BLASTX 7.6.2
Query= UN41130 /QuerySize=1301
(1300 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q94JW0|DOHH_ARATH Deoxyhypusine hydroxylase OS=Arabidopsis th... 533 2e-150
sp|Q2QXB3|DOHH1_ORYSJ Deoxyhypusine hydroxylase-A OS=Oryza sativ... 417 1e-115
sp|Q2QLW3|DOHH2_ORYSJ Deoxyhypusine hydroxylase-B OS=Oryza sativ... 414 1e-114
sp|Q5ZIP3|DOHH_CHICK Deoxyhypusine hydroxylase OS=Gallus gallus ... 260 2e-068
sp|Q5PPJ4|DOHH_RAT Deoxyhypusine hydroxylase OS=Rattus norvegicu... 260 3e-068
sp|Q7ZUX6|DOHH_DANRE Deoxyhypusine hydroxylase OS=Danio rerio GN... 258 1e-067
sp|Q99LN9|DOHH_MOUSE Deoxyhypusine hydroxylase OS=Mus musculus G... 257 2e-067
sp|Q9BU89|DOHH_HUMAN Deoxyhypusine hydroxylase OS=Homo sapiens G... 255 9e-067
sp|Q0VC53|DOHH_BOVIN Deoxyhypusine hydroxylase OS=Bos taurus GN=... 252 6e-066
sp|Q66KT3|DOHH_XENLA Deoxyhypusine hydroxylase OS=Xenopus laevis... 249 4e-065
sp|Q9V9U4|DOHH_DROME Deoxyhypusine hydroxylase OS=Drosophila mel... 230 2e-059
sp|Q297S2|DOHH_DROPS Deoxyhypusine hydroxylase OS=Drosophila pse... 227 2e-058
sp|Q9P6K9|DOHH_SCHPO Deoxyhypusine hydroxylase OS=Schizosaccharo... 216 3e-055
sp|Q6CHJ7|DOHH_YARLI Deoxyhypusine hydroxylase OS=Yarrowia lipol... 211 1e-053
sp|Q59Z14|DOHH_CANAL Deoxyhypusine hydroxylase OS=Candida albica... 208 9e-053
sp|Q6FUV3|DOHH_CANGA Deoxyhypusine hydroxylase OS=Candida glabra... 198 1e-049
sp|P47120|DOHH_YEAST Deoxyhypusine hydroxylase OS=Saccharomyces ... 193 4e-048
sp|Q6CV81|DOHH_KLULA Deoxyhypusine hydroxylase OS=Kluyveromyces ... 190 3e-047
>sp|Q94JW0|DOHH_ARATH Deoxyhypusine hydroxylase OS=Arabidopsis thaliana
GN=At3g58180 PE=2 SV=1
Length = 314
Score = 533 bits (1371), Expect = 2e-150
Identities = 277/312 (88%), Positives = 295/312 (94%), Gaps = 4/312 (1%)
Frame = -3
Query: 1187 DGGVS---KLEKFLCERLLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAH 1017
+G VS LEKFLCERL+DQSQPISERFRALFSLRNLKGP PRNALILASRDSSNLLAH
Sbjct: 4 NGSVSSMVNLEKFLCERLVDQSQPISERFRALFSLRNLKGPGPRNALILASRDSSNLLAH 63
Query: 1016 EAAFALGQMQDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPA 837
EAAFALGQMQDAEA+PALESVLNDMSLHPIVRHEAAEALGAIGLAGN ILKKSL DPA
Sbjct: 64 EAAFALGQMQDAEAIPALESVLNDMSLHPIVRHEAAEALGAIGLAGNVNILKKSLSSDPA 123
Query: 836 QEVRETCELALKRIEELSSVDAEKN*SDSTERSPFMSVDPAAPAAAFSSVHQLREILMDE 657
QEVRETCELALKRIE++S+VDAE N S +TE+SPFMSVDPA PAA+FSSVHQLR++L+DE
Sbjct: 124 QEVRETCELALKRIEDMSNVDAE-NQSSTTEKSPFMSVDPAGPAASFSSVHQLRQVLLDE 182
Query: 656 TKGMYERYAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALDTLSKI 477
TKGMYERYAALFALRNHGGEEAVSAIVDSLSA SALLRHEVAYVLGQLQ+K AL TLSK+
Sbjct: 183 TKGMYERYAALFALRNHGGEEAVSAIVDSLSASSALLRHEVAYVLGQLQSKTALATLSKV 242
Query: 476 LRDLNEHPMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGKS 297
LRD+NEHPMVRHEAAEALGSIADEQSIALL+EFS+DPEPIV+QSCEVALSMLEFENSGKS
Sbjct: 243 LRDVNEHPMVRHEAAEALGSIADEQSIALLEEFSKDPEPIVAQSCEVALSMLEFENSGKS 302
Query: 296 FEFFFTQDPLVH 261
FEFFFTQDPLVH
Sbjct: 303 FEFFFTQDPLVH 314
>sp|Q2QXB3|DOHH1_ORYSJ Deoxyhypusine hydroxylase-A OS=Oryza sativa subsp.
