BLASTX 7.6.2
Query= UN40823 /QuerySize=1210
(1209 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos ... 87 3e-016
sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo... 86 5e-016
sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=R... 84 1e-015
sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN... 84 2e-015
sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Dani... 84 2e-015
sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus ... 82 7e-015
sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus... 82 7e-015
sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo... 81 2e-014
sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN... 81 2e-014
sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus ... 79 4e-014
sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropica... 77 2e-013
sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevi... 76 4e-013
sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevi... 76 5e-013
sp|Q8NG27|PJA1_HUMAN E3 ubiquitin-protein ligase Praja-1 OS=Homo... 74 2e-012
sp|O55176|PJA1_MOUSE E3 ubiquitin-protein ligase Praja-1 OS=Mus ... 74 2e-012
sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabido... 72 5e-012
sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabido... 72 5e-012
sp|O43164|PJA2_HUMAN E3 ubiquitin-protein ligase Praja-2 OS=Homo... 70 4e-011
sp|Q9VE61|RN181_DROME E3 ubiquitin-protein ligase CG7694 OS=Dros... 69 5e-011
sp|Q9C1X4|YKW3_SCHPO Uncharacterized RING finger protein P32A8.0... 64 3e-009
>sp|Q3T0W3|RN181_BOVIN E3 ubiquitin-protein ligase RNF181 OS=Bos taurus
GN=RNF181 PE=2 SV=1
Length = 153
Score = 87 bits (213), Expect = 3e-016
Identities = 44/84 (52%), Positives = 53/84 (63%), Gaps = 5/84 (5%)
Frame = +2
Query: 638 PARKEAVENLPTVKI---CEPLQCSVCLDDFDKGSEATEMPCKHKFHVGCIVPWLELHSS 808
PA K AVENLP I L+C VCL +F++ A EMPC H FH CI+PWL +S
Sbjct: 53 PAAKTAVENLPRTVIRGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSNCILPWLSKTNS 112
Query: 809 CPVCRYELPPDDD--DEVKTDLVR 874
CP+CR+ELP DDD +E K D R
Sbjct: 113 CPLCRHELPTDDDTYEEHKRDKAR 136
>sp|Q9P0P0|RN181_HUMAN E3 ubiquitin-protein ligase RNF181 OS=Homo sapiens
GN=RNF181 PE=1 SV=1
Length = 153
Score = 86 bits (211), Expect = 5e-016
Identities = 43/84 (51%), Positives = 52/84 (61%), Gaps = 5/84 (5%)
Frame = +2
Query: 638 PARKEAVENLPTVKI---CEPLQCSVCLDDFDKGSEATEMPCKHKFHVGCIVPWLELHSS 808
PA K VENLP I L+C VCL +F++ A EMPC H FH CI+PWL +S
Sbjct: 53 PAAKTVVENLPRTVIRGSQAELKCPVCLLEFEEEETAIEMPCHHLFHSSCILPWLSKTNS 112
Query: 809 CPVCRYELPPDDD--DEVKTDLVR 874
CP+CRYELP DDD +E + D R
