BLASTX 7.6.2
Query= UN38259 /QuerySize=1253
(1252 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9ERI6|RDH14_MOUSE Retinol dehydrogenase 14 OS=Mus musculus G... 176 5e-043
sp|Q9HBH5|RDH14_HUMAN Retinol dehydrogenase 14 OS=Homo sapiens G... 175 6e-043
sp|Q8BYK4|RDH12_MOUSE Retinol dehydrogenase 12 OS=Mus musculus G... 175 8e-043
sp|Q8NBN7|RDH13_HUMAN Retinol dehydrogenase 13 OS=Homo sapiens G... 168 8e-041
sp|Q96NR8|RDH12_HUMAN Retinol dehydrogenase 12 OS=Homo sapiens G... 166 5e-040
sp|Q8CEE7|RDH13_MOUSE Retinol dehydrogenase 13 OS=Mus musculus G... 164 1e-039
sp|Q8N5I4|DHRSX_HUMAN Dehydrogenase/reductase SDR family member ... 157 2e-037
sp|Q8VBZ0|DHRSX_MOUSE Dehydrogenase/reductase SDR family member ... 149 6e-035
sp|Q803A8|WWOX_DANRE WW domain-containing oxidoreductase OS=Dani... 134 1e-030
sp|O74959|YJCD_SCHPO Uncharacterized oxidoreductase C736.13 OS=S... 117 2e-025
sp|Q9VLU5|WWOX_DROME WW domain-containing oxidoreductase OS=Dros... 109 4e-023
sp|P59837|RDH12_BOVIN Retinol dehydrogenase 12 OS=Bos taurus GN=... 95 1e-018
sp|Q9QYF1|RDH11_MOUSE Retinol dehydrogenase 11 OS=Mus musculus G... 94 1e-018
sp|Q8TC12|RDH11_HUMAN Retinol dehydrogenase 11 OS=Homo sapiens G... 94 2e-018
sp|Q91WL8|WWOX_MOUSE WW domain-containing oxidoreductase OS=Mus ... 83 3e-015
sp|Q5F389|WWOX_CHICK WW domain-containing oxidoreductase OS=Gall... 78 1e-013
sp|Q9NZC7|WWOX_HUMAN WW domain-containing oxidoreductase OS=Homo... 77 3e-013
sp|Q5R9W5|WWOX_PONAB WW domain-containing oxidoreductase OS=Pong... 77 3e-013
sp|Q08651|YO246_YEAST Uncharacterized oxidoreductase YOR246C OS=... 65 1e-009
>sp|Q9ERI6|RDH14_MOUSE Retinol dehydrogenase 14 OS=Mus musculus GN=Rdh14 PE=1
SV=1
Length = 334
Score = 176 bits (444), Expect = 5e-043
Identities = 98/237 (41%), Positives = 147/237 (62%), Gaps = 13/237 (5%)
Frame = +2
Query: 290 NARVTLIHLDLSSFKSIKAFVRDFHALHLPLNILINNAGVMFCPYQLSEDGIELQFATNH 469
+ ++ + LDL+S +S++AF ++ L++LINNAGV CPY +EDG E+QF NH
Sbjct: 104 DGQLVVKELDLASLRSVRAFCQELLQEEPRLDVLINNAGVFHCPYTKTEDGFEMQFGVNH 163
Query: 470 MGHFLLTNLPLDTMKNTAKTSGVEGRILNLSSIAHIYTYQEGIQFDSINDICSYSDKRAY 649
+GHFLLTNL L +K++A + RI+ +SS +Y Y E I F+ +N SY+ Y
Sbjct: 164 LGHFLLTNLLLGLLKSSAPS-----RIVVVSS--KLYKYGE-INFEDLNSEQSYNKSFCY 215
Query: 650 GQSKLANILHANKLSRQLQEEGVNITVNSVHPGLILTNLFQHTALLMRFLKFFSFYLW-- 823
+SKLANIL +L+R+L EG N+TVN +HPG++ TNL +H + + F+ W
