BLASTX 7.6.2
Query= UN33747 /QuerySize=803
(802 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P23685|NAC1_CANFA Sodium/calcium exchanger 1 OS=Canis familia... 86 2e-016
sp|P48766|NAC1_CAVPO Sodium/calcium exchanger 1 OS=Cavia porcell... 86 2e-016
sp|P48767|NAC1_FELCA Sodium/calcium exchanger 1 OS=Felis catus G... 86 2e-016
sp|P32418|NAC1_HUMAN Sodium/calcium exchanger 1 OS=Homo sapiens ... 86 2e-016
sp|P70414|NAC1_MOUSE Sodium/calcium exchanger 1 OS=Mus musculus ... 86 2e-016
sp|Q01728|NAC1_RAT Sodium/calcium exchanger 1 OS=Rattus norvegic... 86 2e-016
sp|P48765|NAC1_BOVIN Sodium/calcium exchanger 1 OS=Bos taurus GN... 84 8e-016
sp|Q99PD7|NCKX3_MOUSE Sodium/potassium/calcium exchanger 3 OS=Mu... 54 1e-006
sp|Q9EPQ0|NCKX3_RAT Sodium/potassium/calcium exchanger 3 (Fragme... 54 1e-006
sp|Q49SH1|NCKX5_DANRE Sodium/potassium/calcium exchanger 5 OS=Da... 54 1e-006
sp|Q9HC58|NCKX3_HUMAN Sodium/potassium/calcium exchanger 3 OS=Ho... 51 9e-006
>sp|P23685|NAC1_CANFA Sodium/calcium exchanger 1 OS=Canis familiaris GN=SLC8A1
PE=1 SV=1
Length = 970
Score = 86 bits (212), Expect = 2e-016
Identities = 46/110 (41%), Positives = 62/110 (56%), Gaps = 3/110 (2%)
Frame = +3
Query: 84 WKILFAFVPPCNIAHGWIAFICSLLFISGVAFVVTRLTDLISCVTGINPYVIAFTALAAG 263
WK+LFAFVPP +GW FI S+L I + + L C G+ V A +A G
Sbjct: 782 WKVLFAFVPPTEYWNGWACFIVSILMIGILTAFIGDLASHFGCTIGLKDSVTAVVFVALG 841
Query: 264 TSWPDLVASKIAAERQLTADSAIANITCSNSVNIY---GGDWSSVADKHS 404
TS PD ASK+AA + AD++I N+T SN+VN++ G WS A H+
Sbjct: 842 TSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHA 891
Score = 55 bits (130), Expect = 6e-007
Identities = 35/88 (39%), Positives = 48/88 (54%), Gaps = 3/88 (3%)
Frame = +1
Query: 370 VGIGVPWLINTVYNYFAYREPLYIENAKGISFSLLIFFA-TSVGCIVVLVLRRVIIGAEL 546
+GIGV W I +Y+ + S +L FA +VG V+L RR IG EL
Sbjct: 877 LGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVG--VLLYRRRPEIGGEL 934
Query: 547 GGPRLWAWLTSAYFMVLWLVFVVLSSLK 630
GGPR LTS F++LWL+++ SSL+
Sbjct: 935 GGPRTAKLLTSCLFVLLWLLYIFFSSLE 962
>sp|P48766|NAC1_CAVPO Sodium/calcium exchanger 1 OS=Cavia porcellus GN=SLC8A1
PE=2 SV=1
Length = 970
Score = 86 bits (212), Expect = 2e-016
Identities = 46/110 (41%), Positives = 62/110 (56%), Gaps = 3/110 (2%)
Frame = +3
Query: 84 WKILFAFVPPCNIAHGWIAFICSLLFISGVAFVVTRLTDLISCVTGINPYVIAFTALAAG 263
WK+LFAFVPP +GW FI S+L I + + L C G+ V A +A G
Sbjct: 782 WKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALG 841
Query: 264 TSWPDLVASKIAAERQLTADSAIANITCSNSVNIY---GGDWSSVADKHS 404
TS PD ASK+AA + AD++I N+T SN+VN++ G WS A H+
Sbjct: 842 TSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHA 891
Score = 55 bits (130), Expect = 6e-007
Identities = 35/88 (39%), Positives = 48/88 (54%), Gaps = 3/88 (3%)
Frame = +1
Query: 370 VGIGVPWLINTVYNYFAYREPLYIENAKGISFSLLIFFA-TSVGCIVVLVLRRVIIGAEL 546
