BLASTX 7.6.2
Query= UN38882 /QuerySize=2058
(2057 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q6TDP4|KLH17_HUMAN Kelch-like protein 17 OS=Homo sapiens GN=K... 74 3e-012
sp|Q6TDP3|KLH17_MOUSE Kelch-like protein 17 OS=Mus musculus GN=K... 73 8e-012
sp|Q8K430|KLH17_RAT Kelch-like protein 17 OS=Rattus norvegicus G... 73 8e-012
sp|Q9D5V2|KLH10_MOUSE Kelch-like protein 10 OS=Mus musculus GN=K... 59 1e-007
sp|Q6JEL3|KLH10_RAT Kelch-like protein 10 OS=Rattus norvegicus G... 59 1e-007
sp|Q6JEL2|KLH10_HUMAN Kelch-like protein 10 OS=Homo sapiens GN=K... 58 2e-007
sp|Q8WZ60|KLHL6_HUMAN Kelch-like protein 6 OS=Homo sapiens GN=KL... 56 8e-007
>sp|Q6TDP4|KLH17_HUMAN Kelch-like protein 17 OS=Homo sapiens GN=KLHL17 PE=2
SV=1
Length = 642
Score = 74 bits (181), Expect = 3e-012
Identities = 69/242 (28%), Positives = 113/242 (46%), Gaps = 17/242 (7%)
Frame = +2
Query: 512 GMDCSKVVRVI--ELHISSPILAAKSPFFYKLFSNGMRESEQRHVTLRINASEEAALMEL 685
G+ C V+ V E+ +LA+ SP+F+ +F+N M ES Q HVTL + + AL +L
Sbjct: 89 GLLCDIVLHVAAKEIRAHKVVLASCSPYFHAMFTNEMSESRQTHVTL--HDIDPQALDQL 146
Query: 686 LNFMYSNVVSVATAPALLDVLMAADKFEVASCMRYCSRLLRNMPMTPESALLYLELPSSV 865
+ F Y+ + V + +L AA ++ C + L + + P + L
Sbjct: 147 VQFAYTAEIVVGEG-NVQTLLPAASLLQLNGVRDACCKFLLSQ-LDPSNCLGIRGFAD-- 202
Query: 866 LMAKAVQPLTDAAKQFLAARYKDITKFQEEVMSLPLAGIEAILSSDDLQIASEDAVYDFI 1045
A + L AA +++ + D+ K EE M LPL + ++SSD L + SE+ VY +
Sbjct: 203 --AHSCSDLLKAAHRYVLQHFVDVAK-TEEFMLLPLKQVLELVSSDSLNVPSEEEVYRAV 259
Query: 1046 LKWARAQYPVLEERREVLGSRLALSIRFPFMTCRKLKKVLTCSDF--DHEIASKLVLEAL 1219
L W + + V R+ V RL +R P ++ L + H L++EAL
Sbjct: 260 LSWVK--HDVDARRQHV--PRLMKCVRLPLLSRDFLLGHVDAESLVRHHPDCKDLLIEAL 315
Query: 1220 FF 1225
F
Sbjct: 316 KF 317
>sp|Q6TDP3|KLH17_MOUSE Kelch-like protein 17 OS=Mus musculus GN=Klhl17 PE=2
SV=1
Length = 640
Score = 73 bits (177), Expect = 8e-012
Identities = 68/242 (28%), Positives = 113/242 (46%), Gaps = 17/242 (7%)
Frame = +2
Query: 512 GMDCSKVVRVI--ELHISSPILAAKSPFFYKLFSNGMRESEQRHVTLRINASEEAALMEL 685
G+ C V+ V E+ +LA+ SP+F+ +F+N M ES Q HVTL + + AL +L
Sbjct: 87 GLLCDIVLHVAAKEIRAHKVVLASCSPYFHAMFTNEMSESRQTHVTL--HDIDPQALDQL 144
Query: 686 LNFMYSNVVSVATAPALLDVLMAADKFEVASCMRYCSRLLRNMPMTPESALLYLELPSSV 865
+ F Y+ + V + +L AA ++ C + L + + P + L +
Sbjct: 145 VQFAYTAEIVVGEG-NVQTLLPAASLLQLNGVRDACCKFLLSQ-LDPSNCLGIRGFADT- 201
Query: 866 LMAKAVQPLTDAAKQFLAARYKDITKFQEEVMSLPLAGIEAILSSDDLQIASEDAVYDFI 1045
+ L AA +++ + D+ K EE M LPL + ++SSD L + SE+ VY +
Sbjct: 202 ---HSCSDLLKAAHRYVLQHFVDVAK-TEEFMLLPLKQVLELVSSDSLNVPSEEDVYRAV 257
