BLASTX 7.6.2
Query= UN40700 /QuerySize=1262
(1261 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P41777|NOLC1_RAT Nucleolar and coiled-body phosphoprotein 1 O... 111 1e-023
sp|Q14978|NOLC1_HUMAN Nucleolar and coiled-body phosphoprotein 1... 87 3e-016
sp|Q55FI4|NOP58_DICDI Nucleolar protein 58 OS=Dictyostelium disc... 84 3e-015
sp|Q869E1|DNLI1_DICDI DNA ligase 1 OS=Dictyostelium discoideum G... 80 3e-014
sp|P36044|MNN4_YEAST Protein MNN4 OS=Saccharomyces cerevisiae GN... 80 3e-014
sp|A5E4P1|PXR1_LODEL Protein PXR1 OS=Lodderomyces elongisporus G... 79 8e-014
>sp|P41777|NOLC1_RAT Nucleolar and coiled-body phosphoprotein 1 OS=Rattus
norvegicus GN=Nolc1 PE=1 SV=1
Length = 704
Score = 111 bits (277), Expect = 1e-023
Identities = 87/261 (33%), Positives = 119/261 (45%), Gaps = 27/261 (10%)
Frame = -3
Query: 947 SLEAVEGKDESGDEVEKNASDDQKKEAAEEVKKEKKKKKKVKETDGEIEDGIKEKKKNKK 768
SL A + GD ++SD + + EE K K K K + KK +
Sbjct: 465 SLPAKQAPRAGGD----SSSDSESSSSEEEKKTPPKPPAKKKAAGAAVPKPTPVKKAAAE 520
Query: 767 EPKVEVAKEEKTDGEIEVGVKEKKKKKKTKSKAAEAETLGDEERV--SKKRKRSEPEEET 594
+ E+ ++ E KKK KSKA G V S+ K + EE
Sbjct: 521 SSSSSSSSEDSSEEE----------KKKPKSKATPKPQAGKANGVPASQNGKAGKESEEE 570
Query: 593 KEQTEDDDDDEDSK--QRKKAGEEEDMDVQETPVKQTDVQENGNVETKSTNKKSGKGLSD 420
+E TE + +K KK E D TP + ++T +T K KG
Sbjct: 571 EEDTEQNKKAAGTKPGSGKKRKHNETADEAATP-----QSKKVKLQTPNTFPKRKKG--- 622
Query: 419 SKEPKKPFQRVNVEEVVFTDDRLKDNSYWAKGGADSGYGAKAQEVLGQVRGRGFRREKTK 240
K PF+RV EE+ D R+ DNS+ AK GA +G +A +VL +G+ FR EKTK
Sbjct: 623 EKRASSPFRRVREEEIE-VDSRVADNSFDAKRGAAGDWGERANQVLKFTKGKSFRHEKTK 681
Query: 239 KKRGSYRGGEIDLQSHSVKFE 177
KKRGSYRGG I +Q +SVKF+
Sbjct: 682 KKRGSYRGGSISVQVNSVKFD 702
>sp|Q14978|NOLC1_HUMAN Nucleolar and coiled-body phosphoprotein 1 OS=Homo
sapiens GN=NOLC1 PE=1 SV=2
Length = 699
Score = 87 bits (213), Expect = 3e-016
Identities = 52/140 (37%), Positives = 76/140 (54%), Gaps = 12/140 (8%)
Frame = -3
Query: 572 DDDEDSKQRKKAGEEEDMDVQETPVKQTDVQENG--------NVETKSTNKKSGKGLSDS 417
+ +E+ +++KKA KQ + + ++T +T K KG
Sbjct: 562 NSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTFPKRKKG---E 618
Query: 416 KEPKKPFQRVNVEEVVFTDDRLKDNSYWAKGGADSGYGAKAQEVLGQVRGRGFRREKTKK 237
K PF+RV EE+ D R+ DNS+ AK GA +G +A +VL +G+ FR EKTKK
Sbjct: 619 KRASSPFRRVREEEIE-VDSRVADNSFDAKRGAAGDWGERANQVLKFTKGKSFRHEKTKK 677
Query: 236 KRGSYRGGEIDLQSHSVKFE 177
KRGSYRGG I +Q +S+KF+
Sbjct: 678 KRGSYRGGSISVQVNSIKFD 697
>sp|Q55FI4|NOP58_DICDI Nucleolar protein 58 OS=Dictyostelium discoideum GN=nop58
PE=3 SV=1
