BLASTX 7.6.2
Query= UN33775 /QuerySize=1113
(1112 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8BMG8|MFTC_MOUSE Mitochondrial folate transporter/carrier OS... 199 5e-050
sp|Q54QN2|MCFM_DICDI Mitochondrial substrate carrier family prot... 126 4e-028
sp|Q76P23|PM34_DICDI Mitochondrial substrate carrier family prot... 120 3e-026
sp|Q9H2D1|MFTC_HUMAN Mitochondrial folate transporter/carrier OS... 113 3e-024
sp|Q95J75|MFTC_MACFA Mitochondrial folate transporter/carrier OS... 112 6e-024
sp|P39953|YEA6_YEAST Probable mitochondrial carrier YEL006W OS=S... 99 5e-020
sp|P40556|YIA6_YEAST Uncharacterized mitochondrial carrier YIL00... 98 8e-020
sp|Q54BM3|MCFG_DICDI Mitochondrial substrate carrier family prot... 96 3e-019
sp|Q9P6L7|YKQ9_SCHPO Uncharacterized mitochondrial carrier C688.... 91 1e-017
sp|A6RF73|TPC1_AJECN Mitochondrial thiamine pyrophosphate carrie... 86 6e-016
sp|O43808|PM34_HUMAN Peroxisomal membrane protein PMP34 OS=Homo ... 80 3e-014
sp|Q4X022|TPC1_ASPFU Mitochondrial thiamine pyrophosphate carrie... 79 5e-014
sp|A1DI57|TPC1_NEOFI Mitochondrial thiamine pyrophosphate carrie... 77 2e-013
sp|O70579|PM34_MOUSE Peroxisomal membrane protein PMP34 OS=Mus m... 77 3e-013
sp|B0G159|MCFC_DICDI Mitochondrial substrate carrier family prot... 75 8e-013
sp|A2R5A0|TPC1_ASPNC Mitochondrial thiamine pyrophosphate carrie... 75 8e-013
sp|A4RF23|TPC1_MAGGR Mitochondrial thiamine pyrophosphate carrie... 73 4e-012
sp|A6SL61|TPC1_BOTFB Mitochondrial thiamine pyrophosphate carrie... 72 5e-012
sp|O94502|YBT5_SCHPO Uncharacterized mitochondrial carrier C12D1... 71 1e-011
sp|A7ER02|TPC1_SCLS1 Mitochondrial thiamine pyrophosphate carrie... 70 2e-011
>sp|Q8BMG8|MFTC_MOUSE Mitochondrial folate transporter/carrier OS=Mus musculus
GN=Slc25a32 PE=2 SV=1
Length = 316
Score = 199 bits (504), Expect = 5e-050
Identities = 130/301 (43%), Positives = 167/301 (55%), Gaps = 32/301 (10%)
Frame = -1
Query: 983 WENATAGAVAGFATVAAMHPLDVVRTRFQVNDGRGLSALPTYKNTAHALFTIARLEGLRG 804
+EN AG G + A+HPLD+V+ RF V+D GL P YK H L TI +++GLR
Sbjct: 23 YENLVAGVSGGVLSNLALHPLDLVKIRFAVSD--GLEVRPKYKGILHCLATIWKVDGLR- 79
Query: 803 GLYAGFFPAVIGSTLSWSLYFFFYGRAKQRYGRGRDDDKLTPPLHLASAAEAGAL----- 639
GLY G P V G+ LSW LYFFFY K GR ++L P +L SAAEAGA+
Sbjct: 80 GLYQGVTPNVWGAGLSWGLYFFFYNAIKSYKTEGR-AEQLEPLEYLVSAAEAGAMTLCIT 138
Query: 638 -------TRLQLQTPLHQTP---PYSGLLDAFRTIIKEEGPRALYKGILPALLLVSHGAI 489
TRL LQ +P Y G+ DA I K EG R LYKG +P L SHGA+
Sbjct: 139 NPLWVTKTRLMLQYGGVASPSQRQYKGMFDALVKIYKYEGVRGLYKGFVPGLFGTSHGAL 198
Query: 488 QFTAYEELRKLIVDFKDKRRNSESTSDNLLNSADYAALGDSSKVATVLLTYPFQVIRARL 309