Sbjct: 113 CPLCRYELPTDDDTYEEHRRDKAR 136
>sp|Q0II22|RN126_BOVIN RING finger protein 126 OS=Bos taurus GN=RNF126 PE=2
SV=1
Length = 313
Score = 84 bits (207), Expect = 1e-015
Identities = 38/73 (52%), Positives = 45/73 (61%), Gaps = 5/73 (6%)
Frame = +2
Query: 629 GTLPARKEAVENLPTVKICEP-----LQCSVCLDDFDKGSEATEMPCKHKFHVGCIVPWL 793
G PA KE ++ LPTV + E L+C VC DD+ G ++PC H FH GCIVPWL
Sbjct: 204 GPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDYGLGEHVRQLPCNHLFHDGCIVPWL 263
Query: 794 ELHSSCPVCRYEL 832
E H SCPVCR L
Sbjct: 264 EQHDSCPVCRKSL 276
>sp|Q9BV68|RN126_HUMAN RING finger protein 126 OS=Homo sapiens GN=RNF126 PE=1
SV=1
Length = 326
Score = 84 bits (206), Expect = 2e-015
Identities = 38/73 (52%), Positives = 45/73 (61%), Gaps = 5/73 (6%)
Frame = +2
Query: 629 GTLPARKEAVENLPTVKICEP-----LQCSVCLDDFDKGSEATEMPCKHKFHVGCIVPWL 793
G PA KE ++ LPTV + E L+C VC DD+ G ++PC H FH GCIVPWL
Sbjct: 201 GPPPADKEKIQALPTVPVTEEHVGSGLECPVCKDDYALGERVRQLPCNHLFHDGCIVPWL 260
Query: 794 ELHSSCPVCRYEL 832
E H SCPVCR L
Sbjct: 261 EQHDSCPVCRKSL 273
>sp|Q7ZW78|RN181_DANRE E3 ubiquitin-protein ligase RNF181 OS=Danio rerio
GN=rnf181 PE=2 SV=2
Length = 156
Score = 84 bits (205), Expect = 2e-015
Identities = 42/88 (47%), Positives = 54/88 (61%), Gaps = 7/88 (7%)
Frame = +2
Query: 638 PARKEAVENLPTVKIC-----EPLQCSVCLDDFDKGSEATEMPCKHKFHVGCIVPWLELH 802
PA K V++LP V I + ++C VCL +F++ EMPCKH FH GCI+PWL
Sbjct: 54 PAAKAVVQSLPVVIISPEQADKGVKCPVCLLEFEEQESVREMPCKHLFHTGCILPWLNKT 113
Query: 803 SSCPVCRYELPPD--DDDEVKTDLVRPR 880
+SCP+CR ELP D D +E K D R R
Sbjct: 114 NSCPLCRLELPTDNADYEEFKKDKERRR 141
>sp|Q9CY62|RN181_MOUSE E3 ubiquitin-protein ligase RNF181 OS=Mus musculus
GN=Rnf181 PE=2 SV=1
Length = 165
Score = 82 bits (201), Expect = 7e-015
Identities = 41/84 (48%), Positives = 50/84 (59%), Gaps = 5/84 (5%)
Frame = +2
Query: 638 PARKEAVENLPTVKICE---PLQCSVCLDDFDKGSEATEMPCKHKFHVGCIVPWLELHSS 808
PA K VE+LP I L+C VCL +F+ EMPC H FH CI+PWL +S
Sbjct: 65 PAAKAVVESLPRTVISSAKADLKCPVCLLEFEAEETVIEMPCHHLFHSNCILPWLSKTNS 124
Query: 809 CPVCRYELPPDDD--DEVKTDLVR 874
CP+CR+ELP DDD +E K D R
Sbjct: 125 CPLCRHELPTDDDSYEEHKKDKAR 148
>sp|Q6AXU4|RN181_RAT E3 ubiquitin-protein ligase RNF181 OS=Rattus norvegicus
GN=Rnf181 PE=1 SV=1
Length = 165
Score = 82 bits (201), Expect = 7e-015
Identities = 41/84 (48%), Positives = 51/84 (60%), Gaps = 5/84 (5%)
Frame = +2
Query: 638 PARKEAVENLPTVKICE---PLQCSVCLDDFDKGSEATEMPCKHKFHVGCIVPWLELHSS 808
PA K VE+LP I L+C VCL +F++ EMPC H FH CI+PWL +S
Sbjct: 65 PAAKAVVESLPRTVIRSSKAELKCPVCLLEFEEEETVIEMPCHHLFHSNCILPWLSKTNS 124
Query: 809 CPVCRYELPPDDD--DEVKTDLVR 874