Sbjct: 216 SRSKLANILFTRELARRL--EGTNVTVNVLHPGIVRTNLGRHIHIPLLARPLFNLVSWAF 273
Query: 824 -KNIPQGAATTCYVALHPSLKEVTGKYFADCNEVTPSKLARDETLAQKLWDFSVKLI 991
K +GA T+ Y+A P ++ V+G+YF DC E A DE++A+KLWD S ++
Sbjct: 274 FKTPLEGAQTSIYLACSPDVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMV 330
>sp|Q9HBH5|RDH14_HUMAN Retinol dehydrogenase 14 OS=Homo sapiens GN=RDH14 PE=1
SV=1
Length = 336
Score = 175 bits (443), Expect = 6e-043
Identities = 97/229 (42%), Positives = 143/229 (62%), Gaps = 13/229 (5%)
Frame = +2
Query: 314 LDLSSFKSIKAFVRDFHALHLPLNILINNAGVMFCPYQLSEDGIELQFATNHMGHFLLTN 493
LDL+S +S++AF ++ L++LINNAG+ CPY +EDG E+QF NH+GHFLLTN
Sbjct: 114 LDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGVNHLGHFLLTN 173
Query: 494 LPLDTMKNTAKTSGVEGRILNLSSIAHIYTYQEGIQFDSINDICSYSDKRAYGQSKLANI 673
L L +K++A + RI+ +SS +Y Y + I FD +N SY+ Y +SKLANI
Sbjct: 174 LLLGLLKSSAPS-----RIVVVSS--KLYKYGD-INFDDLNSEQSYNKSFCYSRSKLANI 225
Query: 674 LHANKLSRQLQEEGVNITVNSVHPGLILTNLFQHTALLMRFLKFFSFYLW---KNIPQGA 844
L +L+R+L EG N+TVN +HPG++ TNL +H + + F+ W K +GA
Sbjct: 226 LFTRELARRL--EGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKTPVEGA 283
Query: 845 ATTCYVALHPSLKEVTGKYFADCNEVTPSKLARDETLAQKLWDFSVKLI 991
T+ Y+A P ++ V+G+YF DC E A DE++A+KLWD S ++
Sbjct: 284 QTSIYLASSPEVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMV 332
>sp|Q8BYK4|RDH12_MOUSE Retinol dehydrogenase 12 OS=Mus musculus GN=Rdh12 PE=2
SV=1
Length = 316
Score = 175 bits (442), Expect = 8e-043
Identities = 100/242 (41%), Positives = 148/242 (61%), Gaps = 11/242 (4%)
Frame = +2
Query: 266 TEILRQNANARVTLIHLDLSSFKSIKAFVRDFHALHLPLNILINNAGVMFCPYQLSEDGI 445
+EI N++V + LDLS KSI+AF F A L+ILINNAGVM CPY + DG
Sbjct: 81 SEIRADTKNSQVLVRKLDLSDTKSIRAFAERFLAEEKKLHILINNAGVMMCPYSKTTDGF 140
Query: 446 ELQFATNHMGHFLLTNLPLDTMKNTAKTSGVEGRILNLSSIAHIYTYQEGIQFDSINDIC 625
E F NH+GHFLLT L L+ +K +A R++NLSSIAH+ I+F +
Sbjct: 141 ETHFGVNHLGHFLLTYLLLERLKESA-----PARVVNLSSIAHLI---GKIRFHDLQGQK 192
Query: 626 SYSDKRAYGQSKLANILHANKLSRQLQEEGVNITVNSVHPGLILTNLFQHTALLMRFLKF 805
Y AYG SKLAN+L +L+++LQ G +T +VHPG++L+ + +++ LL +
Sbjct: 193 RYCSAFAYGHSKLANLLFTRELAKRLQ--GTGVTAYAVHPGVVLSEITRNSYLLCLLWRL 250
Query: 806 FSFYLWKNIPQGAATTCYVALHPSLKEVTGKYFADCNEVTPSKLARDETLAQKLWDFSVK 985
FS + +K+ QGA T+ + AL L+ ++GKYF+DC + S AR++ A++LW+ S +
