BLASTX 7.6.2
Query= UN42695 /QuerySize=1053
(1052 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P93836|HPPD_ARATH 4-hydroxyphenylpyruvate dioxygenase OS=Arab... 514 4e-145
sp|O23920|HPPD_DAUCA 4-hydroxyphenylpyruvate dioxygenase OS=Dauc... 453 2e-126
sp|Q9ARF9|HPPD_SOLSC 4-hydroxyphenylpyruvate dioxygenase OS=Sole... 436 2e-121
sp|O48604|HPPD_HORVU 4-hydroxyphenylpyruvate dioxygenase OS=Hord... 395 3e-109
sp|Q6TGZ5|HPPD_DANRE 4-hydroxyphenylpyruvate dioxygenase OS=Dani... 154 2e-036
sp|Q5BKL0|HPPD_XENTR 4-hydroxyphenylpyruvate dioxygenase OS=Xeno... 152 6e-036
sp|Q6CDR5|HPPD_YARLI 4-hydroxyphenylpyruvate dioxygenase OS=Yarr... 151 1e-035
sp|Q5EA20|HPPD_BOVIN 4-hydroxyphenylpyruvate dioxygenase OS=Bos ... 150 2e-035
sp|P32754|HPPD_HUMAN 4-hydroxyphenylpyruvate dioxygenase OS=Homo... 147 1e-034
sp|Q872T7|HPPD_NEUCR 4-hydroxyphenylpyruvate dioxygenase OS=Neur... 146 2e-034
sp|P32755|HPPD_RAT 4-hydroxyphenylpyruvate dioxygenase OS=Rattus... 145 5e-034
sp|Q27203|HPPD_TETTH 4-hydroxyphenylpyruvate dioxygenase OS=Tetr... 145 5e-034
sp|Q96X22|HPPD_MAGGR 4-hydroxyphenylpyruvate dioxygenase OS=Magn... 144 9e-034
sp|Q02110|HPPD_PIG 4-hydroxyphenylpyruvate dioxygenase OS=Sus sc... 144 1e-033
sp|O42764|HPPD_MYCGR 4-hydroxyphenylpyruvate dioxygenase OS=Myco... 144 2e-033
sp|P49429|HPPD_MOUSE 4-hydroxyphenylpyruvate dioxygenase OS=Mus ... 141 8e-033
sp|Q60Y65|HPPD_CAEBR 4-hydroxyphenylpyruvate dioxygenase OS=Caen... 139 3e-032
sp|Q53586|HPPD_STRAW 4-hydroxyphenylpyruvate dioxygenase OS=Stre... 136 3e-031
sp|Q1E803|HPPD_COCIM 4-hydroxyphenylpyruvate dioxygenase OS=Cocc... 136 3e-031
sp|Q00415|HPPD_COCP7 4-hydroxyphenylpyruvate dioxygenase OS=Cocc... 135 7e-031
>sp|P93836|HPPD_ARATH 4-hydroxyphenylpyruvate dioxygenase OS=Arabidopsis
thaliana GN=HPD PE=1 SV=2
Length = 445
Score = 514 bits (1323), Expect = 4e-145
Identities = 256/293 (87%), Positives = 272/293 (92%), Gaps = 2/293 (0%)
Frame = +3
Query: 87 FSISVSNGAVPSSPPILLNDAVTISEVKLYGDVVLRYVSYNKAVT--SVFLPRFEPVEDT 260
FSISV+NGA+PSSPPI+LN+AVTI+EVKLYGDVVLRYVSY T S FLP FE VED
Sbjct: 153 FSISVANGAIPSSPPIVLNEAVTIAEVKLYGDVVLRYVSYKAEDTEKSEFLPGFERVEDA 212
Query: 261 SSFPLDYGITRLDHAVGNVPELVPALTYLATFTGFHQFAEFTADDVGTAESGLNSAVLAN 440
SSFPLDYGI RLDHAVGNVPEL PALTY+A FTGFHQFAEFTADDVGTAESGLNSAVLA+
Sbjct: 213 SSFPLDYGIRRLDHAVGNVPELGPALTYVAGFTGFHQFAEFTADDVGTAESGLNSAVLAS 272
Query: 441 NDETVLLPINEPVHGTRRKSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKRSGVGGF 620
NDE VLLPINEPVHGT+RKSQIQTYLEHNEGAG+QHLAL S DIFRTLREMRKRS +GGF
Sbjct: 273 NDEMVLLPINEPVHGTKRKSQIQTYLEHNEGAGLQHLALMSEDIFRTLREMRKRSSIGGF 332
Query: 621 DFMPSPPPTYYKNLKKRVGDVLSEEEIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIF 800
DFMPSPPPTYY+NLKKRVGDVLS+++IKECEELGILVDRDDQGTLLQIFTKPLGDRPTIF
Sbjct: 333 DFMPSPPPTYYQNLKKRVGDVLSDDQIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIF 392
Query: 801 IEIIQRIGCMKKDGEGKVYQSGGCGGFGKGNFSELLKSIEEYEKTLEAKQLLG 959
IEIIQR+GCM KD EGK YQSGGCGGFGKGNFSEL KSIEEYEKTLEAKQL+G
Sbjct: 393 IEIIQRVGCMMKDEEGKAYQSGGCGGFGKGNFSELFKSIEEYEKTLEAKQLVG 445
>sp|O23920|HPPD_DAUCA 4-hydroxyphenylpyruvate dioxygenase OS=Daucus carota PE=2
