BLASTX 7.6.2
Query= UN39762 /QuerySize=1237
(1236 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q39227|SMT2_ARATH 24-methylenesterol C-methyltransferase 2 OS... 684 4e-196
sp|Q94JS4|SMT3B_ARATH 24-methylenesterol C-methyltransferase 3 O... 624 4e-178
sp|O82427|SMT2_ORYSJ 24-methylenesterol C-methyltransferase 2 OS... 528 3e-149
sp|Q9LM02|SMT1_ARATH Cycloartenol-C-24-methyltransferase OS=Arab... 237 2e-061
sp|Q6ZIX2|SMT1_ORYSJ Cycloartenol-C-24-methyltransferase 1 OS=Or... 236 2e-061
sp|Q6BRB7|ERG6_DEBHA Sterol 24-C-methyltransferase OS=Debaryomyc... 223 3e-057
sp|Q6C2D9|ERG6_YARLI Sterol 24-C-methyltransferase OS=Yarrowia l... 220 2e-056
sp|Q6FRZ7|ERG6_CANGA Sterol 24-C-methyltransferase OS=Candida gl... 219 4e-056
sp|Q54I98|SMT1_DICDI Probable cycloartenol-C-24-methyltransferas... 219 4e-056
sp|O74198|ERG6_CANAL Sterol 24-C-methyltransferase OS=Candida al... 217 1e-055
sp|Q6CYB3|ERG6_KLULA Sterol 24-C-methyltransferase OS=Kluyveromy... 216 2e-055
sp|Q875K1|ERG6_CLAL4 Sterol 24-C-methyltransferase OS=Clavispora... 216 4e-055
sp|P25087|ERG6_YEAST Sterol 24-C-methyltransferase OS=Saccharomy... 215 9e-055
sp|Q96WX4|ERG6_PNECA Sterol 24-C-methyltransferase OS=Pneumocyst... 214 1e-054
sp|Q5EN22|ERG6_MAGGR Sterol 24-C-methyltransferase OS=Magnaporth... 212 5e-054
sp|O14321|ERG6_SCHPO Sterol 24-C-methyltransferase OS=Schizosacc... 212 6e-054
sp|Q9P3R1|ERG6_NEUCR Sterol 24-C-methyltransferase OS=Neurospora... 206 3e-052
sp|Q759S7|ERG6_ASHGO Sterol 24-C-methyltransferase OS=Ashbya gos... 201 8e-051
sp|Q9ZSK1|GTOMC_ARATH Tocopherol O-methyltransferase, chloroplas... 73 3e-012
sp|Q9C6B9|PEAM3_ARATH Putative phosphoethanolamine N-methyltrans... 69 8e-011
>sp|Q39227|SMT2_ARATH 24-methylenesterol C-methyltransferase 2 OS=Arabidopsis
thaliana GN=SMT2 PE=1 SV=2
Length = 361
Score = 684 bits (1764), Expect = 4e-196
Identities = 328/356 (92%), Positives = 344/356 (96%)
Frame = +3
Query: 54 MDNVALFFTGALVVGGIYWFLCVLGPAERKGKRALDLSGGTISAEKVQDNYKQYWSFFRR 233
MD++ LFFTGALV GIYWFLCVLGPAERKGKRA+DLSGG+ISAEKVQDNYKQYWSFFRR
Sbjct: 1 MDSLTLFFTGALVAVGIYWFLCVLGPAERKGKRAVDLSGGSISAEKVQDNYKQYWSFFRR 60
Query: 234 PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQ 413
PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSI GKSH+DATRLHEEMAVDLIQ
Sbjct: 61 PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIPGKSHKDATRLHEEMAVDLIQ 120
Query: 414 VKQGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCG 593
VK GQKILDVGCGVGGPMRAIASHSRANVVGITINEYQV RAR HN+KAGLDALCEVVCG
Sbjct: 121 VKPGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVNRARLHNKKAGLDALCEVVCG 180
Query: 594 NFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFDAENE 773
NFLQMPFDDN+FDGAYSIEATCHAPKLEEVYAEIYRVLKPGS+YVSYEWVTT+KF AE++
Sbjct: 181 NFLQMPFDDNSFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSMYVSYEWVTTEKFKAEDD 240
Query: 774 EHVEVIQGIERGDALPGLRAYSDIAEAAKKVGFEVVKEKDLAAPPAEPWWTRLKMGRLAY 953
EHVEVIQGIERGDALPGLRAY DIAE AKKVGFE+VKEKDLA+PPAEPWWTRLKMGRLAY
Sbjct: 241 EHVEVIQGIERGDALPGLRAYVDIAETAKKVGFEIVKEKDLASPPAEPWWTRLKMGRLAY 300
Query: 954 WRNHIVVQVLSAVGVAPKGTVDVHEMLFKTADFLSRGGETEIFSPMHMILCRKPIS 1121
