BLASTX 7.6.2
Query= UN33470 /QuerySize=891
(890 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q7S2H8|TPC1_NEUCR Mitochondrial thiamine pyrophosphate carrie... 83 3e-015
sp|Q8BGF9|S2544_MOUSE Solute carrier family 25 member 44 OS=Mus ... 82 6e-015
sp|Q5RD67|S2544_PONAB Solute carrier family 25 member 44 OS=Pong... 77 2e-013
sp|Q96H78|S2544_HUMAN Solute carrier family 25 member 44 OS=Homo... 75 5e-013
sp|Q1DRJ3|S2538_COCIM Solute carrier family 25 member 38 homolog... 72 4e-012
sp|Q9P6N6|S2538_SCHPO Solute carrier family 25 member 38 homolog... 66 3e-010
sp|Q55E45|MCFE_DICDI Mitochondrial substrate carrier family prot... 62 5e-009
sp|P10566|MRS3_YEAST Mitochondrial RNA-splicing protein MRS3 OS=... 55 4e-007
sp|P23500|MRS4_YEAST Mitochondrial RNA-splicing protein MRS4 OS=... 55 4e-007
sp|A2R5A0|TPC1_ASPNC Mitochondrial thiamine pyrophosphate carrie... 54 1e-006
sp|Q59Q36|TPC1_CANAL Mitochondrial thiamine pyrophosphate carrie... 52 6e-006
>sp|Q7S2H8|TPC1_NEUCR Mitochondrial thiamine pyrophosphate carrier 1
OS=Neurospora crassa GN=tpc-1 PE=3 SV=1
Length = 333
Score = 83 bits (203), Expect = 3e-015
Identities = 58/208 (27%), Positives = 96/208 (46%), Gaps = 23/208 (11%)
Frame = +2
Query: 26 AGMTASLFSQAVFVPIDVVSQKLMVQGYS---------------GHATYTGGIDVATKII 160
AG TA L S+ V P+DVV +L +Q +S G Y G + I+
Sbjct: 20 AGATAGLISRFVIAPLDVVKIRLQLQHHSLSDPLLHQRRAEIIGGGPVYKGTLPTIRHIL 79
Query: 161 KSYGVRGLYRGFGLSVMTYSPSSAAWWASYGSSQRVIWRLLGYGSDSEATVAPSQSKIVL 340
++ G+ GL++G + + Y +A + +Y S + + + D + PS +
Sbjct: 80 RTEGLTGLWKGNIPAELLYVSYAAVQFTTYRSITQFL--QAAFPKDQNKQLPPSVESFI- 136
Query: 341 VQALGGIIAGATASSITTPLDTIKTRLQVMGHQENRPSAKQVVKDLIAQDGWKGFYRGLG 520
G AG A+++T PLD ++TR G + PS Q +K + A +G G++RGLG
Sbjct: 137 ----AGASAGGVATAVTYPLDLLRTRFAAQGVERVYPSLVQALKTIYASEGVTGYFRGLG 192
Query: 521 PRFFSMSAWGTSMILTYEYLK-RLCAIE 601
P + + + YE L+ RL +E
Sbjct: 193 PGLAQIIPYMGTFFCVYETLRPRLSKLE 220
>sp|Q8BGF9|S2544_MOUSE Solute carrier family 25 member 44 OS=Mus musculus
GN=Slc25a44 PE=2 SV=1
Length = 314
Score = 82 bits (200), Expect = 6e-015
Identities = 61/196 (31%), Positives = 99/196 (50%), Gaps = 14/196 (7%)
Frame = +2
Query: 23 MAGMTASLFSQAVFVPIDVVSQKLMVQ-------GYSGHATYTGGIDVATKIIKSYGVRG 181
+AG +ASL +Q++ VPIDVVSQ LM+Q + H G +A K +R
Sbjct: 114 VAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVHGNLEGQGVIAFGQTKDI-IRQ 172
Query: 182 LYRGFGLSVMTYSPSSAAWWASYGSSQRVIWRLLGYGSDSEATVAPSQSKIVLVQALGGI 361
+ R GL + A +Y + V W + ++ + + P + ++ QA+ G
