BLASTX 7.6.2
Query= UN35570 /QuerySize=1357
(1356 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|A0QKN5|OTSB_MYCA1 Trehalose-phosphate phosphatase OS=Mycobact... 95 9e-019
sp|Q10850|Y2006_MYCTU Uncharacterized glycosyl hydrolase Rv2006/... 95 9e-019
sp|Q73U90|OTSB_MYCPA Trehalose-phosphate phosphatase OS=Mycobact... 95 1e-018
sp|B2HDP8|OTSB_MYCMM Trehalose-phosphate phosphatase OS=Mycobact... 93 3e-018
sp|A0PMI0|OTSB_MYCUA Trehalose-phosphate phosphatase OS=Mycobact... 92 8e-018
sp|Q7TWL7|OTSB_MYCBO Trehalose-phosphate phosphatase OS=Mycobact... 92 1e-017
sp|A1KP65|OTSB_MYCBP Trehalose-phosphate phosphatase OS=Mycobact... 92 1e-017
sp|A5U846|OTSB_MYCTA Trehalose-phosphate phosphatase OS=Mycobact... 92 1e-017
sp|O50401|OTSB_MYCTU Trehalose-phosphate phosphatase OS=Mycobact... 92 1e-017
sp|Q49734|OTSB_MYCLE Trehalose-phosphate phosphatase OS=Mycobact... 79 5e-014
>sp|A0QKN5|OTSB_MYCA1 Trehalose-phosphate phosphatase OS=Mycobacterium avium
(strain 104) GN=otsB PE=3 SV=1
Length = 391
Score = 95 bits (235), Expect = 9e-019
Identities = 56/162 (34%), Positives = 92/162 (56%), Gaps = 5/162 (3%)
Frame = -3
Query: 718 ATEFLPVISEVYMKLVEKTKSIQGAKVENNKFCASVHFRCVDENKWSDLAHLVRSVLKNY 539
A +PV+++ +L ++ +I G VE+ +F +VH+R ++ ++A VR+ +
Sbjct: 224 AAAAIPVLAQAAGRLSDELGTIPGVVVEHKRFGVAVHYRNAARDRVGEVAAAVRAA-GRH 282
Query: 538 PKLMLTQGRKVLEIRPIIKWDKGKALEFLLESLGYENCTDVFPIYIGDDRTDEDAFKILR 359
L +T GR+V+E+RP + WDKGK L +++E L + P+Y+GDD TDEDAF +R
Sbjct: 283 DALRVTTGREVIELRPDLDWDKGKTLHWVIEHLRRSGSGALTPVYLGDDITDEDAFDAVR 342
Query: 358 -DKRQGLGILV---SKYAKETNASYSLQEPDEVMDFLERLVE 245
QG+ ILV + T A ++L P +F ERL +
Sbjct: 343 GGPVQGVPILVRHNDDGDRATAALFALDSPARAAEFTERLAD 384
Score = 57 bits (136), Expect = 3e-007
Identities = 30/77 (38%), Positives = 41/77 (53%)
Frame = -1
Query: 996 GNQIVMFLDYDGTLSPIVDDPDRAFMSNKMRNTVRKLAMCFPTVIVSGRSREKVYNFVKL 817
G +F D+DGTLS IVDDPD A + +LA P ++SGR V V +
Sbjct: 139 GRHPAVFFDFDGTLSDIVDDPDAARPVAGATAALTRLAARCPVAVLSGRDLADVTKRVGV 198
Query: 816 TELCYAGSHGMDIKGPE 766
+ YAGSHG ++ P+
Sbjct: 199 PGIWYAGSHGFELTAPD 215
>sp|Q10850|Y2006_MYCTU Uncharacterized glycosyl hydrolase Rv2006/MT2062
