BLASTX 7.6.2
Query= UN39578 /QuerySize=741
(740 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q13268|DHRS2_HUMAN Dehydrogenase/reductase SDR family member ... 181 7e-045
sp|Q9BTZ2|DHRS4_HUMAN Dehydrogenase/reductase SDR family member ... 179 3e-044
sp|Q5RCF8|DHRS4_PONAB Dehydrogenase/reductase SDR family member ... 178 4e-044
sp|Q8WNV7|DHRS4_PIG Dehydrogenase/reductase SDR family member 4 ... 171 5e-042
sp|Q8SPU8|DHRS4_BOVIN Dehydrogenase/reductase SDR family member ... 170 9e-042
sp|Q99LB2|DHRS4_MOUSE Dehydrogenase/reductase SDR family member ... 170 9e-042
sp|Q8VID1|DHRS4_RAT Dehydrogenase/reductase SDR family member 4 ... 169 2e-041
sp|Q9GKX2|DHRS4_RABIT Dehydrogenase/reductase SDR family member ... 168 5e-041
sp|Q6PKH6|DR4L2_HUMAN Dehydrogenase/reductase SDR family member ... 154 5e-037
sp|P0CG22|DR4L1_HUMAN Putative dehydrogenase/reductase SDR famil... 142 4e-033
sp|P50164|TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamus niger G... 97 1e-019
sp|P47230|BPHB_RHOGO Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogen... 97 1e-019
sp|P50163|TRN2_DATST Tropinone reductase 2 OS=Datura stramonium ... 94 1e-018
sp|P0AET9|HDHA_ECO57 7-alpha-hydroxysteroid dehydrogenase OS=Esc... 93 1e-018
sp|P0AET8|HDHA_ECOLI 7-alpha-hydroxysteroid dehydrogenase OS=Esc... 93 1e-018
sp|P08694|BPHB_PSEPS Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogen... 91 5e-018
sp|P80873|GS39_BACSU General stress protein 39 OS=Bacillus subti... 89 2e-017
sp|Q5HJP2|BUTA_STAAC Acetoin(diacetyl) reductase OS=Staphylococc... 89 4e-017
sp|P66775|BUTA_STAAM Acetoin(diacetyl) reductase OS=Staphylococc... 89 4e-017
sp|P99120|BUTA_STAAN Acetoin(diacetyl) reductase OS=Staphylococc... 89 4e-017
>sp|Q13268|DHRS2_HUMAN Dehydrogenase/reductase SDR family member 2 OS=Homo
sapiens GN=DHRS2 PE=1 SV=3
Length = 258
Score = 181 bits (457), Expect = 7e-045
Identities = 92/205 (44%), Positives = 130/205 (63%), Gaps = 2/205 (0%)
Frame = +2
Query: 119 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 298
L +VA+VT ST GIGF I R +GA VV+SSRKQ NV+ A+ KL+ +G+ GIVCH
Sbjct: 12 LANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCH 71
Query: 299 VSNAQHRRDLVEKTVQKYGKIDIVVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 478
V A+ R LV K ++ G +D +VC+A NP L T E + DK+ +NVKS LLL
Sbjct: 72 VGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLL 131
Query: 479 QDMAPHLE-KGSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNAV 652
+ P++E + +VI ++SIA + P ++ +Y V+KTALLGLT+ LA E+ P D RVN V
Sbjct: 132 SQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCV 191
Query: 653 APGFVPTHFASFITGNSQVRESIEE 727
PG + T F+ GN + ++ +E
Sbjct: 192 VPGIIKTDFSKVFHGNESLWKNFKE 216
>sp|Q9BTZ2|DHRS4_HUMAN Dehydrogenase/reductase SDR family member 4 OS=Homo
sapiens GN=DHRS4 PE=1 SV=2
Length = 260
Score = 179 bits (452), Expect = 3e-044
Identities = 98/206 (47%), Positives = 131/206 (63%), Gaps = 3/206 (1%)
Frame = +2
Query: 119 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 298
