BLASTX 7.6.2
Query= UN38747 /QuerySize=845
(844 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8BH79|ANO10_MOUSE Anoctamin-10 OS=Mus musculus GN=Ano10 PE=2... 86 2e-016
sp|Q6PB70|ANO8_MOUSE Anoctamin-8 OS=Mus musculus GN=Ano8 PE=2 SV=3 86 2e-016
sp|Q9NW15|ANO10_HUMAN Anoctamin-10 OS=Homo sapiens GN=ANO10 PE=2... 86 3e-016
sp|Q9HCE9|ANO8_HUMAN Anoctamin-8 OS=Homo sapiens GN=ANO8 PE=2 SV=3 83 2e-015
sp|Q9BYT9|ANO3_HUMAN Anoctamin-3 OS=Homo sapiens GN=ANO3 PE=2 SV=2 78 8e-014
sp|A2AHL1|ANO3_MOUSE Anoctamin-3 OS=Mus musculus GN=Ano3 PE=2 SV=1 78 8e-014
sp|Q6P9J9|ANO6_MOUSE Anoctamin-6 OS=Mus musculus GN=Ano6 PE=1 SV=1 77 2e-013
sp|Q4KMQ2|ANO6_HUMAN Anoctamin-6 OS=Homo sapiens GN=ANO6 PE=1 SV=2 76 2e-013
sp|A6QLE6|ANO4_BOVIN Anoctamin-4 OS=Bos taurus GN=ANO4 PE=2 SV=1 75 4e-013
sp|Q32M45|ANO4_HUMAN Anoctamin-4 OS=Homo sapiens GN=ANO4 PE=2 SV=1 75 4e-013
sp|Q8C5H1|ANO4_MOUSE Anoctamin-4 OS=Mus musculus GN=Ano4 PE=2 SV=2 75 4e-013
sp|A1A5B4|ANO9_HUMAN Anoctamin-9 OS=Homo sapiens GN=ANO9 PE=2 SV=2 71 7e-012
sp|P86044|ANO9_MOUSE Anoctamin-9 OS=Mus musculus GN=Ano9 PE=2 SV=1 71 7e-012
sp|Q75V66|ANO5_HUMAN Anoctamin-5 OS=Homo sapiens GN=ANO5 PE=1 SV=1 69 4e-011
sp|Q6IWH7|ANO7_HUMAN Anoctamin-7 OS=Homo sapiens GN=ANO7 PE=1 SV=1 68 8e-011
sp|Q75UR0|ANO5_MOUSE Anoctamin-5 OS=Mus musculus GN=Ano5 PE=2 SV=1 67 1e-010
sp|Q5XXA6|ANO1_HUMAN Anoctamin-1 OS=Homo sapiens GN=ANO1 PE=1 SV=1 66 3e-010
sp|Q8BHY3|ANO1_MOUSE Anoctamin-1 OS=Mus musculus GN=Ano1 PE=1 SV=2 66 3e-010
sp|Q14AT5|ANO7_MOUSE Anoctamin-7 OS=Mus musculus GN=Ano7 PE=2 SV=2 65 5e-010
sp|Q6IFT6|ANO7_RAT Anoctamin-7 OS=Rattus norvegicus GN=Ano7 PE=2... 65 5e-010
>sp|Q8BH79|ANO10_MOUSE Anoctamin-10 OS=Mus musculus GN=Ano10 PE=2 SV=1
Length = 659
Score = 86 bits (212), Expect = 2e-016
Identities = 46/132 (34%), Positives = 77/132 (58%), Gaps = 8/132 (6%)
Frame = +3
Query: 147 GLFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAATI 326
G FDD+LEL LQFG + +F+C +PLA A ++N E+ ++ALK+ +RP +A+I
Sbjct: 493 GTFDDYLELFLQFGYVSLFSCVYPLAAAFAVLNNFTEVNSDALKMCRVFKRPFAEPSASI 552
Query: 327 GAWLNIWQFLVVMSICTNSALL-----VCLYDQEGKWKIEPGLAAILIMEHILLLFKFGL 491
G W ++ + V+S+ TN AL+ V E K + + ++ +EH LL KF L
Sbjct: 553 GVWQLAFETMSVISVVTNCALIGMSPQVNAVFPESKTDL---VLIVVAVEHALLALKFIL 609
Query: 492 SRLVPEEPAWVR 527
+ +P++P ++
Sbjct: 610 AFAIPDKPRHIQ 621
>sp|Q6PB70|ANO8_MOUSE Anoctamin-8 OS=Mus musculus GN=Ano8 PE=2 SV=3
Length = 1060
Score = 86 bits (212), Expect = 2e-016
Identities = 50/165 (30%), Positives = 90/165 (54%), Gaps = 4/165 (2%)
Frame = +3
Query: 153 FDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAATIGA 332