OS=Mycobacterium tuberculosis GN=Rv2006 PE=1 SV=1
Length = 1327
Score = 95 bits (235), Expect = 9e-019
Identities = 62/159 (38%), Positives = 95/159 (59%), Gaps = 4/159 (2%)
Frame = -3
Query: 718 ATEFLPVISEVYMKLVEKTKSIQGAKVENNKFCASVHFRCVDENKWSDLAHLVRSVLKNY 539
AT + ++E +L + + I GA VE+ +F +VH+R V ++ +L VR L +
Sbjct: 364 ATAAIDGLAEAAAQLADALREIAGAVVEHKRFAVAVHYRNVADDSVDNLIAAVRR-LGHA 422
Query: 538 PKLMLTQGRKVLEIRPIIKWDKGKALEFLLESLG-YENCTDV-FPIYIGDDRTDEDAFKI 365
L +T GRKV+E+RP I WDKGKAL+++ E LG E D+ PIYIGDD TDEDAF
Sbjct: 423 AGLRVTTGRKVVELRPDIAWDKGKALDWIGERLGPAEVGPDLRLPIYIGDDLTDEDAFDA 482
Query: 364 LRDKRQGLGILVSKYA-KETNASYSLQEPDEVMDFLERL 251
+R G+ + +++ + + A++ L+ P V FL +L
Sbjct: 483 VRFTGVGIVVRHNEHGDRRSAATFRLECPYTVCQFLSQL 521
Score = 69 bits (166), Expect = 9e-011
Identities = 34/92 (36%), Positives = 53/92 (57%)
Frame = -1
Query: 1041 PSALNMFEEILHISEGNQIVMFLDYDGTLSPIVDDPDRAFMSNKMRNTVRKLAMCFPTVI 862
P AL ++ ++ + G + +FLD+DGTLS IV+ P+ A + + +R LA P +
Sbjct: 264 PDALQVYSQLKRLLTGRRPAVFLDFDGTLSDIVERPEAATLVDGAAEALRALAAQCPVAV 323
Query: 861 VSGRSREKVYNFVKLTELCYAGSHGMDIKGPE 766
+SGR V N VK+ L AGSHG ++ P+
Sbjct: 324 ISGRDLADVRNRVKVDGLWLAGSHGFELVAPD 355
>sp|Q73U90|OTSB_MYCPA Trehalose-phosphate phosphatase OS=Mycobacterium
paratuberculosis GN=otsB PE=3 SV=1
Length = 391
Score = 95 bits (234), Expect = 1e-018
Identities = 56/162 (34%), Positives = 92/162 (56%), Gaps = 5/162 (3%)
Frame = -3
Query: 718 ATEFLPVISEVYMKLVEKTKSIQGAKVENNKFCASVHFRCVDENKWSDLAHLVRSVLKNY 539
A +PV+++ +L ++ +I G VE+ +F +VH+R ++ ++A VR+ +
Sbjct: 224 AAAAIPVLAQAAGRLRDELGAIPGVVVEHKRFGVAVHYRNAARDRVGEVAAAVRAA-GRH 282
Query: 538 PKLMLTQGRKVLEIRPIIKWDKGKALEFLLESLGYENCTDVFPIYIGDDRTDEDAFKILR 359
L +T GR+V+E+RP + WDKGK L +++E L + P+Y+GDD TDEDAF +R
Sbjct: 283 DALRVTTGREVIELRPDLDWDKGKTLHWVIEHLRRSGSGALTPVYLGDDITDEDAFDAVR 342
Query: 358 -DKRQGLGILV---SKYAKETNASYSLQEPDEVMDFLERLVE 245
QG+ ILV + T A ++L P +F ERL +
Sbjct: 343 GGPVQGVPILVRHNDDGDRATAALFALDSPARAAEFTERLAD 384
Score = 57 bits (136), Expect = 3e-007
Identities = 30/77 (38%), Positives = 41/77 (53%)
Frame = -1
Query: 996 GNQIVMFLDYDGTLSPIVDDPDRAFMSNKMRNTVRKLAMCFPTVIVSGRSREKVYNFVKL 817
