BLASTX 7.6.2
Query= UN37996 /QuerySize=1275
(1274 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q55BK0|UFD1_DICDI Ubiquitin fusion degradation protein 1 homo... 241 1e-062
sp|Q9ES53|UFD1_RAT Ubiquitin fusion degradation protein 1 homolo... 227 2e-058
sp|Q92890|UFD1_HUMAN Ubiquitin fusion degradation protein 1 homo... 225 5e-058
sp|P70362|UFD1_MOUSE Ubiquitin fusion degradation protein 1 homo... 225 7e-058
sp|Q9VTF9|UFD1_DROME Ubiquitin fusion degradation protein 1 homo... 206 4e-052
sp|O42915|UFD1_SCHPO Ubiquitin fusion degradation protein 1 OS=S... 188 1e-046
sp|P53044|UFD1_YEAST Ubiquitin fusion degradation protein 1 OS=S... 179 3e-044
sp|Q19584|UFD1_CAEEL Ubiquitin fusion degradation protein 1 homo... 165 9e-040
>sp|Q55BK0|UFD1_DICDI Ubiquitin fusion degradation protein 1 homolog
OS=Dictyostelium discoideum GN=ufd1 PE=3 SV=1
Length = 330
Score = 241 bits (614), Expect = 1e-062
Identities = 125/308 (40%), Positives = 187/308 (60%), Gaps = 16/308 (5%)
Frame = -3
Query: 1029 YRCYPVTFI--EKAHLDKGDKIIMPPSALNRLASLHIEYPMLFQLSNESVGKITHCGVLE 856
++ +P++F+ EK L+ G KI++PPSALN L+ L+I+YPMLF++SN GK +HCGVLE
Sbjct: 29 FKAFPISFLPKEKHSLESGGKILLPPSALNALSRLNIQYPMLFEISNPISGKKSHCGVLE 88
Query: 855 FTADEGLVYFPYWMMQNMSLQEGDIVRIKNMSLVKGTYIKLQPHTQDFLDITNPKAILET 676
F A+EG+ Y P WMMQN+ L+EG+ + IKN +L KGT++K+QP T +F+DI+NPKA+LE
Sbjct: 89 FIAEEGICYLPLWMMQNLQLKEGEFIDIKNATLAKGTFVKIQPRTSNFIDISNPKAVLEN 148
Query: 675 TLRSYSCLTTGDTIMVPYNNKQYFINVVEAKPSSAVSIIETDCEVDFAPPLDYKEPEKPQ 496
+LR ++ LT D IM+ YNN +Y++ VVE KP++A+SIIE D VDFAPP+D KE P
Sbjct: 149 SLRKFATLTKDDEIMIDYNNTKYYLKVVELKPANAISIIEADVSVDFAPPMDSKEATSPS 208
Query: 495 NLTPLKKRTRQVEEEEPASKVPKFTPFTGS*KRLDGKTQTESTGQEETKQEEKPTEK--- 325
+P SK F P + S K + G + + ++ +++P K
Sbjct: 209 TSSP-------GSHVSGPSKGLTFGPASTSAKPIPGGKKKKDESDSDSDSDDEPKFKAFA 261
Query: 324 GKDEEKLSSITPPQKSGKLVFGSNSKQTSKANVKVDPKNVEQESS----TKSDEAKFKVF 157
G + P + +N+ + N + N +S TK+++ KFK F
Sbjct: 262 GTGARLDGKVGTPLGTSPKTLNTNNNNNNNNNNNNNNNNNNNNNSNNNNTKNEDTKFKSF 321
Query: 156 TGKKYSLK 133
+GK +SLK
Sbjct: 322 SGKGHSLK 329
>sp|Q9ES53|UFD1_RAT Ubiquitin fusion degradation protein 1 homolog OS=Rattus
norvegicus GN=Ufd1l PE=1 SV=1
Length = 307
Score = 227 bits (577), Expect = 2e-058
Identities = 125/272 (45%), Positives = 171/272 (62%), Gaps = 22/272 (8%)
Frame = -3
Query: 1029 YRCYPVTFI----EKAHLDKGDKIIMPPSALNRLASLHIEYPMLFQLSNESVGKITHCGV 862
YRC+ V+ + +++ ++KG KIIMPPSAL++L+ L+I YPMLF+L+N++ ++THCGV