F D+ E+ +QFG +++F+ AFPLA A V+N++E+R++A KL L+RP R +IG
Sbjct: 740 FQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGRRVESIGQ 799
Query: 333 WLNIWQFLVVMSICTNSALL-VCLYDQE-GKW-KIEPGLAAILIMEHILLLFKFGLSRLV 503
W + + + V++I N L+ C Q W E + +++++EH+ LL K+ + +
Sbjct: 800 WQKVMEAMGVLAIVVNCYLIGQCGQLQRLFPWLSPEAAIVSVVVLEHLALLVKYLIHVAI 859
Query: 504 PEEPAWVRANRMKNVTQAQDMYCKQLLRSISGEFSSMAKTQQDSE 638
P+ P WV K Q ++ + K+ R F + +++ E
Sbjct: 860 PDIPGWVAEEMAKLEYQRREAF-KRHERQAQQRFQQQQRRRREEE 903
>sp|Q9NW15|ANO10_HUMAN Anoctamin-10 OS=Homo sapiens GN=ANO10 PE=2 SV=2
Length = 660
Score = 86 bits (211), Expect = 3e-016
Identities = 46/132 (34%), Positives = 76/132 (57%), Gaps = 8/132 (6%)
Frame = +3
Query: 147 GLFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAATI 326
G FDD+LEL LQFG + +F+C +PLA A ++N E+ ++ALK+ +RP +A I
Sbjct: 493 GTFDDYLELFLQFGYVSLFSCVYPLAAAFAVLNNFTEVNSDALKMCRVFKRPFSEPSANI 552
Query: 327 GAWLNIWQFLVVMSICTNSALL-----VCLYDQEGKWKIEPGLAAILIMEHILLLFKFGL 491
G W ++ + V+S+ TN AL+ V E K + + ++ +EH LL KF L
Sbjct: 553 GVWQLAFETMSVISVVTNCALIGMSPQVNAVFPESKADL---ILIVVAVEHALLALKFIL 609
Query: 492 SRLVPEEPAWVR 527
+ +P++P ++
Sbjct: 610 AFAIPDKPRHIQ 621
>sp|Q9HCE9|ANO8_HUMAN Anoctamin-8 OS=Homo sapiens GN=ANO8 PE=2 SV=3
Length = 1232
Score = 83 bits (204), Expect = 2e-015
Identities = 48/165 (29%), Positives = 89/165 (53%), Gaps = 4/165 (2%)
Frame = +3
Query: 153 FDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAATIGA 332
F D+ E+ +QFG +++F+ AFPLA A V+N++E+R++A KL L+RP + +IG
Sbjct: 745 FQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQ 804
Query: 333 WLNIWQFLVVMSICTNSALL-VCLYDQE-GKW-KIEPGLAAILIMEHILLLFKFGLSRLV 503
W + + + V++I N L+ C Q W E + +++++EH LL K+ + +
Sbjct: 805 WQKVMEAMGVLAIVVNCYLIGQCGQLQRLFPWLSPEAAIVSVVVLEHFALLLKYLIHVAI 864
Query: 504 PEEPAWVRANRMKNVTQAQDMYCKQLLRSISGEFSSMAKTQQDSE 638
P+ P WV K Q ++ + K+ R + + +++ E
Sbjct: 865 PDIPGWVAEEMAKLEYQRREAF-KRHERQAQHRYQQQQRRRREEE 908
>sp|Q9BYT9|ANO3_HUMAN Anoctamin-3 OS=Homo sapiens GN=ANO3 PE=2 SV=2
Length = 981
Score = 78 bits (190), Expect = 8e-014
Identities = 36/87 (41%), Positives = 56/87 (64%)
Frame = +3
Query: 147 GLFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAATI 326
GL D++LE+ LQFG +F AFPLA LA ++N++E+R +A K + RRPLP A I
Sbjct: 750 GLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDI 809
Query: 327 GAWLNIWQFLVVMSICTNSALLVCLYD 407
G WL I + + ++++ TN+ ++ D
Sbjct: 810 GIWLGILEGIGILAVITNAFVIAITSD 836
>sp|A2AHL1|ANO3_MOUSE Anoctamin-3 OS=Mus musculus GN=Ano3 PE=2 SV=1
Length = 981
Score = 78 bits (190), Expect = 8e-014
