BLASTX 7.6.2
Query= UN36097 /QuerySize=684
(683 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6GPV5|RN181_XENLA E3 ubiquitin-protein ligase RNF181 OS=Xeno... 85 3e-016
sp|Q5M974|RN181_XENTR E3 ubiquitin-protein ligase RNF181 OS=Xeno... 85 3e-016
sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo... 82 2e-015
sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos ... 82 4e-015
sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus... 80 8e-015
sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Dani... 80 1e-014
sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabido... 78 5e-014
sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus ... 77 9e-014
sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN... 75 3e-013
sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevi... 72 3e-012
sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropica... 71 5e-012
sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus ... 71 7e-012
sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevi... 70 1e-011
sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo... 70 1e-011
sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN... 70 1e-011
sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=R... 69 2e-011
sp|Q8VEM1|GOLI_MOUSE Goliath homolog OS=Mus musculus GN=Rnf130 P... 67 1e-010
sp|Q6Y290|GOLI_RAT Goliath homolog OS=Rattus norvegicus GN=Rnf13... 67 1e-010
sp|Q86XS8|GOLI_HUMAN Goliath homolog OS=Homo sapiens GN=RNF130 P... 67 1e-010
sp|Q9VE61|RN181_DROME E3 ubiquitin-protein ligase CG7694 OS=Dros... 65 3e-010
>sp|Q6GPV5|RN181_XENLA E3 ubiquitin-protein ligase RNF181 OS=Xenopus laevis
GN=rnf181 PE=2 SV=1
Length = 156
Score = 85 bits (209), Expect = 3e-016
Identities = 40/97 (41%), Positives = 60/97 (61%), Gaps = 5/97 (5%)
Frame = +2
Query: 194 LNGDEFSEKQGR--SPASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEM 367
L +F+E R PASK VES+P+V + ++ A CPVCL E+ EG+ ++
Sbjct: 39 LGAVDFTEWDQRLPPPASKKVVESLPKVTVTPEQADA---ALKCPVCLLEFEEGETVRQL 95
Query: 368 PCKHRFHSKCVEEWLGRHATCPLCRYEMPVEEVEGEK 478
PC+H FHS C+ WLG+ +CPLCR+E+P + + E+
Sbjct: 96 PCEHLFHSACILPWLGKTNSCPLCRHELPTDSPDYEE 132
>sp|Q5M974|RN181_XENTR E3 ubiquitin-protein ligase RNF181 OS=Xenopus tropicalis
GN=rnf181 PE=2 SV=1
Length = 156
Score = 85 bits (209), Expect = 3e-016
Identities = 36/82 (43%), Positives = 54/82 (65%), Gaps = 3/82 (3%)
Frame = +2
Query: 233 PASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSKCVEEWL 412
PA+K VES+P+V + ++ A CPVCL E+ EG+ ++PC+H FHS C+ WL
Sbjct: 54 PAAKKVVESLPKVTVTPEQADA---ALKCPVCLLEFEEGETVRQLPCEHLFHSSCILPWL 110
Query: 413 GRHATCPLCRYEMPVEEVEGEK 478
G+ +CPLCR+E+P + E E+
Sbjct: 111 GKTNSCPLCRHELPTDSPEYEE 132
>sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo sapiens
GN=RNF181 PE=1 SV=1
Length = 153
Score = 82 bits (202), Expect = 2e-015
Identities = 37/77 (48%), Positives = 49/77 (63%), Gaps = 5/77 (6%)
Frame = +2
Query: 233 PASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSKCVEEWL 412
PA+K+ VE++PR VI R CPVCL E+ E + A EMPC H FHS C+ WL