+GIGV W I +Y+ + S +L FA +VG V+L RR IG EL
Sbjct: 877 LGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVG--VLLYRRRPEIGGEL 934
Query: 547 GGPRLWAWLTSAYFMVLWLVFVVLSSLK 630
GGPR LTS F++LWL+++ SSL+
Sbjct: 935 GGPRTAKLLTSCLFVLLWLLYIFFSSLE 962
>sp|P48767|NAC1_FELCA Sodium/calcium exchanger 1 OS=Felis catus GN=SLC8A1 PE=2
SV=1
Length = 970
Score = 86 bits (212), Expect = 2e-016
Identities = 46/110 (41%), Positives = 62/110 (56%), Gaps = 3/110 (2%)
Frame = +3
Query: 84 WKILFAFVPPCNIAHGWIAFICSLLFISGVAFVVTRLTDLISCVTGINPYVIAFTALAAG 263
WK+LFAFVPP +GW FI S+L I + + L C G+ V A +A G
Sbjct: 782 WKVLFAFVPPTEYWNGWACFIVSILMIGILTAFIGDLASHFGCTIGLKDSVTAVVFVALG 841
Query: 264 TSWPDLVASKIAAERQLTADSAIANITCSNSVNIY---GGDWSSVADKHS 404
TS PD ASK+AA + AD++I N+T SN+VN++ G WS A H+
Sbjct: 842 TSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHA 891
Score = 55 bits (130), Expect = 6e-007
Identities = 35/88 (39%), Positives = 48/88 (54%), Gaps = 3/88 (3%)
Frame = +1
Query: 370 VGIGVPWLINTVYNYFAYREPLYIENAKGISFSLLIFFA-TSVGCIVVLVLRRVIIGAEL 546
+GIGV W I +Y+ + S +L FA +VG V+L RR IG EL
Sbjct: 877 LGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVG--VLLYRRRPEIGGEL 934
Query: 547 GGPRLWAWLTSAYFMVLWLVFVVLSSLK 630
GGPR LTS F++LWL+++ SSL+
Sbjct: 935 GGPRTAKLLTSCLFVLLWLLYIFFSSLE 962
>sp|P32418|NAC1_HUMAN Sodium/calcium exchanger 1 OS=Homo sapiens GN=SLC8A1 PE=1
SV=3
Length = 973
Score = 86 bits (212), Expect = 2e-016
Identities = 46/110 (41%), Positives = 62/110 (56%), Gaps = 3/110 (2%)
Frame = +3
Query: 84 WKILFAFVPPCNIAHGWIAFICSLLFISGVAFVVTRLTDLISCVTGINPYVIAFTALAAG 263
WK+LFAFVPP +GW FI S+L I + + L C G+ V A +A G
Sbjct: 785 WKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALG 844
Query: 264 TSWPDLVASKIAAERQLTADSAIANITCSNSVNIY---GGDWSSVADKHS 404
TS PD ASK+AA + AD++I N+T SN+VN++ G WS A H+
Sbjct: 845 TSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHA 894
Score = 55 bits (130), Expect = 6e-007
Identities = 35/88 (39%), Positives = 48/88 (54%), Gaps = 3/88 (3%)
Frame = +1
Query: 370 VGIGVPWLINTVYNYFAYREPLYIENAKGISFSLLIFFA-TSVGCIVVLVLRRVIIGAEL 546
+GIGV W I +Y+ + S +L FA +VG V+L RR IG EL
Sbjct: 880 LGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVG--VLLYRRRPEIGGEL 937
Query: 547 GGPRLWAWLTSAYFMVLWLVFVVLSSLK 630
GGPR LTS F++LWL+++ SSL+
Sbjct: 938 GGPRTAKLLTSCLFVLLWLLYIFFSSLE 965
>sp|P70414|NAC1_MOUSE Sodium/calcium exchanger 1 OS=Mus musculus GN=Slc8a1 PE=1
SV=1
Length = 970
Score = 86 bits (212), Expect = 2e-016
Identities = 46/110 (41%), Positives = 62/110 (56%), Gaps = 3/110 (2%)
Frame = +3
Query: 84 WKILFAFVPPCNIAHGWIAFICSLLFISGVAFVVTRLTDLISCVTGINPYVIAFTALAAG 263
WK+LFAFVPP +GW FI S+L I + + L C G+ V A +A G
Sbjct: 782 WKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALG 841
Query: 264 TSWPDLVASKIAAERQLTADSAIANITCSNSVNIY---GGDWSSVADKHS 404
TS PD ASK+AA + AD++I N+T SN+VN++ G WS A H+