QF AYE L+ ++ + L++A+Y ++ SK+ V TYP+QV+RARL
Sbjct: 199 QFMAYELLK------LKYNKHINRLPEAQLSTAEYISVAALSKIFAVAATYPYQVVRARL 252
Query: 308 Q-QRPSTNGVPRYIDSLHVIRETARFEGVRGFYRGLTANLLKNVPASSITFIVYENVLKL 132
Q Q S GV VI +T R EG+ GFY+G+ NL++ PA ITF+VYENV
Sbjct: 253 QDQHVSYGGV------TDVITKTWRKEGIGGFYKGIAPNLIRVTPACCITFVVYENVSHF 306
Query: 131 L 129
L
Sbjct: 307 L 307
>sp|Q54QN2|MCFM_DICDI Mitochondrial substrate carrier family protein M
OS=Dictyostelium discoideum GN=mcfM PE=3 SV=1
Length = 306
Score = 126 bits (315), Expect = 4e-028
Identities = 92/303 (30%), Positives = 143/303 (47%), Gaps = 40/303 (13%)
Frame = -1
Query: 971 TAGAVAGFATVAAMHPLDVVRTRFQ---------VNDGRGLSALPTYKNTAHALFTIARL 819
T+ + A + P D ++ R Q +N + + + T KN + +
Sbjct: 12 TSALLGSTVATAFLQPFDFLKIRLQGSGFASGGDLNKFKRVGVIDTCKN-------VLKN 64
Query: 818 EGLRGGLYAGFFPAVIGSTLSWSLYFFFYGRAKQRYGRGRDDDKLTPPLHLASAAEAGAL 639
EG++ + G P ++ S ++W Y FY K + +L H A A A
Sbjct: 65 EGIK-QFWRGSSPTIVASGIAWGTYMHFYEAYKNILKSKYNVTQLNTFDHFICAVGASAT 123
Query: 638 ------------TRLQLQTPLHQTPPYSGLLDAFRTIIKEEGPRALYKGILPALLLVSHG 495
TR+QLQTP Y+G+ D + +K EG + LYKG++P+L L HG
Sbjct: 124 QVFITNPIFLIKTRMQLQTP-GSANYYTGIFDGIKKTVKVEGFKGLYKGVIPSLWLTFHG 182
Query: 494 AIQFTAYEELRKLIVDFKDKRRNSESTSDNLLNSADYAALGDSSKVATVLLTYPFQVIRA 315
IQ ++YE ++ NS + D+L S + A S +A+ +L YPFQV++
Sbjct: 183 GIQMSSYEHIKFYF------SSNSGKSLDSLNASEIFIASSISKFLASTIL-YPFQVVKT 235
Query: 314 RLQQR---PSTNGVPRYIDSLHVIRETARFEGVRGFYRGLTANLLKNVPASSITFIVYEN 144
RLQ P+ N V Y + VI + + EG+ GFYRGL N LK +P +SIT ++YE
Sbjct: 236 RLQDERNIPNQNNVRVYNGTKDVIFKILKNEGIIGFYRGLVPNTLKVIPNTSITLLLYEE 295
Query: 143 VLK 135
+ K
Sbjct: 296 IKK 298
>sp|Q76P23|PM34_DICDI Mitochondrial substrate carrier family protein Q
OS=Dictyostelium discoideum GN=mcfQ PE=2 SV=1
Length = 329
Score = 120 bits (299), Expect = 3e-026
Identities = 92/304 (30%), Positives = 154/304 (50%), Gaps = 42/304 (13%)
Frame = -1
Query: 977 NATAGAVAGFATVAAMHPLDVVRTRFQVNDGR-------GLSALPTYKNTAHALFTIARL 819
+A +G VAG A +A +P V TR QV + ++ +P YKN+ A I +
Sbjct: 23 HAISGGVAGMAAIALTYPFSTVSTRLQVQQKKQQQGQQSEITTVP-YKNSIDAFKRIIKE 81
Query: 818 EGLRGGLYAGFFPAVIGSTLSWSLYFFFYGRAKQRYGRGRDDDKLTPPLHLASAAEAGAL 639
E R LY+G A+IG S +Y+++Y K + ++ +L +LA AA AG
Sbjct: 82 ENWR-TLYSGLKSALIGIGASSFVYYYWYTLLKSISLKLKNKQELGTIENLAIAALAGCA 140
Query: 638 ------------TRLQLQTPLHQTPPYSGLLDAFRTIIKEEGPRALYKGILPALLLVSHG 495
TRLQ+ + G++ F+ IIK EG LYKG++PAL+LVS+
Sbjct: 141 NVLTTLPIWVVNTRLQINSD-------KGIVGQFKYIIKNEGFGGLYKGLIPALILVSNP 193
Query: 494 AIQFTAYEELRKLIVDFKDKRRNSESTSDNLLNSADYAALGDSSKVATVLLTYPFQVIRA 315
++QF +YE+LR L RR S T L + LG +K+ ++TYP+ ++++