Sbjct: 53 PAAKTVVENLPRTVI-----RGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSSCILPWL 107
Query: 413 GRHATCPLCRYEMPVEE 463
+ +CPLCRYE+P ++
Sbjct: 108 SKTNSCPLCRYELPTDD 124
>sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos taurus
GN=RNF181 PE=2 SV=1
Length = 153
Score = 82 bits (200), Expect = 4e-015
Identities = 36/77 (46%), Positives = 50/77 (64%), Gaps = 5/77 (6%)
Frame = +2
Query: 233 PASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSKCVEEWL 412
PA+K++VE++PR VI R CPVCL E+ E + A EMPC H FHS C+ WL
Sbjct: 53 PAAKTAVENLPRTVI-----RGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSNCILPWL 107
Query: 413 GRHATCPLCRYEMPVEE 463
+ +CPLCR+E+P ++
Sbjct: 108 SKTNSCPLCRHELPTDD 124
>sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus norvegicus
GN=Rnf181 PE=1 SV=1
Length = 165
Score = 80 bits (197), Expect = 8e-015
Identities = 36/77 (46%), Positives = 49/77 (63%), Gaps = 5/77 (6%)
Frame = +2
Query: 233 PASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSKCVEEWL 412
PA+K+ VES+PR VI R+ CPVCL E+ E + EMPC H FHS C+ WL
Sbjct: 65 PAAKAVVESLPRTVI-----RSSKAELKCPVCLLEFEEEETVIEMPCHHLFHSNCILPWL 119
Query: 413 GRHATCPLCRYEMPVEE 463
+ +CPLCR+E+P ++
Sbjct: 120 SKTNSCPLCRHELPTDD 136
>sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Danio rerio
GN=rnf181 PE=2 SV=2
Length = 156
Score = 80 bits (196), Expect = 1e-014
Identities = 35/82 (42%), Positives = 52/82 (63%), Gaps = 3/82 (3%)
Frame = +2
Query: 233 PASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSKCVEEWL 412
PA+K+ V+S+P V+I ++ G CPVCL E+ E + EMPCKH FH+ C+ WL
Sbjct: 54 PAAKAVVQSLPVVIISPEQ---ADKGVKCPVCLLEFEEQESVREMPCKHLFHTGCILPWL 110
Query: 413 GRHATCPLCRYEMPVEEVEGEK 478
+ +CPLCR E+P + + E+
Sbjct: 111 NKTNSCPLCRLELPTDNADYEE 132
>sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabidopsis thaliana
GN=AIP2 PE=1 SV=1
Length = 310
Score = 78 bits (190), Expect = 5e-014
Identities = 31/81 (38%), Positives = 48/81 (59%)
Frame = +2
Query: 233 PASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSKCVEEWL 412
PASK VE +P ++ ++ + G C +C E GD E+PCKH FH C++ WL
Sbjct: 202 PASKEVVEKLPVIIFTEELLKKFGAEAECCICKENLVIGDKMQELPCKHTFHPPCLKPWL 261
Query: 413 GRHATCPLCRYEMPVEEVEGE 475
H +CP+CR+E+P ++ + E
Sbjct: 262 DEHNSCPICRHELPTDDQKYE 282
>sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus musculus
GN=Rnf181 PE=2 SV=1
Length = 165
Score = 77 bits (188), Expect = 9e-014
Identities = 34/77 (44%), Positives = 47/77 (61%), Gaps = 5/77 (6%)
Frame = +2
Query: 233 PASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSKCVEEWL 412
PA+K+ VES+PR VI + CPVCL E+ + EMPC H FHS C+ WL
Sbjct: 65 PAAKAVVESLPRTVISSAKADL-----KCPVCLLEFEAEETVIEMPCHHLFHSNCILPWL 119
Query: 413 GRHATCPLCRYEMPVEE 463
+ +CPLCR+E+P ++
Sbjct: 120 SKTNSCPLCRHELPTDD 136
>sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN=Rnf126 PE=1
SV=1
Length = 313
Score = 75 bits (183), Expect = 3e-013
Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 3/117 (2%)
Frame = +2
Query: 215 EKQGRSPASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSK 394
