSE PHD finger protein 21B OS=Mus musculus GN=... 60 2e-008
sp|Q30DN6|KDM5D_CANFA Lysine-specific demethylase 5D OS=Canis fa... 58 1e-007
>sp|O16102|CHD3_DROME Chromodomain-helicase-DNA-binding protein 3 OS=Drosophila
melanogaster GN=Chd3 PE=2 SV=3
Length = 892
Score = 86 bits (210), Expect = 6e-016
Identities = 37/69 (53%), Positives = 44/69 (63%), Gaps = 2/69 (2%)
Frame = -3
Query: 545 TNHQPSIDVTPQGTSSKRKGHDGNYFECVICDLGGDLLCCDSCPRTYHTACLTPPLKRIP 366
T + S D P+ + K+K D Y C +C GGDLLCCDSCP YH CL+PPLK IP
Sbjct: 13 TPGKASKDKRPKTNAKKQKFRDEEY--CKVCSDGGDLLCCDSCPSVYHRTCLSPPLKSIP 70
Query: 365 NGKWICPKC 339
G WICP+C
Sbjct: 71 KGDWICPRC 79
>sp|O97159|CHDM_DROME Chromodomain-helicase-DNA-binding protein Mi-2 homolog
OS=Drosophila melanogaster GN=Mi-2 PE=1 SV=2
Length = 1982
Score = 78 bits (190), Expect = 1e-013
Identities = 40/117 (34%), Positives = 60/117 (51%), Gaps = 18/117 (15%)
Frame = -3
Query: 536 QPSIDVTPQGT-----------SSKRKGHDGNYFECVICDLGGDLLCCDSCPRTYHTACL 390
+P +D P+G +++ + D + C +C GG+LLCCDSCP YHT CL
Sbjct: 405 EPELDEPPEGKWSCPHCEADGGAAEEEDDDEHQEFCRVCKDGGELLCCDSCPSAYHTFCL 464
Query: 389 TPPLKRIPNGKWICPKCSQDRSALKPTTRLDAISKRARTKTSKRNSQDRPKSERASQ 219
PPL IP+G W CP+CS P T K + ++R++ D P + + S+
Sbjct: 465 NPPLDTIPDGDWRCPRCS-----CPPLT--GKAEKIITWRWAQRSNDDGPSTSKGSK 514
>sp|Q14839|CHD4_HUMAN Chromodomain-helicase-DNA-binding protein 4 OS=Homo
sapiens GN=CHD4 PE=1 SV=1
Length = 1912
Score = 75 bits (184), Expect = 6e-013
Identities = 28/50 (56%), Positives = 38/50 (76%), Gaps = 1/50 (2%)
Frame = -3
Query: 482 DGNYFE-CVICDLGGDLLCCDSCPRTYHTACLTPPLKRIPNGKWICPKCS 336
D ++ E C +C GG+LLCCD+CP +YH CL PPL IPNG+W+CP+C+
Sbjct: 445 DDHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLCPRCT 494
>sp|Q6PDQ2|CHD4_MOUSE Chromodomain-helicase-DNA-binding protein 4 OS=Mus
musculus GN=Chd4 PE=1 SV=1
Length = 1915
Score = 75 bits (184), Expect = 6e-013
Identities = 28/50 (56%), Positives = 38/50 (76%), Gaps = 1/50 (2%)
Frame = -3
Query: 482 DGNYFE-CVICDLGGDLLCCDSCPRTYHTACLTPPLKRIPNGKWICPKCS 336
D ++ E C +C GG+LLCCD+CP +YH CL PPL IPNG+W+CP+C+
Sbjct: 438 DDHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLCPRCT 487
>sp|Q8TDI0|CHD5_HUMAN Chromodomain-helicase-DNA-binding protein 5 OS=Homo
sapiens GN=CHD5 PE=1 SV=1
Length = 1954
Score = 75 bits (184), Expect = 6e-013
Identities = 29/67 (43%), Positives = 41/67 (61%)
Frame = -3
Query: 536 QPSIDVTPQGTSSKRKGHDGNYFECVICDLGGDLLCCDSCPRTYHTACLTPPLKRIPNGK 357
+P D + + D + C +C GG+LLCCD+CP +YH CL PPL IPNG+
Sbjct: 395 EPKDDDDEEEEGGCEEEEDDHMEFCRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGE 454
Query: 356 WICPKCS 336
W+CP+C+
Sbjct: 455 WLCPRCT 461
>sp|Q12873|CHD3_HUMAN Chromodomain-helicase-DNA-binding protein 3 OS=Homo
sapiens GN=CHD3 PE=1 SV=3
Length = 2000
Score = 72 bits (176), Expect = 5e-012
