BLASTX 7.6.2
Query= UN41159 /QuerySize=1994
(1993 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9LPD2|GENL1_ARATH Flap endonuclease GEN-like 1 OS=Arabidopsi... 919 1e-266
sp|Q64MA3|GENL1_ORYSJ Flap endonuclease GEN-like 1 OS=Oryza sati... 500 3e-140
sp|Q8BMI4|GEN_MOUSE Flap endonuclease GEN homolog 1 OS=Mus muscu... 152 1e-035
sp|Q17RS7|GEN_HUMAN Flap endonuclease GEN homolog 1 OS=Homo sapi... 150 4e-035
sp|Q29FC1|GEN_DROPS Flap endonuclease GEN OS=Drosophila pseudoob... 134 4e-030
sp|Q9VRJ0|GEN_DROME Flap endonuclease GEN OS=Drosophila melanoga... 132 8e-030
sp|Q8W5R1|GENL2_ORYSJ Flap endonuclease GEN-like 2 OS=Oryza sati... 121 3e-026
sp|Q9ATY5|UVH3_ARATH DNA repair protein UVH3 OS=Arabidopsis thal... 108 2e-022
sp|Q9M2Z3|GENL2_ARATH Flap endonuclease GEN-like 2 OS=Arabidopsi... 96 7e-019
sp|A6UX46|FEN_META3 Flap structure-specific endonuclease OS=Meth... 83 8e-015
sp|P28706|RAD13_SCHPO DNA repair protein rad13 OS=Schizosaccharo... 74 3e-012
sp|P07276|RAD2_YEAST DNA repair protein RAD2 OS=Saccharomyces ce... 72 1e-011
sp|P35689|ERCC5_MOUSE DNA repair protein complementing XP-G cell... 70 4e-011
>sp|Q9LPD2|GENL1_ARATH Flap endonuclease GEN-like 1 OS=Arabidopsis thaliana
GN=GEN1 PE=2 SV=2
Length = 599
Score = 919 bits (2375), Expect = 1e-266
Identities = 470/614 (76%), Positives = 516/614 (84%), Gaps = 30/614 (4%)
Frame = +2
Query: 86 MGVGGKFWDLVRPYGRNEGSDYLREKRVAVDLSFWIIQHETAVKGFALKPHLRLTFFRTI 265
MGVGG FWDL+RPY + +G D+LR KRVAVDLSFWI+QHETAVKGF LKPHLRLTFFRTI
Sbjct: 1 MGVGGNFWDLLRPYAQQQGFDFLRNKRVAVDLSFWIVQHETAVKGFVLKPHLRLTFFRTI 60
Query: 266 NLFSKFGAYPVFVVDGTPSPLKSHTRISRFYRSSGIDTSSLQ--EGVVSVERNKQFCEWV 439
NLFSKFGAYPVFVVDGTPSPLKS RISRF+RSSGIDT +L + VSVERNK F EWV
Sbjct: 61 NLFSKFGAYPVFVVDGTPSPLKSQARISRFFRSSGIDTCNLPVIKDGVSVERNKLFSEWV 120
Query: 440 TECVELLKLLGIPVLKANGEAEALCAQLNSHGFVDACITPDSDAFLFGASSVIKSIKPNS 619
ECVELL+LLGIPVLKANGEAEALCAQLNS GFVDACITPDSDAFLFGA VIK IKPNS
Sbjct: 121 RECVELLELLGIPVLKANGEAEALCAQLNSQGFVDACITPDSDAFLFGAMCVIKDIKPNS 180
Query: 620 TEPFECYHMSDIEAGLGLKRRHLIAISLLVGNDFDSGGVSGIGLDKALRIVRAFSEDDIL 799
EPFECYHMS IE+GLGLKR+HLIAISLLVGND+DSGGV GIG+DKALRIVR FSED +L
