BLASTX 7.6.2
Query= UN41503 /QuerySize=1163
(1162 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P93033|FUM1_ARATH Fumarate hydratase 1, mitochondrial OS=Arab... 182 5e-045
sp|Q9FI53|FUM2_ARATH Fumarate hydratase 2, chloroplastic OS=Arab... 178 9e-044
sp|Q54VA2|FUMH_DICDI Fumarate hydratase, mitochondrial OS=Dictyo... 141 2e-032
sp|O17214|FUMH_CAEEL Probable fumarate hydratase, mitochondrial ... 136 3e-031
sp|P55250|FUMH_RHIOR Fumarate hydratase, mitochondrial OS=Rhizop... 136 4e-031
sp|O94552|FUMH_SCHPO Fumarate hydratase, mitochondrial OS=Schizo... 134 2e-030
sp|P07954|FUMH_HUMAN Fumarate hydratase, mitochondrial OS=Homo s... 133 2e-030
sp|Q60HF9|FUMH_MACFA Fumarate hydratase, mitochondrial OS=Macaca... 133 3e-030
sp|Q7VKC9|FUMC_HAEDU Fumarate hydratase class II OS=Haemophilus ... 132 7e-030
sp|P10173|FUMH_PIG Fumarate hydratase, mitochondrial OS=Sus scro... 131 9e-030
sp|P14408|FUMH_RAT Fumarate hydratase, mitochondrial OS=Rattus n... 131 9e-030
sp|P97807|FUMH_MOUSE Fumarate hydratase, mitochondrial OS=Mus mu... 130 2e-029
sp|Q9CMK1|FUMC_PASMU Fumarate hydratase class II OS=Pasteurella ... 130 3e-029
sp|Q7SX99|FUMH_DANRE Fumarate hydratase, mitochondrial OS=Danio ... 130 3e-029
sp|Q72VY3|FUMC_LEPIC Fumarate hydratase class II OS=Leptospira i... 129 4e-029
sp|Q8F9L0|FUMC_LEPIN Fumarate hydratase class II OS=Leptospira i... 129 4e-029
sp|P71384|FUMC_HAEIN Fumarate hydratase class II OS=Haemophilus ... 128 8e-029
sp|P08417|FUMH_YEAST Fumarate hydratase, mitochondrial OS=Saccha... 126 3e-028
>sp|P93033|FUM1_ARATH Fumarate hydratase 1, mitochondrial OS=Arabidopsis
thaliana GN=FUM1 PE=1 SV=2
Length = 492
Score = 182 bits (461), Expect = 5e-045
Identities = 89/97 (91%), Positives = 93/97 (95%)
Frame = -2
Query: 459 QSFEFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAVG 280
+SFEFKDIVKIGRTHTQDATPLTL QEF GY+TQVKYGLNRVTCTLPRLYQLAQGGTAVG
Sbjct: 202 KSFEFKDIVKIGRTHTQDATPLTLGQEFGGYATQVKYGLNRVTCTLPRLYQLAQGGTAVG 261
Query: 279 TGLNTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
TGLNTKKGFDVKIAA VA+ETNLPFVTAENKFEAL +
Sbjct: 262 TGLNTKKGFDVKIAAAVAEETNLPFVTAENKFEALAA 298
Score = 146 bits (366), Expect = 5e-034
Identities = 69/72 (95%), Positives = 72/72 (100%)
Frame = -3
Query: 848 QVWGAQTQRSLQNFEIGGERERMPEPIVRAFGVLKKCAAKVNMEYGLDPTIGKAIMEAAQ 669
++WGAQTQRSLQNFEIGGERERMPEPIVRAFGVLKKCAAKVNMEYGLDPTIGKAIM+AAQ
Sbjct: 48 KLWGAQTQRSLQNFEIGGERERMPEPIVRAFGVLKKCAAKVNMEYGLDPTIGKAIMQAAQ 107
Query: 668 EVAEGKLNDHFP 633
EVAEGKLNDHFP
Sbjct: 108 EVAEGKLNDHFP 119
>sp|Q9FI53|FUM2_ARATH Fumarate hydratase 2, chloroplastic OS=Arabidopsis
thaliana GN=FUM2 PE=2 SV=1
Length = 499
Score = 178 bits (450), Expect = 9e-044