Identities = 36/87 (41%), Positives = 56/87 (64%)
Frame = +3
Query: 147 GLFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAATI 326
GL D++LE+ LQFG +F AFPLA LA ++N++E+R +A K + RRPLP A I
Sbjct: 750 GLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDI 809
Query: 327 GAWLNIWQFLVVMSICTNSALLVCLYD 407
G WL I + + ++++ TN+ ++ D
Sbjct: 810 GIWLGILEGIGILAVITNAFVIAITSD 836
>sp|Q6P9J9|ANO6_MOUSE Anoctamin-6 OS=Mus musculus GN=Ano6 PE=1 SV=1
Length = 911
Score = 77 bits (187), Expect = 2e-013
Identities = 35/87 (40%), Positives = 56/87 (64%)
Frame = +3
Query: 147 GLFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAATI 326
GLF ++LE+ +QFG + +F +FPLA LA V+N++E+R +A KL RR +P A I
Sbjct: 663 GLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRMVPEKAQDI 722
Query: 327 GAWLNIWQFLVVMSICTNSALLVCLYD 407
GAW I Q + ++++ TN+ ++ D
Sbjct: 723 GAWQPIMQGIAILAVVTNAMIIAFTSD 749
>sp|Q4KMQ2|ANO6_HUMAN Anoctamin-6 OS=Homo sapiens GN=ANO6 PE=1 SV=2
Length = 910
Score = 76 bits (186), Expect = 2e-013
Identities = 35/87 (40%), Positives = 56/87 (64%)
Frame = +3
Query: 147 GLFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAATI 326
GLF ++LE+ +QFG + +F +FPLA LA V+N++E+R +A KL RR +P A I
Sbjct: 662 GLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDI 721
Query: 327 GAWLNIWQFLVVMSICTNSALLVCLYD 407
GAW I Q + ++++ TN+ ++ D
Sbjct: 722 GAWQPIMQGIAILAVVTNAMIIAFTSD 748
>sp|A6QLE6|ANO4_BOVIN Anoctamin-4 OS=Bos taurus GN=ANO4 PE=2 SV=1
Length = 920
Score = 75 bits (184), Expect = 4e-013
Identities = 36/87 (41%), Positives = 55/87 (63%)
Frame = +3
Query: 147 GLFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAATI 326
GLFD++LE+ LQFG +F AFPLA LA ++N++E+R +A K + RRPL A I
Sbjct: 673 GLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDI 732
Query: 327 GAWLNIWQFLVVMSICTNSALLVCLYD 407
G W I + + ++S+ TN+ ++ D
Sbjct: 733 GIWYGILEGIGILSVITNAFVIAITSD 759
>sp|Q32M45|ANO4_HUMAN Anoctamin-4 OS=Homo sapiens GN=ANO4 PE=2 SV=1
Length = 955
Score = 75 bits (184), Expect = 4e-013
Identities = 36/87 (41%), Positives = 55/87 (63%)
Frame = +3
Query: 147 GLFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAATI 326
GLFD++LE+ LQFG +F AFPLA LA ++N++E+R +A K + RRPL A I
Sbjct: 708 GLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDI 767
Query: 327 GAWLNIWQFLVVMSICTNSALLVCLYD 407
G W I + + ++S+ TN+ ++ D
Sbjct: 768 GIWYGILEGIGILSVITNAFVIAITSD 794
>sp|Q8C5H1|ANO4_MOUSE Anoctamin-4 OS=Mus musculus GN=Ano4 PE=2 SV=2
Length = 955
Score = 75 bits (184), Expect = 4e-013
Identities = 36/87 (41%), Positives = 55/87 (63%)
Frame = +3