Sbjct: 181 REPFECYHMSHIESGLGLKRKHLIAISLLVGNDYDSGGVLGIGVDKALRIVREFSEDQVL 240
Query: 800 QRLEDIGKGFKPAVSGGTKSVDVDDDDDGVESSSQMKRRLPHCSRCGHPGSKRSHFKSSC 979
+RL+DIG G +PAV GG KS DDG E S+MK+R PHCSRCGH GSKR+HFKSSC
Sbjct: 241 ERLQDIGNGLQPAVPGGIKS-----GDDGEEFRSEMKKRSPHCSRCGHLGSKRTHFKSSC 295
Query: 980 EHCSSDSGCIKKPLEFTCECSFCTKDRELKEQKKTENWWIKVCDRIALGPDFPNRKIIQL 1159
EHC DSGCIKKPL F CECSFC+KDR+L+EQKKT +WWIKVCD+IAL P+FPNRKII+L
Sbjct: 296 EHCGCDSGCIKKPLGFRCECSFCSKDRDLREQKKTNDWWIKVCDKIALAPEFPNRKIIEL 355
Query: 1160 YLSDS-FTEDGSSMSWGTPDTEMLVDCLVFNLHWDPCYVRKMLLPMLSTIYLREKARSSN 1336
YLSD T DGSSMSWGTPDT MLVD +VF LHWDP YVRKMLLPMLSTIYLREKAR +N
Sbjct: 356 YLSDGLMTGDGSSMSWGTPDTGMLVDLMVFKLHWDPSYVRKMLLPMLSTIYLREKAR-NN 414
Query: 1337 TGNPLLCDQYEFHSIKCMKTRYGHKSFVIRWRKPRSTSGLT-----PEKPIVVWEDEEEV 1501
TG LLCDQYEFHSIKC+KTRYGH+SFVIRWRKP+STSG + PE+ IVV E+EEE
Sbjct: 415 TGYALLCDQYEFHSIKCIKTRYGHQSFVIRWRKPKSTSGYSHSHNEPEESIVVLEEEEES 474
Query: 1502 VEEEECVGLLDGLNEPQVQDDNGECFLLTDECVGLVQSAFPEETEHFLKEKKLRESKKKN 1681
V+ LDGLNEPQVQ+DNG+CFLLTDEC+GLVQSAFP+ETEHFL EKKLRESKKKN
Sbjct: 475 VDP------LDGLNEPQVQNDNGDCFLLTDECIGLVQSAFPDETEHFLHEKKLRESKKKN 528
Query: 1682 VCEGAA----SSSVGAQRSITDFYRSTKAAATPAQSVDTGGSSIAFASVEKKRQATSGSF 1849
V E ++++G QRSITDFYRS K AA QS++TGGSS AS EKKRQATS S
Sbjct: 529 VSEEETATPRATTMGVQRSITDFYRSAKKAAA-GQSIETGGSS--KASAEKKRQATSTSS 585
Query: 1850 S---KSVRRRLLFG 1882
S KSVRRRLLFG
Sbjct: 586 SNLTKSVRRRLLFG 599
>sp|Q64MA3|GENL1_ORYSJ Flap endonuclease GEN-like 1 OS=Oryza sativa subsp.
japonica GN=RAD PE=2 SV=1
Length = 629
Score = 500 bits (1285), Expect = 3e-140
Identities = 256/511 (50%), Positives = 349/511 (68%), Gaps = 26/511 (5%)
Frame = +2
Query: 86 MGVGGKFWDLVRPYGRNEGSDYLREKRVAVDLSFWIIQHETAVKG---FALKPHLRLTFF 256
MGVGG FWDL++PY R+EG+ YLR +RVAVDLSFW++ H A++ A PHLR FF
Sbjct: 1 MGVGGSFWDLLKPYARHEGAGYLRGRRVAVDLSFWVVSHSAAIRARSPHARLPHLRTLFF 60
Query: 257 RTINLFSKFGAYPVFVVDGTPSPLKSHTRISRFYRSSGIDTSSL--QEGVVSVE-----R 415
RT++LFSK GA+PVFVVDG PSPLKS R +RF+R SG+D ++L E S + R
Sbjct: 61 RTLSLFSKMGAFPVFVVDGQPSPLKSQVRAARFFRGSGMDLAALPSTEAEASADALVQPR 120
Query: 416 NKQFCEWVTECVELLKLLGIPVLKANGEAEALCAQLNSHGFVDACITPDSDAFLFGASSV 595