Identities = 86/97 (88%), Positives = 92/97 (94%)
Frame = -2
Query: 459 QSFEFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAVG 280
+SFEFKDIVKIGRTHTQDATPLTL QEF GY+TQV+YGLNRV CTLPR+YQLAQGGTAVG
Sbjct: 209 KSFEFKDIVKIGRTHTQDATPLTLGQEFGGYATQVEYGLNRVACTLPRIYQLAQGGTAVG 268
Query: 279 TGLNTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
TGLNTKKGFDVKIAA VA+ETNLPFVTAENKFEAL +
Sbjct: 269 TGLNTKKGFDVKIAAAVAEETNLPFVTAENKFEALAA 305
Score = 142 bits (356), Expect = 7e-033
Identities = 67/72 (93%), Positives = 71/72 (98%)
Frame = -3
Query: 848 QVWGAQTQRSLQNFEIGGERERMPEPIVRAFGVLKKCAAKVNMEYGLDPTIGKAIMEAAQ 669
++WGAQTQRSLQNFEIGG+RERMPEPIVRAFGVLKKCAAKVNMEYGLDP IG+AIMEAAQ
Sbjct: 55 KLWGAQTQRSLQNFEIGGDRERMPEPIVRAFGVLKKCAAKVNMEYGLDPMIGEAIMEAAQ 114
Query: 668 EVAEGKLNDHFP 633
EVAEGKLNDHFP
Sbjct: 115 EVAEGKLNDHFP 126
>sp|Q54VA2|FUMH_DICDI Fumarate hydratase, mitochondrial OS=Dictyostelium
discoideum GN=fumH PE=3 SV=1
Length = 485
Score = 141 bits (353), Expect = 2e-032
Identities = 69/94 (73%), Positives = 77/94 (81%)
Frame = -2
Query: 450 EFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAVGTGL 271
EF I+KIGRTH QDATPLTL QEFSGY TQ++YG+ R+ TLPRLY LAQGGTAVGTGL
Sbjct: 198 EFNHIIKIGRTHLQDATPLTLGQEFSGYCTQIEYGIQRIKDTLPRLYNLAQGGTAVGTGL 257
Query: 270 NTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
NT GFDV IA+EVA+ T LPF TA NKFEAL +
Sbjct: 258 NTPVGFDVDIASEVAKFTGLPFKTAPNKFEALAA 291
>sp|O17214|FUMH_CAEEL Probable fumarate hydratase, mitochondrial
OS=Caenorhabditis elegans GN=fum-1 PE=1 SV=1
Length = 501
Score = 136 bits (342), Expect = 3e-031
Identities = 68/94 (72%), Positives = 76/94 (80%)
Frame = -2
Query: 450 EFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAVGTGL 271
EFKDI+KIGRTHTQDA PLTL QEFS Y TQ+ + RV TLPRLYQLA GGTAVGTGL
Sbjct: 215 EFKDIIKIGRTHTQDAVPLTLGQEFSAYVTQLDNSIARVESTLPRLYQLAAGGTAVGTGL 274
Query: 270 NTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
NT+KGF K+AA V++ T LPFVTA NKFEAL +
Sbjct: 275 NTRKGFAEKVAATVSELTGLPFVTAPNKFEALAA 308
>sp|P55250|FUMH_RHIOR Fumarate hydratase, mitochondrial OS=Rhizopus oryzae
GN=FUMR PE=3 SV=1
Length = 494
Score = 136 bits (341), Expect = 4e-031
Identities = 67/97 (69%), Positives = 77/97 (79%)
Frame = -2
Query: 459 QSFEFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAVG 280
+S EF+ I+KIGRTH QDATPLTL QEFSGY+ Q+ YG+ RV TL RLY LAQGGTAVG
Sbjct: 204 KSAEFEHIIKIGRTHLQDATPLTLGQEFSGYTQQLTYGIARVQGTLERLYNLAQGGTAVG 263
Query: 279 TGLNTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
TGLNT+KGFD K+A +A T LPF TA NKFEAL +
Sbjct: 264 TGLNTRKGFDAKVAEAIASITGLPFKTAPNKFEALAA 300
>sp|O94552|FUMH_SCHPO Fumarate hydratase, mitochondrial OS=Schizosaccharomyces
