BLASTX 7.6.2
Query= UN39897 /QuerySize=1489
(1488 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O81027|HMGCL_ARATH Hydroxymethylglutaryl-CoA lyase, mitochond... 279 4e-074
sp|P97519|HMGCL_RAT Hydroxymethylglutaryl-CoA lyase, mitochondri... 199 5e-050
sp|P38060|HMGCL_MOUSE Hydroxymethylglutaryl-CoA lyase, mitochond... 198 1e-049
sp|P35915|HMGCL_CHICK Hydroxymethylglutaryl-CoA lyase OS=Gallus ... 197 2e-049
sp|Q8TB92|HMGC2_HUMAN Probable 3-hydroxymethyl-3-methylglutaryl-... 197 3e-049
sp|Q8JZS7|HMGC2_MOUSE Probable 3-hydroxymethyl-3-methylglutaryl-... 197 3e-049
sp|Q5R9E1|HMGCL_PONAB Hydroxymethylglutaryl-CoA lyase, mitochond... 196 3e-049
sp|P35914|HMGCL_HUMAN Hydroxymethylglutaryl-CoA lyase, mitochond... 195 7e-049
sp|Q8HXZ6|HMGCL_MACFA Hydroxymethylglutaryl-CoA lyase, mitochond... 195 7e-049
sp|Q29448|HMGCL_BOVIN Hydroxymethylglutaryl-CoA lyase, mitochond... 192 8e-048
sp|A8WG57|HMGC2_DANRE Probable 3-hydroxymethyl-3-methylglutaryl-... 190 4e-047
>sp|O81027|HMGCL_ARATH Hydroxymethylglutaryl-CoA lyase, mitochondrial
OS=Arabidopsis thaliana GN=HMGCL PE=1 SV=2
Length = 468
Score = 279 bits (713), Expect = 4e-074
Identities = 139/161 (86%), Positives = 150/161 (93%)
Frame = +1
Query: 832 GVQWKGAVPPSKVAHVVKALYDMGCFEISLGDTIGIGTPGTVIPMLEAVMAAVPGEKLAV 1011
G +G V PSKVA+VVK LYDMGCFEISLGDTIGIGTPG+V+PMLEAVMA VP +KLAV
Sbjct: 308 GCPVEGPVLPSKVAYVVKELYDMGCFEISLGDTIGIGTPGSVVPMLEAVMAVVPADKLAV 367
Query: 1012 HFHDTYGQALSNILVSLQMGINIVDSSVAGLGGCPYARGAPGNVATEDVVYMLNGLGVQT 1191
HFHDTYGQAL+NILVSLQMGI+IVDSS+AGLGGCPYA+GA GNVATEDVVYMLNGLGV T
Sbjct: 368 HFHDTYGQALANILVSLQMGISIVDSSIAGLGGCPYAKGASGNVATEDVVYMLNGLGVHT 427
Query: 1192 NVDLGKLIAAGDFISKHLGRPNGSKAAVALSHRITADASKL 1314
NVDLGKLIAAGDFISKHLGRPNGSKAAVAL+ RITADASK+
Sbjct: 428 NVDLGKLIAAGDFISKHLGRPNGSKAAVALNRRITADASKI 468
Score = 263 bits (672), Expect = 2e-069
Identities = 135/156 (86%), Positives = 147/156 (94%), Gaps = 1/156 (0%)
Frame = +3
Query: 378 HQLLREVPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVEATSFASPKWV 557
+++ + +PKFVKIVEVGPRDGLQNEKNIVPTSVKVELI+RLVS+GLPVVEATSF SPKWV
Sbjct: 158 NKISKGIPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIQRLVSSGLPVVEATSFVSPKWV 217
Query: 558 PQLADAKNVMDAVNTLHGATRLPVLTPNLKGFEAAVSAGAKEVAIFASASESFSLSNINC 737
PQLADAK+VMDAVNTL GA RLPVLTPNLKGF+AAVSAGAKEVAIFASASESFSLSNINC
