BLASTX 7.6.2
Query= UN33675 /QuerySize=1121
(1120 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q7LBC6|KDM3B_HUMAN Lysine-specific demethylase 3B OS=Homo sap... 137 2e-031
sp|Q6ZPY7|KDM3B_MOUSE Lysine-specific demethylase 3B OS=Mus musc... 136 5e-031
sp|Q6IRB8|KD3AA_XENLA Lysine-specific demethylase 3A-A OS=Xenopu... 135 8e-031
sp|Q63679|KDM3A_RAT Lysine-specific demethylase 3A OS=Rattus nor... 134 1e-030
sp|Q9Y4C1|KDM3A_HUMAN Lysine-specific demethylase 3A OS=Homo sap... 134 2e-030
sp|Q6PCM1|KDM3A_MOUSE Lysine-specific demethylase 3A OS=Mus musc... 133 2e-030
sp|Q5HZN1|KD3AB_XENLA Lysine-specific demethylase 3A-B OS=Xenopu... 133 3e-030
sp|Q5ZIX8|KDM3A_CHICK Lysine-specific demethylase 3A OS=Gallus g... 133 3e-030
sp|P97609|HAIR_RAT Protein hairless OS=Rattus norvegicus GN=Hr P... 65 8e-010
sp|Q61645|HAIR_MOUSE Protein hairless OS=Mus musculus GN=Hr PE=2... 65 1e-009
sp|O43593|HAIR_HUMAN Protein hairless OS=Homo sapiens GN=HR PE=1... 59 6e-008
>sp|Q7LBC6|KDM3B_HUMAN Lysine-specific demethylase 3B OS=Homo sapiens GN=KDM3B
PE=1 SV=1
Length = 1761
Score = 137 bits (343), Expect = 2e-031
Identities = 68/142 (47%), Positives = 93/142 (65%), Gaps = 4/142 (2%)
Frame = -2
Query: 852 GAVWDIFRREDVPKLIEYLKRHKHEFRHLYNEPVKSVSHPIHDQSMFLNEKQKKQLKEEF 673
GA+W I+ +D K+ E L++ E + N P PIHDQS +L++ +K+L EE+
Sbjct: 1611 GALWHIYAAKDAEKIRELLRKVGEE-QGQENPPDHD---PIHDQSWYLDQTLRKRLYEEY 1666
Query: 672 DIEPWTFEQHLGEAVFIPAGCPHQVRNIQSCIKVALDFVAPESVGECLRLTEEFRRLPKD 493
++ W Q LG+AVFIPAG PHQV N+ SCIKVA DFV+PE V C RLT+EFR L
Sbjct: 1667 GVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFRLTQEFRHLSNT 1726
Query: 492 HRSNEDKLELKKIVLHAASSAI 427
H ++EDKL++K I+ HA A+
Sbjct: 1727 HTNHEDKLQVKNIIYHAVKDAV 1748
>sp|Q6ZPY7|KDM3B_MOUSE Lysine-specific demethylase 3B OS=Mus musculus GN=Kdm3b
PE=1 SV=2
Length = 1562
Score = 136 bits (340), Expect = 5e-031
Identities = 68/142 (47%), Positives = 93/142 (65%), Gaps = 4/142 (2%)
Frame = -2
Query: 852 GAVWDIFRREDVPKLIEYLKRHKHEFRHLYNEPVKSVSHPIHDQSMFLNEKQKKQLKEEF 673
GA+W I+ +D K+ E L++ E + N P PIHDQS +L++ +K+L EE+
Sbjct: 1412 GALWHIYAAKDAEKIRELLRKVGEE-QGQENPPDHD---PIHDQSWYLDQILRKRLFEEY 1467
Query: 672 DIEPWTFEQHLGEAVFIPAGCPHQVRNIQSCIKVALDFVAPESVGECLRLTEEFRRLPKD 493
++ W Q LG+AVFIPAG PHQV N+ SCIKVA DFV+PE V C RLT+EFR L
Sbjct: 1468 GVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFRLTQEFRHLSNT 1527
Query: 492 HRSNEDKLELKKIVLHAASSAI 427
H ++EDKL++K I+ HA A+
Sbjct: 1528 HTNHEDKLQVKNIIYHAVKDAV 1549
>sp|Q6IRB8|KD3AA_XENLA Lysine-specific demethylase 3A-A OS=Xenopus laevis
GN=kdm3a-a PE=2 SV=1
Length = 1331
Score = 135 bits (338), Expect = 8e-031
Identities = 72/149 (48%), Positives = 95/149 (63%), Gaps = 6/149 (4%)
Frame = -2
Query: 852 GAVWDIFRREDVPKLIEYLKRHKHEFRHLYNEPVKSVSHPIHDQSMFLNEKQKKQLKEEF 673
GA+W IF +D K+ ++LK+ E H N P PIHDQS +L+ +K+L +E
Sbjct: 1181 GALWHIFAAKDTEKIRQFLKKVAEEQGH-ENPPDHD---PIHDQSWYLDNTLRKRLLQEH 1236