G +F D+DGTLS IVDDPD A + +LA P ++SGR V V +
Sbjct: 139 GRHPAVFFDFDGTLSDIVDDPDAARPVAGATAALTRLAARCPVAVLSGRDLADVTKRVGV 198
Query: 816 TELCYAGSHGMDIKGPE 766
+ YAGSHG ++ P+
Sbjct: 199 LGIWYAGSHGFELTAPD 215
>sp|B2HDP8|OTSB_MYCMM Trehalose-phosphate phosphatase OS=Mycobacterium marinum
(strain ATCC BAA-535 / M) GN=otsB PE=3 SV=1
Length = 390
Score = 93 bits (230), Expect = 3e-018
Identities = 54/161 (33%), Positives = 91/161 (56%), Gaps = 6/161 (3%)
Frame = -3
Query: 724 QPATEFLPVISEVYMKLVEKTKSIQGAKVENNKFCASVHFRCVDENKWSDLAHLVRSVLK 545
+ A +PV+ + +L ++ SI G VE+ +F + H+R ++ ++A +VR+ +
Sbjct: 225 EAAAAAIPVLEQAAAQLRDRLGSIPGVMVEHKRFGVATHYRNAARDRVGEIAAVVRAAGQ 284
Query: 544 NYPKLMLTQGRKVLEIRPIIKWDKGKALEFLLESLGYENCTDVFPIYIGDDRTDEDAFKI 365
L +T GR+V+E+RP I WDKGK L ++++ L + + PIY+GDD TDEDAF
Sbjct: 285 R-DGLRVTTGREVIELRPDIDWDKGKTLRWVIDHLPDQRAAPLVPIYLGDDITDEDAFDA 343
Query: 364 LRDKRQGLGILVSKYA---KETNASYSLQEPDEVMDFLERL 251
+ G+ I+V + T A ++L+ P V +F RL
Sbjct: 344 VGP--NGVAIMVRHNEDGDRATAALFALESPARVAEFTGRL 382
Score = 59 bits (140), Expect = 1e-007
Identities = 31/72 (43%), Positives = 42/72 (58%)
Frame = -1
Query: 981 MFLDYDGTLSPIVDDPDRAFMSNKMRNTVRKLAMCFPTVIVSGRSREKVYNFVKLTELCY 802
+F D+DGTLS IVDDPD A + +++LA P I+SGR V V L + Y
Sbjct: 147 VFFDFDGTLSEIVDDPDAATPTAGAVAALQQLAAQCPVAILSGRDLADVSQRVGLPGIWY 206
Query: 801 AGSHGMDIKGPE 766
AGSHG ++ P+
Sbjct: 207 AGSHGFELTAPD 218
>sp|A0PMI0|OTSB_MYCUA Trehalose-phosphate phosphatase OS=Mycobacterium ulcerans
(strain Agy99) GN=otsB PE=3 SV=1
Length = 390
Score = 92 bits (227), Expect = 8e-018
Identities = 54/161 (33%), Positives = 89/161 (55%), Gaps = 6/161 (3%)
Frame = -3
Query: 724 QPATEFLPVISEVYMKLVEKTKSIQGAKVENNKFCASVHFRCVDENKWSDLAHLVRSVLK 545
+ A +PV+ + +L ++ SI G VE+ +F + H+R N+ +A +VR+ +
Sbjct: 225 EAAAAAIPVLEQAAAQLRDRLGSIPGVMVEHKRFGVATHYRNAARNRVGKIAAVVRAAGQ 284
Query: 544 NYPKLMLTQGRKVLEIRPIIKWDKGKALEFLLESLGYENCTDVFPIYIGDDRTDEDAFKI 365
L +T GR+V+E+ P I WDKGK L ++++ L + + PIY+GDD TDEDAF
Sbjct: 285 R-DGLRVTTGREVIELHPDIDWDKGKTLRWVIDHLPDQRAAPLVPIYLGDDITDEDAFDA 343
Query: 364 LRDKRQGLGILVSKYA---KETNASYSLQEPDEVMDFLERL 251
+ G+ I+V + T A ++L+ P V +F RL
Sbjct: 344 VGP--NGVAIMVRHNEDGDRATAALFALESPARVAEFTGRL 382