WRNHIVVQ+LSAVGVAPKGTVDVHEMLFKTAD+L+RGGET IFSPMHMILCRKP S
Sbjct: 301 WRNHIVVQILSAVGVAPKGTVDVHEMLFKTADYLTRGGETGIFSPMHMILCRKPES 356
>sp|Q94JS4|SMT3B_ARATH 24-methylenesterol C-methyltransferase 3 OS=Arabidopsis
thaliana GN=SMT3 PE=2 SV=1
Length = 359
Score = 624 bits (1609), Expect = 4e-178
Identities = 288/354 (81%), Positives = 329/354 (92%)
Frame = +3
Query: 54 MDNVALFFTGALVVGGIYWFLCVLGPAERKGKRALDLSGGTISAEKVQDNYKQYWSFFRR 233
MD+VAL+ T L+ G +YWF+CVLGPAERKGKRA DLSGG+ISAEKV+DNY QYWSFFR+
Sbjct: 1 MDSVALYCTAGLIAGAVYWFICVLGPAERKGKRASDLSGGSISAEKVKDNYNQYWSFFRK 60
Query: 234 PKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQ 413
PKEIE+AEKVPDFVDTFYNLVTDIYEWGWGQSFHFSP + GKS +DATR+HEEMAVDLI+
Sbjct: 61 PKEIESAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPHVPGKSDKDATRIHEEMAVDLIK 120
Query: 414 VKQGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCG 593
VK GQKILD GCGVGGPMRAIA+HS+A V GITINEYQV+RA+ HN+KAGLD+LC VVCG
Sbjct: 121 VKPGQKILDAGCGVGGPMRAIAAHSKAQVTGITINEYQVQRAKLHNKKAGLDSLCNVVCG 180
Query: 594 NFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFDAENE 773
NFL+MPFD+NTFDGAYSIEATCHAPKLEEVY+EI+RV+KPGSL+VSYEWVTT+K+ ++E
Sbjct: 181 NFLKMPFDENTFDGAYSIEATCHAPKLEEVYSEIFRVMKPGSLFVSYEWVTTEKYRDDDE 240
Query: 774 EHVEVIQGIERGDALPGLRAYSDIAEAAKKVGFEVVKEKDLAAPPAEPWWTRLKMGRLAY 953
EH +VIQGIERGDALPGLR+Y+DIA AKKVGFEVVKEKDLA PP++PWW RLKMGR+AY
Sbjct: 241 EHKDVIQGIERGDALPGLRSYADIAVTAKKVGFEVVKEKDLAKPPSKPWWNRLKMGRIAY 300
Query: 954 WRNHIVVQVLSAVGVAPKGTVDVHEMLFKTADFLSRGGETEIFSPMHMILCRKP 1115
WRNH+VV +LSA+GVAPKGTVDVH+MLFKTAD+L+RGGET IFSPMHMILCRKP
Sbjct: 301 WRNHVVVVILSAIGVAPKGTVDVHKMLFKTADYLTRGGETGIFSPMHMILCRKP 354
>sp|O82427|SMT2_ORYSJ 24-methylenesterol C-methyltransferase 2 OS=Oryza sativa
subsp. japonica GN=Smt2-1 PE=2 SV=2
Length = 363
Score = 528 bits (1360), Expect = 3e-149
Identities = 247/343 (72%), Positives = 289/343 (84%), Gaps = 4/343 (1%)
Frame = +3
Query: 102 IYWFLCVLGPAERKGKRALDLSGGTISAEKVQDNYKQYWSFFRRPKEIET----AEKVPD 269
+YWF+ V+G AE KGKRA+DL G+I+ +KV+D Y QYWSFFRRPKE T AEKVP
Sbjct: 18 VYWFVWVMGAAEVKGKRAVDLKMGSITNDKVKDKYTQYWSFFRRPKETATTEASAEKVPA 77
Query: 270 FVDTFYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKQGQKILDVGC 449
FVDTFYNLVTDIYEWGWGQSFHFSPS+ G+SHR+ATR+HEE DL+Q K G ++LDVGC
Sbjct: 78 FVDTFYNLVTDIYEWGWGQSFHFSPSLPGRSHREATRVHEERVADLLQAKPGHRLLDVGC 137
Query: 450 GVGGPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTF 629
GVGGPMRAIA+HS +NVVGITINEYQV RAR HNRKAGLD+ CEVVCGNFL MPF D +F
Sbjct: 138 GVGGPMRAIAAHSGSNVVGITINEYQVNRARAHNRKAGLDSRCEVVCGNFLSMPFSDASF 197
Query: 630 DGAYSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFDAENEEHVEVIQGIERG 809
DGAYSIEATCHAP+L++VY E++RVLKPG LYVSYEWVTT + A+N EHVE I GIERG
Sbjct: 198 DGAYSIEATCHAPRLQDVYGEVFRVLKPGGLYVSYEWVTTSLYRADNPEHVEAIHGIERG 257
Query: 810 DALPGLRAYSDIAEAAKKVGFEVVKEKDLAAPPAEPWWTRLKMGRLAYWRNHIVVQVLSA 989
DALPGLR +IA AK+VGFEV+KE DLA PPA PWWTRLKMGR+AYWRN +VV+VL+
Sbjct: 258 DALPGLRRQDEIASIAKEVGFEVLKELDLALPPALPWWTRLKMGRIAYWRNSLVVRVLTM 317
Query: 990 VGVAPKGTVDVHEMLFKTADFLSRGGETEIFSPMHMILCRKPI 1118
+ +APKG +VHEML++TA L+RGGET IF+PMHM+L RKP+
Sbjct: 318 LRIAPKGVCEVHEMLYETAQHLTRGGETGIFTPMHMVLLRKPV 360
>sp|Q9LM02|SMT1_ARATH Cycloartenol-C-24-methyltransferase OS=Arabidopsis