Sbjct: 251 FSPF-FKSTSQGAQTSLHCALAEDLEPLSGKYFSDCKRMWVSSRARNKKTAERLWNVSCE 309
Query: 986 LI 991
L+
Sbjct: 310 LL 311
>sp|Q8NBN7|RDH13_HUMAN Retinol dehydrogenase 13 OS=Homo sapiens GN=RDH13 PE=1
SV=2
Length = 331
Score = 168 bits (425), Expect = 8e-041
Identities = 107/251 (42%), Positives = 149/251 (59%), Gaps = 20/251 (7%)
Frame = +2
Query: 257 DSKTEILRQNANARVTLIHLDLSSFKSIKAFVRDFHALHLPLNILINNAGVMFCPYQLSE 436
D + E L + NAR HLDL+S KSI+ F ++ILINNAGVM CP+ +E
Sbjct: 81 DIRGETLNHHVNAR----HLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTE 136
Query: 437 DGIELQFATNHMGHFLLTNLPLDTMKNTAKTSGVEGRILNLSSIAHIYTYQEGIQFDSIN 616
DG E+QF NH+GHFLLTNL LD +K +A + RI+NLSS+AH+ + I FD +N
Sbjct: 137 DGFEMQFGVNHLGHFLLTNLLLDKLKASAPS-----RIINLSSLAHVAGH---IDFDDLN 188
Query: 617 -DICSYSDKRAYGQSKLANILHANKLSRQLQEEGVNITVNSVHPGLILTNLFQHTALLMR 793
Y+ K AY QSKLA +L +LSR+LQ GV TVN++HPG+ T L +HT +
Sbjct: 189 WQTRKYNTKAAYCQSKLAIVLFTKELSRRLQGSGV--TVNALHPGVARTELGRHTGIHGS 246
Query: 794 FLKFFS----FYLWKNIPQGAA-TTCYVALHPSLKEVTGKYFADCNEVTPSKLARDETLA 958
+ F+L P+ AA + Y+A+ L +V+GKYF + P+ A DE +A
Sbjct: 247 TFSSTTLGPIFWLLVKSPELAAQPSTYLAVAEELADVSGKYFDGLKQKAPAPEAEDEEVA 306
Query: 959 QKLWDFSVKLI 991
++LW S +L+
Sbjct: 307 RRLWAESARLV 317
>sp|Q96NR8|RDH12_HUMAN Retinol dehydrogenase 12 OS=Homo sapiens GN=RDH12 PE=1
SV=3
Length = 316
Score = 166 bits (418), Expect = 5e-040
Identities = 97/242 (40%), Positives = 143/242 (59%), Gaps = 11/242 (4%)
Frame = +2
Query: 266 TEILRQNANARVTLIHLDLSSFKSIKAFVRDFHALHLPLNILINNAGVMFCPYQLSEDGI 445
+EI N++V + LDLS KSI+AF F A L+ILINNAGVM CPY + DG
Sbjct: 81 SEIRVDTKNSQVLVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGF 140
Query: 446 ELQFATNHMGHFLLTNLPLDTMKNTAKTSGVEGRILNLSSIAHIYTYQEGIQFDSINDIC 625
E NH+GHFLLT L L+ +K +A R++N+SS+AH + I F +
Sbjct: 141 ETHLGVNHLGHFLLTYLLLERLKVSA-----PARVVNVSSVAH---HIGKIPFHDLQSEK 192
Query: 626 SYSDKRAYGQSKLANILHANKLSRQLQEEGVNITVNSVHPGLILTNLFQHTALLMRFLKF 805
YS AY SKLAN+L +L+++LQ G +T +VHPG++ + L +H++LL +
Sbjct: 193 RYSRGFAYCHSKLANVLFTRELAKRLQ--GTGVTTYAVHPGVVRSELVRHSSLLCLLWRL 250
Query: 806 FSFYLWKNIPQGAATTCYVALHPSLKEVTGKYFADCNEVTPSKLARDETLAQKLWDFSVK 985
FS ++ K +GA T+ + AL L+ ++GKYF+DC S AR+ A++LW+ S +
Sbjct: 251 FSPFV-KTAREGAQTSLHCALAEGLEPLSGKYFSDCKRTWVSPRARNNKTAERLWNVSCE 309
Query: 986 LI 991
L+
Sbjct: 310 LL 311
>sp|Q8CEE7|RDH13_MOUSE Retinol dehydrogenase 13 OS=Mus musculus GN=Rdh13 PE=2
