BLASTX 7.6.2
Query= UN37868 /QuerySize=1524
(1523 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6INH1|RN157_XENLA RING finger protein 157 OS=Xenopus laevis ... 135 9e-031
sp|Q96PX1|RN157_HUMAN RING finger protein 157 OS=Homo sapiens GN... 133 4e-030
sp|Q3TEL6|RN157_MOUSE RING finger protein 157 OS=Mus musculus GN... 131 2e-029
sp|Q7ZUL9|MGRN1_DANRE Probable E3 ubiquitin-protein ligase MGRN1... 128 1e-028
sp|Q5XIQ4|MGRN1_RAT Probable E3 ubiquitin-protein ligase MGRN1 O... 126 4e-028
sp|O60291|MGRN1_HUMAN Probable E3 ubiquitin-protein ligase MGRN1... 124 2e-027
sp|Q9D074|MGRN1_MOUSE Probable E3 ubiquitin-protein ligase MGRN1... 124 3e-027
sp|Q1A1A1|FOXG1_CERSI Forkhead box protein G1 OS=Ceratotherium s... 55 9e-007
sp|Q1A1A2|FOXG1_EQUBU Forkhead box protein G1 OS=Equus burchelli... 55 9e-007
sp|Q1A1A5|FOXG1_CERPY Forkhead box protein G1 OS=Cercopithecus p... 55 2e-006
sp|P55316|FOXG1_HUMAN Forkhead box protein G1 OS=Homo sapiens GN... 55 2e-006
sp|O10296|IAP1_NPVOP Apoptosis inhibitor 1 OS=Orgyia pseudotsuga... 54 2e-006
sp|Q7M3S9|RNGB_DICDI RING finger protein B OS=Dictyostelium disc... 53 5e-006
sp|Q1A1A6|FOXG1_CEBCA Forkhead box protein G1 OS=Cebus capucinus... 53 6e-006
>sp|Q6INH1|RN157_XENLA RING finger protein 157 OS=Xenopus laevis GN=rnf157 PE=2
SV=1
Length = 674
Score = 135 bits (339), Expect = 9e-031
Identities = 105/314 (33%), Positives = 157/314 (50%), Gaps = 26/314 (8%)
Frame = -3
Query: 1221 HPPPQINY-GSYGYNYNPNPQQQQPPPYFYNGWNNTM----MRPVFYGPAPVVVDQQPPQ 1057
+PP +Y GS+ + P Y + G N+ + RPV + P Q+P +
Sbjct: 25 YPPKSGSYFGSHFIMGGEKFESSHPEGYLF-GENSDLNFLGSRPVTF-PYTAPSPQEPVK 82
Query: 1056 ALVEHQSAKKVRND-VNVHKDTVRLES---DDLNPGYHL-VSFLFDAVFDGSFTIIFFAK 892
L +S +R D + + + T L++ + P H V F FD + T+ + A
Sbjct: 83 TL---RSLINIRKDTLRLVRCTEELKTTGVEGSRPKVHYNVEFTFDTDARVAITMYYQAT 139
Query: 891 EEENCTIVPHYPEA--FRPTKVPFQKGTAQKFIQPSGTGTDLGFFSLDDLSSPSPEEVYP 718
EE I + P++ + V F++G +Q+F PS T D + ++L+ EVYP
Sbjct: 140 EEFQGGIPSYLPKSSNLQSDTVHFKRGVSQQFCFPSHT-VDPSEWREEELTFDLDREVYP 198
Query: 717 LVISAETVISPSSGSEEPLVHKQVTHACLEKADGDGSFKVKVVKQILWIEGARYELRELY 538
+V+ A EE L H V A EK DGSF VK +KQ ++G Y L+E+Y
Sbjct: 199 MVVHAVV-----EEGEEHLGHSHVLMATFEK-HADGSFCVKPLKQKQVVDGVSYLLQEIY 252