Query: 1046 LKWARAQYPVLEERREVLGSRLALSIRFPFMTCRKLKKVLTCSDF--DHEIASKLVLEAL 1219
L W + + V R+ V RL +R P ++ L + H L++EAL
Sbjct: 258 LSWVK--HDVDTRRQHV--PRLMKCVRLPLLSRDFLLGHVDAESLVRHHPDCKDLLIEAL 313
Query: 1220 FF 1225
F
Sbjct: 314 KF 315
>sp|Q8K430|KLH17_RAT Kelch-like protein 17 OS=Rattus norvegicus GN=Klhl17 PE=1
SV=1
Length = 640
Score = 73 bits (177), Expect = 8e-012
Identities = 68/242 (28%), Positives = 113/242 (46%), Gaps = 17/242 (7%)
Frame = +2
Query: 512 GMDCSKVVRVI--ELHISSPILAAKSPFFYKLFSNGMRESEQRHVTLRINASEEAALMEL 685
G+ C V+ V E+ +LA+ SP+F+ +F+N M ES Q HVTL + + AL +L
Sbjct: 87 GLLCDIVLHVAAKEIRAHKVVLASCSPYFHAMFTNEMSESRQTHVTL--HDIDPQALDQL 144
Query: 686 LNFMYSNVVSVATAPALLDVLMAADKFEVASCMRYCSRLLRNMPMTPESALLYLELPSSV 865
+ F Y+ + V + +L AA ++ C + L + + P + L +
Sbjct: 145 VQFAYTAEIVVGEG-NVQTLLPAASLLQLNGVRDACCKFLLSQ-LDPSNCLGIRGFADT- 201
Query: 866 LMAKAVQPLTDAAKQFLAARYKDITKFQEEVMSLPLAGIEAILSSDDLQIASEDAVYDFI 1045
+ L AA +++ + D+ K EE M LPL + ++SSD L + SE+ VY +
Sbjct: 202 ---HSCSDLLKAAHRYVLQHFVDVAK-TEEFMLLPLKQVLELVSSDSLNVPSEEDVYRAV 257
Query: 1046 LKWARAQYPVLEERREVLGSRLALSIRFPFMTCRKLKKVLTCSDF--DHEIASKLVLEAL 1219
L W + + V R+ V RL +R P ++ L + H L++EAL
Sbjct: 258 LSWVK--HDVDTRRQHV--PRLMKCVRLPLLSRDFLLGHVDAESLVRHHPDCKDLLIEAL 313
Query: 1220 FF 1225
F
Sbjct: 314 KF 315
>sp|Q9D5V2|KLH10_MOUSE Kelch-like protein 10 OS=Mus musculus GN=Klhl10 PE=2
SV=1
Length = 608
Score = 59 bits (141), Expect = 1e-007
Identities = 45/188 (23%), Positives = 85/188 (45%), Gaps = 20/188 (10%)
Frame = +2
Query: 512 GMDCSKVVRV--IELHISSPILAAKSPFFYKLFSNGMRESEQRHVTLRINASEEAALMEL 685
G C V++V E + IL + S +F LF++G +E++ I + +
Sbjct: 36 GKLCDVVIKVNGFEFNAHKNILCSCSSYFRALFTSGWNNTEKK--VYNIPGISPDMMKLI 93
Query: 686 LNFMYSNVVSVATAPALLDVLMAADKFEVASCMRYCSRLLRNMPMTPESALLYLELPSSV 865
+ + Y+ V + T + +L AAD+F + +R C L++ L L + +
Sbjct: 94 IEYAYTRTVPI-TPDNVEKLLAAADQFNIMGIVRGCCEFLKS----------ELCLDNCI 142
Query: 866 LMAKAVQ-----PLTDAAKQFLAARYKDITKFQEEVMSLPLAGIEAILSSDDLQIASEDA 1030
+ K L A F+ ++++ K E + L + ++ I+ D+L + EDA
Sbjct: 143 GICKFTDYYYCPELRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDA 202
Query: 1031 VYDFILKW 1054
V++ ILKW
Sbjct: 203 VFEAILKW 210
>sp|Q6JEL3|KLH10_RAT Kelch-like protein 10 OS=Rattus norvegicus GN=Klhl10 PE=2
SV=1
Length = 608
Score = 59 bits (141), Expect = 1e-007
Identities = 45/188 (23%), Positives = 85/188 (45%), Gaps = 20/188 (10%)
Frame = +2
Query: 512 GMDCSKVVRV--IELHISSPILAAKSPFFYKLFSNGMRESEQRHVTLRINASEEAALMEL 685