Identities = 28/60 (46%), Positives = 40/60 (66%), Gaps = 1/60 (1%)
Frame = -3
Query: 512 QGTSSKRKGHDGNYFE-CVICDLGGDLLCCDSCPRTYHTACLTPPLKRIPNGKWICPKCS 336
+G K + ++ E C +C GG+LLCCD+C +YH CL PPL IPNG+W+CP+C+
Sbjct: 442 EGEEEGEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRCT 501
>sp|Q56R14|TRI33_XENLA E3 ubiquitin-protein ligase TRIM33 OS=Xenopus laevis
GN=trim33 PE=1 SV=1
Length = 1091
Score = 69 bits (168), Expect = 4e-011
Identities = 53/189 (28%), Positives = 84/189 (44%), Gaps = 18/189 (9%)
Frame = -3
Query: 731 QKGDTSAAIIDSPDCTSSDKPTKH-----QLKAGSAPERTSKRKGQSLAEN--NSLAVGS 573
+ G SA ++ SP+ + + T + L++ +A E K + + +++ S V
Sbjct: 759 EDGRRSACMLSSPESSLTPPLTTNVHLETDLESLAALENNVKTEPNNTSQSCRQSSHVSL 818
Query: 572 PEFTSSEKLTNHQPSIDVTPQGTSSKRKGHDGNYFECVICDLGGDLLCCDSCPRTYHTAC 393
S+ + + H+P G K D N C +C GGDLLCC+ CP+ +H C
Sbjct: 819 VNGKSAVRNSMHRPPRG--GGGGDGSNKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTC 876
Query: 392 LTPPLKRIPNGKWICPKCSQDRSALKPTTRLDA----ISKRARTKTSKRNSQDRPKSER- 228
P L P+G+WIC C R KP D SK+ +T + D+ K ER
Sbjct: 877 HVPTLLSFPSGEWICTFC---RDLNKPEVEYDCDNSQHSKKGKT-VQGLSPVDQMKCERL 932
Query: 227 ASQIYCSSI 201
+YC +
Sbjct: 933 LLYLYCHEL 941
>sp|Q64127|TIF1A_MOUSE Transcription intermediary factor 1-alpha OS=Mus musculus
GN=Trim24 PE=1 SV=1
Length = 1051
Score = 69 bits (167), Expect = 5e-011
Identities = 38/110 (34%), Positives = 49/110 (44%), Gaps = 10/110 (9%)
Frame = -3
Query: 518 TPQGTSSKRKGHDGNYFECVICDLGGDLLCCDSCPRTYHTACLTPPLKRIPNGKWICPKC 339
+P RK D N C +C GG+LLCC+ CP+ +H C P L P+G+WIC C
Sbjct: 812 SPVHVGETRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLTCHVPTLTNFPSGEWICTFC 871
Query: 338 SQDRSALKPTTRLDA------ISKRARTKTSKRNSQDRPKSERASQ-IYC 210
R KP D KR +K D+ K ER +YC
Sbjct: 872 ---RDLSKPEVDYDCDVPSHHSEKRKSEGLTKLTPIDKRKCERLLLFLYC 918
>sp|O15164|TIF1A_HUMAN Transcription intermediary factor 1-alpha OS=Homo sapiens
GN=TRIM24 PE=1 SV=3
Length = 1050
Score = 69 bits (166), Expect = 7e-011
Identities = 38/108 (35%), Positives = 53/108 (49%), Gaps = 6/108 (5%)
Frame = -3
Query: 518 TPQGTSSKRKGHDGNYFECVICDLGGDLLCCDSCPRTYHTACLTPPLKRIPNGKWICPKC 339
+P RK D N C +C GG+LLCC+ CP+ +H +C P L P+G+WIC C
Sbjct: 811 SPLHVGETRKEDDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFC 870
Query: 338 SQDRSALKPTTRLDAISKRARTKTS----KRNSQDRPKSERASQ-IYC 210
+D S + DA S + K + K D+ K ER +YC
Sbjct: 871 -RDLSKPEVEYDCDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYC 917
>sp|Q96BD5|PF21A_HUMAN PHD finger protein 21A OS=Homo sapiens GN=PHF21A PE=1
SV=1
Length = 680
Score = 68 bits (165), Expect = 9e-011
Identities = 31/58 (53%), Positives = 36/58 (62%), Gaps = 3/58 (5%)
Frame = -3
Query: 482 DGNYFE--CVICDLGGDLLCCDSCPRTYHTACLTPPLKRIPNGKWICPKCSQDRSALK 315
DG+ E C +C G LL CD+C R YH CL PPLK IP G WICP+C QD+ K