japonica GN=Os12g0163300 PE=2 SV=1
Length = 319
Score = 417 bits (1071), Expect = 1e-115
Identities = 221/316 (69%), Positives = 260/316 (82%), Gaps = 4/316 (1%)
Frame = -3
Query: 1202 ASPTEDGGVSKLEKFLCERLLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLL 1023
A+ + G ++EKFLC+ LLD +QPI+ERFRALFSLRNL G PR AL+ A+RDSSNLL
Sbjct: 7 AASSTFGPTPEMEKFLCDLLLDTAQPIAERFRALFSLRNLHGDGPRCALLQAARDSSNLL 66
Query: 1022 AHEAAFALGQMQDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILD 843
AHEAAFALGQMQDAEA+PALE+VL D+SLHPIVRHEAAEALGAIGL + +L++SL D
Sbjct: 67 AHEAAFALGQMQDAEAIPALEAVLKDLSLHPIVRHEAAEALGAIGLEKSIPLLEESLAAD 126
Query: 842 PAQEVRETCELALKRIEELSSVDAEKN*SDSTERSPFMSVDPAAPAAAFSSVHQLREILM 663
PA EV+ETCELAL+RIE+ + S+ST SPF+SVDPA PA SVHQLREIL+
Sbjct: 127 PAVEVQETCELALRRIEQQKNAGV----SESTTISPFLSVDPALPAKQGLSVHQLREILL 182
Query: 662 DETKGMYERYAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALDTLS 483
+E + MYERYAALFALRN + AVSAIV +L A SALL+HEVAYVLGQLQNKAA D LS
Sbjct: 183 NEQESMYERYAALFALRNDSRDAAVSAIVAALGAKSALLKHEVAYVLGQLQNKAASDALS 242
Query: 482 KILRDLNEHPMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSG 303
+L++++EHPMVRHEAAEALGSIAD++SIALL+EF++DPEPIVSQSCEVALSMLE+E SG
Sbjct: 243 TVLKNVDEHPMVRHEAAEALGSIADQESIALLEEFAKDPEPIVSQSCEVALSMLEYERSG 302
Query: 302 KSFEFFFTQDPLVH*E 255
KSFEF F Q P V E
Sbjct: 303 KSFEFLFLQTPGVQQE 318
>sp|Q2QLW3|DOHH2_ORYSJ Deoxyhypusine hydroxylase-B OS=Oryza sativa subsp.
japonica GN=Os12g0626100 PE=2 SV=1
Length = 302
Score = 414 bits (1062), Expect = 1e-114
Identities = 218/307 (71%), Positives = 257/307 (83%), Gaps = 8/307 (2%)
Frame = -3
Query: 1169 LEKFLCERLLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHEAAFALGQM 990
+E FLC+RLLD +QPI+ERFRALFSLRNL+G APR AL+ A+RDSSNLLAHEAAFALGQM
Sbjct: 1 MEGFLCDRLLDAAQPIAERFRALFSLRNLRGDAPRRALLQAARDSSNLLAHEAAFALGQM 60
Query: 989 QDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCEL 810
QDAEA+PALE+VL D+SLHPIVRHEAAEALGAIGL + +L++SL +DPA EV+ETCEL
Sbjct: 61 QDAEAIPALEAVLKDLSLHPIVRHEAAEALGAIGLEKSISLLEESLAVDPAVEVQETCEL 120
Query: 809 ALKRIEELSSVDAEKN*S--DSTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYER 636
A++RIEE +KN S +S SPF+SVDPA PA V QLRE+L++E + MYER
Sbjct: 121 AIRRIEE------QKNTSGVESATVSPFLSVDPALPAKQGLPVEQLRELLLNEQESMYER 174
Query: 635 YAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALDTLSKILRDLNEH 456
YAALFALRN G+ AVSAIV +L SALLRHEVAYVLGQLQNKAA D LS +L++++EH
Sbjct: 175 YAALFALRNDSGDAAVSAIVAALGVKSALLRHEVAYVLGQLQNKAASDALSTVLKNVDEH 234
Query: 455 PMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGKSFEFFFTQ 276
PMVRHEAAEALGSIAD++SIALL+EF++DPEPIVSQSCEVALSMLE+E SGK+FEF F Q
Sbjct: 235 PMVRHEAAEALGSIADQESIALLEEFAKDPEPIVSQSCEVALSMLEYERSGKAFEFLFPQ 294
Query: 275 DPLVH*E 255
P V E
Sbjct: 295 TPQVQQE 301
>sp|Q5ZIP3|DOHH_CHICK Deoxyhypusine hydroxylase OS=Gallus gallus GN=DOHH PE=2
SV=1
Length = 299
Score = 260 bits (664), Expect = 2e-068
Identities = 145/286 (50%), Positives = 190/286 (66%), Gaps = 9/286 (3%)
Frame = -3
Query: 1145 LLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHEAAFALGQMQDAEAVPA 966
LLD +QP+ RFRALF+LRNL GPA + ++ DSS LL HE AF LGQM+D A+PA
Sbjct: 14 LLDAAQPLPARFRALFTLRNLGGPAAIDCIVRGFADSSALLKHELAFCLGQMRDRAAIPA 73
Query: 965 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKRIEEL 786