Query: 537 GIDNSTAQDD--VASGLEDSGDKECVICLTEPKDTAVMPCRHLCLCSDCAKELRFQSNKC 364
GI+N D VA ECV+CL++ +DT ++PCRHLCLC+ CA LR+Q++ C
Sbjct: 253 GIENKYNSQDSKVAEDELSDNSAECVVCLSDVRDTLILPCRHLCLCNACADTLRYQASNC 312
Query: 363 PICRQPIDELLMIK 322
PICR P LL I+
Sbjct: 313 PICRLPFRALLQIR 326
>sp|Q96PX1|RN157_HUMAN RING finger protein 157 OS=Homo sapiens GN=RNF157 PE=2
SV=3
Length = 679
Score = 133 bits (334), Expect = 4e-030
Identities = 95/275 (34%), Positives = 137/275 (49%), Gaps = 25/275 (9%)
Frame = -3
Query: 1101 FYGPAPVVVD--QQPPQALVEH-QSAKKVRNDVNVHKDTVRLESDDLNPG--------YH 955
F G PVV PPQ V+ +S +R D V+ + +PG ++
Sbjct: 62 FLGNRPVVFPYAAPPPQEPVKTLRSLVNIRKDT---LRLVKCAEEVKSPGEEASKAKVHY 118
Query: 954 LVSFLFDAVFDGSFTIIFFAKEEENCTIVPHYPE--AFRPTKVPFQKGTAQKFIQPSGTG 781
V F FD + TI + A EE I + P+ + + V +++G Q+F PS T
Sbjct: 119 NVEFTFDTDARVAITIYYQATEEFQNGIASYIPKDNSLQSETVQYKRGVCQQFCLPSHT- 177
Query: 780 TDLGFFSLDDLSSPSPEEVYPLVISAETVISPSSGSEEPLVHKQVTHACLEKADGDGSFK 601
D ++ ++L EVYPLV+ A +E H V EK DG+F
Sbjct: 178 VDPSEWAEEELGFDLDREVYPLVVHAVV-----DEGDEYFGHCHVLLGTFEK-HTDGTFC 231
Query: 600 VKVVKQILWIEGARYELRELYGIDN--STAQDDVASGLEDSGDKECVICLTEPKDTAVMP 427
VK +KQ ++G Y L+E+YGI+N +T VA ECV+CL++ +DT ++P
Sbjct: 232 VKPLKQKQVVDGVSYLLQEIYGIENKYNTQDSKVAEDEVSDNSAECVVCLSDVRDTLILP 291
Query: 426 CRHLCLCSDCAKELRFQSNKCPICRQPIDELLMIK 322
CRHLCLC+ CA LR+Q+N CPICR P LL I+
Sbjct: 292 CRHLCLCNTCADTLRYQANNCPICRLPFRALLQIR 326
>sp|Q3TEL6|RN157_MOUSE RING finger protein 157 OS=Mus musculus GN=Rnf157 PE=2
SV=2
Length = 685
Score = 131 bits (327), Expect = 2e-029
Identities = 94/272 (34%), Positives = 137/272 (50%), Gaps = 19/272 (6%)
Frame = -3
Query: 1101 FYGPAPVVVD--QQPPQALVEH-QSAKKVRND-VNVHKDTVRLESDDLNPG----YHLVS 946
F G PV PPQ V+ +S +R D + + K ++S G ++ V
Sbjct: 62 FLGNRPVAFPYAAPPPQEPVKTLRSLINIRKDTLRLVKCAEEVKSHGEEAGKAKVHYNVE 121
Query: 945 FLFDAVFDGSFTIIFFAKEEENCTIVPHYPE--AFRPTKVPFQKGTAQKFIQPSGTGTDL 772
F FD + TI + A EE I + P+ + + V +++G Q+F PS T D
Sbjct: 122 FTFDTDARVAITIYYQATEEFQNGIASYIPKDNSLQSETVHYKRGVFQQFCLPSHT-VDP 180
Query: 771 GFFSLDDLSSPSPEEVYPLVISAETVISPSSGSEEPLVHKQVTHACLEKADGDGSFKVKV 592
++ ++L EVYPLV+ A +E H V EK DG+F VK
Sbjct: 181 SEWAEEELGFDLDREVYPLVVHAVV-----DEGDEYFGHCHVLLGTFEK-HPDGTFCVKP 234