Sbjct: 218 PQLADAKDVMDAVNTLDGA-RLPVLTPNLKGFQAAVSAGAKEVAIFASASESFSLSNINC 276
Query: 738 SIEESLLRYRAVSTAAKELSIPVRAYVSCAVGCPVE 845
+IEESLLRYR V+TAAKE S+PVR YVSC VGCPVE
Sbjct: 277 TIEESLLRYRVVATAAKEHSVPVRGYVSCVVGCPVE 312
>sp|P97519|HMGCL_RAT Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Rattus
norvegicus GN=Hmgcl PE=2 SV=1
Length = 325
Score = 199 bits (505), Expect = 5e-050
Identities = 101/160 (63%), Positives = 123/160 (76%), Gaps = 1/160 (0%)
Frame = +1
Query: 802 LSVRMYLA-RWGVQWKGAVPPSKVAHVVKALYDMGCFEISLGDTIGIGTPGTVIPMLEAV 978
+SVR Y++ G ++G V P+KVA V K LY MGC+EISLGDTIG+GTPG + ML AV
Sbjct: 162 ISVRGYVSCALGCPYEGKVSPAKVAEVAKKLYSMGCYEISLGDTIGVGTPGLMKDMLTAV 221
Query: 979 MAAVPGEKLAVHFHDTYGQALSNILVSLQMGINIVDSSVAGLGGCPYARGAPGNVATEDV 1158
+ VP LAVH HDTYGQAL+N LV+LQMG+++VDSSVAGLGGCPYA+GA GN+ATED+
Sbjct: 222 LHEVPVAALAVHCHDTYGQALANTLVALQMGVSVVDSSVAGLGGCPYAKGASGNLATEDL 281
Query: 1159 VYMLNGLGVQTNVDLGKLIAAGDFISKHLGRPNGSKAAVA 1278
VYML GLG+ T V+L KL+ AGDFI + L R SK A A
Sbjct: 282 VYMLTGLGIHTGVNLQKLLEAGDFICQALNRKTSSKVAQA 321
Score = 192 bits (487), Expect = 6e-048
Identities = 99/157 (63%), Positives = 117/157 (74%), Gaps = 1/157 (0%)
Frame = +3
Query: 396 VPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVEATSFASPKWVPQLADA 575
+PK VKIVEVGPRDGLQNEK+IVPT VK++LI L AGLPV+EATSF SPKWVPQ+AD
Sbjct: 29 LPKRVKIVEVGPRDGLQNEKSIVPTPVKIKLIDMLSEAGLPVIEATSFVSPKWVPQMADH 88
Query: 576 KNVMDAVNTLHGATRLPVLTPNLKGFEAAVSAGAKEVAIFASASESFSLSNINCSIEESL 755
+V+ + G PVLTPN+KGFE AV+AGAKEV+IF +ASE F+ N+NCSIEES
Sbjct: 89 SDVLKGIQKFPG-INYPVLTPNMKGFEEAVAAGAKEVSIFGAASELFTRKNVNCSIEESF 147
Query: 756 LRYRAVSTAAKELSIPVRAYVSCAVGCPVERSGSTFK 866
R+ V AA+ SI VR YVSCA+GCP E S K
Sbjct: 148 QRFDGVMQAARAASISVRGYVSCALGCPYEGKVSPAK 184
>sp|P38060|HMGCL_MOUSE Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Mus
musculus GN=Hmgcl PE=1 SV=1
Length = 325
Score = 198 bits (502), Expect = 1e-049
Identities = 101/160 (63%), Positives = 122/160 (76%), Gaps = 1/160 (0%)
Frame = +1
Query: 802 LSVRMYLA-RWGVQWKGAVPPSKVAHVVKALYDMGCFEISLGDTIGIGTPGTVIPMLEAV 978
+SVR Y++ G ++G V P+KVA V K LY MGC+EISLGDTIG+GTPG + ML AV
Sbjct: 162 ISVRGYVSCALGCPYEGKVSPAKVAEVAKKLYSMGCYEISLGDTIGVGTPGLMKDMLTAV 221
Query: 979 MAAVPGEKLAVHFHDTYGQALSNILVSLQMGINIVDSSVAGLGGCPYARGAPGNVATEDV 1158
M VP L VH HDT GQAL+N LV+LQMG+++VDSSVAGLGGCPYA+GA GN+ATED+
Sbjct: 222 MHEVPVTALGVHCHDTIGQALANTLVALQMGVSVVDSSVAGLGGCPYAKGASGNLATEDL 281