Sbjct: 23 YRCFSVSMLAGPNDRSDVEKGGKIIMPPSALDQLSRLNITYPMLFKLTNKNSDRMTHCGV 82
Query: 861 LEFTADEGLVYFPYWMMQNMSLQEGDIVRIKNMSLVKGTYIKLQPHTQDFLDITNPKAIL 682
LEF ADEG+ Y P+WMMQN+ L+EG +V++++++L TY K QP + DFLDITNPKA+L
Sbjct: 83 LEFVADEGICYLPHWMMQNLLLEEGGLVQVESVNLQVATYSKFQPQSPDFLDITNPKAVL 142
Query: 681 ETTLRSYSCLTTGDTIMVPYNNKQYFINVVEAKPSSAVSIIETDCEVDFAPPLDYKEPEK 502
E LR+++CLTTGD I + YN K Y + V+E KP AVSIIE D VDF PL YKEPE+
Sbjct: 143 ENALRNFACLTTGDVIAINYNEKIYELRVMETKPDKAVSIIECDMNVDFDAPLGYKEPER 202
Query: 501 PQNLTPLKKRTRQVEEEEPASKVP---KFTPFTGS*KRLDGKTQTESTGQEETKQEEKPT 331
P + +E E S F F+GS RLDGK + G E + KP
Sbjct: 203 P------VQHEESIEGEADHSGYAGEVGFRAFSGSGNRLDGKKK----GVEPSPSPIKP- 251
Query: 330 EKGKDEEKLSSITPPQKSGKLVFGSNSKQTSK 235
+ K K GK+ F NS+ K
Sbjct: 252 ----GDIKRGIPNYEFKLGKITFIRNSRPMVK 279
>sp|Q92890|UFD1_HUMAN Ubiquitin fusion degradation protein 1 homolog OS=Homo
sapiens GN=UFD1L PE=1 SV=3
Length = 307
Score = 225 bits (573), Expect = 5e-058
Identities = 126/272 (46%), Positives = 170/272 (62%), Gaps = 33/272 (12%)
Frame = -3
Query: 1029 YRCYPVTFI----EKAHLDKGDKIIMPPSALNRLASLHIEYPMLFQLSNESVGKITHCGV 862
YRC+ V+ + +++ ++KG KIIMPPSAL++L+ L+I YPMLF+L+N++ ++THCGV
Sbjct: 23 YRCFSVSMLAGPNDRSDVEKGGKIIMPPSALDQLSRLNITYPMLFKLTNKNSDRMTHCGV 82
Query: 861 LEFTADEGLVYFPYWMMQNMSLQEGDIVRIKNMSLVKGTYIKLQPHTQDFLDITNPKAIL 682
LEF ADEG+ Y P+WMMQN+ L+EG +V++++++L TY K QP + DFLDITNPKA+L
Sbjct: 83 LEFVADEGICYLPHWMMQNLLLEEGGLVQVESVNLQVATYSKFQPQSPDFLDITNPKAVL 142
Query: 681 ETTLRSYSCLTTGDTIMVPYNNKQYFINVVEAKPSSAVSIIETDCEVDFAPPLDYKEPEK 502
E LR+++CLTTGD I + YN K Y + V+E KP AVSIIE D VDF PL YKEPE
Sbjct: 143 ENALRNFACLTTGDVIAINYNEKIYELRVMETKPDKAVSIIECDMNVDFDAPLGYKEPE- 201
Query: 501 PQNLTPLKKRTRQVEEEEPASKVPK---------FTPFTGS*KRLDGKTQTESTGQEETK 349
RQV+ EE F F+GS RLDGK + G E +
Sbjct: 202 -----------RQVQHEESTEGEADHSGYAGELGFRAFSGSGNRLDGKKK----GVEPSP 246
Query: 348 QEEKPTEKGKD----EEKLSSITPPQKSGKLV 265
KP + + E KL IT + S LV
Sbjct: 247 SPIKPGDIKRGIPNYEFKLGKITFIRNSRPLV 278
>sp|P70362|UFD1_MOUSE Ubiquitin fusion degradation protein 1 homolog OS=Mus
musculus GN=Ufd1l PE=1 SV=1
Length = 307
Score = 225 bits (572), Expect = 7e-058
Identities = 123/266 (46%), Positives = 171/266 (64%), Gaps = 21/266 (7%)
Frame = -3
Query: 1029 YRCYPVTFI----EKAHLDKGDKIIMPPSALNRLASLHIEYPMLFQLSNESVGKITHCGV 862
YRC+ V+ + +++ ++KG KIIMPPSAL++L+ L+I YPMLF+L+N++ ++THCGV