SV=1
Length = 334
Score = 164 bits (415), Expect = 1e-039
Identities = 103/247 (41%), Positives = 145/247 (58%), Gaps = 16/247 (6%)
Frame = +2
Query: 269 EILRQNANARVTLIHLDLSSFKSIKAFVRDFHALHLPLNILINNAGVMFCPYQLSEDGIE 448
+I + N RV LDL+S KSI+ F R ++IL+NNA VM CP+ +EDG E
Sbjct: 81 DIRGETLNPRVRAERLDLASLKSIREFARKVIKEEERVDILVNNAAVMRCPHWTTEDGFE 140
Query: 449 LQFATNHMGHFLLTNLPLDTMKNTAKTSGVEGRILNLSSIAHIYTYQEGIQFDSIN-DIC 625
+QF N++GHFLLTNL LD +K +A + RI+NLSS+AH+ + I F+ +N +
Sbjct: 141 MQFGVNYLGHFLLTNLLLDKLKASAPS-----RIINLSSLAHVAGH---IDFEDLNWQMK 192
Query: 626 SYSDKRAYGQSKLANILHANKLSRQLQEEGVNITVNSVHPGLILTNLFQHT-----ALLM 790
Y K AY QSKLA +L +LS +LQ GV TVN++HPG+ T L +HT A
Sbjct: 193 KYDTKAAYCQSKLAVVLFTKELSHRLQGSGV--TVNALHPGVARTELGRHTGMHNSAFSG 250
Query: 791 RFLKFFSFYLWKNIPQGAATTCYVALHPSLKEVTGKYFADCNEVTPSKLARDETLAQKLW 970
L F + L+K+ A + Y+A+ L+ V+GKYF E PS A DE +A++LW
Sbjct: 251 FMLGPFFWLLFKSPQLAAQPSTYLAVAEELENVSGKYFDGLREKAPSPEAEDEEVARRLW 310
Query: 971 DFSVKLI 991
S +L+
Sbjct: 311 TESARLV 317
>sp|Q8N5I4|DHRSX_HUMAN Dehydrogenase/reductase SDR family member on chromosome X
OS=Homo sapiens GN=DHRSX PE=2 SV=2
Length = 330
Score = 157 bits (396), Expect = 2e-037
Identities = 92/252 (36%), Positives = 138/252 (54%), Gaps = 10/252 (3%)
Frame = +2
Query: 251 NGDSK-----TEILRQNANARVTLIHLDLSSFKSIKAFVRDFHALHLPLNILINNAGVMF 415
N DSK ++I + N +V ++ DL+S SI+ FV+ F +PL++LINNAGVM
Sbjct: 75 NNDSKAKQVVSKIKEETLNDKVEFLYCDLASMTSIRQFVQKFKMKKIPLHVLINNAGVMM 134
Query: 416 CPYQLSEDGIELQFATNHMGHFLLTNLPLDTMKNTAKTSGVEGRILNLSSIAHIYTYQEG 595
P + + DG E F N++GHFLLTNL LDT+K + + G R++ +SS H Y
Sbjct: 135 VPQRKTRDGFEEHFGLNYLGHFLLTNLLLDTLKESG-SPGHSARVVTVSSATH---YVAE 190
Query: 596 IQFDSINDICSYSDKRAYGQSKLANILHANKLSRQLQEEGVNITVNSVHPGLILTNLFQH 775
+ D + YS AY QSKLA +L L R L EG ++T N V PG++ T++++H
Sbjct: 191 LNMDDLQSSACYSPHAAYAQSKLALVLFTYHLQRLLAAEGSHVTANVVDPGVVNTDVYKH 250
Query: 776 TALLMRFL-KFFSFYLWKNIPQGAATTCYVALHPSLKEVTGKYFADCNEVTPSKLARDET 952
R K + L+K +GA T+ Y A+ P L+ V G Y + E + ++
Sbjct: 251 VFWATRLAKKLLGWLLFKTPDEGAWTSIYAAVTPELEGVGGHYLYNEKETKSLHVTYNQK 310
Query: 953 LAQKLWDFSVKL 988
L Q+LW S ++
Sbjct: 311 LQQQLWSKSCEM 322
>sp|Q8VBZ0|DHRSX_MOUSE Dehydrogenase/reductase SDR family member on chromosome X
homolog OS=Mus musculus GN=Dhrsx PE=2 SV=2
Length = 335
Score = 149 bits (374), Expect = 6e-035