Query: 1159 VYMLNGLGVQTNVDLGKLIAAGDFISKHLGRPNGSKAAVA 1278
VYMLNGLG+ T V+L KL+ AGDFI + L R SK A A
Sbjct: 282 VYMLNGLGIHTGVNLQKLLEAGDFICQALNRKTSSKVAQA 321
>sp|P35915|HMGCL_CHICK Hydroxymethylglutaryl-CoA lyase OS=Gallus gallus GN=HMGCL
PE=1 SV=1
Length = 298
Score = 197 bits (500), Expect = 2e-049
Identities = 100/156 (64%), Positives = 119/156 (76%), Gaps = 1/156 (0%)
Frame = +3
Query: 399 PKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVEATSFASPKWVPQLADAK 578
P+ VK+VEVGPRDGLQNEK++VPT VK+ LI L GLPV+EATSF SP+WVPQ+AD
Sbjct: 3 PQRVKVVEVGPRDGLQNEKSVVPTPVKIRLIDMLSETGLPVIEATSFVSPRWVPQMADHA 62
Query: 579 NVMDAVNTLHGATRLPVLTPNLKGFEAAVSAGAKEVAIFASASESFSLSNINCSIEESLL 758
VM +N L G + PVLTPNLKGF+AAV+AGAKEV+IF +ASE F+ NINCSIEESL
Sbjct: 63 EVMQGINKLPGVS-YPVLTPNLKGFQAAVAAGAKEVSIFGAASELFTKKNINCSIEESLE 121
Query: 759 RYRAVSTAAKELSIPVRAYVSCAVGCPVERSGSTFK 866
R+ V AA+ SIPVR YVSC +GCP E + S K
Sbjct: 122 RFSEVMNAARAASIPVRGYVSCVLGCPYEGNISAAK 157
Score = 190 bits (482), Expect = 2e-047
Identities = 95/149 (63%), Positives = 114/149 (76%)
Frame = +1
Query: 832 GVQWKGAVPPSKVAHVVKALYDMGCFEISLGDTIGIGTPGTVIPMLEAVMAAVPGEKLAV 1011
G ++G + +KVA V K +Y MGC+EISLGD IGIGTPG++ ML AVM VP LAV
Sbjct: 146 GCPYEGNISAAKVAEVSKKMYSMGCYEISLGDRIGIGTPGSMKEMLAAVMKEVPVGALAV 205
Query: 1012 HFHDTYGQALSNILVSLQMGINIVDSSVAGLGGCPYARGAPGNVATEDVVYMLNGLGVQT 1191
H HDTYGQAL+NILV+LQMG+++VD+SVAGLGGCPYA+GA GNVATED+VYMLNGLG+ T
Sbjct: 206 HCHDTYGQALANILVALQMGVSVVDASVAGLGGCPYAQGASGNVATEDLVYMLNGLGIHT 265
Query: 1192 NVDLGKLIAAGDFISKHLGRPNGSKAAVA 1278
VDL KL+ G FI L R SK + A
Sbjct: 266 GVDLQKLMDTGTFICNALNRRTNSKVSQA 294
>sp|Q8TB92|HMGC2_HUMAN Probable 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2
OS=Homo sapiens GN=HMGCLL1 PE=2 SV=3
Length = 370
Score = 197 bits (499), Expect = 3e-049
Identities = 94/149 (63%), Positives = 118/149 (79%)
Frame = +1
Query: 832 GVQWKGAVPPSKVAHVVKALYDMGCFEISLGDTIGIGTPGTVIPMLEAVMAAVPGEKLAV 1011
G ++G++ P KV V K LY MGC+EISLGDTIG+GTPG++ MLE+VM +P LAV
Sbjct: 218 GCPYEGSITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKRMLESVMKEIPPGALAV 277
Query: 1012 HFHDTYGQALSNILVSLQMGINIVDSSVAGLGGCPYARGAPGNVATEDVVYMLNGLGVQT 1191
H HDTYGQAL+NIL +LQMGIN+VDS+V+GLGGCPYA+GA GNVATED++YMLNGLG+ T
Sbjct: 278 HCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDLIYMLNGLGLNT 337
Query: 1192 NVDLGKLIAAGDFISKHLGRPNGSKAAVA 1278