N +F +V +CVELL+ LG+PVL+A GE EALCAQLN+ G VDACIT DSDAFLFGA +V
Sbjct: 121 NAKFTRYVEDCVELLEYLGMPVLRAKGEGEALCAQLNNQGHVDACITSDSDAFLFGAKTV 180
Query: 596 IKSIKPNSTEPFECYHMSDIEAGLGLKRRHLIAISLLVGNDFDSGGVSGIGLDKALRIVR 775
IK ++ N EPFECY+M+DIE+GLGLKR+ ++A++LLVG+D D GV G G + ALR V+
Sbjct: 181 IKVLRSNCKEPFECYNMADIESGLGLKRKQMVAMALLVGSDHDLHGVPGFGPETALRFVQ 240
Query: 776 AFSEDDILQRLEDIGKGFKPAVSGGTKSVDVDDDDDGVESSSQMKRRLPHCSRCGHPGSK 955
F ED++L +L +IGKG P + ++ DD + S + R PHCS CGHPG+K
Sbjct: 241 LFDEDNVLAKLYEIGKGVYPFIGVSAPNI---DDLPSPSTKSLPRARSPHCSHCGHPGNK 297
Query: 956 RSHFKSSCEHCSSDS--GCIKKPLEFTCECSFCTKDRELKEQKKTENWWIKVCDRIALGP 1129
++H K C C DS C++KP F CEC C K R+LK Q++ ENW IKVC RIA
Sbjct: 298 KNHIKDGCNFCLVDSLENCVEKPAGFICECPSCDKARDLKVQRRNENWQIKVCKRIAAET 357
Query: 1130 DFPNRKIIQLYLSDSFTEDGSS---MSWGTPDTEMLVDCLVFNLHWDPCYVRKMLLPMLS 1300
+FPN +II LYL+D ++ + ++W PD E+LVD L F +W+P Y+R+ +LPMLS
Sbjct: 358 NFPNEEIINLYLNDDNLDNENGVPLLTWNKPDMEILVDFLSFKQNWEPAYIRQRMLPMLS 417
Query: 1301 TIYLREKARSSNTGNPLLCDQYEFHSIKCMKTRYGHKSFVIRWRKPRSTSGLTPEKPIVV 1480
TIYLRE A SS + + LL DQY+FHSI+ +K RYGH ++++W++ + S ++ + P
Sbjct: 418 TIYLREMA-SSQSKSFLLYDQYKFHSIQRIKIRYGHPYYLVKWKRV-TRSMISNDPP--- 472
Query: 1481 WEDEEEVVEEEECVGLLDGLNEPQVQDDNGE 1573
+ E+ + + V +LDG + +V D+ E
Sbjct: 473 -SKQTELEGKNDKVEVLDG--DDEVVDEEEE 500
Score = 68 bits (165), Expect = 2e-010
Identities = 50/139 (35%), Positives = 70/139 (50%), Gaps = 8/139 (5%)
Frame = +2
Query: 1475 VVWEDEEEVVEEEECVGLLDGLNEPQVQDDNGECFLLTDECVGLVQSAFPEETEHFLKEK 1654
VV E+EEE E LLD + PQV DD+ +CFLLTDE + LV +AFP+E + F +E+
Sbjct: 494 VVDEEEEEPTMISETTELLDEPDVPQVLDDDKDCFLLTDEDIELVNAAFPDEAQRFQEEQ 553
Query: 1655 KLRESK----KKNVCEGAASSSVGAQRSITDFYRSTKAAATPAQSVDTGGSSIAFASVEK 1822
+L+E+K K + + G + S + S D+G S +
Sbjct: 554 RLKEAKSIARKSKLNVAGFETPKGPRPSGVQLSIKEFYRSKKGLSGDSGKD----GSRKS 609
Query: 1823 KRQATSGSFSKSVRRRLLF 1879
S + KSVRRRLLF
Sbjct: 610 SDVDLSKNLPKSVRRRLLF 628
>sp|Q8BMI4|GEN_MOUSE Flap endonuclease GEN homolog 1 OS=Mus musculus GN=Gen1
PE=2 SV=2
Length = 908
Score = 152 bits (382), Expect = 1e-035
Identities = 87/236 (36%), Positives = 136/236 (57%), Gaps = 8/236 (3%)
Frame = +2
Query: 107 WDLVRPYGRNEGSDYLREKRVAVDLSFWIIQHETAVK--GFALKPHLRLTFFRTINLFSK 280