Sbjct: 194 SVQFVSYEKLRAL------WRRQSGRTK---LGGLEVFILGAIAKLIAGIVTYPYLLVKS 244
Query: 314 RLQQRPSTNGVP-----RYIDSLHVIRETARFEGVRGFYRGLTANLLKNVPASSITFIVY 150
RLQ + P +Y +L I + + +G GF++G+ + +++ V ++ F+V
Sbjct: 245 RLQSQSGNASNPESQQQQYKGTLDAIGKIFKSDGFLGFFKGMPSKMVQTVIGAAFMFLVK 304
Query: 149 ENVL 138
+ V+
Sbjct: 305 DKVV 308
>sp|Q9H2D1|MFTC_HUMAN Mitochondrial folate transporter/carrier OS=Homo sapiens
GN=SLC25A32 PE=1 SV=2
Length = 315
Score = 113 bits (281), Expect = 3e-024
Identities = 70/173 (40%), Positives = 93/173 (53%), Gaps = 14/173 (8%)
Frame = -1
Query: 638 TRLQLQTPLHQTPP---YSGLLDAFRTIIKEEGPRALYKGILPALLLVSHGAIQFTAYEE 468
TRL LQ P Y G+ D I K EG R LYKG +P L SHGA+QF AYE
Sbjct: 146 TRLMLQYDAVVNSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYEL 205
Query: 467 LRKLIVDFKDKRRNSESTSDNLLNSADYAALGDSSKVATVLLTYPFQVIRARLQQRPSTN 288
L+ ++ + L++ +Y ++ SK+ V TYP+QV+RARLQ +
Sbjct: 206 LK------LKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMF- 258
Query: 287 GVPRYIDSLHVIRETARFEGVRGFYRGLTANLLKNVPASSITFIVYENVLKLL 129
Y + VI +T R EGV GFY+G+ NL++ PA ITF+VYENV L
Sbjct: 259 ----YSGVIDVITKTWRKEGVGGFYKGIAPNLIRVTPACCITFVVYENVSHFL 307
>sp|Q95J75|MFTC_MACFA Mitochondrial folate transporter/carrier OS=Macaca
fascicularis GN=SLC25A32 PE=2 SV=1
Length = 315
Score = 112 bits (279), Expect = 6e-024
Identities = 69/173 (39%), Positives = 93/173 (53%), Gaps = 14/173 (8%)
Frame = -1
Query: 638 TRLQLQTPLHQTPP---YSGLLDAFRTIIKEEGPRALYKGILPALLLVSHGAIQFTAYEE 468
TRL LQ P Y G+ D I K EG R LYKG +P L SHGA+QF AYE
Sbjct: 146 TRLMLQYDAVINSPHRQYKGMFDTLVKIYKYEGVRGLYKGFVPGLFGTSHGALQFMAYEL 205
Query: 467 LRKLIVDFKDKRRNSESTSDNLLNSADYAALGDSSKVATVLLTYPFQVIRARLQQRPSTN 288
L+ ++ + L++ +Y ++ SK+ V TYP+QV+RARLQ +
Sbjct: 206 LK------LKYNQHINRLPEAQLSTVEYISVAALSKIFAVAATYPYQVVRARLQDQHMF- 258
Query: 287 GVPRYIDSLHVIRETARFEGVRGFYRGLTANLLKNVPASSITFIVYENVLKLL 129
Y + VI +T R EG+ GFY+G+ NL++ PA ITF+VYENV L
Sbjct: 259 ----YSGVIDVITKTWRKEGIGGFYKGIAPNLIRVTPACCITFVVYENVSHFL 307
>sp|P39953|YEA6_YEAST Probable mitochondrial carrier YEL006W OS=Saccharomyces
cerevisiae GN=YEL006W PE=1 SV=1
Length = 335
Score = 99 bits (245), Expect = 5e-020
Identities = 64/172 (37%), Positives = 94/172 (54%), Gaps = 7/172 (4%)
Frame = -1
Query: 638 TRLQLQTPLHQ-TPPYSGLLDAFRTIIKEEGPRALYKGILPALLLVSHGAIQFTAYEELR 462
TRL LQT + + + Y G +D FR II++EG +ALY G++PALL + + AIQF YE L+
Sbjct: 164 TRLMLQTGIGKYSTHYKGTIDTFRKIIQQEGAKALYAGLVPALLGMLNVAIQFPLYENLK 223
Query: 461 KLIVDFKDKRRNSESTSDNLLNSADYAALGDSSKVATVLLTYPFQVIRARLQQRPS-TNG 285
+ F ST N SK+ +TYP +++R R+Q + N
Sbjct: 224 ---IRFGYSESTDVSTDVTSSNFQKLILASMLSKMVASTVTYPHEILRTRMQLKSDLPNT 280