Query: 591 VKQILWIEGARYELRELYGIDNSTAQDDVASGLEDSGDK--ECVICLTEPKDTAVMPCRH 418
+KQ ++G Y L+E+YGI+N D +D D ECV+CL++ +DT ++PCRH
Sbjct: 235 LKQKQVVDGVSYLLQEIYGIENKYNTQDSKVAEDDVSDNSAECVVCLSDVRDTLILPCRH 294
Query: 417 LCLCSDCAKELRFQSNKCPICRQPIDELLMIK 322
LCLC+ CA LR+Q+N CPICR P LL I+
Sbjct: 295 LCLCNTCADTLRYQANNCPICRLPFRALLQIR 326
>sp|Q7ZUL9|MGRN1_DANRE Probable E3 ubiquitin-protein ligase MGRN1 OS=Danio rerio
GN=mgrn1 PE=2 SV=1
Length = 529
Score = 128 bits (320), Expect = 1e-028
Identities = 99/314 (31%), Positives = 148/314 (47%), Gaps = 27/314 (8%)
Frame = -3
Query: 1221 HPPPQINYGSYGYNYNPNPQQQQPPPYFYNGWNNTMMRPVFYGPAPVVVDQQPPQALVEH 1042
+PP NY + + P + G N M F G PV P A H
Sbjct: 25 YPPKSGNYFTSHFFMGGEKFDTPHPEGYLFGEN---MDLNFLGNRPVQFPYVTPAA---H 78
Query: 1041 QSAKKVRNDVNVHKDTVRL----ESDDLNPG-------YHLVSFLFDAVFDGSFTIIFFA 895
+ K +R+ VN+ KD++RL + D P + V F FD + T+ A
Sbjct: 79 EPVKTLRSLVNIRKDSLRLVRYKDDSDSTPEDTGDPRVLYSVEFCFDTDARVAITLYCQA 138
Query: 894 KEE--ENCTIVPHYPEAFRPTKVPFQKGTAQKFIQPSGTGTDLGFFSLDDLSSPSPEEVY 721
EE I + V +++G Q+F PS D + ++L+ + V+
Sbjct: 139 FEEFANGMAIYSAKSPSMVSETVHYKRGINQQFSLPS-FKIDFTKWKPEELNFDLDKGVF 197
Query: 720 PLVISAETVISPSSGSEEPLVHKQVTHACLEKADGDGSFKVKVVKQILWIEGARYELREL 541
PLV+ A ++ H V A E+ DGSF VK +KQ ++ Y L+E+
Sbjct: 198 PLVVQAIV-----DDGDDVTGHAHVLLAAFER-HVDGSFSVKPLKQKQIVDRVSYLLQEI 251
Query: 540 YGIDNSTAQDDVASGLEDS-GDKECVICLTEPKDTAVMPCRHLCLCSDCAKELRFQSNKC 364
YGI+N Q+ ++ E+S ECV+CL++ +DT ++PCRHLCLC+ CA LR+Q+N C
Sbjct: 252 YGIENRNNQETKSTEDENSDNSSECVVCLSDLRDTLILPCRHLCLCNACADTLRYQANNC 311
Query: 363 PICRQPIDELLMIK 322
PICR P LL I+
Sbjct: 312 PICRLPFRALLQIR 325
>sp|Q5XIQ4|MGRN1_RAT Probable E3 ubiquitin-protein ligase MGRN1 OS=Rattus
norvegicus GN=Mgrn1 PE=2 SV=1
Length = 533
Score = 126 bits (316), Expect = 4e-028
Identities = 93/271 (34%), Positives = 132/271 (48%), Gaps = 16/271 (5%)
Frame = -3
Query: 1101 FYGPAPV---VVDQQPPQALVEHQSAKKVRND----VNVHKDTVRLESDDLNPG-YHLVS 946
F G PV V P + + +S +R D V DT D P + +
Sbjct: 63 FLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVRYKDDTDSPTEDGEKPRVLYSLE 122
Query: 945 FLFDAVFDGSFTIIFFAKEE--ENCTIVPHYPEAFRPTKVPFQKGTAQKFIQPSGTGTDL 772
F FDA + TI A EE T+ + + V +++G +Q+F PS D
Sbjct: 123 FTFDADARVAITIYCQAVEEFVNGMTVYSCKNPSLQSETVHYKRGVSQQFSLPS-FKIDF 181
