BLASTX 7.6.2
Query= UN44046 /QuerySize=840
(839 letters)
Database: UniProt/SwissProt;
518,415 sequences; 182,829,261 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q0D2K0|NIPA4_HUMAN Magnesium transporter NIPA4 OS=Homo sapien... 83 2e-015
sp|Q8BZF2|NIPA4_MOUSE Magnesium transporter NIPA4 OS=Mus musculu... 78 6e-014
sp|Q8N8Q9|NIPA2_HUMAN Magnesium transporter NIPA2 OS=Homo sapien... 74 1e-012
sp|Q5R7Q3|NIPA2_PONAB Magnesium transporter NIPA2 OS=Pongo abeli... 74 1e-012
sp|Q3SWX0|NIPA2_BOVIN Magnesium transporter NIPA2 OS=Bos taurus ... 73 2e-012
sp|Q9JJC8|NIPA2_MOUSE Magnesium transporter NIPA2 OS=Mus musculu... 69 4e-011
sp|Q8BMW7|NIPA3_MOUSE Magnesium transporter NIPA3 OS=Mus musculu... 67 2e-010
sp|Q5RDB8|NIPA3_PONAB Magnesium transporter NIPA3 OS=Pongo abeli... 67 2e-010
sp|Q6NVV3|NIPA3_HUMAN Magnesium transporter NIPA3 OS=Homo sapien... 66 3e-010
sp|Q7RTP0|NIPA1_HUMAN Magnesium transporter NIPA1 OS=Homo sapien... 60 1e-008
sp|Q8BHK1|NIPA1_MOUSE Magnesium transporter NIPA1 OS=Mus musculu... 60 1e-008
>sp|Q0D2K0|NIPA4_HUMAN Magnesium transporter NIPA4 OS=Homo sapiens GN=NIPAL4
PE=1 SV=3
Length = 466
Score = 83 bits (204), Expect = 2e-015
Identities = 39/90 (43%), Positives = 57/90 (63%), Gaps = 5/90 (5%)
Frame = -3
Query: 513 FWQKALDTFNTAVIFPVYFVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTF 334
F +ALD FNT+++FP+Y+V FTT + +S+I+FK+W S S + IA L GFVTI+ G F
Sbjct: 343 FLNRALDIFNTSLVFPIYYVFFTTVVVTSSIILFKEWYSMSAVDIAGTLSGFVTIILGVF 402
Query: 333 LLHKTKDMGNSASG-----RGAPSTPRDNP 259
+LH KD+ S + + P +P P
Sbjct: 403 MLHAFKDLDISCASLPHMHKNPPPSPAPEP 432
Score = 60 bits (145), Expect = 1e-008
Identities = 27/96 (28%), Positives = 57/96 (59%)
Frame = -3
Query: 819 VIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLTVMSVKAVAIAIKLTFSEMNQFKYFQT 640
+++ L+LIF PRYG+ ++++Y+ ICS++G+ +V +VK + I IK F + ++
Sbjct: 267 LVSCLILIFVIAPRYGQRNILIYIIICSVIGAFSVAAVKGLGITIKNFFQGLPVVRHPLP 326
Query: 639 WIFIIVVTVCCILQINYLNKVNKKLSNFHWLSLYYL 532
+I +++ + Q+N+LN+ + +YY+
Sbjct: 327 YILSLILALSLSTQVNFLNRALDIFNTSLVFPIYYV 362
>sp|Q8BZF2|NIPA4_MOUSE Magnesium transporter NIPA4 OS=Mus musculus GN=Nipal4
PE=1 SV=1
Length = 406
Score = 78 bits (191), Expect = 6e-014
Identities = 32/68 (47%), Positives = 49/68 (72%)
Frame = -3
Query: 513 FWQKALDTFNTAVIFPVYFVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTF 334
F +ALD FNT+++FP+Y+V FTT + +S+++FK+W + S + I L GFVTI+ G F
Sbjct: 283 FLNRALDIFNTSLVFPIYYVFFTTVVVASSIVLFKEWYTMSAVDIVGTLSGFVTIILGVF 342
Query: 333 LLHKTKDM 310
+LH KD+
Sbjct: 343 MLHAFKDL 350
Score = 64 bits (154), Expect = 1e-009
Identities = 28/96 (29%), Positives = 59/96 (61%)
Frame = -3
Query: 819 VIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLTVMSVKAVAIAIKLTFSEMNQFKYFQT 640
V++ L+LIF PRYG+ ++++Y+ ICS++GS +V +VK + + I+ F + ++
Sbjct: 207 VVSCLILIFIVAPRYGQRNILIYIIICSVIGSFSVTAVKGLGVTIRNFFQGLPVVRHPLP 266