Sbjct: 23 YRCFSVSMLAGPNDRSDVEKGGKIIMPPSALDQLSRLNITYPMLFKLTNKNSDRMTHCGV 82
Query: 861 LEFTADEGLVYFPYWMMQNMSLQEGDIVRIKNMSLVKGTYIKLQPHTQDFLDITNPKAIL 682
LEF ADEG+ Y P+WMMQN+ L+EG +V++++++L TY K QP + DFLDITNPKA+L
Sbjct: 83 LEFVADEGICYLPHWMMQNLLLEEGGLVQVESVNLQVATYSKFQPQSPDFLDITNPKAVL 142
Query: 681 ETTLRSYSCLTTGDTIMVPYNNKQYFINVVEAKPSSAVSIIETDCEVDFAPPLDYKEPEK 502
E LR+++C+TTGD I + YN K Y + V+E KP AVSIIE D VDF PL YKEP++
Sbjct: 143 ENALRNFACMTTGDVIAINYNEKIYELRVMETKPDKAVSIIECDMNVDFDAPLGYKEPKR 202
Query: 501 PQNLTPLKKRTRQVEEEEPASKVP---KFTPFTGS*KRLDGKTQTESTGQEETKQEEKPT 331
P + +E E S F F+GS RLDGK + G E + KP
Sbjct: 203 P------VQHEESIEGEADHSGYAGEVGFRAFSGSGNRLDGKKK----GVEPSPSPIKPG 252
Query: 330 EKGKD----EEKLSSITPPQKSGKLV 265
+ + E KL IT + S LV
Sbjct: 253 DIKRGIPNYEFKLGKITFIRNSRPLV 278
>sp|Q9VTF9|UFD1_DROME Ubiquitin fusion degradation protein 1 homolog
OS=Drosophila melanogaster GN=Ufd1-like PE=1 SV=1
Length = 316
Score = 206 bits (522), Expect = 4e-052
Identities = 113/246 (45%), Positives = 153/246 (62%), Gaps = 10/246 (4%)
Frame = -3
Query: 1035 AVYRCYPVTFI---EKAHLDKGDKIIMPPSALNRLASLHIEYPMLFQLSNESVGKITHCG 865
A Y+C+ V+ + E+ ++KG KIIMPPSAL+ L L++EYPMLF+L+N + +H G
Sbjct: 19 ANYKCFSVSMLPGNERTDVEKGGKIIMPPSALDTLTRLNVEYPMLFKLTNVKKSRSSHAG 78
Query: 864 VLEFTADEGLVYFPYWMMQNMSLQEGDIVRIKNMSLVKGTYIKLQPHTQDFLDITNPKAI 685
VLEF ADEG Y P+WMM+N+ L EGDI+ I+++SL T+ K QPH+ DFLDITNPKA+
Sbjct: 79 VLEFVADEGKCYLPHWMMENLLLGEGDILNIESVSLPVATFSKFQPHSTDFLDITNPKAV 138
Query: 684 LETTLRSYSCLTTGDTIMVPYNNKQYFINVVEAKPSSAVSIIETDCEVDFAPPLDYKEPE 505
LE LR+++CLT GD I + YN K Y + V+E KP +AVSIIE D V+F P+ YK+
Sbjct: 139 LENALRNFACLTRGDVIAIKYNKKVYELCVLETKPGNAVSIIECDMNVEFEAPVGYKDHS 198
Query: 504 KPQNLTPLKKRTRQVEEEEPASKVPKF-----TPFTGS*KRLDGKTQTESTGQEETKQEE 340
+ Q ++ E A F GS RLDGK + ES Q ET +
Sbjct: 199 ETQASGSGQQGAAGTVGGEIAGATNAILEEVVETFKGSGVRLDGKKKKES--QLETPVVK 256
Query: 339 KPTEKG 322
K +G
Sbjct: 257 KVLARG 262
>sp|O42915|UFD1_SCHPO Ubiquitin fusion degradation protein 1
OS=Schizosaccharomyces pombe GN=ufd1 PE=2 SV=4
Length = 342
Score = 188 bits (475), Expect = 1e-046
Identities = 91/189 (48%), Positives = 130/189 (68%), Gaps = 9/189 (4%)
Frame = -3
Query: 1029 YRCYPVTFI---EKAHLDKGDKIIMPPSALNRLASLHIEYPMLFQLSNESVGKITHCGVL 859
YRCYPV I E+ +++ G K+I+PPSAL +L+ L++ YPMLF NE+ K TH GVL
Sbjct: 36 YRCYPVAMIPGEERPNVNYGGKVILPPSALEKLSRLNVSYPMLFDFENEAAEKKTHGGVL 95
Query: 858 EFTADEGLVYFPYWMMQNMSLQEGDIVRIKNMSLVKGTYIKLQPHTQDFLDITNPKAILE 679
