BLASTX 7.6.2
Query= UN37050 /QuerySize=1297
(1296 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O60318|MCM3A_HUMAN 80 kDa MCM3-associated protein OS=Homo sap... 112 5e-024
sp|Q9WUU9|MCM3A_MOUSE 80 kDa MCM3-associated protein OS=Mus musc... 109 4e-023
sp|O74889|SAC31_SCHPO SAC3 family protein 1 OS=Schizosaccharomyc... 102 7e-021
sp|Q9USI4|SAC32_SCHPO SAC3 family protein 2 OS=Schizosaccharomyc... 94 2e-018
sp|Q9U3V9|XMAS2_DROME Protein xmas-2 OS=Drosophila melanogaster ... 93 3e-018
sp|P46674|SAC3_YEAST Nuclear mRNA export protein SAC3 OS=Sacchar... 89 6e-017
>sp|O60318|MCM3A_HUMAN 80 kDa MCM3-associated protein OS=Homo sapiens GN=MCM3AP
PE=1 SV=2
Length = 1980
Score = 112 bits (280), Expect = 5e-024
Identities = 93/318 (29%), Positives = 158/318 (49%), Gaps = 28/318 (8%)
Frame = +3
Query: 213 VGTCSSMCPERERVTRERLRDLLVFERLYGNPTKSSTH-LAVKKFCRTLSAADVQ---AS 380
VGTC MCPE+ER RE L VFE + G T H AVK++ R S+AD +
Sbjct: 634 VGTCLDMCPEKERYMRETRSQLSVFEVVPG--TDQVDHAAAVKEYSR--SSADQEEPLPH 689
Query: 381 DIRPLPVLEETLSYLLS-LLDSREHPFEVVHDFIFDRTRSIRQDLSIQNLANERVIHLYE 557
++RPLPVL T+ YL++ ++D +E +DF+++RTR IR+D++ Q+L + + L E
Sbjct: 690 ELRPLPVLSRTMDYLVTQIMDQKEGSLRDWYDFVWNRTRGIRKDITQQHLCDPLTVSLIE 749
Query: 558 EIVKFHVISGQRLQGSSGANVSSMHHLNMEQLAKTLTTLYNIYDVNRKPDYIYENEAEFR 737
+ +FH+ + ++ + +N E + K L +L +Y R +EAEF+
Sbjct: 750 KCTRFHIHCAHFMCEEPMSSFDA--KINNENMTKCLQSLKEMYQDLRNKGVFCASEAEFQ 807
Query: 738 SLYVLLHLNTSSGVMGEPLSLWFRKLTSNLIKSEEMCFVRNLLRSYRNGNYQSFLRTTAT 917
VLL LN ++ E ++ + S E+ F + + N+ F + +
Sbjct: 808 GYNVLLSLN-KGDILRE-----VQQFHPAVRNSSEVKFAVQAFAALNSNNFVRFFKLVQS 861
Query: 918 EATYLQYCISEPHIREMRSFAVECINNVCYKLQP-----YPLLQISQHLMMKEMDVESLC 1082
A+YL C+ + ++R A+ + N Y + +PL + + L+ ++ + +
Sbjct: 862 -ASYLNACLLHCYFSQIRKDALRAL-NFAYTVSTQRSTIFPLDGVVRMLLFRDCEEATDF 919
Query: 1083 QEC-GLEIRTDSDGCIVL 1133
C GL T SDGC+ L
Sbjct: 920 LTCHGL---TVSDGCVEL 934
>sp|Q9WUU9|MCM3A_MOUSE 80 kDa MCM3-associated protein OS=Mus musculus GN=Mcm3ap
PE=2 SV=1
Length = 1971
Score = 109 bits (272), Expect = 4e-023
Identities = 90/317 (28%), Positives = 155/317 (48%), Gaps = 26/317 (8%)
Frame = +3
Query: 213 VGTCSSMCPERERVTRERLRDLLVFERLYGNPTKSSTH-LAVKKFCRTLSAADVQ---AS 380
VGTC MCPE+ER RE L VFE + G T H AVK++ R S+AD +
Sbjct: 627 VGTCPDMCPEKERYLRETRSQLSVFEVVPG--TDQVDHAAAVKEYSR--SSADQEEPLPH 682
Query: 381 DIRPLPVLEETLSYLLS-LLDSREHPFEVVHDFIFDRTRSIRQDLSIQNLANERVIHLYE 557
++RP VL T+ YL++ ++D +E +DF+++RTR IR+D++ Q+L + + L E
Sbjct: 683 ELRPSAVLSRTMDYLVTQIMDQKEGSLRDWYDFVWNRTRGIRKDITQQHLCDPLTVSLIE 742