Sbjct: 842 TSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHA 891
Score = 55 bits (131), Expect = 5e-007
Identities = 35/88 (39%), Positives = 49/88 (55%), Gaps = 3/88 (3%)
Frame = +1
Query: 370 VGIGVPWLINTVYNYFAYREPLYIENAKGISFSLLIFFA-TSVGCIVVLVLRRVIIGAEL 546
+GIGV W I +Y+ + S +L FA +VG V+L RR IG EL
Sbjct: 877 LGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVG--VLLYRRRPEIGGEL 934
Query: 547 GGPRLWAWLTSAYFMVLWLVFVVLSSLK 630
GGPR LTS+ F++LWL+++ SSL+
Sbjct: 935 GGPRTAKLLTSSLFVLLWLLYIFFSSLE 962
>sp|Q01728|NAC1_RAT Sodium/calcium exchanger 1 OS=Rattus norvegicus GN=Slc8a1
PE=2 SV=3
Length = 971
Score = 86 bits (212), Expect = 2e-016
Identities = 46/110 (41%), Positives = 62/110 (56%), Gaps = 3/110 (2%)
Frame = +3
Query: 84 WKILFAFVPPCNIAHGWIAFICSLLFISGVAFVVTRLTDLISCVTGINPYVIAFTALAAG 263
WK+LFAFVPP +GW FI S+L I + + L C G+ V A +A G
Sbjct: 783 WKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFGCTIGLKDSVTAVVFVALG 842
Query: 264 TSWPDLVASKIAAERQLTADSAIANITCSNSVNIY---GGDWSSVADKHS 404
TS PD ASK+AA + AD++I N+T SN+VN++ G WS A H+
Sbjct: 843 TSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHA 892
Score = 55 bits (131), Expect = 5e-007
Identities = 35/88 (39%), Positives = 49/88 (55%), Gaps = 3/88 (3%)
Frame = +1
Query: 370 VGIGVPWLINTVYNYFAYREPLYIENAKGISFSLLIFFA-TSVGCIVVLVLRRVIIGAEL 546
+GIGV W I +Y+ + S +L FA +VG V+L RR IG EL
Sbjct: 878 LGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVG--VLLYRRRPEIGGEL 935
Query: 547 GGPRLWAWLTSAYFMVLWLVFVVLSSLK 630
GGPR LTS+ F++LWL+++ SSL+
Sbjct: 936 GGPRTAKLLTSSLFVLLWLLYIFFSSLE 963
>sp|P48765|NAC1_BOVIN Sodium/calcium exchanger 1 OS=Bos taurus GN=SLC8A1 PE=1
SV=1
Length = 970
Score = 84 bits (207), Expect = 8e-016
Identities = 45/110 (40%), Positives = 62/110 (56%), Gaps = 3/110 (2%)
Frame = +3
Query: 84 WKILFAFVPPCNIAHGWIAFICSLLFISGVAFVVTRLTDLISCVTGINPYVIAFTALAAG 263
WK+LFAFVPP +GW FI S+L I + + L +C + V A +A G
Sbjct: 782 WKVLFAFVPPTEYWNGWACFIVSILMIGLLTAFIGDLASHFACTIALKDSVTAVVFVALG 841
Query: 264 TSWPDLVASKIAAERQLTADSAIANITCSNSVNIY---GGDWSSVADKHS 404
TS PD ASK+AA + AD++I N+T SN+VN++ G WS A H+
Sbjct: 842 TSVPDTFASKVAATQDQYADASIGNVTGSNAVNVFLGIGVAWSIAAIYHA 891
Score = 55 bits (130), Expect = 6e-007
Identities = 35/88 (39%), Positives = 48/88 (54%), Gaps = 3/88 (3%)
Frame = +1
Query: 370 VGIGVPWLINTVYNYFAYREPLYIENAKGISFSLLIFFA-TSVGCIVVLVLRRVIIGAEL 546
+GIGV W I +Y+ + S +L FA +VG V+L RR IG EL
Sbjct: 877 LGIGVAWSIAAIYHAANGEQFKVSPGTLAFSVTLFTIFAFINVG--VLLYRRRPEIGGEL 934
Query: 547 GGPRLWAWLTSAYFMVLWLVFVVLSSLK 630
GGPR LTS F++LWL+++ SSL+
Sbjct: 935 GGPRTAKLLTSCLFVLLWLLYIFFSSLE 962
>sp|Q99PD7|NCKX3_MOUSE Sodium/potassium/calcium exchanger 3 OS=Mus musculus
GN=Slc24a3 PE=2 SV=2
Length = 645
Score = 54 bits (128), Expect = 1e-006
Identities = 43/136 (31%), Positives = 66/136 (48%), Gaps = 11/136 (8%)