Identities = 90/249 (36%), Positives = 133/249 (53%), Gaps = 5/249 (2%)
Frame = +2
Query: 245 NRNGDSKTEILRQNANARVTLIHLDLSSFKSIKAFVRDFHALHLPLNILINNAGVMFCPY 424
+R + + I + + R + LDL+S S++ F RDF AL LPL++L+NNAGVM P
Sbjct: 78 HRGQEVVSSIRAEMGSDRAHFLPLDLASLASVRGFARDFQALGLPLHLLVNNAGVMLEPR 137
Query: 425 QLSEDGIELQFATNHMGHFLLTNLPLDTMKNTAKTSGVEGRILNLSSIAHIYTYQEGIQF 604
+EDG E N +GHFLLT L L + + SG EGR + ++ Y +
Sbjct: 138 AETEDGFERHLGVNFLGHFLLTLLLLPAL----RASGAEGRGSRVVTVGSATHYVGTVDM 193
Query: 605 DSINDICSYSDKRAYGQSKLANILHANKLSRQLQEEGVNITVNSVHPGLILTNLFQHTAL 784
++ +YS AY QSKLA L A +L R L G +T N PG++ T L++H
Sbjct: 194 ADLHGRHAYSPYAAYAQSKLALALFALQLQRILDARGDPVTSNMADPGVVDTELYRHAGW 253
Query: 785 LMRFLK-FFSFYLWKNIPQGAATTCYVALHPSLKEVTGKYFADCNEVTPSKLARDETLAQ 961
++R K F + ++K+ +GA T Y A P L+ V G+Y D E P ARD+ L +
Sbjct: 254 VLRTAKRFLGWLVFKSPEEGAWTLVYAAAAPELEGVGGRYLRDEAEAEPLGTARDQELQR 313
Query: 962 KLWDFSVKL 988
+LW ++L
Sbjct: 314 RLWAEGLRL 322
>sp|Q803A8|WWOX_DANRE WW domain-containing oxidoreductase OS=Danio rerio GN=wwox
PE=2 SV=1
Length = 412
Score = 134 bits (337), Expect = 1e-030
Identities = 88/261 (33%), Positives = 141/261 (54%), Gaps = 14/261 (5%)
Frame = +2
Query: 242 RNRNGDSKTE--ILRQNANARVTLIHLDLSSFKSIKAFVRDFHALHLPLNILINNAGVMF 415
RN++ SK I+ + + ARV ++ LDL+S +S++ F F A LPL++L+ NA V
Sbjct: 153 RNQSRASKAASLIMGEWSKARVEVLPLDLASLRSVRQFAELFKATKLPLHVLVCNAAVCS 212
Query: 416 CPYQLSEDGIELQFATNHMGHFLLTNLPLDTMKNTAKTSGVEGRILNLSSIAHIYTYQEG 595
P++L+EDG E F H+GHFLL L D ++ +A R++ +SS +H +T
Sbjct: 213 QPWRLTEDGFESTFQICHLGHFLLVQLLQDVLRLSA-----PARVVVVSSESHRFTDLLD 267
Query: 596 IQFDSINDICSYSDKR-----AYGQSKLANILHANKLSRQLQEEGVNITVNSVHPGLILT 760
+ D+ S K AY ++KL N+L +++L R++ G I N++HPG ++
Sbjct: 268 SCGNLDLDLLSPPQKNYWSLLAYNRAKLCNLLFSSELHRRMSPHG--ICCNALHPGSMMF 325
Query: 761 NLFQHTALLMRFLKFFSFYLWKNIPQGAATTCYVALHPSLKEVTGKYFADCNEVTPSKLA 940
+ L+ L + K++ QGAATT Y A+ P L+ + G YF +C PS A
Sbjct: 326 TSIHRSWWLLTLLFSLARPFTKSMQQGAATTVYCAVAPELEGIGGMYFNNCFRCLPSPQA 385
Query: 941 RDETLAQKLWDFSVKLINSVS 1003
+D A LW+ S +L+ S
Sbjct: 386 QDPAAALSLWELSERLVQERS 406
>sp|O74959|YJCD_SCHPO Uncharacterized oxidoreductase C736.13
OS=Schizosaccharomyces pombe GN=SPCC736.13 PE=2 SV=1
Length = 339
Score = 117 bits (292), Expect = 2e-025
Identities = 81/261 (31%), Positives = 139/261 (53%), Gaps = 12/261 (4%)
Frame = +2