E G PA K ++++P V + E G G CPVC E+++ G+ ++PC H FH
Sbjct: 200 ENTGPPPADKEKIQALPTVPV---TEEHVGSGLECPVCKEDYALGESVRQLPCNHLFHDS 256
Query: 395 CVEEWLGRHATCPLCRYEMPVEEVEGEKKVGVWIGFAVGSGERRSEGDGGRRSDGDS 565
C+ WL +H +CP+CR + + +GF+ S S + +S
Sbjct: 257 CIVPWLEQHDSCPVCRKSLTGQNTATNPPGLTGVGFSSSSSSSSSSSPSNENATSNS 313
>sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevis GN=rnf126-a
PE=2 SV=1
Length = 312
Score = 72 bits (175), Expect = 3e-012
Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 3/76 (3%)
Frame = +2
Query: 215 EKQGRSPASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSK 394
E G PA ++++P + I E G G CPVC E+++ G+ ++PC H FH+
Sbjct: 197 ENTGPPPADNEKIQALPTIQI---TEEHVGSGLECPVCKEDYTVGECVRQLPCNHLFHND 253
Query: 395 CVEEWLGRHATCPLCR 442
C+ WL +H TCP+CR
Sbjct: 254 CIIPWLEQHDTCPVCR 269
>sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropicalis GN=rnf126
PE=2 SV=1
Length = 311
Score = 71 bits (173), Expect = 5e-012
Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 3/76 (3%)
Frame = +2
Query: 215 EKQGRSPASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSK 394
E G PA ++++P + I E G G CPVC E+++ G+ ++PC H FH+
Sbjct: 196 ENTGPPPADTEKIQALPTIQI---TEEHVGSGLECPVCKEDYTVGESVRQLPCNHLFHND 252
Query: 395 CVEEWLGRHATCPLCR 442
C+ WL +H TCP+CR
Sbjct: 253 CIIPWLEQHDTCPVCR 268
>sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus musculus
GN=Rnf115 PE=1 SV=1
Length = 305
Score = 71 bits (172), Expect = 7e-012
Identities = 30/83 (36%), Positives = 46/83 (55%), Gaps = 3/83 (3%)
Frame = +2
Query: 215 EKQGRSPASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSK 394
E G PA K + S+P V + +++ G CPVC E+++ + ++PC H FHS
Sbjct: 198 ENTGPPPADKEKITSLPTVTVTQEQVNT---GLECPVCKEDYTVEEKVRQLPCNHFFHSS 254
Query: 395 CVEEWLGRHATCPLCRYEMPVEE 463
C+ WL H TCP+CR + E+
Sbjct: 255 CIVPWLELHDTCPVCRKSLNGED 277
>sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevis GN=rnf126-b
PE=2 SV=1
Length = 312
Score = 70 bits (170), Expect = 1e-011
Identities = 29/76 (38%), Positives = 44/76 (57%), Gaps = 3/76 (3%)
Frame = +2
Query: 215 EKQGRSPASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSK 394
E G PA ++++P + I E G G CPVC E+++ G+ ++PC H FH+
Sbjct: 197 ENTGPPPADTDKIQALPTIQI---TEEHVGFGLECPVCKEDYTVGESVRQLPCNHLFHND 253
Query: 395 CVEEWLGRHATCPLCR 442
C+ WL +H TCP+CR
Sbjct: 254 CIIPWLEQHDTCPVCR 269
>sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo sapiens
GN=RNF115 PE=1 SV=2
Length = 304
Score = 70 bits (169), Expect = 1e-011
Identities = 30/83 (36%), Positives = 46/83 (55%), Gaps = 3/83 (3%)
Frame = +2
Query: 215 EKQGRSPASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSK 394
E G PA K + S+P V + +++ G CPVC E+++ + ++PC H FHS
Sbjct: 197 ENTGPPPADKEKITSLPTVTVTQEQVDM---GLECPVCKEDYTVEEEVRQLPCNHFFHSS 253
Query: 395 CVEEWLGRHATCPLCRYEMPVEE 463
C+ WL H TCP+CR + E+
Sbjct: 254 CIVPWLELHDTCPVCRKSLNGED 276
>sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN=RNF126 PE=1
SV=1
Length = 326
Score = 70 bits (169), Expect = 1e-011