Query: 771 GFFSLDDLSSPSPEEVYPLVISAETVISPSSGSEEPLVHKQVTHACLEKADGDGSFKVKV 592
+ D+L+ V+P+VI A + E H V A EK DGSF VK
Sbjct: 182 SEWKDDELNFDLDRGVFPVVIQA---VVDEGDVVEVTGHAHVLLAAFEK-HVDGSFSVKP 237
Query: 591 VKQILWIEGARYELRELYGIDNSTAQDDVASGLEDS-GDKECVICLTEPKDTAVMPCRHL 415
+KQ ++ Y L+E+YGI+N Q+ S E+S ECV+CL++ +DT ++PCRHL
Sbjct: 238 LKQKQIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSSECVVCLSDLRDTLILPCRHL 297
Query: 414 CLCSDCAKELRFQSNKCPICRQPIDELLMIK 322
CLC+ CA LR+Q+N CPICR P LL I+
Sbjct: 298 CLCTSCADTLRYQANNCPICRLPFRALLQIR 328
>sp|O60291|MGRN1_HUMAN Probable E3 ubiquitin-protein ligase MGRN1 OS=Homo
sapiens GN=MGRN1 PE=1 SV=2
Length = 552
Score = 124 bits (311), Expect = 2e-027
Identities = 102/312 (32%), Positives = 147/312 (47%), Gaps = 21/312 (6%)
Frame = -3
Query: 1221 HPPPQINYGSYGYNYNPNPQQQQPPPYFYNGWNNTMMRPVFYGPAPV---VVDQQPPQAL 1051
+PP NY + + P + G N M F G PV V P + +
Sbjct: 25 YPPKSGNYFASHFFMGGEKFDTPHPEGYLFGEN---MDLNFLGSRPVQFPYVTPAPHEPV 81
Query: 1050 VEHQSAKKVRND---VNVHKDTVRLESDDLNPGYHLVS--FLFDAVFDGSFTIIFFAKEE 886
+S +R D + +KD ++D + L S F FDA + TI A EE
Sbjct: 82 KTLRSLVNIRKDSLRLVRYKDDADSPTEDGDKPRVLYSLEFTFDADARVAITIYCQASEE 141
Query: 885 ---ENCTIVPHYPEAFRPTKVPFQKGTAQKFIQPSGTGTDLGFFSLDDLSSPSPEEVYPL 715
P P + + V +++G +Q+F PS D + D+L+ V+P+
Sbjct: 142 FLNGRAVYSPKSP-SLQSETVHYKRGVSQQFSLPS-FKIDFSEWKDDELNFDLDRGVFPV 199
Query: 714 VISAETVISPSSGSEEPLVHKQVTHACLEKADGDGSFKVKVVKQILWIEGARYELRELYG 535
VI A + E H V A EK DGSF VK +KQ ++ Y L+E+YG
Sbjct: 200 VIQA---VVDEGDVVEVTGHAHVLLAAFEK-HMDGSFSVKPLKQKQIVDRVSYLLQEIYG 255
Query: 534 IDNSTAQDDVASGLEDS-GDKECVICLTEPKDTAVMPCRHLCLCSDCAKELRFQSNKCPI 358
I+N Q+ S E+S ECV+CL++ +DT ++PCRHLCLC+ CA LR+Q+N CPI
Sbjct: 256 IENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCTSCADTLRYQANNCPI 315
Query: 357 CRQPIDELLMIK 322
CR P LL I+
Sbjct: 316 CRLPFRALLQIR 327
>sp|Q9D074|MGRN1_MOUSE Probable E3 ubiquitin-protein ligase MGRN1 OS=Mus
musculus GN=Mgrn1 PE=1 SV=2
Length = 532
Score = 124 bits (309), Expect = 3e-027
Identities = 99/311 (31%), Positives = 143/311 (45%), Gaps = 19/311 (6%)
Frame = -3
Query: 1221 HPPPQINYGSYGYNYNPNPQQQQPPPYFYNGWNNTMMRPVFYGPAPV---VVDQQPPQAL 1051
+PP NY + + P + G N M F G PV V P + +
Sbjct: 25 YPPKSGNYFASHFFMGGEKFDTPHPEGYLFGEN---MDLNFLGSRPVQFPYVTPAPHEPV 81