thaliana GN=SMT1 PE=2 SV=1
Length = 336
Score = 237 bits (603), Expect = 2e-061
Identities = 117/258 (45%), Positives = 158/258 (61%), Gaps = 4/258 (1%)
Frame = +3
Query: 168 GGTISAEKV---QDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHF 338
GG I V + Y+QY F E E D V+ +Y+L T YE+GWG+SFHF
Sbjct: 8 GGKIDKSDVLTAVEKYEQY-HVFHGGNEEERKANYTDMVNKYYDLATSFYEYGWGESFHF 66
Query: 339 SPSIRGKSHRDATRLHEEMAVDLIQVKQGQKILDVGCGVGGPMRAIASHSRANVVGITIN 518
+ +G+S R++ + HE + ++ GQK+LDVGCG+GGP+R IA S + V G+ N
Sbjct: 67 AQRWKGESLRESIKRHEHFLALQLGIQPGQKVLDVGCGIGGPLREIARFSNSVVTGLNNN 126
Query: 519 EYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIY 698
EYQ+ R ++ NR AG+D C V +F++MPF +N+FD Y+IEATCHAP Y EIY
Sbjct: 127 EYQITRGKELNRLAGVDKTCNFVKADFMKMPFPENSFDAVYAIEATCHAPDAYGCYKEIY 186
Query: 699 RVLKPGSLYVSYEWVTTDKFDAENEEHVEVIQGIERGDALPGLRAYSDIAEAAKKVGFEV 878
RVLKPG + +YEW TD FD +N EH ++ IE GD LP +R + EA K+ GFEV
Sbjct: 187 RVLKPGQCFAAYEWCMTDAFDPDNAEHQKIKGEIEIGDGLPDIRLTTKCLEALKQAGFEV 246
Query: 879 VKEKDLAAPPAEPWWTRL 932
+ EKDLA PW+ L
Sbjct: 247 IWEKDLAKDSPVPWYLPL 264
>sp|Q6ZIX2|SMT1_ORYSJ Cycloartenol-C-24-methyltransferase 1 OS=Oryza sativa
subsp. japonica GN=Smt1-1 PE=2 SV=1
Length = 344
Score = 236 bits (602), Expect = 2e-061
Identities = 118/272 (43%), Positives = 165/272 (60%), Gaps = 7/272 (2%)
Frame = +3
Query: 153 ALDLS---GGTISAEKVQ---DNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEW 314
A+DL+ GG I+ ++V+ D Y++Y ++ KE D V+ +Y+L T YE+
Sbjct: 6 AMDLASGLGGKITKDEVKSAVDEYEKYHGYY-GGKEEARKSNYTDMVNKYYDLATSFYEY 64
Query: 315 GWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKQGQKILDVGCGVGGPMRAIASHSRA 494
GWG+SFHF+ G+S R++ + HE + VK G K+LDVGCG+GGP+R IA S A
Sbjct: 65 GWGESFHFAHRWNGESLRESIKRHEHFLALQLGVKPGMKVLDVGCGIGGPLREIAKFSLA 124
Query: 495 NVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKL 674
+V G+ NEYQ+ R ++ NR AG+ C+ V +F++MPF DNTFD Y+IEATCHAP
Sbjct: 125 SVTGLNNNEYQITRGKELNRVAGVSGTCDFVKADFMKMPFSDNTFDAVYAIEATCHAPDP 184
Query: 675 EEVYAEIYRVLKPGSLYVSYEWVTTDKFDAENEEHVEVIQGIERGDALPGLRAYSDIAEA 854
Y EIYRVLKPG + YEW TD ++ N H + IE G+ LP +R+ +A
Sbjct: 185 VGCYKEIYRVLKPGQCFAVYEWCITDHYEPNNATHKRIKDEIELGNGLPDIRSTQQCLQA 244
Query: 855 AKKVGFEVVKEKDLAAPPAEPWWTRLKMGRLA 950
AK GFEV+ +KDLA PW+ L R +
Sbjct: 245 AKDAGFEVIWDKDLAEDSPVPWYLPLDPSRFS 276
>sp|Q6BRB7|ERG6_DEBHA Sterol 24-C-methyltransferase OS=Debaryomyces hansenii
GN=ERG6 PE=3 SV=1
Length = 377
Score = 223 bits (566), Expect = 3e-057
Identities = 115/265 (43%), Positives = 160/265 (60%), Gaps = 3/265 (1%)
Frame = +3
Query: 135 ERKGKRALDLSGGTISAEKVQDNYKQYW-SFFRRPKEIETAEKVPDFVDTFYNLVTDIYE 311
++ G +AL +S ++E D Y ++W + E + + +YNLVTD YE
Sbjct: 28 KQTGLKAL-MSKARDASEVANDGYFKHWDGGVTKEDEDKRLSDYSNLTAHYYNLVTDFYE 86
Query: 312 WGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKQGQKILDVGCGVGGPMRAIASHSR 491
+GWG SFHFS G++ R AT HE +Q+ + K+LDVGCGVGGP R I +
Sbjct: 87 YGWGSSFHFSRYYTGEAFRQATARHEHFLAHKMQINENMKVLDVGCGVGGPAREICRFTD 146
Query: 492 ANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPK 671
++VG+ N+YQ++RA + RK LD V G+F+QM F+ +FD Y+IEAT HAP
Sbjct: 147 CSIVGLNNNDYQIERANHYARKYKLDDKLSFVKGDFMQMDFEAESFDAVYAIEATVHAPV 206