L KVA+VTAST GIGF I R +GA VVVSSRKQ NV++AV L+ +G+ G VCH
Sbjct: 12 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 71
Query: 299 VSNAQHRRDLVEKTVQKYGKIDIVVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 478
V A+ R LV V+ +G IDI+V NAA NP I+ E V DK +INVK+ L+
Sbjct: 72 VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMT 131
Query: 479 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 649
+ + P +EK G SV+ ++SIA F P + Y V+KTALLGLTK LA E+ P + RVN
Sbjct: 132 KAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNC 191
Query: 650 VAPGFVPTHFASFITGNSQVRESIEE 727
+APG + T F+ + + + ES++E
Sbjct: 192 LAPGLIKTSFSRMLWMDKEKEESMKE 217
>sp|Q5RCF8|DHRS4_PONAB Dehydrogenase/reductase SDR family member 4 OS=Pongo
abelii GN=DHRS4 PE=2 SV=2
Length = 260
Score = 178 bits (450), Expect = 4e-044
Identities = 97/206 (47%), Positives = 131/206 (63%), Gaps = 3/206 (1%)
Frame = +2
Query: 119 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 298
L KVA+VTAST GIGF I R +GA VVVSSRKQ NV++AV L+ +G+ G VCH
Sbjct: 12 LANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 71
Query: 299 VSNAQHRRDLVEKTVQKYGKIDIVVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 478
V A+ R LV V+ +G IDI+V NAA NP ++ E V DK +INVK+ L+
Sbjct: 72 VGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMT 131
Query: 479 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 649
+ + P +EK G SV+ ++SIA F P + Y V+KTALLGLTK LA E+ P + RVN
Sbjct: 132 KAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNC 191
Query: 650 VAPGFVPTHFASFITGNSQVRESIEE 727
+APG + T F+ + + + ES++E
Sbjct: 192 LAPGLIKTSFSRMLWMDKEKEESMKE 217
>sp|Q8WNV7|DHRS4_PIG Dehydrogenase/reductase SDR family member 4 OS=Sus scrofa
GN=DHRS4 PE=1 SV=1
Length = 260
Score = 171 bits (432), Expect = 5e-042
Identities = 91/206 (44%), Positives = 130/206 (63%), Gaps = 3/206 (1%)
Frame = +2
Query: 119 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 298
LE KVA+VTAST GIG I R +GA VVVSSRKQ NV+ V L+ +G+ G VCH
Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCH 71
Query: 299 VSNAQHRRDLVEKTVQKYGKIDIVVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 478
V A+ R LV V +G +DI+V NAA NP I+ E V DK+ +NVK+++L+
Sbjct: 72 VGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMT 131
Query: 479 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 649
+ + P +EK G SV+ ++S+ + P ++ Y V+KTALLGLTK LA E+ P + RVN
Sbjct: 132 KAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNC 191
Query: 650 VAPGFVPTHFASFITGNSQVRESIEE 727
+APG + T+F+ + + +E ++E
Sbjct: 192 LAPGLIKTNFSQVLWMDKARKEYMKE 217
>sp|Q8SPU8|DHRS4_BOVIN Dehydrogenase/reductase SDR family member 4 OS=Bos taurus
GN=DHRS4 PE=2 SV=1
Length = 260
Score = 170 bits (430), Expect = 9e-042
Identities = 92/205 (44%), Positives = 131/205 (63%), Gaps = 3/205 (1%)
Frame = +2
Query: 119 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 298
L+ KVA+VTAST GIGF I R +GA VVVSSRKQ NV+ AV LK +G+ G VCH
Sbjct: 12 LDNKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDRAVATLKGEGLSVTGTVCH 71