L VL D P+VRHEA EALGAIG ++L++ DP EV ETC+LA++R+E L
Sbjct: 74 LLGVLQDSQQEPMVRHEAGEALGAIGDPEVLDVLRR-YSEDPVVEVAETCQLAVRRLEWL 132
Query: 785 SSVDAEKN*SDSTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFALRNH 606
E SP+ SVDPA PA + V LR +L+DE++ +++RY A+FALRN
Sbjct: 133 QEHGEEPG------SSPYRSVDPAPPAEE-TDVATLRAVLLDESRPLFDRYRAMFALRNL 185
Query: 605 GGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALDTLSKILRDLNEHPMVRHEAAEA 426
GG +AV A+ D L A SAL RHE+ YVLGQ+Q++A + L+ LR E+PMVRHE AEA
Sbjct: 186 GGRDAVLALADGLRAGSALFRHEIGYVLGQMQDEACVPQLTAALRSRAENPMVRHECAEA 245
Query: 425 LGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGKSFEF 288
LGSIA + L+ F++D E +V +SCEVAL M E+EN G F++
Sbjct: 246 LGSIARPSCLETLRAFAQDEERVVRESCEVALDMYEYEN-GPQFQY 290
>sp|Q5PPJ4|DOHH_RAT Deoxyhypusine hydroxylase OS=Rattus norvegicus GN=Dohh PE=2
SV=1
Length = 302
Score = 260 bits (662), Expect = 3e-068
Identities = 146/288 (50%), Positives = 193/288 (67%), Gaps = 12/288 (4%)
Frame = -3
Query: 1145 LLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHEAAFALGQMQDAEAVPA 966
L+D +QP+ RFRALF+LR L GP + + DSS LL HE A+ LGQM+D A+P
Sbjct: 14 LVDSTQPLQARFRALFTLRGLGGPDAISWISRGFEDSSALLKHELAYCLGQMRDPRAIPV 73
Query: 965 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEI--LKKSLILDPAQEVRETCELALKRIE 792
L SVL D + P+VRHEA EALGAI GN ++ L K DP EV ETC+LA++R+E
Sbjct: 74 LVSVLQDRNQEPMVRHEAGEALGAI---GNPKVLGLLKQYSTDPVVEVAETCQLAVRRLE 130
Query: 791 ELSSVDAEKN*SDSTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFALR 612
L +++ ++T P++SVDPA PAA V +LRE L+DE + ++ERY A+FALR
Sbjct: 131 WL-----QQHPGEATCAGPYLSVDPAPPAAE-GDVGRLRETLLDEAQPLFERYRAMFALR 184
Query: 611 NHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALDTLSKILRDLNEHPMVRHEAA 432
N GG+EA A+ + L SAL RHEV YVLGQLQ++AA+ L+ L E PMVRHE A
Sbjct: 185 NVGGKEAALALAEGLKCGSALFRHEVGYVLGQLQHEAAVSELAATLARTTESPMVRHECA 244
Query: 431 EALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGKSFEF 288
EALG+IA +A L+E+ DPE +V +SCEVAL M E+EN G+ F++
Sbjct: 245 EALGAIARPACLAALREYITDPERVVRESCEVALDMYEYEN-GQDFQY 291
>sp|Q7ZUX6|DOHH_DANRE Deoxyhypusine hydroxylase OS=Danio rerio GN=dohh PE=2
SV=1
Length = 305
Score = 258 bits (657), Expect = 1e-067
Identities = 143/282 (50%), Positives = 189/282 (67%), Gaps = 4/282 (1%)
Frame = -3
Query: 1145 LLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHEAAFALGQMQDAEAVPA 966
L++ Q ++ RFRALF+LRNL G + A D S LL HE A+ LGQMQD A+P
Sbjct: 14 LVNTKQDLTTRFRALFTLRNLGGAEAVKWISEAFVDESALLKHELAYCLGQMQDESAIPT 73
Query: 965 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKRIEEL 786
LE+VL D + P+VRHEA EALGAIG E+LKK DP EV ETC+LA+KR+E L
Sbjct: 74 LEAVLKDTNQEPMVRHEAGEALGAIGNPKVLELLKK-YAEDPVIEVAETCQLAVKRLEWL 132
Query: 785 SSVDAEKN*SDSTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFALRNH 606
++ + D T+ +P+ SVDPA PA SV +LR L+DET +++RY A+FALRN
Sbjct: 133 --MNGGEQTKDGTDENPYCSVDPAPPAQR-KSVPELRTQLLDETLPLFDRYRAMFALRNL 189
Query: 605 GGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALDTLSKILRDLNEHPMVRHEAAEA 426
G EEAV A+ D L SAL RHE+ YVLGQ+Q++A++ L L ++E+ MVRHE AEA
Sbjct: 190 GTEEAVLALGDGLQCSSALFRHEIGYVLGQIQHEASIPQLQAALEKMDENAMVRHECAEA 249
Query: 425 LGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGK 300
LGSI E + +L+ + +D E +V +SCEVAL MLE+ENS +