Sbjct: 173 ILRADGL--RGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSRLCPQECPHIVFQAISGP 230
Query: 362 IAGATASSITTPLDTIKTRLQVMGHQENRPSAKQVVKDLIAQDGWKGFYRGLGPRFFSMS 541
+A ATAS +T P+D I+TR+QV E + S + L+A++G G +GL R S +
Sbjct: 231 LAAATASILTNPMDVIRTRVQV----EGKSSIVLTFRQLMAEEGPWGLMKGLSARIISAT 286
Query: 542 AWGTSMILTYEYLKRL 589
+++ YE LK+L
Sbjct: 287 PSTIVIVVGYESLKKL 302
>sp|Q5RD67|S2544_PONAB Solute carrier family 25 member 44 OS=Pongo abelii
GN=SLC25A44 PE=2 SV=2
Length = 314
Score = 77 bits (187), Expect = 2e-013
Identities = 61/196 (31%), Positives = 98/196 (50%), Gaps = 14/196 (7%)
Frame = +2
Query: 23 MAGMTASLFSQAVFVPIDVVSQKLMVQ-------GYSGHATYTGGIDVATKIIKSYGVRG 181
+AG +ASL +Q++ VPIDVVSQ LM+Q + G VA K +R
Sbjct: 114 VAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDI-IRQ 172
Query: 182 LYRGFGLSVMTYSPSSAAWWASYGSSQRVIWRLLGYGSDSEATVAPSQSKIVLVQALGGI 361
+ R GL + A +Y + V W + ++ + + P + ++ QA+ G
Sbjct: 173 ILRADGL--RGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGP 230
Query: 362 IAGATASSITTPLDTIKTRLQVMGHQENRPSAKQVVKDLIAQDGWKGFYRGLGPRFFSMS 541
+A ATAS +T P+D I+TR+QV E + S + L+A++G G +GL R S +
Sbjct: 231 LAAATASILTNPMDVIRTRVQV----EGKNSIILTFRQLMAEEGPWGLMKGLSARIISAT 286
Query: 542 AWGTSMILTYEYLKRL 589
+++ YE LK+L
Sbjct: 287 PSTIVIVVGYESLKKL 302
>sp|Q96H78|S2544_HUMAN Solute carrier family 25 member 44 OS=Homo sapiens
GN=SLC25A44 PE=2 SV=1
Length = 314
Score = 75 bits (183), Expect = 5e-013
Identities = 60/196 (30%), Positives = 98/196 (50%), Gaps = 14/196 (7%)
Frame = +2
Query: 23 MAGMTASLFSQAVFVPIDVVSQKLMVQ-------GYSGHATYTGGIDVATKIIKSYGVRG 181
+AG +ASL +Q++ VPIDVVSQ LM+Q + G VA K +R
Sbjct: 114 VAGGSASLVAQSITVPIDVVSQHLMMQRKGEKMGRFQVRGNPEGQGVVAFGQTKDI-IRQ 172
Query: 182 LYRGFGLSVMTYSPSSAAWWASYGSSQRVIWRLLGYGSDSEATVAPSQSKIVLVQALGGI 361
+ + GL + A +Y + V W + ++ + + P + ++ QA+ G
Sbjct: 173 ILQADGL--RGFYRGYVASLLTYIPNSAVWWPFYHFYAEQLSYLCPKECPHIVFQAVSGP 230
Query: 362 IAGATASSITTPLDTIKTRLQVMGHQENRPSAKQVVKDLIAQDGWKGFYRGLGPRFFSMS 541
+A ATAS +T P+D I+TR+QV E + S + L+A++G G +GL R S +
Sbjct: 231 LAAATASILTNPMDVIRTRVQV----EGKNSIILTFRQLMAEEGPWGLMKGLSARIISAT 286
Query: 542 AWGTSMILTYEYLKRL 589
+++ YE LK+L
Sbjct: 287 PSTIVIVVGYESLKKL 302
>sp|Q1DRJ3|S2538_COCIM Solute carrier family 25 member 38 homolog
OS=Coccidioides immitis GN=CIMG_07070 PE=3 SV=1
Length = 347
Score = 72 bits (176), Expect = 4e-012
Identities = 50/175 (28%), Positives = 83/175 (47%), Gaps = 10/175 (5%)
