BLASTX 7.6.2
Query= UN35118 /QuerySize=1392
(1391 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9SU08|AUXI1_ARATH Auxilin-related protein 1 OS=Arabidopsis t... 224 2e-057
sp|Q0WQ57|AUXI2_ARATH Auxilin-related protein 2 OS=Arabidopsis t... 223 3e-057
sp|O13773|UCP7_SCHPO UBA domain-containing protein 7 OS=Schizosa... 98 1e-019
sp|Q80TZ3|AUXI_MOUSE Putative tyrosine-protein phosphatase auxil... 82 1e-014
sp|Q27974|AUXI_BOVIN Putative tyrosine-protein phosphatase auxil... 81 2e-014
sp|O75061|AUXI_HUMAN Putative tyrosine-protein phosphatase auxil... 81 2e-014
sp|Q99KY4|GAK_MOUSE Cyclin-G-associated kinase OS=Mus musculus G... 78 1e-013
sp|P97874|GAK_RAT Cyclin-G-associated kinase OS=Rattus norvegicu... 78 1e-013
sp|O14976|GAK_HUMAN Cyclin-G-associated kinase OS=Homo sapiens G... 72 1e-011
sp|Q06677|SWA2_YEAST Auxilin-like clathrin uncoating factor SWA2... 70 4e-011
>sp|Q9SU08|AUXI1_ARATH Auxilin-related protein 1 OS=Arabidopsis thaliana
GN=At4g12780 PE=1 SV=2
Length = 904
Score = 224 bits (569), Expect = 2e-057
Identities = 110/174 (63%), Positives = 136/174 (78%), Gaps = 1/174 (0%)
Frame = +3
Query: 561 KKPPSPANLVDDFSALFGEDPIFK-EFEEIPGETEERRKAGWDREQRTKSRVAQAVADMN 737
+K S N+VDD S++FG F+++ GETEERR+A +R QRT+ R A+A+A+ N
Sbjct: 730 RKTSSVTNIVDDLSSIFGASASQSGGFQDVDGETEERRRARLERHQRTQERAAKALAEKN 789
Query: 738 NRDHQSRIEQEQRTRISESADAEIKRWATGKEGNMRALLSSLQIVLWPGCGWEAVSLTDL 917
RD Q + EQ ++ RI + D EIKRW GKEGN+RALLS+LQ VLWP CGW+ VSLTDL
Sbjct: 790 ERDLQVQREQVEKDRIGVTLDVEIKRWGAGKEGNLRALLSTLQYVLWPECGWQPVSLTDL 849
Query: 918 ITSSAVKKVYRKATLYVHPDKVQQKGATLEQKYIAEKVFDILKEAWNKFNKEEL 1079
IT+++VKKVYRKATL +HPDKVQQKGA L+QKYIAEKVFD+LKEAWNKFN EEL
Sbjct: 850 ITAASVKKVYRKATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKFNSEEL 903
>sp|Q0WQ57|AUXI2_ARATH Auxilin-related protein 2 OS=Arabidopsis thaliana
GN=At4g12770 PE=1 SV=1
Length = 891
Score = 223 bits (567), Expect = 3e-057
Identities = 110/175 (62%), Positives = 137/175 (78%), Gaps = 3/175 (1%)
Frame = +3
Query: 561 KKPPSPANLVDDFSALFGEDPIFKE--FEEIPGETEERRKAGWDREQRTKSRVAQAVADM 734
+K S N+VDD S++FG P + F+++ GETEERR+A +R QRT+ R A+A+A+
Sbjct: 717 RKASSATNIVDDLSSIFGA-PASQSGGFQDVDGETEERRRARLERHQRTQERAAKALAEK 775
Query: 735 NNRDHQSRIEQEQRTRISESADAEIKRWATGKEGNMRALLSSLQIVLWPGCGWEAVSLTD 914
N RD Q + EQ ++ RI + D EI+RW GKEGN+RALLS+LQ VLWP CGW+ VSLTD
Sbjct: 776 NERDLQVQREQAEKDRIGGTLDVEIRRWGAGKEGNLRALLSTLQYVLWPECGWQPVSLTD 835
Query: 915 LITSSAVKKVYRKATLYVHPDKVQQKGATLEQKYIAEKVFDILKEAWNKFNKEEL 1079
LIT ++VKKVYRKATL +HPDKVQQKGA L+QKYIAEKVFD+LKEAWNKFN EEL
Sbjct: 836 LITGASVKKVYRKATLCIHPDKVQQKGANLQQKYIAEKVFDMLKEAWNKFNSEEL 890
>sp|O13773|UCP7_SCHPO UBA domain-containing protein 7 OS=Schizosaccharomyces