Sbjct: 250 LGSIGKEPCVQILERYRKDQERVVKESCEVALDMLEYENSSQ 291
>sp|Q99LN9|DOHH_MOUSE Deoxyhypusine hydroxylase OS=Mus musculus GN=Dohh PE=2
SV=2
Length = 302
Score = 257 bits (655), Expect = 2e-067
Identities = 146/282 (51%), Positives = 186/282 (65%), Gaps = 11/282 (3%)
Frame = -3
Query: 1145 LLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHEAAFALGQMQDAEAVPA 966
L+D QP+ RFRALF+LR L GP + + DSS LL HE A+ LGQM+DA A+P
Sbjct: 14 LVDPKQPLQARFRALFTLRGLGGPDAISWISRGFEDSSALLKHELAYCLGQMRDARAIPV 73
Query: 965 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEI--LKKSLILDPAQEVRETCELALKRIE 792
L VL D S P+VRHEA EALGAI GN E+ L K DP EV ETC+LA+ R+E
Sbjct: 74 LADVLQDTSQEPMVRHEAGEALGAI---GNPEVLGLLKQYSTDPVVEVAETCQLAVGRLE 130
Query: 791 ELSSVDAEKN*SDSTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFALR 612
L +++ ++T P++SVDPA PAA V +LRE L+DE + ++ERY A+FALR
Sbjct: 131 WL-----QQHPGEATCAGPYLSVDPAPPAAE-QDVGRLREALLDEARPLFERYRAMFALR 184
Query: 611 NHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALDTLSKILRDLNEHPMVRHEAA 432
N GG+EA A+ + L SAL RHEV YVLGQLQ++AA+ L+ L E PMVRHE A
Sbjct: 185 NVGGKEAALALAEGLQCGSALFRHEVGYVLGQLQHEAAVPGLAATLARTTESPMVRHECA 244
Query: 431 EALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENS 306
EALG+IA +A L+E DPE +V +SCEVAL M E+E+S
Sbjct: 245 EALGAIARPACLAALREHIEDPEQVVRESCEVALDMYEYESS 286
>sp|Q9BU89|DOHH_HUMAN Deoxyhypusine hydroxylase OS=Homo sapiens GN=DOHH PE=1
SV=1
Length = 302
Score = 255 bits (649), Expect = 9e-067
Identities = 147/288 (51%), Positives = 186/288 (64%), Gaps = 9/288 (3%)
Frame = -3
Query: 1151 ERLLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHEAAFALGQMQDAEAV 972
+ L+D QP+ RFRALF+LR L GP + A D S LL HE A+ LGQMQDA A+
Sbjct: 12 QTLVDPKQPLQARFRALFTLRGLGGPGAIAWISQAFDDDSALLKHELAYCLGQMQDARAI 71
Query: 971 PALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKRIE 792
P L VL D P+VRHEA EALGAIG EILK+ DP EV ETC+LA++R+E
Sbjct: 72 PMLVDVLQDTRQEPMVRHEAGEALGAIGDPEVLEILKQ-YSSDPVIEVAETCQLAVRRLE 130
Query: 791 ELSSVDAEKN*SDSTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFALR 612
L E P++SVDPA PA V +LRE L+DE++ ++ERY A+FALR
Sbjct: 131 WLQQHGGE------PAAGPYLSVDPAPPAEE-RDVGRLREALLDESRPLFERYRAMFALR 183
Query: 611 NHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALDTLSKILRDLNEHPMVRHEAA 432
N GGEEA A+ + L SAL RHEV YVLGQLQ++AA+ L+ L E+PMVRHE A
Sbjct: 184 NAGGEEAALALAEGLHCGSALFRHEVGYVLGQLQHEAAVPQLAAALARCTENPMVRHECA 243
Query: 431 EALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGKSFEF 288
EALG+IA +A LQ + DPE +V +SCEVAL M E E +G++F++
Sbjct: 244 EALGAIARPACLAALQAHADDPERVVRESCEVALDMYEHE-TGRAFQY 290
>sp|Q0VC53|DOHH_BOVIN Deoxyhypusine hydroxylase OS=Bos taurus GN=DOHH PE=1 SV=1
Length = 303
Score = 252 bits (642), Expect = 6e-066
Identities = 141/288 (48%), Positives = 189/288 (65%), Gaps = 8/288 (2%)
Frame = -3
Query: 1151 ERLLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHEAAFALGQMQDAEAV 972
+ L+D QP+ RFRALF+LR L GP + + A D S LL HE A+ LGQMQD A+
Sbjct: 12 QTLVDPGQPLQARFRALFTLRGLGGPVAISWISRAFDDDSALLKHELAYCLGQMQDRRAI 71
Query: 971 PALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKRIE 792
P L VL D P+VRHEA EALGAIG EILK+ DP EV ETC+LA++R+E
Sbjct: 72 PVLLDVLRDTRQEPMVRHEAGEALGAIGDPEVLEILKQ-YSTDPVVEVAETCQLAVRRLE 130