Length = 638
Score = 84 bits (205), Expect = 3e-015
Identities = 48/163 (29%), Positives = 89/163 (54%), Gaps = 10/163 (6%)
Frame = -3
Query: 947 SLEAVEGKDESGDEVEKNASDDQKKEAAEEVKKEKKKKKKVKETDGEIEDGIKEKKKNKK 768
S ++ D E EK+ + K+ V KE+KK+KK K+ + + K++K+ KK
Sbjct: 461 SSDSDSSSDSDSSEEEKSKKSKKSKKEETPVAKEEKKEKKSKKEETPVAKEEKKEKEEKK 520
Query: 767 EPKVEVAKEEKTDGEIEVGVKEKKKKKKTKSKAAEAETLGDEERVSKKRKRSEPEE---- 600
E K + K+E+ + + KE+KK+KK K + E + EE+ KK K+ E EE
Sbjct: 521 EKKDKKEKKEEKEDK-----KEEKKEKKDKKEKTEETPVAKEEKKEKKEKKEEKEEKKDK 575
Query: 599 -ETKEQTEDDDDDEDSKQRKKAGEEEDMDVQETPVKQTDVQEN 474
E KE+ E+ ++ ++ K++K + +E+ + +E K++ +E+
Sbjct: 576 KEKKEKKEEKEEKKEKKEKKSSSKEDKKEKEEKKEKKSSSKED 618
Score = 82 bits (200), Expect = 1e-014
Identities = 61/204 (29%), Positives = 100/204 (49%), Gaps = 4/204 (1%)
Frame = -3
Query: 1148 IMAKESKALSLKSEQKALLLRSIAQYLERCGFSKCFKKLLSEAEIEKKE*DSALPDLEEV 969
+ K SK S+K E++ + + A + S +++ KK P +E
Sbjct: 437 VATKSSKESSIKQEKQDVKMEE-ASSSDSDSSSDSDSSEEEKSKKSKKSKKEETPVAKEE 495
Query: 968 YGVFLKKSLEAVEGKDESGDEVEKNASDDQK-KEAAEEVKKEKKKKKKVKETDGEIEDGI 792
K E K+E ++ EK D+K K+ +E KKE+KK+KK K+ E
Sbjct: 496 KKEKKSKKEETPVAKEEKKEKEEKKEKKDKKEKKEEKEDKKEEKKEKKDKKEKTEETPVA 555
Query: 791 KEKKKNKKEPKVEVAKEEKTDGEIEVGVKEKKKKKKTKSKAAEAETLGDEERVSKKRKRS 612
KE+KK KKE K E KEEK D + + KE+K++KK K + + +E+ KK K+S
Sbjct: 556 KEEKKEKKEKKEE--KEEKKDKKEKKEKKEEKEEKKEKKEKKSSSKEDKKEKEEKKEKKS 613
Query: 611 EPEEETKEQTEDDDDDEDSKQRKK 540
+E+ K + D++ +E ++ K
Sbjct: 614 SSKEDKKRKDRDEEPEEKKSKKSK 637
Score = 81 bits (198), Expect = 2e-014
Identities = 57/186 (30%), Positives = 92/186 (49%), Gaps = 10/186 (5%)
Frame = -3
Query: 953 KKSLEAVEGKDESGDEVEKNASDDQKKEAAEEVKKEKKKKKKVKETDGEIEDGIKEKKKN 774
K+S E +D +E + SD + E +K KK KK KE ++ KEKK
Sbjct: 443 KESSIKQEKQDVKMEEASSSDSDSSSDSDSSEEEKSKKSKKSKKEETPVAKEEKKEKKSK 502
Query: 773 KKEPKVEVAKEEKTDGEIEVGVKEKKKKKKTK--SKAAEAETLGDEERVSKKRKRSEPEE 600
K+E VAKEEK + E + K+KK+KK+ K K + E +E+ + E ++
Sbjct: 503 KEE--TPVAKEEKKEKEEKKEKKDKKEKKEEKEDKKEEKKEKKDKKEKTEETPVAKEEKK 560
Query: 599 ETKEQTEDDDDDEDSKQRKKAGEEEDMDVQETPVKQTDVQENGNVETKSTNKKSGKGLSD 420
E KE+ E+ ++ +D K++K+ EE++ ++ K + ++ E K K S
Sbjct: 561 EKKEKKEEKEEKKDKKEKKEKKEEKEEKKEKKEKKSSSKEDKKEKEEKKEKK------SS 614
Query: 419 SKEPKK 402
SKE KK
Sbjct: 615 SKEDKK 620
Score = 77 bits (189), Expect = 2e-013
Identities = 50/138 (36%), Positives = 79/138 (57%), Gaps = 7/138 (5%)
Frame = -3
Query: 932 EGKDESGDEVEKNASDDQKKEAAEEVKKEKKKKKKVKETDGEIEDGIKEKK-KNKKEPKV 756