pombe GN=ucp7 PE=2 SV=1
Length = 697
Score = 98 bits (243), Expect = 1e-019
Identities = 48/110 (43%), Positives = 68/110 (61%), Gaps = 3/110 (2%)
Frame = +3
Query: 750 QSRIEQ--EQRTRISESADAEIKRWATGKEGNMRALLSSLQIVLWPGCGWEAVSLTDLIT 923
Q + EQ E+R+R+ E + +W GKE N+RALL+SL +LWP C W+ VSL++L+
Sbjct: 586 QQKAEQLDEERSRLREPVQQIVNKWKEGKESNLRALLASLDTILWPECRWQKVSLSELVL 645
Query: 924 SSAVKKVYRKATLYVHPDKVQQKGATLEQKYIAEKVFDILKEAWNKFNKE 1073
VK Y KA VHPDK+ Q+ ++E + IAE F IL AW F ++
Sbjct: 646 PKKVKIAYMKAVSRVHPDKLPQQ-TSVEHQLIAESAFSILNHAWELFKQQ 694
>sp|Q80TZ3|AUXI_MOUSE Putative tyrosine-protein phosphatase auxilin OS=Mus
musculus GN=Dnajc6 PE=2 SV=2
Length = 938
Score = 82 bits (200), Expect = 1e-014
Identities = 61/190 (32%), Positives = 93/190 (48%), Gaps = 8/190 (4%)
Frame = +3
Query: 510 KPAVNVTKKTTNGVSSAKKPPSPANLVDDFSALFGEDPIFKEFEEIPGETE-ERRKAGWD 686
+PA ++T + S+ SP N +++ F P + E G T E ++ D
Sbjct: 749 QPAGYNWQQTQSKPQSSMPHSSPQNR-PNYNVSFSAMPA-GQSERGKGSTNLEGKQKAAD 806
Query: 687 REQRTKSRVAQAVADMNNRDHQSRIEQEQRTRISESADAEIKRWATGKEGNMRALLSSLQ 866
E S+ A D + + +E+ + + +I W GKE N+RALLS++
Sbjct: 807 FEDLLSSQGFNAHKDKKGPRTIAEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMH 866
Query: 867 IVLWPG-CGWEAVSLTDLITSSAVKKVYRKATLYVHPDKVQQKGATLEQKYIAEKVFDIL 1043
VLW G W+ V + DL+T VKKVYR+A L VHPDK G EQ A+ +F L
Sbjct: 867 TVLWAGETKWKPVGMADLVTPEQVKKVYRRAVLVVHPDKA--TGQPYEQ--YAKMIFMEL 922
Query: 1044 KEAWNKFNKE 1073
+AW++F +
Sbjct: 923 NDAWSEFENQ 932
>sp|Q27974|AUXI_BOVIN Putative tyrosine-protein phosphatase auxilin OS=Bos
taurus GN=DNAJC6 PE=1 SV=1
Length = 910
Score = 81 bits (198), Expect = 2e-014
Identities = 44/108 (40%), Positives = 63/108 (58%), Gaps = 5/108 (4%)
Frame = +3
Query: 753 SRIEQEQRTRISESADAEIKRWATGKEGNMRALLSSLQIVLWPG-CGWEAVSLTDLITSS 929
+ + +E+ + + +I W GKE N+RALLS++ VLW G W+ V + DL+T
Sbjct: 801 AEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTPE 860
Query: 930 AVKKVYRKATLYVHPDKVQQKGATLEQKYIAEKVFDILKEAWNKFNKE 1073
VKKVYRKA L VHPDK G EQ A+ +F L +AW++F +
Sbjct: 861 QVKKVYRKAVLVVHPDKA--TGQPYEQ--YAKMIFMELNDAWSEFENQ 904
>sp|O75061|AUXI_HUMAN Putative tyrosine-protein phosphatase auxilin OS=Homo
sapiens GN=DNAJC6 PE=1 SV=3
Length = 913
Score = 81 bits (198), Expect = 2e-014
Identities = 44/108 (40%), Positives = 63/108 (58%), Gaps = 5/108 (4%)
Frame = +3
Query: 753 SRIEQEQRTRISESADAEIKRWATGKEGNMRALLSSLQIVLWPG-CGWEAVSLTDLITSS 929
+ + +E+ + + +I W GKE N+RALLS++ VLW G W+ V + DL+T
Sbjct: 804 AEMRKEEMAKEMDPEKLKILEWIEGKERNIRALLSTMHTVLWAGETKWKPVGMADLVTPE 863
Query: 930 AVKKVYRKATLYVHPDKVQQKGATLEQKYIAEKVFDILKEAWNKFNKE 1073
VKKVYRKA L VHPDK G EQ A+ +F L +AW++F +