CP+CR+ELP DDD +E K D R
Sbjct: 125 CPLCRHELPTDDDSYEEHKKDKAR 148
>sp|Q9Y4L5|RN115_HUMAN E3 ubiquitin-protein ligase RNF115 OS=Homo sapiens
GN=RNF115 PE=1 SV=2
Length = 304
Score = 81 bits (198), Expect = 2e-014
Identities = 36/77 (46%), Positives = 47/77 (61%), Gaps = 5/77 (6%)
Frame = +2
Query: 629 GTLPARKEAVENLPTVKICEP-----LQCSVCLDDFDKGSEATEMPCKHKFHVGCIVPWL 793
G PA KE + +LPTV + + L+C VC +D+ E ++PC H FH CIVPWL
Sbjct: 200 GPPPADKEKITSLPTVTVTQEQVDMGLECPVCKEDYTVEEEVRQLPCNHFFHSSCIVPWL 259
Query: 794 ELHSSCPVCRYELPPDD 844
ELH +CPVCR L +D
Sbjct: 260 ELHDTCPVCRKSLNGED 276
>sp|Q91YL2|RN126_MOUSE RING finger protein 126 OS=Mus musculus GN=Rnf126 PE=1
SV=1
Length = 313
Score = 81 bits (198), Expect = 2e-014
Identities = 42/111 (37%), Positives = 57/111 (51%), Gaps = 5/111 (4%)
Frame = +2
Query: 629 GTLPARKEAVENLPTVKICEP-----LQCSVCLDDFDKGSEATEMPCKHKFHVGCIVPWL 793
G PA KE ++ LPTV + E L+C VC +D+ G ++PC H FH CIVPWL
Sbjct: 203 GPPPADKEKIQALPTVPVTEEHVGSGLECPVCKEDYALGESVRQLPCNHLFHDSCIVPWL 262
Query: 794 ELHSSCPVCRYELPPDDDDEVKTDLVRPRATSVEEINTSNENVEEDARNTS 946
E H SCPVCR L + L +S ++S+ E+A + S
Sbjct: 263 EQHDSCPVCRKSLTGQNTATNPPGLTGVGFSSSSSSSSSSSPSNENATSNS 313
>sp|Q9D0C1|RN115_MOUSE E3 ubiquitin-protein ligase RNF115 OS=Mus musculus
GN=Rnf115 PE=1 SV=1
Length = 305
Score = 79 bits (194), Expect = 4e-014
Identities = 35/77 (45%), Positives = 47/77 (61%), Gaps = 5/77 (6%)
Frame = +2
Query: 629 GTLPARKEAVENLPTVKICEP-----LQCSVCLDDFDKGSEATEMPCKHKFHVGCIVPWL 793
G PA KE + +LPTV + + L+C VC +D+ + ++PC H FH CIVPWL
Sbjct: 201 GPPPADKEKITSLPTVTVTQEQVNTGLECPVCKEDYTVEEKVRQLPCNHFFHSSCIVPWL 260
Query: 794 ELHSSCPVCRYELPPDD 844
ELH +CPVCR L +D
Sbjct: 261 ELHDTCPVCRKSLNGED 277
>sp|Q6DIP3|RN126_XENTR RING finger protein 126 OS=Xenopus tropicalis GN=rnf126
PE=2 SV=1
Length = 311
Score = 77 bits (188), Expect = 2e-013
Identities = 33/73 (45%), Positives = 44/73 (60%), Gaps = 5/73 (6%)
Frame = +2
Query: 629 GTLPARKEAVENLPTVKICEP-----LQCSVCLDDFDKGSEATEMPCKHKFHVGCIVPWL 793
G PA E ++ LPT++I E L+C VC +D+ G ++PC H FH CI+PWL
Sbjct: 199 GPPPADTEKIQALPTIQITEEHVGSGLECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWL 258
Query: 794 ELHSSCPVCRYEL 832
E H +CPVCR L
Sbjct: 259 EQHDTCPVCRKSL 271
>sp|Q6IRP0|R126B_XENLA RING finger protein 126-B OS=Xenopus laevis GN=rnf126-b
PE=2 SV=1
Length = 312
Score = 76 bits (186), Expect = 4e-013
Identities = 38/113 (33%), Positives = 59/113 (52%), Gaps = 8/113 (7%)
Frame = +2
Query: 629 GTLPARKEAVENLPTVKICEP-----LQCSVCLDDFDKGSEATEMPCKHKFHVGCIVPWL 793
G PA + ++ LPT++I E L+C VC +D+ G ++PC H FH CI+PWL