SV=1
Length = 442
Score = 453 bits (1163), Expect = 2e-126
Identities = 223/292 (76%), Positives = 254/292 (86%), Gaps = 2/292 (0%)
Frame = +3
Query: 87 FSISVSNGAVPSSPPILLNDAVTISEVKLYGDVVLRYVSYNKAVTSVFLPRFEPVEDTSS 266
F SV+ GA P+S P+ L+D ++EV+LYGDVVLR+VS+ + +FLP FE VE T+S
Sbjct: 148 FEASVARGARPASAPVELDDQAWLAEVELYGDVVLRFVSFGRE-EGLFLPGFEAVEGTAS 206
Query: 267 FP-LDYGITRLDHAVGNVPELVPALTYLATFTGFHQFAEFTADDVGTAESGLNSAVLANN 443
FP LDYGI RLDHAVGNV EL P + Y+ FTGFH+FAEFTA+DVGT ESGLNS VLANN
Sbjct: 207 FPDLDYGIRRLDHAVGNVTELGPVVEYIKGFTGFHEFAEFTAEDVGTLESGLNSVVLANN 266
Query: 444 DETVLLPINEPVHGTRRKSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKRSGVGGFD 623
+E VLLP+NEPV+GT+RKSQIQTYLEHNEGAGVQHLAL S DIFRTLREMRKRS +GGF+
Sbjct: 267 EEMVLLPLNEPVYGTKRKSQIQTYLEHNEGAGVQHLALVSEDIFRTLREMRKRSCLGGFE 326
Query: 624 FMPSPPPTYYKNLKKRVGDVLSEEEIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFI 803
FMPSPPPTYYKNLK RVGDVLS+E+IKECE+LGILVDRDDQGTLLQIFTKP+GDRPT+FI
Sbjct: 327 FMPSPPPTYYKNLKNRVGDVLSDEQIKECEDLGILVDRDDQGTLLQIFTKPVGDRPTLFI 386
Query: 804 EIIQRIGCMKKDGEGKVYQSGGCGGFGKGNFSELLKSIEEYEKTLEAKQLLG 959
EIIQR+GCM KD G++YQ GGCGGFGKGNFSEL KSIEEYEKTLEAKQ+ G
Sbjct: 387 EIIQRVGCMLKDDAGQMYQKGGCGGFGKGNFSELFKSIEEYEKTLEAKQITG 438
>sp|Q9ARF9|HPPD_SOLSC 4-hydroxyphenylpyruvate dioxygenase OS=Solenostemon
scutellarioides PE=2 SV=1
Length = 436
Score = 436 bits (1120), Expect = 2e-121
Identities = 216/289 (74%), Positives = 244/289 (84%), Gaps = 2/289 (0%)
Frame = +3
Query: 87 FSISVSNGAVPSSPPILLNDAVT-ISEVKLYGDVVLRYVSYNKAVTSVFLPRFEPVED-T 260
+S +VS GA P SPP++L D T I+EV LYGD VLR+VS FLP FE V D
Sbjct: 140 YSAAVSRGAKPVSPPVVLADCETAIAEVHLYGDTVLRFVSCGSGADGWFLPGFEVVGDGV 199
Query: 261 SSFPLDYGITRLDHAVGNVPELVPALTYLATFTGFHQFAEFTADDVGTAESGLNSAVLAN 440
S LDYGI RLDHAVGNVP+L P + YL FTGFH+FAEFTA+DVGTAESGLNS VLAN
Sbjct: 200 SCQELDYGIRRLDHAVGNVPKLEPVVDYLKKFTGFHEFAEFTAEDVGTAESGLNSVVLAN 259
Query: 441 NDETVLLPINEPVHGTRRKSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKRSGVGGF 620
N+E VL P+NEPV+GT+RKSQIQTYL+HNEGAGVQHLAL + DIFRTLREMRKRS VGGF
Sbjct: 260 NNENVLFPLNEPVYGTKRKSQIQTYLDHNEGAGVQHLALITEDIFRTLREMRKRSEVGGF 319
Query: 621 DFMPSPPPTYYKNLKKRVGDVLSEEEIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIF 800
+FMPSPPPTYY+NLK R GDVLS+E+I+ECE+LGIL+DRDDQGTLLQIFTKP+GDRPT+F
Sbjct: 320 EFMPSPPPTYYRNLKSRAGDVLSDEQIEECEKLGILIDRDDQGTLLQIFTKPVGDRPTLF 379
Query: 801 IEIIQRIGCMKKDGEGKVYQSGGCGGFGKGNFSELLKSIEEYEKTLEAK 947
IEIIQR+GCM KD EGK+YQ GGCGGFGKGNFSEL KSIEEYEK LE+K
Sbjct: 380 IEIIQRVGCMMKDEEGKMYQKGGCGGFGKGNFSELFKSIEEYEKMLESK 428
>sp|O48604|HPPD_HORVU 4-hydroxyphenylpyruvate dioxygenase OS=Hordeum vulgare
PE=2 SV=1
Length = 434
Score = 395 bits (1014), Expect = 3e-109
Identities = 191/288 (66%), Positives = 229/288 (79%), Gaps = 2/288 (0%)
Frame = +3
Query: 87 FSISVSNGAVPSSPPILLNDAVTISEVKLYGDVVLRYVSYNKAVTSVFLPRFEPVEDTSS 266
F S GA P+ P+ L +EV+LYGDVVLR+VS+ FLP FE V T+
Sbjct: 142 FRASRRRGARPAFAPVDLGRGFAFAEVELYGDVVLRFVSHPDGTDVPFLPGFEGV--TNP 199
Query: 267 FPLDYGITRLDHAVGNVPELVPALTYLATFTGFHQFAEFTADDVGTAESGLNSAVLANND 446
+DYG+TR DH VGNVPEL PA Y+A FTGFH+FAEFTA+DVGT ESGLNS VLANN