Query: 299 VSNAQHRRDLVEKTVQKYGKIDIVVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 478
V A+ R LV V+ +G +DI++ NAA +P ++ E V DK+ ++NVK++ LL
Sbjct: 72 VGKAEDRERLVATAVKLHGGVDILISNAAVSPFFGSLMDVPEEVWDKILDVNVKATALLT 131
Query: 479 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMG-PDTRVNA 649
+ + P + K G S++ ++SIA + P S+ Y V+KTALLGLTK LA E+ + RVN
Sbjct: 132 KAVVPEMAKRGGGSIVIVSSIAAYSPFPSLGPYNVSKTALLGLTKNLALELAESNVRVNC 191
Query: 650 VAPGFVPTHFASFITGNSQVRESIE 724
+APG + T F+ + + +ESI+
Sbjct: 192 LAPGLIRTSFSRVLWEDPARQESIK 216
>sp|Q99LB2|DHRS4_MOUSE Dehydrogenase/reductase SDR family member 4 OS=Mus
musculus GN=Dhrs4 PE=2 SV=1
Length = 260
Score = 170 bits (430), Expect = 9e-042
Identities = 93/206 (45%), Positives = 130/206 (63%), Gaps = 3/206 (1%)
Frame = +2
Query: 119 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 298
L KVA+VTAST GIGF I R +GA VVVSSRKQ NV+ AV L+ +G+ GIVCH
Sbjct: 12 LSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATLQGEGLSVTGIVCH 71
Query: 299 VSNAQHRRDLVEKTVQKYGKIDIVVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 478
V A+ R L+ ++++ IDI+V NAA NP ++ E V DK+ INV ++ +++
Sbjct: 72 VGKAEDREKLITTALKRHRGIDILVSNAAVNPFFGNLMDVTEEVWDKVLSINVTATAMMI 131
Query: 479 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 649
+ + P +EK G SV+ + S+AGF S+ Y V+KTALLGLTK AAE+ P + RVN
Sbjct: 132 KAVVPEMEKRGGGSVVIVGSVAGFTRFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNC 191
Query: 650 VAPGFVPTHFASFITGNSQVRESIEE 727
+APG + T F+S + + I+E
Sbjct: 192 LAPGLIKTRFSSVLWEEKAREDFIKE 217
>sp|Q8VID1|DHRS4_RAT Dehydrogenase/reductase SDR family member 4 OS=Rattus
norvegicus GN=Dhrs4 PE=2 SV=1
Length = 260
Score = 169 bits (428), Expect = 2e-041
Identities = 93/206 (45%), Positives = 130/206 (63%), Gaps = 3/206 (1%)
Frame = +2
Query: 119 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 298
L KVA+VTAST GIG I R +GA VV+SSRKQ NV+ AV L+ +G+ G+VCH
Sbjct: 12 LANKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATLQGEGLSVTGVVCH 71
Query: 299 VSNAQHRRDLVEKTVQKYGKIDIVVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 478
V A+ R LV ++ + IDI+V NAA NP ++ E V +K+ INV +S +++
Sbjct: 72 VGKAEDREKLVNMALKLHQGIDILVSNAAVNPFFGNLMDVTEEVWNKVLSINVTASAMMI 131
Query: 479 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 649
+ + P +EK G SV+ ++S+AGF S+ Y V+KTALLGLTK AAE+ P + RVN
Sbjct: 132 KAVVPAMEKRGGGSVVIVSSVAGFVLFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNC 191
Query: 650 VAPGFVPTHFASFITGNSQVRESIEE 727
+APG + THF+S + E I+E
Sbjct: 192 LAPGLIKTHFSSVLWKEKAREEMIKE 217
>sp|Q9GKX2|DHRS4_RABIT Dehydrogenase/reductase SDR family member 4
OS=Oryctolagus cuniculus GN=DHRS4 PE=1 SV=1
Length = 260
Score = 168 bits (424), Expect = 5e-041
Identities = 93/207 (44%), Positives = 127/207 (61%), Gaps = 3/207 (1%)
Frame = +2
Query: 119 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 298
L KVAIVTAST GIG I R +GA VV+SSRKQ NV+ AV L+++G+ G VCH
Sbjct: 12 LANKVAIVTASTDGIGLAIARRLAQDGAHVVISSRKQQNVDRAVAALQAEGLSVTGTVCH 71