Query: 248 RNGDSKTEILRQ----NANARVTLIHLDLSSFKSIKAFVRDFHALHLPLNILINNAGVMF 415
RN + ++++Q ++++ + LDL F+S+ F A L+IL+NNAG+M
Sbjct: 74 RNEEKYQKVMKQIHDEVRHSKIRFLRLDLLDFESVYQAAESFIAKEEKLHILVNNAGIMN 133
Query: 416 CPYQLSEDGIELQFATNHMGHFLLTNLPLDTMKNTAKTSGV-EGRILNLSSIAHIYTYQE 592
P++L++DG ELQ TN++ H+L T L L T++ TA+ + RI++++SIA++
Sbjct: 134 PPFELTKDGYELQIQTNYLSHYLFTELLLPTLRRTAEECRPGDVRIVHVASIAYLQAPYS 193
Query: 593 GIQFDSIN-DICSYSDKRAYGQSKLANILHANKLSRQLQEEGVNITVNSVHPGLILTNL- 766
GI F +N YGQSK A IL++ L+++L++ G+ S+HPG+I T L
Sbjct: 194 GIYFPDLNLPHVLLGTFARYGQSKYAQILYSIALAKRLEKYGIYSV--SLHPGVIRTELT 251
Query: 767 -FQHTALLMRFLKFFSFYLWKNIPQGAATTCYVALHP--SLKEVTGKYFADCNEVTPSKL 937
+ T L K YL + +GA T+ Y A P S + + G YF +
Sbjct: 252 RYSPTFALKLLEKSVFQYLLLDPIRGAMTSLYAATSPEISKEHLNGAYFTAIAQRGILHR 311
Query: 938 ARDETLAQKLWDFSVKLINSV 1000
A D+ ++L+ ++ K+ +
Sbjct: 312 AHDDAFVEELYRYTHKIFEDL 332
>sp|Q9VLU5|WWOX_DROME WW domain-containing oxidoreductase OS=Drosophila
melanogaster GN=Wwox PE=2 SV=1
Length = 409
Score = 109 bits (272), Expect = 4e-023
Identities = 78/242 (32%), Positives = 125/242 (51%), Gaps = 14/242 (5%)
Frame = +2
Query: 278 RQNANARVTLIHLDLSSFKSIKAFVRDFHALHLPLNILINNAGVMFCPYQLSEDGIELQF 457
R A +R LDLSS +S++ FV + ++ LI NAGV PY + DG+E F
Sbjct: 169 RPAARSRCRFAALDLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTF 228
Query: 458 ATNHMGHFLLTNLPLDTMKNTAKTSGVEGRILNLSSIAHIYTYQEGIQFDSINDIC---- 625
+H+ HF LT L L+T+ + + RI+ LSS +H + ++ +++ +
Sbjct: 229 QVSHLSHFYLT-LQLETLFD------YKTRIIVLSSESHRFA-NLPVENLAVHHLSPPPE 280
Query: 626 SYSDKRAYGQSKLANILHANKLSRQLQEEGVNITVNSVHPGLILTNLFQHTALLMRFLKF 805
Y AY +KL N+L A +L+++ ++ G I+V S+HPG ++++ R L
Sbjct: 281 KYWSMMAYNNAKLCNVLFAQELAQRWKQRG--ISVFSLHPGNMVSSDLSRNYWFYRLLFA 338
Query: 806 FSFYLWKNIPQGAATTCYVALHPSLKEVTGKYFADCNEVTPSKLARDETLAQKLWDFSVK 985
K++ Q AAT+ Y A L ++G YF +C PSKL++ L Q+LW S
Sbjct: 339 IVRPFTKSLQQAAATSIYCATANELTGLSGLYFNNCFFCEPSKLSKSAALQQQLWKLSEN 398
Query: 986 LI 991
LI
Sbjct: 399 LI 400
>sp|P59837|RDH12_BOVIN Retinol dehydrogenase 12 OS=Bos taurus GN=RDH12 PE=2
SV=1
Length = 316
Score = 95 bits (234), Expect = 1e-018
Identities = 51/103 (49%), Positives = 65/103 (63%), Gaps = 5/103 (4%)
Frame = +2
Query: 266 TEILRQNANARVTLIHLDLSSFKSIKAFVRDFHALHLPLNILINNAGVMFCPYQLSEDGI 445
+EI N++V + LDLS KSI+AF F A L+ILINNAGVM CPY + DG
Sbjct: 81 SEIQADTKNSQVLVRKLDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMLCPYSKTADGF 140