pombe GN=fum1 PE=2 SV=3
Length = 520
Score = 134 bits (335), Expect = 2e-030
Identities = 66/98 (67%), Positives = 79/98 (80%)
Frame = -2
Query: 462 GQSFEFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAV 283
G+ EFK+I+KIGRTH QDATPL+L QEFSGY TQV YG+ R+ LPRL LAQGGTAV
Sbjct: 228 GKEEEFKNIIKIGRTHMQDATPLSLGQEFSGYVTQVGYGIERINNALPRLCLLAQGGTAV 287
Query: 282 GTGLNTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
GTGLNT +GFDVK+A +V++ TN+ F TA NKFEAL +
Sbjct: 288 GTGLNTFEGFDVKVAEKVSKLTNIEFKTAPNKFEALAA 325
>sp|P07954|FUMH_HUMAN Fumarate hydratase, mitochondrial OS=Homo sapiens GN=FH
PE=1 SV=3
Length = 510
Score = 133 bits (334), Expect = 2e-030
Identities = 65/97 (67%), Positives = 76/97 (78%)
Frame = -2
Query: 459 QSFEFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAVG 280
+S EF I+KIGRTHTQDA PLTL QEFSGY QVKY + R+ +PR+Y+LA GGTAVG
Sbjct: 221 KSKEFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVG 280
Query: 279 TGLNTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
TGLNT+ GF K+AA+VA T LPFVTA NKFEAL +
Sbjct: 281 TGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAA 317
>sp|Q60HF9|FUMH_MACFA Fumarate hydratase, mitochondrial OS=Macaca fascicularis
GN=FH PE=2 SV=1
Length = 510
Score = 133 bits (333), Expect = 3e-030
Identities = 65/97 (67%), Positives = 76/97 (78%)
Frame = -2
Query: 459 QSFEFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAVG 280
+S EF I+KIGRTHTQDA PLTL QEFSGY QVKY + R+ +PR+Y+LA GGTAVG
Sbjct: 221 KSKEFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAVTRIKAAMPRIYELAAGGTAVG 280
Query: 279 TGLNTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
TGLNT+ GF K+AA+VA T LPFVTA NKFEAL +
Sbjct: 281 TGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAA 317
>sp|Q7VKC9|FUMC_HAEDU Fumarate hydratase class II OS=Haemophilus ducreyi GN=fumC
PE=3 SV=1
Length = 464
Score = 132 bits (330), Expect = 7e-030
Identities = 65/97 (67%), Positives = 77/97 (79%)
Frame = -2
Query: 459 QSFEFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAVG 280
+S FKD+VKIGRTH DATPLTL QEFS Y+ Q+++GL + TLP L QLA GGTAVG
Sbjct: 174 KSEAFKDVVKIGRTHLMDATPLTLGQEFSAYAAQLQFGLLALKNTLPHLAQLALGGTAVG 233
Query: 279 TGLNTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
TGLNT KG+DVK+A +AQ T LPF+TAENKFEAL +
Sbjct: 234 TGLNTPKGYDVKVAEYIAQFTQLPFITAENKFEALAT 270
>sp|P10173|FUMH_PIG Fumarate hydratase, mitochondrial OS=Sus scrofa GN=FH PE=1
SV=1
Length = 466
Score = 131 bits (329), Expect = 9e-030
Identities = 64/97 (65%), Positives = 75/97 (77%)
Frame = -2
Query: 459 QSFEFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAVG 280
+S EF I+KIGRTHTQDA PLTL QEFSGY QVKY + R+ +PR+Y+LA GGTAVG