W ++ P ++ L K +AVDLS W+ + +T K G KPHLR FFR I+ ++
Sbjct: 7 WQILEPVKQHIHLQDLSGKTIAVDLSLWVCEAQTVKKMIGTVKKPHLRNLFFR-ISYLTQ 65
Query: 281 FGAYPVFVVDGTPSPLKSHTRISRFYRSSGIDTSSLQEGVVSVERNKQFCEWVTECVELL 460
VFV++G P LK+ R G S + F + EC+E+L
Sbjct: 66 MNVKLVFVMEGEPPMLKADVISKRTQTRYGPSGKSRSQKT----GRSHFKSVLRECLEML 121
Query: 461 KLLGIPVLKANGEAEALCAQLNSHGFVDACITPDSDAFLFGASSVIKSIKPNSTEP-FEC 637
+ LG+P ++A GEAEA+CA LN+ G VD C+T D DAFL+GA +V ++ N+ +P +C
Sbjct: 122 ECLGMPWVQAAGEAEAMCAYLNASGHVDGCLTNDGDAFLYGAQTVYRNFTMNTKDPHVDC 181
Query: 638 YHMSDIEAGLGLKRRHLIAISLLVGNDFDSGGVSGIGLDKALRIVRAFSEDDILQR 805
Y +S I++ LGL R L+ +++L+G D+ GV G+G ++AL++++ F +LQR
Sbjct: 182 YTISSIKSKLGLDRDALVGLAVLLGCDYLPKGVPGVGKEQALKLLQIFKGQSLLQR 237
>sp|Q17RS7|GEN_HUMAN Flap endonuclease GEN homolog 1 OS=Homo sapiens GN=GEN1
PE=2 SV=2
Length = 908
Score = 150 bits (378), Expect = 4e-035
Identities = 89/239 (37%), Positives = 136/239 (56%), Gaps = 14/239 (5%)
Frame = +2
Query: 107 WDLVRPYGRNEGSDYLREKRVAVDLSFWIIQHETAVK--GFALKPHLRLTFFRTINLFSK 280
W ++ P ++ L K +AVDLS W+ + +T K G +KPHLR FFR I+ ++
Sbjct: 7 WQILEPVKQHIPLRNLGGKTIAVDLSLWVCEAQTVKKMMGSVMKPHLRNLFFR-ISYLTQ 65
Query: 281 FGAYPVFVVDGTPSPLKSHT---RISRFYRSSGIDTSSLQEGVVSVERNKQFCEWVTECV 451
VFV++G P LK+ R Y SSG S F + EC+
Sbjct: 66 MDVKLVFVMEGEPPKLKADVISKRNQSRYGSSGKSWS-------QKTGRSHFKSVLRECL 118
Query: 452 ELLKLLGIPVLKANGEAEALCAQLNSHGFVDACITPDSDAFLFGASSVIKSIKPNSTEP- 628
+L+ LGIP ++A GEAEA+CA LN+ G VD C+T D D FL+GA +V ++ N+ +P
Sbjct: 119 HMLECLGIPWVQAAGEAEAMCAYLNAGGHVDGCLTNDGDTFLYGAQTVYRNFTMNTKDPH 178
Query: 629 FECYHMSDIEAGLGLKRRHLIAISLLVGNDFDSGGVSGIGLDKALRIVRAFSEDDILQR 805
+CY MS I++ LGL R L+ +++L+G D+ GV G+G ++AL++++ +LQR
Sbjct: 179 VDCYTMSSIKSKLGLDRDALVGLAILLGCDYLPKGVPGVGKEQALKLIQILKGQSLLQR 237
Score = 59 bits (142), Expect = 9e-008
Identities = 42/163 (25%), Positives = 70/163 (42%), Gaps = 11/163 (6%)
Frame = +2
Query: 875 DDDGVESSSQM--KRRLPHCSRCGHPGSKRSHFKSSCEHCSSDSGCIKKPLEFTCECSF- 1045
++ SS Q+ ++L HCS C HPGS + H ++ C C SD C E+ C C +
Sbjct: 242 NETSCNSSPQLLVTKKLAHCSVCSHPGSPKDHERNGCRLCKSDKYCEPHDYEYCCPCEWH 301
Query: 1046 -CTKDRELKEQKKTENWWIKVCDRIALGPDFPNRKIIQLYLSDSFTEDGSSMSWGTPDTE 1222