Query: 446 ELQFATNHMGHFLLTNLPLDTMKNTAKTSGVEGRILNLSSIAH 574
E A NH+GHFLLT+L L +K +A R++NLSS+AH
Sbjct: 141 ETHLAVNHLGHFLLTHLLLGRLKESA-----PARVVNLSSVAH 178
>sp|Q9QYF1|RDH11_MOUSE Retinol dehydrogenase 11 OS=Mus musculus GN=Rdh11 PE=2
SV=2
Length = 316
Score = 94 bits (233), Expect = 1e-018
Identities = 49/102 (48%), Positives = 67/102 (65%), Gaps = 5/102 (4%)
Frame = +2
Query: 269 EILRQNANARVTLIHLDLSSFKSIKAFVRDFHALHLPLNILINNAGVMFCPYQLSEDGIE 448
EI N++V + LDL+ KSI+AF +DF A L++LINNAGVM CPY + DG E
Sbjct: 81 EIQAVTGNSQVFVRKLDLADTKSIRAFAKDFLAEEKHLHLLINNAGVMMCPYSKTADGFE 140
Query: 449 LQFATNHMGHFLLTNLPLDTMKNTAKTSGVEGRILNLSSIAH 574
+ NH+GHFLLT+L L+ +K +A + RI+NLSS+ H
Sbjct: 141 MHIGVNHLGHFLLTHLLLEKLKESAPS-----RIVNLSSLGH 177
>sp|Q8TC12|RDH11_HUMAN Retinol dehydrogenase 11 OS=Homo sapiens GN=RDH11 PE=1
SV=2
Length = 318
Score = 94 bits (231), Expect = 2e-018
Identities = 49/102 (48%), Positives = 66/102 (64%), Gaps = 5/102 (4%)
Frame = +2
Query: 269 EILRQNANARVTLIHLDLSSFKSIKAFVRDFHALHLPLNILINNAGVMFCPYQLSEDGIE 448
EI N +V + LDLS KSI+AF + F A L++LINNAGVM CPY + DG E
Sbjct: 84 EIQTTTGNQQVLVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFE 143
Query: 449 LQFATNHMGHFLLTNLPLDTMKNTAKTSGVEGRILNLSSIAH 574
+ NH+GHFLLT+L L+ +K +A + RI+N+SS+AH
Sbjct: 144 MHIGVNHLGHFLLTHLLLEKLKESAPS-----RIVNVSSLAH 180
>sp|Q91WL8|WWOX_MOUSE WW domain-containing oxidoreductase OS=Mus musculus
GN=Wwox PE=1 SV=1
Length = 414
Score = 83 bits (204), Expect = 3e-015
Identities = 46/116 (39%), Positives = 69/116 (59%), Gaps = 2/116 (1%)
Frame = +2
Query: 644 AYGQSKLANILHANKLSRQLQEEGVNITVNSVHPGLILTNLFQHTALLMRFLKFFSFYLW 823
AY +SKL NIL +N+L R+L GV T N+VHPG ++ + + + + L +
Sbjct: 292 AYNRSKLCNILFSNELHRRLSPRGV--TSNAVHPGNMMYSAIHRNSWVYKLLFTLARPFT 349
Query: 824 KNIPQGAATTCYVALHPSLKEVTGKYFADCNEVTPSKLARDETLAQKLWDFSVKLI 991
K++ QGAATT Y A+ P L+ + G YF +C PS+ A+ E A+ LW+ S +LI
Sbjct: 350 KSMQQGAATTVYCAVAPELEGLGGMYFNNCCRCLPSEEAQSEETARALWELSERLI 405
>sp|Q5F389|WWOX_CHICK WW domain-containing oxidoreductase OS=Gallus gallus
GN=WWOX PE=2 SV=2
Length = 414
Score = 78 bits (191), Expect = 1e-013
Identities = 47/116 (40%), Positives = 65/116 (56%), Gaps = 2/116 (1%)
Frame = +2
Query: 644 AYGQSKLANILHANKLSRQLQEEGVNITVNSVHPGLILTNLFQHTALLMRFLKFFSFYLW 823
AY +SKL NIL +N+L+R+L GV T NSVHPG ++ + + L +