Query: 284 VPRYIDSLHVIRETARFEGVRGFYRGLTANLLKNVPASSITFIVYENVLKLL 129
V R++ L +I+ T R EG GFY G NL++ VPA+ +T + +E K L
Sbjct: 281 VQRHL--LPLIKITYRQEGFAGFYSGFATNLVRTVPAAVVTLVSFEYSKKYL 330
>sp|P40556|YIA6_YEAST Uncharacterized mitochondrial carrier YIL006W
OS=Saccharomyces cerevisiae GN=YIL006W PE=1 SV=1
Length = 373
Score = 98 bits (243), Expect = 8e-020
Identities = 62/167 (37%), Positives = 97/167 (58%), Gaps = 12/167 (7%)
Frame = -1
Query: 638 TRLQLQTPLHQTPP-YSGLLDAFRTIIKEEGPRALYKGILPALLLVSHGAIQFTAYEELR 462
TRL LQ+ L + P Y G DAFR + +EG +ALY G++P+LL + H AI F YE+L+
Sbjct: 202 TRLMLQSNLGEHPTHYKGTFDAFRKLFYQEGFKALYAGLVPSLLGLFHVAIHFPIYEDLK 261
Query: 461 KLIVDFKDKRRNSESTSDNLLNSADYAALGDSSKVATVLLTYPFQVIRARLQQRPSTNGV 282
V F R + + S NL +++ SK+ +TYP +++R R+Q + + +
Sbjct: 262 ---VRFHCYSRENNTNSINLQRLIMASSV---SKMIASAVTYPHEILRTRMQLK---SDI 312
Query: 281 PRYIDS--LHVIRETARFEGVRGFYRGLTANLLKNVPASSITFIVYE 147
P I +I+ T EG++GFY G T NL++ +PAS+IT + +E
Sbjct: 313 PDSIQRRLFPLIKATYAQEGLKGFYSGFTTNLVRTIPASAITLVSFE 359
>sp|Q54BM3|MCFG_DICDI Mitochondrial substrate carrier family protein G
OS=Dictyostelium discoideum GN=mcfG PE=2 SV=1
Length = 300
Score = 96 bits (238), Expect = 3e-019
Identities = 75/299 (25%), Positives = 128/299 (42%), Gaps = 29/299 (9%)
Frame = -1
Query: 980 ENATAGAVAGFATVAAMHPLDVVRTRFQVNDGRGLSALPTYKNTAHALFTIARLEGLRGG 801
++ AG++ G V HPLD ++ R Q P Y T L EG G
Sbjct: 15 KDIVAGSIGGVGQVFTGHPLDTIKVRLQTQS----VGNPIYSGTMDCLKKTISQEGF-AG 69
Query: 800 LYAGFFPAVIGSTLSWSLYFFFYGRAKQRYGRGRDDDKLTPPLHLASAAEAGALT----- 636
LY G ++G ++ S+ F YG++K + D+ L L AGAL
Sbjct: 70 LYKGVASPLVGLSIMNSVMFLAYGQSKTLIQKLSDNP--NEALDLKGLTAAGALAGIAIG 127
Query: 635 ---------RLQLQTPLHQTPPYSGLLDAFRTIIKEEGPRALYKGILPALLL-VSHGAIQ 486
+ Q+Q Y D + I K G R +++G+ L+ + A
Sbjct: 128 FVDAPVDLFKSQMQVQQGDKNQYKSTADCAKQIWKVGGVRGVFQGLGATLVRDIPANACY 187
Query: 485 FTAYEELRKLIVDFKDKRRNSESTSDNLLNSADYAALGDSSKVATVLLTYPFQVIRARLQ 306
F AYE R + + ++ S N L+S A G + V+ LTYP V+++ +Q
Sbjct: 188 FGAYELCRDFLA-------SKDNISVNQLSSLQIMAAGGAGGVSYWTLTYPADVVKSTMQ 240
Query: 305 QRPSTNGVPRYIDSLHVIRETARFEGVRGFYRGLTANLLKNVPASSITFIVYENVLKLL 129
+Y + + + + +G+ GFY+G T +++VPA++ F++YE +++
Sbjct: 241 TDAIVKSQRKYKNMIDCASKIYKQQGIAGFYKGFTPCFIRSVPANAACFVLYEKARQIM 299
>sp|Q9P6L7|YKQ9_SCHPO Uncharacterized mitochondrial carrier C688.09
OS=Schizosaccharomyces pombe GN=SPAC688.09 PE=2 SV=1
Length = 361
Score = 91 bits (225), Expect = 1e-017
Identities = 55/173 (31%), Positives = 86/173 (49%), Gaps = 3/173 (1%)
Frame = -1
Query: 638 TRLQLQTPLHQTPPYSGLLDAFRTIIKEEGPRALYKGILPALLLVSHGAIQFTAYEELRK 459
TRLQL Q Y +D I+ EG R LYKG+ +LL V +Q+ YE+ +