Sbjct: 200 DAVDYGLTRFDHVVGNVPELAPAAAYIAGFTGFHEFAEFTAEDVGTTESGLNSVVLANNS 259
Query: 447 ETVLLPINEPVHGTRRKSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKRSGVGGFDF 626
E VLLP+NEPVHGT+R+SQIQT+LEH+ G GVQH+A+ S D+ RTLR+MR RS +GGFDF
Sbjct: 260 EGVLLPLNEPVHGTKRRSQIQTFLEHHGGPGVQHIAVASSDVLRTLRKMRARSAMGGFDF 319
Query: 627 MPSPPPTYYKNLKKRVGDVLSEEEIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIE 806
+P P P YY+ +++ GDVLSE +IKEC+ELG+LVDRDDQG LLQIFTKP+GDRPT+F+E
Sbjct: 320 LPPPLPKYYEGVRRLAGDVLSEAQIKECQELGVLVDRDDQGVLLQIFTKPVGDRPTLFLE 379
Query: 807 IIQRIGCMKKDGEGKVYQSGGCGGFGKGNFSELLKSIEEYEKTLEAKQ 950
+IQRIGCM+KD G+ YQ GGCGGFGKGNFSEL KSIE+YEK+LEAKQ
Sbjct: 380 MIQRIGCMEKDERGEEYQKGGCGGFGKGNFSELFKSIEDYEKSLEAKQ 427
>sp|Q6TGZ5|HPPD_DANRE 4-hydroxyphenylpyruvate dioxygenase OS=Danio rerio GN=hpd
PE=2 SV=1
Length = 397
Score = 154 bits (387), Expect = 2e-036
Identities = 98/247 (39%), Positives = 145/247 (58%), Gaps = 16/247 (6%)
Frame = +3
Query: 108 GAVPSSPPILLNDA---VTISEVKLYGDVVLRYVSYNKAVTSVFLPRF-EPVEDTSSFP- 272
GA P + DA V + V+ YGD +V Y +FLP + EP+ P
Sbjct: 114 GAAVLKEPWVEQDAGGKVKYAIVQTYGDTTHTFVEYLGPYKGLFLPGYKEPLFRDPLLPK 173
Query: 273 LDYG-ITRLDHAVGNVP--ELVPALTYLATFTGFHQFAEFTADDVGTAESGLNSAVLANN 443
L G ++ +DH VGN P E+VP + FH+F + T S L S V+ N
Sbjct: 174 LPSGHLSFIDHIVGNQPDDEMVPVSDWYQKCLLFHRFWSIDDKQIHTEYSALRSIVVTNY 233
Query: 444 DETVLLPINEPVHGTRRKSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKRSGVGGFD 623
+ET+ +PINEP G ++KSQIQ Y+++N G GVQH+AL + +I + + +R R G +
Sbjct: 234 EETIKMPINEPAMG-KKKSQIQEYIDYNGGPGVQHIALNTSNIIQAIVNLRAR----GLE 288
Query: 624 FMPSPPPTYYKNLKKRV--GDVLSEEEIKECEELGILVDRDDQGTLLQIFTKPLGDRPTI 797
F+ S P YY++L++++ + +E++K +EL ILVD DD+G LLQIFTKP+ DRPT+
Sbjct: 289 FL-SAPDNYYESLREKLKTAKIKVKEDLKTLQELKILVDFDDKGYLLQIFTKPVQDRPTL 347
Query: 798 FIEIIQR 818
F+E+IQR
Sbjct: 348 FLEVIQR 354
>sp|Q5BKL0|HPPD_XENTR 4-hydroxyphenylpyruvate dioxygenase OS=Xenopus tropicalis
GN=hpd PE=2 SV=1
Length = 394
Score = 152 bits (382), Expect = 6e-036
Identities = 97/254 (38%), Positives = 147/254 (57%), Gaps = 16/254 (6%)
Frame = +3
Query: 87 FSISVSNGAVPSSPPILLND---AVTISEVKLYGDVVLRYVSYNKAVTSVFLPRF-EPVE 254
F + +GAV P + D V + ++ YGD + Y VFLP + EP+
Sbjct: 107 FQKAKDHGAVVVREPWIEEDEGGKVKYAVLQTYGDTTHTLLEYLGPYRGVFLPGYKEPLF 166
Query: 255 DTSSFP-LDYG-ITRLDHAVGNVP--ELVPALTYLATFTGFHQFAEFTADDVGTAESGLN 422
P L G ++ +DH VGN P E+VP + + FH+F + T S L
Sbjct: 167 RDPLLPTLPSGCLSFIDHIVGNQPDNEMVPIVEWYQKCLLFHRFWSVDDKQIHTEYSSLR 226
Query: 423 SAVLANNDETVLLPINEPVHGTRRKSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKR 602
S V+ N +ET+ +PINEP G ++KSQIQ Y+++ AGVQH+AL + +I + ++ ++ R
Sbjct: 227 SIVVTNYEETIKMPINEPAAG-KKKSQIQEYVDYYGSAGVQHIALNTSNIIKAVKNLKSR 285
Query: 603 SGVGGFDFMPSPPPTYYKNLKKRV--GDVLSEEEIKECEELGILVDRDDQGTLLQIFTKP 776
G +F+ S P TYY+ L+K++ + +E++ +EL ILVD DD+G LLQIFTKP
Sbjct: 286 ----GIEFL-SAPDTYYEELRKKLKTAKITVKEDLNVLQELKILVDYDDKGYLLQIFTKP 340
Query: 777 LGDRPTIFIEIIQR 818
+ DRPT+F+E+IQR
Sbjct: 341 MQDRPTLFLEVIQR 354
>sp|Q6CDR5|HPPD_YARLI 4-hydroxyphenylpyruvate dioxygenase OS=Yarrowia lipolytica
GN=YALI0B21846g PE=3 SV=1