Frame = +2
Query: 14 ANGMAGMTASLFSQAVFVPIDVVSQKLMVQGYSGHATYTGGIDVATKIIKSYGVRGLYRG 193
AN + G A + + V +P+ V L V+ S + Y A I++ GVRGL+ G
Sbjct: 142 ANLITGAVARVAAGFVMMPVTV----LKVRYESDYYAYRSLWGAAKDIVRHEGVRGLFAG 197
Query: 194 FGLSVMTYSPSSAAWWASYGSSQRVIWRLLGYGSDSEATVAPSQSK----IVLVQALGGI 361
FG + + +P + + Y S+R + LLG S S + Q K + + G
Sbjct: 198 FGATAIRDAPYAGLYVVFYEQSKRSLASLLGASSPSARSTPTEQQKSPPSTASINFISGA 257
Query: 362 IAGATASSITTPLDTIKTRLQVMGHQENRPSAKQVVKDLIAQDGWKGFYRGLGPR 526
+A A++IT P D +KTR+Q+M + + ++ +DG + + GLG R
Sbjct: 258 LAAGLATTITNPFDVVKTRVQLM--PSKYKNMMRATALMLREDGMRSLFGGLGLR 310
>sp|Q9P6N6|S2538_SCHPO Solute carrier family 25 member 38 homolog
OS=Schizosaccharomyces pombe GN=SPAC823.10c PE=2 SV=1
Length = 296
Score = 66 bits (160), Expect = 3e-010
Identities = 52/174 (29%), Positives = 86/174 (49%), Gaps = 11/174 (6%)
Frame = +2
Query: 62 FVPIDVVSQKLMVQGYSGHATYTGGIDVATKIIKSYGVRGLYRGFGLSVMTYSPSSAAWW 241
F+P+ V+ + YS Y+ D I K G+ G +RGFG++ + +P + +
Sbjct: 124 FMPVTVIKVRYESNLYSYTTIYSSIRD----IWKKEGISGFFRGFGVTALRDAPHAGLYV 179
Query: 242 ASYGSSQRVIWRLLGYGSDSEATVAPSQSKIVLVQALGGIIAGATASSITTPLDTIKTRL 421
Y S++ + +L S S ++V + +V + G+I+GATA++IT P D +KTR+
Sbjct: 180 YFYELSKQNLHKLFDRFSPS-SSVQGTVPHRNIVNVMSGLISGATATAITNPFDMLKTRV 238
Query: 422 QVMGH--QENRPSAKQVVKDLIAQDGWKGFYRGLGPRFFSMSAWGTSMILTYEY 577
Q+ H + SAK V A +G++GF G R S T YE+
Sbjct: 239 QLEPHIYKNFLHSAKLV----YANEGFRGFLDGFFLRVLRKSISSTITWSVYEW 288
>sp|Q55E45|MCFE_DICDI Mitochondrial substrate carrier family protein E
OS=Dictyostelium discoideum GN=mcfE PE=3 SV=1
Length = 303
Score = 62 bits (149), Expect = 5e-009
Identities = 45/191 (23%), Positives = 79/191 (41%), Gaps = 11/191 (5%)
Frame = +2
Query: 26 AGMTASLFSQAVFVPIDVVSQKLMVQGYS-----GHATYTGGIDVATKIIKSYGVRGLYR 190
AG A ++VP+D++ Q+L VQ + Y G I++ G+RGLYR
Sbjct: 112 AGFVADALGSLIWVPMDIIKQRLQVQTNTQKLNPNQTYYKGSFHAGKIILQEEGIRGLYR 171
Query: 191 GFGLSVMTYSPSSAAWWASYGSSQRVIWRLLGYGSDSEATVAPSQSKIVLVQALGGIIAG 370
GF ++ TY P +++ Y + I LL D + A
Sbjct: 172 GFMPALATYGPFVGIYFSVYEKCKSTISSLLSKEKDQYLPIPYQLGSGFFAGAF------ 225
Query: 371 ATASSITTPLDTIKTRLQVMGHQENRPSAKQVVKDLIAQDGWKGFYRGLGPRFFSMSAWG 550
A A + + + ++Q ++ K ++ ++G K F +G+G R + ++
Sbjct: 226 AAAVTCPLDVIKTRIQVQRSTEKQIYKGMWDSFKTILKEEGPKAFVKGMGARIWWIAPGN 285
Query: 551 TSMILTYEYLK 583
I +YE LK
Sbjct: 286 ALTIASYEQLK 296
>sp|P10566|MRS3_YEAST Mitochondrial RNA-splicing protein MRS3 OS=Saccharomyces
cerevisiae GN=MRS3 PE=1 SV=4
Length = 314
Score = 55 bits (132), Expect = 4e-007