Query: 147 GLFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAATI 326
GLFD++LE+ LQFG +F AFPLA LA ++N++E+R +A K + RRPL A I
Sbjct: 708 GLFDEYLEMILQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLASRAKDI 767
Query: 327 GAWLNIWQFLVVMSICTNSALLVCLYD 407
G W I + + ++S+ TN+ ++ D
Sbjct: 768 GIWYGILEGIGILSVITNAFVIAITSD 794
>sp|A1A5B4|ANO9_HUMAN Anoctamin-9 OS=Homo sapiens GN=ANO9 PE=2 SV=2
Length = 782
Score = 71 bits (173), Expect = 7e-012
Identities = 32/81 (39%), Positives = 54/81 (66%)
Frame = +3
Query: 150 LFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAATIG 329
LFD+F+E+ +Q+G +F AFPLA LA SN++E+R +A+K++ RR +PR A IG
Sbjct: 537 LFDEFMEMMIQYGFTTIFVAAFPLAPLLALFSNLVEIRLDAIKMVWLQRRLVPRKAKDIG 596
Query: 330 AWLNIWQFLVVMSICTNSALL 392
WL + + + V+++ N ++
Sbjct: 597 TWLQVLETIGVLAVIANGMVI 617
>sp|P86044|ANO9_MOUSE Anoctamin-9 OS=Mus musculus GN=Ano9 PE=2 SV=1
Length = 747
Score = 71 bits (173), Expect = 7e-012
Identities = 32/81 (39%), Positives = 54/81 (66%)
Frame = +3
Query: 150 LFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAATIG 329
LFD+F+E+ +Q+G +F AFPLA LA SN++E+R +A+K++ RR +PR A IG
Sbjct: 528 LFDEFMEMMIQYGFTTIFVAAFPLAPLLALFSNLVEIRLDAIKMVRLQRRLVPRKAKDIG 587
Query: 330 AWLNIWQFLVVMSICTNSALL 392
WL + + + V+++ N ++
Sbjct: 588 TWLQVLETIGVLAVIANGMVI 608
>sp|Q75V66|ANO5_HUMAN Anoctamin-5 OS=Homo sapiens GN=ANO5 PE=1 SV=1
Length = 913
Score = 69 bits (167), Expect = 4e-011
Identities = 33/87 (37%), Positives = 53/87 (60%)
Frame = +3
Query: 147 GLFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAATI 326
GLF ++LE QFG + +F +FPLA LA ++N++E+R +A KL RR + A +I
Sbjct: 668 GLFYEYLETVTQFGFVTLFVASFPLAPLLALINNIVEIRVDAWKLTTQYRRTVASKAHSI 727
Query: 327 GAWLNIWQFLVVMSICTNSALLVCLYD 407
G W +I + V+S+ TN+ ++ D
Sbjct: 728 GVWQDILYGMAVLSVATNAFIVAFTSD 754
>sp|Q6IWH7|ANO7_HUMAN Anoctamin-7 OS=Homo sapiens GN=ANO7 PE=1 SV=1
Length = 933
Score = 68 bits (164), Expect = 8e-011
Identities = 33/83 (39%), Positives = 52/83 (62%)
Frame = +3
Query: 144 DGLFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAAT 323
+GLFD++LE+ LQFG + +F A PLA A ++N +E+R +A K + RRP+ A
Sbjct: 702 EGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQD 761
Query: 324 IGAWLNIWQFLVVMSICTNSALL 392
IG W +I L +++ +N+ LL
Sbjct: 762 IGIWFHILAGLTHLAVISNAFLL 784
>sp|Q75UR0|ANO5_MOUSE Anoctamin-5 OS=Mus musculus GN=Ano5 PE=2 SV=1
Length = 904
Score = 67 bits (162), Expect = 1e-010
Identities = 35/101 (34%), Positives = 57/101 (56%)
Frame = +3
Query: 90 EKEYFKPTYSASIGVELEDGLFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTN 269
EK Y + + V GLF ++LE +QFG +F +FPLA A ++N+M +R +