Query: 672 LEEVYAEIYRVLKPGSLYVSYEWVTTDKFDAENEEHVEVIQGIERGDALPGLRAYSDIAE 851
LE VY+EIY+VLKPG ++ YEWV TDK+D ENEEH ++ GIE GD +P + +
Sbjct: 207 LEGVYSEIYKVLKPGGVFGVYEWVMTDKYDDENEEHRKIAYGIEVGDGIPKMYKREVAEK 266
Query: 852 AAKKVGFEVVKEKDLAAPPAE-PWW 923
A K VGFE+ E DLA + PW+
Sbjct: 267 ALKSVGFEIEYEADLADKEDDIPWY 291
>sp|Q6C2D9|ERG6_YARLI Sterol 24-C-methyltransferase OS=Yarrowia lipolytica
GN=ERG6 PE=3 SV=1
Length = 381
Score = 220 bits (560), Expect = 2e-056
Identities = 105/215 (48%), Positives = 143/215 (66%), Gaps = 1/215 (0%)
Frame = +3
Query: 282 FYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKQGQKILDVGCGVGG 461
+YNLVTD YE+GWG SFHFS +G++ R AT HE + ++ G K+LDVGCGVGG
Sbjct: 82 YYNLVTDFYEYGWGSSFHFSRYYKGEAFRQATARHEHYLAYKMGIQPGMKVLDVGCGVGG 141
Query: 462 PMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAY 641
P R IA + AN+VG+ N+YQV+R ++ G V G+F+QM F DN+FD Y
Sbjct: 142 PAREIARFTGANIVGLNNNDYQVERGTHYSEVQGFGDQVTYVKGDFMQMDFPDNSFDAVY 201
Query: 642 SIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFDAENEEHVEVIQGIERGDALP 821
+IEAT HAP LE VY+EI+RVLKPG ++ YEWV TD++D N EH ++ GIE+GD +P
Sbjct: 202 AIEATVHAPVLEGVYSEIFRVLKPGGVFGVYEWVMTDEYDESNPEHRDICYGIEKGDGIP 261
Query: 822 GLRAYSDIAEAAKKVGFEVVKEKDLAAPPAE-PWW 923
+ +A + VGF++ ++DLAA AE PW+
Sbjct: 262 KMYKREVAVKALENVGFDIEYQEDLAADDAEVPWY 296
>sp|Q6FRZ7|ERG6_CANGA Sterol 24-C-methyltransferase OS=Candida glabrata GN=ERG6
PE=3 SV=1
Length = 372
Score = 219 bits (557), Expect = 4e-056
Identities = 114/269 (42%), Positives = 160/269 (59%), Gaps = 5/269 (1%)
Frame = +3
Query: 126 GPAERKGKRALDLSGGTISAEKVQDNYKQYWSFFRRPKEIE--TAEKVPDFVDTFYNLVT 299
G R G AL LS + + Y ++W + KE E E + ++YN+VT
Sbjct: 21 GAESRTGLTAL-LSKNRNAQREAVSKYLRHWD-GKTDKEAEDRRLEDYNEATHSYYNVVT 78
Query: 300 DIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKQGQKILDVGCGVGGPMRAIA 479
D YE+GWG SFHFS +G++ + A HE+ + +K+G +LDVGCGVGGP R IA
Sbjct: 79 DFYEYGWGSSFHFSRFYKGENFQAAMARHEQYLAYMAGIKKGDLVLDVGCGVGGPARTIA 138
Query: 480 SHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATC 659
+ N++G+ N+YQ+++A+ + +K L + V G+F+ M F+ N+FD Y+IEATC
Sbjct: 139 RFTGCNIIGLNNNDYQIQKAKYYAKKYNLQDHMDFVKGDFMNMEFEPNSFDKVYAIEATC 198
Query: 660 HAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFDAENEEHVEVIQGIERGDALPGLRAYS 839
HAPKLE VY EIY+VLKPG + YEWV T+ +D NEEH ++ IE GD +P +
Sbjct: 199 HAPKLEGVYGEIYKVLKPGGTFAVYEWVMTENYDENNEEHRKIAYEIELGDGIPKMFTVD 258
Query: 840 DIAEAAKKVGFEVVKEKDLAAPPAE-PWW 923
+A K VGFEV KDLA E PW+
Sbjct: 259 VAKQALKNVGFEVEVSKDLADEDDEIPWY 287
>sp|Q54I98|SMT1_DICDI Probable cycloartenol-C-24-methyltransferase 1
OS=Dictyostelium discoideum GN=smt1 PE=1 SV=1
Length = 354
Score = 219 bits (557), Expect = 4e-056
Identities = 110/255 (43%), Positives = 154/255 (60%), Gaps = 3/255 (1%)
Frame = +3
Query: 186 EKVQDNYKQYWSFFR--RPKEIETAE-KVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRG 356
+KV D Y F+ K I+ + V+TFY+L TD YE+GWGQSFHF+ +
Sbjct: 30 DKVDDTLNGYKELFKGNDDKAIQARKNNYTHMVNTFYDLATDFYEFGWGQSFHFATRHKY 89
Query: 357 KSHRDATRLHEEMAVDLIQVKQGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKR 536
+S + HE + + G K++D+GCGVGGPMR IA S ANVVG+ NEYQ++R