Identities = 39/123 (31%), Positives = 58/123 (47%), Gaps = 14/123 (11%)
Frame = +2
Query: 182 LYRGFGLSVMTYS-PSSAAWWASYGSSQRVIWRLLGYGSDSEATVAPSQSKIVLVQALGG 358
+Y+ GL+ YS P++ + + VI+ S + PS L+ L G
Sbjct: 173 IYQSEGLAAFYYSYPTTLVMNIPFAAFNFVIY------ESSTKFLNPSNEYNPLIHCLCG 226
Query: 359 IIAGATASSITTPLDTIKTRLQVMGHQ-------ENRPSAKQVVKDLIAQDGWKGFYRGL 517
I+G+T ++ITTPLD IKT LQ+ G Q + + + GWKGF+RG
Sbjct: 227 SISGSTCAAITTPLDCIKTVLQIRGSQTVSLEIMRKADTFSKAASAIYQVYGWKGFWRGW 286
Query: 518 GPR 526
PR
Sbjct: 287 KPR 289
>sp|P23500|MRS4_YEAST Mitochondrial RNA-splicing protein MRS4 OS=Saccharomyces
cerevisiae GN=MRS4 PE=1 SV=1
Length = 304
Score = 55 bits (132), Expect = 4e-007
Identities = 31/77 (40%), Positives = 45/77 (58%), Gaps = 7/77 (9%)
Frame = +2
Query: 317 PSQSKIVLVQALGGIIAGATASSITTPLDTIKTRLQVMGHQ-------ENRPSAKQVVKD 475
P S L+ L G I+GAT +++TTPLD IKT LQV G + ++ + + +
Sbjct: 203 PQNSYNPLIHCLCGGISGATCAALTTPLDCIKTVLQVRGSETVSIEIMKDANTFGRASRA 262
Query: 476 LIAQDGWKGFYRGLGPR 526
++ GWKGF+RGL PR
Sbjct: 263 ILEVHGWKGFWRGLKPR 279
>sp|A2R5A0|TPC1_ASPNC Mitochondrial thiamine pyrophosphate carrier 1
OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) GN=tpc1 PE=3
SV=1
Length = 321
Score = 54 bits (128), Expect = 1e-006
Identities = 29/89 (32%), Positives = 51/89 (57%), Gaps = 7/89 (7%)
Frame = +2
Query: 26 AGMTASLFSQAVFVPIDVVSQKLMVQG-------YSGHATYTGGIDVATKIIKSYGVRGL 184
AG+ AS+ S+ V P+D++ ++L VQG + Y G + I+++ G+RGL
Sbjct: 222 AGVIASVSSKTVMFPLDLIRKRLQVQGPTRQLYIHRNIPEYQGVFNTMKLILRTQGIRGL 281
Query: 185 YRGFGLSVMTYSPSSAAWWASYGSSQRVI 271
YRG +S+ +P+SA +Y +S R++
Sbjct: 282 YRGLTVSLFKAAPASAVTMWTYETSLRLL 310
>sp|Q59Q36|TPC1_CANAL Mitochondrial thiamine pyrophosphate carrier 1 OS=Candida
albicans GN=TPC1 PE=3 SV=1
Length = 301
Score = 52 bits (122), Expect = 6e-006
Identities = 26/84 (30%), Positives = 43/84 (51%), Gaps = 1/84 (1%)
Frame = +2
Query: 329 KIVLVQALGGIIAGATASSITTPLDTIKTRLQVMGHQENRP-SAKQVVKDLIAQDGWKGF 505
++ ++A+ G IAGAT+ IT PLDT++ R Q+ RP +A + ++ +G G
Sbjct: 206 RVPFIEAICGFIAGATSKGITFPLDTLRKRCQMCSVVHGRPYTASHIFVTILKNEGVFGL 265
Query: 506 YRGLGPRFFSMSAWGTSMILTYEY 577
Y+G G + + YEY
Sbjct: 266 YKGFGISVLKTAPTSAISLFMYEY 289
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 132,248,888,565
Number of Sequences: 518415
Number of Extensions: 132248888565
Number of Successful Extensions: 812634680
Number of sequences better than 0.0: 0
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