Query: 639 WIFIIVVTVCCILQINYLNKVNKKLSNFHWLSLYYL 532
+I +++ + I+Q+N+LN+ + +YY+
Sbjct: 267 YILSLILGLSIIIQVNFLNRALDIFNTSLVFPIYYV 302
>sp|Q8N8Q9|NIPA2_HUMAN Magnesium transporter NIPA2 OS=Homo sapiens GN=NIPA2 PE=2
SV=1
Length = 360
Score = 74 bits (179), Expect = 1e-012
Identities = 36/96 (37%), Positives = 58/96 (60%)
Frame = -3
Query: 819 VIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLTVMSVKAVAIAIKLTFSEMNQFKYFQT 640
VI L+LIF PR+G+T+++VY+ ICS++G+ +V VK + IAIK F+ ++
Sbjct: 159 VIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLA 218
Query: 639 WIFIIVVTVCCILQINYLNKVNKKLSNFHWLSLYYL 532
WI ++ + VC QINYLN+ + +YY+
Sbjct: 219 WILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYV 254
Score = 67 bits (161), Expect = 2e-010
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = -3
Query: 549 LSLYYL*VSLLYFWQKALDTFNTAVIFPVYFVMFTTFTIIASMIMFKDWASQSGLKIATE 370
LSL + + + +ALD FNT+++ P+Y+V FTT + S I+FK+W +
Sbjct: 223 LSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGT 282
Query: 369 LCGFVTILSGTFLLHKTKDMGNS 301
L GF TI+ G FLLH KD+ S
Sbjct: 283 LSGFFTIIVGIFLLHAFKDVSFS 305
>sp|Q5R7Q3|NIPA2_PONAB Magnesium transporter NIPA2 OS=Pongo abelii GN=NIPA2 PE=2
SV=1
Length = 360
Score = 74 bits (179), Expect = 1e-012
Identities = 36/96 (37%), Positives = 58/96 (60%)
Frame = -3
Query: 819 VIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLTVMSVKAVAIAIKLTFSEMNQFKYFQT 640
VI L+LIF PR+G+T+++VY+ ICS++G+ +V VK + IAIK F+ ++
Sbjct: 159 VIVALILIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELFAGKPVLRHPLA 218
Query: 639 WIFIIVVTVCCILQINYLNKVNKKLSNFHWLSLYYL 532
WI ++ + VC QINYLN+ + +YY+
Sbjct: 219 WILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYV 254
Score = 67 bits (161), Expect = 2e-010
Identities = 33/83 (39%), Positives = 48/83 (57%)
Frame = -3
Query: 549 LSLYYL*VSLLYFWQKALDTFNTAVIFPVYFVMFTTFTIIASMIMFKDWASQSGLKIATE 370
LSL + + + +ALD FNT+++ P+Y+V FTT + S I+FK+W +
Sbjct: 223 LSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDDVIGT 282
Query: 369 LCGFVTILSGTFLLHKTKDMGNS 301
L GF TI+ G FLLH KD+ S
Sbjct: 283 LSGFFTIIVGIFLLHAFKDVSFS 305
>sp|Q3SWX0|NIPA2_BOVIN Magnesium transporter NIPA2 OS=Bos taurus GN=NIPA2 PE=2
SV=1
Length = 360
Score = 73 bits (178), Expect = 2e-012
Identities = 36/96 (37%), Positives = 59/96 (61%)
Frame = -3
Query: 819 VIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLTVMSVKAVAIAIKLTFSEMNQFKYFQT 640
VI L+LIF PR+G+T+++VY+ ICS++G+++V K + IAIK F+ ++ T
Sbjct: 159 VIVSLILIFVVGPRHGQTNILVYITICSVIGAVSVSCAKGLGIAIKELFAGKPVLQHPLT 218
Query: 639 WIFIIVVTVCCILQINYLNKVNKKLSNFHWLSLYYL 532
WI ++ + VC QINYLN+ + +YY+
Sbjct: 219 WILLLSLIVCVSTQINYLNRALDIFNTSIVTPIYYV 254
Score = 69 bits (166), Expect = 5e-011
Identities = 35/85 (41%), Positives = 49/85 (57%)
Frame = -3
Query: 549 LSLYYL*VSLLYFWQKALDTFNTAVIFPVYFVMFTTFTIIASMIMFKDWASQSGLKIATE 370