Score = 59 bits (140), Expect = 1e-007
Identities = 31/72 (43%), Positives = 42/72 (58%)
Frame = -1
Query: 981 MFLDYDGTLSPIVDDPDRAFMSNKMRNTVRKLAMCFPTVIVSGRSREKVYNFVKLTELCY 802
+F D+DGTLS IVDDPD A + +++LA P I+SGR V V L + Y
Sbjct: 147 VFFDFDGTLSEIVDDPDAATPTAGAVAALQQLAAQCPVAILSGRDLADVSQRVGLPGIWY 206
Query: 801 AGSHGMDIKGPE 766
AGSHG ++ P+
Sbjct: 207 AGSHGFELTAPD 218
>sp|Q7TWL7|OTSB_MYCBO Trehalose-phosphate phosphatase OS=Mycobacterium bovis
GN=otsB PE=3 SV=1
Length = 391
Score = 92 bits (226), Expect = 1e-017
Identities = 53/159 (33%), Positives = 90/159 (56%), Gaps = 6/159 (3%)
Frame = -3
Query: 718 ATEFLPVISEVYMKLVEKTKSIQGAKVENNKFCASVHFRCVDENKWSDLAHLVRSVLKNY 539
A +PV+ + +L ++ G VE+ +F +VH+R ++ ++A VR+ + +
Sbjct: 224 AAAAIPVLKQAAAELRQQLGPFPGVVVEHKRFGVAVHYRNAARDRVGEVAAAVRTAEQRH 283
Query: 538 PKLMLTQGRKVLEIRPIIKWDKGKALEFLLESLGYENCTDVFPIYIGDDRTDEDAFKILR 359
L +T GR+V+E+RP + WDKGK L ++L+ L + + PIY+GDD TDEDAF ++
Sbjct: 284 -ALRVTTGREVIELRPDVDWDKGKTLLWVLDHLPHSGSAPLVPIYLGDDITDEDAFDVVG 342
Query: 358 DKRQGLGILV---SKYAKETNASYSLQEPDEVMDFLERL 251
G+ I+V + T A ++L P V +F +RL
Sbjct: 343 P--HGVPIVVRHTDDGDRATAALFALDSPARVAEFTDRL 379
Score = 62 bits (150), Expect = 7e-009
Identities = 31/75 (41%), Positives = 45/75 (60%)
Frame = -1
Query: 990 QIVMFLDYDGTLSPIVDDPDRAFMSNKMRNTVRKLAMCFPTVIVSGRSREKVYNFVKLTE 811
Q +F D+DGTLS IV+DPD A+++ ++KLA P ++SGR V V L
Sbjct: 141 QPAVFFDFDGTLSDIVEDPDAAWLAPGALEALQKLAARCPIAVLSGRDLADVTQRVGLPG 200
Query: 810 LCYAGSHGMDIKGPE 766
+ YAGSHG ++ P+
Sbjct: 201 IWYAGSHGFELTAPD 215
>sp|A1KP65|OTSB_MYCBP Trehalose-phosphate phosphatase OS=Mycobacterium bovis
(strain BCG / Pasteur 1173P2) GN=otsB PE=3 SV=1
Length = 391
Score = 92 bits (226), Expect = 1e-017
Identities = 53/159 (33%), Positives = 90/159 (56%), Gaps = 6/159 (3%)
Frame = -3
Query: 718 ATEFLPVISEVYMKLVEKTKSIQGAKVENNKFCASVHFRCVDENKWSDLAHLVRSVLKNY 539
A +PV+ + +L ++ G VE+ +F +VH+R ++ ++A VR+ + +
Sbjct: 224 AAAAIPVLKQAAAELRQQLGPFPGVVVEHKRFGVAVHYRNAARDRVGEVAAAVRTAEQRH 283
Query: 538 PKLMLTQGRKVLEIRPIIKWDKGKALEFLLESLGYENCTDVFPIYIGDDRTDEDAFKILR 359
L +T GR+V+E+RP + WDKGK L ++L+ L + + PIY+GDD TDEDAF ++