Length = 394
Score = 151 bits (380), Expect = 1e-035
Identities = 96/254 (37%), Positives = 146/254 (57%), Gaps = 16/254 (6%)
Frame = +3
Query: 87 FSISVSNGAVPSSPPILLNDA---VTISEVKLYGD---VVLRYVSYNKAVTSVFLPRFEP 248
FS +V G S P +L DA VT + + YGD ++ SY A F+
Sbjct: 119 FSAAVKKGVRVISEPKVLKDAHGSVTYAVISTYGDTTHTLIERGSYEGAFLPGFVDTSAN 178
Query: 249 VEDTSSFPLDYGITRLDHAVGNVP--ELVPALTYLATFTGFHQFAEFTADDVGTAESGLN 422
+ ++F + + +DH VGN E+ A Y GFH+F D+ T S L
Sbjct: 179 KDPIAAFLPNIELMHIDHCVGNQDWNEMDNACKYYEETLGFHRFWSVDDKDICTEFSALK 238
Query: 423 SAVLANNDETVLLPINEPVHGTRRKSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKR 602
S V+A+ +E + +P+NEP G ++KSQI+ Y++ +G G+QH+AL + I T+R++R R
Sbjct: 239 SVVMASPNEKIKMPVNEPAVG-KKKSQIEEYIDFYDGPGIQHIALRTDCILDTVRDLRAR 297
Query: 603 SGVGGFDFMPSPPPTYYKNLKKRV--GDVLSEEEIKECEELGILVDRDDQGTLLQIFTKP 776
G +F+ S P +YY+N+K+R+ + EE+ ++ + L IL+D D+ G LLQ+FTKP
Sbjct: 298 ----GVEFI-SVPGSYYENMKERLAKSSLKLEEKFEDIQALNILIDFDEGGYLLQLFTKP 352
Query: 777 LGDRPTIFIEIIQR 818
L DRPT+FIEIIQR
Sbjct: 353 LMDRPTVFIEIIQR 366
>sp|Q5EA20|HPPD_BOVIN 4-hydroxyphenylpyruvate dioxygenase OS=Bos taurus GN=HPD
PE=2 SV=3
Length = 393
Score = 150 bits (378), Expect = 2e-035
Identities = 98/230 (42%), Positives = 134/230 (58%), Gaps = 14/230 (6%)
Frame = +3
Query: 150 VTISEVKLYGDVVLRYVSYNKAVTSVFLPRFE--PVEDTSSFPL-DYGITRLDHAVGNVP 320
V + ++ YGD V T FLP FE P D L + +DH VGN P
Sbjct: 131 VKFAVLQTYGDTTHTLVE-KMNYTGRFLPGFEAPPFMDPQLSKLPSCSLEIIDHIVGNQP 189
Query: 321 --ELVPALTYLATFTGFHQFAEFTADDVGTAESGLNSAVLANNDETVLLPINEPVHGTRR 494
E+V A + FH+F V T S L S V+AN +E++ +PINEP G ++
Sbjct: 190 DQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSVVVANYEESIKMPINEPAPG-KK 248
Query: 495 KSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKRSGVGGFDFMPSPPPTYYKNL--KK 668
KSQIQ Y+++N GAGVQH+AL + DI +R +R+R G +F+ + P TYYK L K
Sbjct: 249 KSQIQEYVDYNGGAGVQHIALKTKDIITAIRHLRER----GVEFL-AVPSTYYKQLREKL 303
Query: 669 RVGDVLSEEEIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQR 818
++ + +E I EEL ILVD D++G LLQIFTKP+ DRPT+F+E+IQR
Sbjct: 304 KMAKIRVKENIDILEELKILVDYDEKGYLLQIFTKPMQDRPTLFLEVIQR 353
>sp|P32754|HPPD_HUMAN 4-hydroxyphenylpyruvate dioxygenase OS=Homo sapiens GN=HPD
PE=1 SV=2
Length = 393
Score = 147 bits (370), Expect = 1e-034
Identities = 84/179 (46%), Positives = 117/179 (65%), Gaps = 10/179 (5%)
Frame = +3
Query: 294 LDHAVGNVP--ELVPALTYLATFTGFHQFAEFTADDVGTAESGLNSAVLANNDETVLLPI 467
+DH VGN P E+V A + FH+F V T S L S V+AN +E++ +PI
Sbjct: 181 IDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPI 240
Query: 468 NEPVHGTRRKSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKRSGVGGFDFMPSPPPT 647
NEP G ++KSQIQ Y+++N GAGVQH+AL + DI +R +R+R G +F+ S P T
Sbjct: 241 NEPAPG-KKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRER----GLEFL-SVPST 294
Query: 648 YYKNLKKRV--GDVLSEEEIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQR 818
YYK L++++ + +E I EEL ILVD D++G LLQIFTKP+ DRPT+F+E+IQR
Sbjct: 295 YYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQR 353
>sp|Q872T7|HPPD_NEUCR 4-hydroxyphenylpyruvate dioxygenase OS=Neurospora crassa
GN=B23G1.170 PE=3 SV=1