LSL + + + +ALD FNT+++ P+Y+V FTT I S I+FK+W +
Sbjct: 223 LSLIVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVITCSAILFKEWQDMPVDDVIGT 282
Query: 369 LCGFVTILSGTFLLHKTKDMGNSAS 295
L GF TI+ G FLLH KD+ S S
Sbjct: 283 LSGFFTIIVGIFLLHAFKDVSFSLS 307
>sp|Q9JJC8|NIPA2_MOUSE Magnesium transporter NIPA2 OS=Mus musculus GN=Nipa2 PE=1
SV=1
Length = 359
Score = 69 bits (167), Expect = 4e-011
Identities = 34/96 (35%), Positives = 55/96 (57%)
Frame = -3
Query: 819 VIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLTVMSVKAVAIAIKLTFSEMNQFKYFQT 640
VI L+ IF PR+G+T+++VY+ ICS++G+ +V VK + IAIK + ++
Sbjct: 159 VIVALIFIFVVGPRHGQTNILVYITICSVIGAFSVSCVKGLGIAIKELLAGKPVLQHPLA 218
Query: 639 WIFIIVVTVCCILQINYLNKVNKKLSNFHWLSLYYL 532
WI + + VC QINYLN+ + +YY+
Sbjct: 219 WILLFSLVVCVSTQINYLNRALDIFNTSIVTPIYYV 254
Score = 68 bits (165), Expect = 6e-011
Identities = 34/87 (39%), Positives = 51/87 (58%), Gaps = 3/87 (3%)
Frame = -3
Query: 552 WLSLYYL*VSL---LYFWQKALDTFNTAVIFPVYFVMFTTFTIIASMIMFKDWASQSGLK 382
W+ L+ L V + + + +ALD FNT+++ P+Y+V FTT + S I+FK+W
Sbjct: 219 WILLFSLVVCVSTQINYLNRALDIFNTSIVTPIYYVFFTTSVLTCSAILFKEWQDMPVDD 278
Query: 381 IATELCGFVTILSGTFLLHKTKDMGNS 301
+ L GF TI+ G FLLH KD+ S
Sbjct: 279 VIGTLSGFFTIIVGIFLLHAFKDVSFS 305
>sp|Q8BMW7|NIPA3_MOUSE Magnesium transporter NIPA3 OS=Mus musculus GN=Nipal1
PE=1 SV=2
Length = 416
Score = 67 bits (161), Expect = 2e-010
Identities = 29/67 (43%), Positives = 43/67 (64%)
Frame = -3
Query: 513 FWQKALDTFNTAVIFPVYFVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTF 334
+ KALDTFNT+++ P+Y+V FT+ + S I+F++W I L GF TI++G F
Sbjct: 293 YLNKALDTFNTSLVTPIYYVFFTSMVVTCSAILFQEWYGMKAGDIIGTLSGFFTIINGIF 352
Query: 333 LLHKTKD 313
LLH K+
Sbjct: 353 LLHAFKN 359
Score = 62 bits (148), Expect = 6e-009
Identities = 33/92 (35%), Positives = 52/92 (56%)
Frame = -3
Query: 807 LVLIFYYEPRYGKTHLIVYVGICSLMGSLTVMSVKAVAIAIKLTFSEMNQFKYFQTWIFI 628
LVLI P+ G+T+++VY+ ICSL+G+ +V SVK + IAIK +K +I +
Sbjct: 221 LVLILIVAPKKGQTNILVYIAICSLIGAFSVSSVKGLGIAIKELLERKPVYKDPLFFILL 280
Query: 627 IVVTVCCILQINYLNKVNKKLSNFHWLSLYYL 532
++ + QINYLNK + +YY+
Sbjct: 281 TMLALSVTTQINYLNKALDTFNTSLVTPIYYV 312
>sp|Q5RDB8|NIPA3_PONAB Magnesium transporter NIPA3 OS=Pongo abelii GN=NIPAL1
PE=2 SV=1
Length = 410
Score = 67 bits (161), Expect = 2e-010
Identities = 29/67 (43%), Positives = 43/67 (64%)
Frame = -3
Query: 513 FWQKALDTFNTAVIFPVYFVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTF 334
+ KALDTFNT+++ P+Y+V FT+ + S I+F++W + I L GF TI+ G F
Sbjct: 293 YLNKALDTFNTSIVTPIYYVFFTSMVVTCSAILFQEWYGMTAGDIIGTLSGFFTIIIGIF 352
Query: 333 LLHKTKD 313
LLH K+
Sbjct: 353 LLHAFKN 359
Score = 64 bits (154), Expect = 1e-009
Identities = 33/92 (35%), Positives = 53/92 (57%)
Frame = -3
Query: 807 LVLIFYYEPRYGKTHLIVYVGICSLMGSLTVMSVKAVAIAIKLTFSEMNQFKYFQTWIFI 628
LVLI P+ G+T+++VY+ ICSL+G+ +V SVK + IAIK +K+ ++ +