Sbjct: 177 KSREFAQIIKIGRTHTQDAVPLTLGQEFSGYVQQVKYAITRIKAAMPRIYELAAGGTAVG 236
Query: 279 TGLNTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
TGLNT+ GF K+AA+VA T LPFVTA N FEAL +
Sbjct: 237 TGLNTRIGFAEKVAAKVAALTGLPFVTAPNNFEALAA 273
>sp|P14408|FUMH_RAT Fumarate hydratase, mitochondrial OS=Rattus norvegicus GN=Fh
PE=1 SV=1
Length = 507
Score = 131 bits (329), Expect = 9e-030
Identities = 63/97 (64%), Positives = 76/97 (78%)
Frame = -2
Query: 459 QSFEFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAVG 280
+S EF ++KIGRTHTQDA PLTL QEFSGY QV+Y + R+ +PR+Y+LA GGTAVG
Sbjct: 218 KSKEFAQVIKIGRTHTQDAVPLTLGQEFSGYVQQVQYAMERIKAAMPRIYELAAGGTAVG 277
Query: 279 TGLNTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
TGLNT+ GF K+AA+VA T LPFVTA NKFEAL +
Sbjct: 278 TGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAA 314
>sp|P97807|FUMH_MOUSE Fumarate hydratase, mitochondrial OS=Mus musculus GN=Fh
PE=1 SV=2
Length = 507
Score = 130 bits (326), Expect = 2e-029
Identities = 63/97 (64%), Positives = 76/97 (78%)
Frame = -2
Query: 459 QSFEFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAVG 280
+S EF ++KIGRTHTQDA PLTL QEFSGY QV+Y + R+ +PR+Y+LA GGTAVG
Sbjct: 218 KSKEFAQVIKIGRTHTQDAVPLTLGQEFSGYVQQVQYAMVRIKAAMPRIYELAAGGTAVG 277
Query: 279 TGLNTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
TGLNT+ GF K+AA+VA T LPFVTA NKFEAL +
Sbjct: 278 TGLNTRIGFAEKVAAKVAALTGLPFVTAPNKFEALAA 314
>sp|Q9CMK1|FUMC_PASMU Fumarate hydratase class II OS=Pasteurella multocida
GN=fumC PE=3 SV=1
Length = 464
Score = 130 bits (325), Expect = 3e-029
Identities = 63/93 (67%), Positives = 74/93 (79%)
Frame = -2
Query: 447 FKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAVGTGLN 268
FKD+VKIGRTH DATPLTL QEFS Y+ Q+ +GL + TLP L QLA GGTAVGTGLN
Sbjct: 178 FKDVVKIGRTHLMDATPLTLGQEFSAYAAQLDFGLRALKNTLPHLAQLALGGTAVGTGLN 237
Query: 267 TKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
T KG+DVK+A +A+ T LPF+TAENKFEAL +
Sbjct: 238 TPKGYDVKVADYIAKFTGLPFITAENKFEALAT 270
>sp|Q7SX99|FUMH_DANRE Fumarate hydratase, mitochondrial OS=Danio rerio GN=fh
PE=2 SV=1
Length = 509
Score = 130 bits (325), Expect = 3e-029
Identities = 63/94 (67%), Positives = 75/94 (79%)
Frame = -2
Query: 450 EFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAVGTGL 271
+FKDI+KIGRTHTQDA PL+L QEF GY QVKY + RV +LPR+Y+LA GGTAVGTGL
Sbjct: 223 QFKDIIKIGRTHTQDAVPLSLGQEFGGYVQQVKYSIARVKASLPRVYELAAGGTAVGTGL 282
Query: 270 NTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
NT+ GF K+A +V+ T LPFVTA NKFEAL +
Sbjct: 283 NTRIGFAEKVADKVSALTGLPFVTAANKFEALAA 316
>sp|Q72VY3|FUMC_LEPIC Fumarate hydratase class II OS=Leptospira interrogans