DR+L E + C+ FP ++IQ +L + + + + PD
Sbjct: 302 RTEHDRQLSEVENNIKKKACCCE------GFPFHEVIQEFLLNK-DKLVKVIRYQRPDLL 354
Query: 1223 MLVDCLVFNLHWDPCYVRKMLLPMLSTIYLREKARSSNTGNPL 1351
+ + + W Y + LL +L+ + E+ S N L
Sbjct: 355 LFQRFTLEKMEWPNHYACEKLLVLLTHYDMIERKLGSRNSNQL 397
>sp|Q29FC1|GEN_DROPS Flap endonuclease GEN OS=Drosophila pseudoobscura
pseudoobscura GN=Gen PE=3 SV=1
Length = 754
Score = 134 bits (335), Expect = 4e-030
Identities = 96/322 (29%), Positives = 153/322 (47%), Gaps = 32/322 (9%)
Frame = +2
Query: 86 MGVGGKFWDLVRPYGRNEGSDYLREKRVAVDLSFWIIQHETAVKGFA-LKPHLRLTFFRT 262
MGV + W ++ P+ + + LR K+VA+DL+ W+ + V F + HL+ FFRT
Sbjct: 1 MGV-KELWTVLTPHAERKPINELRGKKVAIDLAGWVCESLNVVDYFVHPRHHLKNLFFRT 59
Query: 263 INLFSKFGAYPVFVVDGTPSPLKSHTRISR----FYRSSGIDTSSLQEGVVSVERNK-QF 427
L + PVFV++G LK R F D ++ + V++ + +F
Sbjct: 60 CYLIWE-QVTPVFVLEGVAPKLKGQVIAKRNELQFRGVRPKDAATGTQTAAKVDKGRTRF 118
Query: 428 CEWVTECVELLKLLGIPVLKANGEAEALCAQLNSHGFVDACITPDSDAFLFGASSVIKSI 607
+ +C LL +GI ++ GEAEA A LN HG VD I+ DSD F +GA V ++
Sbjct: 119 NHVLKQCETLLLSMGIQCVQGPGEAEAYAAFLNKHGLVDGVISQDSDCFAYGAIRVYRNF 178
Query: 608 KPNST-------EPFECYHMSDIEAGLGLKRRHLIAISLLVGNDFDSGGVSGIGLDKALR 766
++ + Y M +I + + + +I ++LL G D+ G+ GIG D L+
Sbjct: 179 SVSTQGAQAAAGGAVDIYDMREITSRMDFGQHKIIVMALLCGCDYCPDGIGGIGKDGVLK 238
Query: 767 IVRAFSEDDILQRLEDIGKGFKPAVSGGTKSVDVDDDDDGVESSSQMKRRLPHCSRCGHP 946
+ + E +IL RL + A + ++++ DD + CS CGH
Sbjct: 239 LFNKYKESEILDRLRN-----WRAETDKYNALEMRVDDKSI------------CSNCGHI 281
Query: 947 GSKRSHFKSSCEHCSSDSGCIK 1012
G +SH KS C C + GC K
Sbjct: 282 GRTQSHTKSGCSVCRTKRGCDK 303
>sp|Q9VRJ0|GEN_DROME Flap endonuclease GEN OS=Drosophila melanogaster GN=Gen
PE=1 SV=1
Length = 726
Score = 132 bits (332), Expect = 8e-030
Identities = 95/321 (29%), Positives = 151/321 (47%), Gaps = 33/321 (10%)
Frame = +2
Query: 86 MGVGGKFWDLVRPYGRNEGSDYLREKRVAVDLSFWIIQHETAVKGFA-LKPHLRLTFFRT 262
MGV + W ++ P+ + + LR K+VA+DL+ W+ + V F + HL+ FFRT
Sbjct: 1 MGV-KELWGVLTPHCERKPINELRGKKVAIDLAGWVCESLNVVDYFVHPRHHLKNLFFRT 59
Query: 263 INLFSKFGAYPVFVVDGTPSPLKSHTRISR-FYRSSGIDTSSLQEGVVSV-----ERNKQ 424
L + PVFV++G LKS R + G+ + E S + +