Length = 412
Score = 146 bits (368), Expect = 2e-034
Identities = 105/280 (37%), Positives = 147/280 (52%), Gaps = 23/280 (8%)
Frame = +3
Query: 24 QHHDDDGNAATSASPEFKLVG--FSISVSNGAVPSSPPILLND----AVTISEVKLYGDV 185
+H + G+A + E V F +V+ GA P L D +V + ++ YGD
Sbjct: 113 EHLEKHGDAVKDVAFEVDNVDGVFHKAVAAGADVVQEPTTLTDKMHGSVRTAVIRTYGDT 172
Query: 186 VLRYVSYNKAVTSVFLPRFE---PVEDTSSFPLDYGITRLDHAVGNVP--ELVPALTYLA 350
+S FLP F P T P + R+DH VGN E+V A +
Sbjct: 173 THTLIS-RADYNGPFLPGFRTAAPSSATVQLP-SVPLARIDHCVGNQDWNEMVSACAFYE 230
Query: 351 TFTGFHQFAEFTADDVGTAESGLNSAVLANNDETVLLPINEPVHGTRRKSQIQTYLEHNE 530
FH+F + T S LNS V+A+ + V +PINEP G ++KSQI+ Y+ N
Sbjct: 231 QCLSFHRFWSVDDSQICTEFSALNSIVMASENNLVKMPINEPAPG-KKKSQIEEYVVFNS 289
Query: 531 GAGVQHLALTSGDIFRTLREMRKRSGVGGFDFMPSPPPTYYKNLKKRVGDVLSEEEIKE- 707
GAGVQH+AL + DI T+ MR R G +F+ + P TYY +++R+ E+KE
Sbjct: 290 GAGVQHIALLTPDIISTVSAMRAR----GVEFI-NVPSTYYDTIRQRLKTEKRGWELKED 344
Query: 708 ---CEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQR 818
++L IL+D D+ G LLQ+FTKPL DRPT+FIEIIQR
Sbjct: 345 LDTIQKLNILIDYDEGGYLLQLFTKPLMDRPTVFIEIIQR 384
>sp|P32755|HPPD_RAT 4-hydroxyphenylpyruvate dioxygenase OS=Rattus norvegicus
GN=Hpd PE=1 SV=3
Length = 393
Score = 145 bits (365), Expect = 5e-034
Identities = 94/233 (40%), Positives = 138/233 (59%), Gaps = 20/233 (8%)
Frame = +3
Query: 150 VTISEVKLYGD---VVLRYVSYNKAVTSVFLPRFE-PVEDTSSFPL--DYGITRLDHAVG 311
V + ++ YGD ++ ++Y T FLP FE P + P + +DH VG
Sbjct: 131 VKFAVLQTYGDTTHTLVEKINY----TGRFLPGFEAPTYKDTLLPKLPSCNLEIIDHIVG 186
Query: 312 NVP--ELVPALTYLATFTGFHQFAEFTADDVGTAESGLNSAVLANNDETVLLPINEPVHG 485
N P E+ A + FH+F V T S L S V+AN +E++ +PINEP G
Sbjct: 187 NQPDQEMESASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPG 246
Query: 486 TRRKSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKRSGVGGFDFMPSPPPTYYKNLK 665
R+KSQIQ Y+++N GAGVQH+AL + DI T+R +R+R G +F+ + P +YY+ L+
Sbjct: 247 -RKKSQIQEYVDYNGGAGVQHIALRTEDIITTIRHLRER----GMEFL-AVPSSYYRLLR 300
Query: 666 K--RVGDVLSEEEIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQR 818
+ + + +E + EEL ILVD D++G LLQIFTKP+ DRPT+F+E+IQR
Sbjct: 301 ENLKTSKIQVKENMDVLEELKILVDYDEKGYLLQIFTKPMQDRPTLFLEVIQR 353
>sp|Q27203|HPPD_TETTH 4-hydroxyphenylpyruvate dioxygenase OS=Tetrahymena
thermophila GN=TFA PE=3 SV=1
Length = 404
Score = 145 bits (365), Expect = 5e-034
Identities = 95/255 (37%), Positives = 144/255 (56%), Gaps = 18/255 (7%)
Frame = +3
Query: 87 FSISVSNGAVPSSPPILLND---AVTISEVKLYGDVVLRYVSYNKAVTSVFLPRF--EPV 251
++ ++ GA + PP L D +VTI+ V YG+V+ ++ N F+P F P+
Sbjct: 121 YNKAIQRGAKCAYPPQDLKDEHGSVTIAAVHTYGEVIHTFIQRND-YKGFFMPGFVAHPL 179
Query: 252 EDTSSFPL-DYGITRLDHAVGNVPE--LVPALTYLATFTGFHQFAEFTADDVGTAESGLN 422
+D + L D +DH VGN P+ + A + FH+F + T S L
Sbjct: 180 KDPLNNVLPDISYNYVDHIVGNQPDNMMTSAADWYEKTLDFHRFWSVDDSMIHTEFSSLR 239
Query: 423 SAVLANNDETVLLPINEPVHGTRRKSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKR 602
S V+ + D+ + +PINEP G +RKSQIQ Y++ G GVQH+AL + D+ T+ +R R
Sbjct: 240 SIVMTDYDQKIKMPINEPADG-KRKSQIQEYIDFYAGPGVQHIALNTSDVINTVEGLRAR 298
Query: 603 SGVGGFDFMPSPPPTYYKNLKKRV---GDVLSEEEIKECEELGILVDRDDQGTLLQIFTK 773