Query: 672 DIEPWTFEQHLGEAVFIPAGCPHQVRNIQSCIKVALDFVAPESVGECLRLTEEFRRLPKD 493
++ W Q LG+AVFIPAG PHQV N+ SCIKVA DFV+PE V C LT+EFR L
Sbjct: 1237 GVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRYLSHT 1296
Query: 492 HRSNEDKLELKKIVLHAA--SSAIRDANE 412
H ++EDKL++K ++ HA S AI ANE
Sbjct: 1297 HTNHEDKLQVKNVIYHAVKDSIAILKANE 1325
>sp|Q63679|KDM3A_RAT Lysine-specific demethylase 3A OS=Rattus norvegicus
GN=Kdm3a PE=2 SV=1
Length = 1214
Score = 134 bits (336), Expect = 1e-030
Identities = 63/142 (44%), Positives = 91/142 (64%), Gaps = 4/142 (2%)
Frame = -2
Query: 852 GAVWDIFRREDVPKLIEYLKRHKHEFRHLYNEPVKSVSHPIHDQSMFLNEKQKKQLKEEF 673
GA+W I+ +D K+ E+LK+ E + + PIHDQS +L+ +K+L +E+
Sbjct: 1057 GALWHIYAAKDTEKIREFLKKVSEE----QGQENPADHDPIHDQSWYLDRSLRKRLYQEY 1112
Query: 672 DIEPWTFEQHLGEAVFIPAGCPHQVRNIQSCIKVALDFVAPESVGECLRLTEEFRRLPKD 493
++ W Q LG+ VFIPAG PHQV N+ SCIKVA DFV+PE V C LT+EFR L +
Sbjct: 1113 GVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRHLSQT 1172
Query: 492 HRSNEDKLELKKIVLHAASSAI 427
H ++EDKL++K ++ HA A+
Sbjct: 1173 HTNHEDKLQVKNVIYHAVKDAV 1194
>sp|Q9Y4C1|KDM3A_HUMAN Lysine-specific demethylase 3A OS=Homo sapiens GN=KDM3A
PE=1 SV=3
Length = 1321
Score = 134 bits (335), Expect = 2e-030
Identities = 63/142 (44%), Positives = 91/142 (64%), Gaps = 4/142 (2%)
Frame = -2
Query: 852 GAVWDIFRREDVPKLIEYLKRHKHEFRHLYNEPVKSVSHPIHDQSMFLNEKQKKQLKEEF 673
GA+W I+ +D K+ E+LK+ E + + PIHDQS +L+ +K+L +E+
Sbjct: 1171 GALWHIYAAKDTEKIREFLKKVSEE----QGQENPADHDPIHDQSWYLDRSLRKRLHQEY 1226
Query: 672 DIEPWTFEQHLGEAVFIPAGCPHQVRNIQSCIKVALDFVAPESVGECLRLTEEFRRLPKD 493
++ W Q LG+ VFIPAG PHQV N+ SCIKVA DFV+PE V C LT+EFR L +
Sbjct: 1227 GVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRYLSQT 1286
Query: 492 HRSNEDKLELKKIVLHAASSAI 427
H ++EDKL++K ++ HA A+
Sbjct: 1287 HTNHEDKLQVKNVIYHAVKDAV 1308
>sp|Q6PCM1|KDM3A_MOUSE Lysine-specific demethylase 3A OS=Mus musculus GN=Kdm3a
PE=1 SV=1
Length = 1323
Score = 133 bits (334), Expect = 2e-030
Identities = 63/142 (44%), Positives = 91/142 (64%), Gaps = 4/142 (2%)
Frame = -2
Query: 852 GAVWDIFRREDVPKLIEYLKRHKHEFRHLYNEPVKSVSHPIHDQSMFLNEKQKKQLKEEF 673
GA+W I+ +D K+ E+LK+ E + + PIHDQS +L+ +K+L +E+
Sbjct: 1173 GALWHIYAAKDTEKIREFLKKVSEE----QGQDNPADHDPIHDQSWYLDRSLRKRLYQEY 1228
Query: 672 DIEPWTFEQHLGEAVFIPAGCPHQVRNIQSCIKVALDFVAPESVGECLRLTEEFRRLPKD 493
++ W Q LG+ VFIPAG PHQV N+ SCIKVA DFV+PE V C LT+EFR L +
Sbjct: 1229 GVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRYLSQT 1288
Query: 492 HRSNEDKLELKKIVLHAASSAI 427
H ++EDKL++K ++ HA A+
Sbjct: 1289 HTNHEDKLQVKNVIYHAVKDAV 1310
>sp|Q5HZN1|KD3AB_XENLA Lysine-specific demethylase 3A-B OS=Xenopus laevis
GN=kdm3a-b PE=2 SV=1
Length = 1334
Score = 133 bits (333), Expect = 3e-030
Identities = 71/149 (47%), Positives = 95/149 (63%), Gaps = 6/149 (4%)
Frame = -2
Query: 852 GAVWDIFRREDVPKLIEYLKRHKHEFRHLYNEPVKSVSHPIHDQSMFLNEKQKKQLKEEF 673
GA+W I+ +D K+ ++LK+ E H N P PIHDQS +L+ +K+L +E
Sbjct: 1184 GALWHIYAAKDTEKIRQFLKKVAEEEGH-ENPPDHD---PIHDQSWYLDNILRKRLLQEH 1239