Sbjct: 188 TRLQLDKKSGQAAQYRSSIDCIIKTIRLEGFRGLYKGLSASLLGVGESTLQWVLYEKFKH 247
Query: 458 LIVDFKDKRRN---SESTSDNLLNSADYAALGDSSKVATVLLTYPFQVIRARLQQRPSTN 288
+ + +R+ E+ D +L+ +K + YP +V+R RL+Q PS N
Sbjct: 248 AVAIRQLRRKELGIQETIYDKVLDWGGKLGGAGIAKFMAAGIAYPHEVVRTRLRQSPSIN 307
Query: 287 GVPRYIDSLHVIRETARFEGVRGFYRGLTANLLKNVPASSITFIVYENVLKLL 129
G P+Y + + +G+ G Y GLTA+LL+ VP + I F YE ++ +
Sbjct: 308 GTPKYTGLIQCFKLVWMEQGIVGLYGGLTAHLLRVVPNACILFGSYEVIMHFI 360
>sp|A6RF73|TPC1_AJECN Mitochondrial thiamine pyrophosphate carrier 1
OS=Ajellomyces capsulata (strain NAm1 / WU24) GN=TPC1 PE=3 SV=1
Length = 324
Score = 86 bits (210), Expect = 6e-016
Identities = 91/311 (29%), Positives = 125/311 (40%), Gaps = 51/311 (16%)
Frame = -1
Query: 968 AGAVAGFATVAAMHPLDVVRTRFQV-----------NDGRGLSALPTYKNTAHALFTIAR 822
AGA AG + + PLDVV+ R Q+ D +G P YK T L +I R
Sbjct: 20 AGATAGLVSRFCVAPLDVVKIRLQLQIHSLSDPLSHRDIKG----PIYKGTISTLKSIFR 75
Query: 821 LEGLRGGLYAGFFPAVIGSTLSWSLYFFFYGRAKQRYGRGRDDDKLTPPLHLASAAEAGA 642
EG+ GL+ G PA + + F Y RA R P S A AG
Sbjct: 76 DEGIT-GLWKGNIPAELLYICYGGIQFSSY-RAISSALRTLPHPLPQPVESFISGAVAGG 133
Query: 641 L------------TRLQLQTPLHQTPPYSGLLDAFRTIIKEEGPRALYKGILPALL-LVS 501
+ TR Q Y+ L + R I + EGP ++G A+ +V
Sbjct: 134 IATTSTYPLDLLRTRFAAQ---GNDRIYASLRVSVRDIARTEGPHGFFRGATAAIAQIVP 190
Query: 500 HGAIQFTAYEELRKLIVDFKDKRRNSESTSDNLLNSADYAALGDSSKVATVLLTYPFQVI 321
+ + F YE LR I + L A G + V +P ++
Sbjct: 191 YMGLFFAGYEALRSPIASLE------------LPFGTGDAGAGVVASVIAKTGVFPLDLV 238
Query: 320 RARLQQRPST------NGVPRYIDSLHVIRETARFEGVRGFYRGLTANLLKNVPASSITF 159
R RLQ + T +P Y IR +G +G YRGLT +L+K PAS++T
Sbjct: 239 RKRLQVQGPTRRRYIHTNIPVYEGVYRTIRAILASQGPKGLYRGLTVSLIKAAPASAVTM 298
Query: 158 IVYENVLKLLK 126
YE+VL LLK
Sbjct: 299 WTYEHVLGLLK 309
>sp|O43808|PM34_HUMAN Peroxisomal membrane protein PMP34 OS=Homo sapiens
GN=SLC25A17 PE=1 SV=1
Length = 307
Score = 80 bits (195), Expect = 3e-014
Identities = 61/187 (32%), Positives = 95/187 (50%), Gaps = 18/187 (9%)
Frame = -1
Query: 686 LTPPLHLASAAEAGALTRLQLQTPLHQTPP-----YSGLLDAFRTIIKEEGPRALYKGIL 522
LT PL + + TRL+LQ + Y G++DAF II++EG AL+ G
Sbjct: 118 LTTPLWVVN-------TRLKLQGAKFRNEDIVPTNYKGIIDAFHQIIRDEGISALWNGTF 170
Query: 521 PALLLVSHGAIQFTAYEELRKLIVDFKDKRRNSESTSDNLLNSADYAALGDSSKVATVLL 342
P+LLLV + AIQF YE L++ ++ K+R S+ D + A A+ + +
Sbjct: 171 PSLLLVFNPAIQFMFYEGLKRQLL----KKRMKLSSLDVFIIGAVAKAIATTVTYPLQTV 226
Query: 341 TYPFQVIRARLQQRPSTNGVPRYIDSLHVIRETARFEGVRGFYRGLTANLLKNVPASSIT 162
+ R RL T G R I L+++ + R G+ G Y+GL A LL+ V +++
Sbjct: 227 QSILRFGRHRLNPENRTLGSLRNI--LYLLHQRVRRFGIMGLYKGLEAKLLQTVLTAALM 284
Query: 161 FIVYENV 141
F+VYE +