Sbjct: 483 DGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLDPPLKTIPKGMWICPRC-QDQMLKK 539
>sp|Q6ZPK0|PF21A_MOUSE PHD finger protein 21A OS=Mus musculus GN=Phf21a PE=1
SV=2
Length = 659
Score = 68 bits (165), Expect = 9e-011
Identities = 31/58 (53%), Positives = 36/58 (62%), Gaps = 3/58 (5%)
Frame = -3
Query: 482 DGNYFE--CVICDLGGDLLCCDSCPRTYHTACLTPPLKRIPNGKWICPKCSQDRSALK 315
DG+ E C +C G LL CD+C R YH CL PPLK IP G WICP+C QD+ K
Sbjct: 463 DGDIHEDFCSVCRKSGQLLMCDTCSRVYHLDCLEPPLKTIPKGMWICPRC-QDQMLKK 519
>sp|Q9UPN9|TRI33_HUMAN E3 ubiquitin-protein ligase TRIM33 OS=Homo sapiens
GN=TRIM33 PE=1 SV=2
Length = 1127
Score = 68 bits (164), Expect = 1e-010
Identities = 38/107 (35%), Positives = 50/107 (46%), Gaps = 7/107 (6%)
Frame = -3
Query: 509 GTSSKRKGHDGNYFECVICDLGGDLLCCDSCPRTYHTACLTPPLKRIPNGKWICPKCSQD 330
G K D N C +C GGDLLCC+ CP+ +H C P L P+G WIC C
Sbjct: 875 GGDGNNKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFC--- 931
Query: 329 RSALKPTTRLDA--ISKRARTKTSKRNSQ-DRPKSER-ASQIYCSSI 201
R KP D + + KT++ S D+ K ER +YC +
Sbjct: 932 RDIGKPEVEYDCDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHEL 978
>sp|Q99PP7|TRI33_MOUSE E3 ubiquitin-protein ligase TRIM33 OS=Mus musculus
GN=Trim33 PE=2 SV=2
Length = 1142
Score = 68 bits (164), Expect = 1e-010
Identities = 47/185 (25%), Positives = 71/185 (38%), Gaps = 12/185 (6%)
Frame = -3
Query: 731 QKGDTSAAIIDSPDCTSSDKPTKHQLKAGSAPERTSKRKGQSLAENNSLAVGSPEFTSSE 552
+ G SA ++ SP+ +S P L S + + + E ++ + S
Sbjct: 813 EDGRRSACMLSSPE-SSLTPPLSTNLHLESELDTLTGLENHVKTEPTDISESCKQSGLSN 871
Query: 551 KLTNHQPSIDVTPQ----GTSSKRKGHDGNYFECVICDLGGDLLCCDSCPRTYHTACLTP 384
+ P ++ + G K D N C +C GGDLLCC+ CP+ +H C P
Sbjct: 872 LVNGKSPIRNLMHRSARIGGDGNSKDDDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVP 931
Query: 383 PLKRIPNGKWICPKCSQDRSALKPTTRLDA----ISKRARTKTSKRNSQDRPKSERASQI 216
L P+G WIC C R KP D SK+ +T R +
Sbjct: 932 TLLSFPSGDWICTFC---RDIGKPEVEYDCDNMQHSKKGKTAQGLSPVDQRKCERLLLYL 988
Query: 215 YCSSI 201
YC +
Sbjct: 989 YCHEL 993
>sp|Q924W6|TRI66_MOUSE Tripartite motif-containing protein 66 OS=Mus musculus
GN=Trim66 PE=1 SV=2
Length = 1242
Score = 64 bits (155), Expect = 1e-009
Identities = 26/61 (42%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Frame = -3
Query: 464 CVICDLGGDLLCCDSCPRTYHTACLTPPLKRIPNGKWICPKCSQDRSALKPTTRLDAISK 285
C +C GG+LLCCD CP+ YH +C P L P G+W+C C RS +P D +
Sbjct: 999 CAVCINGGELLCCDRCPKVYHLSCHVPALLSFPGGEWVCTLC---RSLTQPEMEYDCENA 1055
Query: 284 R 282
R
Sbjct: 1056 R 1056
>sp|Q96EK2|PF21B_HUMAN PHD finger protein 21B OS=Homo sapiens GN=PHF21B PE=2
SV=1
Length = 531
Score = 64 bits (153), Expect = 2e-009
Identities = 32/88 (36%), Positives = 45/88 (51%), Gaps = 7/88 (7%)
Frame = -3
Query: 464 CVICDLGGDLLCCDSCPRTYHTACLTPPLKRIPNGKWICPKCSQDRSALK-----PTTRL 300