Sbjct: 640 EKLYSRWEQDHDLQVYGHRGLFYEYLETVIQFGFATLFVASFPLAPLFALMNNIMGIRVD 699
Query: 270 ALKLLVTLRRPLPRAAATIGAWLNIWQFLVVMSICTNSALL 392
A KL RRP+ A +IG W +I + ++S+ TN+ ++
Sbjct: 700 AWKLTTQYRRPVAAKAHSIGVWQDILFGMAIVSVATNAFIV 740
>sp|Q5XXA6|ANO1_HUMAN Anoctamin-1 OS=Homo sapiens GN=ANO1 PE=1 SV=1
Length = 986
Score = 66 bits (159), Expect = 3e-010
Identities = 31/96 (32%), Positives = 56/96 (58%)
Frame = +3
Query: 105 KPTYSASIGVELEDGLFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLL 284
K Y +E GL +++E+ +QFG + +F +FPLA A ++N++E+R +A K +
Sbjct: 710 KQRYEVDYNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFV 769
Query: 285 VTLRRPLPRAAATIGAWLNIWQFLVVMSICTNSALL 392
LRRP+ A IG W NI + + +++ N+ ++
Sbjct: 770 TELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVI 805
>sp|Q8BHY3|ANO1_MOUSE Anoctamin-1 OS=Mus musculus GN=Ano1 PE=1 SV=2
Length = 960
Score = 66 bits (159), Expect = 3e-010
Identities = 31/96 (32%), Positives = 56/96 (58%)
Frame = +3
Query: 105 KPTYSASIGVELEDGLFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLL 284
K Y +E GL +++E+ +QFG + +F +FPLA A ++N++E+R +A K +
Sbjct: 684 KQRYEVDFNLEPFAGLTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFV 743
Query: 285 VTLRRPLPRAAATIGAWLNIWQFLVVMSICTNSALL 392
LRRP+ A IG W NI + + +++ N+ ++
Sbjct: 744 TELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVI 779
>sp|Q14AT5|ANO7_MOUSE Anoctamin-7 OS=Mus musculus GN=Ano7 PE=2 SV=2
Length = 859
Score = 65 bits (157), Expect = 5e-010
Identities = 32/83 (38%), Positives = 51/83 (61%)
Frame = +3
Query: 144 DGLFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAAT 323
+GLF ++LE+ LQFG + +F A PLA A ++N +E+R +A K + RRP+ A
Sbjct: 639 EGLFHEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQD 698
Query: 324 IGAWLNIWQFLVVMSICTNSALL 392
IG W +I L +++ +N+ LL
Sbjct: 699 IGIWFHILTGLTHLAVISNAFLL 721
>sp|Q6IFT6|ANO7_RAT Anoctamin-7 OS=Rattus norvegicus GN=Ano7 PE=2 SV=1
Length = 860
Score = 65 bits (157), Expect = 5e-010
Identities = 32/83 (38%), Positives = 51/83 (61%)
Frame = +3
Query: 144 DGLFDDFLELALQFGMIMMFACAFPLAFTLAAVSNVMEMRTNALKLLVTLRRPLPRAAAT 323
+GLF ++LE+ LQFG + +F A PLA A ++N +E+R +A K + RRP+ A
Sbjct: 640 EGLFHEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQD 699
Query: 324 IGAWLNIWQFLVVMSICTNSALL 392
IG W +I L +++ +N+ LL
Sbjct: 700 IGIWFHILAGLTHLAVISNAFLL 722
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 151,686,369,441
Number of Sequences: 518415
Number of Extensions: 151686369441
Number of Successful Extensions: 928182970
Number of sequences better than 0.0: 0
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