Sbjct: 221 LVLILIVAPKKGQTNILVYISICSLIGAFSVSSVKGLGIAIKELIEWKPVYKHPLVFVLL 280
Query: 627 IVVTVCCILQINYLNKVNKKLSNFHWLSLYYL 532
V+ + QINYLNK + +YY+
Sbjct: 281 AVLVLSVTTQINYLNKALDTFNTSIVTPIYYV 312
>sp|Q6NVV3|NIPA3_HUMAN Magnesium transporter NIPA3 OS=Homo sapiens GN=NIPAL1
PE=2 SV=1
Length = 410
Score = 66 bits (159), Expect = 3e-010
Identities = 29/67 (43%), Positives = 43/67 (64%)
Frame = -3
Query: 513 FWQKALDTFNTAVIFPVYFVMFTTFTIIASMIMFKDWASQSGLKIATELCGFVTILSGTF 334
+ KALDTFNT+++ P+Y+V FT+ + S I+F++W + I L GF TI+ G F
Sbjct: 293 YLNKALDTFNTSLVTPIYYVFFTSMVVTCSAILFQEWYGMTAGDIIGTLSGFFTIIIGIF 352
Query: 333 LLHKTKD 313
LLH K+
Sbjct: 353 LLHAFKN 359
Score = 64 bits (154), Expect = 1e-009
Identities = 33/92 (35%), Positives = 53/92 (57%)
Frame = -3
Query: 807 LVLIFYYEPRYGKTHLIVYVGICSLMGSLTVMSVKAVAIAIKLTFSEMNQFKYFQTWIFI 628
LVLI P+ G+T+++VY+ ICSL+G+ +V SVK + IAIK +K+ ++ +
Sbjct: 221 LVLILIVAPKKGQTNILVYISICSLIGAFSVSSVKGLGIAIKELIEWKPVYKHPLVFVLL 280
Query: 627 IVVTVCCILQINYLNKVNKKLSNFHWLSLYYL 532
V+ + QINYLNK + +YY+
Sbjct: 281 AVLVLSVTTQINYLNKALDTFNTSLVTPIYYV 312
>sp|Q7RTP0|NIPA1_HUMAN Magnesium transporter NIPA1 OS=Homo sapiens GN=NIPA1 PE=1
SV=1
Length = 329
Score = 60 bits (145), Expect = 1e-008
Identities = 34/114 (29%), Positives = 63/114 (55%), Gaps = 2/114 (1%)
Frame = -3
Query: 831 LCCDVIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLTVMSVKAVAIAIK--LTFSEMNQ 658
LC ++ +L+LIF+ P +G T+++VY+ ICSL+GS TV S K + +A + L + +Q
Sbjct: 165 LCIVLLMLLLLIFWIAPAHGPTNIMVYISICSLLGSFTVPSTKGIGLAAQDILHNNPSSQ 224
Query: 657 FKYFQTWIFIIVVTVCCILQINYLNKVNKKLSNFHWLSLYYL*VSLLYFWQKAL 496
+ + V+ I+Q Y+NK + + + ++YY+ + L A+
Sbjct: 225 RALCLCLVLLAVLGCSIIVQFRYINKALECFDSSVFGAIYYVVFTTLVLLASAI 278
>sp|Q8BHK1|NIPA1_MOUSE Magnesium transporter NIPA1 OS=Mus musculus GN=Nipa1 PE=1
SV=1
Length = 323
Score = 60 bits (145), Expect = 1e-008
Identities = 34/114 (29%), Positives = 63/114 (55%), Gaps = 2/114 (1%)
Frame = -3
Query: 831 LCCDVIAVLVLIFYYEPRYGKTHLIVYVGICSLMGSLTVMSVKAVAIAIK--LTFSEMNQ 658
LC ++ +L+LIF+ P +G T+++VY+ ICSL+GS TV S K + +A + L + +Q
Sbjct: 159 LCIVLLMLLLLIFWIAPAHGPTNIMVYISICSLLGSFTVPSTKGIGLAAQDILHNNPSSQ 218
Query: 657 FKYFQTWIFIIVVTVCCILQINYLNKVNKKLSNFHWLSLYYL*VSLLYFWQKAL 496
+ + V+ I+Q Y+NK + + + ++YY+ + L A+
Sbjct: 219 RALCLCLVLLAVLGCSIIVQFRYINKALECFDSSVFGAIYYVVFTTLVLLASAI 272
Database: UniProt/SwissProt
Posted date: Sat Aug 07 14:36:18 2010
Number of letters in database: 182,829,261
Number of sequences in database: 518,415
Lambda K H
0.267 0.041 0.140
Gapped
Lambda K H
0.267 0.041 0.140
Matrix: blosum62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 167,919,208,508
Number of Sequences: 518415
Number of Extensions: 167919208508
Number of Successful Extensions: 1034094832
Number of sequences better than 0.0: 0
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