V+L K++ AGDFI K + + SK A A
Sbjct: 338 GVNLYKVMEAGDFICKAVNKTTNSKVAQA 366
Score = 186 bits (471), Expect = 4e-046
Identities = 92/155 (59%), Positives = 115/155 (74%), Gaps = 1/155 (0%)
Frame = +3
Query: 387 LREVPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVEATSFASPKWVPQL 566
L +P+FVKIVEVGPRDGLQNEK IVPT +K+E I RL GL V+E TSF S +WVPQ+
Sbjct: 71 LSGLPEFVKIVEVGPRDGLQNEKVIVPTDIKIEFINRLSQTGLSVIEVTSFVSSRWVPQM 130
Query: 567 ADAKNVMDAVNTLHGATRLPVLTPNLKGFEAAVSAGAKEVAIFASASESFSLSNINCSIE 746
AD VM ++ G R PVLTPNL+GF AV+AGA E+++F +ASESFS NINCSIE
Sbjct: 131 ADHTEVMKGIHQYPG-VRYPVLTPNLQGFHHAVAAGATEISVFGAASESFSKKNINCSIE 189
Query: 747 ESLLRYRAVSTAAKELSIPVRAYVSCAVGCPVERS 851
ES+ ++ V +A+ ++IP R YVSCA+GCP E S
Sbjct: 190 ESMGKFEEVVKSARHMNIPARGYVSCALGCPYEGS 224
>sp|Q8JZS7|HMGC2_MOUSE Probable 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2
OS=Mus musculus GN=Hmgcll1 PE=2 SV=1
Length = 343
Score = 197 bits (499), Expect = 3e-049
Identities = 96/160 (60%), Positives = 124/160 (77%), Gaps = 1/160 (0%)
Frame = +1
Query: 802 LSVRMYLA-RWGVQWKGAVPPSKVAHVVKALYDMGCFEISLGDTIGIGTPGTVIPMLEAV 978
+ VR Y++ G ++G++ P KV V K LY MGC+EISLGDTIG+GTPG++ MLE+V
Sbjct: 177 IPVRGYVSCALGCPYEGSITPQKVTEVSKRLYGMGCYEISLGDTIGVGTPGSMKMMLESV 236
Query: 979 MAAVPGEKLAVHFHDTYGQALSNILVSLQMGINIVDSSVAGLGGCPYARGAPGNVATEDV 1158
M +P LAVH HDTYGQAL+NIL +LQMGIN+VDS+V+GLGGCPYA+GA GNVATED+
Sbjct: 237 MKEIPPGALAVHCHDTYGQALANILTALQMGINVVDSAVSGLGGCPYAKGASGNVATEDL 296
Query: 1159 VYMLNGLGVQTNVDLGKLIAAGDFISKHLGRPNGSKAAVA 1278
+YMLNG+G+ T VDL K++ AG+FI K + + SK A A
Sbjct: 297 IYMLNGMGLNTGVDLYKVMEAGEFICKAVNKTTNSKVAQA 336
Score = 189 bits (479), Expect = 5e-047
Identities = 93/152 (61%), Positives = 117/152 (76%), Gaps = 1/152 (0%)
Frame = +3
Query: 396 VPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVEATSFASPKWVPQLADA 575
+P++VKIVEVGPRDGLQNEK IVPT +K+ELI +L GL V+E TSF S +WVPQ+AD
Sbjct: 44 LPEYVKIVEVGPRDGLQNEKVIVPTDIKIELINQLSQTGLSVIEVTSFVSSRWVPQMADH 103
Query: 576 KNVMDAVNTLHGATRLPVLTPNLKGFEAAVSAGAKEVAIFASASESFSLSNINCSIEESL 755
VM + G R PVLTPNL+GF+ AV+AGA E+A+F +ASESFS NINCSIEES+
Sbjct: 104 AEVMRGIRQYPG-VRYPVLTPNLQGFQHAVAAGATEIAVFGAASESFSKKNINCSIEESM 162
Query: 756 LRYRAVSTAAKELSIPVRAYVSCAVGCPVERS 851
R++ V ++A+ + IPVR YVSCA+GCP E S
Sbjct: 163 GRFQEVISSARHMDIPVRGYVSCALGCPYEGS 194
>sp|Q5R9E1|HMGCL_PONAB Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Pongo