Sbjct: 292 AYNRSKLCNILFSNELNRRLSPHGV--TSNSVHPGNMIYSSIHRNWWVYTLLFTLARPFT 349
Query: 824 KNIPQGAATTCYVALHPSLKEVTGKYFADCNEVTPSKLARDETLAQKLWDFSVKLI 991
K++ QGAATT Y A L+ + G YF +C PS AR+E A LW+ S +LI
Sbjct: 350 KSMQQGAATTVYCATAAELEGLGGMYFNNCCRCLPSAEARNELTAVALWELSERLI 405
>sp|Q9NZC7|WWOX_HUMAN WW domain-containing oxidoreductase OS=Homo sapiens
GN=WWOX PE=1 SV=1
Length = 414
Score = 77 bits (187), Expect = 3e-013
Identities = 46/116 (39%), Positives = 65/116 (56%), Gaps = 2/116 (1%)
Frame = +2
Query: 644 AYGQSKLANILHANKLSRQLQEEGVNITVNSVHPGLILTNLFQHTALLMRFLKFFSFYLW 823
AY +SKL NIL +N+L R+L GV T N+VHPG ++ + + + L +
Sbjct: 292 AYNRSKLCNILFSNELHRRLSPRGV--TSNAVHPGNMMYSNIHRSWWVYTLLFTLARPFT 349
Query: 824 KNIPQGAATTCYVALHPSLKEVTGKYFADCNEVTPSKLARDETLAQKLWDFSVKLI 991
K++ QGAATT Y A P L+ + G YF +C PS A+ E A+ LW S +LI
Sbjct: 350 KSMQQGAATTVYCAAVPELEGLGGMYFNNCCRCMPSPEAQSEETARTLWALSERLI 405
>sp|Q5R9W5|WWOX_PONAB WW domain-containing oxidoreductase OS=Pongo abelii
GN=WWOX PE=2 SV=1
Length = 414
Score = 77 bits (187), Expect = 3e-013
Identities = 45/116 (38%), Positives = 65/116 (56%), Gaps = 2/116 (1%)
Frame = +2
Query: 644 AYGQSKLANILHANKLSRQLQEEGVNITVNSVHPGLILTNLFQHTALLMRFLKFFSFYLW 823
AY +SKL N+L +N+L R+L GV T N+VHPG ++ + + + L +
Sbjct: 292 AYNRSKLCNVLFSNELHRRLSPRGV--TSNAVHPGNMMYSNIHRSWWVYTLLFTLARPFT 349
Query: 824 KNIPQGAATTCYVALHPSLKEVTGKYFADCNEVTPSKLARDETLAQKLWDFSVKLI 991
K++ QGAATT Y A P L+ + G YF +C PS A+ E A+ LW S +LI
Sbjct: 350 KSMQQGAATTVYCAAAPELEGLGGMYFNNCCRCMPSPEAQSEETARTLWALSERLI 405
>sp|Q08651|YO246_YEAST Uncharacterized oxidoreductase YOR246C OS=Saccharomyces
cerevisiae GN=YOR246C PE=1 SV=1
Length = 330
Score = 65 bits (156), Expect = 1e-009
Identities = 32/89 (35%), Positives = 53/89 (59%), Gaps = 6/89 (6%)
Frame = +2
Query: 308 IHLDLSSFKSIKAFVRDFHALHLPLNILINNAGVMFCPYQLSEDGIELQFATNHMGHFLL 487
IHLDL+ K ++ L +++L+NNAG+M P ++++DG E+Q TN++ HF+
Sbjct: 94 IHLDLTDLKCVERAALKILKLEDHIDVLVNNAGIMAVPLEMTKDGFEVQLQTNYISHFIF 153
Query: 488 TNLPLDTMKNTAKTSGVEGRILNLSSIAH 574
T L +++ GRI++LSSI H
Sbjct: 154 TMRLLPLLRH------CRGRIISLSSIGH 176
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 148,698,637,428
Number of Sequences: 518415
Number of Extensions: 148698637428
Number of Successful Extensions: 919591668
Number of sequences better than 0.0: 0
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