Sbjct: 90 ESFEASIARHEMYMAHQLGLFPGMKVIDIGCGVGGPMRTIARFSGANVVGLNNNEYQIQR 149
Query: 537 ARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPG 716
+ N AGL LC + +F+ +P +DNT+D AY IEATCHAP L +Y E++R++KPG
Sbjct: 150 GKRLNESAGLSHLCSFIKADFMHVPVEDNTYDCAYQIEATCHAPDLVGLYKEVFRIVKPG 209
Query: 717 SLYVSYEWVTTDKFDAENEEHVEVIQGIERGDALPGLRAYSDIAEAAKKVGFEVVKEKDL 896
L+ YEW+ T+KF+ E+ V + + IE G+ LP L ++I AAK GFEV+ D+
Sbjct: 210 GLFGGYEWIMTNKFNPEDPVEVNIKKQIELGNGLPDLVKPAEIINAAKAAGFEVITAFDV 269
Query: 897 AAPPAEPWWTRLKMG 941
A PW+ L G
Sbjct: 270 AETSELPWYLPLSSG 284
>sp|O74198|ERG6_CANAL Sterol 24-C-methyltransferase OS=Candida albicans GN=ERG6
PE=3 SV=1
Length = 376
Score = 217 bits (552), Expect = 1e-055
Identities = 108/250 (43%), Positives = 150/250 (60%), Gaps = 2/250 (0%)
Frame = +3
Query: 180 SAEKVQDNYKQYW-SFFRRPKEIETAEKVPDFVDTFYNLVTDIYEWGWGQSFHFSPSIRG 356
+A + Y ++W + E + +YNLVTD YE+GWG SFHFS +G
Sbjct: 41 AASVAAEGYFKHWDGGISKDDEEKRLNDYSQLTHHYYNLVTDFYEYGWGSSFHFSRYYKG 100
Query: 357 KSHRDATRLHEEMAVDLIQVKQGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKR 536
++ R AT HE + + + K+LDVGCGVGGP R I + +VG+ N+YQ++R
Sbjct: 101 EAFRQATARHEHFLAHKMNLNENMKVLDVGCGVGGPGREITRFTDCEIVGLNNNDYQIER 160
Query: 537 ARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPG 716
A + +K LD V G+F+QM F+ +FD Y+IEAT HAP LE VY+EIY+VLKPG
Sbjct: 161 ANHYAKKYHLDHKLSYVKGDFMQMDFEPESFDAVYAIEATVHAPVLEGVYSEIYKVLKPG 220
Query: 717 SLYVSYEWVTTDKFDAENEEHVEVIQGIERGDALPGLRAYSDIAEAAKKVGFEVVKEKDL 896
++ YEWV TDK+D NEEH ++ GIE GD +P + + +A K VGFE+ +KDL
Sbjct: 221 GIFGVYEWVMTDKYDETNEEHRKIAYGIEVGDGIPKMYSRKVAEQALKNVGFEIEYQKDL 280
Query: 897 AAPPAE-PWW 923
A E PW+
Sbjct: 281 ADVDDEIPWY 290
>sp|Q6CYB3|ERG6_KLULA Sterol 24-C-methyltransferase OS=Kluyveromyces lactis
GN=ERG6 PE=3 SV=1
Length = 371
Score = 216 bits (550), Expect = 2e-055
Identities = 109/266 (40%), Positives = 153/266 (57%), Gaps = 1/266 (0%)
Frame = +3
Query: 138 RKGKRALDLSGGTISAEKVQDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEWG 317
+ G AL + E V K + E E + ++YN+VTD YE+G
Sbjct: 25 KSGFSALVSKNKSAQTEAVAKYLKHWDGKTDADAERRRLEDYNESTHSYYNVVTDFYEYG 84
Query: 318 WGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKQGQKILDVGCGVGGPMRAIASHSRAN 497
WG SFHFS +G+S + HE +K+ ILDVGCGVGGP R I+ + N
Sbjct: 85 WGSSFHFSRFFKGESFSASVARHEHYLAYKAGIKENDLILDVGCGVGGPARTISRFTGCN 144
Query: 498 VVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLE 677
++G+ N+YQ+++A + ++ LD+ V G+F++M FD+NTFD Y+IEATCHAP E
Sbjct: 145 IIGLNNNDYQIQKANYYAKRDHLDSKLSFVKGDFMKMEFDENTFDSVYAIEATCHAPTFE 204
Query: 678 EVYAEIYRVLKPGSLYVSYEWVTTDKFDAENEEHVEVIQGIERGDALPGLRAYSDIAEAA 857
VY EIY+VLKPG + YEWV TDK+D N EH ++ IE GD +P + + +A
Sbjct: 205 GVYGEIYKVLKPGGTFAVYEWVMTDKYDETNPEHRKIAYEIELGDGIPKMYSVDAARDAL 264
Query: 858 KKVGFEVVKEKDLAAPPAE-PWWTRL 932
KVGFE+++E DLA E PW+ L
Sbjct: 265 SKVGFEILEENDLADNDDEIPWYAPL 290
>sp|Q875K1|ERG6_CLAL4 Sterol 24-C-methyltransferase OS=Clavispora lusitaniae
(strain ATCC 42720) GN=ERG6 PE=3 SV=1
Length = 375
Score = 216 bits (548), Expect = 4e-055
Identities = 110/264 (41%), Positives = 153/264 (57%), Gaps = 1/264 (0%)
Frame = +3
Query: 135 ERKGKRALDLSGGTISAEKVQDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEW 314