C C G +L C +CP YH +CL PPLK P G W+CP+C Q ALK P T +
Sbjct: 355 CAACKRGANLQPCGTCPGAYHLSCLEPPLKTAPKGVWVCPRCQQ--KALKKDEGVPWTGM 412
Query: 299 DAISKRARTKTSKRNSQDRPKSERASQI 216
AI T + + + + +R S++
Sbjct: 413 LAIVHSYVTHKTVKEEEKQKLLQRGSEL 440
>sp|Q6E2N3|TRI33_DANRE E3 ubiquitin-protein ligase TRIM33 OS=Danio rerio
GN=trim33 PE=2 SV=1
Length = 1163
Score = 64 bits (153), Expect = 2e-009
Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 3/92 (3%)
Frame = -3
Query: 491 KGHDGNYFECVICDLGGDLLCCDSCPRTYHTACLTPPLKRIPNGKWICPKCSQDRSALKP 312
K D N C +C GG+LLCCD CP+ +H C P LK P+G W+C C R+ P
Sbjct: 915 KEDDPNEDWCAVCQNGGELLCCDHCPKVFHITCHIPTLKSSPSGDWMCTFC---RNLANP 971
Query: 311 TTRLDAISKRARTKTSKRNSQDRPKSERASQI 216
+ R K + + R ++
Sbjct: 972 EIEYNCDDDPPRNKEKNEMAMSPEEQRRCERL 1003
>sp|O15016|TRI66_HUMAN Tripartite motif-containing protein 66 OS=Homo sapiens
GN=TRIM66 PE=2 SV=4
Length = 1216
Score = 62 bits (148), Expect = 9e-009
Identities = 24/56 (42%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Frame = -3
Query: 464 CVICDLGGDLLCCDSCPRTYHTACLTPPLKRIPNGKWICPKCSQDRSALKPTTRLD 297
C +C GG+LLCCD CP+ +H +C P L P G+W+C C RS +P D
Sbjct: 973 CAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLC---RSLTQPEMEYD 1025
>sp|Q80Y84|KDM5B_MOUSE Lysine-specific demethylase 5B OS=Mus musculus GN=Kdm5b
PE=1 SV=1
Length = 1544
Score = 60 bits (145), Expect = 2e-008
Identities = 24/47 (51%), Positives = 29/47 (61%), Gaps = 3/47 (6%)
Frame = -3
Query: 470 FECVICDLGGD---LLCCDSCPRTYHTACLTPPLKRIPNGKWICPKC 339
+ C++C G D LL CD C +YHT CL PPL +P G W CPKC
Sbjct: 310 YVCLLCGSGNDEDRLLLCDGCDDSYHTFCLVPPLHDVPKGDWRCPKC 356
>sp|Q8C966|PF21B_MOUSE PHD finger protein 21B OS=Mus musculus GN=Phf21b PE=2
SV=1
Length = 487
Score = 60 bits (145), Expect = 2e-008
Identities = 32/88 (36%), Positives = 43/88 (48%), Gaps = 7/88 (7%)
Frame = -3
Query: 464 CVICDLGGDLLCCDSCPRTYHTACLTPPLKRIPNGKWICPKCSQDRSALK-----PTTRL 300
C C G L C +C YH +CL PPLK P G W+CPKC R ALK P T +
Sbjct: 310 CAACKRGASLQPCGTCSGAYHLSCLDPPLKTPPKGLWVCPKC--QRKALKKDEGVPWTGM 367
Query: 299 DAISKRARTKTSKRNSQDRPKSERASQI 216
AI T + + + + +R S++
Sbjct: 368 LAIVHSYVTHKTVKEEEKQKLLQRGSEL 395
>sp|Q30DN6|KDM5D_CANFA Lysine-specific demethylase 5D OS=Canis familiaris
GN=KDM5D PE=2 SV=1
Length = 1545
Score = 58 bits (138), Expect = 1e-007
Identities = 25/47 (53%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Frame = -3
Query: 470 FECVICDLGGD---LLCCDSCPRTYHTACLTPPLKRIPNGKWICPKC 339
+ C IC G + LL CD C TYH CL PPL IP G W CPKC
Sbjct: 318 YVCRICSRGDEDDKLLLCDGCDDTYHIFCLIPPLPEIPRGVWRCPKC 364
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 132,248,888,565
Number of Sequences: 518415
Number of Extensions: 132248888565
Number of Successful Extensions: 812634680
Number of sequences better than 0.0: 0
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