Sbjct: 864 QVKKVYRKAVLVVHPDKA--TGQPYEQ--YAKMIFMELNDAWSEFENQ 907
>sp|Q99KY4|GAK_MOUSE Cyclin-G-associated kinase OS=Mus musculus GN=Gak PE=1
SV=2
Length = 1305
Score = 78 bits (191), Expect = 1e-013
Identities = 44/117 (37%), Positives = 65/117 (55%), Gaps = 5/117 (4%)
Frame = +3
Query: 726 ADMNNRDHQSRIEQEQRTRISESADAEIKRWATGKEGNMRALLSSLQIVLWPG-CGWEAV 902
+D + + +++ R ++ ++ W GKE N+RALLS+L VLW G W V
Sbjct: 1187 SDKKGPKTMAEMRKQELARDTDPLKLKLLDWIEGKERNIRALLSTLHTVLWDGESRWTPV 1246
Query: 903 SLTDLITSSAVKKVYRKATLYVHPDKVQQKGATLEQKYIAEKVFDILKEAWNKFNKE 1073
S+ DL+T VKK YR+A L VHPDK G EQ A+ +F L +AW++F +
Sbjct: 1247 SMADLVTPEQVKKQYRRAVLVVHPDKA--TGQPYEQ--YAKMIFMELNDAWSEFENQ 1299
>sp|P97874|GAK_RAT Cyclin-G-associated kinase OS=Rattus norvegicus GN=Gak PE=2
SV=1
Length = 1305
Score = 78 bits (191), Expect = 1e-013
Identities = 44/117 (37%), Positives = 65/117 (55%), Gaps = 5/117 (4%)
Frame = +3
Query: 726 ADMNNRDHQSRIEQEQRTRISESADAEIKRWATGKEGNMRALLSSLQIVLWPG-CGWEAV 902
+D + + +++ R ++ ++ W GKE N+RALLS+L VLW G W V
Sbjct: 1187 SDKKGPKTMAEMRKQELARDTDPFKLKLLDWIEGKERNIRALLSTLHTVLWDGESRWTPV 1246
Query: 903 SLTDLITSSAVKKVYRKATLYVHPDKVQQKGATLEQKYIAEKVFDILKEAWNKFNKE 1073
S+ DL+T VKK YR+A L VHPDK G EQ A+ +F L +AW++F +
Sbjct: 1247 SMADLVTPEQVKKQYRRAVLVVHPDKA--TGQPYEQS--AKMIFMELNDAWSEFENQ 1299
>sp|O14976|GAK_HUMAN Cyclin-G-associated kinase OS=Homo sapiens GN=GAK PE=1
SV=2
Length = 1311
Score = 72 bits (174), Expect = 1e-011
Identities = 40/87 (45%), Positives = 51/87 (58%), Gaps = 5/87 (5%)
Frame = +3
Query: 816 WATGKEGNMRALLSSLQIVLWPG-CGWEAVSLTDLITSSAVKKVYRKATLYVHPDKVQQK 992
W GKE N+RALLS+L VLW G W V + DL+ VKK YR+A L VHPDK
Sbjct: 1223 WIEGKERNIRALLSTLHTVLWDGESRWTPVGMADLVAPEQVKKHYRRAVLAVHPDKA--A 1280
Query: 993 GATLEQKYIAEKVFDILKEAWNKFNKE 1073
G EQ A+ +F L +AW++F +
Sbjct: 1281 GQPYEQH--AKMIFMELNDAWSEFENQ 1305
>sp|Q06677|SWA2_YEAST Auxilin-like clathrin uncoating factor SWA2
OS=Saccharomyces cerevisiae GN=SWA2 PE=1 SV=1
Length = 668
Score = 70 bits (169), Expect = 4e-011
Identities = 37/88 (42%), Positives = 52/88 (59%), Gaps = 4/88 (4%)
Frame = +3
Query: 804 EIKRWATGKEGNMRALLSSLQIVL-WPGCGWEAVSLTDLITSSAVKKVYRKATLYVHPDK 980
+I W GK+ ++R LL++L +L W C W+ VS+ DL+ VK Y KA HPDK
Sbjct: 577 KISSWKDGKDDDIRHLLANLSSLLTW--CNWKDVSMQDLVMPKRVKITYMKAVAKTHPDK 634
Query: 981 VQQKGATLEQKYIAEKVFDILKEAWNKF 1064
+ + +LE K IAE +F L AW+KF
Sbjct: 635 IPE-SLSLENKMIAENIFSTLSIAWDKF 661
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 137,588,346,264
Number of Sequences: 518415
Number of Extensions: 137588346264
Number of Successful Extensions: 853536757
Number of sequences better than 0.0: 0
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