+++G AL S +K + E + + +YNLVTD YE+
Sbjct: 27 KKRGISALMAKAKEASDVATNGYFKHWDGGVSEDDEKKRLDDYSSLTKNYYNLVTDFYEY 86
Query: 315 GWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKQGQKILDVGCGVGGPMRAIASHSRA 494
GWG SFHFS +G++ R AT HE + + + ++LDVGCGVGGP R I +
Sbjct: 87 GWGSSFHFSRYYKGEAFRQATARHEHFLAHKMNINENMRVLDVGCGVGGPGREICRFTDC 146
Query: 495 NVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKL 674
+VG+ N+YQV+RA+ + +K LD V G+F+QM F+ +FD Y+IEAT HAP L
Sbjct: 147 TIVGLNNNDYQVERAQYYAKKYKLDDKLSYVKGDFMQMDFEPESFDAVYAIEATVHAPVL 206
Query: 675 EEVYAEIYRVLKPGSLYVSYEWVTTDKFDAENEEHVEVIQGIERGDALPGLRAYSDIAEA 854
E VY+EIY+VLKPG ++ YEWV TDK+D NEEH ++ GIE GD +P + +A
Sbjct: 207 EGVYSEIYKVLKPGGVFGVYEWVMTDKYDENNEEHRKIAYGIEVGDGIPKMYKREVAEQA 266
Query: 855 AKKVGFEVVKEKDLAAPPAE-PWW 923
K VGF++ EKDLA E PW+
Sbjct: 267 LKNVGFDIEYEKDLADVNDEIPWY 290
>sp|P25087|ERG6_YEAST Sterol 24-C-methyltransferase OS=Saccharomyces cerevisiae
GN=ERG6 PE=1 SV=4
Length = 383
Score = 215 bits (545), Expect = 9e-055
Identities = 113/277 (40%), Positives = 160/277 (57%), Gaps = 2/277 (0%)
Frame = +3
Query: 135 ERKGKRALDLSGGTISAEKVQDNYKQYWSFFRRPKEIETAEKVPDFVDTFYNLVTDIYEW 314
++ G AL + E VQ + + + E E + ++YN+VTD YE+
Sbjct: 24 KKTGLSALMSKNNSAQKEAVQKYLRNWDGRTDKDAEERRLEDYNEATHSYYNVVTDFYEY 83
Query: 315 GWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKQGQKILDVGCGVGGPMRAIASHSRA 494
GWG SFHFS +G+S + HE +++G +LDVGCGVGGP R IA +
Sbjct: 84 GWGSSFHFSRFYKGESFAASIARHEHYLAYKAGIQRGDLVLDVGCGVGGPAREIARFTGC 143
Query: 495 NVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKL 674
NV+G+ N+YQ+ +A+ + +K L + V G+F++M F++NTFD Y+IEATCHAPKL
Sbjct: 144 NVIGLNNNDYQIAKAKYYAKKYNLSDQMDFVKGDFMKMDFEENTFDKVYAIEATCHAPKL 203
Query: 675 EEVYAEIYRVLKPGSLYVSYEWVTTDKFDAENEEHVEVIQGIERGDALPGLRAYSDIAEA 854
E VY+EIY+VLKPG + YEWV TDK+D N EH ++ IE GD +P + +A
Sbjct: 204 EGVYSEIYKVLKPGGTFAVYEWVMTDKYDENNPEHRKIAYEIELGDGIPKMFHVDVARKA 263
Query: 855 AKKVGFEVVKEKDLAAPPAE-PWWTRLKMGRLAYWRN 962
K GFEV+ +DLA E PW+ L G Y +N
Sbjct: 264 LKNCGFEVLVSEDLADNDDEIPWYYPL-TGEWKYVQN 299
>sp|Q96WX4|ERG6_PNECA Sterol 24-C-methyltransferase OS=Pneumocystis carinii
GN=erg6 PE=2 SV=1
Length = 377
Score = 214 bits (544), Expect = 1e-054
Identities = 103/241 (42%), Positives = 155/241 (64%), Gaps = 3/241 (1%)
Frame = +3
Query: 282 FYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKQGQKILDVGCGVGG 461
+YNLVTD YE+GW SFHF + +S A HE +++G+ +LDVGCGVGG
Sbjct: 80 YYNLVTDFYEYGWSTSFHFCRFAKDESFSQAIARHEHYIALHAGIREGETVLDVGCGVGG 139
Query: 462 PMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAY 641
P I+ + AN+VG+ N+YQ++RA+ ++ K GL + + G+F+QMPF +N+FD Y
Sbjct: 140 PACQISVFTGANIVGLNNNDYQIQRAKYYSEKKGLSDKLKFIKGDFMQMPFPENSFDKIY 199
Query: 642 SIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFDAENEEHVEVIQGIERGDALP 821
SIEAT HAP LE VY+EIYRVLKPG LY SYEWV +K+D + EH +++ GIE GD++P
Sbjct: 200 SIEATIHAPSLEGVYSEIYRVLKPGGLYASYEWVMLNKYDENDPEHQQIVYGIEIGDSIP 259
Query: 822 GLRAYSDIAEAAKKVGFEVVKEKDLAAPPAE-PWWTRL--KMGRLAYWRNHIVVQVLSAV 992
+ + A KVGFE++ ++L+ + PW+ L + ++ +R+ I + ++ +
Sbjct: 260 KISKIGEAEAALIKVGFEIIHSEELSTKNSPLPWYYYLDGDLRKVRSFRDFISIARMTTI 319
Query: 993 G 995
G
Sbjct: 320 G 320