Query: 299 VSNAQHRRDLVEKTVQKYGKIDIVVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 478
V A+ R LV + +G IDI+V NAA NP ++ E V DK+ +INVK+ L+
Sbjct: 72 VGKAEDRERLVATALNLHGGIDILVSNAAVNPFFGKLMDVTEEVWDKILDINVKAMALMT 131
Query: 479 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEM-GPDTRVNA 649
+ + P +EK G SV+ + SIA F P + Y V+KTAL+GLTK LA E+ + RVN
Sbjct: 132 KAVVPEMEKRGGGSVVIVASIAAFNPFSGLGPYNVSKTALVGLTKNLALELAAQNIRVNC 191
Query: 650 VAPGFVPTHFASFITGNSQVRESIEEK 730
+APG + T F+ + + E+I +K
Sbjct: 192 LAPGLIKTSFSKALWEDKAQEENIIQK 218
>sp|Q6PKH6|DR4L2_HUMAN Dehydrogenase/reductase SDR family member 4-like 2
OS=Homo sapiens GN=DHRS4L2 PE=2 SV=1
Length = 230
Score = 154 bits (389), Expect = 5e-037
Identities = 86/181 (47%), Positives = 113/181 (62%), Gaps = 3/181 (1%)
Frame = +2
Query: 119 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 298
L KVA+VTAST GIGF I R + A VVVSSRKQ NV++AV L+ +G+ G VCH
Sbjct: 28 LTNKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCH 87
Query: 299 VSNAQHRRDLVEKTVQKYGKIDIVVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLL 478
V A+ R LV V+ +G IDI+V NAA NP ++ E V DK +INVK+ L+
Sbjct: 88 VGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMT 147
Query: 479 QDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTRVNA 649
+ + P +EK G SV+ ++SIA F P + Y V+KTALLGL LA E+ P + RVN
Sbjct: 148 KAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRVNC 207
Query: 650 V 652
+
Sbjct: 208 L 208
>sp|P0CG22|DR4L1_HUMAN Putative dehydrogenase/reductase SDR family member 4-like
2 OS=Homo sapiens GN=DHRS4L1 PE=5 SV=1
Length = 281
Score = 142 bits (356), Expect = 4e-033
Identities = 83/208 (39%), Positives = 123/208 (59%), Gaps = 6/208 (2%)
Frame = +2
Query: 119 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 298
L KVA+VTAST IGF + +R +GA VVVS RKQ NV++AV L+ +G+ G VCH
Sbjct: 30 LTNKVALVTASTDWIGFAVAQRLAQDGAHVVVSRRKQQNVDQAVATLQGEGLSMTGTVCH 89
Query: 299 VSNAQHRRDLVEKTVQKYGKIDIV---VCNAAANPSTDPILSTKEAVLDKLWEINVKSSI 469
V + LV ++ +G IDI+ + N+ +L T E D+ +IN K+
Sbjct: 90 VGKMKDWERLVATAMKLHGVIDILSLSITNSKRGLFWFTLLQTAEEAWDRNLDINGKALA 149
Query: 470 LLLQDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP-DTR 640
L+++ + P +EK G SV F+ S+A F+P + Y V+KTALLGL K LA E+ P + R
Sbjct: 150 LMIKAVVPEMEKRGGGSVGFLASVAAFRPLPGFSPYNVSKTALLGLNKTLAIELAPRNIR 209
Query: 641 VNAVAPGFVPTHFASFITGNSQVRESIE 724
VN +APG + T F+ + + + ES++
Sbjct: 210 VNCLAPGLIKTSFSRMLWMDKEKEESMK 237
>sp|P50164|TRN2_HYONI Tropinone reductase 2 OS=Hyoscyamus niger GN=TR2 PE=2
SV=1
Length = 260
Score = 97 bits (240), Expect = 1e-019
Identities = 71/214 (33%), Positives = 112/214 (52%), Gaps = 19/214 (8%)
Frame = +2
Query: 119 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 298
LEG A+VT ++GIG+GI+E GASV SR Q ++E + + +SKG + VC
Sbjct: 7 LEGCTALVTGGSRGIGYGIVEELANLGASVYTCSRNQKELDECLTQWRSKGFNVEASVCD 66
Query: 299 VSNAQHRRDLVEKTVQK--YGKIDIVVCNAAANPSTDPILSTKEAV------LDKLWEIN 454
+S+ R + + KTV +GK++I+V NA I+ KEA + IN
Sbjct: 67 LSSRSEREEFM-KTVSNHFHGKLNILVNNAG-------IVIYKEAKDYTMEDYSHIMSIN 118