Sbjct: 285 FLVYEKL 291
>sp|Q4X022|TPC1_ASPFU Mitochondrial thiamine pyrophosphate carrier 1
OS=Aspergillus fumigatus GN=tpc1 PE=3 SV=3
Length = 317
Score = 79 bits (193), Expect = 5e-014
Identities = 54/164 (32%), Positives = 79/164 (48%), Gaps = 18/164 (10%)
Frame = -1
Query: 596 YSGLLDAFRTIIKEEGPRALYKGILPAL-LLVSHGAIQFTAYEELRKLIVDFKDKRRNSE 420
Y+ LL + R I + EGP ++G A+ +V + + F YE LR ++
Sbjct: 159 YTSLLASVRDIARSEGPAGFFRGCSAAVGQIVPYMGLFFATYESLRPVL----------- 207
Query: 419 STSDNLLNSADYAALGDSSKVATVLLTYPFQVIRARLQQRPST------NGVPRYIDSLH 258
S +N+ + AA G + V +P ++R RLQ + T +P Y
Sbjct: 208 SGLENMPFGSGDAAAGVIASVLAKSGVFPLDLVRKRLQVQGPTRTLYVHRNIPEYRGVFS 267
Query: 257 VIRETARFEGVRGFYRGLTANLLKNVPASSITFIVYENVLKLLK 126
I R +GVRG YRGLT +L+K PAS+IT YE LKLL+
Sbjct: 268 TIAMIVRTQGVRGLYRGLTVSLIKAAPASAITMWTYERSLKLLR 311
>sp|A1DI57|TPC1_NEOFI Mitochondrial thiamine pyrophosphate carrier 1
OS=Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 /
NRRL 181) GN=tpc1 PE=3 SV=1
Length = 317
Score = 77 bits (188), Expect = 2e-013
Identities = 53/163 (32%), Positives = 78/163 (47%), Gaps = 18/163 (11%)
Frame = -1
Query: 596 YSGLLDAFRTIIKEEGPRALYKGILPAL-LLVSHGAIQFTAYEELRKLIVDFKDKRRNSE 420
Y+ LL + + I + EGP ++G A+ +V + + F YE LR ++
Sbjct: 159 YTSLLASVQDIARNEGPAGFFRGCSAAVGQIVPYMGLFFATYESLRPVL----------- 207
Query: 419 STSDNLLNSADYAALGDSSKVATVLLTYPFQVIRARLQQRPST------NGVPRYIDSLH 258
S +N+ + AA G + V +P ++R RLQ + T +P Y
Sbjct: 208 SGLENMPFGSGDAAAGVIASVLAKTGVFPLDLVRKRLQVQGPTRTLYVHRNIPEYRGVFS 267
Query: 257 VIRETARFEGVRGFYRGLTANLLKNVPASSITFIVYENVLKLL 129
I R +GVRG YRGLT +L+K PAS+IT YE LKLL
Sbjct: 268 TIAMIVRTQGVRGLYRGLTVSLIKAAPASAITMWTYERSLKLL 310
>sp|O70579|PM34_MOUSE Peroxisomal membrane protein PMP34 OS=Mus musculus
GN=Slc25a17 PE=2 SV=1
Length = 307
Score = 77 bits (187), Expect = 3e-013
Identities = 59/187 (31%), Positives = 94/187 (50%), Gaps = 18/187 (9%)
Frame = -1
Query: 686 LTPPLHLASAAEAGALTRLQLQTPLHQTPP-----YSGLLDAFRTIIKEEGPRALYKGIL 522
LT PL + + TRL+LQ + Y G++DAF II++EG AL+ G
Sbjct: 118 LTTPLWVVN-------TRLKLQGAKFRNEDIIPTNYKGIIDAFHQIIRDEGILALWNGTF 170
Query: 521 PALLLVSHGAIQFTAYEELRKLIVDFKDKRRNSESTSDNLLNSADYAALGDSSKVATVLL 342
P+LLLV + AIQF YE L++ ++ K+R S+ D + A A+ + +
Sbjct: 171 PSLLLVFNPAIQFMFYEGLKRQLL----KKRMKLSSLDVFIIGAIAKAIATTVTYPMQTV 226
Query: 341 TYPFQVIRARLQQRPSTNGVPRYIDSLHVIRETARFEGVRGFYRGLTANLLKNVPASSIT 162
+ R RL T G R + L ++ + + G+ G Y+GL A LL+ V +++
Sbjct: 227 QSILRFGRHRLNPENRTLGSLRNV--LSLLHQRVKRFGIMGLYKGLEAKLLQTVLTAALM 284
Query: 161 FIVYENV 141
F+VYE +
Sbjct: 285 FLVYEKL 291
>sp|B0G159|MCFC_DICDI Mitochondrial substrate carrier family protein C