Query: 1050 VEHQSAKKVRND----VNVHKDTVRLESDDLNPG-YHLVSFLFDAVFDGSFTIIFFAKEE 886
+S +R D V +D D P + + F FDA + TI A EE
Sbjct: 82 KTLRSLVNIRKDSLRLVRYKEDADSPTEDGEKPRVLYSLEFTFDADARVAITIYCQAVEE 141
Query: 885 --ENCTIVPHYPEAFRPTKVPFQKGTAQKFIQPSGTGTDLGFFSLDDLSSPSPEEVYPLV 712
+ + + V +++G +Q+F PS D + D+L+ V+P+V
Sbjct: 142 LVNGVAVYSCKNPSLQSETVHYKRGVSQQFSLPS-FKIDFSEWKDDELNFDLDRGVFPVV 200
Query: 711 ISAETVISPSSGSEEPLVHKQVTHACLEKADGDGSFKVKVVKQILWIEGARYELRELYGI 532
I A + E H V A EK DGSF VK +KQ ++ Y L+E+YGI
Sbjct: 201 IQA---VVDEGDVVEVTGHAHVLLAAFEK-HVDGSFSVKPLKQKQIVDRVSYLLQEIYGI 256
Query: 531 DNSTAQDDVASGLEDS-GDKECVICLTEPKDTAVMPCRHLCLCSDCAKELRFQSNKCPIC 355
+N Q+ S E+S ECV+CL++ +DT ++PCRHLCLC+ CA LR+Q+N CPIC
Sbjct: 257 ENKNNQETKPSDDENSDNSSECVVCLSDLRDTLILPCRHLCLCTSCADTLRYQANNCPIC 316
Query: 354 RQPIDELLMIK 322
R P LL I+
Sbjct: 317 RLPFRALLQIR 327
>sp|Q1A1A1|FOXG1_CERSI Forkhead box protein G1 OS=Ceratotherium simum GN=FOXG1
PE=3 SV=1
Length = 486
Score = 55 bits (132), Expect = 9e-007
Identities = 29/70 (41%), Positives = 35/70 (50%), Gaps = 5/70 (7%)
Frame = -3
Query: 1410 SNRRRNNHHRRYHHHLPPPP---PYYYSDQPQQPPPQPPPNNEYSYTHNHLVSAPQYSLP 1240
S+ +++HH +HHH PPPP P PQQPPP P P+ PQ L
Sbjct: 42 SHHPQHHHHHHHHHHHPPPPAPQPPPPPPPPQQPPPAPQPSQARGVPAADDDKGPQQLLL 101
Query: 1239 PPPSQPHPPP 1210
PPP P PPP
Sbjct: 102 PPP--PPPPP 109
>sp|Q1A1A2|FOXG1_EQUBU Forkhead box protein G1 OS=Equus burchelli GN=FOXG1 PE=3
SV=1
Length = 488
Score = 55 bits (132), Expect = 9e-007
Identities = 27/70 (38%), Positives = 34/70 (48%), Gaps = 4/70 (5%)
Frame = -3
Query: 1410 SNRRRNNHHRRYHHHLPPPPPYYYSDQPQQPPPQPPPNNEYSYTHNHLVS----APQYSL 1243
S+ +++HH +HHH PPPP PQQ PP PP + S + PQ L
Sbjct: 42 SHHPQHHHHHHHHHHHPPPPAPQPPPPPQQQPPPPPQAPQPSQARGVPAADDDKGPQQLL 101
Query: 1242 PPPPSQPHPP 1213
PPP P PP
Sbjct: 102 LPPPPPPQPP 111
>sp|Q1A1A5|FOXG1_CERPY Forkhead box protein G1 OS=Cercopithecus pygerythrus
GN=FOXG1 PE=3 SV=1
Length = 489
Score = 55 bits (130), Expect = 2e-006
Identities = 30/73 (41%), Positives = 37/73 (50%), Gaps = 8/73 (10%)
Frame = -3
Query: 1410 SNRRRNNHHRRYHHHLPPPPPYYYSDQPQQ--PPPQPPPNNEYSYTHNHLVS----APQY 1249
S+ +++HH +HHH PPPP PQQ PPP PPP + T + PQ
Sbjct: 42 SHHPQHHHHHHHHHHHPPPPAPQPPPPPQQQPPPPPPPPAPQPPQTRGAPAADDDKGPQQ 101