Sbjct: 60 CYLIWE-QVTPVFVLEGVAPKLKSQVIAKRNELQFRGVKPKNSPECTQSQPSKGDKGRSR 118
Query: 425 FCEWVTECVELLKLLGIPVLKANGEAEALCAQLNSHGFVDACITPDSDAFLFGASSVIKS 604
F + +C LL +GI ++ GEAEA CA LN HG VD I+ DSD F +GA V ++
Sbjct: 119 FNHVLKQCETLLLSMGIQCVQGPGEAEAYCAFLNKHGLVDGVISQDSDCFAYGAVRVYRN 178
Query: 605 IKPNST-------EPFECYHMSDIEAGLGLKRRHLIAISLLVGNDFDSGGVSGIGLDKAL 763
++ + Y M +I + + ++ +I ++LL G D+ G+ GIG D L
Sbjct: 179 FSVSTQGAQAAAGGAVDIYDMREITSRMDFGQQKIIVMALLCGCDYCPDGIGGIGKDGVL 238
Query: 764 RIVRAFSEDDILQRLEDIGKGFKPAVSGGTKSVDVDDDDDGVESSSQMKRRLPHCSRCGH 943
++ + E +IL R+ + ++++ DD + CS CGH
Sbjct: 239 KLFNKYKETEILDRMRS-----WRGETDKYNALEIRVDDKSI------------CSNCGH 281
Query: 944 PGSKRSHFKSSCEHCSSDSGC 1006
G +SH KS C C + GC
Sbjct: 282 IGKTQSHTKSGCSVCRTHKGC 302
>sp|Q8W5R1|GENL2_ORYSJ Flap endonuclease GEN-like 2 OS=Oryza sativa subsp.
japonica GN=SEND1 PE=2 SV=1
Length = 641
Score = 121 bits (302), Expect = 3e-026
Identities = 93/271 (34%), Positives = 130/271 (47%), Gaps = 11/271 (4%)
Frame = +2
Query: 86 MGVGGKFWDLVRPYGRNEGSDYLREKRVAVDLSFWIIQHETAVKGFAL---KPHLRLTFF 256
MGV WD++ + +L+ K+V VDLS W++Q +A + A K +L+ F
Sbjct: 1 MGV-KNLWDILESCKKKLPLHHLQNKKVCVDLSCWLVQMYSANRSPAFAKDKVYLKNLFH 59
Query: 257 RTINLFSKFGAYPVFVVDGTPSPLKSHTRISRFYRSSGIDTSSLQEG---VVSVERNK-- 421
R I +FV DG LK T R S S Q +S+ RNK
Sbjct: 60 R-IRALLALNCTLLFVTDGAIPSLKLATYRRRLGSISHAAKESDQPNSHPSISLRRNKGS 118
Query: 422 QFCEWVTECVELLKLLGIPVLKANGEAEALCAQLNSHGFVDACITPDSDAFLFGASSVIK 601
+F + E L LGIP L EAEA CA L+ D C T DSDAFLFGA +V +
Sbjct: 119 EFSCMIKEAKRLGMALGIPCLDGLEEAEAQCASLDLESLCDGCFTSDSDAFLFGARTVYR 178
Query: 602 SIKPNSTEPFECYHMSDIEAGLGLKRRHLIAISLLVGNDFDSGGVSGIGLDKALRIVRAF 781
+ CY M DIE LG R LI++++L+G+D+ S GV+G G + A R+V++
Sbjct: 179 DVFIGEGGYVICYEMEDIEKTLGFGRNSLISLAVLLGSDY-SNGVNGFGPETACRLVKSV 237
Query: 782 SEDDILQRLEDIGKGFKPAVSGGTKSVDVDD 874
++ IL ++ G G VDD
Sbjct: 238 GDNLILDQILSNGVKATRKCKGKNSGNKVDD 268
>sp|Q9ATY5|UVH3_ARATH DNA repair protein UVH3 OS=Arabidopsis thaliana GN=UVH3
PE=2 SV=1
Length = 1479
Score = 108 bits (269), Expect = 2e-022
Identities = 66/159 (41%), Positives = 94/159 (59%), Gaps = 4/159 (2%)
Frame = +2
Query: 383 SLQEGVVSVERNKQ--FCEWVTECVELLKLLGIPVLKANGEAEALCAQLNSHGFVDACIT 556