Query: 791 ELSSVDAEKN*SDSTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFALR 612
L +++ +S R P++SVDPA PA + QLRE L+DE + +++RY A+FALR
Sbjct: 131 WL-----QQHGGESAVRGPYLSVDPAPPAEE-RDLGQLREALLDEARPLFDRYRAMFALR 184
Query: 611 NHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALDTLSKILRDLNEHPMVRHEAA 432
+ GG+EA A+ + L SAL RHE+ YVLGQ+Q++AA+ L+ L E+PMVRHE A
Sbjct: 185 DAGGKEAALALAEGLRCGSALFRHEIGYVLGQMQHEAAVPQLAAALAQPTENPMVRHECA 244
Query: 431 EALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGKSFEF 288
EALG+IA +A L+ DPE +V +SCEVAL M E+E +G +F++
Sbjct: 245 EALGAIARPACLAALRAHVADPERVVRESCEVALDMYEYE-TGSTFQY 291
>sp|Q66KT3|DOHH_XENLA Deoxyhypusine hydroxylase OS=Xenopus laevis GN=dohh PE=2
SV=1
Length = 303
Score = 249 bits (635), Expect = 4e-065
Identities = 144/285 (50%), Positives = 184/285 (64%), Gaps = 8/285 (2%)
Frame = -3
Query: 1157 LCERLLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHEAAFALGQMQDAE 978
L + L+D +P+ RFRALF+LRNL G + + +D S LL HE A+ LGQM+D
Sbjct: 12 LGQLLIDPGKPLPLRFRALFTLRNLGGAEAIDCIGRGFQDESALLKHELAYCLGQMKDRR 71
Query: 977 AVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKR 798
A+P L+ VL D P+VRHEA EALGAIG E+L++ DP EV ETC+LA+ R
Sbjct: 72 ALPVLKQVLQDRQQEPMVRHEAGEALGAIGDPEVLELLRE-YAQDPVIEVAETCQLAVSR 130
Query: 797 IEELSSVDAEKN*SDSTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFA 618
IE L +KN DS + +P++SVDPA PA V LR L+DET ++ RY A+FA
Sbjct: 131 IEWL-----QKN-PDSPDTNPYLSVDPAPPAEE-KDVPTLRATLLDETCPLFHRYRAMFA 183
Query: 617 LRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALDTLSKILRDLNEHPMVRHE 438
LRN GGEEAV A+ D L +L RHE+ YVLGQ+Q+KAA+ LS L E+PMVRHE
Sbjct: 184 LRNIGGEEAVLALADGLQIGGSLFRHEIGYVLGQMQHKAAVPGLSAALERFEENPMVRHE 243
Query: 437 AAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSG 303
AEALGSIA E + L+ D E +V +SCEVAL M ++ENSG
Sbjct: 244 CAEALGSIAHEDCLKALRAHVGDGERVVRESCEVALDMHDYENSG 288
Score = 121 bits (302), Expect = 1e-026
Identities = 59/131 (45%), Positives = 92/131 (70%)
Frame = -3
Query: 707 AAAFSSVHQLREILMDETKGMYERYAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAY 528
A+ S VH L ++L+D K + R+ ALF LRN GG EA+ I +SALL+HE+AY
Sbjct: 3 ASLSSEVHSLGQLLIDPGKPLPLRFRALFTLRNLGGAEAIDCIGRGFQDESALLKHELAY 62
Query: 527 VLGQLQNKAALDTLSKILRDLNEHPMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQ 348
LGQ++++ AL L ++L+D + PMVRHEA EALG+I D + + LL+E+++DP V++
Sbjct: 63 CLGQMKDRRALPVLKQVLQDRQQEPMVRHEAGEALGAIGDPEVLELLREYAQDPVIEVAE 122
Query: 347 SCEVALSMLEF 315
+C++A+S +E+
Sbjct: 123 TCQLAVSRIEW 133
>sp|Q9V9U4|DOHH_DROME Deoxyhypusine hydroxylase OS=Drosophila melanogaster
GN=nero PE=2 SV=1
Length = 302
Score = 230 bits (586), Expect = 2e-059
Identities = 130/280 (46%), Positives = 177/280 (63%), Gaps = 7/280 (2%)
Frame = -3
Query: 1145 LLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHEAAFALGQMQDAEAVPA 966
L ++ +P+ ERFRALF+L+N+ G A A+ A D S LL HE A+ LGQMQDA+A+
Sbjct: 14 LNNKERPLKERFRALFTLKNIGGGAAIEAISKAFDDDSALLKHELAYCLGQMQDAQALDI 73
Query: 965 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKRIEEL 786
L VL D + P+VRHEAAEA+GAIG IL++ DP EV ETC +AL R+ L
Sbjct: 74 LTKVLKDTTQEPMVRHEAAEAMGAIGHPDVLPILEE-YKQDPVVEVAETCAIALDRVRWL 132
Query: 785 SSVDAEKN*SDSTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFALRNH 606
S + +P+ SVDP+ P A SV +L+ I +D + +++RY A+F+LRN