Sbjct: 200 GPPPADTDKIQALPTIQITEEHVGFGLECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWL 259
Query: 794 ELHSSCPVCRYELPPDD---DDEVKTDLVRPRATSVEEINTSNENVEEDARNT 943
E H +CPVCR L + + TD+ +++ +TS + A N+
Sbjct: 260 EQHDTCPVCRKSLSGQNTATNPPGLTDMTFSSSSTSSSSSTSPTDENNTANNS 312
>sp|Q7T0Q3|R126A_XENLA RING finger protein 126-A OS=Xenopus laevis GN=rnf126-a
PE=2 SV=1
Length = 312
Score = 76 bits (185), Expect = 5e-013
Identities = 33/73 (45%), Positives = 44/73 (60%), Gaps = 5/73 (6%)
Frame = +2
Query: 629 GTLPARKEAVENLPTVKICEP-----LQCSVCLDDFDKGSEATEMPCKHKFHVGCIVPWL 793
G PA E ++ LPT++I E L+C VC +D+ G ++PC H FH CI+PWL
Sbjct: 200 GPPPADNEKIQALPTIQITEEHVGSGLECPVCKEDYTVGECVRQLPCNHLFHNDCIIPWL 259
Query: 794 ELHSSCPVCRYEL 832
E H +CPVCR L
Sbjct: 260 EQHDTCPVCRKSL 272
>sp|Q8NG27|PJA1_HUMAN E3 ubiquitin-protein ligase Praja-1 OS=Homo sapiens
GN=PJA1 PE=1 SV=2
Length = 643
Score = 74 bits (180), Expect = 2e-012
Identities = 39/107 (36%), Positives = 57/107 (53%), Gaps = 13/107 (12%)
Frame = +2
Query: 539 EDEHSQFVRTRLAHLIEHLANNNDPIRIRHGTLPARKEAVENLPTVKICE-------PLQ 697
E+ +Q + T LAHL E LA + + PA KE+++ LP + + E +
Sbjct: 541 EERLAQAMETALAHL-ESLA-----VDVEVANPPASKESIDALPEILVTEDHGAVGQEMC 594
Query: 698 CSVCLDDFDKGSEATEMPCKHKFHVGCIVPWLELHSSCPVCRYELPP 838
C +C ++ KG ATE+PC H FH C+ WL+ +CPVCR PP
Sbjct: 595 CPICCSEYVKGEVATELPCHHYFHKPCVSIWLQKSGTCPVCRCMFPP 641
>sp|O55176|PJA1_MOUSE E3 ubiquitin-protein ligase Praja-1 OS=Mus musculus
GN=Pja1 PE=1 SV=3
Length = 578
Score = 74 bits (180), Expect = 2e-012
Identities = 39/107 (36%), Positives = 57/107 (53%), Gaps = 13/107 (12%)
Frame = +2
Query: 539 EDEHSQFVRTRLAHLIEHLANNNDPIRIRHGTLPARKEAVENLPTVKICE-------PLQ 697
E+ +Q + T LAHL E LA + + PA KE+++ LP + + E +
Sbjct: 476 EERLAQAMETALAHL-ESLA-----VDVEVANPPASKESIDALPEILVTEDHGAVGQEMC 529
Query: 698 CSVCLDDFDKGSEATEMPCKHKFHVGCIVPWLELHSSCPVCRYELPP 838
C +C ++ KG ATE+PC H FH C+ WL+ +CPVCR PP
Sbjct: 530 CPICCSEYVKGEVATELPCHHYFHKPCVSIWLQKSGTCPVCRCMFPP 576
>sp|Q8RXD3|AIP2_ARATH E3 ubiquitin-protein ligase AIP2 OS=Arabidopsis thaliana
GN=AIP2 PE=1 SV=1
Length = 310
Score = 72 bits (176), Expect = 5e-012
Identities = 31/75 (41%), Positives = 44/75 (58%), Gaps = 3/75 (4%)
Frame = +2
Query: 695 QCSVCLDDFDKGSEATEMPCKHKFHVGCIVPWLELHSSCPVCRYELPPDDDDEVKTDLVR 874
+C +C ++ G + E+PCKH FH C+ PWL+ H+SCP+CR+ELP DD K + +
Sbjct: 229 ECCICKENLVIGDKMQELPCKHTFHPPCLKPWLDEHNSCPICRHELPTDDQ---KYENWK 285
Query: 875 PRATSVEEINTSNEN 919
R EE EN
Sbjct: 286 EREKEAEEERKGAEN 300
>sp|Q9SPL2|CIP8_ARATH E3 ubiquitin-protein ligase CIP8 OS=Arabidopsis thaliana
GN=CIP8 PE=1 SV=1