Query: 558 EIVKFHVISGQRLQGSSGANVSSMHHLNMEQLAKTLTTLYNIYDVNRKPDYIYENEAEFR 737
+ +FH+ + ++ + +N E + K L +L +Y R +EAEF+
Sbjct: 743 KCTRFHIHCAHFMCEEPMSSFDA--KINNENMTKCLQSLKEMYQDLRNKGVFCASEAEFQ 800
Query: 738 SLYVLLHLNTSSGVMGEPLSLWFRKLTSNLIKSEEMCFVRNLLRSYRNGNYQSFLRTTAT 917
VLL+LN ++ E ++ ++ S E+ F + + N+ F + +
Sbjct: 801 GYNVLLNLN-KGDILRE-----VQQFHPDVRNSPEVNFAVQAFAALNSNNFVRFFKLVQS 854
Query: 918 EATYLQYCISEPHIREMRSFAVECINNVCYKLQP-----YPLLQISQHLMMKEMDVESLC 1082
A+YL C+ + ++R A+ + NV Y + +PL + + L+ + D E
Sbjct: 855 -ASYLNACLLHCYFNQIRKDALRAL-NVAYTVSTQRSTVFPLDGVVRMLLFR--DSEEAT 910
Query: 1083 QECGLEIRTDSDGCIVL 1133
T +DGC+ L
Sbjct: 911 NFLNYHGLTVADGCVEL 927
>sp|O74889|SAC31_SCHPO SAC3 family protein 1 OS=Schizosaccharomyces pombe
GN=SPCC576.05 PE=1 SV=1
Length = 1024
Score = 102 bits (253), Expect = 7e-021
Identities = 74/193 (38%), Positives = 101/193 (52%), Gaps = 13/193 (6%)
Frame = +3
Query: 198 EVSFIVGTCSSMCPERERVTRERLRDLLVFERLYGNPT--KSSTHLAVKKFCRTLSAADV 371
E VGTC MCPE ER RE +L ER NP + +LAVK F R +A +
Sbjct: 100 EAVTFVGTCPDMCPEYEREQREYQNNL---ERWEINPETGRVDKNLAVKAFHRP-AAGNE 155
Query: 372 QA--SDIRPLPVLEETLSYLLSLLDSREHPFEVVHDFIFDRTRSIRQDLSIQNLANERVI 545
QA SD+RP PVL+++L YL+ + P E H F+ DRTRSIRQD ++QN + +
Sbjct: 156 QALPSDVRPPPVLKKSLDYLVDKIVCGPDPLENTHFFVRDRTRSIRQDFTLQNCRDLDAV 215
Query: 546 HLYEEIVKFHVISGQRLQGSSGANVSSMHHLNMEQLAK-TLTTLYNIYDVNRKPDYIYEN 722
+E I ++H++ +L + +EQL K L +L YD RK N
Sbjct: 216 ACHERIARYHILCIHQLCEKKQFSAQQ----EVEQLRKGILQSLCEFYDDLRKVKIRCPN 271
Query: 723 EAEFRSLYVLLHL 761
E EFRS ++ HL
Sbjct: 272 EPEFRSYAIITHL 284
>sp|Q9USI4|SAC32_SCHPO SAC3 family protein 2 OS=Schizosaccharomyces pombe
GN=SPCC70.06 PE=2 SV=1
Length = 458
Score = 94 bits (232), Expect = 2e-018
Identities = 69/215 (32%), Positives = 108/215 (50%), Gaps = 14/215 (6%)
Frame = +3
Query: 147 RKRNNKGGEAAAAAAAAEVSFIVGTCSSMCPERERVTRERLRDLLVFERLYGNPTKSSTH 326
RK + +A + + S +VGTC MCPE E R+ + +E +P H
Sbjct: 49 RKDEQESFQAKQSTNWEKSSVLVGTCRQMCPEFELEERKLQHAIHPYEL---DPVSKQAH 105
Query: 327 --LAVKKFCRTLSA-ADVQASDIRPLPVLEETLSYLLSLLDSREHPFEVVHDFIFDRTRS 497
LAVK + R + + SD+RP +L+ T+ YL ++ R + H F+ DRTR+
Sbjct: 106 PSLAVKAYHRPAAGKGPILPSDVRPPSILKNTIDYLFKVILDR-YSLREAHAFVRDRTRA 164
Query: 498 IRQDLSIQNLANERVIHLYEEIVKFHVISGQRLQGSSGANVSSMHHLNMEQLAKTLTTLY 677
+RQD S+Q+ ++ ++ +E I +FH+IS L + N S + EQL+K++ LY
Sbjct: 165 VRQDFSVQSSFSQDSVYCHELIARFHIISLHEL--AHTPNFSRQQEI--EQLSKSMEILY 220
Query: 678 ---NIYDVNRKPDYIYENEAEFRSLYVLLHLNTSS 773
+YD +EAEFR+ VLL L S
Sbjct: 221 TLGQLYDYMHLRKEHCTHEAEFRAYMVLLSLGDPS 255