Frame = +3
Query: 90 ILFAFVPPCNIAHGW-----IAFICSLLFISGVAFVVTRLTDLISCVTGINPYVIAFTAL 254
+L+ VP CN H W + F S L+I+ ++++ + +I GI ++ T L
Sbjct: 461 VLYFTVPNCNKPH-WEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFL 519
Query: 255 AAGTSWPDLVASKIAAERQLTADSAIANITCSNSVNIYGGDWSSVADKHSVQLLCIQRAS 434
AAGTS PD +AS I A RQ D A++N SN +I G + ++Q L + S
Sbjct: 520 AAGTSVPDCMASLIVA-RQGMGDMAVSNSIGSNVFDILIG----LGLPWALQTLAVDYGS 574
Query: 435 VHRKCERDKLLSADIL 482
R R + S +L
Sbjct: 575 YIRLNSRGLIYSVGLL 590
>sp|Q9EPQ0|NCKX3_RAT Sodium/potassium/calcium exchanger 3 (Fragment) OS=Rattus
norvegicus GN=Slc24a3 PE=2 SV=1
Length = 624
Score = 54 bits (128), Expect = 1e-006
Identities = 43/136 (31%), Positives = 66/136 (48%), Gaps = 11/136 (8%)
Frame = +3
Query: 90 ILFAFVPPCNIAHGW-----IAFICSLLFISGVAFVVTRLTDLISCVTGINPYVIAFTAL 254
+L+ VP CN H W + F S L+I+ ++++ + +I GI ++ T L
Sbjct: 440 VLYFTVPNCNKPH-WEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFL 498
Query: 255 AAGTSWPDLVASKIAAERQLTADSAIANITCSNSVNIYGGDWSSVADKHSVQLLCIQRAS 434
AAGTS PD +AS I A RQ D A++N SN +I G + ++Q L + S
Sbjct: 499 AAGTSVPDCMASLIVA-RQGMGDMAVSNSIGSNVFDILIG----LGLPWALQTLAVDYGS 553
Query: 435 VHRKCERDKLLSADIL 482
R R + S +L
Sbjct: 554 YIRLNSRGLIYSVGLL 569
>sp|Q49SH1|NCKX5_DANRE Sodium/potassium/calcium exchanger 5 OS=Danio rerio
GN=slc24a5 PE=2 SV=1
Length = 513
Score = 54 bits (127), Expect = 1e-006
Identities = 37/107 (34%), Positives = 55/107 (51%), Gaps = 7/107 (6%)
Frame = +3
Query: 48 IAKSFWQLVLAPWKILFAFVPPCNIAHGW-----IAFICSLLFISGVAFVVTRLTDLISC 212
+ + W L L +LF VP C W + F+ S ++IS +V+ + ++
Sbjct: 316 LKRILWVLSLPVSTLLFVSVPDCRRPF-WKNFYMLTFLMSAVWISAFTYVLVWMVTIVGE 374
Query: 213 VTGINPYVIAFTALAAGTSWPDLVASKIAAERQLTADSAIANITCSN 353
GI V+ T LAAGTS PD VAS + A R+ +D A++NI SN
Sbjct: 375 TLGIPDTVMGMTLLAAGTSIPDTVASVMVA-REGKSDMAMSNIVGSN 420
>sp|Q9HC58|NCKX3_HUMAN Sodium/potassium/calcium exchanger 3 OS=Homo sapiens
GN=SLC24A3 PE=2 SV=4
Length = 644
Score = 51 bits (120), Expect = 9e-006
Identities = 42/136 (30%), Positives = 65/136 (47%), Gaps = 11/136 (8%)
Frame = +3
Query: 90 ILFAFVPPCNIAHGW-----IAFICSLLFISGVAFVVTRLTDLISCVTGINPYVIAFTAL 254
+L+ VP CN W + F S L+I+ ++++ + +I GI ++ T L
Sbjct: 459 VLYFTVPNCNKPR-WEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVIMGITFL 517
Query: 255 AAGTSWPDLVASKIAAERQLTADSAIANITCSNSVNIYGGDWSSVADKHSVQLLCIQRAS 434
AAGTS PD +AS I A RQ D A++N SN +I G + ++Q L + S
Sbjct: 518 AAGTSVPDCMASLIVA-RQGMGDMAVSNSIGSNVFDILIG----LGLPWALQTLAVDYGS 572
Query: 435 VHRKCERDKLLSADIL 482
R R + S +L
Sbjct: 573 YIRLNSRGLIYSVGLL 588
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 133,255,942,245
Number of Sequences: 518415
Number of Extensions: 133255942245
Number of Successful Extensions: 824475253
Number of sequences better than 0.0: 0
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