E K++ + E + ++KKE +E KKEKK KK+ KE + ++ KEKK K +K +
Sbjct: 495 EKKEKKSKKEETPVAKEEKKE--KEEKKEKKDKKEKKEEKEDKKEEKKEKKDKKEKTEET 552
Query: 755 EVAKEEKTDGEIEVGVKEKKKKKKTKSKAAEAETLGDEERVSKKRKRSEPEEETKEQTED 576
VAKEEK + + + KE+KK KK K + E + EE+ KK K+S +E+ KE+ E
Sbjct: 553 PVAKEEKKEKKEKKEEKEEKKDKKEKKEKKEEK----EEKKEKKEKKSSSKEDKKEKEEK 608
Query: 575 DDDDEDSKQRKKAGEEED 522
+ SK+ KK + ++
Sbjct: 609 KEKKSSSKEDKKRKDRDE 626
>sp|Q869E1|DNLI1_DICDI DNA ligase 1 OS=Dictyostelium discoideum GN=lig1 PE=3
SV=1
Length = 1192
Score = 80 bits (196), Expect = 3e-014
Identities = 60/185 (32%), Positives = 102/185 (55%), Gaps = 11/185 (5%)
Frame = -3
Query: 923 DESGDEVEKNASDDQKKEAAEEVKKEKKKKKKVKETD--GEIEDGIKEKKKNKKEPKVEV 750
D+ D EK++ + KE E+V K+K+KK+K K+ E E KEKK+ +K+ K E
Sbjct: 193 DDDSDN-EKDSISSKDKEYKEKVLKDKEKKEKEKKEKELKEKESKEKEKKEKEKKEKEEK 251
Query: 749 AKEEKTDGEIEVGVKEKKKKKKTKSKAAEAETLGDEERVSKKRKRSEPEEETKEQTEDDD 570
K+EK E E+ KE K KK+ + K E E L D+E+ K+ K E +E+ +++ E +
Sbjct: 252 DKKEKELKEKELKEKELKDKKEKELKEKEKE-LKDKEKKEKELKEKEKKEKEEKEKEKKE 310
Query: 569 DDEDSKQRKKAGEEEDMDVQETPVKQTDVQENGNVETKSTN-KKSGKGLSDSKEPKKPFQ 393
E + K+ E+++ +++E +K+ +++E E + T+ KK +SD F+
Sbjct: 311 KKEKELKEKEEKEKKEKELKEKELKEKELKEKELKEKELTSPKKETIDISDL------FK 364
Query: 392 RVNVE 378
R N E
Sbjct: 365 RANAE 369
>sp|P36044|MNN4_YEAST Protein MNN4 OS=Saccharomyces cerevisiae GN=MNN4 PE=2
SV=2
Length = 1178
Score = 80 bits (196), Expect = 3e-014
Identities = 48/148 (32%), Positives = 87/148 (58%), Gaps = 7/148 (4%)
Frame = -3
Query: 905 VEKNASDDQKKEAAEEVKKEKKKKKKVKETDGEIEDGIKEKKKNKKEPKVEVAKEEKTDG 726
+E+ ++KK+ EE KK+++++KK KE + + + +EKKK ++E K + +EEK
Sbjct: 1034 LEERKRREKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKQ 1093
Query: 725 EIEVGVKEKKKKKKTKSKAAEAETLGDEERVSKK----RKRSEPEEETKEQTEDDDDDED 558
E E ++KKK+++ K K E E + +E+ +KK K+ EEE K+Q E + +ED
Sbjct: 1094 EEE---EKKKKEEEEKKKQEEGEKMKNEDEENKKNEDEEKKKNEEEEKKKQEEKNKKNED 1150
Query: 557 SKQRKKAGEEEDMDVQETPVKQTDVQEN 474
+++K+ EE+ + +E KQ + N
Sbjct: 1151 EEKKKQEEEEKKKNEEEEKKKQEEGHSN 1178
Score = 72 bits (175), Expect = 8e-012
Identities = 44/137 (32%), Positives = 78/137 (56%), Gaps = 7/137 (5%)
Frame = -3
Query: 953 KKSLEAVEGKDESGDEVEKNASDDQKKEAAEEVKKEKKKKKKVKETDGEIEDGIKEKKKN 774
KK E E K + +E +K +++KK+ EE KK+++++KK KE + + + +EKKK
Sbjct: 1042 KKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKQEEEEKKKK 1101
Query: 773 KKEPKVEVAKEEKTDGEIEVGVKEKKKKKKTKSKAAEAETLGDEERVSKKRKRSEPEEET 594
++E K + + EK E E + KK + + K K E E EE K K++E EE+