G +F+ S P +YY NL+K + + +E++ ++ ILVD D++G LLQIFTK
Sbjct: 299 ----GVEFL-SIPTSYYDNLRKALTAQTSITVKEDLDVLQKNHILVDYDEKGYLLQIFTK 353
Query: 774 PLGDRPTIFIEIIQR 818
P+ DRPT+F EIIQR
Sbjct: 354 PVEDRPTLFYEIIQR 368
>sp|Q96X22|HPPD_MAGGR 4-hydroxyphenylpyruvate dioxygenase OS=Magnaporthe grisea
GN=HPD4 PE=3 SV=1
Length = 419
Score = 144 bits (363), Expect = 9e-034
Identities = 96/257 (37%), Positives = 140/257 (54%), Gaps = 26/257 (10%)
Frame = +3
Query: 96 SVSNGAVPSSPPILLND----AVTISEVKLYGDVVLRYVSYNKAVTSVFLPRFEPVEDTS 263
+V GAV +PP L+D +VT++ ++ YGD +S + FLP F D +
Sbjct: 145 AVQQGAVSIAPPKTLSDKEHGSVTMAVIQTYGDTTHTLLSRDN-FRGTFLPGF---RDVN 200
Query: 264 SFPLDYG------ITRLDHAVGNV--PELVPALTYLATFTGFHQFAEFTADDVGTAESGL 419
P Y + R+DH VGN ++ A + FH+F + + T S L
Sbjct: 201 RQPAAYSALAPVPLQRIDHCVGNQDWDDMRAACDFYERCLSFHRFWSVDDNQISTDFSAL 260
Query: 420 NSAVLANNDETVLLPINEPVHGTRRKSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRK 599
NS V+A+ + V +PINEP G +++SQI+ Y+ N GAGVQH+AL + DI T+ MR
Sbjct: 261 NSIVMASPNNVVKMPINEPAKG-KKRSQIEEYVTFNSGAGVQHIALLTSDIITTVEAMRS 319
Query: 600 RSGVGGFDFMPSPPPTYYKNLKKRV----GDVLSEEEIKECEELGILVDRDDQGTLLQIF 767
R G +F+ P TYY +++R+ D +E+ IL+D D+ G LLQ+F
Sbjct: 320 R----GVEFI-EVPHTYYDTMRRRLKTEKRDWELQEDFDRLVRNNILIDYDEGGYLLQLF 374
Query: 768 TKPLGDRPTIFIEIIQR 818
T+PL DRPT+FIEIIQR
Sbjct: 375 TRPLMDRPTVFIEIIQR 391
>sp|Q02110|HPPD_PIG 4-hydroxyphenylpyruvate dioxygenase OS=Sus scrofa GN=HPD
PE=1 SV=4
Length = 393
Score = 144 bits (362), Expect = 1e-033
Identities = 82/183 (44%), Positives = 118/183 (64%), Gaps = 10/183 (5%)
Frame = +3
Query: 282 GITRLDHAVGNVP--ELVPALTYLATFTGFHQFAEFTADDVGTAESGLNSAVLANNDETV 455
G+ +DH VGN P E+ A + FH+F + T S L S V+AN +E++
Sbjct: 177 GLEIIDHIVGNQPDQEMESASQWYMRNLQFHRFWSVDDTQIHTEYSALRSVVMANYEESI 236
Query: 456 LLPINEPVHGTRRKSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKRSGVGGFDFMPS 635
+PINEP G ++KSQIQ Y+++N GAGVQH+AL + DI +R +R+R G +F+ +
Sbjct: 237 KMPINEPAPG-KKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRSLRER----GVEFL-A 290
Query: 636 PPPTYYKNLKKRV--GDVLSEEEIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEI 809
P TYYK L++++ + +E I EEL ILVD D++G LLQIFTKP+ DRPT+F+E+
Sbjct: 291 VPFTYYKQLQEKLKSAKIRVKESIDVLEELKILVDYDEKGYLLQIFTKPMQDRPTVFLEV 350
Query: 810 IQR 818
IQR
Sbjct: 351 IQR 353
>sp|O42764|HPPD_MYCGR 4-hydroxyphenylpyruvate dioxygenase OS=Mycosphaerella
graminicola GN=HPPD PE=3 SV=1
Length = 419
Score = 144 bits (361), Expect = 2e-033
Identities = 98/276 (35%), Positives = 145/276 (52%), Gaps = 19/276 (6%)
Frame = +3
Query: 27 HHDDDGNAATSASPEFK--LVGFSISVSNGAVPSSPP---ILLNDAVTISEVKLYGDVVL 191
H D G+ + E L + +V+NGA S P V + +K YGD
Sbjct: 123 HLDKHGDGVKDVAFEVDDVLAVYENAVANGAESVSSPHTDSCDEGDVISAAIKTYGDTTH 182
Query: 192 RYVSYNKAVTSVFLPRFE---PVEDTSSFPLDYGITRLDHAVGNV--PELVPALTYLATF 356
++ T FLP + V+ + F + +DH VGN E+ A +
Sbjct: 183 TFIQ-RTTYTGPFLPGYRSCTTVDSANKFLPPVNLEAIDHCVGNQDWDEMSDACDFYERC 241
Query: 357 TGFHQFAEFTADDVGTAESGLNSAVLANNDETVLLPINEPVHGTRRKSQIQTYLEHNEGA 536
GFH+F D+ T S L S V+++ ++ V +PINEP HG ++KSQI+ Y++ G
Sbjct: 242 LGFHRFWSVDDKDICTEFSALKSIVMSSPNQVVKMPINEPAHG-KKKSQIEEYVDFYNGP 300