>sp|Q9U3V9|XMAS2_DROME Protein xmas-2 OS=Drosophila melanogaster GN=xmas-2 PE=1
SV=3
Length = 1370
Score = 93 bits (230), Expect = 3e-018
Identities = 95/349 (27%), Positives = 159/349 (45%), Gaps = 39/349 (11%)
Frame = +3
Query: 216 GTCSSMCPERERVTRERLRDLLVFERLYGNPTKSSTHLAVKKFCRTLSAADVQA---SDI 386
G C+ MCPE+ERV RE R + +E G+ A+K++ R S+AD + ++
Sbjct: 200 GHCADMCPEKERVLREFQRQVAYYELQPGSDELICHERALKQYSR--SSADQETPLPHEL 257
Query: 387 RPLPVLEETLSYLLSLL-------DSREHPFEVVHDFIFDRTRSIRQDLSIQNLANERVI 545
R L T+SYL+ + D + H + H F++DRTRSIR++++ Q L + +
Sbjct: 258 RNETALHMTMSYLMHEIMDISERQDPQSHMGDWFH-FVWDRTRSIRKEITQQELCSLGAV 316
Query: 546 HLYEEIVKFHVISGQRLQGSSGANVSSMHHLNMEQLAKTLTTLYNIYDVNRKPDYIYENE 725
L E+ +FH+ RL + + S +N E L K L TL +Y R E
Sbjct: 317 KLVEQCARFHIHCAARLVDADPSVFDS--KINAENLTKCLQTLKYMYHDLRIKGVPCPKE 374
Query: 726 AEFRSLYVLLHLNTSSGVMGEPLSLW-FRKLTSNLIKSEEMCFVRNLLRSYRNGNYQSFL 902
AEFR VLL+L ++ LW +L + L E+ + ++ N+ F
Sbjct: 375 AEFRGYIVLLNLADAN-------FLWDIGQLPAELQSCPEVRQAIQFYLALQDTNFVRFF 427
Query: 903 RTTATEAT-YLQYCISEPHIREMRSFAVECINNVCY-----KLQPYPLLQISQHL-MMKE 1061
+ A + T YL CI + +R + + ++ PL I++ L E
Sbjct: 428 QLLADKDTSYLSACILVNYFTRLRVLGLHRLIQAYRSPRKDEVSSLPLSYIAELLSFASE 487
Query: 1062 MDVESLCQECGLEIRTDSDGCIVLP---TKQTNFRSPKEGFKNYDLIGI 1199
+ Q GL+I + G +VL T +T ++ P++ Y+L+ +
Sbjct: 488 QEAADFVQHYGLQI--NEAGRVVLSRMHTVETEYKLPRQ----YELVEV 530
>sp|P46674|SAC3_YEAST Nuclear mRNA export protein SAC3 OS=Saccharomyces
cerevisiae GN=SAC3 PE=1 SV=2
Length = 1301
Score = 89 bits (219), Expect = 6e-017
Identities = 66/181 (36%), Positives = 90/181 (49%), Gaps = 8/181 (4%)
Frame = +3
Query: 216 GTCSSMCPERERVTRERLRDLLVFERLYGNPTKSSTHLAVKKFCR-TLSAADVQASDIRP 392
GTC MCP ER R + +E+ N K+S A+K F R +AA SD+RP
Sbjct: 198 GTCLDMCPTFERSRRNVEYTVYSYEKNQPNDKKASRTKALKVFARPAAAAAPPLPSDVRP 257
Query: 393 LPVLEETLSYLLSLLDSREHPFEVVHDFIFDRTRSIRQDLSIQNLANERVIHLYEEIVKF 572
+L +TL Y ++D+ F++DR RSIRQD + QN + + E IV+
Sbjct: 258 PHILVKTLDY---IVDNLLTTLPESEGFLWDRMRSIRQDFTYQNYSGPEAVDCNERIVRI 314
Query: 573 HVISGQRLQGSSGANVSSMHHLNMEQLAKTLTTLYNIYDVNRKPDYIYENEAEFRSLYVL 752
H++ L +NV +EQL K+L TL IYD R NEAEFR+ Y L
Sbjct: 315 HLLI---LHIMVKSNVEFSLQQELEQLHKSLITLSEIYDDVRSSGGTCPNEAEFRA-YAL 370
Query: 753 L 755
L
Sbjct: 371 L 371
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 145,264,384,081
Number of Sequences: 518415
Number of Extensions: 145264384081
Number of Successful Extensions: 900894833
Number of sequences better than 0.0: 0
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