Sbjct: 1102 EEEEKKKQEEGEKMKNEDE---ENKKNEDEEKKKNEEEEKKKQEE----KNKKNEDEEKK 1154
Query: 593 KEQTEDDDDDEDSKQRK 543
K++ E+ +E+ +++K
Sbjct: 1155 KQEEEEKKKNEEEEKKK 1171
Score = 70 bits (170), Expect = 3e-011
Identities = 41/134 (30%), Positives = 79/134 (58%), Gaps = 5/134 (3%)
Frame = -3
Query: 932 EGKDESGDEVEKNASDDQKKEAAEEVKKEKKKKKKVKETDGEIEDGIKEKKKNKKEPKVE 753
E K + +E +K +++KK+ EE KK+++++KK KE + + + +EKKK ++E K +
Sbjct: 1041 EKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKQEEEEKKK 1100
Query: 752 VAKEEKTDGEIEVGVKEKKKKKKTKSKAAEAETLGDEERVSK---KRKRSEPEEETKEQT 582
KEE+ + E G K K + ++ K E + +EE K K K++E EE+ K++
Sbjct: 1101 --KEEEEKKKQEEGEKMKNEDEENKKNEDEEKKKNEEEEKKKQEEKNKKNEDEEKKKQEE 1158
Query: 581 EDDDDDEDSKQRKK 540
E+ +E+ +++K+
Sbjct: 1159 EEKKKNEEEEKKKQ 1172
Score = 69 bits (166), Expect = 8e-011
Identities = 41/149 (27%), Positives = 85/149 (57%), Gaps = 7/149 (4%)
Frame = -3
Query: 887 DDQKKEAAEEVKKEKKKKKKVKETDGEIEDGIKEKKKNKKEPKVEVAKEEKTDGEIEVGV 708
+++K+ ++ ++E+KKKK+ +E + E+ K+K++ +K+ K E K++K + E +
Sbjct: 1035 EERKRREKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKKEEEEKKKQE 1094
Query: 707 KEKKKKK--KTKSKAAEAETLGDEERVSKKRKRSEPEEETKEQTEDDDDDEDSKQRKKAG 534
+E+KKKK + K K E E + +E+ +KK E+E K++ E+++ + ++ KK
Sbjct: 1095 EEEKKKKEEEEKKKQEEGEKMKNEDEENKKN-----EDEEKKKNEEEEKKKQEEKNKKNE 1149
Query: 533 EEEDMDVQETPVKQTDVQENGNVETKSTN 447
+EE +E K+ + +E E +N
Sbjct: 1150 DEEKKKQEEEEKKKNEEEEKKKQEEGHSN 1178
>sp|A5E4P1|PXR1_LODEL Protein PXR1 OS=Lodderomyces elongisporus GN=PXR1 PE=3
SV=1
Length = 345
Score = 79 bits (192), Expect = 8e-014
Identities = 53/174 (30%), Positives = 90/174 (51%), Gaps = 6/174 (3%)
Frame = -3
Query: 926 KDESGDEVEKNASDDQKKEAAEEVKKEKKKKKKVKETDGEIEDGIKEKKKNKKEPKVEVA 747
+DE EV+K+ D ++K+ +E KKEKK+KK+ KE + E K++KK KKE K +
Sbjct: 167 EDEEKREVKKSRKDIKEKKEKKE-KKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKE 225
Query: 746 KEEKTDGEIEVGVKEKKKKKKTKSKAAEAETLGDEERVSKKRKRSEPEEETKEQTEDDDD 567
K+EK + + KEKK KK+ K K + E +E+ KK K+ + E++ K++ +D D
Sbjct: 226 KKEKKEKSDKKEKKEKKDKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKDKLD 285
Query: 566 DEDS-----KQRKKAGEEEDMDVQETPVKQTDVQENGNVETKSTNKKSGKGLSD 420
E S + K + + TP+ + ++ K + K L++
Sbjct: 286 KESSNAANVESTKSLVSDSSRESTPTPIASRLSVRSKWIKQKRASVMDAKALNE 339
Score = 76 bits (185), Expect = 5e-013
Identities = 41/144 (28%), Positives = 84/144 (58%)
Frame = -3
Query: 953 KKSLEAVEGKDESGDEVEKNASDDQKKEAAEEVKKEKKKKKKVKETDGEIEDGIKEKKKN 774
K + GK+E + ++ + ++K EE ++ KK +K +KE + E K++KK