Query: 455 VKSSILLLQDMAPHLE--KGSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMG 628
+++ L P L+ + +V+FI+SI+G A+YG TK A+ LT+ LA E
Sbjct: 119 FEAAYHLSVLAHPFLKASERGNVVFISSISGASALPYEAVYGATKGAMDQLTRCLAFEWA 178
Query: 629 PDT-RVNAVAPGFVPTHFASFITGNSQVRESIEE 727
D RVN V PG + T + + +E++++
Sbjct: 179 KDNIRVNGVGPGVIATSMVEMTIQDPEQKENLDK 212
>sp|P47230|BPHB_RHOGO Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
OS=Rhodococcus globerulus GN=bphB PE=3 SV=1
Length = 280
Score = 97 bits (239), Expect = 1e-019
Identities = 65/188 (34%), Positives = 97/188 (51%), Gaps = 10/188 (5%)
Frame = +2
Query: 116 RLEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVC 295
RL+ +V +VT G+G I++RF EGA V V R A +EE + G +
Sbjct: 2 RLQDEVVLVTGGCAGLGRAIVDRFVCEGARVAVLDRSVAGLEEL---RAAHGDAVVAVEG 58
Query: 296 HVSNAQHRRDLVEKTVQKYGKIDIVVCNAAANPSTDPILSTKE----AVLDKLWEINVKS 463
V ++ V K V+ +GK+D + NA + ++ E D+++ INVK
Sbjct: 59 DVRYLDSHKETVAKCVETFGKLDCYIGNAGVWDYSTALVEIPEDRLDEAFDEMYSINVKG 118
Query: 464 SILLLQDM--APHLEKGSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGPDT 637
+L ++ A + +G SVIF S AGF P G A+Y K A++G+ K LA E+GP
Sbjct: 119 YLLGVKAALGALYASRG-SVIFTVSNAGFYPAGGGALYTGAKHAIVGMVKQLAYELGPHI 177
Query: 638 RVNAVAPG 661
RVN +APG
Sbjct: 178 RVNGIAPG 185
>sp|P50163|TRN2_DATST Tropinone reductase 2 OS=Datura stramonium GN=TR2 PE=1
SV=1
Length = 260
Score = 94 bits (231), Expect = 1e-018
Identities = 67/213 (31%), Positives = 108/213 (50%), Gaps = 17/213 (7%)
Frame = +2
Query: 119 LEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCH 298
LEG A+VT ++GIG+GI+E GASV SR Q + + + + +SKG VC
Sbjct: 7 LEGCTALVTGGSRGIGYGIVEELASLGASVYTCSRNQKELNDCLTQWRSKGFKVEASVCD 66
Query: 299 VSNAQHRRDLVEKTVQKY-GKIDIVVCNAAANPSTDPILSTKEAV------LDKLWEINV 457
+S+ R++L+ + GK++I+V NA I+ KEA + IN
Sbjct: 67 LSSRSERQELMNTVANHFHGKLNILVNNAG-------IVIYKEAKDYTVEDYSLIMSINF 119
Query: 458 KSSILLLQDMAPHLE--KGSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGP 631
+++ L P L+ + +V+FI+S++G A+YG TK A+ LT+ LA E
Sbjct: 120 EAAYHLSVLAHPFLKASERGNVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAFEWAK 179
Query: 632 DT-RVNAVAPGFVPTHFASFITGNSQVRESIEE 727
D RVN V PG + T + + +E++ +
Sbjct: 180 DNIRVNGVGPGVIATSLVEMTIQDPEQKENLNK 212
>sp|P0AET9|HDHA_ECO57 7-alpha-hydroxysteroid dehydrogenase OS=Escherichia coli
O157:H7 GN=hdhA PE=3 SV=1
Length = 255
Score = 93 bits (230), Expect = 1e-018
Identities = 70/213 (32%), Positives = 105/213 (49%), Gaps = 16/213 (7%)
Frame = +2
Query: 116 RLEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVC 295
RL+GK AI+T + GIG I F GASVVVS V++++ G A+ C
Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67
Query: 296 HVSNAQHRRDLVEKTVQKYGKIDIVVCNAAA---NPSTDPILSTKEAVLDKLWEINVKSS 466
+++ Q L + + K GK+DI+V NA P P+ + A +E+NV S
Sbjct: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRA-----YELNVFSF 122
Query: 467 ILLLQDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMG-PDT 637
L Q +AP +EK G ++ ITS+A +M Y +K A L + +A ++G +