OS=Dictyostelium discoideum GN=mcfC PE=2 SV=1
Length = 472
Score = 75 bits (183), Expect = 8e-013
Identities = 58/235 (24%), Positives = 106/235 (45%), Gaps = 25/235 (10%)
Frame = -1
Query: 803 GLYAGFFPAVIGSTLSWSLYFFFYGRAKQRYGRGRDDDKLTPPLHLASAAEAGALT---- 636
G + G +I + ++ F Y K+ + +D +LT S + AG ++
Sbjct: 239 GFFRGNLANIIKVSPESAVKFGTYEYVKKLF--AENDCELTSAQRFISGSVAGVVSHTTL 296
Query: 635 ------RLQLQTPLHQTPPYSGLLDAFRTI-IKEEGPRALYKGILPAL-LLVSHGAIQFT 480
RL+L + T Y+G+ D F+ I I E+ R Y+G+ ++ + H +
Sbjct: 297 FPLEVVRLRLSAEIAGT--YNGIFDCFKKIAISEKSIRPFYRGLGASITATIPHSGVNMM 354
Query: 479 AYEELRKLIVDFKDKRRNSESTSDNLLNSADYAALGDSSKVATVLLTYPFQVIRARLQQR 300
YE L+ ++ + T + + +S V L+ YPF V+++RL +
Sbjct: 355 VYEFLKHKVI---------KMTGNEFPTAGQLLVCASTSSVCGQLVGYPFHVVKSRLITQ 405
Query: 299 PSTNGVPRYIDSLHVIRETARFEGVRGFYRGLTANLLKNVPASSITFIVYENVLK 135
S+ +Y + + + EG G Y+G+ + +K++P+ SITFIVYE K
Sbjct: 406 GSSVNQEKYTGLFDGLTKIIKKEGPIGLYKGIVPSFMKSIPSHSITFIVYEGFKK 460
>sp|A2R5A0|TPC1_ASPNC Mitochondrial thiamine pyrophosphate carrier 1
OS=Aspergillus niger (strain CBS 513.88 / FGSC A1513) GN=tpc1 PE=3
SV=1
Length = 321
Score = 75 bits (183), Expect = 8e-013
Identities = 49/164 (29%), Positives = 81/164 (49%), Gaps = 18/164 (10%)
Frame = -1
Query: 596 YSGLLDAFRTIIKEEGPRALYKGILPAL-LLVSHGAIQFTAYEELRKLIVDFKDKRRNSE 420
Y+ L+ + R I + EG ++G A+ +V + + F YE LR + ++D
Sbjct: 159 YTSLMSSVRDIARNEGYAGFFRGCSAAVGQIVPYMGLFFATYEALRPPLAQYQD------ 212
Query: 419 STSDNLLNSADYAALGDSSKVATVLLTYPFQVIRARLQQRPST------NGVPRYIDSLH 258
L + AA G + V++ + +P +IR RLQ + T +P Y +
Sbjct: 213 -----LPFGSGDAAAGVIASVSSKTVMFPLDLIRKRLQVQGPTRQLYIHRNIPEYQGVFN 267
Query: 257 VIRETARFEGVRGFYRGLTANLLKNVPASSITFIVYENVLKLLK 126
++ R +G+RG YRGLT +L K PAS++T YE L+LL+
Sbjct: 268 TMKLILRTQGIRGLYRGLTVSLFKAAPASAVTMWTYETSLRLLQ 311
>sp|A4RF23|TPC1_MAGGR Mitochondrial thiamine pyrophosphate carrier 1
OS=Magnaporthe grisea GN=TPC1 PE=3 SV=2
Length = 327
Score = 73 bits (177), Expect = 4e-012
Identities = 53/163 (32%), Positives = 77/163 (47%), Gaps = 18/163 (11%)
Frame = -1
Query: 596 YSGLLDAFRTIIKEEGPRALYKGILPAL-LLVSHGAIQFTAYEELRKLIVDFKDKRRNSE 420
Y L A I ++EG R ++GI PA+ I F AYE LR + D K +
Sbjct: 167 YQSLRRAVADIWRDEGYRGFFRGIGPAVGQTFPFMGIFFAAYESLRAPLADLKLPFWGGQ 226
Query: 419 STSDNLLNSADYAALGDSSKVATVLLTYPFQVIRARLQQRPST------NGVPRYIDSLH 258
A++ S+ T + +P ++R R+Q + T +P Y +
Sbjct: 227 LA---------LASMTASTLAKTAV--FPLDLVRRRIQVQGPTRSKYVHKNIPEYKGTFS 275
Query: 257 VIRETARFEGVRGFYRGLTANLLKNVPASSITFIVYENVLKLL 129
I AR EG RG YRGLT +L+K+ PAS++T YE VL+ L
Sbjct: 276 TISTIARTEGFRGLYRGLTVSLIKSAPASAVTMWTYERVLRAL 318
>sp|A6SL61|TPC1_BOTFB Mitochondrial thiamine pyrophosphate carrier 1