EF A+EG VY PYWMM +SL+ GD+VR+ N + +G+Y+KLQP + +FLDIT+ +A+LE
Sbjct: 96 EFIAEEGRVYLPYWMMTTLSLEPGDLVRVINTDIAQGSYVKLQPQSVNFLDITDHRAVLE 155
Query: 678 TTLRSYSCLTTGDTIMVPYNNKQYFINVVEAKPSSA---VSIIETDCEVDFAPPLDYKE- 511
LR++S LT D + YN++ Y I V++ +P + VS++ETD VDF PP+ Y+E
Sbjct: 156 NALRNFSTLTKSDIFEILYNDQVYQIKVIDVQPDDSRHVVSVVETDLVVDFDPPIGYEES 215
Query: 510 --PEKPQNL 490
K QN+
Sbjct: 216 LQKNKQQNI 224
>sp|P53044|UFD1_YEAST Ubiquitin fusion degradation protein 1 OS=Saccharomyces
cerevisiae GN=UFD1 PE=1 SV=1
Length = 361
Score = 179 bits (454), Expect = 3e-044
Identities = 84/182 (46%), Positives = 123/182 (67%), Gaps = 7/182 (3%)
Frame = -3
Query: 1029 YRCYPVTF----IEKAHLDKGDKIIMPPSALNRLASLHIEYPMLFQLSNESVGKITHCGV 862
+RCYP+ I K + G KI +PPSAL++L+ L+I YPMLF+L+ G++TH GV
Sbjct: 25 FRCYPIAMMNDRIRKDDANFGGKIFLPPSALSKLSMLNIRYPMLFKLTANETGRVTHGGV 84
Query: 861 LEFTADEGLVYFPYWMMQNMSLQEGDIVRIKNMSLVKGTYIKLQPHTQDFLDITNPKAIL 682
LEF A+EG VY P WMM+ + +Q G +++I + + G ++KL+P + DFLDI++PKA+L
Sbjct: 85 LEFIAEEGRVYLPQWMMETLGIQPGSLLQISSTDVPLGQFVKLEPQSVDFLDISDPKAVL 144
Query: 681 ETTLRSYSCLTTGDTIMVPYNNKQYFINVVEAKP---SSAVSIIETDCEVDFAPPLDYKE 511
E LR++S LT D I + YN K + I ++E KP S ++ +IETD DFAPP+ Y E
Sbjct: 145 ENVLRNFSTLTVDDVIEISYNGKTFKIKILEVKPESSSKSICVIETDLVTDFAPPVGYVE 204
Query: 510 PE 505
P+
Sbjct: 205 PD 206
>sp|Q19584|UFD1_CAEEL Ubiquitin fusion degradation protein 1 homolog
OS=Caenorhabditis elegans GN=ufd-1 PE=1 SV=1
Length = 342
Score = 165 bits (416), Expect = 9e-040
Identities = 81/171 (47%), Positives = 115/171 (67%), Gaps = 2/171 (1%)
Frame = -3
Query: 996 AHLDKGDKIIMPPSALNRLASLHIEYPMLFQLSNESVGKITHCGVLEFTADEGLVYFPYW 817
+ ++ G KI++P SALN L +I PMLF+L+N +V ++THCGVLEF+A EG P W
Sbjct: 42 SEINYGGKILLPSSALNLLMQYNIPMPMLFKLTNMAVQRVTHCGVLEFSAPEGQAILPLW 101
Query: 816 MMQNMSLQEGDIVRIKNMSLVKGTYIKLQPHTQDFLDITNPKAILETTLRSYSCLTTGDT 637
MMQ + L +GD +RI++ +L K T+ KL+P + +FL+ITNPKA+LE LR Y+CLT D
Sbjct: 102 MMQQLGLDDGDTIRIESATLPKATFAKLKPMSLEFLNITNPKAVLEVELRKYACLTKNDR 161
Query: 636 IMVPYNNKQYFINVVEAKPSSAVSIIETDCEVDFAPPLDYKEPEKPQNLTP 484
I Y + VV+ KP+++V IIE D +DF PP Y E+P+ +TP
Sbjct: 162 IPTSYAGQTLEFLVVDLKPANSVCIIECDVNLDFDPPEGY--VEQPRQVTP 210
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 148,698,637,428
Number of Sequences: 518415
Number of Extensions: 148698637428
Number of Successful Extensions: 919591668
Number of sequences better than 0.0: 0
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