Query: 537 GVQHLALTSGDIFRTLREMRKRSGVGGFDFMPSPPPTYYKNLKKRV--GDVLSEEEIKEC 710
GVQH+AL + +I + +R R G +F+ S P TYY+N++ R+ + EE
Sbjct: 301 GVQHIALRTPNIIEAVSNLRSR----GVEFI-SVPDTYYENMRLRLKAAGMKLEESFDII 355
Query: 711 EELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQR 818
++L IL+D D+ G LLQ+FTKPL DRPT+FIEIIQR
Sbjct: 356 QKLNILIDFDEGGYLLQLFTKPLMDRPTVFIEIIQR 391
>sp|P49429|HPPD_MOUSE 4-hydroxyphenylpyruvate dioxygenase OS=Mus musculus GN=Hpd
PE=1 SV=3
Length = 393
Score = 141 bits (355), Expect = 8e-033
Identities = 93/233 (39%), Positives = 136/233 (58%), Gaps = 20/233 (8%)
Frame = +3
Query: 150 VTISEVKLYGD---VVLRYVSYNKAVTSVFLPRFE-PVEDTSSFPL--DYGITRLDHAVG 311
V + ++ YGD ++ ++Y T FLP FE P + P + +DH VG
Sbjct: 131 VKFAVLQTYGDTTHTLVEKINY----TGRFLPGFEAPTYKDTLLPKLPRCNLEIIDHIVG 186
Query: 312 NVP--ELVPALTYLATFTGFHQFAEFTADDVGTAESGLNSAVLANNDETVLLPINEPVHG 485
N P E+ A + FH+F V T S L S V+ N +E++ +PINEP G
Sbjct: 187 NQPDQEMQSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVTNYEESIKMPINEPAPG 246
Query: 486 TRRKSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKRSGVGGFDFMPSPPPTYYKNLK 665
R+KSQIQ Y+++N GAGVQH+AL + DI +R +R+R G +F+ + P +YYK L+
Sbjct: 247 -RKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRER----GTEFL-AAPSSYYKLLR 300
Query: 666 KRV--GDVLSEEEIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQR 818
+ + + +E + EEL ILVD D++G LLQIFTKP+ DRPT+F+E+IQR
Sbjct: 301 ENLKSAKIQVKESMDVLEELHILVDYDEKGYLLQIFTKPMQDRPTLFLEVIQR 353
>sp|Q60Y65|HPPD_CAEBR 4-hydroxyphenylpyruvate dioxygenase OS=Caenorhabditis
briggsae GN=hpd-1 PE=3 SV=1
Length = 393
Score = 139 bits (350), Expect = 3e-032
Identities = 89/234 (38%), Positives = 131/234 (55%), Gaps = 14/234 (5%)
Frame = +3
Query: 141 NDAVTISEVKLYGD---VVLRYVSYNKAVTSVFLPRFEPVEDTSSFPLDYGITRLDHAVG 311
N +V + ++ YG+ +L Y A F P P S P G+ LDH VG
Sbjct: 127 NGSVRFATLRTYGETDHTLLERKKYKGAFLPGFKPHPMPPTFFHSLP-RVGLNFLDHCVG 185
Query: 312 NVPEL--VPALTYLATFTGFHQFAEFTADDVGTAESGLNSAVLANNDETVLLPINEPVHG 485
N P+L PA+ + FH+F + T S L S V+ N +ET+ +PINEP
Sbjct: 186 NQPDLQMAPAVEWYENILKFHRFWSVDDSMIHTEYSALRSIVVTNFEETIKMPINEPASS 245
Query: 486 TRRK-SQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKRSGVGGFDFMPSPPPTYYKNL 662
++ SQIQ ++++ G+GVQH+AL + DI + +R R G +F+ S P +YY NL
Sbjct: 246 NKKAVSQIQEFVDYYGGSGVQHIALNTTDIITAIEALRAR----GCEFL-SIPSSYYDNL 300
Query: 663 KKR--VGDVLSEEEIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIFIEIIQR 818
++R V + +E++ ++L ILVD D+ G LLQIF+KP DRPT+F+EIIQR
Sbjct: 301 RQRLSVSSMKIKEDMDRLQKLHILVDFDENGYLLQIFSKPCQDRPTLFLEIIQR 354
>sp|Q53586|HPPD_STRAW 4-hydroxyphenylpyruvate dioxygenase OS=Streptomyces
avermitilis GN=hpd PE=1 SV=2
Length = 381
Score = 136 bits (342), Expect = 3e-031
Identities = 94/250 (37%), Positives = 125/250 (50%), Gaps = 14/250 (5%)
Frame = +3
Query: 96 SVSNGAVPSSPPILLND---AVTISEVKLYGDVVLRYVSYNKAVTSVFLPRFEPVEDTSS 266
++ +GA + P L D V ++ + YG V +LP +
Sbjct: 117 AIEHGARSVAEPYELKDEHGTVVLAAIATYGKTRHTLVD-RTGYDGPYLPGYVAAAPIVE 175
Query: 267 FPLDYGITRLDHAVGNVP--ELVPALTYLATFTGFHQFAEFTADDVGTAESGLNSAVLAN 440
P +DH VGNV + + + GF EF DD+ T S L S V+A+