G C V++V E + IL + S +F LF++G +E++ I + +
Sbjct: 36 GKLCDVVIKVNGFEFNAHKNILCSCSSYFRALFTSGWNNTEKK--VYNIPGISPDMMKLI 93
Query: 686 LNFMYSNVVSVATAPALLDVLMAADKFEVASCMRYCSRLLRNMPMTPESALLYLELPSSV 865
+ + Y+ V + T + +L AAD+F + +R C L++ L L + +
Sbjct: 94 IEYAYTRTVPI-TPDNVEKLLAAADQFNIMGIVRGCCEFLKS----------ELCLDNCI 142
Query: 866 LMAKAVQ-----PLTDAAKQFLAARYKDITKFQEEVMSLPLAGIEAILSSDDLQIASEDA 1030
+ K L A F+ ++++ K E + L + ++ I+ D+L + EDA
Sbjct: 143 GICKFTDYYYCPELRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDA 202
Query: 1031 VYDFILKW 1054
V++ ILKW
Sbjct: 203 VFEAILKW 210
>sp|Q6JEL2|KLH10_HUMAN Kelch-like protein 10 OS=Homo sapiens GN=KLHL10 PE=2
SV=1
Length = 608
Score = 58 bits (139), Expect = 2e-007
Identities = 45/188 (23%), Positives = 84/188 (44%), Gaps = 20/188 (10%)
Frame = +2
Query: 512 GMDCSKVVRV--IELHISSPILAAKSPFFYKLFSNGMRESEQRHVTLRINASEEAALMEL 685
G C V++V E IL + S +F LF++G +E++ I + +
Sbjct: 36 GKLCDVVIKVNGFEFSAHKNILCSCSSYFRALFTSGWNNTEKK--VYNIPGISPDMMKLI 93
Query: 686 LNFMYSNVVSVATAPALLDVLMAADKFEVASCMRYCSRLLRNMPMTPESALLYLELPSSV 865
+ + Y+ V + T + +L AAD+F + +R C L++ L L + +
Sbjct: 94 IEYAYTRTVPI-TPDNVEKLLAAADQFNIMGIVRGCCEFLKS----------ELCLDNCI 142
Query: 866 LMAKAVQ-----PLTDAAKQFLAARYKDITKFQEEVMSLPLAGIEAILSSDDLQIASEDA 1030
+ K L A F+ ++++ K E + L + ++ I+ D+L + EDA
Sbjct: 143 GICKFTDYYYCPELRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDA 202
Query: 1031 VYDFILKW 1054
V++ ILKW
Sbjct: 203 VFEAILKW 210
>sp|Q8WZ60|KLHL6_HUMAN Kelch-like protein 6 OS=Homo sapiens GN=KLHL6 PE=2 SV=3
Length = 621
Score = 56 bits (134), Expect = 8e-007
Identities = 42/176 (23%), Positives = 82/176 (46%), Gaps = 9/176 (5%)
Frame = +2
Query: 533 VRVIELHISSPILAAKSPFFYKLFSNGMRESEQRHVTLRINASEEAALMELLNFMYSNVV 712
V + E +LAA S +F +F N ++E ++ + I + + LL++ Y++
Sbjct: 78 VDIQEFSCHRVVLAAASNYFRAMFCNDLKEKYEKRII--IKGVDAETMHTLLDYTYTS-K 134
Query: 713 SVATAPALLDVLMAADKFEVASCMRYCSRLLRNMPMTPESALLYLELPSSVLMAKAVQPL 892
++ T + VL AA+ F+ + C+ L + PE+ + L L + ++ L
Sbjct: 135 ALITKQNVQRVLEAANLFQFLRMVDACASFLTE-ALNPENCVGILRLADT----HSLDSL 189
Query: 893 TDAAKQFLAARYKDITKFQEEVMSLPLAGIEAILSSDDLQIASEDAVYDFILKWAR 1060
+ ++ + I EE + LP+ + IL SDDL + E V++ ++ W R
Sbjct: 190 KKQVQSYIIQNFVQILN-SEEFLDLPVDTLHHILKSDDLYVTEEAQVFETVMSWVR 244
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 151,686,369,441
Number of Sequences: 518415
Number of Extensions: 151686369441
Number of Successful Extensions: 928182970
Number of sequences better than 0.0: 0
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