Sbjct: 139 KALISYANGKNEDKKDKDEVSLLRKRKVEDEEKREVKKSRKDIKEKKEKKEKKEKKEKKE 198
Query: 773 KKEPKVEVAKEEKTDGEIEVGVKEKKKKKKTKSKAAEAETLGDEERVSKKRKRSEPEEET 594
KKE K + K+EK + + + KEKK+KK+ K K+ + E +++ KK K+ + E++
Sbjct: 199 KKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKSDKKEKKEKKDKKEKKEKKEKKEKKE 258
Query: 593 KEQTEDDDDDEDSKQRKKAGEEED 522
K++ ++ + ++ K++K+ E++D
Sbjct: 259 KKEKKEKKEKKEKKEKKEKKEKKD 282
Score = 72 bits (175), Expect = 8e-012
Identities = 49/163 (30%), Positives = 85/163 (52%), Gaps = 8/163 (4%)
Frame = -3
Query: 983 DLEEVYGVFLKKSLEAVEGKD--ESGDEVEKNASDDQKKEAAEEVKKEKKKKKKVKETDG 810
D +EV + K+ +E E ++ +S ++++ +KKE KKEKK+KK+ KE
Sbjct: 154 DKDEV-SLLRKRKVEDEEKREVKKSRKDIKEKKEKKEKKE-----KKEKKEKKEKKEKKE 207
Query: 809 EIEDGIKEKKKNKKEPKVEVAKEEKTDGEIEVGVKEKKKKKKTKSKAAEAETLGDEERVS 630
+ E K++KK KKE K + K+EK+D + + K+KK+KK+ K K + E +E+
Sbjct: 208 KKEKKEKKEKKEKKEKKEKKEKKEKSDKKEKKEKKDKKEKKEKKEKKEKKEKKEKKEKKE 267
Query: 629 KKRKRSEPEEETKEQTEDDDDDEDSKQRKKAGEEEDMDVQETP 501
KK K+ + E++ K+ D + + D + TP
Sbjct: 268 KKEKKEKKEKKEKKDKLDKESSNAANVESTKSLVSDSSRESTP 310
Score = 70 bits (169), Expect = 4e-011
Identities = 41/121 (33%), Positives = 72/121 (59%), Gaps = 6/121 (4%)
Frame = -3
Query: 956 LKKSLEAVEGKDESGDEVEKNASDDQKKEAAEEVKKEKKKKKKVKETDGEIEDGIKEKKK 777
+KKS + ++ K E ++ EK ++K++ ++ KKEKK+KK+ KE + E K++K
Sbjct: 174 VKKSRKDIKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKS 233
Query: 776 NKKEPKVEVAKEEKTDGEIEVGVKEKKKKKKTKSKAAEAETLGDEERVSKKRKRSEPEEE 597
+KKE K + K+EK + KEKK+KK+ K K + E +E+ KK K+ + ++E
Sbjct: 234 DKKEKKEKKDKKEKKE------KKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKDKLDKE 287
Query: 596 T 594
+
Sbjct: 288 S 288
Score = 69 bits (168), Expect = 5e-011
Identities = 40/126 (31%), Positives = 69/126 (54%)
Frame = -3
Query: 953 KKSLEAVEGKDESGDEVEKNASDDQKKEAAEEVKKEKKKKKKVKETDGEIEDGIKEKKKN 774
+K ++ + K E ++ EK ++K++ ++ KKEKK+KK+ KE + E K KK
Sbjct: 178 RKDIKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKSDKKE 237
Query: 773 KKEPKVEVAKEEKTDGEIEVGVKEKKKKKKTKSKAAEAETLGDEERVSKKRKRSEPEEET 594
KKE K + K+EK + + + KEKK+KK+ K K + E ++++ K+ + E T
Sbjct: 238 KKEKKDKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKEKKDKLDKESSNAANVEST 297
Query: 593 KEQTED 576
K D
Sbjct: 298 KSLVSD 303
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 156,274,146,103
Number of Sequences: 518415
Number of Extensions: 156274146103
Number of Successful Extensions: 960041085
Number of sequences better than 0.0: 0
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