Query: 1248 SLPPPPSQPHPPP 1210
L PPP P PPP
Sbjct: 102 LLLPPP--PPPPP 112
>sp|P55316|FOXG1_HUMAN Forkhead box protein G1 OS=Homo sapiens GN=FOXG1 PE=1
SV=2
Length = 489
Score = 55 bits (130), Expect = 2e-006
Identities = 30/73 (41%), Positives = 37/73 (50%), Gaps = 8/73 (10%)
Frame = -3
Query: 1410 SNRRRNNHHRRYHHHLPPPPPYYYSDQP--QQPPPQPPPNNEYSYTHNHLVS----APQY 1249
S+ +++HH +HHH PPPP P QQPPP PPP + T + PQ
Sbjct: 42 SHHPQHHHHHHHHHHHPPPPAPQPPPPPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQ 101
Query: 1248 SLPPPPSQPHPPP 1210
L PPP P PPP
Sbjct: 102 LLLPPP--PPPPP 112
>sp|O10296|IAP1_NPVOP Apoptosis inhibitor 1 OS=Orgyia pseudotsugata multicapsid
polyhedrosis virus GN=IAP1 PE=4 SV=1
Length = 275
Score = 54 bits (129), Expect = 2e-006
Identities = 24/66 (36%), Positives = 33/66 (50%), Gaps = 3/66 (4%)
Frame = -3
Query: 522 TAQDDVASGLEDSGDKECVICLTEPKDTAVMPCRHLCLCSDCAKELRFQSNKCPICRQPI 343
TA + A S EC +CL +D ++PCRH C+C C L KCP CRQ +
Sbjct: 210 TAPGEPAPAFAGSEALECKVCLERQRDAVLLPCRHFCVCMQCYFAL---DGKCPTCRQDV 266
Query: 342 DELLMI 325
+ + I
Sbjct: 267 ADFIKI 272
>sp|Q7M3S9|RNGB_DICDI RING finger protein B OS=Dictyostelium discoideum GN=rngB
PE=2 SV=2
Length = 943
Score = 53 bits (126), Expect = 5e-006
Identities = 22/44 (50%), Positives = 28/44 (63%), Gaps = 4/44 (9%)
Frame = -3
Query: 471 CVICLTEPKDTAVMPCRHLCLCSDCAKELRFQSNKCPICRQPID 340
CVIC + P + ++PCRH LCSDC +L KCPICR I+
Sbjct: 897 CVICASNPPNIVLLPCRHSSLCSDCCSKL----TKCPICRSHIE 936
>sp|Q1A1A6|FOXG1_CEBCA Forkhead box protein G1 OS=Cebus capucinus GN=FOXG1 PE=3
SV=1
Length = 489
Score = 53 bits (125), Expect = 6e-006
Identities = 29/73 (39%), Positives = 36/73 (49%), Gaps = 8/73 (10%)
Frame = -3
Query: 1410 SNRRRNNHHRRYHHHLPPPPPYYYSDQP--QQPPPQPPPNNEYSYTHNHLVS----APQY 1249
S+ +++HH +HHH PPPP P QQPPP PPP + + PQ
Sbjct: 42 SHHPQHHHHHHHHHHHPPPPAPQPPPPPQQQQPPPPPPPAPQPPQARGAPAADDDKGPQQ 101
Query: 1248 SLPPPPSQPHPPP 1210
L PPP P PPP
Sbjct: 102 LLLPPP--PPPPP 112
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 145,789,284,539
Number of Sequences: 518415
Number of Extensions: 145789284539
Number of Successful Extensions: 911502421
Number of sequences better than 0.0: 0
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