SL + +ERN + E EC ELL++ GIP + A EAEA CA + VD +T
Sbjct: 906 SLGDEQRKLERNAESVSSEMFAECQELLQIFGIPYIIAPMEAEAQCAFMEQSNLVDGIVT 965
Query: 557 PDSDAFLFGASSVIKSIKPNSTEPFECYHMSDIEAGLGLKRRHLIAISLLVGNDFDSGGV 736
DSD FLFGA SV K+I + + E Y M DIE LGL R +I +++L+G+D+ + G+
Sbjct: 966 DDSDVFLFGARSVYKNIF-DDRKYVETYFMKDIEKELGLSRDKIIRMAMLLGSDY-TEGI 1023
Query: 737 SGIGLDKALRIVRAFSEDDILQRLEDIGKGFKPAVSGGT 853
SGIG+ A+ +V AF E+D LQ+ + + P + G T
Sbjct: 1024 SGIGIVNAIEVVTAFPEEDGLQKFREWVESPDPTILGKT 1062
>sp|Q9M2Z3|GENL2_ARATH Flap endonuclease GEN-like 2 OS=Arabidopsis thaliana
GN=GEN2 PE=2 SV=2
Length = 600
Score = 96 bits (238), Expect = 7e-019
Identities = 68/196 (34%), Positives = 96/196 (48%), Gaps = 4/196 (2%)
Frame = +2
Query: 251 FFRTINLFSKFGAYPVFVVDGTPSPLKSHTRISRFYRSSGIDTSSLQEG-VVSVERN--K 421
FF + + V DG +K T R I ++ S++RN
Sbjct: 57 FFHRLRALIALNCSIILVSDGAIPGIKVPTYKRRLKARFEIADDGVEPSKETSLKRNMGS 116
Query: 422 QFCEWVTECVELLKLLGIPVLKANGEAEALCAQLNSHGFVDACITPDSDAFLFGASSVIK 601
+F + E + LGI L EAEA CA LNS DAC + DSD FLFGA +V +
Sbjct: 117 EFSCIIKEAKVIASTLGILCLDGIEEAEAQCALLNSESLCDACFSFDSDIFLFGAKTVYR 176
Query: 602 SIKPNSTEPFECYHMSDIEAGLGLKRRHLIAISLLVGNDFDSGGVSGIGLDKALRIVRAF 781
I CY M DI+ LGL R LIA++LL+G+D+ S GV G+ +KA +VR+
Sbjct: 177 EICLGEGGYVVCYEMDDIKKKLGLGRNSLIALALLLGSDY-SQGVRGLRQEKACELVRSI 235
Query: 782 SEDDILQRLEDIGKGF 829
++ IL+++ G F
Sbjct: 236 GDNVILEKVASEGLSF 251
>sp|A6UX46|FEN_META3 Flap structure-specific endonuclease OS=Methanococcus
aeolicus (strain Nankai-3 / ATCC BAA-1280) GN=fen PE=3 SV=1
Length = 326
Score = 83 bits (203), Expect = 8e-015
Identities = 44/126 (34%), Positives = 73/126 (57%), Gaps = 1/126 (0%)
Frame = +2
Query: 437 VTECVELLKLLGIPVLKANGEAEALCAQLNSHGFVDACITPDSDAFLFGASSVIKSIKPN 616
V C +LLKL+GIP + A E EA CA + +G ++ D DA L+GA +++I
Sbjct: 132 VDNCKKLLKLMGIPYIDAPSEGEAQCAHMIKNGDAYCVVSQDYDALLYGAPRTVRNITA- 190
Query: 617 STEPFECYHMSDIEAGLGLKRRHLIAISLLVGNDFDSGGVSGIGLDKALRIVRAFSEDDI 796
S +P E + DI L + LI +++L+G D++ GG+ GIG KAL I++ ++
Sbjct: 191 SNKPLELMEIEDILKPLDISIDDLIDMAILIGTDYNIGGIKGIGPKKALTIIKNKKMNEY 250
Query: 797 LQRLED 814
++ +E+
Sbjct: 251 IKDIEN 256