>sp|Q5EN22|ERG6_MAGGR Sterol 24-C-methyltransferase OS=Magnaporthe grisea
GN=ERG6 PE=2 SV=2
Length = 390
Score = 212 bits (539), Expect = 5e-054
Identities = 119/289 (41%), Positives = 162/289 (56%), Gaps = 14/289 (4%)
Frame = +3
Query: 198 DNYKQYWSFFRRPKEIETA----EKVPDFVD---TFYNLVTDIYEWGWGQSFHFSPSIRG 356
D Y ++W + + ET E+ D+ +YNLVTD YE+GWGQSFHF G
Sbjct: 55 DQYFRHWD--GKTAKTETTKVREERKADYATLTRQYYNLVTDFYEYGWGQSFHFCTFAPG 112
Query: 357 KSHRDATRLHEEMAVDLIQVKQGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKR 536
++ A +E I +K+G K+LD+GCGVGGP R IA + AN+ GITINEYQV+R
Sbjct: 113 ETFASAITRYEHTLAHRIGIKKGMKVLDIGCGVGGPARQIAKFTGANITGITINEYQVER 172
Query: 537 ARDHNRKAGLDA--LCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLK 710
AR + G A + V G+F+ +PF+ TFD YSIEAT HAPKLE+VY +I+ VLK
Sbjct: 173 ARRYAEMEGYGAGEQLKFVQGDFMALPFEKETFDAVYSIEATVHAPKLEDVYKQIFNVLK 232
Query: 711 PGSLYVSYEWVTTDKFDAENEEHVEVIQGIERGDALPGLRAYSDIAEAAKKVGFEVVKEK 890
PG ++ YEWV TD +D + H E+ GIE G + L+ A K GFE+++ +
Sbjct: 233 PGGIFGLYEWVMTDAYDENDPHHKEIRFGIEHGGGIANLQTAQTAIAAIKAAGFELLESE 292
Query: 891 DLA-APPAEPWWTRLKMGRLAYWRNHIVVQVLSAVGVAPKGTVDVHEML 1034
DLA PW+ L G A+ +LS + P G H +L
Sbjct: 293 DLADNSDRAPWYWPL--GGNAWQYASTFGDILSTFTMTPAGRAIAHTVL 339
>sp|O14321|ERG6_SCHPO Sterol 24-C-methyltransferase OS=Schizosaccharomyces pombe
GN=SPBC16E9.05 PE=2 SV=1
Length = 378
Score = 212 bits (538), Expect = 6e-054
Identities = 113/273 (41%), Positives = 158/273 (57%), Gaps = 13/273 (4%)
Frame = +3
Query: 144 GKRALDLSGGTISAEKVQD----NYKQYWSFFRRPKEIETAEK-------VPDFVDTFYN 290
GK A +G A K D ++Y+ F+ R E E+ E V+++Y+
Sbjct: 21 GKAAEKKTGLAAIASKDVDEQSRKLQEYFEFWDRNHENESEEDRARRIDGYKSVVNSYYD 80
Query: 291 LVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKQGQKILDVGCGVGGPMR 470
L TD+YE+GW QSFHFS +G++ + HE + +K G ++LDVGCGVGGP R
Sbjct: 81 LATDLYEYGWSQSFHFSRFYKGEAFAQSIARHEHYLAYRMGIKPGSRVLDVGCGVGGPAR 140
Query: 471 AIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIE 650
I + N+VG+ N+YQ+ R ++ K LD V G+F+ MPF+DNTFD Y+IE
Sbjct: 141 EITEFTGCNLVGLNNNDYQISRCNNYAVKRNLDKKQVFVKGDFMHMPFEDNTFDYVYAIE 200
Query: 651 ATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFDAENEEHVEVIQGIERGDALPGLR 830
AT HAP LE VY EI+RVLKPG ++ YEWV +D +D+ +H E+ IE GD +P +
Sbjct: 201 ATVHAPSLEGVYGEIFRVLKPGGVFGVYEWVMSDDYDSSIPKHREIAYNIEVGDGIPQMV 260
Query: 831 AYSDIAEAAKKVGFEVVKEKDLA--APPAEPWW 923
D EA KKVGF +++E DL P PW+
Sbjct: 261 RKCDAVEAIKKVGFNLLEEDDLTDHDNPDLPWY 293
>sp|Q9P3R1|ERG6_NEUCR Sterol 24-C-methyltransferase OS=Neurospora crassa
GN=B24P7.240 PE=3 SV=1
Length = 379
Score = 206 bits (523), Expect = 3e-052
Identities = 105/230 (45%), Positives = 142/230 (61%), Gaps = 2/230 (0%)
Frame = +3
Query: 282 FYNLVTDIYEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKQGQKILDVGCGVGG 461
+YNL TDIYE+GWGQ FHF G+S A HE I +K+ K+LDVGCGVGG
Sbjct: 82 YYNLATDIYEYGWGQCFHFCRYSPGESFYQAIARHEHYLAAQIGIKKDMKVLDVGCGVGG 141
Query: 462 PMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAY 641
P R IA + A++ G+ N+YQ+ RA + + GL + V G+F+QM F DN+FD Y
Sbjct: 142 PAREIAKFTDAHITGLNNNDYQIDRATHYAVRDGLSGQLKFVKGDFMQMSFPDNSFDAVY 201
Query: 642 SIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFDAENEEHVEVIQGIERGDALP 821