Length = 334
Score = 72 bits (176), Expect = 5e-012
Identities = 38/106 (35%), Positives = 54/106 (50%), Gaps = 10/106 (9%)
Frame = +2
Query: 623 RHGTLPARKEAVENLPTVKICEP-----LQCSVCLDDFDKGSEATEMPCKHKFHVGCIVP 787
R G PA K A+E L T ++ + C+VC D G ++PC H +H CIVP
Sbjct: 227 RRGAPPAAKSAIEALETFEVSSSEGEMVMVCAVCKDGMVMGETGKKLPCGHCYHGDCIVP 286
Query: 788 WLELHSSCPVCRYELPPDD-----DDEVKTDLVRPRATSVEEINTS 910
WL +SCPVCR++L DD + + +T V A + +TS
Sbjct: 287 WLGTRNSCPVCRFQLETDDAEYEEERKKRTSTVSDSAAASSSSSTS 332
>sp|O43164|PJA2_HUMAN E3 ubiquitin-protein ligase Praja-2 OS=Homo sapiens
GN=PJA2 PE=1 SV=4
Length = 708
Score = 70 bits (169), Expect = 4e-011
Identities = 38/107 (35%), Positives = 54/107 (50%), Gaps = 13/107 (12%)
Frame = +2
Query: 539 EDEHSQFVRTRLAHLIEHLANNNDPIRIRHGTLPARKEAVENLPTVKICEPLQ------- 697
E+ +Q + T LAHL E LA + + PA KE+++ LP + E
Sbjct: 580 EERLAQAMETALAHL-ESLA-----VDVEVANPPASKESIDGLPETLVLEDHTAIGQEQC 633
Query: 698 CSVCLDDFDKGSEATEMPCKHKFHVGCIVPWLELHSSCPVCRYELPP 838
C +C ++ K ATE+PC H FH C+ WL+ +CPVCR PP
Sbjct: 634 CPICCSEYIKDDIATELPCHHFFHKPCVSIWLQKSGTCPVCRRHFPP 680
>sp|Q9VE61|RN181_DROME E3 ubiquitin-protein ligase CG7694 OS=Drosophila
melanogaster GN=CG7694 PE=2 SV=1
Length = 147
Score = 69 bits (168), Expect = 5e-011
Identities = 32/73 (43%), Positives = 46/73 (63%), Gaps = 5/73 (6%)
Frame = +2
Query: 641 ARKEAVENLPTVKICE-----PLQCSVCLDDFDKGSEATEMPCKHKFHVGCIVPWLELHS 805
A K A+ LP +I + L+CSVC + ++G + +PCKH+FH CI+ WL+ +
Sbjct: 46 ASKRAILELPVHEIVKSDEGGDLECSVCKEPAEEGQKYRILPCKHEFHEECILLWLKKTN 105
Query: 806 SCPVCRYELPPDD 844
SCP+CRYEL DD
Sbjct: 106 SCPLCRYELETDD 118
>sp|Q9C1X4|YKW3_SCHPO Uncharacterized RING finger protein P32A8.03c
OS=Schizosaccharomyces pombe GN=SPAP32A8.03c PE=2 SV=1
Length = 513
Score = 64 bits (153), Expect = 3e-009
Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 8/131 (6%)
Frame = +2
Query: 572 LAHLIEHLANNNDPIRIRHGTLPARKEAVENLPTVKICEPLQCSVCLDDFDKGSEATEMP 751
++ L+E +N P + K V+ P I E +C++C++ F + ++P
Sbjct: 356 ISQLMEQAQGHNAPAPAPEDVIAKMK--VQKPPKELIDEEGECTICMEMFKINDDVIQLP 413
Query: 752 CKHKFHVGCIVPWLELHSSCPVCRYELPPDDDDEVKTDLVRPRATSVEEINTSNE-NVEE 928
CKH FH CI PWL ++ +C +CR + P+ T S N SN N
Sbjct: 414 CKHYFHENCIKPWLRVNGTCAICRAPVDPNSQQRNNTS-----TDSANGHNPSNHANPST 468
Query: 929 DARNTSGSERR 961
N G+ R
Sbjct: 469 STTNDQGATLR 479
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 159,249,259,203
Number of Sequences: 518415
Number of Extensions: 159249259203
Number of Successful Extensions: 968868021
Number of sequences better than 0.0: 0
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