OS=Botryotinia fuckeliana (strain B05.10) GN=tpc1 PE=3 SV=1
Length = 322
Score = 72 bits (176), Expect = 5e-012
Identities = 54/163 (33%), Positives = 76/163 (46%), Gaps = 19/163 (11%)
Frame = -1
Query: 596 YSGLLDAFRTIIKEEGPRALYKGILPAL-LLVSHGAIQFTAYEELRKLIVDFKDKRRNSE 420
Y+ L + R I EGPR ++G+ + +V + I F YE LR +
Sbjct: 161 YTSLRSSIRDIAISEGPRGFFQGLGAGVGQIVPYMGIFFATYESLRLPM----------- 209
Query: 419 STSDNLLNSADYAALGDSSKVATVLLTYPFQVIRARLQQRPST------NGVPRYIDSLH 258
T + SAD A+ G + V +PF +IR RLQ + T +P Y
Sbjct: 210 GTLNMPFGSAD-ASAGVIASVIAKTGIFPFDLIRKRLQVQGPTRERYVHKNIPVYNGVFQ 268
Query: 257 VIRETARFEGVRGFYRGLTANLLKNVPASSITFIVYENVLKLL 129
+R EG RG YRGLT +L K+ PAS++T YE VL +L
Sbjct: 269 TMRHILHNEGYRGLYRGLTVSLFKSAPASAVTMWTYERVLGIL 311
>sp|O94502|YBT5_SCHPO Uncharacterized mitochondrial carrier C12D12.05c
OS=Schizosaccharomyces pombe GN=SPBC12D12.05c PE=2 SV=2
Length = 426
Score = 71 bits (172), Expect = 1e-011
Identities = 46/154 (29%), Positives = 74/154 (48%), Gaps = 2/154 (1%)
Frame = -1
Query: 587 LLDAFRTIIKEEGPRALYKGILPALL-LVSHGAIQFTAYEELRKLIVDFKDKRRNSESTS 411
+L + + K G R Y+G+L +L + + A +E L++ + R N +
Sbjct: 271 ILSNAKELYKSVGIRGYYRGVLVGILGMFPYSATDLGTFEGLKRTWIGILASRDNVDPQD 330
Query: 410 DNLLNSADYAALGDSSKVATVLLTYPFQVIRARLQQRPSTNGVPRYIDSLHVIRETARFE 231
L N A G S + +P VIR RLQ + ++ Y + +T + E
Sbjct: 331 VKLPNGL-VMAFGALSGSTGATIVFPLNVIRTRLQTQGTSAHPATYDGFIDCFYKTTKNE 389
Query: 230 GVRGFYRGLTANLLKNVPASSITFIVYENVLKLL 129
G RG Y+GL+ NLLK P+ +I+++VYEN K L
Sbjct: 390 GFRGLYKGLSPNLLKVAPSVAISYLVYENCKKWL 423
>sp|A7ER02|TPC1_SCLS1 Mitochondrial thiamine pyrophosphate carrier 1
OS=Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) GN=tpc1
PE=3 SV=1
Length = 322
Score = 70 bits (171), Expect = 2e-011
Identities = 53/163 (32%), Positives = 74/163 (45%), Gaps = 19/163 (11%)
Frame = -1
Query: 596 YSGLLDAFRTIIKEEGPRALYKGILPAL-LLVSHGAIQFTAYEELRKLIVDFKDKRRNSE 420
Y+ L + R I EGPR ++G+ + ++ + I F YE LR +
Sbjct: 161 YTSLRASIRDIAVNEGPRGFFQGLGAGVGQIIPYMGIFFATYETLRVPL----------- 209
Query: 419 STSDNLLNSADYAALGDSSKVATVLLTYPFQVIRARLQQRPST------NGVPRYIDSLH 258
T S D A G + V +PF +IR RLQ + T +P Y
Sbjct: 210 GTLHMPFGSGD-ATAGVLASVIAKTGIFPFDLIRKRLQVQGPTRERYVHKNIPVYNGVFR 268
Query: 257 VIRETARFEGVRGFYRGLTANLLKNVPASSITFIVYENVLKLL 129
+R + EG RG YRGLT +L K PAS++T YE VL+LL
Sbjct: 269 TMRHIIQNEGYRGLYRGLTVSLFKAAPASAVTMWTYERVLRLL 311
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 133,255,942,245
Number of Sequences: 518415
Number of Extensions: 133255942245
Number of Successful Extensions: 824475253
Number of sequences better than 0.0: 0
|