Sbjct: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182
Query: 638 RVNAVAPGFVPTHFASFITGNSQVRESIEEKTL 736
RVN +APG + T S + IE+K L
Sbjct: 183 RVNGIAPGAILTDAL-----KSVITPEIEQKML 210
>sp|P0AET8|HDHA_ECOLI 7-alpha-hydroxysteroid dehydrogenase OS=Escherichia coli
(strain K12) GN=hdhA PE=1 SV=1
Length = 255
Score = 93 bits (230), Expect = 1e-018
Identities = 70/213 (32%), Positives = 105/213 (49%), Gaps = 16/213 (7%)
Frame = +2
Query: 116 RLEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVC 295
RL+GK AI+T + GIG I F GASVVVS V++++ G A+ C
Sbjct: 8 RLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRC 67
Query: 296 HVSNAQHRRDLVEKTVQKYGKIDIVVCNAAA---NPSTDPILSTKEAVLDKLWEINVKSS 466
+++ Q L + + K GK+DI+V NA P P+ + A +E+NV S
Sbjct: 68 DITSEQELSALADFAISKLGKVDILVNNAGGGGPKPFDMPMADFRRA-----YELNVFSF 122
Query: 467 ILLLQDMAPHLEK--GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMG-PDT 637
L Q +AP +EK G ++ ITS+A +M Y +K A L + +A ++G +
Sbjct: 123 FHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLGEKNI 182
Query: 638 RVNAVAPGFVPTHFASFITGNSQVRESIEEKTL 736
RVN +APG + T S + IE+K L
Sbjct: 183 RVNGIAPGAILTDAL-----KSVITPEIEQKML 210
>sp|P08694|BPHB_PSEPS Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
OS=Pseudomonas pseudoalcaligenes GN=bphB PE=3 SV=2
Length = 275
Score = 91 bits (225), Expect = 5e-018
Identities = 55/186 (29%), Positives = 92/186 (49%), Gaps = 8/186 (4%)
Frame = +2
Query: 116 RLEGKVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVC 295
+L+G+ ++T G+G +++RF E V+ + E E G + GIV
Sbjct: 2 KLKGEAVLITGGASGLGRALVDRFVAEAKVAVLDK----SAERLAELETDLGDNVLGIVG 57
Query: 296 HVSNAQHRRDLVEKTVQKYGKIDIVVCNAAANPSTDPILSTKE----AVLDKLWEINVKS 463
V + + ++ + V ++GKID ++ NA + ++ E A D+++ INVK
Sbjct: 58 DVRSLEDQKQAASRCVARFGKIDTLIPNAGIWDYSTALVDLPEESLDAAFDEVFHINVKG 117
Query: 464 SILLLQDMAPHLEKGSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGPDTRV 643
I ++ + + +VIF S AGF P G +Y K A++GL + LA E+ P RV
Sbjct: 118 YIHAVKALPALVASRGNVIFTISNAGFYPNGGGPLYTAAKQAIVGLVRELAFELAPYVRV 177
Query: 644 NAVAPG 661
N V PG
Sbjct: 178 NGVGPG 183
>sp|P80873|GS39_BACSU General stress protein 39 OS=Bacillus subtilis GN=ydaD
PE=1 SV=3
Length = 286
Score = 89 bits (220), Expect = 2e-017
Identities = 59/193 (30%), Positives = 97/193 (50%), Gaps = 2/193 (1%)
Frame = +2
Query: 89 EMEGKKIGRRLEGKVAIVTASTQGIGFGIIERFGLEGASV-VVSSRKQANVEEAVEKLKS 265
E E K +L+GKVA++T GIG + + EGA + +V + + EE ++++
Sbjct: 30 EYEDYKGADKLKGKVALITGGDSGIGRAVSVAYAKEGADIAIVYKDEHEDAEETKKRVEQ 89
Query: 266 KGIDAYGIVCHVSNAQHRRDLVEKTVQKYGKIDIVVCNAAANPSTDPILSTKEAVLDKLW 445
+G+ I V + + VEKTV++ G +DI+V NA + I L + +
Sbjct: 90 EGVKCLLIAGDVGEEEFCNEAVEKTVKELGGLDILVNNAGEQHPKESIKDITSEQLHRTF 149
Query: 446 EINVKSSILLLQDMAPHLEKGSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEM 625
+ N S L + +L+ GS++I TSI + ++ Y TK A+ T+ +A +
Sbjct: 150 KTNFYSQFYLTKKAIDYLKPGSAIINTTSINPYVGNPTLIDYTATKGAINAFTRTMAQAL 209
Query: 626 GPD-TRVNAVAPG 661
D RVNAVAPG
Sbjct: 210 VKDGIRVNAVAPG 222
>sp|Q5HJP2|BUTA_STAAC Acetoin(diacetyl) reductase OS=Staphylococcus aureus