>sp|P28706|RAD13_SCHPO DNA repair protein rad13 OS=Schizosaccharomyces pombe
GN=rad13 PE=2 SV=2
Length = 1112
Score = 74 bits (181), Expect = 3e-012
Identities = 44/118 (37%), Positives = 69/118 (58%), Gaps = 2/118 (1%)
Frame = +2
Query: 437 VTECVELLKLLGIPVLKANGEAEALCAQLNSHGFVDACITPDSDAFLFGASSVIKSIKPN 616
+ EC ELL+L G+P + A EAEA C++L VD +T DSD FLFG + V +++ N
Sbjct: 757 IKECQELLRLFGLPYIVAPQEAEAQCSKLLELKLVDGIVTDDSDVFLFGGTRVYRNMF-N 815
Query: 617 STEPFECYHMSDIEAGLGLKRRHLIAISLLVGNDFDSGGVSGIGLDKALRIVRAFSED 790
+ E Y M D++ + + LI ++ L+G+D+ + G+S +G AL I+ F D
Sbjct: 816 QNKFVELYLMDDMKREFNVNQMDLIKLAHLLGSDY-TMGLSRVGPVLALEILHEFPGD 872
>sp|P07276|RAD2_YEAST DNA repair protein RAD2 OS=Saccharomyces cerevisiae
GN=RAD2 PE=1 SV=2
Length = 1031
Score = 72 bits (175), Expect = 1e-011
Identities = 42/117 (35%), Positives = 66/117 (56%), Gaps = 2/117 (1%)
Frame = +2
Query: 431 EWVTECVELLKLLGIPVLKANGEAEALCAQLNSHGFVDACITPDSDAFLFGASSVIKSIK 610
+ + E ELL GIP + A EAEA CA+L VD IT DSD FLFG + + K++
Sbjct: 770 DMIKEVQELLSRFGIPYITAPMEAEAQCAELLQLNLVDGIITDDSDVFLFGGTKIYKNMF 829
Query: 611 PNSTEPFECYHMSDIEAGLGLKRRHLIAISLLVGNDFDSGGVSGIGLDKALRIVRAF 781
+ E Y I LGL R+++I ++ L+G+D+ + G+ G+G ++ ++ F
Sbjct: 830 -HEKNYVEFYDAESILKLLGLDRKNMIELAQLLGSDY-TNGLKGMGPVSSIEVIAEF 884
>sp|P35689|ERCC5_MOUSE DNA repair protein complementing XP-G cells homolog
OS=Mus musculus GN=Ercc5 PE=1 SV=3
Length = 1170
Score = 70 bits (171), Expect = 4e-011
Identities = 44/113 (38%), Positives = 63/113 (55%), Gaps = 2/113 (1%)
Frame = +2
Query: 443 ECVELLKLLGIPVLKANGEAEALCAQLNSHGFVDACITPDSDAFLFGASSVIKSIKPNST 622
E ELL+L G+P ++A EAEA CA L+ IT DSD +LFGA V K+ N
Sbjct: 770 ESQELLRLFGVPYIQAPMEAEAQCAMLDLSDQTSGTITDDSDIWLFGARHVYKNFF-NKN 828
Query: 623 EPFECYHMSDIEAGLGLKRRHLIAISLLVGNDFDSGGVSGIGLDKALRIVRAF 781
+ E Y D + LGL R LI ++ L+G+D+ + G+ +G A+ I+ F
Sbjct: 829 KFVEYYQYVDFYSQLGLDRNKLINLAYLLGSDY-TEGIPTVGCVTAMEILNEF 880
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 159,249,259,203
Number of Sequences: 518415
Number of Extensions: 159249259203
Number of Successful Extensions: 968868021
Number of sequences better than 0.0: 0
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