serogroup Icterohaemorrhagiae serovar copenhageni GN=fumC PE=3 SV=1
Length = 464
Score = 129 bits (324), Expect = 4e-029
Identities = 63/94 (67%), Positives = 76/94 (80%)
Frame = -2
Query: 450 EFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAVGTGL 271
EF++I+KIGRTH QDATPLTL QEFSGY Q++Y + RV LP +Y+LA GGTAVGTGL
Sbjct: 176 EFQNIIKIGRTHLQDATPLTLGQEFSGYVQQLEYNIARVKAVLPSVYRLALGGTAVGTGL 235
Query: 270 NTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
NT F VK AA++A+ET LPFV+AENKFEAL +
Sbjct: 236 NTHPQFAVKAAAQIAKETGLPFVSAENKFEALAA 269
>sp|Q8F9L0|FUMC_LEPIN Fumarate hydratase class II OS=Leptospira interrogans
GN=fumC PE=3 SV=1
Length = 464
Score = 129 bits (324), Expect = 4e-029
Identities = 63/94 (67%), Positives = 76/94 (80%)
Frame = -2
Query: 450 EFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAVGTGL 271
EF++I+KIGRTH QDATPLTL QEFSGY Q++Y + RV LP +Y+LA GGTAVGTGL
Sbjct: 176 EFQNIIKIGRTHLQDATPLTLGQEFSGYVQQLEYNIARVKAVLPSVYRLALGGTAVGTGL 235
Query: 270 NTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
NT F VK AA++A+ET LPFV+AENKFEAL +
Sbjct: 236 NTHPQFAVKAAAQIAKETGLPFVSAENKFEALAA 269
>sp|P71384|FUMC_HAEIN Fumarate hydratase class II OS=Haemophilus influenzae
GN=fumC PE=3 SV=1
Length = 464
Score = 128 bits (321), Expect = 8e-029
Identities = 66/116 (56%), Positives = 83/116 (71%), Gaps = 3/116 (2%)
Frame = -2
Query: 516 DHVICCVC*FSRTYFLILGQSFEFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNR 337
+H I CV +T+ +S FK++VKIGRTH DATPLTL QEFS Y+ Q+ +GL
Sbjct: 158 EHTIPCVERLQKTF---AAKSEAFKNVVKIGRTHLMDATPLTLGQEFSAYAAQLDFGLKA 214
Query: 336 VTCTLPRLYQLAQGGTAVGTGLNTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
+ TLP L QLA GGTAVGTGLNT KG+D+K+ +A+ T LPFVTA+NKFEAL +
Sbjct: 215 LKNTLPHLSQLALGGTAVGTGLNTPKGYDLKVVDYIAKFTALPFVTADNKFEALAA 270
>sp|P08417|FUMH_YEAST Fumarate hydratase, mitochondrial OS=Saccharomyces
cerevisiae GN=FUM1 PE=1 SV=2
Length = 488
Score = 126 bits (316), Expect = 3e-028
Identities = 66/97 (68%), Positives = 75/97 (77%)
Frame = -2
Query: 459 QSFEFKDIVKIGRTHTQDATPLTLAQEFSGYSTQVKYGLNRVTCTLPRLYQLAQGGTAVG 280
+S EF IVKIGRTH QDATPLTL QEFSGY QV+ G+ RV +L L LAQGGTAVG
Sbjct: 199 KSKEFDHIVKIGRTHLQDATPLTLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVG 258
Query: 279 TGLNTKKGFDVKIAAEVAQETNLPFVTAENKFEALVS 169
TGLNTK GFDVKIA ++++ET L F TA NKFEAL +
Sbjct: 259 TGLNTKPGFDVKIAEQISKETGLKFQTAPNKFEALAA 295
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 159,249,259,203
Number of Sequences: 518415
Number of Extensions: 159249259203
Number of Successful Extensions: 968868021
Number of sequences better than 0.0: 0
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