Sbjct: 133 QSG------QKVDDSNPYASVDPSPPTAGDKSVTELKAIYLDAQQSLFDRYRAMFSLRNL 186
Query: 605 GGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALDTLSKILRDLNEHPMVRHEAAEA 426
EE+V AI + L SAL RHEVA+VLGQLQ ++ L + L D E+ MVRHE AEA
Sbjct: 187 RTEESVLAIAEGLKDSSALFRHEVAFVLGQLQEPCSIPFLQENLEDRLENEMVRHECAEA 246
Query: 425 LGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENS 306
LG+IA E I +L ++ D + +V +SC +AL M E+ENS
Sbjct: 247 LGAIATEDCIQILNRYAEDDKRVVKESCVIALDMCEYENS 286
>sp|Q297S2|DOHH_DROPS Deoxyhypusine hydroxylase OS=Drosophila pseudoobscura
pseudoobscura GN=nero PE=3 SV=1
Length = 302
Score = 227 bits (577), Expect = 2e-058
Identities = 128/280 (45%), Positives = 176/280 (62%), Gaps = 7/280 (2%)
Frame = -3
Query: 1145 LLDQSQPISERFRALFSLRNLKGPAPRNALILASRDSSNLLAHEAAFALGQMQDAEAVPA 966
L ++ +P+ ERFRALF+L+N+ G +A+ A D S LL HE A+ LGQMQD A+
Sbjct: 14 LNNKDRPLKERFRALFTLKNIGGKTAIDAISKAFDDDSALLKHELAYCLGQMQDPTALEI 73
Query: 965 LESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKRIEEL 786
L VL D + P+VRHEAAEA+GAIG A IL++ DP EV ETC +AL R+ L
Sbjct: 74 LTKVLKDTTQEPMVRHEAAEAMGAIGHADVLAILEE-YKKDPVVEVAETCAIALDRVRWL 132
Query: 785 SSVDAEKN*SDSTERSPFMSVDPAAPAAAFSSVHQLREILMDETKGMYERYAALFALRNH 606
S + +P+ SVDP+ P A SV +L+ I +D + +++RY A+F+LRN
Sbjct: 133 QSG------QQVADNNPYASVDPSPPTAGDKSVAELKAIYLDAKQTLFDRYRAMFSLRNL 186
Query: 605 GGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALDTLSKILRDLNEHPMVRHEAAEA 426
EE+V AI + L SAL RHEVA+VLGQLQ ++ L + L D E+ MVRHE AEA
Sbjct: 187 CTEESVLAIAEGLKDSSALFRHEVAFVLGQLQEPCSIPYLQENLEDHKENEMVRHECAEA 246
Query: 425 LGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENS 306
LG+IA + I +L ++ D + +V +SC +AL M E+ENS
Sbjct: 247 LGAIATDDCIQILTRYADDEKRVVKESCVIALDMCEYENS 286
Score = 118 bits (295), Expect = 1e-025
Identities = 55/124 (44%), Positives = 88/124 (70%)
Frame = -3
Query: 671 ILMDETKGMYERYAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALD 492
+L ++ + + ER+ ALF L+N GG+ A+ AI + DSALL+HE+AY LGQ+Q+ AL+
Sbjct: 13 VLNNKDRPLKERFRALFTLKNIGGKTAIDAISKAFDDDSALLKHELAYCLGQMQDPTALE 72
Query: 491 TLSKILRDLNEHPMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFE 312
L+K+L+D + PMVRHEAAEA+G+I +A+L+E+ +DP V+++C +AL + +
Sbjct: 73 ILTKVLKDTTQEPMVRHEAAEAMGAIGHADVLAILEEYKKDPVVEVAETCAIALDRVRWL 132
Query: 311 NSGK 300
SG+
Sbjct: 133 QSGQ 136
>sp|Q9P6K9|DOHH_SCHPO Deoxyhypusine hydroxylase OS=Schizosaccharomyces pombe
GN=lia1 PE=2 SV=1
Length = 318
Score = 216 bits (550), Expect = 3e-055
Identities = 129/309 (41%), Positives = 183/309 (59%), Gaps = 12/309 (3%)
Frame = -3
Query: 1205 SASPTEDGGVSKLEKFLCERLLDQSQPISERFRALFSLRNLKGPAPR---NALILASRDS 1035
S+ P + +LE+ L LD+S P+S R+RALFSL L + +A+ A D
Sbjct: 2 SSEPVPQAVIDELERVLVN--LDKSNPLSFRYRALFSLNALAKKGDKRAVDAIYKAFIDD 59
Query: 1034 SNLLAHEAAFALGQMQDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKS 855
S LL HE A+ +GQ AV L +++ND+ +VRHEAAEALGA+G + +L+K
Sbjct: 60 SELLKHEMAYVMGQSGQQYAVQPLINIVNDLDQQVMVRHEAAEALGALGFTESLPVLEKY 119
Query: 854 LILDPAQEVRETCELALKRIEELSSVDAEKN*SDSTERSPFMSVDPAAPAA-----AFSS 690
DP +RETCELA+ RI+ + +D KN T VDPA P S
Sbjct: 120 YKEDPLAPIRETCELAIARIQWKNGLD--KNNEKITPSMYDSVVDPAPPMPDHEQDVKSE 177
Query: 689 VHQLREILMDETKGMYERYAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQ 510