Sbjct: 284 -ALRVTTGREVIELRPDVDWDKGKTLLWVLDHLPHSGSAPLVPIYLGDDITDEDAFDVVG 342
Query: 358 DKRQGLGILV---SKYAKETNASYSLQEPDEVMDFLERL 251
G+ I+V + T A ++L P V +F +RL
Sbjct: 343 P--HGVPIVVRHTDDGDRATAALFALDSPARVAEFTDRL 379
Score = 62 bits (150), Expect = 7e-009
Identities = 31/75 (41%), Positives = 45/75 (60%)
Frame = -1
Query: 990 QIVMFLDYDGTLSPIVDDPDRAFMSNKMRNTVRKLAMCFPTVIVSGRSREKVYNFVKLTE 811
Q +F D+DGTLS IV+DPD A+++ ++KLA P ++SGR V V L
Sbjct: 141 QPAVFFDFDGTLSDIVEDPDAAWLAPGALEALQKLAARCPIAVLSGRDLADVTQRVGLPG 200
Query: 810 LCYAGSHGMDIKGPE 766
+ YAGSHG ++ P+
Sbjct: 201 IWYAGSHGFELTAPD 215
>sp|A5U846|OTSB_MYCTA Trehalose-phosphate phosphatase OS=Mycobacterium
tuberculosis (strain ATCC 25177 / H37Ra) GN=otsB PE=3 SV=1
Length = 391
Score = 92 bits (226), Expect = 1e-017
Identities = 53/159 (33%), Positives = 90/159 (56%), Gaps = 6/159 (3%)
Frame = -3
Query: 718 ATEFLPVISEVYMKLVEKTKSIQGAKVENNKFCASVHFRCVDENKWSDLAHLVRSVLKNY 539
A +PV+ + +L ++ G VE+ +F +VH+R ++ ++A VR+ + +
Sbjct: 224 AAAAIPVLKQAAAELRQQLGPFPGVVVEHKRFGVAVHYRNAARDRVGEVAAAVRTAEQRH 283
Query: 538 PKLMLTQGRKVLEIRPIIKWDKGKALEFLLESLGYENCTDVFPIYIGDDRTDEDAFKILR 359
L +T GR+V+E+RP + WDKGK L ++L+ L + + PIY+GDD TDEDAF ++
Sbjct: 284 -ALRVTTGREVIELRPDVDWDKGKTLLWVLDHLPHSGSAPLVPIYLGDDITDEDAFDVVG 342
Query: 358 DKRQGLGILV---SKYAKETNASYSLQEPDEVMDFLERL 251
G+ I+V + T A ++L P V +F +RL
Sbjct: 343 P--HGVPIVVRHTDDGDRATAALFALDSPARVAEFTDRL 379
Score = 62 bits (150), Expect = 7e-009
Identities = 31/75 (41%), Positives = 45/75 (60%)
Frame = -1
Query: 990 QIVMFLDYDGTLSPIVDDPDRAFMSNKMRNTVRKLAMCFPTVIVSGRSREKVYNFVKLTE 811
Q +F D+DGTLS IV+DPD A+++ ++KLA P ++SGR V V L
Sbjct: 141 QPAVFFDFDGTLSDIVEDPDAAWLAPGALEALQKLAARCPIAVLSGRDLADVTQRVGLPG 200
Query: 810 LCYAGSHGMDIKGPE 766
+ YAGSHG ++ P+
Sbjct: 201 IWYAGSHGFELTAPD 215
>sp|O50401|OTSB_MYCTU Trehalose-phosphate phosphatase OS=Mycobacterium
tuberculosis GN=otsB PE=1 SV=1
Length = 391
Score = 92 bits (226), Expect = 1e-017
Identities = 53/159 (33%), Positives = 90/159 (56%), Gaps = 6/159 (3%)
Frame = -3
Query: 718 ATEFLPVISEVYMKLVEKTKSIQGAKVENNKFCASVHFRCVDENKWSDLAHLVRSVLKNY 539
A +PV+ + +L ++ G VE+ +F +VH+R ++ ++A VR+ + +