abelii GN=HMGCL PE=2 SV=1
Length = 325
Score = 196 bits (498), Expect = 3e-049
Identities = 99/160 (61%), Positives = 123/160 (76%), Gaps = 1/160 (0%)
Frame = +1
Query: 802 LSVRMYLA-RWGVQWKGAVPPSKVAHVVKALYDMGCFEISLGDTIGIGTPGTVIPMLEAV 978
+SVR Y++ G ++G + P+KVA V K LY MGC+EISLGDTIG+GTPG + ML AV
Sbjct: 162 ISVRGYVSCALGCPYEGKISPAKVAEVTKKLYSMGCYEISLGDTIGVGTPGIMKGMLSAV 221
Query: 979 MAAVPGEKLAVHFHDTYGQALSNILVSLQMGINIVDSSVAGLGGCPYARGAPGNVATEDV 1158
M VP LAVH HDTYGQAL+N L++LQMG+++VDSSVAGLGGCPYA+GA GN+ATED+
Sbjct: 222 MQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLGGCPYAQGASGNLATEDL 281
Query: 1159 VYMLNGLGVQTNVDLGKLIAAGDFISKHLGRPNGSKAAVA 1278
VYML GLG+ T V+L KL+ AG+FI + L R SK A A
Sbjct: 282 VYMLEGLGIHTGVNLQKLLEAGNFICQALNRKTSSKVAQA 321
Score = 188 bits (475), Expect = 2e-046
Identities = 97/150 (64%), Positives = 112/150 (74%), Gaps = 1/150 (0%)
Frame = +3
Query: 396 VPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVEATSFASPKWVPQLADA 575
+PK VKIVEVGPRDGLQNEKNIV T VK++LI L AGL V+E TSF SPKWVPQ+ D
Sbjct: 29 LPKRVKIVEVGPRDGLQNEKNIVSTPVKIKLIDMLSEAGLSVIETTSFVSPKWVPQMGDH 88
Query: 576 KNVMDAVNTLHGATRLPVLTPNLKGFEAAVSAGAKEVAIFASASESFSLSNINCSIEESL 755
V+ + G PVLTPNLKGFEAAV+AGAKEVAIF +ASE F+ NINCSIEES
Sbjct: 89 TEVLKGIQKFPG-INYPVLTPNLKGFEAAVAAGAKEVAIFGAASELFTKKNINCSIEESF 147
Query: 756 LRYRAVSTAAKELSIPVRAYVSCAVGCPVE 845
R+ A+ AA+ +I VR YVSCA+GCP E
Sbjct: 148 QRFDAILKAAQSANISVRGYVSCALGCPYE 177
>sp|P35914|HMGCL_HUMAN Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Homo
sapiens GN=HMGCL PE=1 SV=2
Length = 325
Score = 195 bits (495), Expect = 7e-049
Identities = 98/160 (61%), Positives = 122/160 (76%), Gaps = 1/160 (0%)
Frame = +1
Query: 802 LSVRMYLA-RWGVQWKGAVPPSKVAHVVKALYDMGCFEISLGDTIGIGTPGTVIPMLEAV 978
+SVR Y++ G ++G + P+KVA V K Y MGC+EISLGDTIG+GTPG + ML AV
Sbjct: 162 ISVRGYVSCALGCPYEGKISPAKVAEVTKKFYSMGCYEISLGDTIGVGTPGIMKDMLSAV 221
Query: 979 MAAVPGEKLAVHFHDTYGQALSNILVSLQMGINIVDSSVAGLGGCPYARGAPGNVATEDV 1158
M VP LAVH HDTYGQAL+N L++LQMG+++VDSSVAGLGGCPYA+GA GN+ATED+
Sbjct: 222 MQEVPLAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLGGCPYAQGASGNLATEDL 281
Query: 1159 VYMLNGLGVQTNVDLGKLIAAGDFISKHLGRPNGSKAAVA 1278
VYML GLG+ T V+L KL+ AG+FI + L R SK A A
Sbjct: 282 VYMLEGLGIHTGVNLQKLLEAGNFICQALNRKTSSKVAQA 321
>sp|Q8HXZ6|HMGCL_MACFA Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Macaca