V +LR ++D+ ++ RY +F LRN G EEAV A+ D S L RHE+A+V GQ+
Sbjct: 178 VAKLRSEIVDQNLPLFYRYRVMFRLRNIGNEEAVLALTDGFKDPSPLFRHEIAFVFGQMI 237
Query: 509 NKAALDTLSKILRDLNEHPMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVAL 330
A++ L K+L + E PMVRHEAAEALG IA+++ + +L++FS+D +V++SC VAL
Sbjct: 238 APASVPALIKVLENTEEVPMVRHEAAEALGGIANDECLPVLKKFSKDDVRVVAESCIVAL 297
Query: 329 SMLEFENSG 303
M+E+E SG
Sbjct: 298 DMIEYEKSG 306
>sp|Q6CHJ7|DOHH_YARLI Deoxyhypusine hydroxylase OS=Yarrowia lipolytica GN=LIA1
PE=3 SV=1
Length = 308
Score = 211 bits (536), Expect = 1e-053
Identities = 119/290 (41%), Positives = 184/290 (63%), Gaps = 13/290 (4%)
Frame = -3
Query: 1139 DQSQPISERFRALFSLRNLKGPAPRNALILAS---RDSSNLLAHEAAFALGQMQDAEAVP 969
D ++ RFRALFSL+++ A+ + + +D S LL HE A+ LGQ ++ AV
Sbjct: 17 DGQTALALRFRALFSLKDMGEKGDNGAIDVIAEGFKDDSELLKHELAYVLGQTKNFHAVK 76
Query: 968 ALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILKKSLILDPAQEVRETCELALKRIEE 789
L+ VL D + +VRHEAAEALGA+G G+ +L++ DP + +RETCELAL+RI+
Sbjct: 77 PLQGVLADTNQQAMVRHEAAEALGALGDKGSVAMLQEYFENDPLEVIRETCELALERIKW 136
Query: 788 LSSVDAEKN*SDSTERSPFMSVDPAAP-------AAAFSSVHQLREILMDETKGMYERYA 630
+S A+ +++ ++S + S+DPA P + ++V +L++ LMD+++ ++ RY
Sbjct: 137 ENSEAAK---TETLQKSAYTSIDPAPPLPTDQAEGSDKATVEKLQKTLMDKSQSLFHRYR 193
Query: 629 ALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQNKAALDTLSKILRDLNEHPM 450
A+F LR+ G E+AV A+ SAL RHE+AYV GQ+ + A++ L K+L E M
Sbjct: 194 AMFRLRDIGTEDAVLALATGFDDSSALFRHEIAYVFGQMSDPASVPALIKVLGKTEEEGM 253
Query: 449 VRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALSMLEFENSGK 300
VRHEAAEALGSIA + + +L++F+ D + +V +S VAL M E+ENS +
Sbjct: 254 VRHEAAEALGSIATDDVLPILKKFAEDKDQVVRESAIVALDMYEYENSNE 303
>sp|Q59Z14|DOHH_CANAL Deoxyhypusine hydroxylase OS=Candida albicans GN=LIA1 PE=3
SV=1
Length = 318
Score = 208 bits (528), Expect = 9e-053
Identities = 117/250 (46%), Positives = 161/250 (64%), Gaps = 6/250 (2%)
Frame = -3
Query: 1040 DSSNLLAHEAAFALGQMQDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILK 861
D S LL HE A+ LGQ +D A P L VL + + +VRHEAAEALGA+G + +L+
Sbjct: 65 DDSELLKHEVAYVLGQTKDLYAAPYLREVLENDNQQCMVRHEAAEALGALGDKESLPLLE 124
Query: 860 KSLILDPAQEVRETCELALKRIEELSSVDAEKN*SDSTERSPFMSVDPAAPAA---AFSS 690
K DP E+R+TCELA++RI +S EK ++ E+S + S+DPA P A + S
Sbjct: 125 KYFKEDPLLEIRQTCELAIERIHWENS---EKAKNEVLEKSLYTSIDPAPPLATNDSTSK 181
Query: 689 VHQLREILMDETKGMYERYAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQ 510
V +L+EIL D+ K ++ERY A+F LR+ G +EA A+ SAL +HE+AYV GQ+
Sbjct: 182 VEKLKEILNDQDKPLFERYRAMFRLRDIGTDEACLALASGFDDPSALFKHEIAYVFGQMC 241
Query: 509 NKAALDTLSKILRDLNEHPMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVAL 330
N + +L K+L+D +E MVRHEAAEALGSIA ++ + +LQ F D EP+V S VAL
Sbjct: 242 NPVTVPSLIKVLKDESEAGMVRHEAAEALGSIATDECLPVLQSFLNDSEPVVRDSAIVAL 301
Query: 329 SMLEFENSGK 300
M E+ENS +
Sbjct: 302 DMYEYENSNE 311
>sp|Q6FUV3|DOHH_CANGA Deoxyhypusine hydroxylase OS=Candida glabrata GN=LIA1 PE=3
SV=1
Length = 322
Score = 198 bits (502), Expect = 1e-049
Identities = 110/249 (44%), Positives = 161/249 (64%), Gaps = 5/249 (2%)
Frame = -3
Query: 1040 DSSNLLAHEAAFALGQMQDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILK 861
D+S LL HE A+ LGQ ++ +A P L + D++ P+VRHEAAEALGA+G + E L+
Sbjct: 71 DNSELLKHEVAYVLGQTKNLKAAPLLRKTMLDLAQQPMVRHEAAEALGALGDKDSLEDLE 130