Identities = 28/76 (36%), Positives = 44/76 (57%), Gaps = 3/76 (3%)
Frame = +2
Query: 215 EKQGRSPASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSK 394
E G PA K ++++P V + E G G CPVC ++++ G+ ++PC H FH
Sbjct: 198 ENTGPPPADKEKIQALPTVPV---TEEHVGSGLECPVCKDDYALGERVRQLPCNHLFHDG 254
Query: 395 CVEEWLGRHATCPLCR 442
C+ WL +H +CP+CR
Sbjct: 255 CIVPWLEQHDSCPVCR 270
>sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=RNF126 PE=2
SV=1
Length = 313
Score = 69 bits (168), Expect = 2e-011
Identities = 28/76 (36%), Positives = 43/76 (56%), Gaps = 3/76 (3%)
Frame = +2
Query: 215 EKQGRSPASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSK 394
E G PA K ++++P V + E G G CPVC +++ G+ ++PC H FH
Sbjct: 201 ENTGPPPADKEKIQALPTVPV---TEEHVGSGLECPVCKDDYGLGEHVRQLPCNHLFHDG 257
Query: 395 CVEEWLGRHATCPLCR 442
C+ WL +H +CP+CR
Sbjct: 258 CIVPWLEQHDSCPVCR 273
>sp|Q8VEM1|GOLI_MOUSE Goliath homolog OS=Mus musculus GN=Rnf130 PE=2 SV=1
Length = 419
Score = 67 bits (162), Expect = 1e-010
Identities = 24/69 (34%), Positives = 38/69 (55%)
Frame = +2
Query: 236 ASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSKCVEEWLG 415
A+K ++ + + K ++ C VC+E + + DV +PCKH FH CV+ WL
Sbjct: 237 AAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVVRVLPCKHVFHKSCVDPWLS 296
Query: 416 RHATCPLCR 442
H TCP+C+
Sbjct: 297 EHCTCPMCK 305
>sp|Q6Y290|GOLI_RAT Goliath homolog OS=Rattus norvegicus GN=Rnf130 PE=1 SV=1
Length = 419
Score = 67 bits (162), Expect = 1e-010
Identities = 24/69 (34%), Positives = 38/69 (55%)
Frame = +2
Query: 236 ASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSKCVEEWLG 415
A+K ++ + + K ++ C VC+E + + DV +PCKH FH CV+ WL
Sbjct: 237 AAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVVRVLPCKHVFHKSCVDPWLS 296
Query: 416 RHATCPLCR 442
H TCP+C+
Sbjct: 297 EHCTCPMCK 305
>sp|Q86XS8|GOLI_HUMAN Goliath homolog OS=Homo sapiens GN=RNF130 PE=1 SV=1
Length = 419
Score = 67 bits (161), Expect = 1e-010
Identities = 24/69 (34%), Positives = 38/69 (55%)
Frame = +2
Query: 236 ASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSKCVEEWLG 415
A+K ++ + + K ++ C VC+E + + DV +PCKH FH CV+ WL
Sbjct: 237 AAKKAISKLTTRTVKKGDKETDPDFDHCAVCIESYKQNDVVRILPCKHVFHKSCVDPWLS 296
Query: 416 RHATCPLCR 442
H TCP+C+
Sbjct: 297 EHCTCPMCK 305
>sp|Q9VE61|RN181_DROME E3 ubiquitin-protein ligase CG7694 OS=Drosophila
melanogaster GN=CG7694 PE=2 SV=1
Length = 147
Score = 65 bits (158), Expect = 3e-010
Identities = 31/76 (40%), Positives = 43/76 (56%), Gaps = 3/76 (3%)
Frame = +2
Query: 236 ASKSSVESMPRVVIGKDEERAGGGGGSCPVCLEEWSEGDVASEMPCKHRFHSKCVEEWLG 415
ASK ++ +P I K +E GG C VC E EG +PCKH FH +C+ WL
Sbjct: 46 ASKRAILELPVHEIVKSDE---GGDLECSVCKEPAEEGQKYRILPCKHEFHEECILLWLK 102
Query: 416 RHATCPLCRYEMPVEE 463
+ +CPLCRYE+ ++
Sbjct: 103 KTNSCPLCRYELETDD 118
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 142,442,557,381
Number of Sequences: 518415
Number of Extensions: 142442557381
Number of Successful Extensions: 892588021
Number of sequences better than 0.0: 0
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