fascicularis GN=HMGCL PE=2 SV=1
Length = 325
Score = 195 bits (495), Expect = 7e-049
Identities = 98/160 (61%), Positives = 122/160 (76%), Gaps = 1/160 (0%)
Frame = +1
Query: 802 LSVRMYLA-RWGVQWKGAVPPSKVAHVVKALYDMGCFEISLGDTIGIGTPGTVIPMLEAV 978
+SVR Y++ G ++G + P+KVA V K Y MGC+EISLGDTIG+GTPG + ML AV
Sbjct: 162 ISVRGYVSCVLGCPYEGKISPAKVAEVTKKFYSMGCYEISLGDTIGVGTPGIMKDMLSAV 221
Query: 979 MAAVPGEKLAVHFHDTYGQALSNILVSLQMGINIVDSSVAGLGGCPYARGAPGNVATEDV 1158
M VP LAVH HDTYGQAL+N L++LQMG+++VDSSVAGLGGCPYA+GA GN+ATED+
Sbjct: 222 MQEVPPAALAVHCHDTYGQALANTLMALQMGVSVVDSSVAGLGGCPYAQGASGNLATEDL 281
Query: 1159 VYMLNGLGVQTNVDLGKLIAAGDFISKHLGRPNGSKAAVA 1278
VYML GLG+ T V+L KL+ AG+FI + L R SK A A
Sbjct: 282 VYMLEGLGIHTGVNLQKLLEAGNFICQALNRKTSSKVAQA 321
Score = 187 bits (474), Expect = 2e-046
Identities = 96/150 (64%), Positives = 113/150 (75%), Gaps = 1/150 (0%)
Frame = +3
Query: 396 VPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVEATSFASPKWVPQLADA 575
+PK VKIVEVGPRDGLQNEKNIV T VK++LI L AGL V+EATSF SPKWVPQ+AD
Sbjct: 29 LPKQVKIVEVGPRDGLQNEKNIVSTPVKIKLIDMLSEAGLSVIEATSFVSPKWVPQMADH 88
Query: 576 KNVMDAVNTLHGATRLPVLTPNLKGFEAAVSAGAKEVAIFASASESFSLSNINCSIEESL 755
V+ + G T PVL PNLKGFEAAV+AGAKEV+IF +ASE F+ N+NCSIEES
Sbjct: 89 AEVLKGIQKFPGIT-YPVLIPNLKGFEAAVAAGAKEVSIFGAASELFTKKNVNCSIEESF 147
Query: 756 LRYRAVSTAAKELSIPVRAYVSCAVGCPVE 845
R+ A+ AA+ +I VR YVSC +GCP E
Sbjct: 148 QRFDAILKAAQSANISVRGYVSCVLGCPYE 177
>sp|Q29448|HMGCL_BOVIN Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Bos
taurus GN=HMGCL PE=2 SV=2
Length = 325
Score = 192 bits (486), Expect = 8e-048
Identities = 97/160 (60%), Positives = 121/160 (75%), Gaps = 1/160 (0%)
Frame = +1
Query: 802 LSVRMYLA-RWGVQWKGAVPPSKVAHVVKALYDMGCFEISLGDTIGIGTPGTVIPMLEAV 978
+SVR Y++ G ++G + P+KVA V K LY MGC+EISLGDTIG+GTPG + ML AV
Sbjct: 162 ISVRGYVSCVLGCPYEGKISPAKVAEVTKKLYSMGCYEISLGDTIGVGTPGAMKDMLSAV 221
Query: 979 MAAVPGEKLAVHFHDTYGQALSNILVSLQMGINIVDSSVAGLGGCPYARGAPGNVATEDV 1158
+ VP LAVH HDTYGQAL+N L +LQMG++++DSSVAGLGGCPYA+GA GN+ATED+
Sbjct: 222 LQEVPVTALAVHCHDTYGQALANTLTALQMGVSVMDSSVAGLGGCPYAQGASGNLATEDL 281
Query: 1159 VYMLNGLGVQTNVDLGKLIAAGDFISKHLGRPNGSKAAVA 1278
VYML GLG+ T V+L KL+ AG FI + L R SK A A
Sbjct: 282 VYMLAGLGIHTGVNLQKLLEAGAFICQALNRRTNSKVAQA 321
Score = 191 bits (484), Expect = 1e-047
Identities = 98/149 (65%), Positives = 112/149 (75%), Gaps = 1/149 (0%)