Sbjct: 224 AAAAIPVLKQAAAELRQQLGPFPGVVVEHKRFGVAVHYRNAARDRVGEVAAAVRTAEQRH 283
Query: 538 PKLMLTQGRKVLEIRPIIKWDKGKALEFLLESLGYENCTDVFPIYIGDDRTDEDAFKILR 359
L +T GR+V+E+RP + WDKGK L ++L+ L + + PIY+GDD TDEDAF ++
Sbjct: 284 -ALRVTTGREVIELRPDVDWDKGKTLLWVLDHLPHSGSAPLVPIYLGDDITDEDAFDVVG 342
Query: 358 DKRQGLGILV---SKYAKETNASYSLQEPDEVMDFLERL 251
G+ I+V + T A ++L P V +F +RL
Sbjct: 343 P--HGVPIVVRHTDDGDRATAALFALDSPARVAEFTDRL 379
Score = 62 bits (150), Expect = 7e-009
Identities = 31/75 (41%), Positives = 45/75 (60%)
Frame = -1
Query: 990 QIVMFLDYDGTLSPIVDDPDRAFMSNKMRNTVRKLAMCFPTVIVSGRSREKVYNFVKLTE 811
Q +F D+DGTLS IV+DPD A+++ ++KLA P ++SGR V V L
Sbjct: 141 QPAVFFDFDGTLSDIVEDPDAAWLAPGALEALQKLAARCPIAVLSGRDLADVTQRVGLPG 200
Query: 810 LCYAGSHGMDIKGPE 766
+ YAGSHG ++ P+
Sbjct: 201 IWYAGSHGFELTAPD 215
>sp|Q49734|OTSB_MYCLE Trehalose-phosphate phosphatase OS=Mycobacterium leprae
GN=otsB PE=3 SV=1
Length = 429
Score = 79 bits (194), Expect = 5e-014
Identities = 45/138 (32%), Positives = 80/138 (57%), Gaps = 5/138 (3%)
Frame = -3
Query: 706 LPVISEVYMKLVEKTKSIQGAKVENNKFCASVHFRCVDENKWSDLAHLVRSVLKNYPKLM 527
+P++ + +L ++ I G VE+ +F +VH+R V ++ +++A VR+ + L
Sbjct: 262 IPILEQAATQLRDQLGPIPGVMVEHKRFGVAVHYRNVARDRVNEVAVAVRTAGQR-NALR 320
Query: 526 LTQGRKVLEIRPIIKWDKGKALEFLLESLGYE----NCTDVFPIYIGDDRTDEDAFKILR 359
+T GR+V+E+RP I WDKGK L ++++ L + + PI +GDD TDEDAF +R
Sbjct: 321 VTTGREVIELRPDIDWDKGKTLHWVIDRLHHAGTQVGSASLMPICLGDDITDEDAFDAVR 380
Query: 358 DKRQGLGILVSKYAKETN 305
G +V ++ ++ N
Sbjct: 381 HTDVGGIPIVVRHTEDGN 398
Score = 57 bits (136), Expect = 3e-007
Identities = 30/75 (40%), Positives = 41/75 (54%)
Frame = -1
Query: 990 QIVMFLDYDGTLSPIVDDPDRAFMSNKMRNTVRKLAMCFPTVIVSGRSREKVYNFVKLTE 811
Q +F D+DGTLS IVDDPD A ++KLA P I+SGR V + +
Sbjct: 175 QPAVFFDFDGTLSDIVDDPDSARPVPGATEALQKLATHCPVAILSGRDLADVIKRIGVPG 234
Query: 810 LCYAGSHGMDIKGPE 766
+ Y+GSHG + P+
Sbjct: 235 IWYSGSHGFESTAPD 249
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 139,110,363,560
Number of Sequences: 518415
Number of Extensions: 139110363560
Number of Successful Extensions: 874217917
Number of sequences better than 0.0: 0
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