+IEAT HAPKLE VY EIYRVLKPG + YEW+ TD +D +N EH ++ IE G+ +
Sbjct: 202 AIEATVHAPKLEGVYGEIYRVLKPGGTFGVYEWLMTDNYDNDNVEHRDIRLAIEVGNGIS 261
Query: 822 GLRAYSDIAEAAKKVGFEVVKEKDLA-APPAEPWWTRLKMGRLAYWRNHI 968
+ S+ A K VGFE+V +DLA PW+ + G L Y ++++
Sbjct: 262 NMVTISEGLAAMKNVGFELVHHEDLADRNDPMPWYWPI-AGELRYMQSYL 310
>sp|Q759S7|ERG6_ASHGO Sterol 24-C-methyltransferase OS=Ashbya gossypii GN=ERG6
PE=3 SV=1
Length = 373
Score = 201 bits (511), Expect = 8e-051
Identities = 111/277 (40%), Positives = 153/277 (55%), Gaps = 8/277 (2%)
Frame = +3
Query: 135 ERKGKRALDLSGGTISAEKVQDNYKQYWSFFRRPKEIETAEKVPDF---VDTFYNLVTDI 305
ER G AL L + ++ Y ++W + E ++ D+ ++YN+VTD
Sbjct: 25 ERSGLTAL-LGKNREAQQEAVAKYLRHWDGATDAEAEE--RRLADYNESTHSYYNVVTDF 81
Query: 306 YEWGWGQSFHFSPSIRGKSHRDATRLHEEMAVDLIQVKQGQKILDVGCGVGGPMRAIASH 485
YE+GWG SFHFS G+S + HE + G +LDVGCGVGGP R IA
Sbjct: 82 YEYGWGASFHFSRFYTGESFAMSMARHEHYLAHRAGITSGDLVLDVGCGVGGPAREIARF 141
Query: 486 SRANVVGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHA 665
+ VVG+ N+YQ+ + + ++RK GL V G+F+ M F D TFD Y+IEATCHA
Sbjct: 142 TGCRVVGLNNNDYQIMKGKHYSRKLGLGDQVSYVKGDFMNMDFPDATFDKVYAIEATCHA 201
Query: 666 PKLEEVYAEIYRVLKPGSLYVSYEWVTTDKFDAENEEHVEVIQGIERGDALPGLRAYSDI 845
P E VY EIYRVLKPG ++ YEWV T+ +D N EH + IE GD +P + +
Sbjct: 202 PSFEGVYGEIYRVLKPGGVFAVYEWVMTENYDETNPEHRRIAYDIELGDGIPKMYSVKVA 261
Query: 846 AEAAKKVGFEVVKEKDLA-APPAEPWWTRLKMGRLAY 953
+A KVGFE++ ++D A PW+ L G AY
Sbjct: 262 RDALAKVGFEILVDEDRADNDDPVPWYYPL-TGEWAY 297
>sp|Q9ZSK1|GTOMC_ARATH Tocopherol O-methyltransferase, chloroplastic
OS=Arabidopsis thaliana GN=G-TMT PE=2 SV=2
Length = 348
Score = 73 bits (178), Expect = 3e-012
Identities = 45/140 (32%), Positives = 67/140 (47%), Gaps = 6/140 (4%)
Frame = +3
Query: 339 SPSIRGKSHRDA-TRLHEEM-----AVDLIQVKQGQKILDVGCGVGGPMRAIASHSRANV 500
S + H++A R+ EE D + K+ +K++DVGCG+GG R +AS A
Sbjct: 93 SVQLSDSGHKEAQIRMIEESLRFAGVTDEEEEKKIKKVVDVGCGIGGSSRYLASKFGAEC 152
Query: 501 VGITINEYQVKRARDHNRKAGLDALCEVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEE 680
+GIT++ Q KRA D L + L PF+D FD +S+E+ H P +
Sbjct: 153 IGITLSPVQAKRANDLAAAQSLAHKASFQVADALDQPFEDGKFDLVWSMESGEHMPDKAK 212
Query: 681 VYAEIYRVLKPGSLYVSYEW 740
E+ RV PG + W
Sbjct: 213 FVKELVRVAAPGGRIIIVTW 232
>sp|Q9C6B9|PEAM3_ARATH Putative phosphoethanolamine N-methyltransferase 3
OS=Arabidopsis thaliana GN=NMT3 PE=2 SV=2
Length = 490
Score = 69 bits (166), Expect = 8e-011
Identities = 38/119 (31%), Positives = 61/119 (51%), Gaps = 2/119 (1%)
Frame = +3
Query: 399 VDLIQVKQGQKILDVGCGVGGPMRAIASHSRANVVGITINEYQVKRARDHNRKAGLDALC 578
VD++ +K GQK+LDVGCG+GG +A + +VVGI ++ + A +H GL
Sbjct: 274 VDMLDLKPGQKVLDVGCGIGGGDFYMAENFDVDVVGIDLSVNMISFALEH--AIGLKCSV 331
Query: 579 EVVCGNFLQMPFDDNTFDGAYSIEATCHAPKLEEVYAEIYRVLKPGSLYVSYEWVTTDK 755
E + + + DNTFD YS + H ++ Y+ LKPG + ++ + K
Sbjct: 332 EFEVADCTKKEYPDNTFDVIYSRDTILHIQDKPALFRRFYKWLKPGGKVLITDYCRSPK 390
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 152,747,927,994
Number of Sequences: 518415
Number of Extensions: 152747927994
Number of Successful Extensions: 943738341
Number of sequences better than 0.0: 0
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