Sbjct: 176 PPAHRTFQAIDHCVGNVELGRMNEWVGFYNKVMGFTNMKEFVGDDIATEYSALMSKVVAD 235
Query: 441 NDETVLLPINEPVHGTRRKSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKRSGVGGF 620
V PINEP ++KSQI YLE GAGVQH+AL +GDI T+R MR G
Sbjct: 236 GTLKVKFPINEPAL-AKKKSQIDEYLEFYGGAGVQHIALNTGDIVETVRTMR----AAGV 290
Query: 621 DFMPSPPPTYYKNLKKRVGDVLSEEEIKECEELGILVDRDDQGTLLQIFTKPLGDRPTIF 800
F+ + P +YY L + VGD + + EL IL DRD+ G LLQIFTKP+ DRPT+F
Sbjct: 291 QFLDT-PDSYYDTLGEWVGD--TRVPVDTLRELKILADRDEDGYLLQIFTKPVQDRPTVF 347
Query: 801 IEIIQRIGCM 830
EII+R G M
Sbjct: 348 FEIIERHGSM 357
>sp|Q1E803|HPPD_COCIM 4-hydroxyphenylpyruvate dioxygenase OS=Coccidioides
immitis GN=TCRP PE=3 SV=1
Length = 399
Score = 136 bits (341), Expect = 3e-031
Identities = 93/255 (36%), Positives = 140/255 (54%), Gaps = 19/255 (7%)
Frame = +3
Query: 87 FSISVSNGAVPSSPPILLND---AVTISEVKLYGDVVLRYVSYNKAVTSVFLPRF---EP 248
FS +V NGA S + D + ++ ++ YG+ + F+P +
Sbjct: 124 FSAAVRNGAEVVSDVRTVEDEDGQIKMATIRTYGETTHTLIE-RSGYRGGFMPGYRMESN 182
Query: 249 VEDTSSFPLDYGITRLDHAVGNV--PELVPALTYLATFTGFHQFAEFTADDVGTAESGLN 422
V+ TS F + R+DH VGN E+ Y GFH+F D+ T S L
Sbjct: 183 VDATSKFLPKVVLERIDHCVGNQDWDEMERVCDYYEKILGFHRFWSVDDKDICTEFSALK 242
Query: 423 SAVLANNDETVLLPINEPVHGTRRKSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKR 602
S V+A+ ++ V +PINEP G +++SQI+ Y++ GAGVQH+AL + +I + ++ R
Sbjct: 243 SIVMASPNDIVKMPINEPAKG-KKQSQIEEYVDFYNGAGVQHIALRTNNIIDAITNLKAR 301
Query: 603 SGVGGFDFMPSPPPTYYKNLK---KRVGDVLSEEEIKECEELGILVDRDDQGTLLQIFTK 773
G +F+ P TYY+++K KR G VL +E+ + + L IL+D D+ G LLQ+FTK
Sbjct: 302 ----GTEFI-KVPETYYEDMKIRLKRQGLVL-DEDFETLKSLDILIDFDENGYLLQLFTK 355
Query: 774 PLGDRPTIFIEIIQR 818
L DRPT+FIEIIQR
Sbjct: 356 HLMDRPTVFIEIIQR 370
>sp|Q00415|HPPD_COCP7 4-hydroxyphenylpyruvate dioxygenase OS=Coccidioides
posadasii (strain C735) GN=TCRP PE=2 SV=1
Length = 399
Score = 135 bits (338), Expect = 7e-031
Identities = 95/255 (37%), Positives = 140/255 (54%), Gaps = 19/255 (7%)
Frame = +3
Query: 87 FSISVSNGAVPSSPPILLND---AVTISEVKLYGDVVLRYVSYNKAVTSVFLP--RFEPV 251
FS +V NGA S + D + ++ ++ YG+ + F+P R E
Sbjct: 124 FSAAVRNGAEVVSDVRTVEDEDGQIKMATIRTYGETTHTLIE-RSGYRGGFMPGYRMESN 182
Query: 252 ED-TSSFPLDYGITRLDHAVGNV--PELVPALTYLATFTGFHQFAEFTADDVGTAESGLN 422
D TS F + R+DH VGN E+ Y GFH+F D+ T S L
Sbjct: 183 ADATSKFLPKVVLERIDHCVGNQDWDEMERVCDYYEKILGFHRFWSVDDKDICTEFSALK 242
Query: 423 SAVLANNDETVLLPINEPVHGTRRKSQIQTYLEHNEGAGVQHLALTSGDIFRTLREMRKR 602
S V+A+ ++ V +PINEP G +++SQI+ Y++ GAGVQH+AL + +I + ++ R
Sbjct: 243 SIVMASPNDIVKMPINEPAKG-KKQSQIEEYVDFYNGAGVQHIALRTNNIIDAITNLKAR 301
Query: 603 SGVGGFDFMPSPPPTYYKNLK---KRVGDVLSEEEIKECEELGILVDRDDQGTLLQIFTK 773
G +F+ P TYY+++K KR G VL +E+ + + L IL+D D+ G LLQ+FTK
Sbjct: 302 ----GTEFI-KVPETYYEDMKIRLKRQGLVL-DEDFETLKSLDILIDFDENGYLLQLFTK 355
Query: 774 PLGDRPTIFIEIIQR 818
L DRPT+FIEIIQR
Sbjct: 356 HLMDRPTVFIEIIQR 370
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 164,931,892,944
Number of Sequences: 518415
Number of Extensions: 164931892944
Number of Successful Extensions: 1021520109
Number of sequences better than 0.0: 0
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