Query: 672 DIEPWTFEQHLGEAVFIPAGCPHQVRNIQSCIKVALDFVAPESVGECLRLTEEFRRLPKD 493
++ W Q LG+AVFIPAG PHQV N+ SCIKVA DFV+PE V C LT+EFR L
Sbjct: 1240 GVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFCLTQEFRYLSHT 1299
Query: 492 HRSNEDKLELKKIVLHAA--SSAIRDANE 412
H ++EDKL++K ++ HA S AI ANE
Sbjct: 1300 HTNHEDKLQVKNVIYHAVKDSIAILKANE 1328
>sp|Q5ZIX8|KDM3A_CHICK Lysine-specific demethylase 3A OS=Gallus gallus GN=KDM3A
PE=2 SV=1
Length = 1325
Score = 133 bits (333), Expect = 3e-030
Identities = 65/143 (45%), Positives = 90/143 (62%), Gaps = 6/143 (4%)
Frame = -2
Query: 852 GAVWDIFRREDVPKLIEYLKRHKHEFRHLYNEPVKSVSH-PIHDQSMFLNEKQKKQLKEE 676
GA+W I+ +D K+ E+LK+ E V H PIHDQS +L+ +K+L +E
Sbjct: 1175 GALWHIYAAKDTEKIREFLKKVAEE-----QGQENPVDHDPIHDQSWYLDRSLRKRLHQE 1229
Query: 675 FDIEPWTFEQHLGEAVFIPAGCPHQVRNIQSCIKVALDFVAPESVGECLRLTEEFRRLPK 496
+ ++ W Q LG+ VFIPAG PHQV N+ SCIKVA DFV+PE V C LT+EFR L
Sbjct: 1230 YGVQGWAIVQFLGDVVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFWLTQEFRYLSH 1289
Query: 495 DHRSNEDKLELKKIVLHAASSAI 427
H ++EDKL++K ++ HA A+
Sbjct: 1290 THTNHEDKLQVKNVIYHAVKDAV 1312
>sp|P97609|HAIR_RAT Protein hairless OS=Rattus norvegicus GN=Hr PE=2 SV=2
Length = 1181
Score = 65 bits (157), Expect = 8e-010
Identities = 31/78 (39%), Positives = 47/78 (60%)
Frame = -2
Query: 720 SMFLNEKQKKQLKEEFDIEPWTFEQHLGEAVFIPAGCPHQVRNIQSCIKVALDFVAPESV 541
S +L+ +++L+EE+ + WT Q GEAV +PAG PHQV+ + S I V F++PE+
Sbjct: 1079 SCYLDSGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTISVTQHFLSPETS 1138
Query: 540 GECLRLTEEFRRLPKDHR 487
+L + LP DHR
Sbjct: 1139 ALSAQLCHQGASLPPDHR 1156
>sp|Q61645|HAIR_MOUSE Protein hairless OS=Mus musculus GN=Hr PE=2 SV=2
Length = 1182
Score = 65 bits (156), Expect = 1e-009
Identities = 34/98 (34%), Positives = 56/98 (57%), Gaps = 2/98 (2%)
Frame = -2
Query: 720 SMFLNEKQKKQLKEEFDIEPWTFEQHLGEAVFIPAGCPHQVRNIQSCIKVALDFVAPESV 541
S +L+ +++L+EE+ + WT Q GEAV +PAG PHQV+ + S I V F++PE+
Sbjct: 1080 SCYLDAGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTISVTQHFLSPETS 1139
Query: 540 GECLRLTEEFRRLPKDHRSNEDKLELKKIVLHAASSAI 427
+L + LP DHR +++ + V A +A+
Sbjct: 1140 ALSAQLYHQGASLPPDHRMLYAQMD--RAVFQAVKAAV 1175
>sp|O43593|HAIR_HUMAN Protein hairless OS=Homo sapiens GN=HR PE=1 SV=5
Length = 1189
Score = 59 bits (141), Expect = 6e-008
Identities = 28/76 (36%), Positives = 45/76 (59%)
Frame = -2
Query: 720 SMFLNEKQKKQLKEEFDIEPWTFEQHLGEAVFIPAGCPHQVRNIQSCIKVALDFVAPESV 541
S +L+ +++L+EE+ + WT Q GEAV +PAG PHQV+ + S + V F++PE+
Sbjct: 1087 SCYLDAGLRRRLREEWGVSCWTLLQAPGEAVLVPAGAPHQVQGLVSTVSVTQHFLSPETS 1146
Query: 540 GECLRLTEEFRRLPKD 493
+L + LP D
Sbjct: 1147 ALSAQLCHQGPSLPPD 1162
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 133,255,942,245
Number of Sequences: 518415
Number of Extensions: 133255942245
Number of Successful Extensions: 824475253
Number of sequences better than 0.0: 0
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