(strain COL) GN=butA PE=3 SV=1
Length = 258
Score = 89 bits (218), Expect = 4e-017
Identities = 63/186 (33%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Frame = +2
Query: 128 KVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCHVSN 307
KVA+VT QGIGF I ER +G V V + + A KL S G A I VSN
Sbjct: 5 KVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSN 64
Query: 308 AQHRRDLVEKTVQKYGKIDIVVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLLQDM 487
+ V +T ++G ++V NA P+T PI + E ++ +NV + +Q
Sbjct: 65 RDDVFNAVRQTAAQFGDFHVMVNNAGLGPTT-PIDTITEEQFKTVYGVNVAGVLWGIQAA 123
Query: 488 APHLEK---GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGPD-TRVNAVA 655
+K G +I TS AG + +++Y TK A+ GLT+ A ++ + VNA A
Sbjct: 124 HEQFKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGITVNAFA 183
Query: 656 PGFVPT 673
PG V T
Sbjct: 184 PGIVQT 189
>sp|P66775|BUTA_STAAM Acetoin(diacetyl) reductase OS=Staphylococcus aureus
(strain Mu50 / ATCC 700699) GN=butA PE=3 SV=1
Length = 258
Score = 89 bits (218), Expect = 4e-017
Identities = 63/186 (33%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Frame = +2
Query: 128 KVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCHVSN 307
KVA+VT QGIGF I ER +G V V + + A KL S G A I VSN
Sbjct: 5 KVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSN 64
Query: 308 AQHRRDLVEKTVQKYGKIDIVVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLLQDM 487
+ V +T ++G ++V NA P+T PI + E ++ +NV + +Q
Sbjct: 65 RDDVFNAVRQTAAQFGDFHVMVNNAGLGPTT-PIDTITEEQFKTVYGVNVAGVLWGIQAA 123
Query: 488 APHLEK---GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGPD-TRVNAVA 655
+K G +I TS AG + +++Y TK A+ GLT+ A ++ + VNA A
Sbjct: 124 HEQFKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGITVNAFA 183
Query: 656 PGFVPT 673
PG V T
Sbjct: 184 PGIVQT 189
>sp|P99120|BUTA_STAAN Acetoin(diacetyl) reductase OS=Staphylococcus aureus
(strain N315) GN=butA PE=1 SV=1
Length = 258
Score = 89 bits (218), Expect = 4e-017
Identities = 63/186 (33%), Positives = 91/186 (48%), Gaps = 5/186 (2%)
Frame = +2
Query: 128 KVAIVTASTQGIGFGIIERFGLEGASVVVSSRKQANVEEAVEKLKSKGIDAYGIVCHVSN 307
KVA+VT QGIGF I ER +G V V + + A KL S G A I VSN
Sbjct: 5 KVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAAALKLSSDGTKAIAIKADVSN 64
Query: 308 AQHRRDLVEKTVQKYGKIDIVVCNAAANPSTDPILSTKEAVLDKLWEINVKSSILLLQDM 487
+ V +T ++G ++V NA P+T PI + E ++ +NV + +Q
Sbjct: 65 RDDVFNAVRQTAAQFGDFHVMVNNAGLGPTT-PIDTITEEQFKTVYGVNVAGVLWGIQAA 123
Query: 488 APHLEK---GSSVIFITSIAGFQPQGSMAMYGVTKTALLGLTKALAAEMGPD-TRVNAVA 655
+K G +I TS AG + +++Y TK A+ GLT+ A ++ + VNA A
Sbjct: 124 HEQFKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFAVRGLTQVAAQDLASEGITVNAFA 183
Query: 656 PGFVPT 673
PG V T
Sbjct: 184 PGIVQT 189
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 152,217,106,747
Number of Sequences: 518415
Number of Extensions: 152217106747
Number of Successful Extensions: 938062657
Number of sequences better than 0.0: 0
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