Query: 860 KSLILDPAQEVRETCELALKRIEELSSVDAEKN*SDSTERSPFMSVDPAAPAAAFS--SV 687
K L DP VRETCELA+ RI S K +S ++S + S+DPA P A +
Sbjct: 131 KCLKNDPHVAVRETCELAIARINWQHSDAPTK---ESLQQSLYSSIDPAPPLALEKEYDL 187
Query: 686 HQLREILMDETKGMYERYAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQN 507
+L+++L D+ K ++ RY A+F LR+ G +EAV A+ + SAL +HE+AYV GQ+ +
Sbjct: 188 EELKKLLNDQEKPLFLRYRAMFRLRDIGTDEAVLALASGFNDPSALFKHEIAYVFGQMGS 247
Query: 506 KAALDTLSKILRDLNEHPMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALS 327
AA+ +L+++L E PMVRHEAAEALG+IA E ++ +L+++ D +V +S VAL
Sbjct: 248 TAAVPSLTEVLGRKEEAPMVRHEAAEALGAIASEDALPILKQYLNDEVDVVRESAIVALD 307
Query: 326 MLEFENSGK 300
M E+ENS +
Sbjct: 308 MWEYENSNE 316
>sp|P47120|DOHH_YEAST Deoxyhypusine hydroxylase OS=Saccharomyces cerevisiae
GN=LIA1 PE=1 SV=1
Length = 325
Score = 193 bits (488), Expect = 4e-048
Identities = 104/249 (41%), Positives = 159/249 (63%), Gaps = 5/249 (2%)
Frame = -3
Query: 1040 DSSNLLAHEAAFALGQMQDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILK 861
D S LL HE A+ LGQ ++ +A P L V+ D + P+VRHEAAEALGA+G + + L
Sbjct: 72 DKSELLKHEVAYVLGQTKNLDAAPTLRHVMLDQNQEPMVRHEAAEALGALGDKDSLDDLN 131
Query: 860 KSLILDPAQEVRETCELALKRIEELSSVDAEKN*SDSTERSPFMSVDPA--APAAAFSSV 687
K+ DP VRETCELA+ RI +K ++ ++S + S+DPA P +++
Sbjct: 132 KAAKEDPHVAVRETCELAINRINWTHGGAKDK---ENLQQSLYSSIDPAPPLPLEKDATI 188
Query: 686 HQLREILMDETKGMYERYAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQN 507
+L+ +L D + +++RY A+F LR+ G +EA+ A+ SA+S+L +HE+AYV GQ+ +
Sbjct: 189 PELQALLNDPKQPLFQRYRAMFRLRDIGTDEAILALATGFSAESSLFKHEIAYVFGQIGS 248
Query: 506 KAALDTLSKILRDLNEHPMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALS 327
AA+ +L ++L E PMVRHEAAEALG+IA + + +L+ + D +V +SC VAL
Sbjct: 249 PAAVPSLIEVLGRKEEAPMVRHEAAEALGAIASPEVVDVLKSYLNDEVDVVRESCIVALD 308
Query: 326 MLEFENSGK 300
M ++ENS +
Sbjct: 309 MYDYENSNE 317
>sp|Q6CV81|DOHH_KLULA Deoxyhypusine hydroxylase OS=Kluyveromyces lactis GN=LIA1
PE=3 SV=1
Length = 322
Score = 190 bits (480), Expect = 3e-047
Identities = 104/247 (42%), Positives = 152/247 (61%), Gaps = 5/247 (2%)
Frame = -3
Query: 1040 DSSNLLAHEAAFALGQMQDAEAVPALESVLNDMSLHPIVRHEAAEALGAIGLAGNAEILK 861
D S LL HE A+ LGQ ++ P L VL D +VRHEAAEALGA+ + +IL+
Sbjct: 71 DESELLKHEVAYVLGQTKNMAGAPLLRDVLADDKQQCMVRHEAAEALGALNDVDSLDILE 130
Query: 860 KSLILDPAQEVRETCELALKRIEELSSVDAEKN*SDSTERSPFMSVDPAAPAAAFS--SV 687
K DP E+R+TCELA+ RI+ +S + + ++ + S + S+DPA P + +
Sbjct: 131 KYFKEDPLLEIRQTCELAIDRIKWETSEEGRR---EALQESLYSSIDPAPPFSLEKDYKI 187
Query: 686 HQLREILMDETKGMYERYAALFALRNHGGEEAVSAIVDSLSADSALLRHEVAYVLGQLQN 507
+L++IL D+ + ++ERY A+F LR+ G +EA A+ SAL +HE+AYV GQ+ N
Sbjct: 188 QELKDILNDQNRPLFERYRAMFRLRDIGNDEACLALASGFDDPSALFKHEIAYVFGQICN 247
Query: 506 KAALDTLSKILRDLNEHPMVRHEAAEALGSIADEQSIALLQEFSRDPEPIVSQSCEVALS 327
+ L ++L E PMVRHEAAEALGSIA + + +L+E +D + +V +S VAL
Sbjct: 248 PVVVPHLKEVLARPEEAPMVRHEAAEALGSIATDDVLPVLKEHLKDSDSVVRESAIVALD 307
Query: 326 MLEFENS 306
M E+ENS
Sbjct: 308 MYEYENS 314
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 159,249,259,203
Number of Sequences: 518415
Number of Extensions: 159249259203
Number of Successful Extensions: 968868021
Number of sequences better than 0.0: 0
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