Frame = +3
Query: 399 PKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVEATSFASPKWVPQLADAK 578
PK VKIVEVGPRDGLQNEKNIVPT VK++LI L AGLPVVEATSF SPKWVPQ+AD
Sbjct: 30 PKQVKIVEVGPRDGLQNEKNIVPTPVKIKLIDMLSEAGLPVVEATSFVSPKWVPQMADHA 89
Query: 579 NVMDAVNTLHGATRLPVLTPNLKGFEAAVSAGAKEVAIFASASESFSLSNINCSIEESLL 758
V+ + G PVLTPN KGF+AAV+AGAKEVAIF +ASE F+ NINCSI+ESL
Sbjct: 90 EVLKGIQKFPG-VNYPVLTPNFKGFQAAVAAGAKEVAIFGAASELFTKKNINCSIDESLQ 148
Query: 759 RYRAVSTAAKELSIPVRAYVSCAVGCPVE 845
R+ + AA+ I VR YVSC +GCP E
Sbjct: 149 RFDEILKAARAAGISVRGYVSCVLGCPYE 177
>sp|A8WG57|HMGC2_DANRE Probable 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2
OS=Danio rerio GN=hmgcll1 PE=2 SV=1
Length = 335
Score = 190 bits (480), Expect = 4e-047
Identities = 97/153 (63%), Positives = 116/153 (75%), Gaps = 1/153 (0%)
Frame = +3
Query: 387 LREVPKFVKIVEVGPRDGLQNEKNIVPTSVKVELIRRLVSAGLPVVEATSFASPKWVPQL 566
L ++P +VKIVEVGPRDGLQNEK IVPT VK++LI L GLPV+EATSF S KWV Q+
Sbjct: 36 LPKLPVYVKIVEVGPRDGLQNEKEIVPTEVKIQLIDLLSQTGLPVIEATSFVSSKWVAQM 95
Query: 567 ADAKNVMDAVNTLHGATRLPVLTPNLKGFEAAVSAGAKEVAIFASASESFSLSNINCSIE 746
AD V+ + R PVLTPN++GF+AAV+AGA EVA+F SASE+FS NINCSIE
Sbjct: 96 ADHTAVLKGIKR-SPDVRYPVLTPNIQGFQAAVAAGANEVAVFGSASETFSRKNINCSIE 154
Query: 747 ESLLRYRAVSTAAKELSIPVRAYVSCAVGCPVE 845
ESL R+ V +AAK+ IPVR YVSCA+GCP E
Sbjct: 155 ESLQRFEQVVSAAKQEGIPVRGYVSCALGCPYE 187
Score = 189 bits (478), Expect = 7e-047
Identities = 91/160 (56%), Positives = 123/160 (76%), Gaps = 1/160 (0%)
Frame = +1
Query: 802 LSVRMYLA-RWGVQWKGAVPPSKVAHVVKALYDMGCFEISLGDTIGIGTPGTVIPMLEAV 978
+ VR Y++ G ++G V PS+V V K L+++GC+E+SLGDTIG+GT G++ ML V
Sbjct: 172 IPVRGYVSCALGCPYEGQVKPSQVTKVAKRLFELGCYEVSLGDTIGVGTAGSMAEMLSDV 231
Query: 979 MAAVPGEKLAVHFHDTYGQALSNILVSLQMGINIVDSSVAGLGGCPYARGAPGNVATEDV 1158
+ VP LAVH HDTYGQAL NIL++LQMG+++VD+SVAGLGGCP+A+GA GNV+TED+
Sbjct: 232 LTEVPAGALAVHCHDTYGQALPNILIALQMGVSVVDASVAGLGGCPFAKGASGNVSTEDL 291
Query: 1159 VYMLNGLGVQTNVDLGKLIAAGDFISKHLGRPNGSKAAVA 1278
+YML+GLG++T VDL K++ AGDFI K L R SK + A
Sbjct: 292 LYMLHGLGIETGVDLLKVMEAGDFICKALNRKTNSKVSQA 331
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 155,740,548,379
Number of Sequences: 518415
Number of Extensions: 155740548379
Number of Successful Extensions: 952083542
Number of sequences better than 0.0: 0
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